hydralazine has been researched along with decitabine in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Acuña, C; Chavez, A; Dueñas-Gonzalez, A; Lizano, M; Mariscal, I; Perez-Cardenas, E; Salazar, AM; Segura-Pacheco, B; Taja-Chayeb, L; Trejo-Becerril, C | 1 |
| Gorbunova, V; Mittelman, D; Seluanov, A; Wilson, JH | 1 |
| Chuang, JC; Jones, PA; Kwan, JM; Li, TW; Liang, G; Yang, AS; Yoo, CB | 1 |
| Ip, CK; Lai, KP; Law, AY; Wagner, GF; Wong, AS; Wong, CK | 1 |
| Arias-Bofill, D; Candelaria, M; Cervera, E; de la Cruz-Hernández, E; Dueñas-Gonzalez, A; González-Fierro, A; Herrera, A; Labardini, J; Pérez-Cárdenas, E; Taja-Chayeb, L; Trejo-Becerril, C; Vidal, S | 1 |
| Chie, EK; Kim, HJ; Kim, IA; Kim, IH; Kim, JH; Young, PD | 1 |
| Chiaratti, MR; de Araújo, RR; De Bem, TH; Meirelles, FV; Oliveira, Lde J; Perecin, F; Sangalli, JR; Smith, LC; Valim Pimentel, JR | 1 |
| Butter, R; Linnekamp, JF; Medema, JP; Spijker, R; van Laarhoven, HWM | 1 |
2 review(s) available for hydralazine and decitabine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Clinical and biological effects of demethylating agents on solid tumours - A systematic review.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cytidine; Decitabine; DNA Methylation; Humans; Hydralazine; Immune System; Methylation; Neoplasms; Procaine; Treatment Outcome | 2017 |
2 trial(s) available for hydralazine and decitabine
| Article | Year |
|---|---|
Hydralazine and magnesium valproate as epigenetic treatment for myelodysplastic syndrome. Preliminary results of a phase-II trial.
Topics: Adult; Aged; Azacitidine; Cytogenetic Analysis; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Modification Methylases; Epigenomics; Female; Histone Deacetylase Inhibitors; Humans; Hydralazine; Kaplan-Meier Estimate; Male; Middle Aged; Myelodysplastic Syndromes; Treatment Outcome; Valproic Acid; Young Adult | 2011 |
Treatment of nuclear-donor cells or cloned zygotes with chromatin-modifying agents increases histone acetylation but does not improve full-term development of cloned cattle.
Topics: Acetylation; Animals; Azacitidine; Cattle; Cell Nucleus; Cells, Cultured; Chromatin Assembly and Disassembly; Cloning, Organism; Decitabine; Embryonic Development; Female; Histone Deacetylase Inhibitors; Histones; Hydralazine; Hydroxamic Acids; Nuclear Transfer Techniques; Pregnancy; Term Birth; Up-Regulation; Valproic Acid; Zygote | 2012 |
8 other study(ies) available for hydralazine and decitabine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Head and Neck Neoplasms; Humans; Hydralazine; Mice; Mice, Nude; Procainamide; Receptors, Estrogen; Receptors, Retinoic Acid; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2003 |
Genome-wide demethylation destabilizes CTG.CAG trinucleotide repeats in mammalian cells.
Topics: Animals; Azacitidine; CHO Cells; CpG Islands; Cricetinae; Decitabine; DNA Methylation; Genome, Human; Humans; Hydralazine | 2004 |
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Transitional Cell; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Cytidine; Decitabine; Deoxycytidine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Silencing; HT29 Cells; Humans; Hydralazine; Male; Procainamide; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction | 2005 |
Epigenetic and HIF-1 regulation of stanniocalcin-2 expression in human cancer cells.
Topics: Azacitidine; Base Sequence; Cell Hypoxia; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Glycoproteins; Humans; Hydralazine; Hypoxia-Inducible Factor 1, alpha Subunit; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Promoter Regions, Genetic; RNA Interference; Transcriptional Activation | 2008 |
DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity.
Topics: Azacitidine; Caspase 3; Catechin; Cell Line, Tumor; Cytidine; Decitabine; Disulfides; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Breaks, Double-Stranded; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Repair; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Hydralazine; Inhibitory Concentration 50; Lung Neoplasms; Neoplasm Proteins; Radiation-Sensitizing Agents; Tumor Stem Cell Assay; Tyrosine | 2012 |