Compounds > hycanthone

hycanthone and amsacrine

hycanthone has been researched along with amsacrine in 4 studies

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (25.00)	18.7374
1990's	1 (25.00)	18.2507
2000's	1 (25.00)	29.6817
2010's	1 (25.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Denny, WA; Feigon, J; Kearns, DR; Leupin, W	1
Aldous, S; Corbett, TH; Coughlin, SA; Huang, JI; Jones, JL; Klingbeil, KM; Mattes, KC; Perni, RB; Peverly, AD; Powles, RG; Rake, JB; Robinson, RG; Wentland, MP	1
Flanagan, JU; Kemp, CA; Maréchal, JD; Paine, MJ; Roberts, GC; Sutcliffe, MJ; van Eldik, AJ; Wolf, CR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1

Other Studies

4 other study(ies) available for hycanthone and amsacrine

Article	Year
Interactions of antitumor drugs with natural DNA: 1H NMR study of binding mode and kinetics. Journal of medicinal chemistry, 1984, Volume: 27, Issue:4 Topics: Antineoplastic Agents; Base Composition; Chemical Phenomena; Chemistry; DNA; Hydrogen Bonding; Intercalating Agents; Kinetics; Magnetic Resonance Spectroscopy; Structure-Activity Relationship	1984
Synthesis and antitumor activity of 4-aminomethylthioxanthenone and 5-aminomethylbenzothiopyranoindazole derivatives. Journal of medicinal chemistry, 1998, Sep-10, Volume: 41, Issue:19 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; DNA, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Indazoles; Intercalating Agents; Leukemia P388; Mice; Neoplasm Transplantation; Pancreatic Neoplasms; Pyrans; Structure-Activity Relationship; Thioxanthenes; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1998
Validation of model of cytochrome P450 2D6: an in silico tool for predicting metabolism and inhibition. Journal of medicinal chemistry, 2004, Oct-21, Volume: 47, Issue:22 Topics: Binding Sites; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Databases, Factual; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship	2004
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012