Page last updated: 2024-09-03

hrp 102 and medroxyprogesterone acetate

hrp 102 has been researched along with medroxyprogesterone acetate in 17 studies

Compound Research Comparison

Studies
(hrp 102)
Trials
(hrp 102)
Recent Studies (post-2010)
(hrp 102)
Studies
(medroxyprogesterone acetate)
Trials
(medroxyprogesterone acetate)
Recent Studies (post-2010) (medroxyprogesterone acetate)
331985,1231,1151,099

Protein Interaction Comparison

ProteinTaxonomyhrp 102 (IC50)medroxyprogesterone acetate (IC50)
Estrogen receptorHomo sapiens (human)0.924
Glucocorticoid receptorHomo sapiens (human)0.013
Progesterone receptorHomo sapiens (human)2.5081
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)0.019
Mineralocorticoid receptor Homo sapiens (human)1.197
Androgen receptorHomo sapiens (human)0.0061
Androgen receptorRattus norvegicus (Norway rat)0.279
Glycine receptor subunit betaRattus norvegicus (Norway rat)0.019
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)0.019
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)0.019
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)1.197
Aldo-keto reductase family 1 member C3Homo sapiens (human)1.4059
Aldo-keto reductase family 1 member C2 Homo sapiens (human)4.0405
Aldo-keto reductase family 1 member C1Homo sapiens (human)1.8
Estrogen receptor betaHomo sapiens (human)0.924

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.76)18.7374
1990's12 (70.59)18.2507
2000's1 (5.88)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdel-Sayed, WS; Darwish, EA; el-Habashy, MA; Haiba, NA; Nayel, SE; Said, SA1
Aedo, AR; Diczfalusy, E; Johannisson, E; Landgren, BM1
Chen, JK; Chen, SF; Fang, KJ; Ge, JL; Ge, RS; He, ML; Luo, SY; Sang, GW; Shao, QX; Song, S2
Bassol, S; Hernandez, C; Luz de la Cruz, D; Nava, MP; Trujillo, AM1
Toppozada, MK1
Sang, GW1
Koetsawang, S1
el-Hussein, M; el-Nahal, N; Hassan, EO1
el Houssinie, M; el Nahal, N; Hassan, EO1
el-Hussinie, M; el-Nahal, N; Hassan, EO1
Cunha, EP; Fernandes, CE; Mader, AM; Pinhal, MA; Pompei, LM; Silva, VF; Silveira, ER; Steiner, ML; Theodoro, TR1
Cunha, EP; Fernandes, CE; Mader, AM; Petri, G; Pinhal, MA; Pompei, LM; Steiner, ML; Theodoro, TR1

Reviews

4 review(s) available for hrp 102 and medroxyprogesterone acetate

ArticleYear
Existing once-a-month combined injectable contraceptives.
    Contraception, 1994, Volume: 49, Issue:4

    Topics: Algestone Acetophenide; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Delayed-Action Preparations; Drug Combinations; Estradiol; Female; Humans; Injections, Intramuscular; Medroxyprogesterone Acetate; Norethindrone

1994
Pharmacodynamic effects of once-a-month combined injectable contraceptives.
    Contraception, 1994, Volume: 49, Issue:4

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Algestone Acetophenide; China; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Delayed-Action Preparations; Drug Combinations; Estradiol; Female; Humans; Hydroxyprogesterones; Injections, Intramuscular; Latin America; Medroxyprogesterone Acetate; Norethindrone

1994
Once-a-month injectable contraceptives: efficacy and reasons for discontinuation.
    Contraception, 1994, Volume: 49, Issue:4

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Algestone Acetophenide; Clinical Trials, Phase III as Topic; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Delayed-Action Preparations; Drug Combinations; Estradiol; Female; Humans; Hydroxyprogesterones; Injections, Intramuscular; Medroxyprogesterone Acetate; Multicenter Studies as Topic; Norethindrone; Randomized Controlled Trials as Topic

1994
Facts about once-a-month injectable contraceptives: memorandum from a WHO meeting.
    Bulletin of the World Health Organization, 1993, Volume: 71, Issue:6

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Animals; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Delayed-Action Preparations; Drug Combinations; Drug Evaluation; Estradiol; Estrogen Antagonists; Estrogens, Conjugated (USP); Female; Humans; Hydroxyprogesterones; Injections, Intramuscular; Medroxyprogesterone Acetate; Norethindrone; World Health Organization

1993

Trials

9 trial(s) available for hrp 102 and medroxyprogesterone acetate

ArticleYear
Clinical evaluation of two monthly injectable contraceptives and their effects on some metabolic parameters.
    Contraception, 1989, Volume: 39, Issue:6

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Blood Proteins; Body Weight; Clinical Trials as Topic; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Drug Combinations; Estradiol; Female; Humans; Injections, Intramuscular; Lipids; Medroxyprogesterone; Medroxyprogesterone Acetate; Menstruation; Norethindrone

1989
A multicentred phase III comparative clinical trial of Mesigyna, Cyclofem and Injectable No. 1 given monthly by intramuscular injection to Chinese women. I. Contraceptive efficacy and sid effects.
    Contraception, 1995, Volume: 51, Issue:3

    Topics: Adolescent; Adult; Amenorrhea; Blood Pressure; Body Weight; China; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Dose-Response Relationship, Drug; Drug Combinations; Estradiol; Female; Humans; Hydroxyprogesterones; Injections, Intramuscular; Medroxyprogesterone Acetate; Menstrual Cycle; Menstruation Disturbances; Norethindrone; Patient Dropouts

1995
A multicentred phase III comparative clinical trial of Mesigyna, Cyclofem and Injectable No. 1 given by intramuscular injection to Chinese women. II. The comparison of bleeding patterns.
    Contraception, 1995, Volume: 51, Issue:3

    Topics: Adolescent; Adult; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Dose-Response Relationship, Drug; Drug Combinations; Estradiol; Female; Humans; Hydroxyprogesterones; Injections, Intramuscular; Medroxyprogesterone Acetate; Menstrual Cycle; Menstruation Disturbances; Norethindrone

1995
A comparative study on the return to ovulation following chronic use of once-a-month injectable contraceptives.
    Contraception, 1995, Volume: 51, Issue:5

    Topics: Adult; Contraceptives, Oral, Combined; Drug Combinations; Estradiol; Estrone; Female; Glucuronates; Humans; Injections, Intramuscular; Kinetics; Medroxyprogesterone Acetate; Mexico; Norethindrone; Ovulation; Pregnanediol

1995
Acceptability of the once-a-month injectable contraceptives Cyclofem and Mesigyna in Egypt.
    Contraception, 1994, Volume: 49, Issue:5

    Topics: Attitude; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Delayed-Action Preparations; Drug Combinations; Egypt; Estradiol; Female; Humans; Marriage; Medroxyprogesterone Acetate; Norethindrone; Patient Satisfaction; Retrospective Studies; Surveys and Questionnaires

1994
Comparative study of the effects of two once-a-month injectable steroidal contraceptives (Mesigyna and Cyclofem) on lipid and lipoprotein metabolism. United Nations Development Programme/United Nations Population Fund/World Health Organization/World Bank,
    Contraception, 1997, Volume: 56, Issue:4

    Topics: Adult; Cholesterol; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Drug Administration Schedule; Drug Combinations; Estradiol; Female; Follow-Up Studies; Humans; Injections; Lipids; Lipoproteins; Longitudinal Studies; Medroxyprogesterone Acetate; Norethindrone; Triglycerides

1997
Comparative study of the effects of two once-a-month injectable steroidal contraceptives (Mesigyna and Cyclofem) on glucose metabolism and liver function. United Nations Development Programme/United Population Fund/World Health Organization/World Bank, Sp
    Contraception, 1998, Volume: 57, Issue:2

    Topics: Adolescent; Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Blood Glucose; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Drug Combinations; Estradiol; Female; gamma-Glutamyltransferase; Glucose Tolerance Test; Humans; Injections; Liver; Longitudinal Studies; Medroxyprogesterone Acetate; Norethindrone

1998
Once-a-month injectable contraceptives, Cyclofem and Mesigyna, in Egypt. Efficacy, causes of discontinuation, and side effects.
    Contraception, 1999, Volume: 60, Issue:2

    Topics: Adult; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Drug Administration Schedule; Drug Combinations; Egypt; Estradiol; Female; Humans; Injections, Intravenous; Medroxyprogesterone Acetate; Norethindrone; Patient Compliance; Weight Gain

1999
Comparative study of the effects of two once-a-month injectable contraceptives (Cyclofem and Mesigyna) and one oral contraceptive (Ortho-Novum 1/35) on coagulation and fibrinolysis.
    Contraception, 2003, Volume: 68, Issue:3

    Topics: Adolescent; Adult; Antithrombins; Blood Coagulation; Cardiovascular Diseases; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Drug Combinations; Estradiol; Factor VII; Factor X; Female; Fibrinogen; Fibrinolysis; Hemoglobins; Humans; Injections; Medroxyprogesterone Acetate; Mestranol; Norethindrone; Partial Thromboplastin Time; Plasminogen; Plasminogen Inactivators; Platelet Count; Protein C; Prothrombin

2003

Other Studies

4 other study(ies) available for hrp 102 and medroxyprogesterone acetate

ArticleYear
Pharmacokinetic and pharmacodynamic investigations with monthly injectable contraceptive preparations.
    Contraception, 1985, Volume: 31, Issue:5

    Topics: Adult; Biopsy; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Delayed-Action Preparations; Drug Combinations; Endometrium; Estradiol; Female; Humans; Injections; Kinetics; Medroxyprogesterone; Medroxyprogesterone Acetate; Menstruation; Norethindrone; Ovulation; Progesterone

1985
Acceptability of once-a-month injectable contraceptives Cyclofem and Mesigyna: focus group discussion.
    Contraception, 1999, Volume: 59, Issue:6

    Topics: Adult; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Counseling; Drug Combinations; Egypt; Estradiol; Female; Focus Groups; Humans; Islam; Medroxyprogesterone Acetate; Norethindrone; Patient Satisfaction; Social Support

1999
Is expression of rat breast matrix components influenced by estrogen, progestins and tibolone?
    Climacteric : the journal of the International Menopause Society, 2015, Volume: 18, Issue:4

    Topics: Animals; Biomarkers; Breast; Cell Proliferation; Drug Combinations; Dydrogesterone; Estradiol; Estrogen Receptor Modulators; Estrogens; Extracellular Matrix; Female; Glucuronidase; Heparan Sulfate Proteoglycans; Immunohistochemistry; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Medroxyprogesterone Acetate; Norethindrone; Norpregnenes; Progestins; Proliferating Cell Nuclear Antigen; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction

2015
Effects of estradiol, progestogens, and of tibolone on breast proliferation and apoptosis.
    Climacteric : the journal of the International Menopause Society, 2015, Volume: 18, Issue:4

    Topics: Animals; Apoptosis; Breast; Cell Proliferation; Drug Combinations; Dydrogesterone; Estradiol; Estrogen Receptor Modulators; Estrogens; Female; Medroxyprogesterone Acetate; Norethindrone; Norpregnenes; Progestins; Random Allocation; Rats; Rats, Wistar

2015