Compounds > hydralazine

hydralazine and dapsone

hydralazine has been researched along with dapsone in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (33.33)	18.7374
1990's	1 (8.33)	18.2507
2000's	3 (25.00)	29.6817
2010's	4 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Benedetto, EA; Bergfeld, WF; Fleming, MG; Norris, M; Tomecki, KJ; Tuthill, RJ; Weber, LA	1
Gordon, GR; Peters, JH; Shafizadeh, AG	1
Skakun, NP	1
Ahmad, RA; Rogers, HJ; Vandenburg, M; Wright, P	1
Park, BK; Tingle, MD	1

Reviews

3 review(s) available for hydralazine and dapsone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Bullous systemic lupus erythematosus. International journal of dermatology, 1989, Volume: 28, Issue:5 Topics: Adult; Aged; Dapsone; Female; Fluorescent Antibody Technique; Humans; Hydralazine; Lupus Erythematosus, Systemic; Skin Diseases, Vesiculobullous	1989
[Pharmacokinetics of drug preparations metabolized by N-acetyltransferase]. Klinicheskaia meditsina, 1982, Volume: 60, Issue:1 Topics: Acetylation; Acetyltransferases; Dapsone; Humans; Hydralazine; Inactivation, Metabolic; Isoniazid; Kinetics; Liver; Pharmaceutical Preparations; Phenotype; Procainamide; Sulfamethazine; Sulfasalazine	1982

Other Studies

9 other study(ies) available for hydralazine and dapsone

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Polymorphic acetylation of drugs in rabbits. Xenobiotica; the fate of foreign compounds in biological systems, 1973, Volume: 3, Issue:3 Topics: Acetylation; Aminobenzoates; Aminosalicylic Acids; Animals; Body Temperature; Chromatography, Thin Layer; Dapsone; Female; Genotype; Half-Life; Hydralazine; Intestine, Small; Isoniazid; Lethal Dose 50; Liver; Male; Methemoglobinemia; Phenotype; Polymorphism, Genetic; Rabbits; Structure-Activity Relationship; Sulfamethazine; Sulfanilamides; Time Factors	1973
Effects of concurrent administration of other substrates of N-acetyltransferase on dapsone acetylation. British journal of clinical pharmacology, 1981, Volume: 12, Issue:1 Topics: Acetylation; Acetyltransferases; Animals; Dapsone; Humans; Hydralazine; In Vitro Techniques; Isoniazid; Rats; Sulfamethazine	1981
The use of a three compartment in vitro model to investigate the role of hepatic drug metabolism in drug-induced blood dyscrasias. British journal of clinical pharmacology, 1993, Volume: 36, Issue:1 Topics: Animals; Dapsone; Drug-Related Side Effects and Adverse Reactions; Erythrocyte Count; Hematologic Diseases; Humans; Hydralazine; In Vitro Techniques; Liver; Male; Methemoglobin; Microsomes, Liver; Models, Biological; Neutrophils; Pharmaceutical Preparations; Primaquine; Procainamide; Rats; Rats, Wistar	1993