Compounds > hydralazine

hydralazine and avapro

hydralazine has been researched along with avapro in 8 studies

Research

Studies (8)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (50.00)	29.6817
2010's	4 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Cody, RJ; Goetze, S; Graf, K; Hsueh, WA; Kawano, H; Kawano, Y; Law, RE; Schnee, J	1
Böhm, M; Czech, T; Fleming, I; Nickenig, G; van Eickels, M; Wassmann, S	1
Baumhäkel, M; Böhm, M; Custodis, F; Laufs, U; Schlimmer, N	1
Dong, YF; Ichijo, H; Kataoka, K; Kim-Mitsuyama, S; Koibuchi, N; Nako, H; Ogawa, H; Toyama, K; Yamamoto, E; Yasuda, O	1
Haruna, Y; Ihoriya, C; Kadoya, H; Kashihara, N; Nagasu, H; Sasaki, T; Satoh, M	1

Reviews

1 review(s) available for hydralazine and avapro

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

7 other study(ies) available for hydralazine and avapro

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Angiotensin II enhances integrin and alpha-actinin expression in adult rat cardiac fibroblasts. Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 2 Topics: Actinin; Age Factors; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antigens, CD; Antihypertensive Agents; Biphenyl Compounds; Cardiomegaly; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Collagen; Fibroblasts; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression; Heart Ventricles; Hydralazine; Imidazoles; Integrin alphaV; Integrin beta Chains; Integrin beta1; Integrin beta3; Integrins; Irbesartan; Laminin; Losartan; Myocardium; Phosphorylation; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Up-Regulation; Vitronectin	2000
Inhibition of diet-induced atherosclerosis and endothelial dysfunction in apolipoprotein E/angiotensin II type 1A receptor double-knockout mice. Circulation, 2004, Nov-09, Volume: 110, Issue:19 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Diseases; Apolipoproteins E; Arteriosclerosis; Biphenyl Compounds; Cholesterol, Dietary; Diet, Atherogenic; Genetic Predisposition to Disease; Hemodynamics; Hydralazine; Hyperlipoproteinemia Type II; Irbesartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Angiotensin, Type 1; Renin; Superoxides; Tetrazoles; Vasoconstriction	2004
Improvement of endothelial function of the corpus cavernosum in apolipoprotein E knockout mice treated with irbesartan. The Journal of pharmacology and experimental therapeutics, 2008, Volume: 327, Issue:3 Topics: Animals; Aorta; Apolipoproteins E; Biphenyl Compounds; Blood Pressure; Endothelium; Endothelium, Vascular; Hydralazine; Irbesartan; Male; Mice; Mice, Knockout; Nitric Oxide; Oxidative Stress; Penile Erection; Penis; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles	2008
Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats: the critical role of ASK1 and VEGF. Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:2 Topics: Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Biphenyl Compounds; Blood Pressure; Blotting, Western; Capillaries; Cells, Cultured; Cyclic N-Oxides; Endothelial Cells; Heart Diseases; Hydralazine; Hypertension; Hypertrophy, Left Ventricular; Immunohistochemistry; Irbesartan; MAP Kinase Kinase Kinase 5; Myocardial Ischemia; Oxidative Stress; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Spin Labels; Superoxides; Tetrazoles; Ultrasonography; Vascular Endothelial Growth Factor A	2012
Hypertension promotes islet morphological changes with vascular injury on pre-diabetic status in SHRsp rats. Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:3 Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Hydralazine; Hypertension; Irbesartan; Islets of Langerhans; Male; Prediabetic State; Rats, Inbred SHR; Tetrazoles; Vascular System Injuries	2014