hydralazine and amrinone

hydralazine has been researched along with amrinone in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19909 (47.37)18.7374
1990's1 (5.26)18.2507
2000's5 (26.32)29.6817
2010's4 (21.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aldana, I; Alvarez, T; Bermejillo, MJ; Fernandez-Alvarez, E; Font, M; Latre, JA; Lopez-Unzu, MJ; Monge, A; Santiago, E1
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Campos-Toimil, M; Cuiñas, A; Munín, J; Quezada, E; Santana, L; Uriarte, E; Viña, D1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ruggie, N1
van Meel, JC1
Alderman, MH; Marantz, PR; Tobin, JN1
Andrews, V; Fishman, AP; Janicki, JS; Kinasewitz, GT; Weber, KT1
Fowler, NO; Gabel, M; Millard, RW1
Medina, N; Packer, M; Yushak, M1
Larbig, D; Nasse, H1
Ganz, R; Levy, PS; Rich, S1
Efstathakis, D; Feinberg, H; Forman, R; Keung, E; LeJemtel, TH; Siegel, LA; Siskind, SJ; Sonnenblick, EH; Strom, J1

Reviews

4 review(s) available for hydralazine and amrinone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Congestive heart failure.
    The Medical clinics of North America, 1986, Volume: 70, Issue:4

    Topics: Aminopyridines; Amrinone; Angiotensin-Converting Enzyme Inhibitors; Cardiac Glycosides; Cardiotonic Agents; Diuretics; Dobutamine; Dopamine; Heart Failure; Humans; Hydralazine; Milrinone; Nitrates; Nitroprusside; Prazosin; Pyridones; Sympathomimetics; Vasodilator Agents

1986
Diagnostic heterogeneity in clinical trials for congestive heart failure.
    Annals of internal medicine, 1988, Jul-01, Volume: 109, Issue:1

    Topics: Amrinone; Clinical Trials as Topic; Digoxin; Heart Failure; Humans; Hydralazine; Metoprolol; Research Design

1988
Vasodilator and inotropic agents in treatment of chronic cardiac failure: clinical experience and response in exercise performance.
    American heart journal, 1981, Volume: 102, Issue:3 Pt 2

    Topics: Aerobiosis; Aminopyridines; Amrinone; Anaerobiosis; Cardiotonic Agents; Heart Failure; Hemodynamics; Humans; Hydralazine; Neurotransmitter Agents; Physical Exertion; Piperazines; Quinazolines; Sympathetic Nervous System; Vasodilator Agents

1981

Other Studies

15 other study(ies) available for hydralazine and amrinone

ArticleYear
New 5H-pyridazino[4,5-b]indole derivatives. Synthesis and studies as inhibitors of blood platelet aggregation and inotropics.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:10

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cardiotonic Agents; Dinoprostone; Female; Guinea Pigs; Humans; Indoles; Platelet Aggregation Inhibitors; Pyridazines; Thromboxane A2; Thromboxane-A Synthase

1991
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Synthesis, biological evaluation and structure-activity relationships of new phthalazinedione derivatives with vasorelaxant activity.
    European journal of medicinal chemistry, 2014, Jul-23, Volume: 82

    Topics: Animals; Aorta, Thoracic; Cell Line; Dose-Response Relationship, Drug; Male; Molecular Structure; Muscle, Smooth; Phthalazines; Rats; Rats, Inbred WKY; Rats, Wistar; Structure-Activity Relationship; Vasodilator Agents

2014
Comparison of some new positive inotropic agents in guinea pigs.
    Pharmacology, 1985, Volume: 31, Issue:1

    Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiotonic Agents; Dose-Response Relationship, Drug; Enoximone; Guinea Pigs; Heart Rate; Hydralazine; Imidazoles; Isoproterenol; Male; Myocardial Contraction; Ouabain; Vasodilation

1985
Hemodynamic and regional blood flow distribution responses to dextran, hydralazine, isoproterenol and amrinone during experimental cardiac tamponade.
    Journal of the American College of Cardiology, 1983, Volume: 1, Issue:6

    Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Blood Volume; Cardiac Output; Cardiac Tamponade; Cardiotonic Agents; Dextrans; Dogs; Female; Heart Rate; Hemodynamics; Hydralazine; Isoproterenol; Male; Microspheres; Radioisotopes; Regional Blood Flow; Stroke Volume; Vascular Resistance

1983
Correction of dilutional hyponatremia in severe chronic heart failure by converting-enzyme inhibition.
    Annals of internal medicine, 1984, Volume: 100, Issue:6

    Topics: Adult; Aged; Aminopyridines; Amrinone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiotonic Agents; Female; Heart Failure; Hemodynamics; Humans; Hydralazine; Hyponatremia; Male; Middle Aged; Prazosin; Proline

1984
[Alternatives to digitalis therapy].
    Deutsche medizinische Wochenschrift (1946), 1983, Nov-11, Volume: 108, Issue:45

    Topics: Aminopyridines; Amrinone; Captopril; Catecholamines; Diuretics; Heart Failure; Humans; Hydralazine; Nitrates; Nitroprusside; Practolol; Prazosin; Prenalterol; Vasodilator Agents

1983
Comparative actions of hydralazine, nifedipine and amrinone in primary pulmonary hypertension.
    The American journal of cardiology, 1983, Nov-01, Volume: 52, Issue:8

    Topics: Adult; Aminopyridines; Amrinone; Cardiac Catheterization; Cardiac Output; Female; Humans; Hydralazine; Hypertension, Pulmonary; Male; Middle Aged; Nifedipine; Pulmonary Wedge Pressure; Stroke Volume; Vascular Resistance; Vasodilator Agents

1983
Beneficial effects of amrinone-hydralazine combination on resting hemodynamics and exercise capacity in patients with severe congestive heart failure.
    Circulation, 1981, Volume: 63, Issue:4

    Topics: Adult; Aged; Aminopyridines; Amrinone; Blood Pressure; Cardiac Output; Cardiotonic Agents; Drug Therapy, Combination; Exercise Test; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Hydralazine; Male; Middle Aged; Pulmonary Wedge Pressure; Rest; Vascular Resistance

1981