hydralazine and glyburide

hydralazine has been researched along with glyburide in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's8 (61.54)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abe, I; Fujii, K; Fujishima, M; Nagao, T; Ohya, Y; Setoguchi, M1
Bakhtiarian, A; Djahanguiri, B; Rahgozar, M; Toroudi, HP1
Asakura, M; Asanuma, H; Hori, M; Kim, J; Kitakaze, M; Liao, Y; Minamino, T; Node, K; Ogai, A; Ogita, H; Sanada, S; Takashima, S1
Chang, NC; Lee, TM; Lin, MS; Tsai, CH1
Chen, Y; Huang, GY; Huang, SH; Moore, PK; Shi, YX; Yao, T; Zhu, YC; Zhu, YZ1

Reviews

1 review(s) available for hydralazine and glyburide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

12 other study(ies) available for hydralazine and glyburide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Impaired action of levcromakalim on ATP-sensitive K+ channels in mesenteric artery cells from spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:6

    Topics: Animals; Benzopyrans; Blood Pressure; Body Weight; Cromakalim; Dose-Response Relationship, Drug; Glyburide; Hydralazine; Membrane Potentials; Mesenteric Arteries; Parasympatholytics; Patch-Clamp Techniques; Potassium Channels; Pulse; Pyrroles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity

1996
Potassium channel modulators and indomethacin-induced gastric ulceration in rats.
    Scandinavian journal of gastroenterology, 1999, Volume: 34, Issue:10

    Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Diazoxide; Enalapril; Gastric Mucosa; Glyburide; Hydralazine; Indomethacin; Male; Peptic Ulcer; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilator Agents

1999
Opening of the adenosine triphosphate-sensitive potassium channel attenuates cardiac remodeling induced by long-term inhibition of nitric oxide synthesis: role of 70-kDa S6 kinase and extracellular signal-regulated kinase.
    Journal of the American College of Cardiology, 2002, Sep-04, Volume: 40, Issue:5

    Topics: Adenosine Triphosphate; Animals; Blood Pressure; Body Weight; Cardiomegaly; Glyburide; Hydralazine; Mitogen-Activated Protein Kinases; NG-Nitroarginine Methyl Ester; Nicorandil; Nitric Oxide; Potassium Channels; Rats; Rats, Inbred WKY; Ribosomal Protein S6 Kinases

2002
Effect of pravastatin on left ventricular mass in the two-kidney, one-clip hypertensive rats.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Natriuretic Factor; Echocardiography; Gene Expression Regulation; Glyburide; Heart Ventricles; Hydralazine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Renal; Hypertrophy, Left Ventricular; Male; Nicorandil; Potassium Channels; Pravastatin; Rats; Rats, Wistar; Vasodilator Agents

2006
Chronic sodium hydrosulfide treatment decreases medial thickening of intramyocardial coronary arterioles, interstitial fibrosis, and ROS production in spontaneously hypertensive rats.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:4

    Topics: Animals; Antihypertensive Agents; Blood Chemical Analysis; Blood Pressure; Cardiomegaly; Cardiotonic Agents; Collagen; Coronary Vessels; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fibrosis; Glyburide; Heart Rate; Heart Ventricles; Hydralazine; Hypertension; Male; Myocardium; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Sulfhydryl Compounds; Sulfides; Ventricular Dysfunction, Left; Ventricular Remodeling

2007