hydralazine and endothelin-1

hydralazine has been researched along with endothelin-1 in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (27.27)18.2507
2000's8 (72.73)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Filep, JG; Földes-Filep, E; Fournier, A; Skrobik, Y1
Filep, JG1
Benedetti, G; Benigni, A; Bruzzi, I; Corna, D; Noris, M; Remuzzi, G; Todeschini, M; Zoja, C1
Adachi, C; Naruse, K; Naruse, M; Seki, T; Takagi, S; Takano, K; Tanabe, A; Yoshimoto, T1
Jenkins, DG; McEniery, CM; Webb, DJ; Wilkinson, IB1
Harris, AL; Knowles, HJ; Mole, DR; Tian, YM1
Abe, Y; Fan, Y; Kimura, S; Kobori, H; Nishiyama, A; Rahman, M; Seth, DM; Shokoji, T; Yao, L; Zhang, GX1
Gabriëls, G; Grisk, O; Lother, U; Rettig, R1
Callera, GE; Carvalho, MH; Fortes, ZB; Montezano, AC; Mota, AL; Nigro, D; Tostes, RC; Zorn, TM1
Chang, NC; Chen, CC; Lee, TM; Lin, MS1
Agharazii, M; Bélanger, S; Larivière, R; Lebel, M; Lemieux, P; Therrien, F1

Trials

1 trial(s) available for hydralazine and endothelin-1

ArticleYear
Endogenous endothelin-1 limits exercise-induced vasodilation in hypertensive humans.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:2

    Topics: Adult; Antihypertensive Agents; Cross-Over Studies; Endothelin Receptor Antagonists; Endothelin-1; Forearm; Hand Strength; Humans; Hydralazine; Hypertension; Infusions, Intra-Arterial; Male; Middle Aged; Peptides, Cyclic; Regional Blood Flow; Single-Blind Method; Time Factors; Vasodilation

2002

Other Studies

10 other study(ies) available for hydralazine and endothelin-1

ArticleYear
Effects of calcium antagonists on endothelin-1-induced myocardial ischaemia and oedema in the rat.
    British journal of pharmacology, 1996, Volume: 118, Issue:4

    Topics: Albumins; Animals; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Edema; Electrocardiography; Endothelin-1; Endothelins; Heart Rate; Hydralazine; Male; Myocardial Ischemia; Nifedipine; Peptide Fragments; Rats; Rats, Wistar; Receptors, Endothelin; Vasodilator Agents; Verapamil

1996
Endogenous endothelin modulates blood pressure, plasma volume, and albumin escape after systemic nitric oxide blockade.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:1 Pt 1

    Topics: Analysis of Variance; Animals; Antihypertensive Agents; Azepines; Blood Pressure; Bosentan; Data Interpretation, Statistical; Endothelin Receptor Antagonists; Endothelin-1; Hydralazine; Indoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plasma Volume; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Serum Albumin; Sulfonamides; Time Factors; Vasodilator Agents

1997
Renoprotection by nitric oxide donor and lisinopril in the remnant kidney model.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1999, Volume: 33, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Creatinine; Disease Progression; Eating; Endothelin-1; Hydralazine; Hydrochlorothiazide; Kidney; Lisinopril; Male; Molsidomine; Nephrectomy; Nitric Oxide; Nitric Oxide Donors; Nitrous Oxide; Rats; Rats, Sprague-Dawley; Reserpine

1999
Hydralazine decreases blood pressure and endothelin-1 mRNA expression in tissues but not cardiac weight in SHR-SP/Izm rats.
    Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:5 Suppl 1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Cardiomegaly; Endothelin-1; Hydralazine; Male; Organ Size; Rats; Rats, Inbred SHR; RNA, Messenger

2000
Novel mechanism of action for hydralazine: induction of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases.
    Circulation research, 2004, Jul-23, Volume: 95, Issue:2

    Topics: Adrenomedullin; Angiogenesis Inducing Agents; Animals; Breast Neoplasms; Carcinoma; Carcinoma, Renal Cell; Cell Hypoxia; Cell Line, Tumor; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endothelial Cells; Endothelin-1; Enzyme Inhibitors; Gene Expression Regulation; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Hydralazine; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Implants, Experimental; Kidney Neoplasms; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Myocytes, Smooth Muscle; Neovascularization, Physiologic; Nuclear Proteins; Peptides; Procollagen-Proline Dioxygenase; Transcription Factors; Vascular Endothelial Growth Factor A; Vasodilator Agents

2004
Olmesartan improves endothelin-induced hypertension and oxidative stress in rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2004, Volume: 27, Issue:7

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Endothelin-1; Hydralazine; Hypertension; Imidazoles; Male; Olmesartan Medoxomil; Oxidative Stress; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Superoxides; Tetrazoles; Thiobarbituric Acid Reactive Substances

2004
Influence of neonatal sympathectomy on proximal renal resistance artery function in spontaneously hypertensive rats.
    Pflugers Archiv : European journal of physiology, 2005, Volume: 449, Issue:4

    Topics: Animals; Animals, Newborn; Antihypertensive Agents; Blood Pressure; Calcium; Calcium Channels, L-Type; Catecholamines; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Hydralazine; Kidney Tubules, Proximal; Muscle Relaxation; Muscle, Smooth, Vascular; Myography; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Renal Artery; Sympathectomy, Chemical; Vascular Resistance; Vasodilation

2005
Endothelin-1 contributes to the sexual differences in renal damage in DOCA-salt rats.
    Peptides, 2005, Volume: 26, Issue:8

    Topics: Animals; Dansyl Compounds; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Estrogens; Female; Hydralazine; Hypertension; Kidney; Kidney Diseases; Male; Ovariectomy; Progesterone; Rats; Rats, Wistar; Receptor, Endothelin A; RNA, Messenger; Sex Characteristics; Sodium Chloride

2005
Effect of endothelin receptor antagonists on ventricular susceptibility in postinfarcted rats.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Atrasentan; Blotting, Western; Bosentan; Cardiac Pacing, Artificial; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; GAP-43 Protein; Hemodynamics; Hydralazine; Immunohistochemistry; Male; Methoxyhydroxyphenylglycol; Myocardial Infarction; Myocardium; Nerve Growth Factor; Neurofilament Proteins; Norepinephrine; Polymerase Chain Reaction; Pyrrolidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Sulfonamides; Sympathetic Nervous System; Time Factors; Tyrosine 3-Monooxygenase; Up-Regulation

2008
Protective effects of angiotensin AT1 receptor blockade in malignant hypertension in the rat.
    European journal of pharmacology, 2009, Apr-01, Volume: 607, Issue:1-3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atrasentan; Blood Pressure; Endothelin-1; Hydralazine; Hypertension, Malignant; Losartan; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renal Insufficiency

2009