Compounds > hydralazine

hydralazine and eplerenone

hydralazine has been researched along with eplerenone in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's7 (70.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Endemann, DH; Iglarz, M; Savoia, C; Schiffrin, EL; Touyz, RM1
Fujita, T; Gotoda, T; Nagase, M; Nagase, T; Shibata, S; Yoshida, S1
Fujita, T; Kawachi, H; Nagase, M; Shibata, S; Yoshida, S1
Grossman, E; Kamari, Y; Koren, F; Peleg, E; Sharabi, Y; Shimoni, N1
Ando, K; Fujita, M; Fujita, T; Kawarazaki, H; Matsui, H; Nagae, A1
Fan, YY; Felder, RA; Fujisawa, Y; Hitomi, H; Kitada, K; Kohno, M; Nakano, D; Nishiyama, A; Noma, T; Ohsaki, H; Rafiq, K; Sherajee, SJ; Yatabe, J; Yatabe, M1
Deguchi, K; Hitomi, H; Kitada, K; Kobori, H; Lei, B; Masaki, T; Minamino, T; Mori, H; Nakano, D; Nishiyama, A1
Dorrance, AM; Jackson, WF; Pires, PW1
Gong, H; Li, H; Lu, Y; Ma, X; Wang, B; Wang, C; Wu, Z; Yan, Y; Zhang, X1

Reviews

1 review(s) available for hydralazine and eplerenone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for hydralazine and eplerenone

ArticleYear
Eplerenone prevents salt-induced vascular remodeling and cardiac fibrosis in stroke-prone spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:6

    Topics: Acetylcholine; Aldosterone; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Collagen; Dose-Response Relationship, Drug; Endothelium, Vascular; Eplerenone; Fibrosis; Heart; Hydralazine; Hypertension; Male; Mesenteric Arteries; Mineralocorticoid Receptor Antagonists; Myocardium; Natriuresis; Organ Size; Rats; Rats, Inbred SHR; Receptors, Mineralocorticoid; Sodium Chloride, Dietary; Spironolactone; Thiobarbituric Acid Reactive Substances; Tunica Media; Vasodilation

2004
Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 47, Issue:6

    Topics: Animals; Apoptosis; Biomarkers; Blood Pressure; Eplerenone; Fibrosis; Glomerulosclerosis, Focal Segmental; Hydralazine; Hypertension; Kidney; Male; Microscopy, Electron; Mineralocorticoid Receptor Antagonists; Nephritis; Oxidative Stress; Podocytes; Proteinuria; Rats; Rats, Inbred Dahl; Spironolactone; Time Factors

2006
Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:2

    Topics: Aldosterone; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Cells, Cultured; Cyclic N-Oxides; Enzyme Activation; Eplerenone; Hydralazine; Immediate-Early Proteins; Infusion Pumps; Kidney; Mineralocorticoid Receptor Antagonists; NADPH Oxidases; Nephrectomy; Oxidative Stress; Podocytes; Protein Serine-Threonine Kinases; Proteinuria; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Spin Labels; Spironolactone; Time Factors; Up-Regulation

2007
High-salt diet increases plasma adiponectin levels independent of blood pressure in hypertensive rats: the role of the renin-angiotensin-aldosterone system.
    Journal of hypertension, 2010, Volume: 28, Issue:1

    Topics: Adiponectin; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Clonidine; Eplerenone; Hydralazine; Hypertension; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sodium Chloride, Dietary; Spironolactone; Telmisartan

2010
Mineralocorticoid receptor activation contributes to salt-induced hypertension and renal injury in prepubertal Dahl salt-sensitive rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Volume: 25, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Cyclic N-Oxides; Deoxyguanosine; Eplerenone; Hydralazine; Hypertension; Kidney; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Inbred Dahl; Receptors, Mineralocorticoid; Renal Insufficiency; Sodium Chloride, Dietary; Spin Labels; Spironolactone

2010
Aldosterone/Mineralocorticoid receptor stimulation induces cellular senescence in the kidney.
    Endocrinology, 2011, Volume: 152, Issue:2

    Topics: Acetylglucosaminidase; Aldosterone; Animals; Blood Pressure; Blotting, Western; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Eplerenone; Humans; Hydralazine; Hypertension; Kidney; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sirtuin 1; Spironolactone; Tumor Suppressor Protein p53

2011
Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice.
    American journal of hypertension, 2012, Volume: 25, Issue:3

    Topics: Actins; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cellular Senescence; Eplerenone; Genes, p16; Genes, p53; Hydralazine; Hypertension; Imidazoles; Kidney; Mice; Mice, Inbred C57BL; p21-Activated Kinases; Sirtuin 1; Sodium Chloride; Spironolactone; Tetrazoles

2012
Regulation of myogenic tone and structure of parenchymal arterioles by hypertension and the mineralocorticoid receptor.
    American journal of physiology. Heart and circulatory physiology, 2015, Jul-01, Volume: 309, Issue:1

    Topics: Animals; Antihypertensive Agents; Arterioles; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cerebrovascular Circulation; Cerebrum; Compliance; Eplerenone; Hydralazine; Hydrochlorothiazide; Hypertension; Middle Cerebral Artery; Mineralocorticoid Receptor Antagonists; Muscle Tonus; Muscle, Smooth, Vascular; Nifedipine; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Mineralocorticoid; Reserpine; Spironolactone; Vascular Remodeling; Vascular Stiffness

2015
Mineralocorticoid receptor antagonism protects the aorta from vascular smooth muscle cell proliferation and collagen deposition in a rat model of adrenal aldosterone-producing adenoma.
    Journal of physiology and biochemistry, 2018, Volume: 74, Issue:1

    Topics: ACTH-Secreting Pituitary Adenoma; Aldosterone; Animals; Antihypertensive Agents; Aorta; Cell Proliferation; Collagen; Disease Models, Animal; Eplerenone; Hydralazine; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Proto-Oncogene Proteins c-mdm2; Random Allocation; Rats, Sprague-Dawley; Spironolactone; Transforming Growth Factor beta; Vascular Remodeling; Vasodilator Agents

2018