hydralazine and acebutolol

hydralazine has been researched along with acebutolol in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's1 (10.00)18.2507
2000's5 (50.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dubos, JP; Gremillet, C; Kacet, N; Lequien, P; Morisot, C; Remy-Jardin, M1
Hidaka, H; Sawada, S; Tanioka, Y; Yasuda, Y1
Corvol, P; Lardoux, MD; Thibonnier, M1

Reviews

1 review(s) available for hydralazine and acebutolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for hydralazine and acebutolol

ArticleYear
Comparative trial of labetalol and acebutolol, alone or associated with dihydralazine, in treatment of essential hypertension.
    British journal of clinical pharmacology, 1980, Volume: 9, Issue:6

    Topics: Acebutolol; Adult; Clinical Trials as Topic; Dihydralazine; Drug Therapy, Combination; Ethanolamines; Female; Humans; Hydralazine; Hypertension; Labetalol; Male; Middle Aged; Renin

1980

Other Studies

8 other study(ies) available for hydralazine and acebutolol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neonatal hypertension and thrombosis of the ductus arteriosus.
    American journal of perinatology, 1991, Volume: 8, Issue:2

    Topics: Acebutolol; Captopril; Child, Preschool; Ductus Arteriosus; Female; Follow-Up Studies; Humans; Hydralazine; Infant, Newborn; Persistent Fetal Circulation Syndrome; Radiography; Renal Artery; Renal Artery Obstruction; Thrombosis

1991
The effects of acebutolol alone and in combination with furosemide or hydralazine in experimentally induced hypertensive G-minipigs.
    Jikken dobutsu. Experimental animals, 1986, Volume: 35, Issue:4

    Topics: Acebutolol; Aldosterone; Animals; Drug Therapy, Combination; Female; Furosemide; Heart Rate; Hydralazine; Hypertension; Renin; Swine; Swine, Miniature

1986