hycanthone and praziquantel

hycanthone has been researched along with praziquantel in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199012 (63.16)18.7374
1990's1 (5.26)18.2507
2000's0 (0.00)29.6817
2010's4 (21.05)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Bruce, JI; Tsao, GC; Wong, LJ; Wong, SS1
Hilderson, H; Rollinson, D; Southgate, VR; Vercruysse, J1
Doenhoff, MJ; Fletcher, C; Sabah, AA; Webbe, G2
Brindley, PJ; Sher, A1
Archer, S1
De Cock, KM1
de Jesus Pedro, R; de Souza Dias, LC; Deberaldini, ER1
Gilles, HM1
Kim, RA; Lukacs, J; MacInnis, AJ; Tanaka, RD2
McMahon, JE1
Bain, J; Bickle, Q; Doenhoff, M; Nelson, G; Webbe, G1
Cao, X; Guzman, M; LoVerde, PT; McHardy, SF; Rugel, A; Tarpley, RS; Taylor, AB1

Reviews

2 review(s) available for hycanthone and praziquantel

ArticleYear
The chemotherapy of schistosomiasis.
    Annual review of pharmacology and toxicology, 1985, Volume: 25

    Topics: Animals; Chemical Phenomena; Chemistry; Diphenylamine; Humans; Hycanthone; Isothiocyanates; Niridazole; Oxamniquine; Praziquantel; Pyrazines; Schistosomiasis; Schistosomicides; Thiocyanates; Thiones; Thiophenes; Trichlorfon

1985
Human schistosomiasis and its management.
    The Journal of infection, 1984, Volume: 8, Issue:1

    Topics: Animals; Humans; Hycanthone; Oxamniquine; Praziquantel; Schistosoma; Schistosomiasis; Trichlorfon

1984

Other Studies

17 other study(ies) available for hycanthone and praziquantel

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Inhibition of in vitro RNA synthesis by hycanthone, oxamniquine and praziquantel.
    Experientia, 1990, May-15, Volume: 46, Issue:5

    Topics: Animals; Cell Nucleus; Cricetinae; Depression, Chemical; DNA; Hycanthone; Liver; Nitroquinolines; Oxamniquine; Praziquantel; RNA; Thioxanthenes

1990
Experimental chemotherapy of Schistosoma curassoni in mice.
    Parasitology research, 1989, Volume: 75, Issue:7

    Topics: Animals; Disease Models, Animal; Female; Hycanthone; Male; Mice; Nitroquinolines; Oxamniquine; Praziquantel; Schistosomiasis; Thioxanthenes; Trichlorfon

1989
Schistosoma mansoni: chemotherapy of infections of different ages.
    Experimental parasitology, 1986, Volume: 61, Issue:3

    Topics: Animals; Antimony Potassium Tartrate; Diphenylamine; Female; Hycanthone; Isothiocyanates; Mice; Mice, Inbred CBA; Niridazole; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Thiocyanates; Time Factors

1986
Anti-schistosomal drugs: observations on the mechanism of drug resistance to hycanthone, and on the involvement of host antibodies in the mode of action of praziquantel.
    Memorias do Instituto Oswaldo Cruz, 1987, Volume: 82 Suppl 4

    Topics: Animals; Antibodies, Helminth; Antibody-Dependent Cell Cytotoxicity; Drug Resistance; Hycanthone; Mice; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Thioxanthenes

1987
Schistosoma mansoni: reduced efficacy of chemotherapy in infected T-cell-deprived mice.
    Experimental parasitology, 1985, Volume: 60, Issue:3

    Topics: Animals; Antilymphocyte Serum; Diphenylamine; Hycanthone; Isothiocyanates; Mice; Mice, Inbred CBA; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; T-Lymphocytes; Thiocyanates; Thymectomy

1985
Use of praziquantel in patients with schistosomiasis mansoni previously treated with oxamniquine and/or hycanthone: resistance of Schistosoma mansoni to schistosomicidal agents.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1982, Volume: 76, Issue:5

    Topics: Adolescent; Adult; Animals; Child; Drug Resistance; Female; Humans; Hycanthone; Isoquinolines; Mice; Nitroquinolines; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis; Thioxanthenes

1982
The treatment of schistosomiasis.
    The Journal of antimicrobial chemotherapy, 1981, Volume: 7, Issue:2

    Topics: Humans; Hycanthone; Niridazole; Oxamniquine; Praziquantel; Schistosomiasis; Trichlorfon

1981
Effects of hycanthone and praziquantel on monoamine oxidase and cholinesterases in Schistosoma mansoni.
    The Journal of parasitology, 1981, Volume: 67, Issue:1

    Topics: Animals; Brain; Cholinesterases; Dose-Response Relationship, Drug; Hycanthone; Isoquinolines; Liver; Mice; Monoamine Oxidase; Praziquantel; Schistosoma mansoni; Thioxanthenes

1981
A note on drug trials in schistosomiasis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1981, Volume: 75, Issue:4

    Topics: Drug Evaluation; Humans; Hycanthone; Isoquinolines; Praziquantel; Schistosoma haematobium; Schistosomiasis; Seasons; Tanzania

1981
Factors affecting the acquisition of resistance against Schistosoma mansoni in the mouse. V. Reduction in the degree of resistance to reinfection after chemotherapeutic elimination of recently patent primary infections.
    Journal of helminthology, 1980, Volume: 54, Issue:1

    Topics: Animals; Antimony Potassium Tartrate; Hycanthone; Immunity, Active; Mice; Mice, Inbred CBA; Niridazole; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis; Schistosomicides

1980
Development of a cell-free protein-synthesizing system from Schistosoma mansoni and a comparison of the effects of hycanthone and praziquantel on this system.
    The Journal of parasitology, 1980, Volume: 66, Issue:3

    Topics: Animals; Cell-Free System; Hycanthone; Isoquinolines; Kinetics; Polyribosomes; Praziquantel; Protein Biosynthesis; RNA, Transfer; Schistosoma mansoni; Thioxanthenes

1980
Molecular basis for hycanthone drug action in schistosome parasites.
    Molecular and biochemical parasitology, 2020, Volume: 236

    Topics: Animals; Crystallization; Crystallography, X-Ray; Drug Design; Drug Resistance; Humans; Hycanthone; Oxamniquine; Praziquantel; Protein Binding; Recombinant Proteins; Schistosoma haematobium; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Sulfotransferases

2020