hx 600 has been researched along with alitretinoin in 2 studies
| Studies (hx 600) | Trials (hx 600) | Recent Studies (post-2010) (hx 600) | Studies (alitretinoin) | Trials (alitretinoin) | Recent Studies (post-2010) (alitretinoin) |
|---|---|---|---|---|---|
| 10 | 0 | 3 | 854 | 47 | 269 |
| Protein | Taxonomy | hx 600 (IC50) | alitretinoin (IC50) |
|---|---|---|---|
| retinoic acid receptor alpha isoform 1 | Homo sapiens (human) | 0.0084 | |
| retinoic acid receptor RXR-alpha isoform a | Homo sapiens (human) | 0.0189 | |
| Retinoic acid receptor alpha | Homo sapiens (human) | 0.007 | |
| Retinoic acid receptor beta | Homo sapiens (human) | 0.007 | |
| Retinoic acid receptor alpha | Mus musculus (house mouse) | 0.031 | |
| Retinoic acid receptor gamma | Homo sapiens (human) | 0.017 | |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | 0.0305 | |
| Retinoic acid receptor RXR-alpha | Mus musculus (house mouse) | 0.082 | |
| Retinoic acid receptor RXR-beta | Homo sapiens (human) | 0.012 | |
| Retinoic acid receptor RXR-gamma | Homo sapiens (human) | 0.004 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ebisawa, M; Eisenmann, G; Eyrolles, L; Fukasawa, H; Gronemeyer, H; Hashimoto, Y; Kagechika, H; Kawachi, E; Shudo, K; Umemiya, H | 1 |
| Ishizawa, M; Kagechika, H; Makishima, M | 1 |
2 other study(ies) available for hx 600 and alitretinoin
| Article | Year |
|---|---|
Regulation of retinoidal actions by diazepinylbenzoic acids. Retinoid synergists which activate the RXR-RAR heterodimers.
Topics: Azepines; Benzoates; Binding, Competitive; Cell Differentiation; Dibenzazepines; Dimerization; Drug Synergism; HL-60 Cells; Humans; Molecular Structure; Protein Binding; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Transcription Factors | 1997 |
NR4A nuclear receptors mediate carnitine palmitoyltransferase 1A gene expression by the rexinoid HX600.
Topics: Alitretinoin; Animals; Carnitine O-Palmitoyltransferase; Cell Line, Tumor; Dibenzazepines; Gene Expression; HEK293 Cells; Humans; Mice; Nuclear Receptor Subfamily 4, Group A, Member 1; Nuclear Receptor Subfamily 4, Group A, Member 2; Protein Multimerization; Rats; Retinoid X Receptors; Tretinoin | 2012 |