horsfiline and nitromethane

horsfiline has been researched along with nitromethane* in 1 studies

Other Studies

1 other study(ies) available for horsfiline and nitromethane

Article	Year
Asymmetric organocatalyzed Michael addition of nitromethane to a 2-oxoindoline-3-ylidene acetaldehyde and the three one-pot sequential synthesis of (-)-horsfiline and (-)-coerulescine. Chemistry (Weinheim an der Bergstrasse, Germany), 2014, Oct-13, Volume: 20, Issue:42 (-)-Horsfiline and (-)-coerulescine were synthesized through three one-pot operations in 33 and 46% overall yield, respectively. Key to the success was the efficient use of a diarylprolinol silyl ether to catalyze the asymmetric Michael addition of nitromethane to a 2-oxoindoline-3-ylidene acetaldehyde. This allowed the all-carbon quaternary, spirocyclic carbon stereocenter to be constructed in good yield with excellent enantioselectivity. Topics: Acetaldehyde; Aniline Compounds; Catalysis; Methane; Nitroparaffins; Spiro Compounds; Stereoisomerism	2014

Article

Year

Asymmetric organocatalyzed Michael addition of nitromethane to a 2-oxoindoline-3-ylidene acetaldehyde and the three one-pot sequential synthesis of (-)-horsfiline and (-)-coerulescine.

Chemistry (Weinheim an der Bergstrasse, Germany), 2014, Oct-13, Volume: 20, Issue:42

(-)-Horsfiline and (-)-coerulescine were synthesized through three one-pot operations in 33 and 46% overall yield, respectively. Key to the success was the efficient use of a diarylprolinol silyl ether to catalyze the asymmetric Michael addition of nitromethane to a 2-oxoindoline-3-ylidene acetaldehyde. This allowed the all-carbon quaternary, spirocyclic carbon stereocenter to be constructed in good yield with excellent enantioselectivity.

Topics: Acetaldehyde; Aniline Compounds; Catalysis; Methane; Nitroparaffins; Spiro Compounds; Stereoisomerism

2014