hydralazine has been researched along with angiotensin ii in 149 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 49 (32.89) | 18.7374 |
| 1990's | 37 (24.83) | 18.2507 |
| 2000's | 40 (26.85) | 29.6817 |
| 2010's | 21 (14.09) | 24.3611 |
| 2020's | 2 (1.34) | 2.80 |
| Authors | Studies |
|---|---|
| DeStevens, G; Wilhelm, M | 1 |
| Nies, AS | 1 |
| Gifford, RW; Tarazi, RC; Wollam, GL | 1 |
| Ashbrook, DW; Purdy, RE | 1 |
| Gant, NF; MacDonald, PC; Madden, JD; Siiteri, PK | 1 |
| Bing, J; Poulsen, K | 1 |
| Keeton, K; Pettinger, WA | 1 |
| Wilcox, RG | 1 |
| Becker, CE; Benowitz, NL | 1 |
| Gerold, M; Haeusler, G | 1 |
| Bowen, PD; Bowman, RL; Chimosky, JE; Holloway, GA; Keiser, HR; Lappe, DL; Stern, MD | 1 |
| Alexandre, JM; Corvol, P; Meignan, M; Ménard, J | 1 |
| Graham, RM; Oates, HF; Stokes, GS | 1 |
| Kajiwara, N | 1 |
| Brooks, SN; Campbell, WB; Keeton, K; Pettinger, WA | 1 |
| Higaki, J; Mikami, H; Morishita, R; Nagano, M; Nakamura, F; Ogihara, T; Tomita, N; Yu, H | 1 |
| Blanc, J; Deckert, V; Elghozi, JL; Grichois, ML | 1 |
| Barnard, JM; Henry, JB; Pedron, SL; Phernetton, TM; Rankin, JH; Reid, DL | 1 |
| Higaki, J; Higashimori, K; Mikami, H; Nagano, M; Nagano, N; Nakamura, F; Ogihara, T | 1 |
| Allen, J; Forman, A; Maigaard, S; Skajaa, K | 1 |
| Fogo, A; Ichikawa, I; Yared, A; Yoshida, Y | 1 |
| Ganten, D; Hellmann, T; Keuneke, C; Metzger, R; Peters, J; Yacullo, R | 1 |
| Bompart, F; Graham, BR; Liu, JB; Prichard, BN; Tomlinson, B | 1 |
| Higashio, T; Kuroda, K | 1 |
| Chestnut, D; Farley, D; Herrig, J; Van Orden, D; Wang, J; Wang, L; Weiner, CP | 1 |
| Kurz, K; Paget, CJ; Ruffolo, RR | 1 |
| Nagao, T; Nakajima, H; Narita, H; Yamaguchi, I | 1 |
| Minami, M; Morii, K; Nomura, A; Saito, H; Saito, I; Sano, M; Togashi, H; Yoshioka, M | 1 |
| Fournier, A; Lagrue, G; Schmitt, H | 1 |
| Fasy, TM; McGiff, JC | 1 |
| Bourgoignie, J; Perry, HM; Schoepfle, E | 1 |
| Gautieri, RF; Ward, CO | 2 |
| Fisher, JW; Malgor, LA | 1 |
| Cummings, JR; Grace, JL; Gray, WD; Welter, AN | 1 |
| Assali, NS; Brinkman, CR; Ladner, C; Weston, P | 1 |
| Snow, JB; Suga, F | 1 |
| Cohn, JN; Tristani, FE | 1 |
| Tanz, RD | 1 |
| Grant, AM; Wales, JK; Wolff, FW | 1 |
| Beilin, LJ; Goldby, FS | 2 |
| Palkoski, Z; Pettinger, W; Renyi, E; Sheppard, H | 1 |
| Bumpus, FM; Khairallah, PA; Sen, S; Tarazi, RC | 1 |
| Branche, G; Chiles, B; Garnier, C; Kilcoyne, MM; Soland, T; Thomson, GE; Williams, M | 1 |
| Kilcoyne, MM | 1 |
| Bellin, H; Börner, H; Dührkop, G; Jung, D; Rostock, G; Teichmann, G | 1 |
| Fyhrquist, F; Grönhagen-Riska, C; Karlberg, BE; Ohman, KP; Tikkanen, I | 1 |
| Chesley, LC | 1 |
| Kawashima, K; Sokabe, H; Watanabe, TX | 1 |
| Cole, FE; MacPhee, AA; Trippodo, NC | 1 |
| Hiramatsu, K; Kubota, T; Yamada, T; Yamagishi, F | 1 |
| Cooper, MJ; Mirkin, BL; Sinaiko, AR | 1 |
| Antonaccio, MJ; Horovitz, ZP; Rubin, B | 1 |
| DiNicolantonio, R; Hutchinson, JS; Mendelsohn, FA | 1 |
| Falch, DK; Norman, N; Sundsfjord, JA | 1 |
| Abassi, ZA; Cuda, G; Golomb, E; Keiser, HR; Panchal, VR; Stylianou, M; Trachewsky, D | 1 |
| Hajj-Ali, AF; Reilly, TM; Wong, PC | 1 |
| Higaki, J; Mikami, H; Morishita, R; Ogihara, T; Rakugi, H; Yu, H | 1 |
| Kadowaki, T; Kojima, M; Komuro, I; Mizuno, T; Shiojima, I; Tobe, K; Ueki, K; Wang, Y; Yamazaki, T; Zou, Z | 1 |
| Brecher, P; Chobanian, AV; Crawford, DC; Himeno, H; Hosoi, M | 1 |
| Soltis, EE | 1 |
| Higaki, J; Kohara, K; Mikami, H; Ogihara, T; Okuda, N | 1 |
| Lloyd, MC; Traub, O; Webb, RC | 1 |
| Aoki, M; Higaki, J; Moriguchi, A; Morishita, R; Nakamura, Y; Rakugi, H; Tomita, N; Tomita, S; Yamada, K; Yu, H | 1 |
| Baxter, LT; Boucher, Y; Jain, RK; Zlotecki, RA | 1 |
| Brink, M; Delafontaine, P; Wellen, J | 1 |
| Cosín Aguilar, J; Cruz Fernández, JM; de Teresa Galván, E; Ferreira Montero, IJ; López-Sendón, J; Soler Soler, J; Tamargo Menéndez, J | 1 |
| Frohlich, ED; Nuñez, E; Prakash, O; Susic, D | 1 |
| Häggström, J; Hansson, K; Karlberg, BE; Kvart, C; Madej, A; Olsson, K | 1 |
| Lao, X; Nalcioglu, O; Roth, GM; Samoszuk, MK; Su, MY; Wang, Z | 1 |
| Capers, Q; de Leon, H; Fukui, T; Griendling, KK; Harrison, DG; Ishizaka, N; Laursen, JB; Rajagopalan, S; Taylor, WR; Wilcox, JN | 1 |
| Alexander, RW; Capers, Q; De Leon, H; Howard, AB; Ishizaka, N; Lou, P; Taylor, WR; Wilcox, JN | 1 |
| Andoh, TF; Bennett, WM; Couser, WG; Johnson, RJ; Pichler, RH; Shankland, SJ; Thomas, SE | 1 |
| Cassis, LA; Fettinger, MJ; Lodder, RA; Marshall, DE; Rosenbluth, B | 1 |
| Lombardi, DM; Schwartz, SM; Siegal, J; Su, EJ | 1 |
| Böhm, M; Buikema, H; Flesch, M; Paul, M; Pinto, YM; Teisman, AC; van Gilst, WH | 1 |
| Fukamizu, A; Ishikawa, K; Kai, T; Kurooka, A; Murakami, K; Shimada, S; Sugimura, K; Takenaka, T | 1 |
| Kawachi, H; Kimura, H; Nakamura, T; Obata, J; Ohno, S; Shimizu, F; Yoshida, Y | 1 |
| Ferrario, CM; Gallagher, PE; Ganten, D; Strawn, WB; Tallant, EA | 1 |
| Yamazaki, T; Yazaki, Y | 1 |
| Ishikawa, K; Kai, T; Kurooka, A; Shimada, S; Sugimura, K | 1 |
| Higaki, J; Matsumoto, K; Moriguchi, A; Morishita, R; Nakamura, T; Nishii, T; Ogihara, T; Tomita, N; Yo, Y | 1 |
| Al-Nimri, MA; Anderson, S; Chapman, JG; Kelly, FJ; Kennefick, TM; Oyama, TT; Thompson, MM | 1 |
| Aizawa, T; Ishizaka, N; Nagai, R; Nakao, A; Ohishi, N; Ohno, M; Shimizu, T; Suzuki, M; Taguchi, J | 1 |
| Cody, RJ; Goetze, S; Graf, K; Hsueh, WA; Kawano, H; Kawano, Y; Law, RE; Schnee, J | 1 |
| Bader, M; Breu, V; Ganten, D; Gross, V; Haller, H; Luft, FC; Mervaala, E; Müller, DN; Park, JK; Schmidt, F | 1 |
| Aizawa, T; Ingelfinger, JR; Ishizaka, N; Mori, I; Nagai, R; Ohno, M; Taguchi, Ji; Tang, SS | 1 |
| Komuro, I; Yamazaki, T; Yazaki, Y | 1 |
| Aizawa, T; Ishizaka, N; Mori, I; Nagai, R; Ohno, M; Taguchi, J; Yazaki, Y | 1 |
| Breu, V; Dechend, R; Ganten, D; Genersch, E; Haller, H; Löffler, BM; Luft, FC; Mervaala, EM; Muller, DN; Park, JK; Schmidt, F; Schneider, W | 1 |
| Guo, DF; Inagami, T; Kimura, H; Naito, A; Nakamura, T; Obata, J; Shimizu, F; Takano, H; Yoshida, Y | 1 |
| Abe, I; Fujii, K; Fujishima, M; Goto, K; Onaka, U | 1 |
| Caplea, A; Daneshvar, H; Dunphy, G; Ely, D; Milsted, A; Seachrist, D | 1 |
| Keen, HL; Sigmund, CD | 1 |
| Hayashi, M; Nakaya, H; Saruta, T; Sasamura, H | 1 |
| Adams, MA; Hale, TM; Heaton, JP; Okabe, H | 1 |
| Paull, JR; Widdop, RE | 1 |
| Cardin, S; Leung, TK; Li, D; Nattel, S; Pang, L; Shinagawa, K; Wang, Z | 1 |
| Higaki, J; Kamide, K; Moriguchi, K; Nagai, M; Ogihara, T; Ohishi, M; Okamura, A; Rakugi, H; Satoh, N; Tuck, ML | 1 |
| Ehmke, H; Faulhaber, J; Moser, L; Wiesner, RJ | 1 |
| de Denus, S; Spinler, SA | 1 |
| Cheon, HW; Choi, JH; Hong, YS; Kim, CH; Kim, KB; Kim, SK; Lee, JW; Yoo, KH | 1 |
| Gould, PA; Kaye, DM | 1 |
| Neves, MF; Schiffrin, EL; Virdis, A | 1 |
| Brooks, VL; McKeogh, DF; O'Donaughy, TL | 1 |
| Amiri, F; Neves, MF; Schiffrin, EL; Touyz, RM; Virdis, A | 1 |
| Cook, AK; Imig, JD; Inscho, EW; Murzynowski, JB | 1 |
| Blaak, EE; Goossens, GH; Saris, WH; van Baak, MA | 1 |
| Chen, Y; Currie, RW; Ross, BM | 1 |
| Abe, Y; Kimura, S; Kiyomoto, H; Kobori, H; Kohno, M; Miyata, K; Miyatake, A; Nagai, Y; Nishiyama, A; Ozawa, Y; Shokoji, T; Yao, L; Yukimura, T | 1 |
| Ferrario, CM; Gallagher, PE; Geary, RL; Igase, M; Strawn, WB | 1 |
| Amiri, F; Brassard, P; Schiffrin, EL | 1 |
| Hashimoto, T; Imai, N; Kihara, M; Sato, K; Toya, Y; Umemura, S | 1 |
| Amiri, F; Brassard, P; Schiffrin, EL; Thibault, G | 1 |
| Akasaka, T; Imanishi, T; Kobayashi, K | 1 |
| Ishizaka, N; Matsuzaki, G; Mori, I; Nagai, R; Noiri, E; Saito, K | 1 |
| Akasaka, T; Goto, M; Imanishi, T; Kobayashi, K; Kuroi, A; Mochizuki, S; Yoshida, K | 1 |
| Pandey, KN; Somanna, N; Vellaichamy, E; Zhao, D | 1 |
| Ayabe, N; Babaev, VR; Fazio, S; Fogo, AB; Ichikawa, I; Kon, V; Linton, MF; Motojima, M; Suganuma, E; Zuo, Y | 1 |
| Delbosc, S; Jover, B; Mimran, A; Rugale, C | 1 |
| Ishikawa, K; Kamiyama, Y; Kimura, S; Kobayashi, A; Maruyama, Y; Matsumoto, H | 1 |
| Dong, YF; Ichijo, H; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Ogawa, H; Shintaku, H; Tokutomi, Y; Yamamoto, E; Yamashita, T | 1 |
| Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Nakamura, T; Ogawa, H; Tamamaki, N; Tokutomi, Y; Yamamoto, E | 1 |
| Cassis, LA; Charnigo, R; Daugherty, A; Gupte, M; Howatt, DA; Rateri, DL; Thayer, S; Zhang, X | 1 |
| Agharazii, M; Bélanger, S; Larivière, R; Lebel, M; Lemieux, P; Therrien, F | 1 |
| Baron-Menguy, C; Cousin, M; Custaud, MA; Dumont, O; Guihot, AL; Henrion, D; Loufrani, L; Subra, JF; Toutain, B; Vessières, E | 1 |
| Gordon, FJ; Guzik, TJ; Harrison, DG; Lob, HE; Marvar, PJ; McCann, LA; Thabet, SR; Weyand, C | 1 |
| Casarini, DE; Coelho, MS; Ferreira, DN; Furukawa, LN; Heimann, JC; Katayama, IA; Oliveira, IB; Rosa, KT | 1 |
| Chen, R; Eisner, C; Hu, X; Huang, Y; Kopp, JB; Leelahavanichkul, A; Mizel, D; Schnermann, J; Star, RA; Wright, EC; Yan, Q; Yuen, PS; Zhou, H | 1 |
| d'Uscio, LV; Kang, KT; Katusic, ZS; Pollock, JS; Spradley, FT; Sullivan, JC | 1 |
| Lin, JY; Moens, AL | 1 |
| Al-Saleh, FM; Benter, IF; Chappell, MC; Diz, DI; Raghupathy, R; Yousif, MH | 1 |
| Bian, Y; Cheng, J; Du, J; Jia, L; Li, H; Li, Y; Qi, G; Xiao, C | 1 |
| Dong, YF; Ichijo, H; Kataoka, K; Kim-Mitsuyama, S; Koibuchi, N; Nako, H; Ogawa, H; Toyama, K; Yamamoto, E; Yasuda, O | 1 |
| Deguchi, K; Hitomi, H; Kitada, K; Kobori, H; Lei, B; Masaki, T; Minamino, T; Mori, H; Nakano, D; Nishiyama, A | 1 |
| Fujigaki, Y; Fukasawa, H; Hishida, A; Huang, Y; Ichihara, A; Ikegaya, N; Misaki, T; Nishiyama, A; Ohashi, N; Senbonmatsu, T; Suzuki, H; Togawa, A; Yamamoto, T | 1 |
| Ascione, R; Dominiczak, AF; Giannotta, M; Graham, D; Hendy, EB; Hewinson, J; Kasparov, S; Liu, B; McBride, F; Oliveira-Sales, EB; Paton, JF; Toward, M; Waki, H; Xu, H | 1 |
| Bartlett, CS; Boyd, KL; Breyer, RM; Harris, RC; Zent, R | 1 |
| Becher, PM; Fröhlich, M; Hoffmann, S; Lindner, D; Savvatis, K; Schultheiss, HP; Tschöpe, C; Westermann, D; Xia, Y | 1 |
| Ayuzawa, N; Fujita, T; Ishizawa, K; Kawarazaki, W; Nagase, M; Takeuchi, M; Ueda, K; Yoshida, S | 1 |
| Horio, T; Kangawa, K; Kawano, Y; Kishimoto, I; Kuwabara, A; Otani, K; Tokudome, T; Yoshihara, F | 1 |
| Dopona, EP; Furukawa, LN; Heimann, JC; Katayama, IA; Oliveira, IB; Pereira, RC; Shimizu, MH | 1 |
| Cheng, XW; Hamrah, MS; Hao, CN; Hayashi, M; Hu, L; Kuzuya, M; Murohara, T; Shi, GP; Takeshita, K; Wu, H | 1 |
| Fujigaki, Y; Ishigaki, S; Isobe, S; Kato, A; Miyajima, H; Nishiyama, A; Ohashi, N; Sakao, Y; Tsuji, T; Yasuda, H | 1 |
| Adhikari, S; Alpert, L; Bissonnette, M; Chen, L; Deb, DK; Dougherty, U; Hart, J; He, L; Kwon, J; Li, YC; Liu, SQ; Liu, T; Liu, W; Pekow, J; Rubin, DT; Shi, Y; Wang, J; Zhao, Q; Zhou, G | 1 |
| Boult, JK; Collins, DJ; d'Arcy, J; Jerome, NP; Koh, DM; Leach, MO; Orton, MR; Robinson, SP | 1 |
| Bishop, NM; Cipolla, MJ; Li, Z; Lindner, DP | 1 |
| Fujita, Y; Hoshino, S; Ichikawa, D; Inoue, K; Kamijo-Ikemori, A; Kimura, K; Ohata, K; Shibagaki, Y; Sugaya, T; Tanabe, J; Togo, T; Watanabe, M | 1 |
9 review(s) available for hydralazine and angiotensin ii
| Article | Year |
|---|---|
Antihypertensive agents.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Blood Vessels; Clonidine; Diuretics; Drug Therapy, Combination; Ganglionic Blockers; Guanethidine; History, 20th Century; Hydralazine; Methyldopa; Monoamine Oxidase Inhibitors; Muscle, Smooth; Renin; Reserpine; Sympathetic Nervous System; Vasodilator Agents; Water-Electrolyte Balance | 1976 |
Clinical pharmacology of antihypertensive drugs.
Topics: Adrenergic alpha-Antagonists; Aldosterone; Angiotensin II; Antihypertensive Agents; Bethanidine; Blood Pressure; Clonidine; Diazoxide; Diuretics; Emergencies; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Monoamine Oxidase Inhibitors; Nitroprusside; Prazosin; Propranolol; Renin; Reserpine; Sympathetic Nervous System; Trimethaphan | 1977 |
Antihypertensive drugs: clinical pharmacology and therapeutic use.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Humans; Hydralazine; Hypertension; Labetalol; Methyldopa; Minoxidil; Monoamine Oxidase Inhibitors; Nitroprusside; Potassium; Prazosin; Secologanin Tryptamine Alkaloids; Sympatholytics | 1977 |
The control of hypertension in pregnancy.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Diazoxide; Diuretics; Eclampsia; Female; Homeostasis; Humans; Hydralazine; Hypertension; Methyldopa; Nitroprusside; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Prostaglandins E; Regional Blood Flow; Secologanin Tryptamine Alkaloids; Veratrum Alkaloids | 1981 |
Effects of captopril in animal models of hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Animals; Arteries; Blood Pressure; Bradykinin; Captopril; Dogs; Hemodynamics; Hydralazine; Hydrochlorothiazide; Hypertension; Kallikreins; Kidney; Proline; Prostaglandins; Rabbits; Rats; Renin; Sodium | 1980 |
[Neurohormonal factors in heart failure. I].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Autonomic Nervous System; Clinical Trials as Topic; Female; Heart; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Male; Middle Aged; Receptors, Adrenergic; Renin-Angiotensin System; Vasodilator Agents | 1996 |
Role of tissue angiotensin II in myocardial remodelling induced by mechanical stress.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Hydralazine; Hypertension; Myocardium; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Stress, Mechanical; Tetrazoles; Ventricular Remodeling | 1999 |
Role of the renin-angiotensin system in cardiac hypertrophy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cardiomegaly; Cell Division; Cells, Cultured; Hydralazine; Hypertension; Mitogen-Activated Protein Kinases; Myocardium; Protein-Tyrosine Kinases; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction; Sodium-Hydrogen Exchangers; Tetrazoles | 1999 |
Clinical treatment regimens for chronic heart failure: a review.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Cardiotonic Agents; Digoxin; Diuretics; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Pacemaker, Artificial; Spironolactone; Vasodilator Agents | 2002 |
4 trial(s) available for hydralazine and angiotensin ii
| Article | Year |
|---|---|
Combination hypotensive therapy with atenolol, bendrofluazide and hydrallazine.
Topics: Angiotensin II; Atenolol; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Male; Propanolamines; Renin | 1977 |
Vasodilating mechanism and response to physiological pressor stimuli of acute doses of carvedilol compared with labetalol, propranolol and hydralazine.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Cold Temperature; Double-Blind Method; Exercise; Heart Rate; Hemodynamics; Humans; Hydralazine; Isoproterenol; Labetalol; Male; Middle Aged; Phenylephrine; Posture; Propanolamines; Propranolol; Vasodilator Agents | 1988 |
Enalapril and lisinopril in renovascular hypertension--antihypertensive and hormonal effects of two new angiotensin-converting-enzyme (ACE) inhibitors. A preliminary report.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Dipeptides; Enalapril; Humans; Hydralazine; Hypertension, Renovascular; Lisinopril; Middle Aged; Prazosin | 1984 |
Angiotensin II-induced effects on adipose and skeletal muscle tissue blood flow and lipolysis in normal-weight and obese subjects.
Topics: Adipose Tissue; Angiotensin II; Body Weight; Central Nervous System Depressants; Drug Interactions; Ethanol; Glycerol; Humans; Hydralazine; Lipolysis; Male; Microdialysis; Middle Aged; Muscle, Skeletal; Obesity; Regional Blood Flow; Vasoconstrictor Agents; Vasodilator Agents | 2004 |
136 other study(ies) available for hydralazine and angiotensin ii
| Article | Year |
|---|---|
The evaluation of cardiovascular drugs in the anaesthetized, unrestrained rat.
Topics: Angiotensin II; Animals; Blood Pressure; Catheterization; Clonidine; Hydralazine; Jugular Veins; Male; Mecamylamine; Myocardium; Norepinephrine; Rats | 1978 |
The metabolic clearance rate of dehydroisoandrosterone sulfate. IV. Acute effects of induced hypertension, hypotension, and naturesis in normal and hypertensive pregnancies.
Topics: Adult; Angiotensin II; Blood Pressure; Dehydroepiandrosterone; Female; Furosemide; Humans; Hydralazine; Hypertension; Hypotension; Metabolic Clearance Rate; Muscle, Smooth; Pregnancy; Pregnancy Complications, Cardiovascular | 1976 |
Time course of changes in plasma renin after blockade of the renin-system. Studies of conscious and anaesthetized, normal, adrenalectomized and spontaneously hypertensive rats.
Topics: Adrenalectomy; Anesthesia; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Depression, Chemical; Desoxycorticosterone; Female; Hydralazine; Hypertension; Juxtaglomerular Apparatus; Oligopeptides; Rats; Renin; Saralasin; Sodium Chloride; Stimulation, Chemical; Teprotide; Time Factors | 1975 |
Altered renin release and propranolol potentiation of vasodilatory drug hypotension.
Topics: Angiotensin II; Animals; Blood Pressure; Central Nervous System; Depression, Chemical; Dose-Response Relationship, Drug; Drug Synergism; Heart Rate; Hemodynamics; Hydralazine; Hypotension; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Minoxidil; Nephrectomy; Propranolol; Rats; Renin; Tachycardia; Vasodilator Agents | 1975 |
Hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Brain Diseases; Cerebrovascular Disorders; Diazoxide; Dogs; Emergencies; Female; Heart Diseases; Humans; Hydralazine; Hypertension; Methyldopa; Nitroprusside; Pheochromocytoma; Pre-Eclampsia; Pregnancy; Reserpine; Trimethaphan | 1979 |
Increased levels of prostaglandin-like material in the canine blood during arterial hypotension produced by hydralazine, dihydralazine and minoxidil.
Topics: Angiotensin II; Animals; Blood Pressure; Dihydralazine; Dogs; Female; Guinea Pigs; Hydralazine; Hypotension; Indomethacin; Male; Minoxidil; Prostaglandins; Pyrimidines; Rabbits; Species Specificity; Time Factors | 1979 |
Continuous measurement of tissue blood flow by laser-Doppler spectroscopy.
Topics: Adult; Angiotensin II; Animals; Dopamine; Doppler Effect; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Hydralazine; Isoproterenol; Kidney Cortex; Lasers; Male; Methods; Nitroprusside; Norepinephrine; Rats; Regional Blood Flow; Saralasin; Scattering, Radiation; Skin; Xenon Radioisotopes | 1977 |
[Equilibration of the treatment of severe arterial hypertension. Significance of d-1 propranolol].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Heart Rate; Humans; Hydralazine; Hypertension; Long-Term Care; Propranolol; Pulse; Renin | 1975 |
Mechanism of the hypotensive action of prazosin.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diazoxide; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; Heart Rate; Hydralazine; Indoramin; Norepinephrine; Pentolinium Tartrate; Phentolamine; Prazosin; Quinazolines; Rats | 1977 |
Therapy and prognosis of hypertension in chronic nephritis.
Topics: Adult; Aldosterone; Angiotensin II; Blood Volume; Catecholamines; Chronic Disease; Creatinine; Extracellular Space; Female; Glomerulonephritis; Humans; Hydralazine; Hypertension; Hypertension, Renal; Male; Methyldopa; Middle Aged; Prognosis; Propranolol | 1975 |
Vasodilating antihypertensive drug-induced aldosterone release--a study of endogenous angiotensin-mediated aldosterone release in the rat.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Corticosterone; Hydralazine; Hypophysectomy; Kidney; Male; Minoxidil; Nephrectomy; Pituitary Gland; Propranolol; Rats; Renin; Saralasin; Vasodilator Agents | 1975 |
Regression of hypertension-induced vascular hypertrophy by an ACE inhibitor and calcium antagonist in the spontaneously hypertensive rat.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Abdominal; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Hydralazine; Hypertension; Hypertrophy; Indans; Male; Nitrobenzenes; Piperazines; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 1992 |
Differential effects of enalapril and hydralazine on short-term variability of blood pressure and heart rate in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Drinking Behavior; Enalapril; Heart Rate; Hydralazine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Renin-Angiotensin System | 1992 |
Differential effects of intravenous hydralazine on myoendometrial and placental blood flow in hypertensive pregnant ewes.
Topics: Adrenal Glands; Angiotensin II; Animals; Endometrium; Female; Hydralazine; Hypertension; Injections, Intravenous; Microspheres; Myometrium; Placenta; Pregnancy; Regional Blood Flow; Renal Circulation; Sheep; Vascular Resistance | 1992 |
Role of cardiac angiotensin II in isoproterenol-induced left ventricular hypertrophy.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Cardiomegaly; Heart Rate; Hydralazine; Indoles; Isoproterenol; Male; Myocardium; Nephrectomy; Rats; Rats, Inbred Strains; Renin | 1992 |
Effects of vasodilators on isolated human uteroplacental arteries.
Topics: Angiotensin II; Arteries; Chorionic Villi; Dinoprost; Female; Humans; Hydralazine; Labetalol; Nitrendipine; Norepinephrine; Potassium; Prazosin; Pregnancy; Uterus; Vasoconstriction; Vasodilator Agents; Vasopressins | 1991 |
Importance of angiogenic action of angiotensin II in the glomerular growth of maturing kidneys.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Enalapril; Hydralazine; Kidney Glomerulus; Male; Rats; Verapamil | 1990 |
The role of tissue renin-angiotensin systems in hypertension and effects of chronic converting-enzyme inhibition.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Captopril; Enalapril; Gene Expression Regulation; Heart; Hydralazine; Hypertension; Isoquinolines; Kidney; Lisinopril; Male; Quinapril; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrahydroisoquinolines | 1990 |
Effects of cadralazine on contractions induced by norepinephrine, serotonin, angiotensin II and K+ in rabbit aortic and renal arterial strips.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Hydralazine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Pyridazines; Rabbits; Renal Artery; Serotonin | 1988 |
Chronic measurement, using a Doppler probe, of uterine artery flow in the gravid guinea-pig.
Topics: Angiotensin II; Animals; Blood Flow Velocity; Epinephrine; Female; Guinea Pigs; Hydralazine; Models, Biological; Pregnancy; Pregnancy, Animal; Ultrasonography; Uterus | 1986 |
Evaluation of a novel antihypertensive agent, LY127210, in anesthetized and conscious spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Hydralazine; Hypertension; Male; Rats; Rats, Inbred SHR; Vascular Resistance | 1985 |
Calcium entry blockers: antihypertensive and natriuretic effects in experimental animals.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dogs; Glomerular Filtration Rate; Heart Rate; Hydralazine; Kidney; Natriuresis; Nifedipine; Rana catesbeiana; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Renin-Angiotensin System; Urinary Bladder | 1985 |
[Effects of a new vasodilator, budralazine on water drinking activity, plasma norepinephrine, plasma angiotensin II, plasma arginine vasopressin, plasma serotonin concentration, urinary aldosterone excretion rate and urinary catecholamine excretion rate i
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Arginine Vasopressin; Blood Pressure; Catecholamines; Drinking Behavior; Heart Rate; Hydralazine; Male; Rats; Rats, Inbred WKY; Serotonin | 1985 |
[Pharmacological basis of the symptomatic treatment of arterial hypertension. I. Hemodynamic effects, mechanisms of action and side effects of antihypertensive agents].
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Guanethidine; Hemodynamics; Humans; Hydralazine; Hypertension; Long-Term Care; Medulla Oblongata; Methyldopa; Monoamine Oxidase Inhibitors; Propranolol; Receptors, Adrenergic; Renin; Reserpine; Synaptic Transmission; Vasomotor System | 1973 |
The relationship of the renal vascular activity of angiotensin II to the autonomic nervous system.
Topics: Angiotensin II; Animals; Blood Circulation; Bretylium Compounds; Cordotomy; Denervation; Dogs; Epinephrine; Guanethidine; Hexamethonium Compounds; Hydralazine; Kidney; Nicotinic Acids; Norepinephrine; Phentolamine; Regional Blood Flow; Sympathetic Nervous System; Tyramine | 1965 |
In vitro production and inhibition of aortic vasoconstriction by mercuric, cadmium, and other metal ions.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Cadmium; Cyanides; Edetic Acid; Epinephrine; Ethylmaleimide; Female; Hydralazine; In Vitro Techniques; Ions; Mercury; Metals; Muscle Contraction; Phentolamine; Rabbits; Sulfhydryl Compounds; Vasomotor System | 1967 |
Effect of certain drugs on perfused human placenta. 8. Angiotensin-II antagonists.
Topics: Acetates; Angiotensin II; Atropine; Blood Pressure Determination; Cobalt; Cocaine; Cyproheptadine; Dibenzylchlorethamine; Dipyridamole; Ethanol; Female; Furans; Glycols; Humans; Hydralazine; In Vitro Techniques; Isosorbide Dinitrate; Muscles; Nitrates; Nitrites; Nitroglycerin; Papaverine; Perfusion; Phentolamine; Placenta; Pregnancy; Sodium; Sympatholytics; Tartrates; Tolazoline | 1968 |
Antagonism of angiotensin by hydralazine on renal blood flow and erythropoietin production.
Topics: Angiotensin II; Animals; Blood Flow Velocity; Blood Pressure; Dogs; Drug Synergism; Erythropoietin; Female; Hematocrit; Hydralazine; Kidney; Male; Polycythemia; Renal Artery | 1969 |
Angiotensin blocking actions of guancydine.
Topics: Angiotensin II; Animals; Atropine; Blood Flow Velocity; Blood Pressure; Carotid Arteries; Epinephrine; Guanethidine; Guanidines; Hexamethonium Compounds; Hydralazine; Hypotension; Injections; Kidney; Male; Nephrectomy; Norepinephrine; Phenoxybenzamine; Propranolol; Rats; Renal Artery; Renin; Reserpine | 1969 |
Dynamics of uterine circulation in pregnant and nonpregnant sheep.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Homeostasis; Hydralazine; Injections, Intra-Arterial; Injections, Intravenous; Isoproterenol; Methods; Norepinephrine; Phenoxybenzamine; Pregnancy; Pregnancy, Animal; Regional Blood Flow; Sheep; Uterus; Vascular Resistance | 1970 |
Cochlear blood flow in response to vasodilating drugs and some related agents.
Topics: Amyl Nitrite; Angiotensin II; Animals; Asphyxia; Betahistine; Blood Flow Velocity; Blood Pressure; Bradykinin; Carbon Dioxide; Cochlea; Dipyridamole; Electrocardiography; Guinea Pigs; Histamine; Hydralazine; Hyperventilation; Hypoventilation; Kallidin; Nicotinic Acids; Oxygen; Papaverine; Regional Blood Flow; Tetraethylammonium Compounds; Vasodilator Agents | 1969 |
Studies in clinical shock and hypotension. VII. Renal hemodynamics before and during treatment.
Topics: Acetylcholine; Adult; Aged; Angiotensin II; Blood Flow Velocity; Blood Urea Nitrogen; Cardiac Output; Dextrans; Dopamine; Dye Dilution Technique; Humans; Hydralazine; Hypotension; Isoproterenol; Kidney; Male; Metaraminol; Middle Aged; Norepinephrine; Plasma Substitutes; Regional Blood Flow; Shock; Vascular Resistance; Vasoconstrictor Agents | 1970 |
Evaluation of antihypertensive drugs in dogs with angiotensin-induced hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Disease Models, Animal; Dogs; Female; Hexamethonium Compounds; Hydralazine; Hypertension; Male; Nitrites; Sodium | 1971 |
The effect of tolbutamide on blood pressure.
Topics: Angiotensin II; Animals; Blood Glucose; Blood Pressure; Diazoxide; Diuresis; Dogs; Hydralazine; Insulin; Norepinephrine; Pentolinium Tartrate; Phentolamine; Tolbutamide | 1971 |
Relationship between arterial pressure and the permeability of arterioles to carbon particles in acute hypertension in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Capillary Permeability; Carbon; Constriction; Dilatation; Hydralazine; Kidney; Male; Mesenteric Arteries; Norepinephrine; Rats; Tissue Extracts | 1972 |
How an acute rise in arterial pressure damages arterioles. Electron microscopic changes during angiotensin infusion.
Topics: Angiotensin II; Animals; Arteries; Basement Membrane; Blood Platelets; Capillary Permeability; Carbon; Constriction; Dilatation; Epithelial Cells; Hydralazine; Hypertension; Male; Microscopy, Electron; Muscle, Smooth; Nephrectomy; Rats; Time Factors | 1972 |
Angiotensin antagonism and antihypertensive activity of phosphodiesterase inhibiting agents.
Topics: Adult; Angiotensin II; Animals; Bethanechol Compounds; Blood Pressure; Bradykinin; Bretylium Compounds; Debrisoquin; Diazoxide; Dose-Response Relationship, Drug; Female; Guanethidine; Heart Rate; Humans; Hydralazine; Imidazoles; Male; Norepinephrine; Phenoxybenzamine; Phentolamine; Phosphodiesterase Inhibitors; Rats; Theophylline; Vasodilator Agents | 1973 |
Cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Age Factors; Angiotensin II; Animals; Cardiomegaly; DNA; Heart Ventricles; Hydralazine; Hypertension; Methyldopa; Organ Size; Rats; Rats, Inbred Strains; Renin | 1974 |
Characteristics of hypertension in the black population.
Topics: Adult; Angiotensin II; Animals; Black or African American; Cardiomegaly; Cerebrovascular Disorders; Chlorthalidone; Coronary Disease; Drug Therapy, Combination; Female; Guanethidine; Heart Ventricles; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; New York City; Rabbits; Radioimmunoassay; Renin; Sodium; Spironolactone | 1974 |
Adolescent hypertension. II. Characteristics and response to treatment.
Topics: Adolescent; Adult; Angiotensin II; Black or African American; Female; Humans; Hydralazine; Hypertension; Kidney; Latin America; Male; Mass Screening; Methyldopa; New York City; Propranolol; Radioimmunoassay; Renin; Sodium; Spironolactone | 1974 |
[Hemodynamic regulation of the heart in hypertension under intravenous administration of dihydralazine].
Topics: Angiotensin II; Blood Pressure; Heart; Heart Rate; Hemodynamics; Humans; Hydralazine; Hypertension; Injections, Intravenous; Kinins; Renin | 1974 |
Effect of certain drugs on perfused human placenta. IX. Mode of action of angiotensin.
Topics: Angiotensin II; Blood Vessels; Constriction; Dipyridamole; Ethanolamines; Female; Humans; Hydralazine; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Nitrites; Nitroglycerin; Perfusion; Phenoxybenzamine; Phentolamine; Placenta; Pregnancy; Tolazoline | 1969 |
Pharmacodynamic and pharmacokinetic studies on prizidilol and nipradilol (K-351), antihypertensive drugs with combined vasodilator and beta-adrenoceptor blocking actions, in rabbits.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hydralazine; Isoproterenol; Kinetics; Male; Propanolamines; Propranolol; Pyridazines; Rabbits; Time Factors; Vasodilator Agents | 1984 |
Natriuretic response to atrial natriuretic factor enhanced by angiotensin II and vasopressin.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; Drug Synergism; Epinephrine; Hydralazine; Male; Natriuresis; Norepinephrine; Rats; Rats, Inbred Strains; Saralasin | 1984 |
Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension.
Topics: Adult; Age Factors; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Calcium; Heart Rate; Humans; Hydralazine; Hydrocortisone; Hypertension; Middle Aged; Nifedipine; Peptidyl-Dipeptidase A; Pyridines; Renin; Renin-Angiotensin System | 1982 |
Effect of neonatal sympathectomy with 6-hydroxydopamine on reactivity of the renin-angiotensin system in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Body Weight; Female; Hydralazine; Hydroxydopamines; Hypertension; Male; Norepinephrine; Rats; Renin; Sympathectomy; Sympathetic Nervous System | 1980 |
Exaggerated salt appetite of spontaneously hypertensive rats is decreased by central angiotensin-converting enzyme blockade.
Topics: Angiotensin II; Animals; Appetite; Brain; Captopril; Hydralazine; Hypertension; Injections, Intraventricular; Male; Proline; Rats; Rats, Inbred Strains; Sodium Chloride; Thirst | 1982 |
The influence of dihydralazine and angiotensin-II blockade on renal extraction of [131I]hippuran.
Topics: Adult; Angiotensin II; Dihydralazine; Female; Humans; Hydralazine; Iodohippuric Acid; Kidney; Male; Middle Aged; Radiography; Renal Circulation | 1981 |
Angiotensin II maintains, but does not mediate, isoproterenol-induced cardiac hypertrophy in rats.
Topics: Actins; Angiotensin II; Animals; Base Sequence; Biphenyl Compounds; Blood Pressure; Captopril; Cardiomegaly; DNA; DNA Primers; Dose-Response Relationship, Drug; Gene Expression; Genes, fos; Heart; Hydralazine; Hydroxyproline; Imidazoles; Isoproterenol; Labetalol; Losartan; Male; Methyldopa; Molecular Sequence Data; Myocardium; Myosins; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrazoles; Transcription, Genetic | 1994 |
Modulation of renal vasoconstrictor effect of NG-nitro-L-arginine in rabbit by angiotensin II and alpha-1 adrenergic receptor blockade.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Antibodies; Arginine; Biphenyl Compounds; Drug Interactions; Hemodynamics; Hydralazine; Imidazoles; Kidney; Losartan; Male; Nitroarginine; Prazosin; Rabbits; Tetrazoles; Vasoconstrictor Agents | 1994 |
The role of activated vascular angiotensin II generation in vascular hypertrophy in one-kidney, one clip hypertensive rats.
Topics: Actins; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Benzimidazoles; Biphenyl Compounds; DNA; Hydralazine; Hypertension, Renovascular; Hypertrophy; Indans; Male; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Tetrazoles | 1993 |
Angiotensin II receptor antagonist TCV-116 induces regression of hypertensive left ventricular hypertrophy in vivo and inhibits the intracellular signaling pathway of stretch-mediated cardiomyocyte hypertrophy in vitro.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Hydralazine; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Signal Transduction; Tetrazoles | 1994 |
Angiotensin II alters aortic fibronectin independently of hypertension.
Topics: Angiotensin II; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Fibronectins; Humans; Hydralazine; Hypertension; Imidazoles; Losartan; Male; Prazosin; Rats; Rats, Wistar; RNA, Messenger; Tetrazoles | 1994 |
Alterations in vascular structure and function after short-term losartan treatment in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Hydralazine; Hypertension; Imidazoles; Losartan; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Tetrazoles; Vasoconstriction | 1993 |
Angiotensin blockade and the progression of renal damage in the spontaneously hypertensive rat.
Topics: Albuminuria; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chromatography, High Pressure Liquid; Hydralazine; Hypertension; Indans; Kidney; Male; Proteinuria; Rats; Rats, Inbred SHR; Survival Analysis; Tetrazoles | 1993 |
Long-term effects of brief antihypertensive treatment on systolic blood pressure and vascular reactivity in young genetically hypertensive rats.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Hydralazine; Hydrochlorothiazide; Hypertension; Linear Models; Muscle Contraction; Muscle, Smooth, Vascular; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance | 1995 |
Effect of an antihypertensive drug on brain angiotensin II levels in renal and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brain Chemistry; Chromatography, High Pressure Liquid; Hydralazine; Hypertension; Hypertension, Renovascular; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Renin-Angiotensin System | 1995 |
Pharmacologic modification of tumor blood flow and interstitial fluid pressure in a human tumor xenograft: network analysis and mechanistic interpretation.
Topics: Angiotensin II; Animals; Colonic Neoplasms; Epinephrine; Extracellular Space; Female; Humans; Hydralazine; Mice; Mice, SCID; Models, Theoretical; Neoplasm Transplantation; Nitroglycerin; Norepinephrine; Regional Blood Flow; Transplantation, Heterologous | 1995 |
Angiotensin II causes weight loss and decreases circulating insulin-like growth factor I in rats through a pressor-independent mechanism.
Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Body Weight; Hematocrit; Hydralazine; Hypertension; Imidazoles; Infusions, Intravenous; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor I; Losartan; Male; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Reference Values; Tetrazoles; Time Factors; Vasodilator Agents; Weight Loss | 1996 |
Angiotensin II increases left ventricular mass without affecting myosin isoform mRNAs.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Heart Ventricles; Hemodynamics; Hydralazine; Hypertrophy, Left Ventricular; Imidazoles; Infusion Pumps, Implantable; Losartan; Male; Myosin Heavy Chains; Organ Size; Random Allocation; Rats; Rats, Wistar; RNA, Messenger; Tetrazoles | 1996 |
Effects of long-term treatment with enalapril or hydralazine on the renin-angiotensin-aldosterone system and fluid balance in dogs with naturally acquired mitral valve regurgitation.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Dog Diseases; Dogs; Echocardiography; Enalapril; Female; Furosemide; Heart Failure; Heart Rate; Hydralazine; Male; Mitral Valve Insufficiency; Renin-Angiotensin System; Vasodilator Agents; Water-Electrolyte Balance | 1996 |
Pharmacokinetic changes induced by vasomodulators in kidneys, livers, muscles, and implanted tumors in rats as measured by dynamic Gd-DTPA-enhanced MRI.
Topics: Adenocarcinoma; Angiotensin II; Animals; Blood Flow Velocity; Capillary Permeability; Cell Transplantation; Contrast Media; Female; Gadolinium DTPA; Hydralazine; Kidney; Liver; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Mammary Neoplasms, Experimental; Muscle, Skeletal; Neoplasm Transplantation; Organometallic Compounds; Pentetic Acid; Rats; Rats, Inbred F344; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Experimental; Hydralazine; Imidazoles; In Situ Hybridization; Losartan; Male; Membrane Transport Proteins; NADPH Dehydrogenase; NADPH Oxidases; Phosphoproteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxide Dismutase; Systole; Tetrazoles | 1997 |
Monocyte chemoattractant protein-1 expression in aortic tissues of hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Chemokine CCL2; Hydralazine; Hypertension; Infusions, Parenteral; Macrophages; Male; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Mechanical; Transcription, Genetic | 1997 |
Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Apoptosis; Arginine; Biotin; Cyclosporine; Deoxyuracil Nucleotides; DNA Fragmentation; Enzyme Inhibitors; Fibrosis; Hydralazine; Immunosuppressive Agents; Ischemia; Kidney; Losartan; Macrophages; Male; Nephritis, Interstitial; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Staining and Labeling | 1998 |
Mechanisms contributing to angiotensin II regulation of body weight.
Topics: Adipose Tissue; Angiotensin II; Animals; Blood Pressure; Body Temperature; Body Weight; Dose-Response Relationship, Drug; Drinking; Hydralazine; Leptin; Male; Organ Size; Proteins; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1998 |
Angiotensin II induces vascular smooth muscle cell replication independent of blood pressure.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Cell Division; Data Interpretation, Statistical; DNA Replication; Hydralazine; Hyperplasia; Hypertrophy; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley | 1998 |
Dissociation of blood pressure reduction from end-organ damage in TGR(mREN2)27 transgenic hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Carbazoles; Carvedilol; Heart Function Tests; Hydralazine; Hypertension; Isoquinolines; Losartan; Norepinephrine; Propanolamines; Quinapril; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Tetrahydroisoquinolines | 1998 |
Tissue-localized angiotensin II enhances cardiac and renal disorders in Tsukuba hypertensive mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Catecholamines; Humans; Hydralazine; Hypertension; Kidney Diseases; Lisinopril; Mice; Mice, Inbred C57BL; Mice, Transgenic; Renin | 1998 |
Blocking angiotensin II ameliorates proteinuria and glomerular lesions in progressive mesangioproliferative glomerulonephritis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Cilazapril; Collagen; Disease Models, Animal; Glomerulonephritis, Membranoproliferative; Hydralazine; Kidney Failure, Chronic; Male; Proteinuria; Rats; Rats, Wistar; Renal Circulation; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta | 1999 |
Angiotensin II AT1-receptor blockade inhibits monocyte activation and adherence in transgenic (mRen2)27 rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Cell Count; Blood Pressure; Cell Adhesion; Endothelium, Vascular; Female; Heart Rate; Hematocrit; Hydralazine; Hypertension; Losartan; Male; Monocytes; Nitroblue Tetrazolium; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System | 1999 |
Renin-angiotensin system stimulates cardiac and renal disorders in Tsukuba hypertensive mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Humans; Hydralazine; Hypertension; Kidney Diseases; Lisinopril; Mice; Mice, Inbred C57BL; Renin; Renin-Angiotensin System; Survival Rate | 1999 |
Prevention of renal damage by angiotensin II blockade, accompanied by increased renal hepatocyte growth factor in experimental hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Blotting, Northern; Cilazapril; Data Interpretation, Statistical; Hepatocyte Growth Factor; Hydralazine; Hypertension, Renal; Imidazoles; Kidney; Kidney Tubules; Male; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Time Factors | 1999 |
Hypertension and renal injury in experimental polycystic kidney disease.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Enalapril; Fibrosis; Hydralazine; Hypertension, Renal; Kidney Glomerulus; Male; Polycystic Kidney, Autosomal Dominant; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Vasoconstrictor Agents | 1999 |
Increased leukotriene A(4) hydrolase expression in the heart of angiotensin II-induced hypertensive rat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blotting, Northern; Blotting, Western; Epoxide Hydrolases; Fibroblasts; Hemodynamics; Hydralazine; Hypertension; Imidazoles; Immunohistochemistry; Leukocytes; Myocardium; Prodrugs; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles; Time Factors; Up-Regulation; Vasodilator Agents | 1999 |
Angiotensin II enhances integrin and alpha-actinin expression in adult rat cardiac fibroblasts.
Topics: Actinin; Age Factors; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antigens, CD; Antihypertensive Agents; Biphenyl Compounds; Cardiomegaly; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Collagen; Fibroblasts; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression; Heart Ventricles; Hydralazine; Imidazoles; Integrin alphaV; Integrin beta Chains; Integrin beta1; Integrin beta3; Integrins; Irbesartan; Laminin; Losartan; Myocardium; Phosphorylation; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Up-Regulation; Vitronectin | 2000 |
Blood pressure-independent effects in rats with human renin and angiotensinogen genes.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Diuresis; Glomerular Filtration Rate; Humans; Hydralazine; Hydrochlorothiazide; Ki-67 Antigen; Kidney; Male; Myocardium; Natriuresis; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Renal Circulation; Renin; Reserpine; Sodium; Transgenes | 2000 |
Heme oxygenase-1 is upregulated in the kidney of angiotensin II-induced hypertensive rats : possible role in renoprotection.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cell Line, Transformed; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glomerular Filtration Rate; Heart Rate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemin; Hydralazine; Hypertension; Immunohistochemistry; Kidney Tubules, Proximal; Losartan; Norepinephrine; Oxidative Stress; Proteinuria; Protoporphyrins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Heme oxygenase-1 is upregulated in the rat heart in response to chronic administration of angiotensin II.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cell Division; Gene Expression Regulation, Enzymologic; Heart; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemodynamics; Hydralazine; Infusions, Intravenous; Kinetics; Losartan; Male; Myocardium; Norepinephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic | 2000 |
Effect of bosentan on NF-kappaB, inflammation, and tissue factor in angiotensin II-induced end-organ damage.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Bosentan; Cardiomegaly; Fibronectins; Heart; Humans; Hydralazine; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Kidney; Macrophages; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Renin; Sulfonamides; Thromboplastin; Transcription Factor AP-1; Vascular Cell Adhesion Molecule-1 | 2000 |
Increased gene expression of components of the renin-angiotensin system in glomeruli of genetically hypertensive rats.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blotting, Northern; Fibronectins; Gene Expression; Glomerulosclerosis, Focal Segmental; Hydralazine; Hypertension, Renal; Kidney Glomerulus; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Ribonucleases; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2000 |
Angiotensin-converting enzyme inhibitor prevents age-related endothelial dysfunction.
Topics: Acetylcholine; Administration, Oral; Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Biological Factors; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Enalapril; Endothelium, Vascular; Heart Rate; Hydralazine; Hydrochlorothiazide; In Vitro Techniques; Male; Mesenteric Arteries; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Inbred WKY; Vasodilation | 2000 |
Testosterone increases blood pressure and cardiovascular and renal pathology in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Captopril; Collagen; Coronary Vessels; Hydralazine; Hypertension; Kidney Glomerulus; Male; Myocardium; Orchiectomy; Rats; Rats, Inbred SHR; Testosterone | 2000 |
Paradoxical regulation of short promoter human renin transgene by angiotensin ii.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Hydralazine; Infusion Pumps, Implantable; Kidney; Mice; Mice, Transgenic; Promoter Regions, Genetic; Renin; RNA, Messenger; Up-Regulation; Vasodilator Agents | 2001 |
Temporary treatment of prepubescent rats with angiotensin inhibitors suppresses the development of hypertensive nephrosclerosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Gene Expression; Genetic Predisposition to Disease; Hydralazine; Hypertension; Indans; Kidney; Male; Nephrosclerosis; Proteinuria; Rats; Rats, Inbred SHR; Renin; Stroke; Tetrazoles; Time Factors; Vasodilator Agents | 2001 |
Antihypertensive drugs induce structural remodeling of the penile vasculature.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Enalapril; Hydralazine; Male; Methoxamine; Penis; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins; Ventricular Remodeling | 2001 |
Persistent cardiovascular effects of chronic renin-angiotensin system inhibition following withdrawal in adult spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Vessels; Cardiomegaly; Cardiovascular System; Drug Administration Schedule; Heart Rate; Hydralazine; Hypertension; Kidney; Male; Motor Activity; Perindopril; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Vasodilator Agents | 2001 |
Effects of angiotensin-converting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing-induced congestive heart failure.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Fibrillation; Dogs; Electrophysiology; Enalapril; Endomyocardial Fibrosis; Heart Atria; Heart Failure; Hemodynamics; Hydralazine; Isosorbide Dinitrate; Mitogen-Activated Protein Kinases; Renin-Angiotensin System; Signal Transduction; Tachycardia, Ventricular | 2001 |
The renin-angiotensin and adrenergic nervous system in cardiac hypertrophy in fructose-fed rats.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Catecholamines; Diet; Fructose; Glucose Tolerance Test; Heart Rate; Hydralazine; Hyperinsulinism; Hypertrophy, Left Ventricular; Imidazoles; Insulin; Male; Myocardium; Olmesartan Medoxomil; Organ Size; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Renin-Angiotensin System; Sympathetic Nervous System; Tetrazoles | 2002 |
Predominant activation of endothelin-dependent cardiac hypertrophy by norepinephrine in rat left ventricle.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Aortic Valve Stenosis; Atrial Natriuretic Factor; Endothelin Receptor Antagonists; Endothelins; Female; Gene Expression; Hydralazine; Hypertrophy, Left Ventricular; Norepinephrine; Phenylpropionates; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A | 2002 |
Treatment of congestive heart failure.
Topics: Angioedema; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Heart Failure; Humans; Hydralazine; Nitrates; Vasodilator Agents | 2002 |
Angiotensin converting enzyme inhibition decreases cell turnover in the neonatal rat heart.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Antihypertensive Agents; Apoptosis; bcl-X Protein; Clusterin; Enalapril; Female; Glycoproteins; Heart; Hydralazine; In Situ Nick-End Labeling; Molecular Chaperones; Myocardium; Pregnancy; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Renin | 2002 |
Resistance artery mechanics and composition in angiotensin II-infused rats: effects of aldosterone antagonism.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Collagen; Hydralazine; Male; Mesenteric Arteries; Microscopy, Confocal; Mineralocorticoid Receptor Antagonists; Rats; Rats, Sprague-Dawley; Renin; Spironolactone; Vascular Resistance; Vasodilator Agents | 2003 |
NO and endogenous angiotensin II interact in the generation of renal sympathetic nerve activity in conscious rats.
Topics: Angiotensin II; Animals; Blood Pressure; Diet; Enzyme Inhibitors; Heart Rate; Hydralazine; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Sodium, Dietary; Sympathetic Nervous System; Vasodilator Agents | 2004 |
Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice.
Topics: Acetophenones; Angiotensin II; Animals; Blood Pressure; Body Weight; Collagen; Endothelium, Vascular; Enzyme Inhibitors; Hydralazine; Hypertension; Male; Mesenteric Arteries; Mice; Mice, Inbred BALB C; NADPH Oxidases; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 2004 |
Elevated arterial pressure impairs autoregulation independently of AT(1) receptor activation.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Drug Therapy, Combination; Homeostasis; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reserpine; Tetrazoles; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Heat shock treatment protects against angiotensin II-induced hypertension and inflammation in aorta.
Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Blotting, Western; Electrophoretic Mobility Shift Assay; Heat-Shock Response; Hot Temperature; HSP70 Heat-Shock Proteins; Hydralazine; Hypertension; Imidazoles; Inflammation; Interleukin-6; Intracellular Signaling Peptides and Proteins; Male; NF-kappa B; NF-kappa B p50 Subunit; Norepinephrine; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Thiophenes; Transcription Factor RelA | 2004 |
Temporary angiotensin II blockade at the prediabetic stage attenuates the development of renal injury in type 2 diabetic rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Collagen; Connective Tissue Growth Factor; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Hydralazine; Imidazoles; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Male; NADPH Oxidases; Olmesartan Medoxomil; Prediabetic State; Rats; Rats, Inbred OLETF; Receptors, Angiotensin; Renin; Tetrazoles; Thiazepines; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta | 2005 |
Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1-7) expression in the aorta of spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Aorta, Thoracic; Atenolol; Carboxypeptidases; Carotid Arteries; Gene Expression Regulation, Enzymologic; Hydralazine; Hypertension; Imidazoles; Male; Olmesartan Medoxomil; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; RNA, Messenger; Tetrazoles; Vasodilator Agents | 2005 |
Combined angiotensin II type 1 and type 2 receptor blockade on vascular remodeling and matrix metalloproteinases in resistance arteries.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blotting, Western; Collagen Type I; Elasticity; Elastin; Fibronectins; Hydralazine; Losartan; Male; Matrix Metalloproteinase 2; Mesenteric Artery, Superior; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vascular Resistance | 2005 |
Expression of endothelial nitric oxide synthase is suppressed in the renal vasculature of angiotensinogen-gene knockout mice.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Blotting, Western; Hydralazine; Hypotension; Immunoenzyme Techniques; Kidney; Mice; Mice, Inbred ICR; Mice, Knockout; NADPH Dehydrogenase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Sodium; Sodium Chloride, Dietary; Water-Electrolyte Balance | 2006 |
Role of angiotensin type-1 and angiotensin type-2 receptors in the expression of vascular integrins in angiotensin II-infused rats.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Vessels; Hydralazine; Hypertension; Infusion Pumps; Integrins; Losartan; Male; Osteopontin; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sialoglycoproteins; Vasoconstrictor Agents; Vasodilator Agents | 2006 |
Endothelial progenitor cell differentiation and senescence in an angiotensin II-infusion rat model.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Bone Marrow Cells; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cellular Senescence; Endothelium, Vascular; Hydralazine; Male; Rats; Rats, Wistar; Stem Cells; Telomerase; Tetrazoles; Valine; Valsartan; Vasodilator Agents | 2006 |
Expression and localization of PDGF-B, PDGF-D, and PDGF receptor in the kidney of angiotensin II-infused rat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Cell Proliferation; Gene Expression Regulation; Hydralazine; In Situ Hybridization; Iron; Kidney; Lipid Metabolism; Losartan; Lymphokines; Male; Norepinephrine; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Receptor, Platelet-Derived Growth Factor beta; RNA, Messenger; Vasoconstrictor Agents | 2006 |
Effects of angiotensin II on NO bioavailability evaluated using a catheter-type NO sensor.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Catheterization; Cyclic N-Oxides; Disease Models, Animal; Hydralazine; Male; Nitric Oxide; Oxidants; Oxidative Stress; Rabbits; Spin Labels; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents; Vasodilator Agents | 2006 |
Genetic disruption of guanylyl cyclase/natriuretic peptide receptor-A upregulates ACE and AT1 receptor gene expression and signaling: role in cardiac hypertrophy.
Topics: Angiotensin II; Animals; Captopril; Cardiomegaly; Cyclic GMP; Fibrosis; Gene Expression Regulation; Guanylate Cyclase; Heart Ventricles; Hydralazine; Hypertension; Interleukin-6; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptors, Atrial Natriuretic Factor; Renin-Angiotensin System; Signal Transduction; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha | 2007 |
Angiotensin inhibition decreases progression of advanced atherosclerosis and stabilizes established atherosclerotic plaques.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Blood Pressure; Body Weight; Disease Progression; Elasticity; Female; Hydralazine; Lipids; Losartan; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Vasoconstrictor Agents | 2007 |
Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine.
Topics: Acetophenones; Albuminuria; Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Cardiomegaly; Carotid Arteries; Cyclic N-Oxides; Hydralazine; Hypertension; Hypolipidemic Agents; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Simvastatin; Spin Labels; Superoxides; Tunica Media | 2007 |
Synergetic antioxidant and vasodilatory action of carbon monoxide in angiotensin II - induced cardiac hypertrophy.
Topics: Angiotensin II; Animals; Antioxidants; Aorta; Blood Pressure; Carbon Monoxide; Carboxyhemoglobin; Cardiomegaly; Hydralazine; Hypercholesterolemia; Lipid Peroxides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Receptors, LDL; Vasodilator Agents | 2007 |
Novel mechanism and role of angiotensin II induced vascular endothelial injury in hypertensive diastolic heart failure.
Topics: Acetophenones; Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Apoptosis; Biopterins; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Endothelium, Vascular; Heart Failure, Diastolic; Hydralazine; Hypertension; Male; MAP Kinase Kinase Kinase 5; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium Chloride, Dietary; Superoxides; Tetrazoles; Time Factors; Valine; Valsartan; Vasodilation | 2007 |
Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation.
Topics: Acetophenones; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Astrocytes; Blood Pressure; Cerebral Cortex; Enzyme Activation; Enzyme Inhibitors; Humans; Hydralazine; Hypertension; Inflammation; Male; NADPH Oxidases; Neurons; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Sodium Chloride; Stroke; Tetrazoles; Valine; Valsartan | 2008 |
ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Blood Pressure; Cholesterol, Dietary; Disease Models, Animal; Hydralazine; Hypercholesterolemia; Hypertension; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Norepinephrine; Receptors, LDL; Risk Factors; Time Factors | 2009 |
Protective effects of angiotensin AT1 receptor blockade in malignant hypertension in the rat.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atrasentan; Blood Pressure; Endothelin-1; Hydralazine; Hypertension, Malignant; Losartan; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renal Insufficiency | 2009 |
Role of angiotensin II in the remodeling induced by a chronic increase in flow in rat mesenteric resistance arteries.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Flow Velocity; Blotting, Western; Butadienes; Cyclic N-Oxides; Extracellular Signal-Regulated MAP Kinases; Hydralazine; Male; Mesenteric Arteries; Mice; Mice, Knockout; Microscopy, Confocal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Nitriles; Perindopril; Rats; Rats, Wistar; Reactive Oxygen Species; Spin Labels; Tetrazoles; Vascular Resistance; Vasodilator Agents | 2010 |
Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension.
Topics: Administration, Oral; Adoptive Transfer; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Genes, T-Cell Receptor alpha; Genes, T-Cell Receptor beta; Homeodomain Proteins; Hydralazine; Hypertension; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Norepinephrine; Receptors, Antigen, T-Cell, alpha-beta; Superoxides; T-Lymphocytes; Third Ventricle; Time Factors; Vasculitis | 2010 |
Salt-induced cardiac hypertrophy and interstitial fibrosis are due to a blood pressure-independent mechanism in Wistar rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Collagen Type I; Collagen Type III; Disease Models, Animal; Drinking; Eating; Echocardiography; Fibrosis; Gene Expression; Heart Ventricles; Hydralazine; Hypertension; Losartan; Male; Myocardium; Potassium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Sodium; Sodium Chloride, Dietary; Transforming Growth Factor beta; Urine | 2010 |
Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model.
Topics: Albuminuria; Anemia; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chronic Disease; Desoxycorticosterone; Disease Models, Animal; Disease Progression; Fibrosis; Genetic Predisposition to Disease; Glomerulonephritis; Heart Diseases; Hydralazine; Hypertension; Imidazoles; Infusion Pumps, Implantable; Infusions, Subcutaneous; Kidney; Kidney Diseases; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Nephrectomy; Sodium Chloride, Dietary; Species Specificity; Telemetry; Tetrazoles; Time Factors; X-Ray Microtomography | 2010 |
Antihypertensive therapy increases tetrahydrobiopterin levels and NO/cGMP signaling in small arteries of angiotensin II-infused hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biopterins; Cyclic GMP; GTP Cyclohydrolase; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Reserpine; Signal Transduction | 2011 |
Tetrahydrobiopterin and hypertension: more than an emigrating story.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biopterins; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Reserpine; Signal Transduction | 2011 |
Angiotensin-(1-7) blockade attenuates captopril- or hydralazine-induced cardiovascular protection in spontaneously hypertensive rats treated with NG-nitro-L-arginine methyl ester.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Brain; Captopril; Cytokines; Heart; Hydralazine; Hypertension; In Vitro Techniques; Insulin; Kidney; Leptin; Male; Myocardial Contraction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Peptide Fragments; Perfusion; Proteinuria; Rats; Rats, Inbred SHR; Ventricular Function, Left | 2011 |
Angiotensin II infusion-induced inflammation, monocytic fibroblast precursor infiltration, and cardiac fibrosis are pressure dependent.
Topics: Angiotensin II; Animals; Blood Pressure; Fibrosis; Hydralazine; Hypertrophy, Left Ventricular; Inflammation; Inflammation Mediators; Infusion Pumps; Leukocyte Common Antigens; Male; Mice; Mice, Inbred C57BL; Monocytes; Myofibroblasts; Random Allocation | 2011 |
Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats: the critical role of ASK1 and VEGF.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Biphenyl Compounds; Blood Pressure; Blotting, Western; Capillaries; Cells, Cultured; Cyclic N-Oxides; Endothelial Cells; Heart Diseases; Hydralazine; Hypertension; Hypertrophy, Left Ventricular; Immunohistochemistry; Irbesartan; MAP Kinase Kinase Kinase 5; Myocardial Ischemia; Oxidative Stress; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Spin Labels; Superoxides; Tetrazoles; Ultrasonography; Vascular Endothelial Growth Factor A | 2012 |
Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice.
Topics: Actins; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cellular Senescence; Eplerenone; Genes, p16; Genes, p53; Hydralazine; Hypertension; Imidazoles; Kidney; Mice; Mice, Inbred C57BL; p21-Activated Kinases; Sirtuin 1; Sodium Chloride; Spironolactone; Tetrazoles | 2012 |
Enhanced intrarenal receptor-mediated prorenin activation in chronic progressive anti-thymocyte serum nephritis rats on high salt intake.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antilymphocyte Serum; Blood Pressure; Hydralazine; Imidazoles; Kidney; Male; Nephritis; Prorenin Receptor; Rats; Rats, Wistar; Receptors, Cell Surface; Renin; Sodium Chloride, Dietary; T-Lymphocytes; Tetrazoles | 2012 |
Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterial Pressure; Biomarkers; Blood Vessels; Case-Control Studies; Cell Adhesion Molecules; Cell Line; Disease Models, Animal; Humans; Hydralazine; Hypertension; Hypertension, Renovascular; Losartan; Male; Morpholinos; Prehypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Cell Surface; RNA, Messenger; Time Factors; Up-Regulation; Vasodilator Agents | 2012 |
EP1 disruption attenuates end-organ damage in a mouse model of hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Female; Humans; Hydralazine; Hypertension; Kaplan-Meier Estimate; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; Receptors, Prostaglandin E, EP1 Subtype | 2012 |
Selective PDE5A inhibition with sildenafil rescues left ventricular dysfunction, inflammatory immune response and cardiac remodeling in angiotensin II-induced heart failure in vivo.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic Nucleotide Phosphodiesterases, Type 5; Cytokines; Extracellular Matrix; Heart Failure; Heart Function Tests; Hydralazine; Male; Mice; Mice, Inbred C57BL; Myocarditis; Myocardium; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Sildenafil Citrate; Sulfones; Vasoconstrictor Agents; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2012 |
Renin inhibition ameliorates renal damage through prominent suppression of both angiotensin I and II in human renin angiotensinogen transgenic mice with high salt loading.
Topics: Albuminuria; Amides; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Cytoprotection; Disease Models, Animal; Disease Progression; Down-Regulation; Fumarates; Humans; Hydralazine; Hypertension; Kidney; Kidney Diseases; Mice; Mice, Transgenic; Ramipril; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Time Factors | 2014 |
Aggravated renal tubular damage and interstitial fibrosis in mice lacking guanylyl cyclase-A (GC-A), a receptor for atrial and B-type natriuretic peptides.
Topics: Actins; Angiotensin II; Animals; Antigens, Differentiation; Antihypertensive Agents; Atrophy; Blood Pressure; Cadherins; Chemokine CCL2; Fibrosis; Gene Expression; Hydralazine; Intracellular Signaling Peptides and Proteins; Kidney Tubules; Male; Membrane Proteins; Mice; Mice, Knockout; Osteopontin; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Sodium Chloride; Vasoconstrictor Agents | 2015 |
High-salt intake induces cardiomyocyte hypertrophy in rats in response to local angiotensin II type 1 receptor activation.
Topics: Acetylcysteine; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Cardiomegaly; Heart Rate; Hematocrit; Hydralazine; Losartan; Male; Myocytes, Cardiac; Potassium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sodium; Sodium Chloride, Dietary; Thiobarbituric Acid Reactive Substances | 2014 |
Renin inhibition reduces atherosclerotic plaque neovessel formation and regresses advanced atherosclerotic plaques.
Topics: Amides; Angiotensin II; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Blood Pressure; Carrier Proteins; Cathepsins; Chemokine CCL2; Extracellular Matrix; Fumarates; Gene Silencing; Human Umbilical Vein Endothelial Cells; Humans; Hydralazine; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Nuclear Proteins; Plaque, Atherosclerotic; Receptor, Angiotensin, Type 1; Renin; Toll-Like Receptor 2; Treatment Outcome; Vascular Cell Adhesion Molecule-1 | 2014 |
Augmented circadian rhythm of the intrarenal renin-angiotensin systems in anti-thymocyte serum nephritis rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Antilymphocyte Serum; Circadian Rhythm; Disease Models, Animal; Hydralazine; Kidney; Lymphocytes; Male; Nephritis; Olmesartan Medoxomil; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2016 |
Activation of the Renin-Angiotensin System Promotes Colitis Development.
Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Colitis; Colon; Epithelial Cells; Fumarates; Humans; Hydralazine; Inflammatory Bowel Diseases; Losartan; Mice; Mice, Transgenic; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Th17 Cells | 2016 |
Modulation of renal oxygenation and perfusion in rat kidney monitored by quantitative diffusion and blood oxygen level dependent magnetic resonance imaging on a clinical 1.5T platform.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Diffusion; Diffusion Magnetic Resonance Imaging; Diuretics; Female; Furosemide; Hydralazine; Kidney; Magnetic Resonance Imaging; Oxygen; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Vasoconstrictor Agents | 2016 |
ACE (Angiotensin-Converting Enzyme) Inhibition Reverses Vasoconstriction and Impaired Dilation of Pial Collaterals in Chronic Hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Captopril; Chronic Disease; Collateral Circulation; Hydralazine; Hypertension; Male; Pia Mater; Random Allocation; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; rho-Associated Kinases; Tetrazoles; Vasoconstriction; Vasodilator Agents; Vasomotor System | 2020 |
Angiotensin II type 1a receptor loss ameliorates chronic tubulointerstitial damage after renal ischemia reperfusion.
Topics: Angiotensin II; Animals; Blood Pressure; Hydralazine; Ischemia; Kidney; Male; Mice; Mice, Knockout; Receptor, Angiotensin, Type 1; Renal Insufficiency, Chronic; Reperfusion | 2021 |