Compounds > huperzine a

huperzine a and huprine y

huperzine a has been researched along with huprine y in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Badia, A; Camps, P; Clos, MV; Formosa, X; Muñoz-Torrero, D; Petrignet, J1
Alcalá, Mdel M; Badia, A; Camps, P; Hospital, S; Muñoz-Torrero, D; Vivas, NM1
Camins, A; Camps, P; Canudas, AM; Jiménez, A; Jordá, EG; Muñoz-Torrero, D; Pallàs, M; Rimbau, V; Verdaguer, E1
Badia, A; Camps, P; Clos, MV; Colombo, L; Manzoni, C; Muñoz-Torrero, D; Pera, M; Ratia, M; Román, S; Salmona, M1
Badia, A; Camps, P; Clos, MV; Curutchet, C; Gómez, E; Luque, FJ; Muñoz-Muriedas, J; Muñoz-Torrero, D1

Other Studies

5 other study(ies) available for huperzine a and huprine y

ArticleYear
Synthesis and pharmacological evaluation of huprine-tacrine heterodimers: subnanomolar dual binding site acetylcholinesterase inhibitors.
    Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6

    Topics: Acetylcholinesterase; Aminoquinolines; Animals; Binding Sites; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Heterocyclic Compounds, 4 or More Rings; Humans; Structure-Activity Relationship; Tacrine

2005
Characterisation of the anticholinesterase activity of two new tacrine-huperzine A hybrids.
    Neuropharmacology, 2003, Volume: 44, Issue:6

    Topics: Alkaloids; Aminoquinolines; Animals; Brain; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship; Tacrine

2003
(+/-)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration.
    Journal of Alzheimer's disease : JAD, 2004, Volume: 6, Issue:6

    Topics: Alkaloids; Alzheimer Disease; Aminoquinolines; Animals; Animals, Newborn; Apoptosis; Cerebellum; Cholinesterase Inhibitors; Colchicine; Cytoskeleton; Disease Models, Animal; Flow Cytometry; Glycogen Synthase Kinase 3; Heterocyclic Compounds, 4 or More Rings; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tacrine

2004
Acetylcholinesterase triggers the aggregation of PrP 106-126.
    Biochemical and biophysical research communications, 2006, Jul-21, Volume: 346, Issue:1

    Topics: Acetylcholinesterase; Alkaloids; Aminoquinolines; Animals; Cattle; Cholinesterase Inhibitors; Coumarins; Heterocyclic Compounds, 4 or More Rings; Humans; Microscopy, Fluorescence; Peptide Fragments; Prions; Propidium; Protein Structure, Secondary; Sesquiterpenes

2006
Binding of 13-amidohuprines to acetylcholinesterase: exploring the ligand-induced conformational change of the gly117-gly118 peptide bond in the oxyanion hole.
    Journal of medicinal chemistry, 2006, Nov-16, Volume: 49, Issue:23

    Topics: Acetylcholinesterase; Alkaloids; Aminoquinolines; Animals; Anions; Catalytic Domain; Cattle; Cholinesterase Inhibitors; Erythrocytes; Formamides; Glycine; Heterocyclic Compounds, 4 or More Rings; Humans; Ligands; Models, Molecular; Protein Binding; Protein Conformation; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Tacrine

2006