hydralazine and chlorthalidone

hydralazine has been researched along with chlorthalidone in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	33 (80.49)	18.7374
1990's	1 (2.44)	18.2507
2000's	5 (12.20)	29.6817
2010's	2 (4.88)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Fusco, M; Lombardo, M; Valente, D	1
Angelino, PF; Castaldo, D; Lavezzaro, GC	1
Manegold, C; Patzschke, U	1
Sullivan, JM	1
Belasco, RN; Moyer, JP; Pittman, AW; Woods, JW	1
Dirix, R; Savoye, D; Tyberghein, JM	1
Franz, IW; Lohmann, FW	1
Hart, M; Stone, KJ	1
Koene, R; Wijdeveld, P	1
Pillay, VK	1
Caldwell, JR	1
Cohen, JD	1
Black, DM; Furberg, CD	1
Branche, G; Chiles, B; Garnier, C; Kilcoyne, MM; Soland, T; Thomson, GE; Williams, M	1
Moyer, JH; Onesti, G	1
Feltkamp, TE; ten Veen, JH	1
ten Veen, JH	1
Comerford, MB; Pringle, A	1
Johnsson, G	1
Carstens, E	1
Finnerty, FA	1
Haller, J	1
Kishimoto, M	2
Zanchetti, A	1
Davidov, M; Finnerty, FA; Kakaviatos, N	1
Krönig, B; Wendt, G	1
Hilgert, A; Horch, G	1
Perry, HM	1
Algueti, A; Aviram, A; Ayalon, D; Bauminger, S; Blum, M	1
MATHISEN, HS	1
FREIS, ED	1
BOETTIGER, LE; MALMBORG, RO; MICHAELI, EW	1
MIZGALA, HF	1
Christian, R; Colon, PJ; Cushman, WC; Einhorn, PT; Ford, CE; Goff, DC; Henriquez, MA; Margolis, KL; Piller, LB; Vidt, DG; Wong, ND; Wright, JT	1
Black, HR; Slim, HB; Thompson, PD	1

Reviews

5 review(s) available for hydralazine and chlorthalidone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Physiologic and biochemical profile of hypertension for rational clinical management. Advances in internal medicine, 1978, Volume: 23 Topics: Adrenal Gland Diseases; Angiotensins; Body Fluid Compartments; Chlorthalidone; Diuretics; Guanethidine; Hemodynamics; Humans; Hydralazine; Hypertension; Hypertension, Renal; Nephritis; Plasma Volume; Propranolol; Renin; Sympathetic Nervous System	1978
[Side effects of antihypertensive agents]. Saishin igaku. Modern medicine, 1971, Volume: 26, Issue:12 Topics: Antihypertensive Agents; Autonomic Agents; Benzothiadiazines; Benzyl Compounds; Carbamates; Chlorthalidone; Clonidine; Guanethidine; Guanidines; Humans; Hydralazine; Methyldopa; Plants, Medicinal; Plants, Toxic; Rauwolfia; Veratrum	1971
NEWER DRUGS IN THE TREATMENT OF HYPERTENSION. Canadian Medical Association journal, 1965, Apr-24, Volume: 92 Topics: Antihypertensive Agents; Bretylium Compounds; Chlorothiazide; Chlorthalidone; Diuretics; Drug Therapy; Essential Hypertension; Guanethidine; Hydralazine; Hypertension; Methyldopa; Pargyline; Rauwolfia; Spironolactone; Toxicology	1965
Older blood pressure medications-do they still have a place? The American journal of cardiology, 2011, Jul-15, Volume: 108, Issue:2 Topics: Antihypertensive Agents; Chlorthalidone; Clonidine; Diuretics; Ethacrynic Acid; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Reserpine; Spironolactone; Vasodilator Agents	2011

Trials

7 trial(s) available for hydralazine and chlorthalidone

Article	Year
The systolic hypertension in the elderly pilot program: methodological issues. European heart journal, 1988, Volume: 9, Issue:2 Topics: Age Factors; Aged; Aged, 80 and over; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Double-Blind Method; Feasibility Studies; Female; Humans; Hydralazine; Hypertension; Male; Metoprolol; Middle Aged; Patient Compliance; Pilot Projects; Random Allocation; Reserpine; Sex Factors; Systole	1988
A long-term study of the antihypertensive effect of alprenolol. Acta medica Scandinavica. Supplementum, 1974, Volume: 554 Topics: Adult; Aged; Alprenolol; Blood Pressure Determination; Chlorthalidone; Clinical Trials as Topic; Delayed-Action Preparations; Drug Evaluation; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Humans; Hydralazine; Hypertension; Male; Middle Aged; Placebos; Posture; Propranolol; Time Factors	1974
Alprenolol in hypertension. Acta medica Scandinavica. Supplementum, 1974, Volume: 554 Topics: Aged; Alprenolol; Benzothiadiazines; Chlorthalidone; Clinical Trials as Topic; Digitalis; Diuretics; Drug Evaluation; Drug Therapy, Combination; Female; Heart Failure; Humans; Hydralazine; Hypertension; Methyldopa; Phytotherapy; Placebos; Plants, Medicinal; Plants, Toxic; Sodium Chloride Symporter Inhibitors; Time Factors	1974
[Treatment of refractory hypertension with a fixed oxprenolol/chlorthalidone/hydralazine combination. Results of an open multicenter trial]. Die Medizinische Welt, 1983, Sep-02, Volume: 34, Issue:35 Topics: Chlorthalidone; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydralazine; Hypertension; Isoindoles; Male; Middle Aged; Oxprenolol	1983
[Long-term experiences with an antihypertensive combination]. Die Medizinische Welt, 1982, Jul-30, Volume: 33, Issue:29-30 Topics: Chlorthalidone; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydralazine; Hypertension; Male; Oxprenolol	1982
Effect of antihypertensive drugs on plasma renin activity and urinary excretion of prostaglandin E2. Prostaglandins and medicine, 1981, Volume: 7, Issue:4 Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Dinoprostone; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Propranolol; Prostaglandins E; Renin	1981
Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:5 Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Canada; Chlorthalidone; Clonidine; Double-Blind Method; Doxazosin; Female; Heart Diseases; Hispanic or Latino; Humans; Hydralazine; Hypertension; Hypolipidemic Agents; Lisinopril; Male; Middle Aged; Puerto Rico; Reserpine; Treatment Outcome; United States; United States Virgin Islands; White People	2007

Other Studies

29 other study(ies) available for hydralazine and chlorthalidone

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
[The role of renin after betablocking diuretic and vasodilator treatment in essential hypertension (author's transl)]. Giornale italiano di cardiologia, 1979, Volume: 9, Issue:12 Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Chlorthalidone; Diuretics; Drug Therapy, Combination; Female; Heart Septal Defects, Ventricular; Humans; Hydralazine; Male; Middle Aged; Oxprenolol; Renin; Vasodilator Agents	1979
[Combination of beta-blocking agents, diuretics and pressidil (minoxidil) in severe arterial hypertension resisting other therapy]. Bollettino della Societa italiana di cardiologia, 1978, Volume: 23, Issue:9 Topics: Adrenergic beta-Antagonists; Adult; Chlorthalidone; Diuretics; Drug Therapy, Combination; Female; Furosemide; Guanethidine; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; Minoxidil; Propranolol; Pyrimidines	1978
[Regression of left ventricular hypertophy in the ECG during antihypertensive treatment: preliminary observations (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1979, Jun-08, Volume: 104, Issue:23 Topics: Adult; Aged; Cardiomegaly; Chlorthalidone; Electrocardiography; Female; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; Reserpine	1979
Echocardiographic assessment of the effect of an antihypertensive regimen on left ventricular performance. The American journal of cardiology, 1979, Volume: 43, Issue:3 Topics: Adult; Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Chlorthalidone; Coronary Disease; Echocardiography; Female; Hemodynamics; Humans; Hydralazine; Hypertension; Male; Middle Aged; Myocardial Contraction; Propranolol; Stimulation, Chemical	1979
Drug treatment of essential hypertension. Practical guidelines. The Practitioner, 1979, Volume: 222, Issue:1331 Topics: Adult; Aged; Chlorthalidone; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines	1979
[Ergometry in the assessment of antihypertensive treatment (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1978, Sep-22, Volume: 103, Issue:38 Topics: Adult; Aged; Antihypertensive Agents; Chlorthalidone; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Oxprenolol; Physical Exertion	1978
Inhibition of renal PGE2-9-ketoreductase by diuretics. Prostaglandins, 1976, Volume: 12, Issue:2 Topics: Alcohol Oxidoreductases; Animals; Chlorthalidone; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hydralazine; Hydroxyprostaglandin Dehydrogenases; Indomethacin; Kidney Cortex; Phentolamine; Prostaglandins E; Rabbits; Rats; Thiazines	1976
[Diazoxide: new way in treatment of hypertension]. Nederlands tijdschrift voor geneeskunde, 1975, Mar-15, Volume: 119, Issue:11 Topics: Adult; Chlorthalidone; Diazoxide; Diet, Sodium-Restricted; Female; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; Propranolol; Tolbutamide; Water-Electrolyte Balance	1975
Some side-effects of alpha-methyldopa. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1976, Apr-10, Volume: 50, Issue:16 Topics: Adult; Aged; Chlorthalidone; Drug Therapy, Combination; Erectile Dysfunction; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; Propranolol	1976
Drug regimens for long-term therapy of hypertension. Geriatrics, 1976, Volume: 31, Issue:1 Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Patient Compliance; Propranolol; Time Factors	1976
Abnormal electrocardiograms and cardiovascular risk: role of silent myocardial ischemia. Evidence from MRFIT. The American journal of cardiology, 1992, Nov-16, Volume: 70, Issue:16 Topics: Adult; Antihypertensive Agents; Chlorthalidone; Cholesterol, Dietary; Coronary Disease; Electrocardiography; Humans; Hydralazine; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; Male; Middle Aged; Missouri; Myocardial Ischemia; Reserpine; Risk Factors; Smoking; Smoking Cessation; Smoking Prevention	1992
Characteristics of hypertension in the black population. Circulation, 1974, Volume: 50, Issue:5 Topics: Adult; Angiotensin II; Animals; Black or African American; Cardiomegaly; Cerebrovascular Disorders; Chlorthalidone; Coronary Disease; Drug Therapy, Combination; Female; Guanethidine; Heart Ventricles; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; New York City; Rabbits; Radioimmunoassay; Renin; Sodium; Spironolactone	1974
Hypertension past 60. Geriatrics, 1967, Volume: 22, Issue:3 Topics: Aged; Benzothiadiazines; Chlorthalidone; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Middle Aged; Pargyline; Phytotherapy; Plants, Medicinal; Rauwolfia; Reserpine	1967
Studies on drug induced lupus erythematosus in mice. I. Drug induced antinuclear antibodies (ANA). Clinical and experimental immunology, 1972, Volume: 11, Issue:2 Topics: Administration, Oral; Animals; Antibodies, Antinuclear; Antibody Formation; Chlorthalidone; Coombs Test; DNA; Female; Fluorescent Antibody Technique; Genetics; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male; Methyldopa; Mice; Mice, Inbred Strains; Procainamide; Sex Factors	1972
Studies on drug-induced lupus erythematosus in mice. II. Drug-induced smooth muscle and skeletal muscle antibodies. Clinical and experimental immunology, 1973, Volume: 15, Issue:3 Topics: Animals; Antibody Formation; Autoantibodies; Cell Membrane; Chlorthalidone; Fluorescent Antibody Technique; Hydralazine; Isoniazid; Liver; Lupus Erythematosus, Systemic; Lymphocytes; Methyldopa; Mice; Mice, Inbred A; Mice, Inbred BALB C; Mice, Inbred C57BL; Muscle, Smooth; Muscles; Procainamide	1973
[Antihypertensive agents]. Die Pharmazie, 1972, Volume: 27, Issue:11 Topics: Acetazolamide; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Chlorisondamine; Chlorthalidone; Diuretics; Furosemide; Guanethidine; Guanidines; Hexamethonium Compounds; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypotension; Mecamylamine; Methyldopa; Pain; Parotid Gland; Pempidine; Phentolamine; Structure-Activity Relationship; Sulfonamides	1972
How to treat arterial hypertension. American family physician, 1973, Volume: 7, Issue:4 Topics: Antihypertensive Agents; Chlorothiazide; Chlorthalidone; Cooperative Behavior; Diazoxide; Diuretics; Ethacrynic Acid; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Methyldopa; Physician-Patient Relations; Reserpine; Spironolactone; Sulfonamides; Triamterene	1973
[Therapy of EPH gestosis]. Deutsche medizinische Wochenschrift (1946), 1973, Jul-06, Volume: 98, Issue:27 Topics: Chlorthalidone; Diazepam; Diet Therapy; Eclampsia; Edema; Female; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Magnesium Sulfate; Mannitol; Phenobarbital; Phytotherapy; Plants, Medicinal; Pre-Eclampsia; Pregnancy; Proteinuria; Rauwolfia	1973
[Hypertension]. Naika. Internal medicine, 1971, Volume: 27, Issue:6 Topics: Aged; Allopurinol; Antihypertensive Agents; Benzothiadiazines; Chlordiazepoxide; Chlorthalidone; Diazepam; Diet Therapy; Female; Guanethidine; Guanidines; Humans; Hydralazine; Hypertension; Imidazoles; Male; Methyldopa; Middle Aged; Phytotherapy; Plants, Medicinal; Rauwolfia; Trimethaphan	1971
[Objectives and methods in therapy of essential arterial hypertension]. Cardiologia pratica, 1968, Volume: 19, Issue:4 Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Ethacrynic Acid; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Potassium; Reserpine; Triamterene	1968
Hypertensive vascular disease. The long term effect of rapid repeated reductions of arterial pressure with diazoxide. The American journal of cardiology, 1967, Volume: 19, Issue:3 Topics: Adult; Chlorthalidone; Diazoxide; Female; Heart Failure; Humans; Hydralazine; Hypertension; Injections, Intravenous; Male; Methyldopa; Middle Aged; Reserpine	1967
Some wrong-way chemical changes during antihypertensive treatment: comparison of indapamide and related agents. American heart journal, 1983, Volume: 106, Issue:1 Pt 2 Topics: Adult; Antihypertensive Agents; Chemical Phenomena; Chemistry; Chlorthalidone; Diuretics; Humans; Hydralazine; Hydrochlorothiazide; Hypercholesterolemia; Hyperglycemia; Hypokalemia; Indapamide; Middle Aged; Myocardial Infarction; Uric Acid	1983
[DRUG THERAPY OF HIGH BLOOD PRESSURE IN THE PAST, PRESENT AND FUTURE]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1963, Nov-15, Volume: 83 Topics: Antihypertensive Agents; Chlorothiazide; Chlorthalidone; Guanethidine; Humans; Hydralazine; Hypertension; Mecamylamine; Monoamine Oxidase Inhibitors; Pentolinium Tartrate; Pharmacology; Rauwolfia; Spironolactone; Veratrum	1963
HYDRALAZINE IN HYPERTENSION. American heart journal, 1964, Volume: 67 Topics: Chlorthalidone; Humans; Hydralazine; Hypertension; Reserpine	1964
[SEVERE NEUROLOGICAL SIDE-EFFECTS IN HYPOTENSION THERAPY]. Nordisk medicin, 1964, Apr-23, Volume: 71 Topics: Amobarbital; Antihypertensive Agents; Arteriosclerosis; Chlorothiazide; Chlorthalidone; Guanethidine; Hemiplegia; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypotension; Methyldopa; Neurologic Manifestations; Reserpine; Toxicology	1964