homovanillic acid has been researched along with oxidopamine in 172 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (20.93) | 18.7374 |
| 1990's | 67 (38.95) | 18.2507 |
| 2000's | 49 (28.49) | 29.6817 |
| 2010's | 20 (11.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| James, TA; Straughan, DW | 1 |
| Jenner, P; Marsden, CD; Rose, S; Thomas, KL | 1 |
| Connor, DJ; Dietz, S; Langlais, PJ; Thal, LJ | 1 |
| Finch, CE; Kelly, AB; Kohama, S; Morgan, DG; Osterburg, HH; Pasinetti, GM; Reinhard, JF; Stellwagen, RH | 1 |
| Crock, R; Pehek, EA; Yamamoto, BK | 1 |
| Huston, JP; Mattioli, R; Schwarting, RK | 1 |
| Castañeda, E; Fiorino, D; Mittleman, G; Whishaw, IQ | 1 |
| De Klippel, N; Deleu, D; Devrieze, A; Ebinger, G; Herregodts, P; Michotte, Y; Sarre, S | 1 |
| Borrelli, E; Haby, C; Hindelang, C; Lisovoski, F; Revel, MO; Schleef, C; Zwiller, J | 1 |
| Castañeda, E; Robinson, TE; Whishaw, IQ | 1 |
| Bledsoe, S; Murphy, J; Zhou, FC | 1 |
| Parker, GC; Rugg, EL; Winn, P | 1 |
| Costentin, J; Naudin, B; Saligaut, C | 1 |
| Bédard, PJ; Di Paolo, T; Gagnon, C; Gaudin, DP; Rioux, L | 1 |
| Carey, RJ | 2 |
| Ben-Shachar, D; Eshel, G; Finberg, JP; Youdim, MB | 1 |
| Drumheller, A; Jolicoeur, FB; Rivest, R; St-Pierre, S | 1 |
| Drumheller, A; Jolicoeur, FB; Rivest, R | 1 |
| Hashiguchi, H; Hashitani, T; Ikeda, T; Ishida, Y; Nishino, H; Yamamoto, R | 1 |
| Bhardwaj, A; Brannan, T; Martinez-Tica, J; Weinberger, J; Yahr, M | 1 |
| Abercrombie, ED; Keefe, KA; Stricker, EM; Zigmond, MJ | 1 |
| Gale, K; Meloni, R | 1 |
| Brannan, T; Kaufmann, H; Knott, P; Yahr, M | 1 |
| Curzon, G; Hutson, PH | 1 |
| Bradbury, AJ; Costall, B; Domeney, AM; Jenner, PJ; Marsden, CD; Naylor, RJ | 1 |
| Baldessarini, RJ; Barber, NI; Finklestein, SP; Reichheld, JH; Teicher, MH | 1 |
| Alvarez, C; Berger, B; McRae-Degueurce, A; Milon, H; Ornstein, K; Würzner, HP | 1 |
| Camarota, NA; Glick, SD; Shapiro, RM | 1 |
| Ballarin, M; Casas, M; Herrera-Marschitz, M; Ungerstedt, U | 1 |
| Adams, F; Becker, JB; Robinson, TE | 1 |
| Cadet, JL; Fahn, S; Jackson-Lewis, V; Katz, M | 1 |
| Carey, RJ; Lynch, MR | 2 |
| Greenshaw, AJ; Juorio, AV; Nguyen, TV | 1 |
| Altar, CA; Marien, MR | 1 |
| Chung, E; Dvorozniak, MT; Li, HC; Van Woert, MH | 1 |
| Edwards, DJ; Knopf, S; Ravitch, J; Sedlock, ML | 1 |
| Enz, A; Hefti, F; Melamed, E | 1 |
| Busto, R; Dietrich, WD; Ginsberg, MD; Globus, MY; Martinez, E; Valdes, I | 1 |
| Bédard, P; Di Paolo, T; Falardeau, P; Rouillard, C | 1 |
| Brunette, JR; Drumheller, AL; Jolicoeur, FB; Lafond, G; Olivier, P | 1 |
| Fibiger, HC; Jakubovic, A; LePiane, FG; Phillips, AG | 1 |
| Janowsky, A; Kim, YS; Koulu, M; Labarca, R; Linnoila, M; Paul, SM; Pickar, D; Thomas, JW; Wilkinson, L | 1 |
| Robinson, TE; Whishaw, IQ | 1 |
| Baird, JL; Glick, SD; Hinds, PA | 1 |
| Hong, JS; Hudson, PM; Nanry, KP; Stachowiak, MK; Tilson, HA; Zhang, WQ | 1 |
| Radhakishun, FS; van Ree, JM; Wolterink, G | 1 |
| Fillenz, M; O'Neill, RD | 1 |
| Forler, C; Palfreyman, MG; Robin, M | 1 |
| Buu, NT | 1 |
| Hefti, F; Melamed, E; Wurtman, RJ | 1 |
| Dravid, A; Enz, A; Frei, P; Jaton, AL | 1 |
| Feenstra, MG; Horn, AS; Mulder, TB; Rollema, H; Westerink, BH | 1 |
| Korf, J; Sebens, JB; Vaalburg, W; van der Werf, JF | 1 |
| Burgess, SK; Kalivas, PW; Nemeroff, CB; Prange, AJ | 1 |
| Altar, CA; Marshall, JF; O'Neil, S | 1 |
| Bruneau, N; Cottet-Emard, JM; Le Moal, M; Peyrin, L; Simon, H | 1 |
| Gramsbergen, JB; Sloot, WN; van der Sluijs-Gelling, AJ | 1 |
| Camp, DM; Mocsary, Z; Robinson, TE; Whishaw, IQ | 1 |
| Altar, CA; Boylan, CB; Fritsche, M; Hyman, C; Jackson, C; Jones, BE; Lindsay, RM; Wiegand, SJ | 1 |
| Finlay, JM; King, D | 1 |
| Amalric, M; Daszuta, A; Moukhles, H; Nieoullon, A | 1 |
| Bankiewicz, KS; Finberg, JP; Goldstein, DS; Kopin, IJ; Wang, J | 1 |
| Loupe, PS; Schroeder, SR; Stodgell, CJ; Tessel, RE | 1 |
| Boix, F; Fornaguera, J; Huston, JP; Schwarting, RK | 1 |
| Bickford, P; Friedemann, M; Gerhardt, GA; Hoffer, BJ; Luthman, J; Olson, L | 1 |
| Castello, ME; Costa, G; Dajas, F; Greenfield, S; Jerusalinsky, D; Levesque, D; Medina, J; Silveira, R | 1 |
| Brannan, T; Martínez-Tica, J; Yahr, MD | 1 |
| Ambrosio, S; Bartrons, R; Calopa, M; Espino, A; Llorens, J; Rodriguez-Farré, E | 1 |
| Carey, RJ; Dai, H; Huston, JP; Pinheiro-Carrera, M; Tomaz, C | 1 |
| Fuller, RW; Hemrick-Luecke, SK; Snoddy, HD | 1 |
| Brodin, E; Goiny, M; Herrera-Marschitz, M; Hökfelt, T; Meana, JJ; Morino, P; Silveira, R; Ungerstedt, U; You, ZB | 1 |
| Gayrard, V; Malpaux, B; Thiéry, JC; Tillet, Y | 1 |
| De Klippel, N; Ebinger, G; Herregodts, P; Michotte, Y; Sarre, S | 1 |
| Bubser, M | 1 |
| Asanuma, M; Kawada, Y; Kondo, Y; Mori, A; Ogawa, N; Yamamoto, M | 1 |
| Bruno, JP; Garity, D; Sidhu, KS; Stellar, JR | 1 |
| De Klippel, N; Ebinger, G; Michotte, Y; Sarre, S | 1 |
| Hossain, MA; Weiner, N | 1 |
| Salamone, JD; Steinpreis, RE | 1 |
| Daugé, V; Derrien, M; Durieux, C; Roques, BP | 1 |
| McCullough, LD; Salamone, JD; Sokolowski, JD | 1 |
| Ambrosio, S; Bartrons, R; Cutillas, B; Espino, A; Ferrer, I; Tortosa, A | 1 |
| Godukhin, O; Goiny, M; Herrera-Marschitz, M; Hökfelt, T; Kehr, J; Nylander, I; Pettersson, E; Shou, HZ; Terenius, L; Ungerstedt, U; You, ZB | 1 |
| Kabuto, H; Makino, H; Matsuura, K; Ogawa, N | 1 |
| Chiou, AL; Tang, FI; Wang, JY; Wang, Y | 1 |
| Hashitani, T; Hattori, S; Matsui, N; Nishino, H | 1 |
| Emmi, A; Rajabi, H; Stewart, J | 1 |
| Makino, H; Matsuura, K; Ogawa, N | 1 |
| Blunt, SB; Hötten, G; Opacka-Juffry, J; Pohl, J; Sullivan, AM | 1 |
| Alvarez, P; Cruz, R; Garciá, JC; Leiva, A; McPherson, M; Soto, Y | 1 |
| Okada, S; Sawashita, J; Takeda, A; Takefuta, S | 1 |
| Hashitani, T; Kumazaki, M; Mizukawa, K; Nishino, H | 1 |
| Andersen, SL; Baldessarini, RJ; Campbell, A; Gelbard, HA; Teicher, MH | 1 |
| Ebinger, G; Izurieta-Sánchez, P; Michotte, Y; Sarre, S | 1 |
| Blunt, SB; Opacka-Juffry, J; Sullivan, AM | 1 |
| Chen, CF; Chueh, FS; Chueh, FY; Hsieh, MT; Lin, MT; Lin, SM | 1 |
| Damhaut, P; Dethy, S; Goldman, S; Laute, MA | 1 |
| Beyer, CE; Steketee, JD | 1 |
| Finlay, JM; Lewis, DA; Venator, DK | 1 |
| Iwata-Ichikawa, E; Kabuto, H; Ogawa, N; Yokoi, I | 1 |
| Gentsch, C; Spooren, WP; Waldmeier, P | 1 |
| Kannari, K; Maeda, T; Matsunaga, M; Suda, T; Tanaka, H; Tomiyama, M | 1 |
| Carvey, PM; Collier, TJ; Ling, ZD; Lipton, JW; Robie, HC; Sortwell, CE; Vu, TQ | 1 |
| Goldstein, DS; Harvey-White, JD; Kopin, IJ; Yadid, G | 1 |
| Kupsch, A; Meissner, W; Morgenstern, R; Paul, G; Reese, R; Reum, T; Sohr, R | 1 |
| Jenner, P; Rose, S; Treseder, SA | 1 |
| Halladay, AK; Michna, L; Wagner, GC; Widmer, DA; Yue, Y; Zhou, R | 1 |
| Bell, KP; Choi, PK; Clarkson, ED; Esplen, JE; Freed, CR; Heidenreich, KA; Zawada, WM | 1 |
| Baklaushev, VP; Chekhonin, VP; Dmitrieva, TB; Filatova, TS; Kogan, BM; Lebedev, SV; Man'kovskaya, IV; Savchenko, EA; Yusupova, IU | 1 |
| Dentresangle, C; Le Cavorsin, M; Leviel, V; Savasta, M | 1 |
| Al Deeb, S; Al Moutaery, K; Khan, HA; Tariq, M | 1 |
| Harnack, D; Kupsch, A; Meissner, W; Morgenstern, R; Paul, G; Reum, T; Sohr, R | 1 |
| Cohen, AD; Miller, GW; Philhower, J; Schallert, T; Tillerson, JL; Zigmond, MJ | 1 |
| Ferger, B; Schmidt, N; Schulz, JB; Teismann, P; Xia, XG | 1 |
| Barthwal, MK; Dikshit, M; Srivastava, N | 1 |
| Aguiar, LM; Sousa, FC; Vasconcelos, SM; Viana, GS | 1 |
| Caudle, WM; Cohen, AD; Miller, GW; Schallert, T; Tillerson, JL; Zigmond, MJ | 1 |
| Cimini, MG; Haas, JV; Nichols, NF; Staton, BA; Svensson, KA; Tedroff, J | 1 |
| Datla, KP; Dexter, DT; Gillies, GE; Murray, HE; Pillai, AV | 1 |
| Schmidt, WJ; Srinivasan, J | 2 |
| Ben Shachar, D; Stephenson, G; Youdim, MB | 1 |
| Finberg, JP; Gross, A; Moses, D | 1 |
| Gluck, MR; Granson, H; Santana, LA; Yahr, MD | 1 |
| Moroz, IA; Peciña, S; Schallert, T; Stewart, J | 1 |
| Harsing, LG; Juranyi, Z; Levay, G; Marko, B; Sziray, N | 1 |
| Ogawa, N; Tanaka, K | 1 |
| Bohn, MC; Kozlowski, DA; Smith, AD; Zigmond, MJ | 1 |
| Asanuma, M; Diaz-Corrales, FJ; Miyazaki, I; Ogawa, N; Shimizu, M; Tanaka, K | 1 |
| Ahmad, AS; Ahmad, M; Ansari, MA; Hoda, MN; Islam, F; Saleem, S; Yousuf, S | 1 |
| Higashio, C; Kabuto, H; Kohno, M; Nishizawa, M; Shishibori, T; Tada, M | 1 |
| Datla, KP; Dexter, DT; Zbarsky, V | 1 |
| Aruoma, OI; Datla, KP; Dexter, DT; Parkar, S; Rai, DK; Zbarsky, V | 1 |
| Dowd, E; Fitzsimmons, DF; Moloney, TC | 1 |
| Bezard, E; Bioulac, B; Boraud, T; Gross, CE; Harnack, D; Klitgaard, H; Kupsch, A; Meissner, W; Morgenstern, R; Ravenscroft, P; Reese, R | 1 |
| Cannon, JR; Hua, Y; Keep, RF; Richardson, RJ; Schallert, T; Xi, G | 1 |
| Croucher, MJ; Datla, KP; Dexter, DT; Vernon, AC; Zbarsky, V | 1 |
| Gacsalyi, I; Harsing, LG; Juranyi, Z; Levay, G; Marko, B; Megyeri, K; Sziray, N | 1 |
| Daniel, WA; Gołembiowska, K; Wójcikowski, J | 1 |
| Bertrand, A; Boulet, S; Carcenac, C; Feuerstein, C; Lacombe, E; Poupard, A; Savasta, M | 1 |
| Barbanoj, M; Kulisevsky, J; Pérez, V; Rodríguez-Alvarez, J; Rubio, A; Sosti, V | 1 |
| Buck, K; Ferger, B | 1 |
| Chen, H; Jing, FC; Li, CL; Tu, PF; Wang, ZH; Zheng, QS | 1 |
| Achaval, M; Anselmo-Franci, JA; Delattre, AM; Ferraz, AC; Hermel, Edo E; Matheussi, F; Rigon, P; Rizelio, V; Szawka, RE; Xavier, LL | 1 |
| Adkins, DL; Allred, RP; Husbands, LC; Jones, TA; Kane, JR; Maldonado, MA; Schallert, T; Woodlee, MT | 1 |
| Antonelli, T; Cassano, T; Cuomo, V; Dipasquale, P; Ferraro, L; Gaetani, S; Giuffrida, A; Laconca, L; Macheda, T; Morgese, MG | 1 |
| Amakawa, M; Kabuto, H; Mankura, M; Mori, A; Yamanushi, TT | 1 |
| An, L; Cheng, B; Gao, B; Liu, S; Liu, X; Yang, X | 1 |
| Chen, YC; Chiang, YH; Chiu, PL; Chiu, WT; Hung, KS; Lin, CM; Lin, JW; Shih, CM; Shih, R; Tsai, JT; Wei, L; Yang, LY; Yeh, YS | 1 |
| Dong, WL; Kong, Y; Xue, SR; Yang, XX | 1 |
| Bertrand, A; Dentresangle, C; Detraz, I; Dzahini, K; Le Cavorsin, M; Leviel, V; Savasta, M | 1 |
| Agnati, LF; Aguirre, JA; Fuxe, K; Hagman, B; Kehr, J; Marcellino, D; Rivera, A; Sánchez-Reina, MD; Suárez-Boomgaard, D; Yoshitake, S; Yoshitake, T | 1 |
| Borah, A; Mohanakumar, KP | 1 |
| Cass, WA; Peters, LE | 1 |
| Chao, OY; Huston, JP; Pum, ME; von Bothmer, A | 1 |
| Chao, OY; Huston, JP; Mattern, C; Nikolaus, S; Pum, ME; Ruocco, LA; Silva, AM; Wessler, J | 1 |
| Lin, L; Liu, TT; Meng, T; Zheng, ZH | 1 |
| Breyer, MD; Breyer, RM; Deguchi, Y; Furuyashiki, T; Imoto, Y; Kitaoka, S; Narumiya, S; Segi-Nishida, E; Senzai, Y; Tanaka, K | 1 |
| Lin, L; Liu, T; Meng, T; Zheng, Z | 1 |
| Huston, JP; Petri, D; Pum, M; Schnitzler, A; Vesper, J | 1 |
| Gao, Y; Han, B; Hu, J; Lu, Y; Shen, J; Wang, T | 1 |
| Kuwabara, S; Sakakibara, R; Taniguchi, J; Uchiyama, T; Yamamoto, T | 1 |
| Brus, R; Kostrzewa, RM; Malinowska-Borowska, J; Nowak, D; Nowak, P; Szkilnik, R; Waliczek, M | 1 |
| Han, B; Jin, HJ; Song, MY; Wang, T; Zhao, H | 1 |
| Bähr, M; Koch, JC; Lingor, P; Michel, U; Ribas, VT; Saal, KA; Szegő, EM; Tatenhorst, L; Tönges, L | 1 |
| Czarnecka, A; Kamińska, K; Konieczny, J; Lenda, T; Nowak, P | 1 |
| Bouchard, RS; Gittis, AH; Willard, AM | 1 |
| Antunes, MS; Boeira, SP; Goes, ATR; Jesse, CR; Lobo Ladd, AAB; Lobo Ladd, FV; Luchese, C; Paroul, N | 1 |
| Bähr, M; Cheng, S; Déglon, N; Konstantinova, P; Kügler, S; Liefhebber, J; Mazur, A; Pythoud, C; Raina, A; Rey, M; Streit, F; Tereshchenko, J; Vachey, G; Zimmer, V | 1 |
| Boeira, SP; Cattelan Souza, L; de Gomes, MG; Del Fabbro, L; Furian, AF; Jesse, CR; Lobo Ladd, AAB; Lobo Ladd, FV; Nunes Arantes, RV; Oliveira, MS; Reis Simionato, A; Rossito Goes, A | 1 |
1 review(s) available for homovanillic acid and oxidopamine
| Article | Year |
|---|---|
Inhibitory mechanisms in the substantia nigra and the dopamine pathway.
Topics: Amino Acids; Amino Acids, Cyclic; Animals; Brain Mapping; Cats; Corpus Striatum; Cyclohexanecarboxylic Acids; Dopamine; Electrophysiology; Ethanolamines; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Homovanillic Acid; Hydroxydopamines; Mice; Motor Activity; Muscimol; Neural Inhibition; Neural Pathways; Oxidopamine; Picrotoxin; Rats; Substantia Nigra | 1979 |
171 other study(ies) available for homovanillic acid and oxidopamine
| Article | Year |
|---|---|
Dissociation of the striatal D-2 dopamine receptor from adenylyl cyclase following 6-hydroxydopamine-induced denervation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Benzazepines; Corpus Striatum; Cyclic AMP; Denervation; Dopamine; Ergolines; Female; Homovanillic Acid; Oxidopamine; Prosencephalon; Quinpirole; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone | 1992 |
Behavioral effects of concurrent lesions of the nucleus basalis magnocellularis and the dorsal noradrenergic bundle.
Topics: Analysis of Variance; Animals; Biogenic Monoamines; Cerebral Cortex; Choline O-Acetyltransferase; Dopamine; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Ibotenic Acid; Male; Memory; Methoxyhydroxyphenylglycol; Motor Activity; Norepinephrine; Oxidopamine; Rats; Rats, Inbred F344; Serotonin; Vestibular Nuclei | 1992 |
Slow changes of tyrosine hydroxylase gene expression in dopaminergic brain neurons after neurotoxin lesioning: a model for neuron aging.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amino Acid Sequence; Animals; Biogenic Monoamines; Corpus Striatum; Dopamine; Gene Expression Regulation, Enzymologic; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Immunohistochemistry; Male; Molecular Sequence Data; Neurons; Norepinephrine; Nucleic Acid Hybridization; Oxidopamine; Rats; Rats, Inbred F344; RNA, Messenger; Sequence Homology, Nucleic Acid; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase | 1992 |
Selective subregional dopamine depletions in the rat caudate-putamen following nigrostriatal lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Nerve Degeneration; Oxidopamine; Putamen; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra; Sympathectomy, Chemical | 1992 |
Recovery from unilateral 6-hydroxydopamine lesion of substantia nigra promoted by the neurotachykinin substance P 1-11.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Dopamine; Homovanillic Acid; Male; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra; Sympathectomy, Chemical; Tachykinins | 1992 |
Do forebrain structures compete for behavioral expression? Evidence from amphetamine-induced behavior, microdialysis, and caudate-accumbens lesions in medial frontal cortex damaged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Analysis of Variance; Animals; Biogenic Monoamines; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Prosencephalon; Rats; Stereotaxic Techniques; Stereotyped Behavior; Time Factors | 1992 |
Biotransformation of L-dopa in striatum and substantia nigra of rats with a unilateral, nigrostriatal lesion: a microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Anesthetics; Animals; Biotransformation; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; Homovanillic Acid; Levodopa; Male; Oxidopamine; Rats; Rats, Wistar; Substantia Nigra | 1992 |
Induction of D2 dopamine receptor mRNA synthesis in a 6-hydroxydopamine parkinsonian rat model.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Blotting, Northern; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Neurons, Efferent; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; RNA, Messenger; Spiperone; Stereotyped Behavior; Substantia Nigra | 1992 |
Changes in striatal dopamine neurotransmission assessed with microdialysis following recovery from a bilateral 6-OHDA lesion: variation as a function of lesion size.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Brain Diseases; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Osmolar Concentration; Oxidopamine; Rats; Synaptic Transmission | 1990 |
Serotonergic sprouting is induced by dopamine-lesion in substantia nigra of adult rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Functional Laterality; Globus Pallidus; Homovanillic Acid; Hydroxyindoleacetic Acid; Nerve Fibers; Nerve Regeneration; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase | 1991 |
Cholinergic stimulation of substantia nigra: abolition of carbachol-induced eating by unilateral 6-hydroxydopamine lesion of nigrostriatal dopamine neurones.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Mapping; Carbachol; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Feeding Behavior; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Microinjections; Oxidopamine; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Stereotaxic Techniques; Substantia Nigra | 1991 |
Influence of oxygen availability on the neurotoxic effect of 6-hydroxydopamine on nigro-striatal dopaminergic neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atmospheric Pressure; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Homovanillic Acid; In Vitro Techniques; Injections, Intraventricular; Male; Membrane Proteins; Mice; Nerve Tissue Proteins; Nervous System Diseases; Neurons; Oxidopamine; Oxygen; Substantia Nigra; Synaptosomes | 1991 |
Decrease of behavioral and biochemical denervation supersensitivity of rat striatum by nigral transplants.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Brain Tissue Transplantation; Corpus Striatum; Denervation; Dopamine; Ergolines; Fetal Tissue Transplantation; Homovanillic Acid; Indoles; Mesencephalon; Motor Activity; Oxidopamine; Phenanthridines; Quinpirole; Rats; Receptors, Dopamine; Substantia Nigra | 1991 |
Chronic L-dopa treatment in the unilateral 6-OHDA rat: evidence for behavioral sensitization and biochemical tolerance.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Carbidopa; Corpus Striatum; Denervation; Drug Tolerance; Functional Laterality; Homovanillic Acid; Levodopa; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1991 |
The iron chelator desferrioxamine (Desferal) retards 6-hydroxydopamine-induced degeneration of nigrostriatal dopamine neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Deferoxamine; Dopamine; Homovanillic Acid; Hydroxydopamines; Iron Chelating Agents; Male; Nerve Degeneration; Neurons; Neurotoxins; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1991 |
Antiparkinson-like effects of neurotensin in 6-hydroxydopamine lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Behavior, Animal; Brain Chemistry; Catalepsy; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxydopamines; Hypothalamus; Injections, Intraventricular; Male; Neurotensin; Norepinephrine; Oxidopamine; Parkinson Disease, Secondary; Rats; Sympathectomy, Chemical | 1991 |
Hypokinesia, rigidity, and tremor induced by hypothalamic 6-OHDA lesions in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Dyskinesia, Drug-Induced; Homovanillic Acid; Humans; Hydroxydopamines; Hypothalamus, Posterior; Male; Muscle Rigidity; Oxidopamine; Parkinson Disease; Rats; Tremor | 1991 |
Effect of intra-amygdala dopaminergic grafts on methamphetamine-induced locomotor activity, extracellular dopamine and dopamine metabolite overflow: a comparison with the effect of intra-accumbens grafts.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amygdala; Animals; Brain Tissue Transplantation; Dopamine; Electrophysiology; Homovanillic Acid; Hydroxydopamines; Male; Methamphetamine; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains | 1991 |
Striatal L-dopa metabolism studied in vivo in rats with nigrostriatal lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Levodopa; Male; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1990 |
Environmental stress increases extracellular dopamine in striatum of 6-hydroxydopamine-treated rats: in vivo microdialysis studies.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Ventricles; Corpus Striatum; Dopamine; Electroshock; Extracellular Space; Homovanillic Acid; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains; Reference Values; Stress, Psychological | 1990 |
Differential regulation of dopamine metabolism in solid fetal substantia nigra transplants and their terminals in the host striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Brain Tissue Transplantation; Corpus Striatum; Dopamine; Feedback; Fetal Tissue Transplantation; Homovanillic Acid; Hydroxydopamines; Male; Nerve Endings; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra | 1990 |
In vivo studies of striatal dopamine release and metabolism following administration of L-dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Levodopa; Male; Neural Pathways; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Synaptic Transmission | 1990 |
Dopamine metabolites in rat cisternal cerebrospinal fluid: major contribution from extrastriatal dopamine neurones.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzylamines; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Dopamine; Hippocampus; Homovanillic Acid; Humans; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Neurons; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Serotonin | 1986 |
The neurotoxic actions of 6-hydroxydopamine infused into the rat substantia nigra.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Movement Disorders; Neurotransmitter Agents; Oxidopamine; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Substantia Nigra | 1986 |
Selective depletion of cerebral norepinephrine with 6-hydroxydopamine and GBR-12909 in neonatal rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain Chemistry; Dopamine; Female; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Norepinephrine; Oxidopamine; Piperazines; Rats; Rats, Inbred Strains; Serotonin | 1986 |
Biochemical and radioautographic evidence for dopaminergic afferents of the locus coeruleus originating in the ventral tegmental area.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Dopamine; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Locus Coeruleus; Male; Neural Pathways; Neurons, Afferent; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Septal Nuclei; Serotonin; Tegmentum Mesencephali | 1987 |
A two-population model of rat rotational behavior: effects of unilateral nigrostriatal 6-hydroxydopamine on striatal neurochemistry and amphetamine-induced rotation.
Topics: Animals; Biogenic Amines; Corpus Striatum; Dextroamphetamine; Dopamine; Female; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Models, Neurological; Oxidopamine; Rats; Rats, Inbred Strains; Rotation; Serotonin; Stereotyped Behavior; Substantia Nigra | 1987 |
Striatal adenosine levels measured 'in vivo' by microdialysis in rats with unilateral dopamine denervation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Denervation; Dialysis; Dopamine; Guanosine; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Hypoxanthine; Hypoxanthines; Inosine; Male; Oxidopamine; Rats; Rats, Inbred Strains | 1987 |
Intraventricular microdialysis: a new method for determining monoamine metabolite concentrations in the cerebrospinal fluid of freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Medulla; Animals; Cerebral Ventricles; Dialysis; Dopamine; Female; Haloperidol; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Oxidopamine; Phenylacetates; Probenecid; Rats; Substantia Nigra | 1988 |
Vitamin E attenuates the toxic effects of intrastriatal injection of 6-hydroxydopamine (6-OHDA) in rats: behavioral and biochemical evidence.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Drug Interactions; Homovanillic Acid; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains; Stereotyped Behavior; Vitamin E | 1989 |
Amphetamine-induced rotation reveals post 6-OHDA lesion neurochemical reorganization.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dextroamphetamine; Dominance, Cerebral; Dopamine; Homovanillic Acid; Hydroxydopamines; Limbic System; Male; Mesencephalon; Neural Pathways; Nucleus Accumbens; Olfactory Bulb; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Substantia Nigra | 1989 |
Lesion-induced reductions in trace amine accumulation: dependence on MAO inhibitor pretreatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Male; Monoamine Oxidase Inhibitors; Oxidopamine; Pargyline; Rats; Rats, Inbred Strains; Selegiline; Substantia Nigra; Tryptamines | 1989 |
Preservation of dopamine release in the denervated striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1989 |
Mesolimbic dopamine and early post-6-OHDA lesion enhanced responses to d-amphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dextroamphetamine; Dopamine; Homovanillic Acid; Hydroxydopamines; Limbic System; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains | 1989 |
Regional distribution of calcium/calmodulin-dependent phosphatase activity of calcineurin in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Calcineurin; Calcium; Calmodulin; Calmodulin-Binding Proteins; Corpus Striatum; Dopamine; Glutamate Decarboxylase; Homovanillic Acid; Hydroxydopamines; Kainic Acid; Male; Oxidopamine; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Substantia Nigra; Sympathectomy, Chemical | 1989 |
Effects of intraventricular injections of 6-hydroxydopamine on amine metabolites in rat brain and urine.
Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Adrenal Glands; Animals; Biogenic Amines; Brain Chemistry; Dopamine; Ethylene Glycols; Gas Chromatography-Mass Spectrometry; Heart; Homovanillic Acid; Hydroxydopamines; Injections, Intraventricular; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Organ Size; Oxidopamine; Phenols; Phenylethyl Alcohol; Rats; Rats, Inbred Strains; Spleen | 1985 |
Partial lesions of the nigrostriatal pathway in the rat. Acceleration of transmitter synthesis and release of surviving dopaminergic neurones by drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Homovanillic Acid; Hydroxydopamines; Male; Morphine; Neurons; Neurotransmitter Agents; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1985 |
Effect of ischemia on the in vivo release of striatal dopamine, glutamate, and gamma-aminobutyric acid studied by intracerebral microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebrovascular Circulation; Corpus Striatum; Denervation; Dialysis; Dopamine; Energy Metabolism; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Homovanillic Acid; Hydroxydopamines; Ischemic Attack, Transient; Kinetics; Male; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1988 |
Repeated stimulation of D-1 dopamine receptors increases the circling response to bromocriptine in rats with a 6-OHDA lesion.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Animals; Appetite Depressants; Benzazepines; Bromocriptine; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Hydroxydopamines; Locomotion; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra | 1988 |
Relationship of changes in spontaneous motor activity to spontaneous circling in rats with unilateral 6-hydroxydopamine lesions of the substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Limbic System; Male; Motor Activity; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1986 |
Dose related effects of 6-OHDA on rabbit retinal dopamine concentrations and ERG B-wave amplitudes.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Dose-Response Relationship, Drug; Electroretinography; Homovanillic Acid; Hydroxydopamines; Microinjections; Oxidopamine; Rabbits; Retina; Vitreous Body | 1986 |
The role of dopamine in intracranial self-stimulation of the ventral tegmental area.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Corpus Striatum; Dopamine; Electric Stimulation; Homovanillic Acid; Hydroxydopamines; Male; Nucleus Accumbens; Olfactory Bulb; Oxidopamine; Rats; Reinforcement, Psychology; Tegmentum Mesencephali | 1987 |
A central 6-hydroxydopamine lesion prevents fluphenazine-induced increase in plasma homovanillic acid.
Topics: Animals; Brain; Corpus Striatum; Dopamine; Fluphenazine; Frontal Lobe; Homovanillic Acid; Hydroxydopamines; Injections, Intraperitoneal; Injections, Intraventricular; Male; Oxidopamine; Rats; Rats, Inbred Strains; Time Factors | 1988 |
Normalization of extracellular dopamine in striatum following recovery from a partial unilateral 6-OHDA lesion of the substantia nigra: a microdialysis study in freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Hydroxydopamines; Oxidopamine; Rats; Stereotyped Behavior; Substantia Nigra | 1988 |
Two kinds of nigrostriatal asymmetry: relationship to dopaminergic drug sensitivity and 6-hydroxydopamine lesion effects in Long-Evans rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Apomorphine; Corpus Striatum; Dopamine; Female; Functional Laterality; Homovanillic Acid; Hydroxydopamines; Male; Oxidopamine; Pergolide; Rats; Species Specificity; Substantia Nigra | 1988 |
Increased dopamine release from striata of rats after unilateral nigrostriatal bundle damage.
Topics: 4-Butyrolactone; Animals; Corpus Striatum; Dopamine; Furans; Haloperidol; Homovanillic Acid; Hydroxydopamines; Male; Oxidopamine; Potassium Chloride; Rats; Rats, Inbred F344; Substantia Nigra | 1988 |
The response of apomorphine administered into the accumbens in rats with bilateral lesions of the nucleus accumbens, induced with 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Dopamine; Homovanillic Acid; Hydroxydopamines; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Septal Nuclei | 1988 |
Detection of homovanillic acid in vivo using microcomputer-controlled voltammetry: simultaneous monitoring of rat motor activity and striatal dopamine release.
Topics: 4-Butyrolactone; alpha-Methyltyrosine; Animals; Computers; Corpus Striatum; Dopamine; Electrochemistry; Homovanillic Acid; Hydroxydopamines; Male; Methyltyrosines; Motor Activity; Neural Pathways; Oxidopamine; Phenylacetates; Rats; Rats, Inbred Strains; Substantia Nigra | 1985 |
Effect of chronic apomorphine on the development of denervation supersensitivity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Corpus Striatum; Denervation; Desipramine; Dopamine; Homovanillic Acid; Hydroxydopamines; Injections; Male; Medial Forebrain Bundle; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1985 |
Dopamine sulfoconjugation in the rat brain: regulation by monoamine oxidase.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Brain Stem; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxydopamines; Hypothalamus; Male; Monoamine Oxidase; Oxidopamine; Pargyline; Rats; Rats, Inbred Strains | 1985 |
Compensatory mechanisms in the nigrostriatal dopaminergic system in Parkinson's disease: studies in an animal model.
Topics: Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Male; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Tyrosine 3-Monooxygenase | 1982 |
Spontaneous recovery from motor asymmetry in adult rats with 6-hydroxydopamine-induced partial lesions of the substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Dopamine; Female; Functional Laterality; Homovanillic Acid; Hydroxydopamines; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra; Tyrosine 3-Monooxygenase | 1984 |
In vivo dopamine receptor binding studies with a non-radioactively labeled agonist, dipropyl-5,6-ADTN.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebellum; Corpus Striatum; Domperidone; Female; Homovanillic Acid; Hydroxydopamines; Male; Methysergide; Naphthalenes; Occipital Lobe; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sympatholytics; Tetrahydronaphthalenes; Tranquilizing Agents | 1983 |
In vivo binding of N-n-propylnorapomorphine in the rat brain: regional localization, quantification in striatum and lack of correlation with dopamine metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Binding Sites; Brain; Chemical Phenomena; Chemistry; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Behavioral and neurochemical effects of neurotensin microinjection into the ventral tegmental area of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Haloperidol; Homovanillic Acid; Hydroxydopamines; Male; Microinjections; Motor Activity; Neurotensin; Nucleus Accumbens; Olfactory Bulb; Oxidopamine; Rats; Rats, Inbred Strains; Tegmentum Mesencephali | 1983 |
Sensorimotor impairment and elevated levels of dopamine metabolites in the neostriatum occur rapidly after intranigral injection of 6-hydroxydopamine or gamma-hydroxybutyrate in awake rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Biotransformation; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxybutyrates; Hydroxydopamines; Male; Microinjections; Oxidopamine; Procaine; Psychomotor Performance; Rats; Rats, Inbred Strains; Sodium Oxybate; Substantia Nigra | 1984 |
6-Hydroxydopamine lesions of dopaminergic A10 neurons. Long-term effects on the urinary excretion of free and conjugated catecholamines and their metabolites in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Dopamine; Homovanillic Acid; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains; Tegmentum Mesencephali | 1982 |
Selective lesions by manganese and extensive damage by iron after injection into rat striatum or hippocampus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Basal Ganglia; Biogenic Amines; Calcium; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Functional Laterality; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Iron; Kinetics; Male; Manganese; Manganese Poisoning; Neurotoxins; Norepinephrine; Oxidopamine; Rats; Rats, Wistar; Serotonin; Time Factors | 1994 |
Time course of recovery of extracellular dopamine following partial damage to the nigrostriatal dopamine system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Extracellular Space; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Kinetics; Microdialysis; Oxidopamine; Rats; Rats, Sprague-Dawley; Reference Values; Substantia Nigra; Time Factors | 1994 |
Efficacy of brain-derived neurotrophic factor and neurotrophin-3 on neurochemical and behavioral deficits associated with partial nigrostriatal dopamine lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Nerve Growth Factors; Nerve Tissue Proteins; Neurotrophin 3; Oxidopamine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Serotonin; Substantia Nigra | 1994 |
Effects of selective dopamine depletion in medial prefrontal cortex on basal and evoked extracellular dopamine in neostriatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Basal Metabolism; Dopamine; Fluorescent Dyes; Homovanillic Acid; Male; Microdialysis; Neostriatum; Nerve Endings; Neurons; Oxidopamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stilbamidines | 1995 |
Complex deficits on reaction time performance following bilateral intrastriatal 6-OHDA infusion in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Frontal Lobe; Homovanillic Acid; Immunohistochemistry; Male; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Reaction Time; Task Performance and Analysis | 1995 |
Influence of selective inhibition of monoamine oxidase A or B on striatal metabolism of L-DOPA in hemiparkinsonian rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clorgyline; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Indans; Levodopa; Male; Monoamine Oxidase Inhibitors; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Selegiline; Substantia Nigra | 1995 |
Reversal of 6HD-induced neonatal brain catecholamine depletion after operant training.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain Chemistry; Catecholamines; Cerebral Cortex; Conditioning, Operant; Dopamine; Homovanillic Acid; Male; Neostriatum; Neuronal Plasticity; Oxidopamine; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Sympathectomy, Chemical | 1995 |
Behavioral indices of moderate nigro-striatal 6-hydroxydopamine lesion: a preclinical Parkinson's model.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Corpus Striatum; Dopamine; Functional Laterality; Homovanillic Acid; Hydroxyindoleacetic Acid; Locomotion; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Serotonin; Substantia Nigra | 1993 |
In vivo electrochemical measurements and electrophysiological studies of rat striatum following neonatal 6-hydroxydopamine treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Ascorbic Acid; Corpus Striatum; Dopamine; Electrochemistry; Electrophysiology; Functional Laterality; Glutamates; Glutamic Acid; Homovanillic Acid; Hydroxyindoleacetic Acid; Kinetics; Male; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin; Time Factors | 1993 |
Differential cholinergic and non-cholinergic actions of acetylcholinesterase in the substantia nigra revealed by fasciculin-induced inhibition.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholinesterase; Animals; Apomorphine; Biogenic Amines; Cell Membrane; Cholinesterase Inhibitors; Dopamine; Elapid Venoms; Functional Laterality; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Rotation; Serotonin; Substantia Nigra | 1993 |
Effect of repeated electroconvulsive shock on striatal L-dopa and dopamine metabolism: an in vivo study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Corpus Striatum; Dopamine; Electroshock; Extracellular Space; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Microdialysis; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1993 |
Cerebrospinal dopamine metabolites in rats after intrastriatal administration of 6-hydroxydopamine or 1-methyl-4-phenylpyridinium ion.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Male; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley | 1995 |
'Priming' enhances the relationship of striatal L-dopa concentration to behavior.
Topics: Animals; Behavior, Animal; Brain Chemistry; Dopamine; Homovanillic Acid; Levodopa; Male; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques | 1994 |
Fluoxetine at anorectic doses does not have properties of a dopamine uptake inhibitor.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Appetite Depressants; Brain Chemistry; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; Homovanillic Acid; Injections, Intraventricular; Male; Mazindol; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley | 1994 |
On the origin of striatal cholecystokinin release: studies with in vivo microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Afferent Pathways; Animals; Aspartic Acid; Calcium; Cholecystokinin; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Homovanillic Acid; Male; Microdialysis; Oxidopamine; Potassium; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Sincalide | 1994 |
Estradiol increases tyrosine hydroxylase activity of the A15 nucleus dopaminergic neurons during long days in the ewe.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Dialysis; Dopamine; Estradiol; Female; Homovanillic Acid; Hypothalamus; Levodopa; Luteinizing Hormone; Neurons; Nomifensine; Norepinephrine; Ovariectomy; Oxidopamine; Photoperiod; Sheep; Tyrosine 3-Monooxygenase | 1994 |
Biotransformation of locally applied L-dopa in the corpus striatum of the hemi-parkinsonian rat studied with microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Biotransformation; Corpus Striatum; Denervation; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Homovanillic Acid; Levodopa; Male; Microdialysis; Nomifensine; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Tetrodotoxin | 1994 |
6-Hydroxydopamine lesions of the medial prefrontal cortex of rats do not affect dopamine metabolism in the basal ganglia at short and long postsurgical intervals.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Basal Ganglia; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Nucleus Accumbens; Oxidopamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Differential effects of chronic L-dopa treatment on lipid peroxidation in the mouse brain with or without pretreatment with 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Homovanillic Acid; Levodopa; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Neurons; Oxidopamine; Thiobarbituric Acid Reactive Substances | 1994 |
6-OHDA-treated weanling rats show normal neuroleptic sensitivity as adults on LHSS.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Electrodes, Implanted; Homovanillic Acid; Hypothalamic Area, Lateral; Injections, Intraventricular; Male; Motor Activity; Oxidopamine; Pimozide; Rats; Rats, Sprague-Dawley; Reward; Self Stimulation; Sympathectomy, Chemical | 1993 |
Effect of M1- and M2-muscarinic drugs on striatal dopamine release and metabolism: an in vivo microdialysis study comparing normal and 6-hydroxydopamine-lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atropine; Carbachol; Corpus Striatum; Diamines; Dopamine; Homovanillic Acid; Male; Microdialysis; Oxidopamine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Reference Values | 1993 |
Dopaminergic functional supersensitivity: effects of chronic L-dopa and carbidopa treatment in an animal model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biopterins; Brain Diseases; Carbidopa; Corpus Striatum; Cyclic AMP; Disease Models, Animal; Dopamine; Dopamine D2 Receptor Antagonists; Homovanillic Acid; Levodopa; Male; Oxidopamine; Parkinson Disease; Rats; Rats, Inbred F344; Receptors, Dopamine D1; Receptors, Dopamine D2; Sensitivity and Specificity; Substantia Nigra; Time Factors | 1993 |
The role of nucleus accumbens dopamine in the neurochemical and behavioral effects of phencyclidine: a microdialysis and behavioral study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Ataxia; Behavior, Animal; Brain Chemistry; Chromatography, High Pressure Liquid; Dialysis; Dopamine; Homovanillic Acid; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Phencyclidine; Rats; Rats, Sprague-Dawley; Social Behavior; Stereotyped Behavior; Sympathectomy, Chemical | 1993 |
Involvement of D2 dopaminergic receptors in the emotional and motivational responses induced by injection of CCK-8 in the posterior part of the rat nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Emotions; Exploratory Behavior; Homovanillic Acid; Injections; Male; Motivation; Nucleus Accumbens; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine D2; Sincalide; Tegmentum Mesencephali | 1993 |
A neurochemical and behavioral investigation of the involvement of nucleus accumbens dopamine in instrumental avoidance.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Avoidance Learning; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Dopamine; Electroshock; Frontal Lobe; Homovanillic Acid; Male; Nucleus Accumbens; Oxidopamine; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Chronic effects of single intrastriatal injections of 6-hydroxydopamine or 1-methyl-4-phenylpyridinium studied by microdialysis in freely moving rats.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Dopamine Agents; Extracellular Space; Homovanillic Acid; Immunohistochemistry; Injections; Male; Microdialysis; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra; Sympatholytics | 1995 |
Modulation of neurotransmitter release by cholecystokinin in the neostriatum and substantia nigra of the rat: regional and receptor specificity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Cholecystokinin; Dopamine; Dynorphins; Endorphins; gamma-Aminobutyric Acid; Glutamic Acid; Homovanillic Acid; Kinetics; Male; Neostriatum; Neurons; Neurotransmitter Agents; Organ Specificity; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Substantia Nigra; Time Factors | 1996 |
Cyclosporin A attenuates degeneration of dopaminergic neurons induced by 6-hydroxydopamine in the mouse brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cell Death; Cyclosporine; Dopamine; Homovanillic Acid; Immunosuppressive Agents; Male; Mice; Mice, Inbred ICR; Neostriatum; Neurons; Neuroprotective Agents; Oxidopamine; Substantia Nigra | 1996 |
Differential sensitivity of dopamine release and clearance to 6-hydroxydopamine lesioning in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Electrodes, Implanted; Homovanillic Acid; Nomifensine; Oxidopamine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sympatholytics | 1996 |
Dynamic regulation of striatal dopaminergic grafts during locomotor activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cell Transplantation; Corpus Striatum; Dopamine; Extracellular Space; Homovanillic Acid; Methamphetamine; Microdialysis; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Rotation; Stereotyped Behavior; Substantia Nigra; Time Factors | 1996 |
Behavioral and neurochemical recovery from partial 6-hydroxydopamine lesions of the substantia nigra is blocked by daily treatment with D1/D5, but not D2, dopamine receptor antagonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Benzazepines; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Homovanillic Acid; Male; Microdialysis; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D5; Substantia Nigra; Sympatholytics | 1997 |
Cyclosporin A attenuates the decrease in tyrosine hydroxylase immunoreactivity in nigrostriatal dopaminergic neurons and in striatal dopamine content in rats with intrastriatal injection of 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Cyclosporine; Dopamine; Homovanillic Acid; Immunosuppressive Agents; Injections; Male; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase | 1997 |
Growth/differentiation factor 5 protects nigrostriatal dopaminergic neurones in a rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Bone Morphogenetic Proteins; Corpus Striatum; Dopamine; Growth Differentiation Factor 5; Growth Substances; Homovanillic Acid; Injections, Intraventricular; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Rats; Recombinant Proteins; Substantia Nigra; Transforming Growth Factor beta | 1997 |
Lesion of nigrostriatal neurons by 6-hydroxydopamine induces changes in rat brain glutathione-S-transferase.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Enzyme Induction; Glutathione Transferase; Homovanillic Acid; Male; Neurons; Neurotoxins; Oxidopamine; Rats; Rats, Wistar; Substantia Nigra | 1997 |
Distribution of zinc in the substantia nigra of rats treated with 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Autoradiography; Blood-Brain Barrier; Chlorides; Corpus Striatum; Gliosis; Homovanillic Acid; In Vitro Techniques; Injections, Intravenous; Male; Nerve Degeneration; Oxidopamine; Quaternary Ammonium Compounds; Radionuclide Imaging; Rats; Rats, Wistar; Substantia Nigra; Technetium Compounds; Time Factors; Zinc; Zinc Compounds; Zinc Radioisotopes | 1998 |
Dopamine metabolism in the striatum of hemiparkinsonian model rats with dopaminergic grafts.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Brain Tissue Transplantation; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Fetal Tissue Transplantation; Functional Laterality; Haloperidol; Homovanillic Acid; Kinetics; Levodopa; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Methamphetamine; Microdialysis; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Rotation; Tritium; Tyrosine 3-Monooxygenase | 1998 |
Progressive accumbens degeneration after neonatal striatal 6-hydroxydopamine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Caudate Nucleus; Chromatography, High Pressure Liquid; Disease Progression; Dopamine; Homovanillic Acid; Nerve Degeneration; Neurotoxins; Nucleus Accumbens; Oxidopamine; Parkinson Disease, Secondary; Putamen; Rats; Rats, Sprague-Dawley | 1998 |
Effect of trihexyphenidyl, a non-selective antimuscarinic drug, on decarboxylation of L-dopa in hemi-Parkinson rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Biotransformation; Corpus Striatum; Decarboxylation; Dopamine; Drug Interactions; Homovanillic Acid; Levodopa; Male; Microdialysis; Muscarinic Antagonists; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Substantia Nigra; Trihexyphenidyl | 1998 |
Long-term protection of the rat nigrostriatal dopaminergic system by glial cell line-derived neurotrophic factor against 6-hydroxydopamine in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Corpus Striatum; Dopamine; Glial Cell Line-Derived Neurotrophic Factor; Homovanillic Acid; Male; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra; Sympatholytics; Time Factors; Tomography, Emission-Computed; Tyrosine 3-Monooxygenase | 1998 |
Catecholaminergic mechanisms-mediated hypothermia induced by magnolol in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; alpha-Methyltyrosine; Animals; Anti-Anxiety Agents; Biphenyl Compounds; Body Temperature; Catecholamines; Colon; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epinephrine; Homovanillic Acid; Hypothalamus; Hypothermia, Induced; Injections, Intraperitoneal; Injections, Intraventricular; Levodopa; Lignans; Male; Norepinephrine; Oxidopamine; Rats; Rats, Sprague-Dawley | 1998 |
Pergolide potentiates L-DOPA-induced dopamine release in rat striatum after lesioning with 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Disease Models, Animal; Dopamine; Dopamine Agonists; Drug Synergism; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Microdialysis; Motor Activity; Neostriatum; Neurons; Oxidopamine; Parkinson Disease, Secondary; Pergolide; Rats; Rats, Wistar | 1999 |
Dopamine depletion in the medial prefrontal cortex induces sensitized-like behavioral and neurochemical responses to cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain Chemistry; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Tolerance; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Microdialysis; Nucleus Accumbens; Oxidopamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sympatholytics; Synaptic Transmission | 1999 |
Effects of partial dopamine loss in the medial prefrontal cortex on local baseline and stress-evoked extracellular dopamine concentrations.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Axons; Dopamine; Dopamine beta-Hydroxylase; Extracellular Space; Homovanillic Acid; Immunohistochemistry; Male; Microdialysis; Oxidopamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stress, Psychological; Sympatholytics; Tyrosine 3-Monooxygenase | 1999 |
EPC-K1, a hydroxyl radical scavenger, prevents 6-hydroxydopamine-induced dopamine depletion in the mouse striatum by up-regulation of catalase activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Ascorbic Acid; Catalase; Cerebral Ventricles; Corpus Striatum; Dopamine; Free Radical Scavengers; Glutathione; Homovanillic Acid; Hydroxyl Radical; Injections, Intraventricular; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Oxidopamine; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vitamin E | 1999 |
The effect of a subchronic post-lesion treatment with (-)-deprenyl on the sensitivity of 6-OHDA-lesioned rats to apomorphine and d-amphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; Male; Medial Forebrain Bundle; Oxidopamine; Rats; Rats, Sprague-Dawley; Selegiline | 1999 |
Reserpine pretreatment prevents increases in extracellular striatal dopamine following L-DOPA administration in rats with nigrostriatal denervation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Denervation; Dopamine; Extracellular Space; Homovanillic Acid; Levodopa; Male; Oxidopamine; Rats; Rats, Wistar; Reserpine; Substantia Nigra | 2000 |
Striatal trophic activity is reduced in the aged rat brain.
Topics: Aging; Animals; Brain; Cells, Cultured; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Embryo, Mammalian; Functional Laterality; Homovanillic Acid; Mesencephalon; Neurons; Oxidopamine; Rats; Rats, Inbred F344; Tissue Extracts | 2000 |
Estimation of striatal dopamine spillover and metabolism in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Injections; Male; Medial Forebrain Bundle; Microdialysis; Osmolar Concentration; Oxidopamine; Rats; Rats, Sprague-Dawley; Sucrose | 2000 |
The influence of pallidal deep brain stimulation on striatal dopaminergic metabolism in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Denervation; Dopamine; Electric Stimulation Therapy; Globus Pallidus; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Neostriatum; Neural Pathways; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar | 2000 |
The central aromatic amino acid DOPA decarboxylase inhibitor, NSD-1015, does not inhibit L-DOPA-induced circling in unilateral 6-OHDA-lesioned-rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Biogenic Monoamines; Brain; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Dopamine Antagonists; Drug Combinations; Enzyme Inhibitors; Haloperidol; Homovanillic Acid; Hydrazines; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Rats; Rats, Wistar; Stereotyped Behavior; Tyrosine | 2001 |
Regulation of EphB1 expression by dopamine signaling.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Ephrin-B1; Female; Gene Expression; Homovanillic Acid; In Situ Hybridization; Membrane Proteins; Mice; Mice, Inbred Strains; Nerve Degeneration; Oxidopamine; Pregnancy; RNA, Messenger; Signal Transduction; Substantia Nigra; Sympatholytics | 2000 |
IGF-I and bFGF improve dopamine neuron survival and behavioral outcome in parkinsonian rats receiving cultured human fetal tissue strands.
Topics: Abortion, Induced; Animals; Apomorphine; Brain; Brain Tissue Transplantation; Cell Survival; Cells, Cultured; Disease Models, Animal; Dopamine; Female; Fetal Tissue Transplantation; Fibroblast Growth Factor 2; Homovanillic Acid; Humans; Insulin-Like Growth Factor I; Male; Methamphetamine; Motor Activity; Neurons; Oxidopamine; Parkinsonian Disorders; Pregnancy; Rats; Rats, Sprague-Dawley; Rotation; Transplantation, Heterologous; Tyrosine 3-Monooxygenase | 2001 |
Catecholamines and their metabolites in the brain and urine of rats with experimental Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Catecholamines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Homovanillic Acid; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar | 2000 |
Increased extracellular DA and normal evoked DA release in the rat striatum after a partial lesion of the substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Carrier Proteins; Caudate Nucleus; Cell Count; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Electric Stimulation; Electrodes, Implanted; Extracellular Space; Homovanillic Acid; Male; Medial Forebrain Bundle; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Oxidopamine; Putamen; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase | 2001 |
Protective effect of quinacrine on striatal dopamine levels in 6-OHDA and MPTP models of Parkinsonism in rodents.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Dopamine; Enzyme Inhibitors; Glutathione; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Parkinsonian Disorders; Phospholipases; Quinacrine; Rats; Rats, Wistar; Sympatholytics | 2001 |
Striatal dopaminergic metabolism is increased by deep brain stimulation of the subthalamic nucleus in 6-hydroxydopamine lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Electric Stimulation Therapy; Extracellular Space; Homovanillic Acid; Male; Microdialysis; Neostriatum; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Subthalamic Nucleus; Sympatholytics | 2001 |
Forced limb-use effects on the behavioral and neurochemical effects of 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Body Temperature; Casts, Surgical; Corpus Striatum; Disease Models, Animal; Dopamine; Forelimb; Homovanillic Acid; Immobilization; Male; Medial Forebrain Bundle; Membrane Glycoproteins; Membrane Transport Proteins; Microinjections; Neural Pathways; Neurons; Neuropeptides; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rats, Long-Evans; Substantia Nigra; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2001 |
Dopamine mediates striatal malonate toxicity via dopamine transporter-dependent generation of reactive oxygen species and D2 but not D1 receptor activation.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Benzazepines; Brain Diseases; Carbidopa; Carrier Proteins; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine D2 Receptor Antagonists; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Homovanillic Acid; Levodopa; Male; Malonates; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuropeptides; Oxidopamine; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Reserpine; Succinate Dehydrogenase; Sulpiride; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2001 |
Role of nitric oxide in a progressive neurodegeneration model of Parkinson's disease in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Corpus Striatum; Disease Models, Animal; Disease Progression; Dopamine; Enzyme Inhibitors; Homovanillic Acid; Male; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley | 2001 |
Melatonin reverses neurochemical alterations induced by 6-OHDA in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Free Radical Scavengers; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Male; Melatonin; Microinjections; Oxidopamine; Rats; Rats, Wistar; Serotonin; Sympatholytics | 2002 |
Forced nonuse in unilateral parkinsonian rats exacerbates injury.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Casts, Surgical; Corpus Striatum; Disease Models, Animal; Disease Progression; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Forelimb; Homovanillic Acid; Membrane Glycoproteins; Membrane Transport Proteins; Movement; Nerve Tissue Proteins; Neuropeptides; Oxidopamine; Parkinsonian Disorders; Physical Exertion; Rats; Rats, Long-Evans; Restraint, Physical; Tyrosine 3-Monooxygenase; Vesicular Biogenic Amine Transport Proteins | 2002 |
PNU-96391A (OSU6162) antagonizes the development of behavioral sensitization induced by dopamine agonists in a rat model for Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Brain Chemistry; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Homovanillic Acid; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease, Secondary; Piperidines; Quinpirole; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Sympathectomy, Chemical; Sympatholytics | 2002 |
Differences in dopaminergic neuroprotective effects of estrogen during estrous cycle.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chlorides; Diestrus; Dopamine; Dopamine Plasma Membrane Transport Proteins; Estradiol; Estrogens; Estrous Cycle; Female; Ferric Compounds; Free Radicals; Homovanillic Acid; Injections; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxins; Oxidopamine; Parkinsonian Disorders; Proestrus; Rats; Rats, Wistar; Substantia Nigra | 2003 |
Potentiation of parkinsonian symptoms by depletion of locus coeruleus noradrenaline in 6-hydroxydopamine-induced partial degeneration of substantia nigra in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Behavior, Animal; Benzylamines; Catalepsy; Disease Models, Animal; Dopamine; Dopamine Antagonists; Drug Interactions; Haloperidol; Hippocampus; Homovanillic Acid; Hypothalamus; Locus Coeruleus; Male; Medial Forebrain Bundle; Nerve Degeneration; Neurotoxins; Norepinephrine; Oxidopamine; Parkinsonian Disorders; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reaction Time; Serotonin; Substantia Nigra; Thalamus; Tyrosine | 2003 |
Behavioral and neurochemical effects of noradrenergic depletions with N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine in 6-hydroxydopamine-induced rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Basal Ganglia; Behavior, Animal; Benzylamines; Brain Chemistry; Catalepsy; Disease Models, Animal; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Locus Coeruleus; Male; Motor Activity; Norepinephrine; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Serotonin; Statistics, Nonparametric; Tyrosine | 2004 |
Ironing iron out in Parkinson's disease and other neurodegenerative diseases with iron chelators: a lesson from 6-hydroxydopamine and iron chelators, desferal and VK-28.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Brain; Brocresine; Chromatography, High Pressure Liquid; Deferoxamine; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Exploratory Behavior; Functional Laterality; Homovanillic Acid; Iron; Iron Chelating Agents; Levodopa; Male; Motor Activity; Neurodegenerative Diseases; Neurotransmitter Agents; Oxidopamine; Parkinson Disease; Piperazines; Quinolines; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |
Rasagiline enhances L-DOPA-induced contralateral turning in the unilateral 6-hydroxydopamine-lesioned guinea-pig.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Dopamine; Functional Laterality; Guinea Pigs; Homovanillic Acid; Indans; Male; Models, Neurological; Monoamine Oxidase Inhibitors; Motor Activity; Neuroprotective Agents; Oxidopamine; Reproducibility of Results; Substantia Nigra | 2004 |
Novel dopamine releasing response of an anti-convulsant agent with possible anti-Parkinson's activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Antiparkinson Agents; Behavior, Animal; Carbidopa; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Homovanillic Acid; Isoxazoles; Levodopa; Microdialysis; Oxidopamine; Parkinson Disease; Rats; Zonisamide | 2004 |
Sparing of behavior and basal extracellular dopamine after 6-hydroxydopamine lesions of the nigrostriatal pathway in rats exposed to a prelesion sensitizing regimen of amphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Brain Diseases; Cell Count; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Extracellular Space; Homovanillic Acid; Immunohistochemistry; Male; Microdialysis; Oxidopamine; Physical Conditioning, Animal; Psychomotor Performance; Rats; Rats, Long-Evans; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2004 |
AMPA receptor blockade potentiates the stimulatory effect of L-DOPA on dopamine release in dopamine-deficient corticostriatal slice preparation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzodiazepines; Cerebral Cortex; Dopamine; Dopamine Agents; Electric Stimulation; Homovanillic Acid; In Vitro Techniques; Levodopa; Neostriatum; Oxidopamine; Rats; Receptors, AMPA; Sympatholytics | 2004 |
Dopamine agonist cabergoline inhibits levodopa-induced caspase activation in 6-OHDA-lesioned mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Cabergoline; Carbidopa; Caspases; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Agonists; Drug Combinations; Drug Interactions; Enzyme Activation; Ergolines; Glutathione; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred ICR; Neurotoxicity Syndromes; Oxidopamine; Thiobarbituric Acid Reactive Substances | 2005 |
Effect of AdGDNF on dopaminergic neurotransmission in the striatum of 6-OHDA-treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Drug Interactions; Glial Cell Line-Derived Neurotrophic Factor; Homovanillic Acid; Male; Microdialysis; Nerve Growth Factors; Oxidopamine; Potassium Chloride; Rats; Rats, Inbred F344; Time Factors; Tyrosine 3-Monooxygenase | 2005 |
Pramipexole has ameliorating effects on levodopa-induced abnormal dopamine turnover in parkinsonian striatum and quenching effects on dopamine-semiquinone generated in vitro.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Antiparkinson Agents; Benzoquinones; Benzothiazoles; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electron Spin Resonance Spectroscopy; Functional Laterality; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred ICR; Oxidopamine; Parkinson Disease; Pramipexole; Thiazoles; Time Factors | 2005 |
Neuroprotection by crocetin in a hemi-parkinsonian rat model.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Carotenoids; Catalase; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Homovanillic Acid; Male; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Substantia Nigra; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vitamin A | 2005 |
Zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butanone] prevents 6-hydroxydopamine-induced dopamine depression in mouse striatum and increases superoxide scavenging activity in serum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catalase; Dopamine; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Glutathione Peroxidase; Guaiacol; Homovanillic Acid; Hydroxyl Radical; Male; Mice; Mice, Inbred ICR; Neostriatum; Nerve Tissue Proteins; Oxidopamine; Superoxides; Sympatholytics | 2005 |
Effects of anaesthetics on the loss of nigrostriatal dopaminergic neurons by 6-hydroxydopamine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Analysis of Variance; Anesthetics; Animals; Cell Count; Cell Death; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Homovanillic Acid; Immunohistochemistry; Male; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase | 2006 |
Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Curcumin; Disease Models, Animal; Dopamine; Flavanones; Flavonoids; Flavonols; Homovanillic Acid; Male; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Phenols; Quercetin; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2005 |
Further validation of the corridor task for assessing deficit and recovery in the hemi-Parkinsonian rat: restoration of bilateral food retrieval by dopamine receptor agonism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Feeding Behavior; Functional Laterality; Homovanillic Acid; Oxidopamine; Parkinson Disease; Rats; Recovery of Function; Reproducibility of Results | 2006 |
Increased slow oscillatory activity in substantia nigra pars reticulata triggers abnormal involuntary movements in the 6-OHDA-lesioned rat in the presence of excessive extracellular striatal dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Dyskinesias; Extracellular Fluid; Homovanillic Acid; Levodopa; Male; Membrane Potentials; Microdialysis; Neurons; Oxidopamine; Rats; Rats, Wistar; Substantia Nigra | 2006 |
Protease-activated receptor-1 mediates protection elicited by thrombin preconditioning in a rat 6-hydroxydopamine model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Biotransformation; Catecholamines; Forelimb; Homovanillic Acid; Male; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Receptors, Thrombin; Sympatholytics; Thrombin; Vibrissae | 2006 |
Selective activation of group III metabotropic glutamate receptors by L-(+)-2-amino-4-phosphonobutryic acid protects the nigrostriatal system against 6-hydroxydopamine toxicity in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aminobutyrates; Animals; Corpus Striatum; gamma-Aminobutyric Acid; Homovanillic Acid; Male; Neuroprotective Agents; Oxidopamine; Phosphoserine; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Substantia Nigra | 2007 |
Effects of 2,3-benzodiazepine AMPA receptor antagonists on dopamine turnover in the striatum of rats with experimental parkinsonism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Benzodiazepines; Corpus Striatum; Dopamine; Dopamine Agents; Drug Interactions; Functional Laterality; Homovanillic Acid; Levodopa; Male; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 2007 |
The regulation of liver cytochrome p450 by the brain dopaminergic system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Blotting, Western; Brain; Brain Chemistry; Cytochrome P-450 Enzyme System; Dopamine; Gene Expression Regulation, Enzymologic; Homovanillic Acid; In Vitro Techniques; Isoenzymes; Limbic System; Liver; Male; Neostriatum; Oxidopamine; Rats; Rats, Wistar; Signal Transduction; Sympatholytics | 2007 |
High-frequency stimulation of the subthalamic nucleus prolongs the increase in striatal dopamine induced by acute l-3,4-dihydroxyphenylalanine in dopaminergic denervated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Data Interpretation, Statistical; Denervation; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Electric Stimulation; Extracellular Space; Homovanillic Acid; Male; Microdialysis; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley; Subthalamic Nucleus; Synaptic Transmission | 2007 |
Modulation of the motor response to dopaminergic drugs in a parkinsonian model of combined dopaminergic and noradrenergic degeneration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Adrenergic Agents; Animals; Antiparkinson Agents; Behavior, Animal; Benzylamines; Brain; Caffeine; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Male; Motor Activity; Neurotoxins; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley | 2007 |
Intrastriatal inhibition of aromatic amino acid decarboxylase prevents l-DOPA-induced dyskinesia: a bilateral reverse in vivo microdialysis study in 6-hydroxydopamine lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic-L-Amino-Acid Decarboxylases; Behavior, Animal; Benserazide; Brain Injuries; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Drug Interactions; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Homovanillic Acid; Levodopa; Male; Microdialysis; Oxidopamine; Rats; Rats, Wistar | 2008 |
Echinacoside prevents the striatal extracellular levels of monoamine neurotransmitters from diminution in 6-hydroxydopamine lesion rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Glycosides; Homovanillic Acid; Male; Oxidopamine; Rats; Rats, Wistar | 2007 |
Evaluation of estrogen neuroprotective effect on nigrostriatal dopaminergic neurons following 6-hydroxydopamine injection into the substantia nigra pars compacta or the medial forebrain bundle.
Topics: Animals; Cell Survival; Dopamine; Drug Implants; Estradiol; Estrogens; Female; Homovanillic Acid; Medial Forebrain Bundle; Microinjections; Neurons; Neuroprotective Agents; Ovariectomy; Oxidopamine; Pregnancy; Rats; Substantia Nigra; Sympathomimetics | 2008 |
The vermicelli handling test: a simple quantitative measure of dexterous forepaw function in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Food; Forelimb; Homovanillic Acid; Infarction, Middle Cerebral Artery; Male; Motor Cortex; Motor Skills; Neostriatum; Observer Variation; Oxidopamine; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Stereotaxic Techniques; Sympatholytics | 2008 |
Neurochemical changes in the striatum of dyskinetic rats after administration of the cannabinoid agonist WIN55,212-2.
Topics: Amphetamine; Animals; Benzoxazines; Calcium Channel Blockers; Cannabinoids; Corpus Striatum; Dopamine; Dyskinesias; Glutamine; Homovanillic Acid; Levodopa; Male; Morpholines; Naphthalenes; Oxidopamine; Rats; Rats, Wistar | 2009 |
Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Docosahexaenoic Acids; Dopamine; Homovanillic Acid; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Neostriatum; Oxidative Stress; Oxidopamine; Thiobarbituric Acid Reactive Substances | 2009 |
Ketogenic diet protects dopaminergic neurons against 6-OHDA neurotoxicity via up-regulating glutathione in a rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Diet, Ketogenic; Dopamine; Glutathione; Homovanillic Acid; Immunohistochemistry; Nerve Degeneration; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Tyrosine 3-Monooxygenase; Up-Regulation | 2009 |
Biochemical alteration in cerebrospinal fluid precedes behavioral deficits in Parkinsonian rats induced by 6-hydroxydopamine.
Topics: Animals; Biomarkers; Cell Count; Cell Death; Disease Models, Animal; Dopamine; Homovanillic Acid; Hypokinesia; Male; Muscle Rigidity; Nerve Degeneration; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Substantia Nigra; Sympatholytics | 2009 |
Therapeutic effect of human amniotic epithelial cell transplantation into the lateral ventricle of hemiparkinsonian rats.
Topics: Amnion; Animals; Apomorphine; Chromatography, High Pressure Liquid; Epithelial Cells; Female; Homovanillic Acid; Humans; Immunohistochemistry; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley | 2009 |
Pre-synaptic glutamate-induced activation of DA release in the striatum after partial nigral lesion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Brain Injuries; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Electrochemotherapy; Glutamic Acid; Homovanillic Acid; Male; Microdialysis; Oxidopamine; Presynaptic Terminals; Rats; Rats, Wistar; Substantia Nigra | 2010 |
On the role of P2X(7) receptors in dopamine nerve cell degeneration in a rat model of Parkinson's disease: studies with the P2X(7) receptor antagonist A-438079.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Analysis of Variance; Animals; Brain; Cell Count; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Glial Fibrillary Acidic Protein; Homovanillic Acid; Male; Nerve Degeneration; Neural Pathways; Oxidopamine; Parkinson Disease; Purinergic P2 Receptor Antagonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Statistics, Nonparametric; Tetrazoles | 2010 |
Salicylic acid protects against chronic L-DOPA-induced 6-OHDA generation in experimental model of parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Male; Medial Forebrain Bundle; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Salicylates | 2010 |
Neurturin protects against 6-hydroxydopamine-induced reductions in evoked dopamine overflow in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Functional Laterality; Glial Cell Line-Derived Neurotrophic Factor; Homovanillic Acid; Male; Microdialysis; Nerve Growth Factors; Neuroprotective Agents; Neurturin; Oxidopamine; Potassium Chloride; Rats; Rats, Inbred F344; Substantia Nigra; Sympatholytics | 2010 |
Chronic progesterone treatment of male rats with unilateral 6-hydroxydopamine lesion of the dorsal striatum exacerbates [corrected] parkinsonian symptoms.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Progesterone; Rats; Rats, Wistar | 2011 |
Intranasally applied L-DOPA alleviates parkinsonian symptoms in rats with unilateral nigro-striatal 6-OHDA lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Intranasal; Amphetamine; Analysis of Variance; Animals; Antiparkinson Agents; Benserazide; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Electrochemistry; Exploratory Behavior; Forelimb; Functional Laterality; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Motor Activity; Motor Skills; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Substantia Nigra; Sympatholytics | 2012 |
Contralateral retinal dopamine decrease and melatonin increase in progression of hemiparkinsonium rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Disease Progression; Dopamine; Homovanillic Acid; Melatonin; Oxidopamine; Parkinson Disease; Rats; Retina; Spectrometry, Fluorescence | 2012 |
Prostaglandin E2-mediated attenuation of mesocortical dopaminergic pathway is critical for susceptibility to repeated social defeat stress in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Benzazepines; Calcium-Binding Proteins; Corticosterone; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Disease Susceptibility; Dominance-Subordination; Dopamine; Dopamine Antagonists; Homovanillic Acid; Interpersonal Relations; Maze Learning; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Microfilament Proteins; Neural Pathways; Oxidopamine; Prefrontal Cortex; Pyrazoles; Receptors, Prostaglandin E; Signal Transduction; Stress, Psychological; Sulfonamides; Time Factors; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2012 |
Increased melatonin may play dual roles in the striata of a 6-hydroxydopamine model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Data Interpretation, Statistical; Disease Models, Animal; Dopamine; Homovanillic Acid; Male; Melatonin; Microdialysis; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley | 2013 |
GABAA-receptor activation in the subthalamic nucleus compensates behavioral asymmetries in the hemiparkinsonian rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Animals; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Functional Laterality; GABA-A Receptor Agonists; Homovanillic Acid; Male; Medial Forebrain Bundle; Mental Disorders; Muscimol; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Receptors, GABA-A; Statistics, Nonparametric; Subthalamic Nucleus; Time Factors | 2013 |
Neuroprotective effect of hydroxysafflor yellow A on 6-hydroxydopamine-induced Parkinson's disease in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Chalcone; Gene Expression Regulation, Enzymologic; Homovanillic Acid; Male; Neostriatum; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Quinones; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Tyrosine 3-Monooxygenase | 2013 |
The subthalamic activity and striatal monoamine are modulated by subthalamic stimulation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Action Potentials; Animals; Biogenic Monoamines; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Electric Stimulation; Female; Homovanillic Acid; Motor Activity; Neurons; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Spectrum Analysis; Subthalamic Nucleus | 2014 |
Ontogenetic manganese exposure with perinatal 6-OHDA lesioning alters behavioral responses of rats to dopamine D₁ and D2 agonist treatments.
Topics: Animals; Behavior, Animal; Desipramine; Dopamine; Dopamine Agonists; Exploratory Behavior; Female; Homovanillic Acid; Manganese; Maternal-Fetal Exchange; Motor Activity; Neostriatum; Oxidopamine; Pargyline; Parkinson Disease; Pregnancy; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2014 |
A potential target for the treatment of Parkinson's disease: effect of lateral habenula lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Habenula; Homovanillic Acid; Male; Medial Forebrain Bundle; Neurosurgery; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2014 |
AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Dependovirus; Disease Models, Animal; Dopaminergic Neurons; Down-Regulation; Genetic Vectors; Homovanillic Acid; Lim Kinases; Nerve Degeneration; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rats; Rats, Wistar; rho-Associated Kinases; RNA, Small Interfering; Substantia Nigra; Tyrosine 3-Monooxygenase | 2015 |
Decreased behavioral response to intranigrally administered GABAA agonist muscimol in the lactacystin model of Parkinson's disease may result from partial lesion of nigral non-dopamine neurons: comparison to the classical neurotoxin 6-OHDA.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Animals; Cell Count; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; GABA-A Receptor Agonists; Homovanillic Acid; Locomotion; Male; Muscimol; Neurons; Oxidopamine; Parkinson Disease; Parkinsonian Disorders; Rats, Wistar; Receptors, GABA-A; Substantia Nigra | 2015 |
Differential degradation of motor deficits during gradual dopamine depletion with 6-hydroxydopamine in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Homovanillic Acid; Male; Medial Forebrain Bundle; Mice; Mice, Inbred C57BL; Movement Disorders; Norepinephrine; Oxidopamine; Psychomotor Performance; Serotonin; Time Factors | 2015 |
Protective role of chrysin on 6-hydroxydopamine-induced neurodegeneration a mouse model of Parkinson's disease: Involvement of neuroinflammation and neurotrophins.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biomarkers; Dopamine; Flavonoids; Gene Expression Regulation; Homovanillic Acid; Inflammation; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factors; Oxidopamine; Parkinson Disease, Secondary; Random Allocation | 2018 |
Therapeutic efficacy of regulable GDNF expression for Huntington's and Parkinson's disease by a high-induction, background-free "GeneSwitch" vector.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Disease Models, Animal; Gene Expression Regulation; Glial Cell Line-Derived Neurotrophic Factor; Green Fluorescent Proteins; Homovanillic Acid; Hormone Antagonists; Huntingtin Protein; Huntington Disease; Mice; Mice, Transgenic; Mifepristone; Oxidopamine; Parkinson Disease; Synapsins; Synucleins; Transduction, Genetic | 2018 |
Chrysin protects against behavioral, cognitive and neurochemical alterations in a 6-hydroxydopamine model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cognition; Dopamine; Female; Flavonoids; Homovanillic Acid; Lipid Peroxidation; Maze Learning; Mice; Neuroprotective Agents; Nitric Oxide Synthase; Oxidative Stress; Oxidopamine; Parkinson Disease, Secondary; Reactive Oxygen Species | 2019 |