hydralazine has been researched along with dihydralazine in 158 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 145 (91.77) | 18.7374 |
1990's | 8 (5.06) | 18.2507 |
2000's | 2 (1.27) | 29.6817 |
2010's | 2 (1.27) | 24.3611 |
2020's | 1 (0.63) | 2.80 |
Authors | Studies |
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Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Chen, Z; Ding, H; Du, D; Liu, J; Luo, C; Sun, Z; Wang, M; Wu, Q | 1 |
Herold, M; Jung, N; Lauten, A | 1 |
Schrey, A | 1 |
Alison, D; Latour, F; Lavigne, G; Masson, D; Morand, P | 1 |
Halawa, B | 1 |
Besse, P; Larnaudie, B; Page, A; Pic, A; Videau, P | 1 |
Corvol, P; Gouin, F; Menard, J; Milliez, P; Plouin, PF | 1 |
Asboe-Hansen, G; Blumenkrantz, N; Christiansen, AH | 1 |
Aurell, M; Granerus, G; Herlitz, H | 1 |
Lammintausta, R | 1 |
Allonen, H; Kleimola, T; Lehtonen, A | 1 |
Iisalo, E; Laine, T; Lehtonen, A; Sellman, R | 1 |
Imhof, P; Pfister, B | 1 |
Subramanyam, S | 1 |
Denoroy, L; Renaud, B; Sacquet, J; Sassard, J; Vincent, M | 1 |
Andersson, KE; Mikkelsen, E; Pedersen, OL | 1 |
Gerold, M; Haeusler, G | 1 |
Fakri, E; François, B | 1 |
Brion, NO; Colau, C; Godeau, P; Wechsler, B; Ximenes, H | 1 |
Chasseaud, LF; Taylor, T; Waller, AR | 1 |
Chodakowska, J; Cybulska, I; Raczyński, J | 1 |
Cartheuser, CF; Komarek, J | 1 |
Ambrosio, G; Corgnati, A; Dal Palù, C; Palatini, P; Pessina, AC | 1 |
Börner, H; Teichmann, G | 1 |
Falch, DK; Norman, N | 1 |
Ebel, H; Klaus, D; Lübke, H; Witzgall, H; Zehner, J | 1 |
Dunemann, A; Förster, W; Hauser, A; Taube, C | 1 |
Latour, F; Lavigne, G; Masson, D; Morand, P | 1 |
Elshabouri, SR; Ibrahim, SA; Youssef, AF | 1 |
Cueni, B; Knoblauch, M; Schmid, M; Spycher, M | 1 |
Barzilai, D; Enat, R; Rader, G | 1 |
Cieszyński, T | 1 |
Angelino, PF | 1 |
Berezhnitskiĭ, MN; Mikhal'chuk, BD | 1 |
Boeryd, B; Hagmar, B; Johnsson, G; Ryd, W | 1 |
Rettske, U; Shvarts, R | 1 |
Hennig, D | 1 |
Nässberger, L | 1 |
Hof, A; Hof, RP; Takiguchi, Y | 1 |
Andersson, M; Dahlbäck, B; Englund, G; Hanson, A | 1 |
Berchel, C; Breart, G; Dalle, M; Goujon, H; Keller, ME; Llado, J; Plouin, PF | 1 |
Gerzer, R; Heim, JM; Müller, T; Wehling, M; Weil, J; Witzgall, H | 1 |
Mohácsi, G; Sonkodi, S | 1 |
Gerzer, R; Heim, JM; Lorenz, R; Müller, T; Wehling, M; Weil, J; Witzgall, H | 1 |
Baumgarten, R; Fengler, JD; Franke, G; Krüger, R; Reichardt, R; Siegmund, W | 1 |
Beyrich, T; Feldmeier, HG; Herberg, H | 1 |
Henschel, L; Hoffmann, A; Jorke, D; Rechenbach, C; Reinhardt, M | 1 |
Belfort, M; Davey, DA; Dommisse, J; Uys, P | 1 |
Azizi, M; Levy, B; Ménard, J; Michel, JB; Salzmann, JL | 1 |
Eggertsen, R; Hansson, L | 1 |
Glatt, H; Oesch, F | 1 |
Dimitrov, G; Kaponov, Kh; Penkov, N; Sirakova, V | 1 |
Evenou, JP; Hof, RP; Hof-Miyashita, A | 1 |
Auzan, C; Choudat, L; Corvol, P; Dussaule, JC; Menard, J; Michel, JB; Nochy, D | 1 |
Antalóczy, Z; Bányai, F; Dékány, M | 1 |
Schroeder, T; Sillesen, H | 1 |
Colombel, JF; Cortot, A; Dessaint, JP; Gerard, A; Houcke, M; Paris, JC; Prin, L | 1 |
Kallwellis, R; Schneider, T; Siegmund, W; Zschiesche, M | 1 |
Lunell, NO; Nylund, L | 1 |
Hass, S; Roschlau, G; Schmehl, V | 1 |
Kallwellis, R; Scherber, A; Schneider, T; Siegmund, W; Zschiesche, M | 1 |
Franke, G; Hüller, H; Schröder, L; Siegmund, W; Zschiesche, M | 1 |
Bourreli, B; Drouet, JC; Gunst, JP; Passuti, N; Pinaud, M; Remi, JP | 1 |
Bergert, A; Justus, J; Kunze, P; Machnik, G; Müller, R; Reinhardt, M; Schulz, H; Stein, G; Thiele, R | 1 |
Franke, G; Hüller, H; Schröder, L; Siegmund, W; Udvary, E; Zschiesche, M | 1 |
Dahlerup, B; Laursen, J | 1 |
Bartels, T; Beitz, J; Heinemann, S; Hoffmann, P; Taube, C | 1 |
Aurell, M; Delin, K; Granerus, G; Hedner, T; Herlitz, H | 1 |
Ashe, RG; Moodley, J; Philpott, RH; Richards, AM | 1 |
Biebler, KE; Donner, I; Franke, G; Kairies, M; Siegmund, W | 1 |
Moodley, J; Vasant, RV | 1 |
Benndorf, S; Kehrbein, C; Nahrendorf, W; Rading, A; Steinig, G; Weidler, B | 1 |
Olkkonen, H; Pääkkönen, A; Saarikoski, S; Suonio, S; Tahvanainen, K | 1 |
Magnusson, H; Pontén, J; Sonander, HG | 1 |
Grisk, A; Lohberg, S; Schneider, T; Schröder, LW; Siegmund, W | 1 |
Cernohorský, D; Eliás, J; Hamet, A; Koudelka, V; Král, B; Rozánek, P; Sramar, V; Tilser, P | 1 |
Frídl, P; Jandová, R; Jebavý, P; Koudelková, E | 1 |
Franke, G; Kraatz, G; Scherber, A; Schneider, T; Siegmund, W | 1 |
Jouppila, P; Kirkinen, P; Koivula, A; Ylikorkala, O | 1 |
Kunze, KD; Porst, H; Tschöpel, L | 1 |
Biebler, KE; Donner, I; Franke, G; Hüller, H; Kairies, M; Kallwellis, R; Scherber, A; Siegmund, W | 1 |
Bachmann, R; Belz, G; Belz, GG; Graf, D; Matthews, JH; Palm, D; Steinijans, VW; Stern, HC | 1 |
Franke, G; Grabow, D; Pietsch, P; Schneider, T; Schütz, H; Siegmund, W | 1 |
Kunze, KD; Lohmann, J; Porst, H; Tschöpel, L | 1 |
Kantola, I; Leino, R; Seppälä, P; Viikari, J | 1 |
Baudouy, M; Camous, JP; Gibelin, P; Leborgne, L; Morand, P | 1 |
Fontaine, JL; Girardet, JP | 1 |
Fontaine, JL; Girardet, JP; Liechtmaneger, H; Verlhac, S | 1 |
Campestrini, J; Rouan, MC | 1 |
Jahn, G; Krombholz, B; Machnik, G; Reinhardt, M | 1 |
Franke, G; Hüller, H; Kallwellis, R; Scherber, A; Schneider, T; Siegmund, W; Sill, U; Zschiesche, M | 1 |
Alhenc-Gélas, F; Auzan, C; Corvol, P; Dussaule, JC; Ménard, J; Michel, JB | 1 |
Henning, M; Persson, B; Svensson, TH | 1 |
Bartsch, W; Glocke, M; Häcker, W; Teufel, W | 1 |
Holzgreve, H | 1 |
Plouin, PF | 1 |
Freslon, JL; Giudicelli, JF | 1 |
Bacher, S; Beck, A; Kraupp, O; Raberger, G; Seitelberger, R | 1 |
Dziamski, R; Głuszek, J; Krug, H; Piszczek, I | 1 |
Bertel, O | 1 |
Köhler, W; Schmidt, H; von Jan, V | 1 |
Belz, GG; Matthews, JH; Stern, HC | 1 |
Bussmann, WD; Kaltenbach, M; Reifart, N | 1 |
Beckett, AH; Frohn, MJ; Jones, GR | 1 |
Auer, LM; Johansson, BB; Sayama, I | 1 |
Overgaard, J; Skinhøj, E | 1 |
Lewander, R; Lunell, NO; Nylund, L; Sarby, B; Thornström, S | 1 |
Ambrosioni, E; Caldari, R; Costa, FV; Malini, PL; Marata, AM; Parini, J; Strocchi, E | 1 |
Smits, JF; Struyker-Boudier, HA; van Essen, H | 1 |
Diuk, KD | 1 |
Jounela, AJ; Karppanen, H; Salmela, PI | 1 |
Huse, K; Röhner, G | 1 |
Csongrady, A; Ponz-Gonzalez, L | 1 |
Baclet, M; Fernandez, F; Gerbaux, A; Lelguen, C; Sprogis, W | 1 |
Brinkmann, HM; Dressler, P; Fleischer, F; Krier, C; Späth, J | 1 |
Bunge, T; Bussmann, WD; Kaltenbach, M; Reifart, N | 1 |
Achimastos, A; Levenson, J; Safar, M; Simon, A; Temmar, M | 1 |
Benetos, AM; Bouthier, JE; Levenson, JA; Safar, ME; Simon, AC | 1 |
Roschlau, G | 1 |
Benhamou, JP; Bernuau, J; Degott, C; Pariente, EA; Pessayre, D | 1 |
Beck, D; Bönner, G; Deeg, M; Gross, F; Marin-Grez, M | 1 |
Förster, W; Hoffmann, P; Taube, C | 1 |
Corvol, P; Lardoux, MD; Thibonnier, M | 1 |
Gerc, V; Numić, N | 1 |
Criscuolo, D; Piazza, W; Salvadeo, A; Segagni, S; Villa, G | 1 |
Bagatin, J; Jurisić, M; Rumboldt, Z | 1 |
Brandstetter, G; Gasser, RW; Skrabal, F | 1 |
Moodley, J; Vink, GJ | 1 |
Davey, DA; Dommisse, J; Garden, A | 1 |
Bennicelli, C; Brambilla, G; Cajelli, E; Camoirano, A; Cavanna, M; de Flora, S; Faggin, P; Sciabà, L; Zanacchi, P | 1 |
Bernard, K | 1 |
Brechbühler, S; Degen, PH; Schneider, W; Zbinden, P | 1 |
Arbeille-Brassart, B; Freslon, JL; Giudicelli, JF | 1 |
Frölich, JC; Ratge, D; Reimann, IW; Wisser, H | 1 |
Kendrey, G; László, B | 2 |
Falch, DK; Norman, N; Sundsfjord, JA | 1 |
Moodley, J; Philpott, RH; Vink, GJ | 1 |
Francoual, M; Nitenberg, A | 1 |
Mölleken, K; Rüger, K | 1 |
Mazue, G; McQueen, CA; Shimada, T; Williams, GM | 1 |
Panikarskiĭ, VG | 1 |
Himmler, FC; Klein, G; Kutschera, I; Sauer, E; Schmidt, G; Wirtzfeld, A | 1 |
Gasiorowski, K; Gulanowski, B; Sawicka, J; Szyba, K | 1 |
Hansson, AL; Nässberger, L | 1 |
Chłopkiewicz, B | 2 |
KIRPEKAR, SM; LEWIS, JJ | 1 |
SINGH, I | 1 |
ABLAD, B | 1 |
GOEMOERI, P; KALLAY, K; NAGY, Z; SZABO, Z | 1 |
Gajewska, M; Iliaszenko, J; Sokołowska-Muszyńska, M | 1 |
3 review(s) available for hydralazine and dihydralazine
Article | Year |
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[Use of vasodilator agents in circulatory insufficienty].
Topics: Blood Circulation; Dihydralazine; Heart Failure; Humans; Hydralazine; Nitrates; Nitroglycerin; Nitroprusside; Prazosin; Quinazolines; Vasodilator Agents | 1979 |
Vasodilators in hypertension--a review with special emphasis on the combined use of vasodilators and beta-adrenoceptor blockers.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Carbazoles; Carvedilol; Diazoxide; Dihydralazine; Drug Therapy, Combination; Glomerular Filtration Rate; Guanidines; Humans; Hydralazine; Hypertension; Minoxidil; Pinacidil; Plasma Volume; Propanolamines; Pyridazines; Renin-Angiotensin System; Serotonin Antagonists; Vascular Resistance; Vasodilator Agents | 1985 |
[Vasodilator agents in the treatment of cardiac insufficiency].
Topics: Captopril; Dihydralazine; Heart Failure; Humans; Hydralazine; Nitroglycerin; Nitroprusside; Phentolamine; Prazosin; Vasodilator Agents | 1984 |
27 trial(s) available for hydralazine and dihydralazine
Article | Year |
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[An example of an acceptable combination in the treatment of arterial hypertension].
Topics: Adult; Aged; Clinical Trials as Topic; Dihydralazine; Double-Blind Method; Drug Combinations; Drug Evaluation; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Oxprenolol; Placebos | 1978 |
The renin-aldosterone system in dihydralazine therapy during hypertensive pregnancy.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Dihydralazine; Electrolytes; Female; Heart Rate; Humans; Hydralazine; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Renin; Time Factors | 1978 |
Antihypertensive effect and plasma levels of labetalol. A comparison with propranolol and dihydrallazine.
Topics: Adult; Dihydralazine; Drug Therapy, Combination; Ethanolamines; Female; Heart Rate; Humans; Hydralazine; Hypertension; Labetalol; Male; Middle Aged; Placebos; Propranolol; Time Factors | 1979 |
[Treatment of essential hypertension with a combination of propranolol, spironolactone-thiabutazide and dihydralazine (author's transl)].
Topics: Anxiety; Bradycardia; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Paresthesia; Potassium; Propranolol; Renin; Spironolactone | 1978 |
A randomized comparison of early with conservative use of antihypertensive drugs in the management of pregnancy-induced hypertension.
Topics: Adult; Birth Weight; Cesarean Section; Dihydralazine; Double-Blind Method; Drug Therapy, Combination; Female; Fetal Death; Gestational Age; Humans; Hydralazine; Hypertension; Infant, Newborn; Labor, Obstetric; Length of Stay; Oxprenolol; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Randomized Controlled Trials as Topic | 1990 |
Haemodynamic changes in gestational proteinuric hypertension: the effects of rapid volume expansion and vasodilator therapy.
Topics: Adult; Cardiac Output; Catheterization, Swan-Ganz; Dihydralazine; Female; Fluid Therapy; Hemodynamics; Humans; Hydralazine; Magnesium Sulfate; Plasma Substitutes; Polygeline; Pre-Eclampsia; Pregnancy; Pulmonary Wedge Pressure; Random Allocation; Vasodilator Agents | 1989 |
Comparative study on the short-term effects of angiotensin converting enzyme inhibitors (Lopirin, SQUIBB and Tensiomin), and dihydralazine in chronic cardiac failure.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cardiac Output, Low; Chronic Disease; Clinical Trials as Topic; Dihydralazine; Female; Humans; Hydralazine; Male; Middle Aged; Stroke Volume; Time Factors | 1988 |
Comparison of labetalol and dihydralazine in hypertensive emergencies of pregnancy.
Topics: Blood Pressure; Clinical Trials as Topic; Dihydralazine; Female; Heart Rate; Heart Rate, Fetal; Humans; Hydralazine; Hypertension; Labetalol; Platelet Count; Pregnancy; Pregnancy Complications, Cardiovascular; Random Allocation; Time Factors | 1987 |
Methohexitone anaesthesia for microlaryngoscopy: circulatory modulation with metoprolol and dihydralazine.
Topics: Aged; Anesthesia, Intravenous; Arrhythmias, Cardiac; Blood Pressure; Dihydralazine; Female; Heart Rate; Humans; Hydralazine; Intraoperative Complications; Laryngoscopy; Male; Methohexital; Metoprolol; Middle Aged; Premedication | 1986 |
Dynamic responses to intravenous urapidil and dihydralazine in normal subjects.
Topics: Adult; Blood Pressure; Cardiography, Impedance; Clinical Trials as Topic; Dihydralazine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Hydralazine; Male; Piperazines; Random Allocation; Systole; Vascular Resistance | 1985 |
[Therapeutic equivalent of a single and divided daily dose of 2 Tri-Torrat coated tablets].
Topics: Clinical Trials as Topic; Dihydralazine; Double-Blind Method; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Metipranolol; Middle Aged; Propanolamines; Tablets, Enteric-Coated | 1984 |
Cerebral symptoms and blood pressure during parenteral administration of chlorpromazine, dihydralazine and diazoxide. Danish multicenter study on acute severe hypertension.
Topics: Blood Pressure; Brain Diseases; Brain Ischemia; Chlorpromazine; Clinical Trials as Topic; Diazoxide; Dihydralazine; Emergencies; Furosemide; Humans; Hydralazine; Hypertension; Hypotension; Paralysis; Risk | 1983 |
[Dihydralazine in the treatment of bradycardia in the sick sinus syndrome].
Topics: Adult; Aged; Bradycardia; Clinical Trials as Topic; Dihydralazine; Female; Heart Rate; Humans; Hydralazine; Male; Middle Aged; Sick Sinus Syndrome | 1984 |
Loss of effectiveness of dihydralazine in the long-term treatment of chronic heart failure.
Topics: Adult; Aged; Cardiac Output; Chronic Disease; Coronary Circulation; Coronary Disease; Dihydralazine; Female; Heart Failure; Humans; Hydralazine; Male; Middle Aged; Physical Exertion; Stroke Volume; Time Factors; Vascular Resistance | 1984 |
Comparison of the antihypertensive activity of cadralazine (ISF 2469) and dihydralazine during chronic treatment.
Topics: Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Dihydralazine; Female; Headache; Heart Rate; Humans; Hydralazine; Hypertension; Male; Middle Aged; Nausea; Pyridazines; Random Allocation; Water-Electrolyte Imbalance | 1983 |
Double-blind comparison of dihydralazine and prazosin in hypertensive patients on the diuretic-reserpine regimen.
Topics: Adult; Aged; Clinical Trials as Topic; Dihydralazine; Double-Blind Method; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Norepinephrine; Prazosin; Quinazolines; Renin; Reserpine; Triamterene | 1981 |
[Circulatory effects of dihydrazinophthalazine (Nepresol) compared with sodium nitroprusside in controlled hypotension. A study of neurosurgical patients under neuroleptanesthesia].
Topics: Adult; Aged; Blood Pressure; Carbon Dioxide; Cardiac Output; Dihydralazine; Dose-Response Relationship, Drug; Ferricyanides; Heart Rate; Hemodynamics; Humans; Hydralazine; Hypotension, Controlled; Middle Aged; Neuroleptanalgesia; Neurosurgical Procedures; Nitroprusside; Oxygen; Oxygen Consumption; Stroke Volume | 1980 |
[Combined use of dihydralazine and nitroglycerin during and after cardiac surgery (author's transl)].
Topics: Adult; Cardiac Output; Cardiac Surgical Procedures; Dihydralazine; Female; Humans; Hydralazine; Intraoperative Care; Male; Middle Aged; Nitroglycerin; Postoperative Care; Stroke Volume | 1982 |
Comparative trial of labetalol and acebutolol, alone or associated with dihydralazine, in treatment of essential hypertension.
Topics: Acebutolol; Adult; Clinical Trials as Topic; Dihydralazine; Drug Therapy, Combination; Ethanolamines; Female; Humans; Hydralazine; Hypertension; Labetalol; Male; Middle Aged; Renin | 1980 |
[Use of oxprenolol, triamterene, and dihydralazine in the treatment of essential hypertension].
Topics: Adult; Aged; Clinical Trials as Topic; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Oxprenolol; Triamterene | 1980 |
Comparative study of oxdralazine and dihydralazine in essential hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Dihydralazine; Ethanolamines; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Pyridazines | 1981 |
[A cross-over comparison of dihydralazine and minoxidil in severe hypertension (author's transl)].
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dihydralazine; Humans; Hydralazine; Hypertension; Male; Middle Aged; Minoxidil; Pyrimidines | 1982 |
[Treatment of hypertension with a drug combination, consisting of bemetizide, triamterene, dihydralazine and bupranolol (author's transl)].
Topics: Adult; Benzothiadiazines; Bupranolol; Dihydralazine; Drug Combinations; Humans; Hydralazine; Hypertension; Middle Aged; Propanolamines; Pulse; Triamterene | 1982 |
Intravenous labetalol and intravenous dihydralazine in severe hypertension in pregnancy.
Topics: Adult; Blood Pressure; Dihydralazine; Eclampsia; Ethanolamines; Female; Fetus; Humans; Hydralazine; Infant, Newborn; Infusions, Parenteral; Labetalol; Pre-Eclampsia; Pregnancy; Random Allocation | 1982 |
Are prostaglandins involved in the antihypertensive effect of dihydralazine?
Topics: Adult; Diclofenac; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Prostaglandins | 1981 |
[Orally active vasodilators in the management of chronic treatment-resistant cardiac failure (author's transl)].
Topics: Adult; Aged; Dihydralazine; Heart Failure; Hemodynamics; Humans; Hydralazine; Isosorbide Dinitrate; Middle Aged; Prazosin; Quinazolines | 1980 |
Emergency treatment of severe hypertension evaluated in a randomized study. Effect of rest and furosemide and a randomized evaluation of chlorpromazine, dihydralazine and diazoxide. Danish Multicenter Study.
Topics: Adult; Aged; Chlorpromazine; Denmark; Diazoxide; Dihydralazine; Drug Administration Schedule; Female; Furosemide; Humans; Hydralazine; Hypertension; Male; Middle Aged; Posture; Prospective Studies; Random Allocation | 1980 |
128 other study(ies) available for hydralazine and dihydralazine
Article | Year |
---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
The discovery of a non-competitive GOT1 inhibitor, hydralazine hydrochloride, via a coupling reaction-based high-throughput screening assay.
Topics: Aspartate Aminotransferase, Cytoplasmic; Cell Line, Tumor; Cell Proliferation; High-Throughput Screening Assays; Hydralazine | 2022 |
[The treatment of critical hypertension with depressan and obsidan infusions].
Topics: Adrenergic beta-Antagonists; Cardiac Output; Dihydralazine; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Propranolol | 1979 |
[New nitrate indications].
Topics: Dihydralazine; Drug Combinations; Heart Diseases; Humans; Hydralazine; Isosorbide Dinitrate; Myocardial Infarction; Nitrates; Nitroglycerin; Nitroprusside; Phentolamine; Vasodilator Agents | 1978 |
[Treatment of severe chronic cardiac insufficiency with dihydralazine. Short-and median-term results].
Topics: Administration, Oral; Adult; Aged; Chronic Disease; Dihydralazine; Drug Evaluation; Female; Heart Failure; Humans; Hydralazine; Male; Middle Aged | 1979 |
[Hemodynamic effects of oral dihydralazine and sublingual isosorbide dinitrate, alone and in combination in chronic heart failure].
Topics: Administration, Oral; Aged; Chronic Disease; Dihydralazine; Drug Therapy, Combination; Female; Heart Failure; Hemodynamics; Humans; Hydralazine; Isosorbide Dinitrate; Male; Middle Aged; Mouth Floor | 1979 |
Effect of hydralazine and dihydralazine on connective tissue and binding to serum protein.
Topics: Animals; Autoradiography; Blood Proteins; Chick Embryo; Collagen; Connective Tissue; Dihydralazine; Hydralazine; Immunodiffusion; Macromolecular Substances; Organ Culture Techniques; Procollagen; Procollagen-Proline Dioxygenase; Protein Binding; Rats; Skin; Tibia | 1979 |
Cyclic AMP, renal function and dihydralazine-stimulated renin secretion in hypertensive patients.
Topics: Aged; Cyclic AMP; Dihydralazine; Female; Glomerular Filtration Rate; Humans; Hydralazine; Hypertension, Renal; Hypertension, Renovascular; Kidney; Male; Middle Aged; p-Aminohippuric Acid; Renin; Sympathetic Nervous System | 1979 |
Dihydralazine therapy and acetylator phenotype.
Topics: Acetylation; Adult; Aged; Creatinine; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Phenotype | 1979 |
Influence of vasodilators used in the therapy of heart failure on platelet aggregation.
Topics: Dihydralazine; Heart Failure; Humans; Hydralazine; In Vitro Techniques; Phentolamine; Platelet Aggregation; Prazosin; Time Factors; Vasodilator Agents | 1979 |
Cytogenetic action of the antihypertensive agent adelphane on meiotic cells of Poekilocerus pictus.
Topics: Animals; Antihypertensive Agents; Chromatids; Chromosome Aberrations; Dihydralazine; Drug Combinations; Grasshoppers; Hydralazine; Male; Meiosis; Mutagens; Reserpine; Spermatogonia | 1979 |
Dihydralazine and catecholamine-synthesizing enzymes in spontaneous hypertension.
Topics: Adrenal Medulla; Animals; Blood Pressure; Catecholamines; Dihydralazine; Ganglia, Sympathetic; Hydralazine; Hypertension; Male; Medulla Oblongata; Rats; Time Factors | 1979 |
Comparison of the in vitro effects of prazosin, nifedipine, and dihydralazine in isolated human mesenteric and crural vessels.
Topics: Adolescent; Adult; Aged; Calcium; Dihydralazine; Humans; Hydralazine; In Vitro Techniques; Leg; Mesenteric Arteries; Mesenteric Veins; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium; Prazosin; Pyridines; Quinazolines | 1979 |
Increased levels of prostaglandin-like material in the canine blood during arterial hypotension produced by hydralazine, dihydralazine and minoxidil.
Topics: Angiotensin II; Animals; Blood Pressure; Dihydralazine; Dogs; Female; Guinea Pigs; Hydralazine; Hypotension; Indomethacin; Male; Minoxidil; Prostaglandins; Pyrimidines; Rabbits; Species Specificity; Time Factors | 1979 |
[Can lupus be caused by dihydralazine?].
Topics: Adult; Aged; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Male; Middle Aged | 1979 |
[Lupus erythematosus induced by dihydralazine].
Topics: Dihydralazine; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Middle Aged | 1979 |
High-performance liquid chromatographic determination of dihydralazine in human plasma.
Topics: Chromatography, High Pressure Liquid; Dihydralazine; Humans; Hydralazine; Male; Mass Spectrometry | 1979 |
[Simultaneous administration of dihydralazine, propranolol and a diuretic in the treatment of severe hypertension].
Topics: Adolescent; Adult; Dihydralazine; Diuretics; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Propranolol | 1977 |
[Dihydralazin versus prazosin. The hemodynamic effect of the modul substances (author's transl)].
Topics: Animals; Blood Pressure; Cardiac Output; Cardiovascular System; Dihydralazine; Dogs; Heart Rate; Heart Ventricles; Hydralazine; Myocardial Contraction; Prazosin; Quinazolines; Stimulation, Chemical; Time Factors; Vascular Resistance | 1977 |
[Long-term treatment of arterial hypertension with propranolol. Combination with diuretics and dihydrazinophthalazine].
Topics: Adult; Dihydralazine; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Male; Middle Aged; Propranolol; Time Factors | 1978 |
[Hemodynamic parameters and plasma-renin activity following intravenous dihydralazine administration--a contribution to the regulation of renin].
Topics: Adolescent; Adult; Arterial Occlusive Diseases; Dihydralazine; Female; Glomerulonephritis; Humans; Hydralazine; Hypertension; Injections, Intravenous; Male; Middle Aged; Renal Artery; Renin | 1978 |
The cardiac response to a small i.v. dose of dihydralazine, a safe drug for diagnostic tests?
Topics: Adult; Blood Pressure; Cardiac Output; Coronary Vessels; Dihydralazine; Dose-Response Relationship, Drug; Female; Heart; Heart Rate; Hemodynamics; Humans; Hydralazine; Hypertension, Renal; Injections, Intravenous; Kidney; Male; Middle Aged; Radioisotope Renography; Regional Blood Flow; Vascular Resistance | 1978 |
Changes of prostaglandin synthesis in aorta, brain and kidney medulla of normal rats treated with antihypertensive drugs.
Topics: Animals; Aorta; Blood Pressure; Brain; Clonidine; Dihydralazine; Hydralazine; Kidney Medulla; Methyldopa; Prostaglandins; Rats; Reserpine | 1978 |
[The treatment of severe chronic cardiac failure by dihydralazine].
Topics: Adult; Aged; Chronic Disease; Dihydralazine; Heart Diseases; Humans; Hydralazine; Male; Middle Aged | 1978 |
Dihydralazine sulfate analysis using 2-methyl-o-nitropyridine-6-carboxaldehyde.
Topics: Aldehydes; Colorimetry; Dihydralazine; Drug Combinations; Hydralazine; Tablets; Time Factors | 1977 |
[Dihydralazine-induced hepatitis].
Topics: Chemical and Drug Induced Liver Injury; Dihydralazine; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic | 1977 |
[Dihydralazine-induced acute hepatitis with IgM deficiency].
Topics: Acetylation; Aged; Antibodies; Chemical and Drug Induced Liver Injury; Dihydralazine; Drug Hypersensitivity; Female; Humans; Hydralazine; Hyperbilirubinemia; Hypertension; Immunoglobulin M; Liver; Male; Middle Aged; Mitochondria; Phenotype | 1977 |
[Liver damage caused by adelphan].
Topics: Aged; Aspartate Aminotransferases; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Jaundice; Liver | 1977 |
[Identification of binazine and dihydralazine by new color reactions].
Topics: Color; Dihydralazine; Hydralazine; Hydrazines; Indicators and Reagents; Todralazine | 1977 |
[Therapeutic combinations, side effects and interactions of antihypertensive drugs].
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Dihydralazine; Diuretics; Drug Interactions; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Propranolol; Reserpine; Spironolactone | 1976 |
[Evaluation of the therapeutic effect of dopegit and depressin in hypertension according to polycardiographic data].
Topics: Adult; Aged; Antihypertensive Agents; Depression, Chemical; Dihydralazine; Drug Evaluation; Female; Heart Function Tests; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; Myocardial Contraction | 1976 |
Alteration of metastases distribution by vaso-dilating drugs.
Topics: Animals; Dihydralazine; Hydralazine; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Inbred CBA; Neoplasm Metastasis; Phenoxybenzamine; Sarcoma, Experimental; Vasomotor System | 1975 |
[Reduction of the arterial pressure with the help of dihydralazin in late toxemia of pregnancy].
Topics: Blood Pressure; Dihydralazine; Female; Humans; Hydralazine; Pre-Eclampsia; Pregnancy | 1975 |
[Clinical experience with intravenous depressan ampules].
Topics: Adult; Aged; Antihypertensive Agents; Dihydralazine; Humans; Hydralazine; Hypertension; Injections, Intravenous; Middle Aged; Sulfonic Acids | 1975 |
The antihypertensive compounds hydralazine, dihydralazine and cadralazine and their metabolites inhibit myeloperoxidase activity as measured by chemiluminescence.
Topics: Antihypertensive Agents; Binding Sites; Dihydralazine; Dose-Response Relationship, Drug; Hydralazine; Luminescent Measurements; Magnetic Resonance Spectroscopy; Peroxidase; Pyridazines; Structure-Activity Relationship | 1991 |
Comparative hemodynamic studies of isradipine and dihydralazine in atherosclerotic and normal rabbits.
Topics: Animals; Arteriosclerosis; Calcium Channel Blockers; Coronary Artery Disease; Dihydralazine; Electrocardiography; Hemodynamics; Hydralazine; Isradipine; Microspheres; Pyridines; Rabbits; Regional Blood Flow | 1990 |
Inhibition of complement components C3 and C4 by cadralazine and its active metabolite.
Topics: Antihypertensive Agents; Complement C3; Complement C4; Dihydralazine; Humans; Hydralazine; Hydroxylamine; Hydroxylamines; Procainamide; Pyridazines; Vasodilator Agents | 1991 |
Effects of clonidine and dihydralazine on plasma ANF and cyclic GMP levels in humans during volume loading.
Topics: Adult; Atrial Natriuretic Factor; Blood Pressure; Clonidine; Cyclic GMP; Dihydralazine; Heart Rate; Hematocrit; Humans; Hydralazine; Infusions, Intravenous; Isotonic Solutions; Male; Potassium; Sodium; Sodium Chloride | 1987 |
Comparison of BAY e 5009 (nitrendipine) with dihydralazine in Wistar rats with experimentally induced nephritis.
Topics: Animals; Antibodies; Basement Membrane; Blood Pressure; Dihydralazine; Glomerulonephritis; Hydralazine; Male; Nitrendipine; Proteinuria; Rats; Rats, Inbred Strains; Time Factors | 1988 |
Effects of clonidine and dihydralazine on atrial natriuretic factor and cGMP in humans.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Clonidine; Cyclic GMP; Dihydralazine; Diuresis; Hemodynamics; Humans; Hydralazine; Male; Natriuresis; Renin | 1989 |
Kinetics of antipyrine and sulfamethazine in patients recovered from dihydralazine-hepatitis.
Topics: Acetylation; Adult; Aged; Antipyrine; Chemical and Drug Induced Liver Injury; Dihydralazine; Female; Humans; Hydralazine; Male; Middle Aged; Oxidation-Reduction; Sulfamethazine | 1989 |
[Spectrophotometric analysis of the multicomponent system: dihydralazine sulfate, hydrochlorothiazide and reserpine].
Topics: Dihydralazine; Hydralazine; Hydrochlorothiazide; Reserpine; Spectrophotometry, Ultraviolet | 1989 |
[Biotransformation in patients following Depressan-induced hepatitis].
Topics: Adult; Aged; Biotransformation; Caffeine; Chemical and Drug Induced Liver Injury; Dihydralazine; Female; Follow-Up Studies; Humans; Hydralazine; Liver Function Tests; Male; Middle Aged; Sulfamethazine | 1989 |
Effect of vasodilatators on the structure of the aorta in normotensive ageing rats.
Topics: Aging; Animals; Aorta; Arteries; Blood Pressure; Collagen; Dihydralazine; Elastin; Enalapril; Hydralazine; Male; Rats; Rats, Inbred Strains | 1987 |
Propyldazine is mutagenic in Salmonella typhimurium and Escherichia coli: distinct specificity for strains TA1537 and TA97.
Topics: Animals; Biotransformation; Dihydralazine; Escherichia coli; Hydralazine; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Pyridazines; Rats; Rats, Inbred Strains; Salmonella typhimurium; Species Specificity | 1985 |
[Treatment of hypertension with obsilazin].
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Dihydralazine; Diuretics; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Propranolol; Time Factors | 1986 |
Similar increase in circulating renin after equihypotensive doses of nitroprusside, dihydralazine or isradipine in conscious rabbits.
Topics: Animals; Calcium Channel Blockers; Dihydralazine; Female; Ferricyanides; Hemodynamics; Hydralazine; Isradipine; Male; Nitroprusside; Oxadiazoles; Rabbits; Renin | 1987 |
Effects of antihypertensive treatment in one-clip, two kidney hypertension in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Clonidine; Dihydralazine; Drug Therapy, Combination; Furosemide; Hydralazine; Hypertension, Renovascular; Indoles; Kidney; Male; Organ Size; Perindopril; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Time Factors | 1986 |
Dihydralazine induces marked cerebral vasodilation in man.
Topics: Adult; Blood Pressure; Brain; Cerebrovascular Circulation; Dihydralazine; Heart Rate; Humans; Hydralazine; Pulmonary Gas Exchange; Vasodilation | 1987 |
[Dihydralazine hepatitis].
Topics: Chemical and Drug Induced Liver Injury; Dihydralazine; Humans; Hydralazine; Middle Aged | 1985 |
[The quantitative determination of dihydralazine and selected metabolites in man].
Topics: Biotransformation; Chromatography, Gas; Dihydralazine; Feces; Humans; Hydralazine; Hydrazones | 1988 |
Dihydralazine and the uteroplacental blood flow.
Topics: Dihydralazine; Female; Humans; Hydralazine; Hypertension; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Regional Blood Flow; Uterus | 1988 |
[Chronic drug-induced hepatitis caused by dihydralazine].
Topics: Aged; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Chronic Disease; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Liver; Liver Function Tests; Middle Aged | 1988 |
[The quantitative identification of metabolites of dihydralazine in the human].
Topics: Adult; Aged; Biotransformation; Chromatography, Gas; Chromatography, High Pressure Liquid; Dihydralazine; Female; Humans; Hydralazine; Male; Middle Aged | 1988 |
[Pharmacokinetic interactions between dihydralazine and INH in rabbits].
Topics: Animals; Dihydralazine; Drug Interactions; Hydralazine; Isoniazid; Rabbits | 1988 |
Additive effects of dihydralazine during enflurane or isoflurane hypotensive anaesthesia for spinal fusion.
Topics: Adolescent; Adult; Anesthesia; Anesthetics; Dihydralazine; Drug Synergism; Enflurane; Female; Humans; Hydralazine; Hypotension; Isoflurane; Male; Scoliosis; Spinal Fusion | 1988 |
[Drug-induced hepatitis after dihydralazine treatment with fatal consequences].
Topics: Aged; Chemical and Drug Induced Liver Injury; Dihydralazine; Female; Humans; Hydralazine; Liver; Male; Middle Aged; Necrosis | 1988 |
[Pharmacokinetics of dihydralazine following intravenous administration in laboratory animals].
Topics: Animals; Blood Pressure; Dihydralazine; Dogs; Heart Rate; Hydralazine; Injections, Intravenous; Rabbits; Rats; Species Specificity | 1987 |
[Dihydralazine and intracranial pressure. Risks in the treatment of patients with space-occupying, intracranial processes].
Topics: Aged; Cerebrovascular Circulation; Dihydralazine; Humans; Hydralazine; Hypertension; Intracranial Pressure; Male; Middle Aged; Risk Factors | 1987 |
Cardiovascular actions of dihydralazine as modified by dietary linoleic acid.
Topics: Animals; Aorta, Abdominal; Aspirin; Blood Pressure; Dietary Fats; Dihydralazine; Epoprostenol; Fatty Acids; Female; Hydralazine; In Vitro Techniques; Indomethacin; Kidney; Linoleic Acid; Linoleic Acids; Male; Phospholipids; Pregnancy; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Species Specificity | 1986 |
Dissociation of renin and noradrenaline release in the renal circulation. Studies on patients with renal hypertension.
Topics: Adult; Aged; Diagnosis, Differential; Dihydralazine; Female; Humans; Hydralazine; Hypertension, Renal; Male; Middle Aged; Norepinephrine; Renal Artery; Renal Circulation; Renal Veins; Renin | 1986 |
Interactions of dihydralazine with furosemide in hypertonic patients.
Topics: Adult; Dihydralazine; Drug Interactions; Female; Furosemide; Half-Life; Humans; Hydralazine; Hypertension; Kinetics; Male; Middle Aged; Renal Circulation | 1987 |
The use of dihydralazine infusion in the management of severe hypertension in pregnancy.
Topics: Adult; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Infusions, Intravenous; Pregnancy; Pregnancy Complications, Cardiovascular | 1986 |
[Studies of heart function using apex cardiography in pregnancy-induced hypertension before and following therapy with dihydralazine sulfate].
Topics: Blood Pressure; Dihydralazine; Female; Hemodynamics; Humans; Hydralazine; Kinetocardiography; Myocardial Contraction; Pre-Eclampsia; Pregnancy | 1986 |
Acute effects of dihydralazine mesylate, furosemide, and metoprolol on maternal hemodynamics in pregnancy-induced hypertension.
Topics: Adult; Blood Pressure; Blood Volume; Cardiac Output; Chorionic Villi; Dihydralazine; Female; Furosemide; Heart Rate; Hemodynamics; Humans; Hydralazine; Hypertension; Metoprolol; Pregnancy; Pregnancy Complications, Cardiovascular; Regional Blood Flow | 1986 |
[Blood pressure effects of selected dihydralazine metabolites].
Topics: Animals; Blood Pressure; Dihydralazine; Heart Rate; Hemodynamics; Hydralazine; Muscles; Rats; Regional Blood Flow | 1986 |
[Effect of dihydralazine Spofa on precapillary pulmonary hypertension].
Topics: Adult; Dihydralazine; Female; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Male; Middle Aged | 1986 |
[The effect of dihydralazine on aortic regurgitation].
Topics: Adult; Aortic Valve Insufficiency; Dihydralazine; Female; Hemodynamics; Humans; Hydralazine; Male; Middle Aged | 1986 |
[The binding of propranolol, dihydralazine and selected metabolites to adsorbent resins for hemoperfusion].
Topics: Adsorption; Dihydralazine; Hemoperfusion; Hydralazine; Hydrogen-Ion Concentration; Kinetics; Propranolol; Resins, Plant; Spectrophotometry, Ultraviolet | 1986 |
Effects of dihydralazine infusion on the fetoplacental blood flow and maternal prostanoids.
Topics: 6-Ketoprostaglandin F1 alpha; Blood Pressure; Dihydralazine; Female; Fetal Heart; Humans; Hydralazine; Hypertension; Infusions, Parenteral; Placenta; Pre-Eclampsia; Pregnancy; Pulse; Regional Blood Flow; Thromboxane A2; Umbilical Veins | 1985 |
[Morphology and pathogenesis of liver injury produced by dihydralazine , propranolol and ketophenylbutazone].
Topics: Chemical and Drug Induced Liver Injury; Dihydralazine; Humans; Hydralazine; Immunity, Cellular; Liver Diseases; Phenylbutazone; Propranolol | 1985 |
The influence of the acetylator phenotype for the clinical use of dihydralazine.
Topics: Acetylation; Adult; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Phenotype; Retrospective Studies | 1985 |
Studies on the kinetics and distribution of dihydralazine in pregnancy.
Topics: Administration, Oral; Adolescent; Adult; Amniotic Fluid; Dihydralazine; Female; Fetal Blood; Humans; Hydralazine; Kinetics; Labor, Obstetric; Maternal-Fetal Exchange; Milk, Human; Pregnancy; Pregnancy Trimester, Third | 1986 |
[Liver lesions induced by dihydralazine and propranolol].
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Cholangitis; Dihydralazine; Female; Humans; Hydralazine; Liver; Male; Middle Aged; Necrosis; Propranolol | 1985 |
[Drug-induced hepatitis in a diabetic patient].
Topics: Adult; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Type 1; Dihydralazine; Humans; Hydralazine | 1985 |
[Role of dihydralazine in the treatment of chronic cardiac insufficiency].
Topics: Aged; Arterioles; Cardiac Output; Chronic Disease; Dihydralazine; Follow-Up Studies; Heart Failure; Hemodynamics; Humans; Hydralazine; Middle Aged; Vascular Resistance; Vasodilator Agents | 1985 |
[Dihydralazine treatment of cardiac insufficiency in children].
Topics: Dihydralazine; Heart Failure; Humans; Hydralazine; Infant | 1985 |
[Dihydralazine treatment of cardiac insufficiency in children].
Topics: Adolescent; Child; Child, Preschool; Dihydralazine; Drug Evaluation; Female; Heart Failure; Humans; Hydralazine; Infant; Male; Vasodilator Agents | 1985 |
Liquid chromatographic determination of dihydralazine and hydralazine in human plasma and its application to pharmacokinetic studies of dihydralazine.
Topics: Adult; Chromatography, Liquid; Dihydralazine; Drug Stability; Half-Life; Humans; Hydralazine; Kinetics; Male | 1985 |
[The so-called dihydralazine hepatitis. A contribution to the pathogenesis].
Topics: Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hydralazine; Liver; Liver Cirrhosis, Biliary; Male; Middle Aged; Necrosis; Propranolol | 1985 |
[Quantitative determination and kinetics of dihydralazine in hypertension patients].
Topics: Acetylation; Adult; Aged; Bile; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Kinetics; Male; Middle Aged; Phenotype | 1985 |
[Comparison of the cardiac, renal and endocrine effects of converting enzyme inhibition with those of a classical triple therapy in experimental renal hypertension].
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Volume; Clonidine; Dihydralazine; Drug Therapy, Combination; Furosemide; Heart Ventricles; Hydralazine; Hypertension, Renovascular; Kidney; Male; Organ Size; Perindopril; Rats; Rats, Inbred Strains; Renin-Angiotensin System | 1984 |
Dihydralazine inhibits tyrosine hydroxylase in vivo in the rat.
Topics: Animals; Brain; Cerebral Cortex; Corpus Striatum; Dihydralazine; Dopamine; Heart; Hydralazine; Male; Norepinephrine; Rats; Rats, Inbred Strains; Tyrosine 3-Monooxygenase | 1982 |
[Forum on hypertension. Part 8. Hypertension management in pregnancy].
Topics: Antihypertensive Agents; Dihydralazine; Diuretics; Female; Humans; Hydralazine; Hypertension; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular; Receptors, Adrenergic, beta | 1981 |
[Antihypertensive vasodilators].
Topics: Antihypertensive Agents; Chemical Phenomena; Chemistry; Diazoxide; Dihydralazine; Humans; Hydralazine; Minoxidil; Nitroprusside; Prazosin; Vasodilator Agents | 1983 |
Compared myocardial and vascular effects of captopril and dihydralazine during hypertension development in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Blood Vessels; Captopril; Dihydralazine; Heart; Hydralazine; Hypertension; Male; Organ Size; Proline; Rats; Rats, Inbred Strains | 1983 |
Blood pressure response and renin release following 4 days of treatment with dihydralazine and urapidil in conscious dogs.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dihydralazine; Dogs; Dose-Response Relationship, Drug; Drug Tolerance; Female; Heart Rate; Hydralazine; Male; Piperazines; Renin; Time Factors | 1984 |
[Use of vasodilators in pediatric cardiology: left-right shunt modification by dihydralazine (Depressan)].
Topics: Child; Child, Preschool; Dihydralazine; Heart Septal Defects, Ventricular; Hemodynamics; Humans; Hydralazine; Infant | 1984 |
Influence of dihydralazine induced afterload reduction on systolic time intervals and echocardiography in healthy subjects.
Topics: Autonomic Nerve Block; Dihydralazine; Echocardiography; Female; Heart Rate; Hemodynamics; Humans; Hydralazine; Male; Myocardial Contraction; Random Allocation; Stroke Volume; Systole; Time Factors | 1984 |
Liminal therapy: a strategy for the complete and selective destruction of malignant tissue in situ.
Topics: Animals; Antineoplastic Agents; Cell Survival; Dihydralazine; Drug Resistance; Energy Metabolism; Humans; Hydralazine; Isoproterenol; Mice; Naphazoline; Neoplasms; Oxygen; Oxygen Consumption; Phenylephrine; Sarcoma, Experimental; Time Factors; Vasopressins | 1984 |
Cerebrovascular effects of dihydralazine in hypertensive and normotensive rats.
Topics: Animals; Arteries; Blood Pressure; Cerebrovascular Circulation; Dihydralazine; Female; Homeostasis; Hydralazine; Hypertension; Male; Phenoxybenzamine; Pia Mater; Rats; Rats, Inbred Strains; Vasodilation; Veins | 1983 |
Effect of dihydralazine on intracranial pressure in patients with severe brain damage.
Topics: Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Dihydralazine; Homeostasis; Humans; Hydralazine; Intracranial Pressure; Time Factors; Vasodilation | 1983 |
Acute effect of dihydralazine on uteroplacental blood flow in hypertension during pregnancy.
Topics: Blood Pressure; Dihydralazine; Female; Heart Rate; Humans; Hydralazine; Hypertension; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Regional Blood Flow; Uterus | 1983 |
Hemodynamic effects of the arteriolar vasodilators hydralazine, dihydralazine and endralazine in the conscious spontaneously hypertensive rat.
Topics: Animals; Denervation; Dihydralazine; Hemodynamics; Hydralazine; Hypertension; Male; Pressoreceptors; Pyridazines; Rats; Vasodilator Agents | 1983 |
[Long-term treatment of arterial hypertension with a new combined preparation obsilazin].
Topics: Blood Pressure; Dihydralazine; Drug Combinations; Humans; Hydralazine; Hypertension; Propranolol; Propylamines; Time Factors | 1983 |
[Hypotensive anaesthesia in the oto-rhino-laryngological surgery using nitroglycerine (author's transl)].
Topics: Acid-Base Equilibrium; Adolescent; Adult; Aged; Blood Pressure; Child; Child, Preschool; Dihydralazine; Drug Synergism; Heart Rate; Humans; Hydralazine; Hypotension, Controlled; Middle Aged; Nitroglycerin; Nitroprusside; Otorhinolaryngologic Diseases | 1980 |
[Study of the effects on coronary circulation and myocardial metabolism of a single intravenous dose of dihydralazine in 10 cases of primary myocardiopathy].
Topics: Adult; Blood Pressure; Cardiomyopathies; Coronary Circulation; Dihydralazine; Female; Heart Rate; Humans; Hydralazine; Injections, Intravenous; Lactates; Male; Middle Aged; Myocardium; Oxygen Consumption | 1980 |
[Acute and chronic effects of dihydralazine in severe congestive heart failure at rest and during exercise (author's transl)].
Topics: Adult; Aged; Dihydralazine; Female; Heart Failure; Hemodynamics; Humans; Hydralazine; Long-Term Care; Male; Middle Aged; Physical Exertion | 1982 |
[Comparative hemodynamic effects of 2 vasodilators: dihydralazine and diltiazem in permanent essential arterial hypertension].
Topics: Adult; Arteries; Arterioles; Benzazepines; Blood Pressure; Dihydralazine; Diltiazem; Heart Rate; Hemodynamics; Humans; Hydralazine; Hypertension; Middle Aged; Vascular Resistance; Vasodilator Agents | 1982 |
Baroreflex response and vasodilating drugs in essential hypertension.
Topics: Adult; Benzazepines; Blood Pressure; Brachial Artery; Dihydralazine; Diltiazem; Heart Rate; Humans; Hydralazine; Hypertension; Isosorbide Dinitrate; Male; Middle Aged; Pressoreceptors; Reflex; Vascular Resistance | 1983 |
[Dihydralazine-induced hepatitis with bridging necrosis. A clinico-pathologic survey of 20 cases].
Topics: Adolescent; Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Dihydralazine; Female; Humans; Hydralazine; Liver; Male; Middle Aged; Necrosis; Recurrence; Time Factors | 1983 |
Dihydralazine hepatitis: report of a case and review of the literature.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Dihydralazine; Hepatic Encephalopathy; Humans; Hydralazine; Hypertension; Liver; Male; Middle Aged; Prothrombin Time | 1983 |
Effect of dihydralazine on the renal kallikrein-kinin system of the rat.
Topics: Animals; Blood Pressure; Dihydralazine; Hydralazine; Kallikreins; Kidney; Kidney Cortex; Kinins; Male; Rats; Rats, Inbred Strains; Water-Electrolyte Balance | 1982 |
Augmented acute hypotensive effect of dihydralazine and clonidine after linoleic acid rich diet in normotensive conscious rats.
Topics: Animals; Blood Pressure; Clonidine; Dietary Fats; Dihydralazine; Drug Interactions; Heart Rate; Hydralazine; Linoleic Acid; Linoleic Acids; Male; Rats; Rats, Inbred Strains; Time Factors | 1982 |
The effect of low-dose dihydrallazine on the fetus in the emergency treatment of hypertension in pregnancy.
Topics: Blood Pressure; Depression, Chemical; Dihydralazine; Female; Fetal Growth Retardation; Fetal Heart; Heart Rate; Humans; Hydralazine; Hypertension; Infant Mortality; Pregnancy; Pregnancy Complications, Cardiovascular; Prospective Studies; Time Factors; Uterine Contraction | 1982 |
In vivo and in vitro genotoxicity of three antihypertensive hydrazine derivatives (hydralazine, dihydralazine, and endralazine).
Topics: Animals; Antihypertensive Agents; Dihydralazine; DNA Repair; Genes; Hydralazine; In Vitro Techniques; Male; Mice; Mutagenicity Tests; Mutagens; Pyridazines; Sister Chromatid Exchange | 1982 |
[More on the comparison of minoxidil with dihydralazine].
Topics: Dihydralazine; Humans; Hydralazine; Hypertension; Minoxidil; Pyrimidines | 1982 |
Determination of apparent dihydralazine in plasma by gas--liquid chromatography and electron-capture detection.
Topics: Chromatography, Gas; Dihydralazine; Humans; Hydralazine; Male; Time Factors | 1982 |
Vascular effects of dihydralazine during prevention of genetic hypertension development in SHR rats.
Topics: Animals; Aorta; Dihydralazine; Hydralazine; Hypertension; Male; Mesenteric Arteries; Rats; Rats, Inbred Strains; Vascular Resistance | 1982 |
[Morphologic observations in liver damage in patients taking Depressan (dihydralazinum sulfuricum)].
Topics: Antihypertensive Agents; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Dihydralazine; Humans; Hydralazine; Liver; Male; Middle Aged; Necrosis | 1981 |
[Acute liver damage in patients treated with a depressant (dihydralazine sulfate)].
Topics: Acute Disease; Aged; Chemical and Drug Induced Liver Injury; Dihydralazine; Female; Humans; Hydralazine; Liver; Male; Middle Aged; Necrosis | 1981 |
The influence of dihydralazine and angiotensin-II blockade on renal extraction of [131I]hippuran.
Topics: Adult; Angiotensin II; Dihydralazine; Female; Humans; Hydralazine; Iodohippuric Acid; Kidney; Male; Middle Aged; Radiography; Renal Circulation | 1981 |
Effect of dihydralazine on the fetus in the treatment of maternal hypertension.
Topics: Birth Weight; Dihydralazine; Female; Fetal Death; Fetal Growth Retardation; Fetal Heart; Fetal Monitoring; Fetus; Heart Rate; Humans; Hydralazine; Hypertension; Infant Mortality; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Uterine Contraction | 1980 |
[Alteration in left ventricular function induced by dihydralazine in severe chronic congestive heart failure: limits of vasodilator therapy? (author's transl)].
Topics: Chronic Disease; Dihydralazine; Heart Diseases; Heart Ventricles; Hemodynamics; Humans; Hydralazine | 1980 |
[Rare liver damage caused by an antihypertensive and anti-arrhythmic agents].
Topics: Adult; Ajmaline; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Dihydralazine; Female; Humans; Hydralazine; Liver; Necrosis | 1980 |
Genotoxicity of the antihypertensive drugs hydralazine and dihydralazine.
Topics: Acetylation; Animals; Biotransformation; Carcinogens; Cells, Cultured; Dihydralazine; DNA Repair; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hydralazine; Liver; Mutagens; Rats; Salmonella typhi | 1980 |
[Treatment of hypertension with clofelin and adelfan-esidrex].
Topics: Adolescent; Adult; Antihypertensive Agents; Clonidine; Dihydralazine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Reserpine | 1980 |
Mutagenicity of B(a)P in the presence of some hydralazine derivatives.
Topics: Antimutagenic Agents; Benzo(a)pyrene; Dihydralazine; Dose-Response Relationship, Drug; Drug Interactions; Hydralazine; Mutagenicity Tests; Todralazine | 1993 |
Interaction of myeloperoxidase and elastase enzyme activity with the antihypertensive agents hydralazine and dihydralazine.
Topics: Ampyrone; Animals; Benzothiazoles; Cattle; Dihydralazine; Drug Interactions; Humans; Hydralazine; Indicators and Reagents; Kinetics; Pancreatic Elastase; Peroxidase; Sulfonic Acids | 1993 |
Studies on the mutagenic activity of hydralazine and dihydralazine in Salmonella typhimurium strains differing in expression of antioxidant genes.
Topics: Antihypertensive Agents; Dihydralazine; DNA Damage; DNA-Binding Proteins; Hydralazine; Mutagens; Oxidative Stress; Repressor Proteins; Salmonella typhimurium; Superoxides; Transcription Factors | 1999 |
Influence of metabolic activation on the induction of micronuclei by antihypertensive drugs in L929 cells.
Topics: Animals; Antihypertensive Agents; Aroclors; Biotransformation; Catalase; Cell Line; Connective Tissue; Dihydralazine; Enzyme Activation; Hot Temperature; Hydralazine; Male; Mice; Micronucleus Tests; Microsomes, Liver; Mutagens; Rats; Rats, Wistar; Superoxide Dismutase | 2001 |
Pharmacological properties of hydrallazine, dihydrallazine and some related compounds.
Topics: Dihydralazine; Humans; Hydralazine | 1957 |
Adelphane in essential hypertension.
Topics: Dihydralazine; Drug Combinations; Essential Hypertension; Humans; Hydralazine; Hypertension; Reserpine | 1958 |
Site of action of hydralazine and dihydralazine in man.
Topics: Dihydralazine; Humans; Hydralazine; Male | 1959 |
THE PROBLEM OF THE ARTERIO-VENOUS ANASTOMOSES IN THE KIDNEY. II. EFFECT OF HUMAN SERUM ALBUMIN AND DIHYDRALAZINE ON THE OPENING OF RENAL SHUNTS.
Topics: Albumins; Animals; Arteriovenous Anastomosis; Arteriovenous Shunt, Surgical; Blood Circulation; Dihydralazine; Dogs; Humans; Hydralazine; Kidney; Oximetry; Pharmacology; Renal Artery; Renal Veins; Research; Serum Albumin | 1964 |
Application of arylosulfonic acids in analysis of antidepressive drugs.
Topics: Antidepressive Agents; Arylsulfonates; Dihydralazine; Hydralazine; Indicators and Reagents; Todralazine | 1992 |