hydralazine and amiloride

hydralazine has been researched along with amiloride in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's5 (41.67)18.2507
2000's2 (16.67)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Newell, K; Stratford, I; Tannock, I; Wood, P1
Diakos, A; Kontoyannis, DA; Kontoyannis, SA; Moulopoulos, SD; Sideris, DA1
Löllgen, H; Schmidt, A; Upmeyer, HJ1
Hasuda, K; Lee, C; Tannock, IF1
Luo, J; Tannock, IF1
Tannock, IF; Yamagata, M1
Iwai, N; Nishimura, M; Ohtsuka, K; Takahashi, H; Yoshimura, M1

Reviews

1 review(s) available for hydralazine and amiloride

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for hydralazine and amiloride

ArticleYear
[Double-blind comparison of fixed combination preparations of a beta blocker and a diuretic and beta blocker, a diuretic and hydralazine in patients with coronary heart disease and arterial hypertension].
    Medizinische Klinik (Munich, Germany : 1983), 1986, Nov-11, Volume: 81, Issue:23

    Topics: Adrenergic beta-Antagonists; Aged; Amiloride; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation

1986

Other Studies

10 other study(ies) available for hydralazine and amiloride

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Effects of agents which inhibit the regulation of intracellular pH on murine solid tumours.
    British journal of cancer, 1992, Volume: 66, Issue:2

    Topics: Amiloride; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Division; Cell Survival; Fibrosarcoma; Homeostasis; Hydralazine; Hydrogen-Ion Concentration; Kinetics; Mice; Nigericin; Sarcoma, Experimental; Tumor Cells, Cultured

1992
Antihypertensive treatment for the management of premature ventricular complexes. Pilot study.
    Acta cardiologica, 1988, Volume: 43, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Blood Pressure; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardiography; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Infusions, Intravenous; Male; Metaraminol; Methyldopa; Middle Aged; Nitroprusside

1988
Antitumor activity of nigericin and 5-(N-ethyl-N-isopropyl)amiloride: an approach to therapy based on cellular acidification and the inhibition of regulation of intracellular pH.
    Oncology research, 1994, Volume: 6, Issue:6

    Topics: Amiloride; Animals; Cell Hypoxia; Cell Survival; Combined Modality Therapy; Drug Screening Assays, Antitumor; Drug Synergism; Female; Fibrosarcoma; Glucose; Hydralazine; Hydrogen-Ion Concentration; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Transplantation; Nigericin; Organoids; Protons; Sarcoma, Experimental

1994
Inhibition of the regulation of intracellular pH: potential of 5-(N,N-hexamethylene) amiloride in tumour-selective therapy.
    British journal of cancer, 1994, Volume: 70, Issue:4

    Topics: Amiloride; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cell Death; Combined Modality Therapy; Disease Models, Animal; Flow Cytometry; Hydralazine; Hydrogen-Ion Concentration; Intracellular Fluid; Kinetics; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Nigericin; Sarcoma, Experimental; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured

1994
The chronic administration of drugs that inhibit the regulation of intracellular pH: in vitro and anti-tumour effects.
    British journal of cancer, 1996, Volume: 73, Issue:11

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Antineoplastic Agents; Antiporters; Bicarbonates; Cell Line; Cell Survival; Chloride-Bicarbonate Antiporters; Chlorides; Female; Fibrosarcoma; Hydralazine; Hydrogen-Ion Concentration; Kinetics; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Nigericin; Sarcoma, Experimental; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured

1996
Regulation of brain renin-angiotensin system by benzamil-blockable sodium channels.
    The American journal of physiology, 1999, Volume: 276, Issue:5

    Topics: Amiloride; Animals; Arginine Vasopressin; Blood Pressure; Brain; Brain Chemistry; Desoxycorticosterone; DNA Primers; Gene Expression Regulation, Enzymologic; Heart Rate; Hydralazine; Hypertension, Renal; Injections, Intraventricular; Male; Norepinephrine; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Rats; Rats, Wistar; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Sodium Channels; Sodium Chloride; Vasodilator Agents

1999