hydralazine and felodipine

hydralazine has been researched along with felodipine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199010 (41.67)18.7374
1990's7 (29.17)18.2507
2000's5 (20.83)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Adams, MA; Friberg, P; Thompson, KE1
Jacinto, SM; Jandhyala, BS1
Cross, AJ; Davies, EM; DeSouza, RJ; Green, AR1
Björkman, JA; Ek, L; Gustafsson, D; Ljung, B; Nordlander, M1
Strauer, BE1
Chintala, MS; Jandhyala, BS1
DiBona, GF2
Dahlöf, B; Gudbrandsson, T; Hansson, L; Hellsing, T; Kullman, S; Kuylenstierna, J; Leppert, J; Möller, B; Skogström, K; Svensson, A1
Littler, WA; Smith, SA1
Andersson, OK; Granérus, G; Hedner, T1
Hedner, T1
Muir, AL; Wathen, CG1
Hannan, WJ; Muir, AL; Wathen, CG1
Nordlander, M1
Cohn, JN1

Reviews

3 review(s) available for hydralazine and felodipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antihypertensive agents--the race for third place.
    Journal of clinical and hospital pharmacy, 1985, Volume: 10, Issue:2

    Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Diazoxide; Felodipine; Humans; Hydralazine; Indoramin; Labetalol; Minoxidil; Nicardipine; Nifedipine; Vasodilator Agents; Verapamil

1985
Vasodilators in heart failure. Conclusions from V-HeFT II and rationale for V-HeFT III.
    Drugs, 1994, Volume: 47 Suppl 4

    Topics: Clinical Trials as Topic; Drug Therapy, Combination; Enalapril; Exercise; Felodipine; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Norepinephrine; Oxygen Consumption; Prognosis; Stroke Volume; Survival Analysis

1994

Trials

4 trial(s) available for hydralazine and felodipine

ArticleYear
Antihypertensive effect of felodipine or hydralazine when added to beta-blocker therapy.
    Journal of cardiovascular pharmacology, 1988, Volume: 12, Issue:1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Nitrendipine; Random Allocation

1988
Felodipine vs hydralazine: a controlled trial as third line therapy in hypertension. Cooperative Study Group.
    British journal of clinical pharmacology, 1986, Volume: 21, Issue:6

    Topics: Adult; Aged; Antihypertensive Agents; Double-Blind Method; Felodipine; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Nifedipine; Random Allocation

1986
Clinical evaluation of felodipine in hypertensive patients previously treated with a triple drug regimen.
    Drugs, 1987, Volume: 34 Suppl 3

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Felodipine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Nitrendipine

1987
The use of felodipine in the treatment of severe hypertension.
    Drugs, 1987, Volume: 34 Suppl 3

    Topics: Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Felodipine; Female; Humans; Hydralazine; Hypertension; Male; Minoxidil; Nitrendipine; Random Allocation

1987

Other Studies

17 other study(ies) available for hydralazine and felodipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Vasodilators inhibit acute alpha 1-adrenergic receptor-induced trophic responses in the vasculature.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 20, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Blood Pressure; Drug Combinations; Felodipine; Heart Rate; Hydralazine; Male; Mesenteric Arteries; Methoxamine; Ornithine Decarboxylase; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Vasodilator Agents

1992
Evaluation of the effects of felodipine, verapamil and hydralazine on the survival rate of rats subjected to lethal effects of oxygen free radicals.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:4

    Topics: Animals; Blood Pressure; Creatine Kinase; Felodipine; Heart Rate; Hydralazine; Male; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Survival Rate; Verapamil; Xanthine; Xanthine Oxidase; Xanthines

1992
The effects of Ca2+ antagonists and hydralazine on central 5-hydroxytryptamine biochemistry and function in rats and mice.
    British journal of pharmacology, 1990, Volume: 99, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Chemistry; Calcium Channel Blockers; Felodipine; Hydralazine; Hydroxyindoleacetic Acid; Male; Methoxydimethyltryptamines; Mice; Mice, Inbred C57BL; Rats; Receptors, Serotonin; Serotonin; Species Specificity; Tetrahydronaphthalenes; Tranylcypromine; Tryptophan

1990
Acute haemodynamic effects of felodipine, verapamil and hydralazine in the anaesthetized dog.
    Pharmacology & toxicology, 1991, Volume: 68, Issue:4

    Topics: Animals; Catecholamines; Dogs; Felodipine; Hemodynamics; Hydralazine; Verapamil

1991
Significance of coronary circulation in hypertensive heart disease for development and prevention of heart failure.
    The American journal of cardiology, 1990, Apr-03, Volume: 65, Issue:14

    Topics: Adult; Animals; Cardiac Output, Low; Cardiomegaly; Coronary Circulation; Coronary Disease; Coronary Vessels; Felodipine; Humans; Hydralazine; Hypertension; Metoprolol; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance

1990
Comparative evaluation of the effects of felodipine, hydralazine, and naloxone on the survival rate in rats subjected to a "fixed volume" model of hemorrhagic shock.
    Circulatory shock, 1990, Volume: 32, Issue:3

    Topics: Animals; Blood Pressure; Blood Volume; Bloodletting; Felodipine; Heart Rate; Hematocrit; Hydralazine; Male; Naloxone; Rats; Rats, Inbred Strains; Shock, Hemorrhagic; Survival Rate

1990
Effects of vasodilator antihypertensive agents on renal function.
    Journal of cardiovascular pharmacology, 1987, Volume: 9 Suppl 1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Dogs; Felodipine; Hydralazine; Kidney; Kidney Function Tests; Minoxidil; Nitrendipine; Rats; Rats, Inbred SHR; Vasodilator Agents

1987
Felodipine in combination with a beta-blocker and a diuretic in chronic treatment of patients with refractory primary hypertension.
    Drugs, 1987, Volume: 34 Suppl 3

    Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Therapy, Combination; Felodipine; Heart Rate; Humans; Hydralazine; Hypertension; Male; Middle Aged; Nitrendipine; Renal Circulation

1987
Effects of felodipine on resistance and capacitance vessels in patients with essential hypertension.
    Drugs, 1985, Volume: 29 Suppl 2

    Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Blood Vessels; Electrocardiography; Felodipine; Heart Rate; Humans; Hydralazine; Hypertension; Middle Aged; Nifedipine; Nitroglycerin; Stroke Volume; Vascular Resistance

1985
Effects of felodipine on renal function in animals.
    Drugs, 1985, Volume: 29 Suppl 2

    Topics: Animals; Antihypertensive Agents; Dogs; Felodipine; Glomerular Filtration Rate; Hemodynamics; Hydralazine; Hypertension; Kidney; Nifedipine; Potassium; Rats; Rats, Inbred SHR; Renal Circulation; Sodium

1985
Haemodynamic effects of short and long term administration of felodipine in spontaneously hypertensive rats.
    Drugs, 1985, Volume: 29 Suppl 2

    Topics: Animals; Antihypertensive Agents; Cardiac Output; Coronary Circulation; Drug Administration Schedule; Felodipine; Female; Heart Rate; Hemodynamics; Hydralazine; Hypertension; Male; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reflex; Regional Blood Flow; Stroke Volume; Time Factors

1985