hydralazine has been researched along with caffeine in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (18.18) | 18.7374 |
| 1990's | 7 (31.82) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 5 (22.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Branch, KR; Jackson, EK; Magee, WD; Oliver, RD; Tofovic, SP | 1 |
| Henschel, L; Hoffmann, A; Jorke, D; Rechenbach, C; Reinhardt, M | 1 |
| Imai, S; Matsui, K; Ogawa, Y | 1 |
| Greengard, P; Quinn, GP; Reid, MB | 1 |
| Balazs, T; Robinson, CJ | 1 |
| Traub, O; Webb, RC | 1 |
| Kuan, CJ; Tarng, JL; Tseng, CJ; Tung, CS | 1 |
| Kemi, M; Matsumoto, H; Nomura, Y; Takahashi, R | 1 |
| Jackson, EK; Kusaka, H; Pfeifer, CA; Tofovic, SP | 1 |
| Nasu, T; Shibata, H; Yanagimoto, S | 1 |
| Campos-Toimil, M; Estévez, I; Orallo, F; Raviña, E | 1 |
| Aklillu, E; Altman, RB; Boukouvala, S; Hein, DW; Klein, TE; McDonagh, EM | 1 |
2 review(s) available for hydralazine and caffeine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
PharmGKB summary: very important pharmacogene information for N-acetyltransferase 2.
Topics: Alleles; Arylamine N-Acetyltransferase; Caffeine; Gene Expression Profiling; Genomics; Genotype; Humans; Hydralazine; Isoenzymes; Isoniazid; Pharmacogenetics; Phenotype; Polymorphism, Genetic; Sulfamethoxazole; Sulfasalazine; Xenobiotics | 2014 |
20 other study(ies) available for hydralazine and caffeine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Caffeine potentiates vasodilator-induced renin release.
Topics: Adenosine; Analysis of Variance; Animals; Blood Pressure; Caffeine; Chromatography, High Pressure Liquid; Drug Synergism; Hydralazine; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Renin; Xanthines | 1991 |
[Biotransformation in patients following Depressan-induced hepatitis].
Topics: Adult; Aged; Biotransformation; Caffeine; Chemical and Drug Induced Liver Injury; Dihydralazine; Female; Follow-Up Studies; Humans; Hydralazine; Liver Function Tests; Male; Middle Aged; Sulfamethazine | 1989 |
Relaxant effects of pinacidil, nicorandil, hydralazine and nifedipine as studied in the porcine coronary artery and guinea-pig taenia coli.
Topics: Animals; Caffeine; Colon; Coronary Vessels; Female; Guanidines; Guinea Pigs; Hydralazine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium; Swine; Vasodilator Agents | 1986 |
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine | 1966 |
Drug-induced antinuclear antibodies in the guinea pig.
Topics: Acetanilides; Animals; Antibodies, Antinuclear; Antibody Formation; Caffeine; Guinea Pigs; Hydralazine; Male; Procainamide | 1982 |
Angiotensin-converting enzyme inhibition during development alters calcium regulation in adult hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Caffeine; Calcium; Calcium Channels; Cell Membrane; Disease Models, Animal; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Muscle Contraction; Muscle, Smooth, Vascular; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sarcoplasmic Reticulum | 1993 |
Effect of adenosine blockade on plasma renin activity and catecholamines.
Topics: Adenosine; Animals; Blood Pressure; Caffeine; Consciousness; Epinephrine; Hydralazine; Kidney; Male; Norepinephrine; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Renin; Renin-Angiotensin System; Secretory Rate; Sodium, Dietary; Theophylline; Xanthines | 1993 |
Early myocardial lesions induced by cardiotoxic compounds in Sprague-Dawley rats.
Topics: Animals; Caffeine; Cyclophosphamide; Doxorubicin; Heart; Hydralazine; Isoproterenol; Lethal Dose 50; Male; Myocardial Contraction; Myocardium; Rats; Rats, Sprague-Dawley | 1996 |
Central effects of caffeine on renal renin secretion and norepinephrine spillover.
Topics: Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Hydralazine; Injections, Intraventricular; Kidney; Male; Norepinephrine; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Renin; Vasodilator Agents; Xanthines | 1996 |
Effects of hydralazine on responses to histamine and caffeine in ileal longitudinal muscle and taenia coli of the guinea pig.
Topics: Animals; Caffeine; Calcium; Calcium Channels; Colon; Guinea Pigs; Histamine; Hydralazine; Ileum; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth | 1997 |
Pyridazine derivatives XIV. Study of the vasorelaxant action of 6-aryl-5-piperidino-3-hydrazinopyridazines in isolated rat thoracic aorta: comparison with hydralazine.
Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Hydralazine; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Pyridazines; Rats; Rats, Inbred WKY; Structure-Activity Relationship; Vasodilator Agents | 1998 |