huperzine a has been researched along with physostigmine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (23.81) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 9 (42.86) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Brossi, A; Greig, NH; Holloway, HW; Whittaker, NF; Yu, QS; Zhu, X | 1 |
| Brossi, A; Greig, NH; Holloway, HW; Kulkarni, SS; Lahiri, DK; Luo, W; Parrish, DA; Shafferman, A; Tweedie, D; Yu, QS | 1 |
| Corey, J; Hanin, I; Laganière, S; Tang, XC; Wülfert, E | 1 |
| Chen, SS; Guan, LC; Lu, WH; Tang, XC | 1 |
| Chen, XP; Han, YF; Tang, XC; Zhu, XD | 1 |
| Lu, WH; Shou, J; Tang, XC | 1 |
| Chen, SM; Xue, ZG | 1 |
| Tang, XC; Zhu, XD | 1 |
| Feng, J; Liu, JS; Tang, XC; Xu, H; Zhou, TX | 1 |
| Ashani, Y; Doctor, BP; Grunwald, J; Raveh, L | 1 |
| Ariel, N; Barak, D; Bino, T; Ordentlich, A; Shafferman, A; Velan, B | 1 |
| Cheng, DH; Tang, XC; Xiong, ZQ | 1 |
| Kaur, J; Zhang, MQ | 1 |
| Aubriot, S; Baubichon, D; Carpentier, P; Dorandeu, F; Foquin, A; Lallement, G | 1 |
| Baubichon, D; Carpentier, P; Dorandeu, F; Foquin, A; Lallement, G | 1 |
| Tang, XC; Zhao, Q | 1 |
| Houghton, PJ; Howes, MJ; Perry, NS | 1 |
| Buerki, RA; Patil, KD; Patil, PN | 1 |
| Eckert, S; Eyer, P; Mückter, H; Worek, F | 1 |
| Cesario, A; Del Bufalo, A; Fini, M; Frustaci, A; Russo, P | 1 |
| Curtis, MA; Lin, SX; Sperry, J | 1 |
4 review(s) available for huperzine a and physostigmine
| Article | Year |
|---|---|
Molecular modelling and QSAR of reversible acetylcholines-terase inhibitors.
Topics: Alkaloids; Alzheimer Disease; Cholinesterase Inhibitors; Crystallography, X-Ray; Donepezil; Drug Design; Glaucoma; Humans; Indans; Models, Molecular; Myasthenia Gravis; Neostigmine; Physostigmine; Piperidines; Sesquiterpenes; Structure-Activity Relationship; Surface Properties; Tacrine | 2000 |
Plants with traditional uses and activities, relevant to the management of Alzheimer's disease and other cognitive disorders.
Topics: Alkaloids; Alzheimer Disease; Estrogens, Non-Steroidal; Galantamine; Humans; Isoflavones; Physostigmine; Phytoestrogens; Phytotherapy; Plant Extracts; Plant Preparations; Plants, Medicinal; Sesquiterpenes | 2003 |
Multitarget drugs of plants origin acting on Alzheimer's disease.
Topics: Alkaloids; Alzheimer Disease; Animals; Biological Products; Cholinesterase Inhibitors; Crocus; Drug Discovery; Galantamine; Galanthus; Ginkgo biloba; Humans; Huperzia; Neuroprotective Agents; Physostigmine; Plant Extracts; Plants; Salvia; Sesquiterpenes | 2013 |
Pyridine alkaloids with activity in the central nervous system.
Topics: Alkaloids; Amphibians; Animals; Bacteria; Central Nervous System Diseases; Fungi; Nicotine; Plants; Pyridines; Receptors, Nicotinic | 2020 |
17 other study(ies) available for huperzine a and physostigmine
| Article | Year |
|---|---|
Anticholinesterase activity of compounds related to geneserine tautomers. N-Oxides and 1,2-oxazines.
Topics: Acetylcholinesterase; Alkaloids; Butyrylcholinesterase; Cholinesterase Inhibitors; Cyclic N-Oxides; Humans; Isomerism; Oxazines; Structure-Activity Relationship | 2002 |
Inhibition of human acetyl- and butyrylcholinesterase by novel carbamates of (-)- and (+)-tetrahydrofurobenzofuran and methanobenzodioxepine.
Topics: Acetophenones; Acetylcholinesterase; Animals; Benzofurans; Butyrylcholinesterase; Carbamates; Cholinesterase Inhibitors; Crystallography, X-Ray; Furans; Heterocyclic Compounds, 3-Ring; Humans; Models, Molecular; Oxepins; Stereoisomerism; Structure-Activity Relationship; Torpedo | 2006 |
Acute and chronic studies with the anticholinesterase Huperzine A: effect on central nervous system cholinergic parameters.
Topics: Acetylcholinesterase; Alkaloids; Animals; Brain; Choline; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Physostigmine; Rats; Rats, Inbred Strains; Sesquiterpenes | 1991 |
[Effects of huperzine A on electroencephalography power spectrum in rabbits].
Topics: Alkaloids; Animals; Electroencephalography; Male; Physostigmine; Rabbits; Scopolamine; Sesquiterpenes; Signal Processing, Computer-Assisted | 1989 |
[Effects of huperzine A on learning and the retrieval process of discrimination performance in rats].
Topics: Alkaloids; Animals; Atropine; Discrimination Learning; Hemicholinium 3; Male; Memory; Physostigmine; Rats; Scopolamine; Sesquiterpenes | 1986 |
[Improving effect of huperzine A on discrimination performance in aged rats and adult rats with experimental cognitive impairment].
Topics: Aging; Alkaloids; Animals; Cholinesterase Inhibitors; Discrimination Learning; Female; Lighting; Male; Memory; Physostigmine; Rats; Sesquiterpenes | 1988 |
[The effect of fordine on learning and memory in rats].
Topics: Alkaloids; Animals; Avoidance Learning; Cholinesterase Inhibitors; Female; Male; Memory; Physostigmine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Scopolamine Derivatives | 1987 |
[Facilitatory effects of huperzine A and B on learning amd memory of spatial discrimination in mice].
Topics: Alkaloids; Animals; Cholinesterase Inhibitors; Discrimination Learning; Male; Memory; Mice; Physostigmine; Sesquiterpenes | 1987 |
Effect of cholinesterase inhibition in vitro by huperzine analogs.
Topics: Acetylcholinesterase; Alkaloids; Animals; Cholinesterase Inhibitors; Erythrocyte Membrane; Galantamine; Physostigmine; Rats; Sesquiterpenes; Structure-Activity Relationship | 1994 |
Huperzine A as a pretreatment candidate drug against nerve agent toxicity.
Topics: Acetylcholinesterase; Alkaloids; Animals; Antidotes; Binding Sites; Brain; Cholinesterase Inhibitors; Injections, Intraperitoneal; Kinetics; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Physostigmine; Poisoning; Sesquiterpenes; Soman; Time Factors | 1994 |
The 'aromatic patch' of three proximal residues in the human acetylcholinesterase active centre allows for versatile interaction modes with inhibitors.
Topics: Acetylcholinesterase; Alkaloids; Binding Sites; Cholinesterase Inhibitors; Crystallography, X-Ray; Humans; Hydrogen Bonding; Kinetics; Ligands; Models, Chemical; Models, Molecular; Physostigmine; Protein Conformation; Pyridostigmine Bromide; Sesquiterpenes; Structure-Activity Relationship; Tacrine | 1998 |
Effects of huperzine A on nucleus basalis magnocellularis lesion-induced spatial working memory deficit.
Topics: Alkaloids; Animals; Cerebral Cortex; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Kainic Acid; Male; Maze Learning; Physostigmine; Rats; Rats, Sprague-Dawley; Retention, Psychology; Sesquiterpenes; Substantia Innominata | 1998 |
Subchronic administration of various pretreatments of nerve agent poisoning. I. Protection of blood and central cholinesterases, innocuousness towards blood-brain barrier permeability.
Topics: Alkaloids; Animals; Blood-Brain Barrier; Brain; Cholinesterase Inhibitors; Cholinesterases; Erythrocytes; Evans Blue; Guinea Pigs; Male; Microscopy, Fluorescence; Neuroprotective Agents; Physostigmine; Pyridostigmine Bromide; Serum Albumin; Sesquiterpenes | 2001 |
Subchronic administration of various pretreatments of nerve agent poisoning. II. Compared efficacy against soman toxicity.
Topics: Alkaloids; Animals; Cholinesterase Inhibitors; Electroencephalography; Guinea Pigs; Male; Neuroprotective Agents; Physostigmine; Pyridostigmine Bromide; Scopolamine; Seizures; Sesquiterpenes; Soman; Time Factors | 2001 |
Effects of huperzine A on acetylcholinesterase isoforms in vitro: comparison with tacrine, donepezil, rivastigmine and physostigmine.
Topics: Acetylcholinesterase; Alkaloids; Animals; Carbamates; Cerebral Cortex; Cholinesterase Inhibitors; Corpus Striatum; Donepezil; Hippocampus; Indans; Isoenzymes; Kinetics; Male; Phenylcarbamates; Physostigmine; Piperidines; Rats; Rats, Sprague-Dawley; Rivastigmine; Sesquiterpenes; Tacrine | 2002 |
Potentiation of acetylcholine action by huperzine-A and physostigmine on some vertebrate effectors, including human iris sphincter muscle.
Topics: Acetylcholine; Alkaloids; Animals; Cholinesterase Inhibitors; Diaphragm; Drug Synergism; Guinea Pigs; Humans; Ileum; Iris; Muscle, Smooth; Muscles; Neuromuscular Junction; Phrenic Nerve; Physostigmine; Rana catesbeiana; Rats; Rectus Abdominis; Sesquiterpenes | 2003 |
Kinetic analysis of the protection afforded by reversible inhibitors against irreversible inhibition of acetylcholinesterase by highly toxic organophosphorus compounds.
Topics: Acetylcholinesterase; Algorithms; Alkaloids; Carbamates; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Erythrocytes; Humans; Kinetics; Organophosphorus Compounds; Paraoxon; Physostigmine; Pyridostigmine Bromide; Sesquiterpenes; Time Factors | 2006 |