hwa 138 has been researched along with pentoxifylline in 22 studies
| Studies (hwa 138) | Trials (hwa 138) | Recent Studies (post-2010) (hwa 138) | Studies (pentoxifylline) | Trials (pentoxifylline) | Recent Studies (post-2010) (pentoxifylline) |
|---|---|---|---|---|---|
| 22 | 0 | 0 | 4,437 | 657 | 943 |
| Protein | Taxonomy | hwa 138 (IC50) | pentoxifylline (IC50) |
|---|---|---|---|
| Acetylcholinesterase | Homo sapiens (human) | 6.6 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.09) | 18.7374 |
| 1990's | 20 (90.91) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bahrami, S; Buurman, WA; Redl, H; Schlag, G | 1 |
| Gunning, K; Masouyé, P; Morel, DR; Pittet, JF; Suter, PM | 1 |
| Schmid-Schönbein, GW; Wong, PM | 1 |
| Hawkins, EP; Kaplan, SL; Mason, EO; Rodriguez, AF | 1 |
| Keyhani, A; Lopez-Berestein, G; Luke, DR; McQueen, TJ; Mehta, R; Vadiei, K; Wasan, KM; White, RA | 1 |
| Berens, KL; Langston, JD; Luke, DR; Wasan, KM | 1 |
| Berens, KL; Luke, DR; Verani, RR | 1 |
| Lopez-Berestein, G; Luke, DR; McQueen, TJ; Wasan, KM | 1 |
| Schade, UF | 1 |
| Fujishima, S; Hatherill, JR; Hoffmann, H; Ishizaka, A; Raffin, TA; Yonemaru, M; Zheng, H | 1 |
| Hand, DL; Hand, WL | 1 |
| Duncker, HP; Koch, T; Möschet, B; Neuhof, H; Schönharting, M; Stein, A; van Ackern, K | 1 |
| Bunk, A; Dapper, F; Hata, H; Hehrlein, FW; Neuhof, H | 1 |
| Bahrami, S; Redl, H; Schlag, G; Yu, YH | 1 |
| Lagarde, M; Meskini, N; Némoz, G; Okyayuz-Baklouti, I; Prigent, AF | 1 |
| Alléra, A; Eisenhut, T; Endres, S; Gebert, U; Moeller, J; Schönharting, MM; Semmler, J | 1 |
| Birg, A; Frank, G; Hoffmann, H; Jochum, M; Schönharting, MM; Weis, M | 1 |
| Bauer, M; Herzog, C; Maier, M; Marzi, I | 1 |
| Bahrami, S; Leichtfried, G; Redl, H; Schlag, G; Shiga, H; Yao, YM | 1 |
| Bengtsson, A; Högåsen, K; Mollnes, TE; Redl, H; Schlag, G | 1 |
| Bendtzen, K; Jakobsen, PH; Koch, C | 1 |
| Kelleher, DK; Thews, O; Vaupel, P | 1 |
22 other study(ies) available for hwa 138 and pentoxifylline
| Article | Year |
|---|---|
Influence of the xanthine derivate HWA 138 on endotoxin-related coagulation disturbances: effects in non-sensitized vs D-galactosamine sensitized rats.
Topics: Animals; Antithrombin III; Blood Coagulation Disorders; Blood Glucose; Fibrinogen; Galactosamine; Hematologic Tests; Immunization; In Vitro Techniques; Leukocyte Count; Lipopolysaccharides; Male; Partial Thromboplastin Time; Pentoxifylline; Platelet Count; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1992 |
Xanthine derivative HWA 138 attenuates hemodynamic and oxygen uptake dysfunction secondary to severe endotoxin shock in sheep.
Topics: Animals; Disease Models, Animal; Endotoxins; Escherichia coli; Female; Half-Life; Hemodynamics; Male; Oxygen Consumption; Pentoxifylline; Sheep; Shock, Septic | 1992 |
Attenuation of spontaneous pseudopod formation in human neutrophils by pentoxifylline.
Topics: Actins; Adult; Complement C5a; Cytoplasm; Dose-Response Relationship, Drug; Endotoxins; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Pseudopodia; Receptors, Purinergic; Theophylline; Time Factors | 1991 |
Effect of dexamethasone or HWA-138 in combination with antibiotics in experimental Haemophilus influenzae type b infection.
Topics: Ampicillin; Animals; Animals, Newborn; Anti-Bacterial Agents; Bronchodilator Agents; Cefotaxime; Cefuroxime; Child; Dexamethasone; Drug Therapy, Combination; Ear, Inner; Haemophilus Infections; Haemophilus influenzae; Humans; Pentoxifylline; Rats; Rats, Inbred Strains | 1991 |
Antifungal activity of HWA-138 and amphotericin B in experimental systemic candidiasis.
Topics: Amphotericin B; Animals; Antifungal Agents; Candidiasis; Drug Synergism; Mice; Mice, Inbred ICR; Pentoxifylline | 1991 |
Influence of pentoxifylline and related analogues in endotoxemic renal failure.
Topics: Acute Kidney Injury; Animals; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Kidney; Male; Pentoxifylline; Rats; Rats, Inbred Strains | 1991 |
Benefit of vascular decongestion in glycerol-induced acute renal failure.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Blood Vessels; Dose-Response Relationship, Drug; Glycerol; Kidney; Kidney Tubular Necrosis, Acute; Male; Pentoxifylline; Random Allocation; Rats; Rats, Inbred Strains | 1991 |
Enhancement of the treatment of experimental candidiasis with vascular decongestants.
Topics: Amphotericin B; Animals; Candidiasis; Drug Therapy, Combination; Glomerular Filtration Rate; Kidney; Male; Pentoxifylline; Random Allocation; Rats; Rats, Inbred Strains; Renal Circulation; Theobromine; Vasoconstrictor Agents | 1990 |
The role of prostacyclin in the protective effects of pentoxifylline and other xanthine derivatives in endotoxin action in mice.
Topics: Animals; Endotoxins; Epoprostenol; Female; Indomethacin; Leukopenia; Lipopolysaccharides; Mice; Pentoxifylline; Theobromine; Tumor Necrosis Factor-alpha | 1989 |
Attenuation of acute lung injury in septic guinea-pigs by a new xanthine derivative (HWA-138).
Topics: Acute Disease; Animals; Blood Pressure; Bronchodilator Agents; Erythrocytes; Escherichia coli Infections; Guinea Pigs; Injections, Intravenous; Iodine Radioisotopes; Leukocyte Count; Lung Diseases; Pentoxifylline; Respiratory Tract Infections; Theobromine | 1989 |
Influence of pentoxifylline and its derivatives on antibiotic uptake and superoxide generation by human phagocytic cells.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Cells, Cultured; Clindamycin; Drug Interactions; Erythromycin; Humans; Macrolides; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Phagocytosis; Respiratory Burst; Roxithromycin; Superoxides | 1995 |
Influence of a pentoxifylline-analogue on the granulocyte-mediated pulmonary mediator release and vascular reaction.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Female; Histamine Release; Lung; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Pulmonary Artery; Rabbits; Tetradecanoylphorbol Acetate; Thromboxane B2; Vascular Resistance | 1993 |
Experimental studies of the influence of priming solutions on the systemic activation of complement during cardiopulmonary bypass: comparison between the use of albumin, hydroxyethyl starch and HWA-138.
Topics: Albumins; Cardiopulmonary Bypass; Complement Activation; Complement C3a; Drug Evaluation, Preclinical; Female; Heart-Lung Machine; Humans; Hydroxyethyl Starch Derivatives; Intraoperative Period; Isotonic Solutions; Male; Multivariate Analysis; Pentoxifylline; Ringer's Solution; Time Factors | 1993 |
Acute lung injury by endotoxin-induced mediators: prevention by HWA 138, a new xanthine derivative.
Topics: Animals; Cyclic AMP; Female; Humans; Lipopolysaccharides; Lung; Male; Neutrophils; Pentoxifylline; Rabbits; Sepsis | 1995 |
Phosphodiesterase inhibitory profile of some related xanthine derivatives pharmacologically active on the peripheral microcirculation.
Topics: Animals; Heart Ventricles; Isoenzymes; Male; Microcirculation; Pentoxifylline; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats; Rats, Sprague-Dawley; Xanthines | 1994 |
Xanthine derivatives: comparison between suppression of tumour necrosis factor-alpha production and inhibition of cAMP phosphodiesterase activity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Pentoxifylline; Theophylline; Tumor Necrosis Factor-alpha; Xanthines | 1993 |
Amelioration of endotoxin-induced acute lung injury in pigs by HWA 138 and A 80 2715: new analogs of pentoxifylline.
Topics: Animals; Bronchodilator Agents; Hemodynamics; Infusions, Intravenous; Leukocyte Count; Leukopenia; Lipopolysaccharides; Pentoxifylline; Pulmonary Circulation; Respiratory Distress Syndrome; Shock, Septic; Swine; Swine, Miniature; Xanthines | 1995 |
Influence of pentoxifylline and albifylline on liver microcirculation and leukocyte adhesion after hemorrhagic shock in the rat.
Topics: Animals; Cell Adhesion Molecules; Disease Models, Animal; Female; Liver Circulation; Pentoxifylline; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Single-Blind Method; Vasodilator Agents | 1996 |
Comparison of the efficacy of pentoxifylline and albifyllin (HWA 138) on endotoxin-induced cytokine production, coagulation disturbances, and mortality.
Topics: Animals; Antithrombin III; Blood Coagulation Disorders; Bronchodilator Agents; Cytokines; Dose-Response Relationship, Drug; Endotoxins; Leukocytes; Male; Pentoxifylline; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1996 |
Effects on complement activation and cytokine (TNF-alpha and IL-8) release of infusion of anti-TNF-antibodies or a xanthine derivative (HWA 138) in septic baboons.
Topics: Animals; Antibodies; Complement Activation; Complement Membrane Attack Complex; Escherichia coli Infections; Hemodynamics; Interleukin-8; Male; Papio; Pentoxifylline; Sepsis; Tumor Necrosis Factor-alpha; Xanthines | 1996 |
Inhibition of LPS and Plasmodium falciparum induced cytokine secretion by pentoxifylline and two analogues.
Topics: Adult; Animals; Cytokines; Female; Humans; In Vitro Techniques; Interleukin-1; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Pentoxifylline; Phosphodiesterase Inhibitors; Plasmodium falciparum; Tumor Necrosis Factor-alpha | 1997 |
Regional perfusion and oxygenation of tumors upon methylxanthine derivative administration.
Topics: Animals; Male; Neoplasms, Experimental; Oxygen Consumption; Pentoxifylline; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sarcoma, Experimental; Vasodilator Agents | 1998 |