homoserine and pseudomonas aeruginosa autoinducer

homoserine has been researched along with pseudomonas aeruginosa autoinducer in 197 studies

Research

Studies (197)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (7.61)18.2507
2000's65 (32.99)29.6817
2010's102 (51.78)24.3611
2020's15 (7.61)2.80

Authors

AuthorsStudies
Bycroft, BW; Foglino, M; Latifi, A; Lazdunski, A; Stewart, GS; Williams, P; Winson, MK1
Eberhard, A; Gray, KM; Greenberg, EP; Iglewski, BH; Passador, L; Pearson, JP; Tucker, KD1
Iglewski, BH; Pesci, EC; Rust, L1
Guertin, KR; Iglewski, BH; Journet, MP; Kende, AS; Passador, L; Tucker, KD1
Iglewski, BH; Pearson, JP; Pesci, EC1
Appleby, P; Bycroft, BW; Pritchard, DI; Sewell, H; Stewart, GS; Telford, G; Tomkins, PT; Wheeler, D; Williams, P1
Costerton, JW; Davies, DG; Greenberg, EP; Iglewski, BH; Parsek, MR; Pearson, JP1
Kolter, R; Losick, R1
Doroques, DB; Frank, DW; Gropper, MA; Kurahashi, K; Long, T; Ohara, M; Sawa, T; Twining, SS; Wiener-Kronish, JP1
Bouillant, ML; Nasser, W; Reverchon, S; Salmond, G1
Winans, SC1
Hoang, TT; Schweizer, HP1
Brun, P; Figarella, C; Kammouni, W; Lazdunski, A; Marchand-Pinatel, S; Merten, MD; Saleh, A; Tubul, A1
Bycroft, B; Camara, M; Chhabra, SR; Dunn, WR; Lawrence, RN; Williams, P; Wilson, VG1
Burnett, S; Elkins, JG; Fredericks, J; Hassett, DJ; Huang, CT; Iglewski, BH; Ma, JF; McDermott, TR; McFeters, G; Ochsner, UA; Passador, L; Stewart, PS; West, SE1
Holden, I; Swift, I; Williams, I1
Cámara, M; Chalker, VJ; Hardman, A; Kirke, D; Milton, DL; Williams, P1
Ceri, H; Parkins, MD; Storey, DG1
Fedyk, ER; Iglewski, BH; Mukaida, N; Phipps, RP; Smith, RS; Springer, TA1
Bennett, T; Bycroft, BW; Chhabra, SR; Gardiner, SM; Harty, C; Pritchard, DI; Williams, P1
Harris, SG; Iglewski, B; Phipps, R; Smith, RS1
Blanc, D; Favre-Bonté, S; Pache, JC; Pechère, JC; Robert, J; van Delden, C1
Croft, JM; King, JR; Koerber, AJ; Sockett, RE; Ward, JP; Williams, P1
Iglewski, BH; Kelly, R; Phipps, RP; Smith, RS1
Bycroft, BW; Chhabra, SR; Daykin, M; Harty, C; Hooi, DS; Pritchard, DI; Telford, G; Williams, P1
Brooks, AI; Bushnell, D; Iglewski, BH; Passador, L; Wagner, VE1
Bu, Y; Smith, KM; Suga, H1
Cooley, MA; Rice, SA; Ritchie, AJ; Tanabe, KM; Yam, AO1
Horikawa, M; Ishiguro, M; Ishii, Y; Matsumoto, T; Miyairi, S; Pechere, JC; Standiford, TJ; Tateda, K; Yamaguchi, K1
Buch, C; Gram, L; Larsen, JL; Nielsen, J; Sigh, J1
Chun, CK; Greenberg, EP; Ozer, EA; Welsh, MJ; Zabner, J1
Hastings, JW1
Charlton, T; Fagerlind, MG; Harlén, M; James, S; Kjelleberg, S; Nilsson, P; Rice, SA1
Carty, NL; Griswold, JA; Hamood, AN; Patterson, EK; Rumbaugh, KP; Williams, SC1
Higashiyama, Y; Hirakata, Y; Imamura, Y; Kadota, J; Kohno, S; Miyazaki, Y; Mizuta, Y; Ohno, H; Seki, M; Tomono, K; Tsukamoto, K; Yanagihara, K1
Bycroft, BW; Chhabra, SR; Hooi, DS; Pritchard, DI; Williams, P1
Dutton, JM; Glansdorp, FG; Lee, JK; Salmond, GP; Spring, DR; Thomas, GL; Welch, M1
Hogan, DA; Kolter, R; Vik, A1
Cámara, M; Daykin, M; Joint, I; Milton, DL; Tait, K; Williams, P1
Cooley, MA; Jansson, A; Lysaght, P; Nilsson, P; Ritchie, AJ; Stallberg, J1
Bell, KS; Birch, PR; Carr, JP; Harris, SJ; Hyman, LJ; Matlin, AJ; Pemberton, CL; Robson, ND; Salmond, GP; Sebaihia, M; Toth, IK; Whitehead, NA1
Dong, YH; Greenberg, EP; Soo, HM; Zhang, LH; Zhang, XF1
Angelino, NJ; Chow, KC; Dolnick, BJ; Dolnick, R; Stephanie, LV; Sufrin, JR; Wu, Q1
Anguige, K; King, JR; Ward, JP1
Magnusson, KE; Pivoriūnas, A; Vikström, E1
Cámara, M; Chhabra, SR; Dessaux, Y; Oger, P; Uroz, S; Williams, P1
Brown, A; Bycroft, BW; Chhabra, SR; Pritchard, DI; Todd, I; Williams, P; Wood, P1
Cámara, M; Chhabra, SR; Cockayne, A; Hill, P; Middleton, B; Muharram, SH; O'Shea, P; Qazi, S; Williams, P1
Atkinson, S; Cámara, M; Sockett, RE; Williams, P1
Horikawa, M; Ishiguro, M; Ishii, Y; Miyairi, S; Takabatake, T; Tateda, K; Tuzuki, E; Ueda, C; Yamaguchi, K1
Pritchard, DI1
Ader, F; Faure, K; Guery, B; Le Berre, R; Nguyen, S; Pierre, M1
Brader, G; Koch, G; Palva, ET; Sjöblom, S1
Calfee, MW; Carty, NL; Colmer-Hamood, JA; Hamood, AN; Layland, N; Pesci, EC1
Brenner-Weiss, G; Hänsch, GM; Hug, F; Obst, U; Prior, B; Wagner, C; Zimmermann, S1
Bryan, A; Gyorke, S; Li, G; Martinez-Zaguilan, R; Rumbaugh, KP; Sennoune, S; Shiner, EK; Terentyev, D; Williams, SC1
Brenner-Weiss, G; Hänsch, GM; Hug, F; Müller, W; Obst, U; Prior, B; Wagner, C; Zimmermann, S1
Fuse, ET; Horikawa, M; Ishiguro, M; Ishii, Y; Miyairi, S; Saito, H; Standiford, TJ; Takabatake, T; Tateda, K; Ueda, C; Yamaguchi, K1
Duerkop, BA; Greenberg, EP; Hanzelka, BL; Hare, BJ; Heim, R; Müh, U; Olson, ER; Schuster, M1
Bourquard, N; Lusis, AJ; Ng, CJ; Ozer, EA; Parsek, MR; Reddy, ST; Shih, DM; Stoltz, DA; Yu, JM; Zabner, J1
Kirschhöfer, F; Marten, SM; Nusser, M; Obst, U; Schwartz, T; Walter, S1
Magnusson, KE; Tafazoli, F; Vikström, E1
Ikeda, T; Ishida, T; Kato, J; Kuroda, A; Ohtake, H; Takiguchi, N1
Chamot, E; Favre-Bonté, S; Köhler, T; Romand, JA; van Delden, C1
Bryan, A; Do, C; Jahoor, A; Krier, J; Li, G; Patel, R; Rumbaugh, KP; Wahli, W; Watters, C; Williams, SC1
Janda, KD; Kaufmann, GF; Mee, JM; Park, J; Ulevitch, RJ1
Chowdhary, PK; Draganov, DI; Haines, DC; Haley, RW; Horke, S; Kramer, GL; Teiber, JF; Xiao, J1
Boontham, P; Cámara, M; Chandran, P; Chuthapisith, S; Eremin, O; McKechnie, A; Pritchard, D; Robins, A; Rowlands, BJ; Williams, P1
Adeltoft, D; Bjarnsholt, T; Givskov, M; Ifversen, P; Kristiansen, S1
Conibear, TC; Thuruthyil, SJ; Willcox, MD; Zhu, H1
Janda, KD; Kaufmann, GF; Park, J1
Grauer, DC; Janda, KD; Katz, AZ; Kaufmann, GF; Kravchenko, VV; Lehmann, M; Mathison, JC; Meijler, MM; Scott, DA; Ulevitch, RJ1
de la Vega, L; Schmitz, ML1
Bui, L; Konradsson, P; Magnusson, KE; Vikström, E1
Brix, S; Cooley, M; Diggle, SP; Fink, LN; Froekiaer, H; Givskov, M; Lazenby, J; Skindersoe, ME; Whittall, C; Williams, P; Zeuthen, LH1
Kim, C; Kim, CK; Kim, J; Lee, JH; Park, HJ; Park, HY; Yoon, J1
Chen, J; Li, H; Lu, Z; Mao, Y; Song, J; Wang, L; Xia, C; Xie, X; Ye, L1
Gotoh, N; Horikawa, M; Ishiguro, M; Ishii, Y; Kimura, S; Miyairi, S; Tateda, K; Yamaguchi, K1
Dietl, J; Frambach, T; Hennicke, F; Rennemeier, C; Staib, P1
Koch, G; Nadal-Jimenez, P; Papaioannou, E; Quax, WJ; Setroikromo, R; Wahjudi, M1
Coenye, T; Cool, RH; Jimenez, PN; Koch, G; Krzeslak, J; Papaioannou, E; Quax, WJ; Wahjudi, M1
Horikawa, M; Inoue, Y; Ishiguro, M; Ishii, Y; Kimura, S; Miyairi, S; Nomura, K; Suematsu, T; Tateda, K; Ueda, C; Yamada, K; Yamaguchi, K1
Altenhöfer, S; Chowdhary, PK; Förstermann, U; Goldeck, M; Haines, DC; Haley, RW; Horke, S; Kramer, GL; Teiber, JF; Wilgenbus, P; Witte, I; Xiao, J1
Cooley, MA; Rolph, MS; Whittall, C1
Collet, A; Cosette, P; Jouenne, T; Junter, GA; Nigaud, Y; Song, PC; Vaudry, D; Vaudry, H1
Buddrus-Schiemann, K; Fekete, A; Fischer, D; Hartmann, A; Hense, BA; Kuttler, C; Lucio, M; Müller, J; Rothballer, M; Schmitt-Kopplin, P1
Karatuna, O; Yagci, A1
Barrett, DA; Cámara, M; Cifelli, PM; Erskine, P; Givskov, M; Holland, ED; Knox, A; Lewis, S; Ortori, CA; Righetti, K; Smyth, AR; Williams, P1
Chen, J; Li, G; Li, H; Mao, Y; Song, J; Wang, L; Xia, C; Xie, X; Ye, L1
Bryan, A; Koenig, L; Li, G; Olmos, A; Rumbaugh, KP; Watters, C; Williams, SC; Youn, E1
Bertani, I; Bigirimana, J; Cabrio, L; Ferluga, S; Guarnaccia, C; Maraite, H; Mattiuzzo, M; Pongor, S; Venturi, V1
Chai, H; Hazawa, M; Hosokawa, Y; Igarashi, J; Kashiwakura, I; Shirai, N; Suga, H; Takahashi, K1
Janda, KD; Kaufmann, GF; Lowery, CA1
Kaufmann, GF; Kravchenko, VV; Ulevitch, RJ1
Cornelis, P; Crabbé, A; Leys, N; Nickerson, CA; Ott, CM; Sarker, SF; Van Houdt, R1
Abell, C; Bowden, SD; Hodgkinson, JT; Hollfelder, F; Huck, WT; Patil, SN; Shim, JU; Spring, DR; Welch, M1
Blohmke, CJ; Hancock, RE; Mayer, ML; Sheridan, JA; Turvey, SE1
Baldrich, E; García-Aljaro, C; Muñoz, FX1
Imperi, F; Leoni, L; Massai, F; Quattrucci, S; Visca, P; Zennaro, E1
Cool, RH; Hendrawati, O; Papaioannou, E; Poelarends, GJ; Quax, WJ; van Assen, AHG; van Merkerk, R; Wahjudi, M1
Seet, Q; Zhang, LH1
Akase, T; Asada, M; Huang, L; Ikeda, T; Minematsu, T; Morohoshi, T; Nagase, T; Nakagami, G; Ohta, Y; Sanada, H1
Chhabra, SR; Fischer, PM; Hooi, DS; Jadhav, GP; Kellam, B; Pritchard, DI; Righetti, K; Telford, G; Williams, P1
Horikawa, M; Hosono Honda, N; Ishiguro, M; Ishii, Y; Kimura, S; Miyairi, S; Tateda, K; Ueda, C; Yamaguchi, K1
Brackman, SM; Chopra, AK; Khajanchi, BK; Kirtley, ML1
Baucher, M; Diallo, B; Duez, P; El Jaziri, M; Kiendrebeogo, M; Mol, A; Rajaonson, S; Rasamiravaka, T; Stévigny, C; Vandeputte, OM1
Cooke, A; Gaisford, W; Pritchard, DI1
De Angelis, MG; Galli, D; Magni, P; Pasotti, L; Quattrocelli, M1
Berliner, JA; Bourquard, N; Gong, KW; Grijalva, V; Kim, JB; Lee, S; Lusis, AJ; Meng, Y; Port, Z; Reddy, ST; Romanoski, CE; Shi, YS; Shih, DM; Xia, YR1
Chang, MW; Leong, SS; Ling, H; Lo, TM; Nguyen, HX; Poh, CL; Saeidi, N; Wong, CK1
Jarosz, LM; Krom, BP; Meijler, MM; Ovchinnikova, ES1
Fu, Z; Hum, L; Illek, B; Kong, W; Lopez-Guzman, M; Lynch, SV; Machen, TE; Patanwala, M; Schwarzer, C1
Balamurugan, K; Musthafa, KS; Pandian, SK; Ravi, AV1
Brenner-Weiss, G; Hänsch, GM; Kahle, NA; Obst, U; Overhage, J1
Gotoh, N; Horikawa, M; Inami, H; Kato, T; Minagawa, S; Miyairi, S; Okuda, J; Sawada, S; Yasuki, T1
Huang, D; Lin, Y; Liu, W; Lu, Q; Yang, X; Zhang, X; Zhong, H1
Canning, BJ; Krasteva, G; Kummer, W; Papadakis, T1
Huang, L; Minematsu, T; Nagase, T; Nakagami, G; Paes, C; Sanada, H; Sari, Y1
Bobkiewicz, W; Boller, K; Ebinger, S; Husmann, M; Janda, KD; Kloft, N; Neukirch, C; von Hoven, G; Weis, S1
Bartolucci, N; Della Valle, M; Galloway, WR; Hodgkinson, JT; Ibbeson, BM; Morkunas, B; O'Connell, KM; Spring, DR; Welch, M; Wright, M1
Karlsson, T; Magnusson, KE; Turkina, MV; Vikström, E; Yakymenko, O1
Dy, RL; Hynes, MF; Komarovsky, VM; Major, AS; Ramsay, JP; Ronson, CW; Salmond, GP; Sullivan, JT1
Garner, AL; Janda, KD; Kaufmann, GF; Kravchenko, VV; Struss, AK; Yu, J1
Gotoh, N; Hatanaka, A; Hayashi, D; Imai, Y; Ishii, K; Kanno, E; Kawakami, K; Maruyama, R; Miyairi, S; Otomaru, H; Sato, S; Shibuya, N; Tachi, M; Tanno, H1
Abell, C; Bai, Y; Bowden, SD; Huck, WT; Pan, J; Patil, SN; Poulter, S; Salmond, GP; Welch, M1
Bourquard, N; Devarajan, A; Ganapathy, E; Gao, F; Grijalva, VR; Reddy, ST; Verma, J1
Delago, A; Inbal, B; Krief, P; Meijler, MM; Rabin, N1
Boon, C; Chen, S; Deng, Y; Lim, A; Zhang, LH1
Bezirtzoglou, E; Bleotu, C; Chifiriuc, MC; Holban, AM; Lazar, V1
Martínez, JL1
András, IE; Bertrand, L; Eum, SY; Jaraki, D; Toborek, M1
Ishizuka, S; Joe, GH; Maseda, H; Miyazaki, H; Nomura, N; Ohnishi, J; Shimizu, H; Taguchi, R; Tanaka, S1
Bernay, B; Gardères, J; Henry, J; Le Pennec, G; Müller, WE; Ritter, A; Wiens, M; Zatylny-Gaudin, C1
Adrian, TG; Chan, KG; Mohamad, NI; Muhamad Yunos, NY; Tan, PW; Tan, WS; Yin, WF1
Croda-García, G; Grosso-Becerra, MV; Merino, E; Mojica-Espinosa, R; Servín-González, L; Soberón-Chávez, G1
Blackwell, HE; Gerdt, JP; McInnis, CE; Schell, TL1
Bacchetta, M; Chanson, M; Frieden, M; Köhler, T; Losa, D; Saab, JB; van Delden, C1
Fu, Z; Li, C; Machen, TE; Morita, T; Neely, AM; Schwarzer, C; Whitt, AG1
Baba, N; Fukiya, S; Hagio, M; Ishizuka, S; Joe, GH; Lee, JY; Maseda, H; Miyazaki, H; Nomura, N; Nose, T; Shimizu, H; Taguchi, R; Tanaka, S; Yokota, A1
Choi, CH; Oh, MH1
Golpasha, ID; Irani, S; Mousavi, SF; Owlia, P; Siadat, SD1
Byun, Y; Kim, HS; Kim, Y; Ok, K; Park, HD; Park, S1
Horke, S; Kramer, GL; Schütz, EM; Selbach, M; Teiber, JF; Wilgenbus, P; Witte, I; Xiao, J1
Asada, M; Huang, L; Ikeda, S; Ikeda, T; Kanazawa, T; Minematsu, T; Morohoshi, T; Nagase, T; Nakagami, G; Sanada, H; Yamane, T1
Bortolotti, D; Carosella, ED; Di Luca, D; LeMaoult, J; Rizzo, R; Trapella, C1
Gotoh, N; Ishii, K; Kamimatsuno, R; Kanno, E; Kawakami, K; Maruyama, R; Miyairi, S; Miyasaka, T; Suzuki, A; Tachi, M; Takagi, N; Tanno, H1
Burlison, JA; Li, C; Lu, H; Machen, TE; Neely, AM; Schwarzer, C; Stivers, NS; White, C; Whitt, AG; Zhao, G1
Dapunt, U; Gaida, MM; Hänsch, GM1
Brown, JR; Dalchau, N; Federici, F; Grant, PK; Haseloff, J; Patange, O; Phillips, A; Rudge, TJ; Yordanov, B1
Holm, A; Magnusson, KE; Vikström, E1
Liu, J; Luo, Y; Ni, Y; Qian, X; Tao, S; Zhao, R1
Chen, X; Lou, Z; Tang, Y; Wang, H1
Forsythe, P; Han, S; Jang, H; Khambati, I; Pijnenburg, D1
Chrzanowski, Ł; Corvini, PF; Myszka, K; Sznajdrowska, A; Szulc, A; Woźniak-Karczewska, M; Zgoła-Grześkowiak, A; Ławniczak, Ł1
Rousseau, S; Roussel, L1
Borges, A; Borges, F; Gaspar, A; Simões, M; Sousa, P; Vilar, S1
Chen, B; Fang, YL; He, YW; Jin, ZJ; Rampioni, G; Sun, S; Thawai, C; Zhou, L1
Blasco, L; Bou, G; Fernández-García, L; López, M; Mayer, C; Muras, A; Otero, A; Ruiz, FM; Tomás, M1
Agarwal, V; Kalia, M; Mani, A; Narvi, SS; Sharma, D; Singh, PK; Yadav, BS; Yadav, VK1
Amoh, T; Hirota, K; Hori, K; Igarashi, J; Irie, Y; Kariyama, R; Kumon, H; Miyake, Y; Murakami, K; Suga, H; Viducic, D1
Bao, L; Huang, D; Lu, Q; Yu, J; Zhong, H1
Bondí, R; D'Angelo, F; Leoni, L; Longo, F; Messina, M; Rampioni, G; Visca, P1
González-Valdez, A; Morales, E; Servín-González, L; Soberón-Chávez, G1
Aksöz, N; Erdönmez, D; Rad, AY1
Balhouse, BN; Patterson, L; Schmelz, EM; Slade, DJ; Verbridge, SS1
Fussenegger, M; Jaeger, T; Jenal, U; Sedlmayer, F1
Agarwal, V; Dohare, S; Kalia, M; Sharma, D; Singh, PK; Yadav, VK1
Burlison, JA; Li, C; Machen, TE; Meng, S; Neely, AM; Schwarzer, C; Stivers, NS; Whitt, AG; Zhao, G1
Everett, J; Gabrilska, R; Rumbaugh, KP; Vikström, E1
Fang, W; Jiang, D; Jiang, H; Liu, Y; Rao, S; Wu, M; Yuan, L1
Kanemaru, K; Nishimura-Danjobara, Y; Oyama, K; Oyama, Y; Takahashi, K; Yokoigawa, K1
Nishimura-Danjobara, Y; Oyama, K; Oyama, Y; Yokoigawa, K1
Cai, L; Geng, Y; Hua, C; Ni, Y; Niu, L; Tao, S; Zhao, R1
DeLateur, NA; Goldenfeld, N; Karig, D; Lu, T; Martini, KM; Weiss, R1
Agarwal, V; Kalia, M; Sharma, D; Singh, PK; Singh, SK; Yadav, VK1
Turkina, MV; Vikström, E1
Cai, L; Geng, Y; Hua, C; Ni, Y; Sun, Q; Tao, S; Zhao, R1
Amrein, MW; Chen, P; Cheng, J; Fan, Z; Fang, X; Kang, N; Li, N; Li, T; Lin, X; Lü, J; Meng, J; Mu, L; Ren, W; Ruan, H; Shi, Y; Shu, F; Song, D; Tu, Z; Wang, X; Wu, W; Xia, T; Xu, Y; Yan, LT; Zhu, J1
Agarwal, V; Sharma, D; Singh, PK; Singh, SK; Yadav, VK1
Agarwal, V; Kalia, M; Pandey, D; Sharma, D; Singh, PK; Yadav, VK1
Bedi, B; Goldberg, JB; Hart, CM; Koval, M; Maurice, NM; Sadikot, RT; Yuan, Z1
Chen, CY; Chung, YC; Tsai, CT; Tsai, TH; Wang, GH1
Hamamoto, H; Morohoshi, T; Ogasawara, Y; Someya, N; Xie, X1
Guo, J; Ikegame, M; Okamura, H; Yoshida, K1
Bandara, HMHN; Hewavitharana, AK; Samaranayake, LP; Shaw, PN; Smyth, HDC1
Grygier, A; Majcher, M; Myszka, K; Sobieszczańska, N; Szwengiel, A; Wolko, Ł1
Alcalde-Rico, M; Cámara, M; Halliday, N; Martínez, JL; Olivares-Pacheco, J1
Guo, J; Ikegame, M; Kamioka, H; Ochiai, K; Okamura, H; Qiu, L; Uchibe, K; Wang, Z; Weng, Y; Yoshida, K; Yuan, H1
Hu, R; Huang, X; Jin, X; Yuan, K; Zhang, Y; Zhao, Y; Zheng, J; Zhou, J1
Han, D; Pi, Y; Tao, S; Wang, J; Xiong, Y; Zhang, H1
Agarwal, V; Pandey, H; Sharma, D; Singh, PK; Singh, SK; Yadav, VK1
Geng, YF; Mei, J; Sun, YJ; Tao, SN; Yang, C; Zhang, XC; Zhang, Y; Zhao, BT1
Cheng, W; Tan, X; Tao, S; Wang, Z; Wei, H; Wu, Z; Xiong, Y; Yang, Y; Zhang, H; Zhu, X1
Combs, C; Gao, P; Guo, K; Khan, N; Lin, P; Pu, Q; Qin, S; Wang, Z; Wu, M; Xia, Z1
Chen, C; Li, MO; Li, S; Li, Y; Liu, J; Liu, Y; Lu, Y; Luo, Y; Wang, L; Zhang, W; Zhang, X; Zhang, Y1
Ahn, SH; Kim, SH; Oh, DJ; Shin, J1
Afonyushkin, VN; Cherepushkina, VS; Dimova, AS; Donchenko, NA; Koptev, VY; Mironova, TE; Nefedova, EV1

Reviews

5 review(s) available for homoserine and pseudomonas aeruginosa autoinducer

ArticleYear
Immune modulation by Pseudomonas aeruginosa quorum-sensing signal molecules.
    International journal of medical microbiology : IJMM, 2006, Volume: 296, Issue:2-3

    Topics: 4-Butyrolactone; Animals; Cell Communication; Homoserine; Humans; Immunologic Factors; Pseudomonas aeruginosa; Quinolones

2006
[Quorum sensing: a new clinical target for Pseudomonas aeruginosa?].
    Medecine et maladies infectieuses, 2006, Volume: 36, Issue:7

    Topics: Cell Communication; Homoserine; Lactones; Polymorphism, Genetic; Pseudomonas aeruginosa

2006
Modulation of translation and induction of autophagy by bacterial exoproducts.
    Medical microbiology and immunology, 2012, Volume: 201, Issue:4

    Topics: 4-Butyrolactone; Animals; Autophagy; Bacterial Toxins; Eukaryotic Initiation Factor-2; Hemolysin Proteins; Homoserine; Host-Pathogen Interactions; Humans; Phosphorylation; Protein Biosynthesis; Protein Processing, Post-Translational; Pseudomonas aeruginosa; Staphylococcus aureus

2012
Bacteria-Host Crosstalk: Sensing of the Quorum in the Context of Pseudomonas aeruginosa Infections.
    Journal of innate immunity, 2019, Volume: 11, Issue:3

    Topics: 4-Butyrolactone; Bacterial Adhesion; Biofilms; Calcium Signaling; Cell Movement; Homoserine; Host Microbial Interactions; Humans; Iron; Lipopolysaccharides; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing

2019
Quorum sensing molecule N-(3-oxododecanoyl)-l-homoserine lactone: An all-rounder in mammalian cell modification.
    Journal of oral biosciences, 2020, Volume: 62, Issue:1

    Topics: 4-Butyrolactone; Animals; Homoserine; Humans; Lactones; Pseudomonas aeruginosa; Quorum Sensing

2020

Trials

1 trial(s) available for homoserine and pseudomonas aeruginosa autoinducer

ArticleYear
Garlic as an inhibitor of Pseudomonas aeruginosa quorum sensing in cystic fibrosis--a pilot randomized controlled trial.
    Pediatric pulmonology, 2010, Volume: 45, Issue:4

    Topics: 4-Butyrolactone; Adolescent; Adult; Child; Cystic Fibrosis; Female; Garlic; Homoserine; Humans; Male; Middle Aged; Phytotherapy; Pilot Projects; Plant Oils; Plasma; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Respiratory Function Tests; Sputum; Treatment Outcome; Young Adult

2010

Other Studies

191 other study(ies) available for homoserine and pseudomonas aeruginosa autoinducer

ArticleYear
Multiple homologues of LuxR and LuxI control expression of virulence determinants and secondary metabolites through quorum sensing in Pseudomonas aeruginosa PAO1.
    Molecular microbiology, 1995, Volume: 17, Issue:2

    Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Homoserine; Lactones; Ligases; Molecular Sequence Data; Pseudomonas aeruginosa; Repressor Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Trans-Activators; Transcription Factors; Virulence

1995
Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Jan-04, Volume: 91, Issue:1

    Topics: Bacterial Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Homoserine; Lactones; Mass Spectrometry; Pseudomonas aeruginosa; RNA, Messenger

1994
Analysis of the Pseudomonas aeruginosa elastase (lasB) regulatory region.
    Journal of bacteriology, 1996, Volume: 178, Issue:4

    Topics: Bacterial Proteins; Base Sequence; DNA-Binding Proteins; Enzyme Induction; Gene Expression Regulation, Bacterial; Homoserine; Lactones; Metalloendopeptidases; Molecular Sequence Data; Mutagenesis, Site-Directed; Operator Regions, Genetic; Pancreatic Elastase; Promoter Regions, Genetic; Pseudomonas aeruginosa; Regulatory Sequences, Nucleic Acid; Sequence Deletion; Trans-Activators; Transcription, Genetic

1996
Functional analysis of the Pseudomonas aeruginosa autoinducer PAI.
    Journal of bacteriology, 1996, Volume: 178, Issue:20

    Topics: Bacterial Proteins; Binding, Competitive; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Homoserine; Lactones; Metalloendopeptidases; Pseudomonas aeruginosa; Structure-Activity Relationship; Trans-Activators

1996
Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes.
    Journal of bacteriology, 1997, Volume: 179, Issue:18

    Topics: Bacterial Proteins; Binding Sites; DNA-Binding Proteins; DNA, Bacterial; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genes; Genes, Bacterial; Glycolipids; Hexosyltransferases; Homoserine; Lactones; Operon; Pancreatic Elastase; Promoter Regions, Genetic; Pseudomonas aeruginosa; Rhamnose; RNA, Bacterial; Sigma Factor; Signal Transduction; Trans-Activators; Transcription, Genetic

1997
The Pseudomonas aeruginosa quorum-sensing signal molecule N-(3-oxododecanoyl)-L-homoserine lactone has immunomodulatory activity.
    Infection and immunity, 1998, Volume: 66, Issue:1

    Topics: 4-Butyrolactone; Adjuvants, Immunologic; Amino Acid Sequence; Animals; Cell Division; Cells, Cultured; Concanavalin A; Cytotoxicity Tests, Immunologic; Female; Hemocyanins; Homoserine; Humans; Immunoglobulin E; Immunoglobulin G; Interleukin-12; Interleukin-4; Jurkat Cells; Leukocytes, Mononuclear; Lipopolysaccharides; Lymphocytes; Macrophages; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Protein-Tyrosine Kinases; Pseudomonas aeruginosa; Signal Transduction; Spleen; Tumor Necrosis Factor-alpha; Virulence

1998
The involvement of cell-to-cell signals in the development of a bacterial biofilm.
    Science (New York, N.Y.), 1998, Apr-10, Volume: 280, Issue:5361

    Topics: 4-Butyrolactone; Bacterial Adhesion; Bacterial Proteins; Biofilms; Homoserine; Ligases; Mutation; Polysaccharides, Bacterial; Pseudomonas aeruginosa; Sodium Dodecyl Sulfate; Transcription Factors

1998
One for all and all for one.
    Science (New York, N.Y.), 1998, Apr-10, Volume: 280, Issue:5361

    Topics: 4-Butyrolactone; Bacterial Adhesion; Bacterial Physiological Phenomena; Biofilms; Homoserine; Pseudomonas aeruginosa

1998
In vitro cellular toxicity predicts Pseudomonas aeruginosa virulence in lung infections.
    Infection and immunity, 1998, Volume: 66, Issue:7

    Topics: 4-Butyrolactone; Animals; Cell Line; Endopeptidases; Homoserine; Humans; Lung; Lung Diseases; Mice; Pseudomonas aeruginosa; Pseudomonas Infections; Virulence

1998
Characterization of the Erwinia chrysanthemi expI-expR locus directing the synthesis of two N-acyl-homoserine lactone signal molecules.
    Molecular microbiology, 1998, Volume: 29, Issue:6

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Cloning, Molecular; Dickeya chrysanthemi; DNA, Bacterial; Genes, Bacterial; Homoserine; Molecular Sequence Data; Mutation; Pectobacterium carotovorum; Pheromones; Plants; Polygalacturonase; Polysaccharide-Lyases; Signal Transduction; Species Specificity; Trans-Activators

1998
Command, control and communication in bacterial pathogenesis.
    Trends in microbiology, 1998, Volume: 6, Issue:10

    Topics: 4-Butyrolactone; Bacterial Infections; Bacterial Proteins; DNA-Binding Proteins; Homoserine; Pheromones; Pseudomonas aeruginosa; Signal Transduction; Trans-Activators

1998
Characterization of Pseudomonas aeruginosa enoyl-acyl carrier protein reductase (FabI): a target for the antimicrobial triclosan and its role in acylated homoserine lactone synthesis.
    Journal of bacteriology, 1999, Volume: 181, Issue:17

    Topics: 4-Butyrolactone; Acylation; Anti-Infective Agents, Local; Base Sequence; Cloning, Molecular; DNA, Bacterial; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Genes, Bacterial; Genome, Bacterial; Homoserine; Molecular Sequence Data; Oxidoreductases; Pseudomonas aeruginosa; Sequence Analysis, DNA; Triclosan

1999
Pseudomonas aeruginosa quorum-sensing signal molecule N-(3-oxododecanoyl)-L-homoserine lactone inhibits expression of P2Y receptors in cystic fibrosis tracheal gland cells.
    Infection and immunity, 1999, Volume: 67, Issue:10

    Topics: 4-Butyrolactone; Cell Line; Cystic Fibrosis; Homoserine; Humans; Ibuprofen; Pseudomonas aeruginosa; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; RNA, Messenger; Trachea

1999
The Pseudomonas aeruginosa quorum-sensing signal molecule, N-(3-oxododecanoyl)-L-homoserine lactone, inhibits porcine arterial smooth muscle contraction.
    British journal of pharmacology, 1999, Volume: 128, Issue:4

    Topics: 4-Butyrolactone; Animals; Arteries; Female; Homoserine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Pseudomonas aeruginosa; Swine

1999
Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxide.
    Molecular microbiology, 1999, Volume: 34, Issue:5

    Topics: 4-Butyrolactone; Biofilms; Catalase; Gene Expression Regulation, Bacterial; Homoserine; Hydrogen Peroxide; Methylphenazonium Methosulfate; Mutation; Oxidative Stress; Pseudomonas aeruginosa; Signal Transduction; Superoxide Dismutase; Transcription, Genetic

1999
New signal molecules on the quorum-sensing block.
    Trends in microbiology, 2000, Volume: 8, Issue:3

    Topics: 4-Butyrolactone; Bacterial Proteins; Diketopiperazines; DNA-Binding Proteins; Homoserine; Ligases; Piperazines; Pseudomonas aeruginosa; Quinolones; Signal Transduction; Trans-Activators; Transcription Factors

2000
The LuxM homologue VanM from Vibrio anguillarum directs the synthesis of N-(3-hydroxyhexanoyl)homoserine lactone and N-hexanoylhomoserine lactone.
    Journal of bacteriology, 2001, Volume: 183, Issue:12

    Topics: 4-Butyrolactone; Amino Acid Sequence; Animals; Bacterial Proteins; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cloning, Molecular; Escherichia coli; Fish Diseases; Gene Deletion; Genes, Bacterial; Homoserine; Lactones; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Oncorhynchus mykiss; Open Reading Frames; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Signal Transduction; Vibrio; Virulence

2001
Pseudomonas aeruginosa GacA, a factor in multihost virulence, is also essential for biofilm formation.
    Molecular microbiology, 2001, Volume: 40, Issue:5

    Topics: 4-Butyrolactone; Alginates; Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Drug Resistance, Microbial; Glucuronic Acid; Hexuronic Acids; Homoserine; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Virulence

2001
IL-8 production in human lung fibroblasts and epithelial cells activated by the Pseudomonas autoinducer N-3-oxododecanoyl homoserine lactone is transcriptionally regulated by NF-kappa B and activator protein-2.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Jul-01, Volume: 167, Issue:1

    Topics: 4-Butyrolactone; 5' Untranslated Regions; Cell Line; Cell-Free System; Cells, Cultured; Chemotaxis, Leukocyte; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epithelial Cells; Fibroblasts; Homoserine; Humans; Interleukin-8; Lung; Neutrophils; NF-kappa B; Promoter Regions, Genetic; Pseudomonas aeruginosa; Transcription Factor AP-1; Transcription Factor AP-2; Transcription Factors; Transcription, Genetic

2001
Haemodynamic effects of the bacterial quorum sensing signal molecule, N-(3-oxododecanoyl)-L-homoserine lactone, in conscious, normal and endotoxaemic rats.
    British journal of pharmacology, 2001, Volume: 133, Issue:7

    Topics: 4-Butyrolactone; Animals; Antihypertensive Agents; Atenolol; Atrial Function; Atropine; Blood Pressure; Cardiovascular System; Consciousness; Dose-Response Relationship, Drug; Endotoxemia; Heart Atria; Heart Rate; Hemodynamics; Hindlimb; Homoserine; Kidney; Lipopolysaccharides; Male; Mesentery; Rats; Rats, Long-Evans; Regional Blood Flow; Structure-Activity Relationship

2001
The Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)homoserine lactone contributes to virulence and induces inflammation in vivo.
    Journal of bacteriology, 2002, Volume: 184, Issue:4

    Topics: 4-Butyrolactone; Animals; Cells, Cultured; Chemokines; Cyclooxygenase 2; Cytokines; Homoserine; Immunophenotyping; Isoenzymes; Keratinocytes; Lung; Mice; Mice, Inbred C57BL; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Pseudomonas aeruginosa; Skin; T-Lymphocytes; Th1 Cells; Virulence

2002
Detection of Pseudomonas aeruginosa cell-to-cell signals in lung tissue of cystic fibrosis patients.
    Microbial pathogenesis, 2002, Volume: 32, Issue:3

    Topics: 4-Butyrolactone; Adult; Bronchi; Cystic Fibrosis; Female; Homoserine; Humans; Lung; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Signal Transduction

2002
A mathematical model of partial-thickness burn-wound infection by Pseudomonas aeruginosa: quorum sensing and the build-up to invasion.
    Bulletin of mathematical biology, 2002, Volume: 64, Issue:2

    Topics: 4-Butyrolactone; Burns; Homoserine; Humans; Models, Biological; Numerical Analysis, Computer-Assisted; Pseudomonas aeruginosa; Pseudomonas Infections

2002
The Pseudomonas autoinducer N-(3-oxododecanoyl) homoserine lactone induces cyclooxygenase-2 and prostaglandin E2 production in human lung fibroblasts: implications for inflammation.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Sep-01, Volume: 169, Issue:5

    Topics: 4-Butyrolactone; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Fibroblasts; Homoserine; Humans; Inflammation; Isoenzymes; Lung; Membrane Proteins; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Pseudomonas aeruginosa; RNA, Messenger; Up-Regulation; Virulence

2002
Synthetic analogues of the bacterial signal (quorum sensing) molecule N-(3-oxododecanoyl)-L-homoserine lactone as immune modulators.
    Journal of medicinal chemistry, 2003, Jan-02, Volume: 46, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Cell Division; Homoserine; Humans; In Vitro Techniques; Lactones; Leukocytes, Mononuclear; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Neutrophil Activation; Pseudomonas aeruginosa; Spleen; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2003
Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment.
    Journal of bacteriology, 2003, Volume: 185, Issue:7

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Cell Division; Culture Media; Gene Expression Regulation, Bacterial; Homeodomain Proteins; Homoserine; Molecular Sequence Data; Mutation; Oligonucleotide Array Sequence Analysis; Pseudomonas aeruginosa; Regulon; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction

2003
Library screening for synthetic agonists and antagonists of a Pseudomonas aeruginosa autoinducer.
    Chemistry & biology, 2003, Volume: 10, Issue:6

    Topics: 4-Butyrolactone; Aminophenols; Bacterial Proteins; Biofilms; DNA-Binding Proteins; Drug Design; Gene Library; Genes, Reporter; Genetic Techniques; Homoserine; Lactones; Molecular Structure; Pseudomonas aeruginosa; Quinolones; Signal Transduction; Structure-Activity Relationship; Trans-Activators; Virulence Factors

2003
Modification of in vivo and in vitro T- and B-cell-mediated immune responses by the Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone.
    Infection and immunity, 2003, Volume: 71, Issue:8

    Topics: 4-Butyrolactone; Animals; B-Lymphocytes; Concanavalin A; Female; Homoserine; Immunity, Cellular; Immunization; Immunoglobulin G; In Vitro Techniques; Interferon-gamma; Interleukin-4; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Mitogens; Ovalbumin; Pseudomonas aeruginosa; RNA, Messenger; T-Lymphocytes; Th1 Cells; Th2 Cells; Virulence

2003
The Pseudomonas aeruginosa autoinducer N-3-oxododecanoyl homoserine lactone accelerates apoptosis in macrophages and neutrophils.
    Infection and immunity, 2003, Volume: 71, Issue:10

    Topics: 4-Butyrolactone; Animals; Apoptosis; Cell Line; Chemokine CCL2; Chemokine CXCL2; Chemokines; Homoserine; Humans; In Vitro Techniques; Macrophages; Mice; Mice, Inbred C57BL; Neutrophils; Pseudomonas aeruginosa; Pseudomonas Infections; U937 Cells; Virulence

2003
Production of acylated homoserine lactones by different serotypes of Vibrio anguillarum both in culture and during infection of rainbow trout.
    Systematic and applied microbiology, 2003, Volume: 26, Issue:3

    Topics: 4-Butyrolactone; Acylation; Animals; Colony Count, Microbial; Fish Diseases; Homoserine; Kidney; Liver; Macrophages; Muscles; Oncorhynchus mykiss; Respiratory Burst; Signal Transduction; Superoxides; Vibrio; Vibrio Infections

2003
Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Mar-09, Volume: 101, Issue:10

    Topics: 4-Butyrolactone; Animals; Cell Line; Cell Membrane; Cells, Cultured; CHO Cells; COS Cells; Cricetinae; Dogs; HeLa Cells; Homoserine; Humans; Immunity, Innate; Pseudomonas aeruginosa; Respiratory Mucosa; Signal Transduction; Virulence

2004
Bacterial quorum-sensing signals are inactivated by mammalian cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Mar-23, Volume: 101, Issue:12

    Topics: 4-Butyrolactone; Epithelium; Homoserine; Humans; Pseudomonas aeruginosa; Respiratory System; Signal Transduction

2004
The role of regulators in the expression of quorum-sensing signals in Pseudomonas aeruginosa.
    Journal of molecular microbiology and biotechnology, 2003, Volume: 6, Issue:2

    Topics: 4-Butyrolactone; Bacterial Proteins; Culture Media; Cyclic AMP Receptor Protein; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Homoserine; Humans; Models, Biological; Pseudomonas aeruginosa; Repressor Proteins; Signal Transduction; Trans-Activators; Transcription Factors

2003
Pseudomonas aeruginosa autoinducer enters and functions in mammalian cells.
    Journal of bacteriology, 2004, Volume: 186, Issue:8

    Topics: 4-Butyrolactone; Animals; Bacterial Proteins; Cell Nucleus; Chlorocebus aethiops; COS Cells; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Homoserine; Promoter Regions, Genetic; Pseudomonas aeruginosa; Recombinant Fusion Proteins; Signal Transduction; Trans-Activators; Transcription Factors

2004
Azithromycin inhibits MUC5AC production induced by the Pseudomonas aeruginosa autoinducer N-(3-Oxododecanoyl) homoserine lactone in NCI-H292 Cells.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:9

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Azithromycin; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Flavonoids; Homoserine; Humans; I-kappa B Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mucin 5AC; Mucins; Phosphorylation; Pseudomonas aeruginosa; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Up-Regulation

2004
Differential immune modulatory activity of Pseudomonas aeruginosa quorum-sensing signal molecules.
    Infection and immunity, 2004, Volume: 72, Issue:11

    Topics: 4-Butyrolactone; Concanavalin A; Gene Expression Regulation; Homoserine; Humans; Interleukin-2; Leukocytes, Mononuclear; Lipopolysaccharides; Lymphocyte Activation; Pseudomonas aeruginosa; Quinolones; Signal Transduction; Tumor Necrosis Factor-alpha

2004
Synthesis and stability of small molecule probes for Pseudomonas aeruginosa quorum sensing modulation.
    Organic & biomolecular chemistry, 2004, Nov-21, Volume: 2, Issue:22

    Topics: 4-Butyrolactone; Biochemistry; Cyclohexanones; Drug Evaluation, Preclinical; Fluorine; Homoserine; Hydrolysis; Isomerism; Ketones; Molecular Probes; Pseudomonas aeruginosa; Serratia; Structure-Activity Relationship

2004
A Pseudomonas aeruginosa quorum-sensing molecule influences Candida albicans morphology.
    Molecular microbiology, 2004, Volume: 54, Issue:5

    Topics: 4-Butyrolactone; Antifungal Agents; beta-Galactosidase; Candida albicans; Dodecanol; Farnesol; Gene Expression Regulation, Fungal; Genes, Bacterial; Genes, Fungal; Genes, Reporter; Homoserine; Microscopy; Mutation; Pseudomonas aeruginosa; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Fungal; RNA, Messenger; Transcription, Genetic

2004
Disruption of quorum sensing in seawater abolishes attraction of zoospores of the green alga Ulva to bacterial biofilms.
    Environmental microbiology, 2005, Volume: 7, Issue:2

    Topics: 4-Butyrolactone; Bacterial Proteins; Biofilms; Cell Adhesion; Chemotactic Factors; Diffusion; Homoserine; Hydrogen-Ion Concentration; Metalloendopeptidases; Mutation; Seawater; Temperature; Ulva; Vibrio

2005
The Pseudomonas aeruginosa quorum-sensing molecule N-3-(oxododecanoyl)-L-homoserine lactone inhibits T-cell differentiation and cytokine production by a mechanism involving an early step in T-cell activation.
    Infection and immunity, 2005, Volume: 73, Issue:3

    Topics: 4-Butyrolactone; Animals; Animals, Genetically Modified; CD4-Positive T-Lymphocytes; Cell Differentiation; Cytokines; Genes, T-Cell Receptor; Homoserine; Lymphocyte Activation; Male; Mice; Pseudomonas aeruginosa; Signal Transduction; Specific Pathogen-Free Organisms; T-Lymphocytes

2005
Novel quorum-sensing-controlled genes in Erwinia carotovora subsp. carotovora: identification of a fungal elicitor homologue in a soft-rotting bacterium.
    Molecular plant-microbe interactions : MPMI, 2005, Volume: 18, Issue:4

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; DNA Transposable Elements; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genetic Complementation Test; Homoserine; Molecular Sequence Data; Mutagenesis; Pectobacterium carotovorum; Recombinant Fusion Proteins; Sequence Alignment; Solanum tuberosum

2005
The two-component response regulator PprB modulates quorum-sensing signal production and global gene expression in Pseudomonas aeruginosa.
    Molecular microbiology, 2005, Volume: 56, Issue:5

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; DNA Transposable Elements; Gene Expression Regulation, Bacterial; Genes, Reporter; Homoserine; Ligases; Molecular Sequence Data; Movement; Mutagenesis, Insertional; Oligonucleotide Array Sequence Analysis; Pseudomonas aeruginosa; Sequence Alignment; Signal Transduction; Trans-Activators; Transcription Factors; Virulence Factors

2005
Enhancement of 5-fluorouracil sensitivity by an rTS signaling mimic in H630 colon cancer cells.
    Cancer research, 2005, Jul-01, Volume: 65, Issue:13

    Topics: 4-Butyrolactone; Antineoplastic Combined Chemotherapy Protocols; Biomimetic Materials; Cell Line, Tumor; Colonic Neoplasms; Down-Regulation; Drug Synergism; Fluorouracil; Homoserine; Humans; Isoenzymes; Phosphorylation; Protein Isoforms; RNA, Antisense; Signal Transduction; Thymidylate Synthase; Tubulin

2005
Modelling antibiotic- and anti-quorum sensing treatment of a spatially-structured Pseudomonas aeruginosa population.
    Journal of mathematical biology, 2005, Volume: 51, Issue:5

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Biofilms; Homoserine; Humans; Mathematics; Models, Biological; Pseudomonas aeruginosa; Signal Transduction; Virulence

2005
The Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone stimulates phagocytic activity in human macrophages through the p38 MAPK pathway.
    Microbes and infection, 2005, Volume: 7, Issue:15

    Topics: 4-Butyrolactone; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Homoserine; Humans; Immunoblotting; Immunologic Factors; Macrophages; Mitogen-Activated Protein Kinase 1; p38 Mitogen-Activated Protein Kinases; Phagocytosis; Pseudomonas aeruginosa; Reactive Oxygen Species; Signal Transduction; Time Factors

2005
N-Acylhomoserine lactone quorum-sensing molecules are modified and degraded by Rhodococcus erythropolis W2 by both amidolytic and novel oxidoreductase activities.
    Microbiology (Reading, England), 2005, Volume: 151, Issue:Pt 10

    Topics: 4-Butyrolactone; Amidohydrolases; Dansyl Compounds; Gene Expression Regulation, Bacterial; Homoserine; Hydrogen-Ion Concentration; Oxidoreductases; Rhodococcus; Signal Transduction; Temperature

2005
Alleviation of insulitis and moderation of diabetes in NOD mice following treatment with a synthetic Pseudomonas aeruginosa signal molecule, N-(3-oxododecanoyl)-L-homoserine lactone.
    Acta diabetologica, 2005, Volume: 42, Issue:3

    Topics: 4-Butyrolactone; Adjuvants, Immunologic; Animals; Diabetes Mellitus; Dimethyl Sulfoxide; Disease Models, Animal; Homoserine; Inflammation; Islets of Langerhans; Mice; Mice, Inbred NOD; Pancreatic Diseases; Pseudomonas aeruginosa

2005
N-acylhomoserine lactones antagonize virulence gene expression and quorum sensing in Staphylococcus aureus.
    Infection and immunity, 2006, Volume: 74, Issue:2

    Topics: 4-Butyrolactone; Bacterial Proteins; Cell Membrane; Down-Regulation; Exotoxins; Gene Expression Regulation, Bacterial; Homoserine; Pseudomonas aeruginosa; Signal Transduction; Staphylococcus aureus; Trans-Activators; Virulence

2006
Quorum sensing and the lifestyle of Yersinia.
    Current issues in molecular biology, 2006, Volume: 8, Issue:1

    Topics: 4-Butyrolactone; Bacterial Proteins; Base Sequence; Cell Movement; Gene Expression Regulation, Bacterial; Homoserine; Molecular Sequence Data; Repressor Proteins; Signal Transduction; Trans-Activators; Transcription Factors; Yersinia

2006
Synthesis of Pseudomonas quorum-sensing autoinducer analogs and structural entities required for induction of apoptosis in macrophages.
    Bioorganic & medicinal chemistry letters, 2006, Apr-15, Volume: 16, Issue:8

    Topics: 4-Butyrolactone; Apoptosis; Cells, Cultured; Homoserine; Hydrophobic and Hydrophilic Interactions; Macrophages; Pseudomonas; Structure-Activity Relationship

2006
Cooperation of two distinct ExpR regulators controls quorum sensing specificity and virulence in the plant pathogen Erwinia carotovora.
    Molecular microbiology, 2006, Volume: 60, Issue:6

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Cell Wall; Cellulase; Gene Expression Regulation, Bacterial; Homoserine; Molecular Sequence Data; Pectobacterium carotovorum; Phenotype; Plant Diseases; Plant Proteins; Repressor Proteins; RNA-Binding Proteins; Signal Transduction; Virulence

2006
PtxR modulates the expression of QS-controlled virulence factors in the Pseudomonas aeruginosa strain PAO1.
    Molecular microbiology, 2006, Volume: 61, Issue:3

    Topics: 4-Butyrolactone; Bacterial Proteins; Gene Expression Regulation, Bacterial; Glycolipids; Homoserine; Metalloendopeptidases; Mutation; Operon; Pseudomonas aeruginosa; Pyocyanine; Quinolones; Transcription Factors; Virulence Factors

2006
The quorum-sensing molecule N-3-oxododecanoyl homoserine lactone (3OC12-HSL) enhances the host defence by activating human polymorphonuclear neutrophils (PMN).
    Analytical and bioanalytical chemistry, 2007, Volume: 387, Issue:2

    Topics: 4-Butyrolactone; Bacteria; Biofilms; Cell Communication; Cells, Cultured; Chemotaxis, Leukocyte; Homoserine; Humans; Immunity; Neutrophil Activation; Phagocytosis; Pseudomonas aeruginosa; Quorum Sensing; Receptors, Immunologic; Up-Regulation

2007
Pseudomonas aeruginosa autoinducer modulates host cell responses through calcium signalling.
    Cellular microbiology, 2006, Volume: 8, Issue:10

    Topics: 4-Butyrolactone; Animals; Apoptosis; Calcium Signaling; Cytosol; Endoplasmic Reticulum; Endothelial Cells; Fibroblasts; Flow Cytometry; Homoserine; Humans; Inflammation; Inositol 1,4,5-Trisphosphate Receptors; Mice; NIH 3T3 Cells; Pseudomonas aeruginosa; Reverse Transcriptase Polymerase Chain Reaction; Virulence Factors

2006
Induction of neutrophil chemotaxis by the quorum-sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone.
    Infection and immunity, 2006, Volume: 74, Issue:10

    Topics: 4-Butyrolactone; Biofilms; Chemotaxis, Leukocyte; Homoserine; Humans; Neutrophils; Pseudomonas aeruginosa; Signal Transduction

2006
Immunization with 3-oxododecanoyl-L-homoserine lactone-protein conjugate protects mice from lethal Pseudomonas aeruginosa lung infection.
    Journal of medical microbiology, 2006, Volume: 55, Issue:Pt 10

    Topics: 4-Butyrolactone; Animals; Antibodies, Bacterial; Apoptosis; Cell Line; Colony Count, Microbial; Homoserine; Immune Sera; Injections, Subcutaneous; Lung; Macrophages; Mice; Mice, Inbred BALB C; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Serum Albumin, Bovine; Tumor Necrosis Factor-alpha; Vaccination; Vaccines, Conjugate; Vaccines, Synthetic

2006
A structurally unrelated mimic of a Pseudomonas aeruginosa acyl-homoserine lactone quorum-sensing signal.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Nov-07, Volume: 103, Issue:45

    Topics: 4-Butyrolactone; Bacterial Proteins; DNA-Binding Proteins; Escherichia coli; Homoserine; Models, Molecular; Molecular Mimicry; Molecular Structure; Pseudomonas aeruginosa; Quorum Sensing; Repressor Proteins; Signal Transduction; Trans-Activators

2006
Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia.
    American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 292, Issue:4

    Topics: 4-Butyrolactone; Animals; Aryldialkylphosphatase; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Epithelial Cells; Homoserine; Humans; Mice; Mice, Knockout; Pseudomonas aeruginosa; Quorum Sensing; Trachea

2007
Use of quantitative real-time RT-PCR to analyse the expression of some quorum-sensing regulated genes in Pseudomonas aeruginosa.
    Analytical and bioanalytical chemistry, 2007, Volume: 387, Issue:2

    Topics: 4-Butyrolactone; Biofilms; Gene Expression Regulation, Bacterial; Homoserine; Pseudomonas aeruginosa; Quorum Sensing; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2007
Pseudomonas aeruginosa quorum sensing molecule N-(3 oxododecanoyl)-l-homoserine lactone disrupts epithelial barrier integrity of Caco-2 cells.
    FEBS letters, 2006, Dec-22, Volume: 580, Issue:30

    Topics: 4-Butyrolactone; Actins; Caco-2 Cells; Cell Adhesion; Cell Proliferation; Dextrans; Electric Impedance; Enzyme Activation; Epithelial Cells; Homoserine; Humans; Membrane Proteins; Microscopy, Electron, Scanning; Mitogen-Activated Protein Kinases; Occludin; Phosphoproteins; Protein Kinase Inhibitors; Pseudomonas aeruginosa; Quorum Sensing; Zonula Occludens-1 Protein

2006
Inhibition of quorum sensing in Pseudomonas aeruginosa by N-acyl cyclopentylamides.
    Applied and environmental microbiology, 2007, Volume: 73, Issue:10

    Topics: 4-Butyrolactone; Adaptation, Physiological; Anti-Bacterial Agents; beta-Galactosidase; Biofilms; Cyclopentanes; Genes, Reporter; Glycolipids; Homoserine; Pancreatic Elastase; Pseudomonas aeruginosa; Pyocyanine; Quorum Sensing; Virulence Factors

2007
Autoinducer production and quorum-sensing dependent phenotypes of Pseudomonas aeruginosa vary according to isolation site during colonization of intubated patients.
    BMC microbiology, 2007, Apr-18, Volume: 7

    Topics: Adaptation, Physiological; Bacterial Adhesion; Biofilms; DNA, Bacterial; Equipment and Supplies; Genotype; Homoserine; Humans; Intubation, Intratracheal; Lactones; Pancreatic Elastase; Phenotype; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Statistics as Topic; Trachea

2007
Peroxisome proliferator-activated receptors mediate host cell proinflammatory responses to Pseudomonas aeruginosa autoinducer.
    Journal of bacteriology, 2008, Volume: 190, Issue:13

    Topics: Animals; Blotting, Western; Cell Line, Tumor; Cytokines; DNA; Electrophoretic Mobility Shift Assay; Homoserine; Humans; Inflammation Mediators; Lactones; Mice; NIH 3T3 Cells; Peroxisome Proliferator-Activated Receptors; PPAR gamma; PPAR-beta; Protein Binding; Pseudomonas aeruginosa; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones; Transcription, Genetic

2008
The quorum quenching antibody RS2-1G9 protects macrophages from the cytotoxic effects of the Pseudomonas aeruginosa quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone.
    Molecular immunology, 2008, Volume: 45, Issue:9

    Topics: 4-Butyrolactone; Animals; Antibodies, Monoclonal; Cell Line; Cells, Cultured; Enzyme Activation; Haptens; Homoserine; Macrophages; Mice; p38 Mitogen-Activated Protein Kinases; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Pseudomonas aeruginosa; Quorum Sensing

2008
Dominant role of paraoxonases in inactivation of the Pseudomonas aeruginosa quorum-sensing signal N-(3-oxododecanoyl)-L-homoserine lactone.
    Infection and immunity, 2008, Volume: 76, Issue:6

    Topics: 4-Butyrolactone; Animals; Aryldialkylphosphatase; Edetic Acid; Esterases; Gene Expression Regulation, Bacterial; Homoserine; Humans; Hydrolysis; Liver; Lung; Metals; Mice; Mice, Inbred ICR; Pseudomonas aeruginosa; Quorum Sensing

2008
Significant immunomodulatory effects of Pseudomonas aeruginosa quorum-sensing signal molecules: possible link in human sepsis.
    Clinical science (London, England : 1979), 2008, Volume: 115, Issue:11

    Topics: 4-Butyrolactone; Apoptosis; B7-2 Antigen; Bacterial Proteins; Cells, Cultured; Coculture Techniques; Cytokines; Dendritic Cells; Homoserine; Humans; Immune Tolerance; Lymphocyte Activation; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Sepsis; T-Lymphocyte Subsets; Th2 Cells

2008
The Pseudomonas aeruginosa autoinducer dodecanoyl-homoserine lactone inhibits the putrescine synthesis in human cells.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2008, Volume: 116, Issue:5

    Topics: Amino Acid Sequence; Animals; Cell Division; Cell Line; Cell Proliferation; Growth Inhibitors; Homoserine; Humans; Lactones; Molecular Sequence Data; Ornithine Decarboxylase; Pseudomonas aeruginosa; Putrescine; Quorum Sensing

2008
Pseudomonas aeruginosa quorum-sensing signal molecules induce IL-8 production by human corneal epithelial cells.
    Eye & contact lens, 2008, Volume: 34, Issue:3

    Topics: 4-Butyrolactone; Bacterial Proteins; Cell Line; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Homoserine; Humans; Interleukin-8; Pseudomonas aeruginosa; Quorum Sensing; Signal Transduction

2008
Bacterial quorum sensing: a new target for anti-infective immunotherapy.
    Expert opinion on biological therapy, 2008, Volume: 8, Issue:6

    Topics: 4-Butyrolactone; Animals; Anti-Bacterial Agents; Antibodies, Bacterial; Antibodies, Monoclonal; Antibody Specificity; Bacteria; Bacterial Infections; Bacterial Proteins; Bacterial Vaccines; Drug Design; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Homoserine; Humans; Immunization, Passive; Immunotherapy; Immunotherapy, Active; Peptides, Cyclic; Quorum Sensing; Virulence

2008
Modulation of gene expression via disruption of NF-kappaB signaling by a bacterial small molecule.
    Science (New York, N.Y.), 2008, Jul-11, Volume: 321, Issue:5886

    Topics: 4-Butyrolactone; Adult; Animals; Cyclic AMP Response Element-Binding Protein; Cystic Fibrosis; Female; Gene Expression Regulation; Homoserine; Humans; I-kappa B Kinase; I-kappa B Proteins; Immunity, Innate; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Pseudomonas aeruginosa; Pseudomonas Infections; Signal Transduction; Toll-Like Receptors; Transcription Factor RelA

2008
A bacterial small molecule undermining immune response signaling.
    Chembiochem : a European journal of chemical biology, 2008, Nov-03, Volume: 9, Issue:16

    Topics: 4-Butyrolactone; Gene Expression Regulation; Homoserine; Humans; Immunity, Innate; NF-kappa B; Pseudomonas aeruginosa; Signal Transduction

2008
The junctional integrity of epithelial cells is modulated by Pseudomonas aeruginosa quorum sensing molecule through phosphorylation-dependent mechanisms.
    Experimental cell research, 2009, Jan-15, Volume: 315, Issue:2

    Topics: 4-Butyrolactone; beta Catenin; Caco-2 Cells; Cadherins; Cytoplasm; Epithelial Cells; Genistein; Homoserine; Humans; Intercellular Junctions; Membrane Proteins; Occludin; Okadaic Acid; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Binding; Pseudomonas aeruginosa; Quorum Sensing; Staurosporine; Zonula Occludens-1 Protein

2009
Pseudomonas aeruginosa quorum-sensing signal molecules interfere with dendritic cell-induced T-cell proliferation.
    FEMS immunology and medical microbiology, 2009, Volume: 55, Issue:3

    Topics: 4-Butyrolactone; Animals; Cell Proliferation; Dendritic Cells; Homoserine; Immunologic Factors; Mice; Mice, Inbred C57BL; Pseudomonas aeruginosa; Quinolones; T-Lymphocytes

2009
Structural understanding of quorum-sensing inhibitors by molecular modeling study in Pseudomonas aeruginosa.
    Applied microbiology and biotechnology, 2009, Volume: 83, Issue:6

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Bacterial Proteins; Computer Simulation; Homoserine; Molecular Structure; Protein Binding; Pseudomonas aeruginosa; Quorum Sensing; Trans-Activators

2009
Influence of Pseudomonas aeruginosa quorum sensing signal molecule N-(3-oxododecanoyl) homoserine lactone on mast cells.
    Medical microbiology and immunology, 2009, Volume: 198, Issue:2

    Topics: 4-Butyrolactone; Animals; Apoptosis; Calcium; Cell Degranulation; Cell Line; Cell Proliferation; Cell Survival; Histamine; Homoserine; Interleukin-6; Mast Cells; Mice; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Virulence

2009
Pseudomonas aeruginosa Las quorum sensing autoinducer suppresses growth and biofilm production in Legionella species.
    Microbiology (Reading, England), 2009, Volume: 155, Issue:Pt 6

    Topics: 4-Butyrolactone; Biofilms; Genes, Bacterial; Homoserine; Legionella pneumophila; Pseudomonas aeruginosa; Quorum Sensing; Reverse Transcriptase Polymerase Chain Reaction; RNA, Bacterial; Virulence; Virulence Factors; Water Microbiology

2009
Microbial quorum-sensing molecules induce acrosome loss and cell death in human spermatozoa.
    Infection and immunity, 2009, Volume: 77, Issue:11

    Topics: 4-Butyrolactone; Acrosome; Apoptosis; Candida albicans; Cell Membrane; Cells, Cultured; Dendritic Cells; DNA Fragmentation; Farnesol; Flow Cytometry; Homoserine; Humans; Infertility, Male; Male; Microscopy, Fluorescence; Necrosis; Pseudomonas aeruginosa; Quorum Sensing; Sperm Motility; Spermatozoa

2009
Quorum-quenching acylase reduces the virulence of Pseudomonas aeruginosa in a Caenorhabditis elegans infection model.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Amidohydrolases; Animals; Caenorhabditis elegans; Disease Models, Animal; Homoserine; Hydrogen Cyanide; Pseudomonas aeruginosa; Quorum Sensing; Virulence

2009
Role of PvdQ in Pseudomonas aeruginosa virulence under iron-limiting conditions.
    Microbiology (Reading, England), 2010, Volume: 156, Issue:Pt 1

    Topics: 4-Butyrolactone; Amidohydrolases; Animals; Bacterial Proteins; Biofilms; Caenorhabditis elegans; Gene Deletion; Gene Expression Regulation, Bacterial; Homoserine; Iron; Oligopeptides; Pseudomonas aeruginosa; Solanum tuberosum; Virulence

2010
Anti-Clostridium difficile potential of tetramic acid derivatives from Pseudomonas aeruginosa quorum-sensing autoinducers.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2

    Topics: Anti-Bacterial Agents; Clostridioides difficile; Homoserine; Lactones; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Pyrrolidinones; Quorum Sensing

2010
Paraoxonase 2 is down-regulated by the Pseudomonas aeruginosa quorumsensing signal N-(3-oxododecanoyl)-L-homoserine lactone and attenuates oxidative stress induced by pyocyanin.
    The Biochemical journal, 2010, Jan-27, Volume: 426, Issue:1

    Topics: 4-Butyrolactone; Aryldialkylphosphatase; Biological Transport; Blotting, Western; Calcimycin; Calcium; Cell Line; Cell Survival; Down-Regulation; Enzyme Activation; Homoserine; Humans; Oxidative Stress; Pseudomonas aeruginosa; Pyocyanine; Quorum Sensing; RNA, Small Interfering; Virulence

2010
Pseudomonas signal molecule 3-oxo-C12-homoserine lactone interferes with binding of rosiglitazone to human PPARgamma.
    Microbes and infection, 2010, Volume: 12, Issue:3

    Topics: 4-Butyrolactone; Anti-Inflammatory Agents; Homoserine; Humans; PPAR gamma; Protein Binding; Pseudomonas aeruginosa; Rosiglitazone; Thiazolidinediones

2010
Biofilm-induced modifications in the proteome of Pseudomonas aeruginosa planktonic cells.
    Biochimica et biophysica acta, 2010, Volume: 1804, Issue:4

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; 4-Butyrolactone; Alcohol Oxidoreductases; Bacterial Proteins; Biofilms; Bioreactors; Gene Expression; Homoserine; Oxidative Stress; Plankton; Proteome; Pseudomonas aeruginosa; Quorum Sensing

2010
Dynamic regulation of N-acyl-homoserine lactone production and degradation in Pseudomonas putida IsoF.
    FEMS microbiology ecology, 2010, Volume: 72, Issue:1

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Chromatography, Liquid; Feedback, Physiological; Homoserine; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Models, Biological; Pseudomonas putida; Quorum Sensing; Sequence Analysis, DNA

2010
Analysis of quorum sensing-dependent virulence factor production and its relationship with antimicrobial susceptibility in Pseudomonas aeruginosa respiratory isolates.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2010, Volume: 16, Issue:12

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Bacterial Proteins; Biofilms; Drug Resistance, Multiple, Bacterial; Endopeptidases; Gene Expression Regulation, Bacterial; Homoserine; Humans; Ligases; Metalloendopeptidases; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections; Pyocyanine; Quorum Sensing; Respiratory Tract Infections; Signal Transduction; Trans-Activators; Transcription Factors; Virulence Factors

2010
Pseudomonas aeruginosa pvdQ gene prevents Caco-2 cells from obstruction of quorum-sensing signal.
    Current microbiology, 2011, Volume: 62, Issue:1

    Topics: 4-Butyrolactone; Apoptosis; Bacterial Proteins; Caco-2 Cells; Epithelial Cells; Homoserine; Humans; Pseudomonas aeruginosa; Quorum Sensing

2011
Human transcriptome analysis reveals a potential role for active transport in the metabolism of Pseudomonas aeruginosa autoinducers.
    Microbes and infection, 2010, Volume: 12, Issue:12-13

    Topics: 4-Butyrolactone; Animals; Biological Transport, Active; Cells, Cultured; Cytoplasm; Epithelial Cells; Gene Expression Profiling; Homoserine; Humans; Metabolic Networks and Pathways; Mice; Microarray Analysis; Pseudomonas aeruginosa; Time Factors; Up-Regulation

2010
The plant pathogen Pseudomonas fuscovaginae contains two conserved quorum sensing systems involved in virulence and negatively regulated by RsaL and the novel regulator RsaM.
    Environmental microbiology, 2011, Volume: 13, Issue:1

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Cloning, Molecular; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Homoserine; Molecular Sequence Data; Mutation; Oryza; Plant Diseases; Pseudomonas; Quorum Sensing; Repressor Proteins; Substrate Specificity; Virulence

2011
Functional properties of synthetic N-acyl-L-homoserine lactone analogs of quorum-sensing gram-negative bacteria on the growth of human oral squamous carcinoma cells.
    Investigational new drugs, 2012, Volume: 30, Issue:1

    Topics: Acyl-Butyrolactones; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Homoserine; Humans; Inhibitory Concentration 50; Lactones; Molecular Structure; Mouth Neoplasms; Pseudomonas aeruginosa; Quorum Sensing; Radiation-Sensitizing Agents; Structure-Activity Relationship; Time Factors

2012
Determination of acyl homoserine lactone and tetramic acid concentrations in biological samples.
    Methods in molecular biology (Clifton, N.J.), 2011, Volume: 692

    Topics: 4-Butyrolactone; Biofilms; Chemical Fractionation; Chromatography, Liquid; Dimerization; Homoserine; Mass Spectrometry; Microscopy, Confocal; Pseudomonas aeruginosa; Reproducibility of Results

2011
Modulation of mammalian cell processes by bacterial quorum sensing molecules.
    Methods in molecular biology (Clifton, N.J.), 2011, Volume: 692

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Apoptosis; Bacteria; Blotting, Western; Cell Line; Homoserine; Humans; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Poly(ADP-ribose) Polymerases; Protein Kinase C-delta; Quorum Sensing; Signal Transduction

2011
Alveolar epithelium protects macrophages from quorum sensing-induced cytotoxicity in a three-dimensional co-culture model.
    Cellular microbiology, 2011, Volume: 13, Issue:3

    Topics: 4-Butyrolactone; Coculture Techniques; Epithelial Cells; Flow Cytometry; Homoserine; Humans; Intercellular Adhesion Molecule-1; Lung; Macrophages; Microscopy, Confocal; Pseudomonas aeruginosa; Pulmonary Alveoli; Quorum Sensing; Respiratory Mucosa; Signal Transduction; U937 Cells

2011
Controlling the contents of microdroplets by exploiting the permeability of PDMS.
    Lab on a chip, 2011, Mar-21, Volume: 11, Issue:6

    Topics: 4-Butyrolactone; Crystallization; Dimethylpolysiloxanes; Escherichia coli; Green Fluorescent Proteins; Homoserine; Microfluidic Analytical Techniques; Microscopy, Fluorescence; Permeability; Quorum Sensing

2011
The Pseudomonas aeruginosa autoinducer 3O-C12 homoserine lactone provokes hyperinflammatory responses from cystic fibrosis airway epithelial cells.
    PloS one, 2011, Jan-31, Volume: 6, Issue:1

    Topics: 4-Butyrolactone; Calcium; Cystic Fibrosis; Cytokines; Epithelial Cells; Homoserine; Humans; Inflammation; Lactones; Pseudomonas aeruginosa; Respiratory System

2011
Electrochemical detection of quorum sensing signaling molecules by dual signal confirmation at microelectrode arrays.
    Analytical chemistry, 2011, Mar-15, Volume: 83, Issue:6

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Agrobacterium tumefaciens; Aminophenols; beta-Galactosidase; Biomimetic Materials; Biosensing Techniques; Culture Media, Conditioned; Electrochemistry; Galactosides; Gold; Homoserine; Hydrolysis; Limit of Detection; Microelectrodes; Pseudomonas aeruginosa; Quorum Sensing; Saliva; Time Factors

2011
A multitask biosensor for micro-volumetric detection of N-3-oxo-dodecanoyl-homoserine lactone quorum sensing signal.
    Biosensors & bioelectronics, 2011, Apr-15, Volume: 26, Issue:8

    Topics: 4-Butyrolactone; Biosensing Techniques; Cystic Fibrosis; High-Throughput Screening Assays; Homoserine; Humans; Pseudomonas aeruginosa; Quorum Sensing; Sputum

2011
PA0305 of Pseudomonas aeruginosa is a quorum quenching acylhomoserine lactone acylase belonging to the Ntn hydrolase superfamily.
    Microbiology (Reading, England), 2011, Volume: 157, Issue:Pt 7

    Topics: 4-Butyrolactone; Amidohydrolases; Animals; Caenorhabditis elegans; Carboxylic Ester Hydrolases; Cloning, Molecular; DNA Transposable Elements; Gene Expression Regulation, Bacterial; Genome, Bacterial; Homoserine; Lactones; Penicillin Amidase; Protein Processing, Post-Translational; Pseudomonas aeruginosa; Quorum Sensing; Sequence Deletion; Virulence Factors

2011
Anti-activator QslA defines the quorum sensing threshold and response in Pseudomonas aeruginosa.
    Molecular microbiology, 2011, Volume: 80, Issue:4

    Topics: Acyl-Butyrolactones; Bacterial Proteins; Blotting, Western; Gene Expression Regulation, Bacterial; Homoserine; Immunoprecipitation; Lactones; Promoter Regions, Genetic; Protein Binding; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Signal Transduction; Trans-Activators; Virulence Factors

2011
The Pseudomonas aeruginosa quorum-sensing signal N-(3-oxododecanoyl) homoserine lactone can accelerate cutaneous wound healing through myofibroblast differentiation in rats.
    FEMS immunology and medical microbiology, 2011, Volume: 62, Issue:2

    Topics: 4-Butyrolactone; Animals; Cell Differentiation; Cells, Cultured; Cyclooxygenase 2; Disease Models, Animal; Gene Expression; Histocytochemistry; Homoserine; Inflammation; Male; Myofibroblasts; Neutrophils; Pseudomonas aeruginosa; Rats; Rats, Sprague-Dawley; Up-Regulation; Wound Healing; Wounds and Injuries

2011
Immunosuppressive but non-LasR-inducing analogues of the Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)-l-homoserine lactone.
    Journal of medicinal chemistry, 2011, May-12, Volume: 54, Issue:9

    Topics: 4-Butyrolactone; Animals; Aza Compounds; Bacterial Proteins; Cell Proliferation; Homoserine; Humans; Immunosuppressive Agents; Jurkat Cells; Leukocytes; Luminescent Measurements; Mice; Pseudomonas aeruginosa; Quorum Sensing; Structure-Activity Relationship; Trans-Activators

2011
Roles of Pseudomonas aeruginosa autoinducers and their degradation products, tetramic acids, in bacterial survival and behavior in ecological niches.
    Microbes and environments, 2011, Volume: 26, Issue:2

    Topics: Acyl-Butyrolactones; Anti-Bacterial Agents; Disinfectants; Escherichia coli; Homoserine; Klebsiella pneumoniae; Lactones; Microbial Viability; Molecular Structure; Pseudomonas aeruginosa; Pyrrolidinones; Quorum Sensing; Structure-Activity Relationship

2011
Immunomodulatory and protective roles of quorum-sensing signaling molecules N-acyl homoserine lactones during infection of mice with Aeromonas hydrophila.
    Infection and immunity, 2011, Volume: 79, Issue:7

    Topics: Acyl-Butyrolactones; Aeromonas hydrophila; Animals; Bacterial Load; Blood Cell Count; Chemokines; Cytokines; Gram-Negative Bacterial Infections; Homoserine; Immunity, Innate; Immunomodulation; Lactones; Macrophages; Mice; Neutrophils; Phagocytosis; Quorum Sensing; Signal Transduction; Thrombocytopenia

2011
The flavanone naringenin reduces the production of quorum sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1.
    Microbiology (Reading, England), 2011, Volume: 157, Issue:Pt 7

    Topics: 4-Butyrolactone; Bacterial Proteins; Combretum; Flavanones; Flavonoids; Gene Expression Regulation, Bacterial; Homoserine; Ligases; Pancreatic Elastase; Plant Preparations; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pyocyanine; Quorum Sensing; Sequence Deletion; Transcription Factors; Virulence Factors

2011
OdDHL inhibits T cell subset differentiation and delays diabetes onset in NOD mice.
    Clinical and vaccine immunology : CVI, 2011, Volume: 18, Issue:8

    Topics: 4-Butyrolactone; Animals; Autoimmune Diseases; Cell Differentiation; Cell Proliferation; Diabetes Mellitus, Type 1; Homoserine; Immunologic Factors; Mice; Mice, Inbred NOD; Pseudomonas aeruginosa; T-Lymphocyte Subsets

2011
Multiplexing and demultiplexing logic functions for computing signal processing tasks in synthetic biology.
    Biotechnology journal, 2011, Volume: 6, Issue:7

    Topics: Computer Simulation; DNA; Electronics; Escherichia coli; Gene Regulatory Networks; Homoserine; Lactones; Logic; Models, Genetic; Quorum Sensing; Repressor Proteins; Reproducibility of Results; Signal Processing, Computer-Assisted; Synthetic Biology; Trans-Activators

2011
Paraoxonase-2 modulates stress response of endothelial cells to oxidized phospholipids and a bacterial quorum-sensing molecule.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:11

    Topics: 4-Butyrolactone; Aorta; Apoptosis; Aryldialkylphosphatase; Cells, Cultured; Endothelium, Vascular; Gene Expression Regulation; Homoserine; Humans; Lipoproteins, LDL; Oxidation-Reduction; Phospholipids; Quorum Sensing; RNA, Small Interfering; Stress, Physiological

2011
Engineering microbes to sense and eradicate Pseudomonas aeruginosa, a human pathogen.
    Molecular systems biology, 2011, Aug-16, Volume: 7

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Antibiosis; Bacterial Proteins; Biofilms; Biosensing Techniques; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Reporter; Green Fluorescent Proteins; Homoserine; Humans; Organisms, Genetically Modified; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections; Pyocins; Quorum Sensing; Recombinant Fusion Proteins; Synthetic Biology

2011
Microbial spy games and host response: roles of a Pseudomonas aeruginosa small molecule in communication with other species.
    PLoS pathogens, 2011, Volume: 7, Issue:11

    Topics: 4-Butyrolactone; Candida albicans; Homoserine; Host-Pathogen Interactions; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Staphylococcus aureus

2011
Pseudomonas aeruginosa biofilm-associated homoserine lactone C12 rapidly activates apoptosis in airway epithelia.
    Cellular microbiology, 2012, Volume: 14, Issue:5

    Topics: 4-Butyrolactone; Apoptosis; Biofilms; Cell Line; Endoplasmic Reticulum; Epithelial Cells; Homoserine; Humans; Mitochondrial Membranes; Pseudomonas aeruginosa; Time Factors

2012
2,5-Piperazinedione inhibits quorum sensing-dependent factor production in Pseudomonas aeruginosa PAO1.
    Journal of basic microbiology, 2012, Volume: 52, Issue:6

    Topics: 4-Butyrolactone; Animals; Bacterial Proteins; Caenorhabditis elegans; Homoserine; Piperazines; Pseudomonas aeruginosa; Pyocyanine; Quorum Sensing; Repressor Proteins; Trans-Activators; Virulence Factors

2012
Bacterial quorum sensing molecule induces chemotaxis of human neutrophils via induction of p38 and leukocyte specific protein 1 (LSP1).
    Immunobiology, 2013, Volume: 218, Issue:2

    Topics: 4-Butyrolactone; Actins; Biofilms; Cells, Cultured; Chemotaxis; Homoserine; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Microfilament Proteins; Neutrophils; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pseudomonas aeruginosa; Pseudomonas Infections; Pyridines; Quorum Sensing

2013
RND type efflux pump system MexAB-OprM of Pseudomonas aeruginosa selects bacterial languages, 3-oxo-acyl-homoserine lactones, for cell-to-cell communication.
    BMC microbiology, 2012, May-10, Volume: 12

    Topics: Acyl-Butyrolactones; Artificial Gene Fusion; Bacterial Outer Membrane Proteins; Gene Deletion; Genes, Reporter; Genetic Complementation Test; Green Fluorescent Proteins; Homoserine; Lactones; Membrane Transport Proteins; Models, Biological; Pseudomonas aeruginosa; Quorum Sensing; Signal Transduction; Vibrio

2012
Regulation on expression of toll-like receptors on monocytes after stimulation with the 3-o-C12-HSL molecule from Pseudomonas aeruginosa.
    Current microbiology, 2012, Volume: 65, Issue:4

    Topics: 4-Butyrolactone; Cell Proliferation; Gene Expression Profiling; Gene Expression Regulation; Homoserine; Interleukin-12; Monocytes; Pseudomonas aeruginosa; RNA, Messenger; Toll-Like Receptors

2012
Cholinergic brush cells in the trachea mediate respiratory responses to quorum sensing molecules.
    Life sciences, 2012, Nov-27, Volume: 91, Issue:21-22

    Topics: 4-Butyrolactone; Animals; Homoserine; Host-Pathogen Interactions; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Nicotinic Antagonists; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Receptors, Nicotinic; Respiration; Respiratory Mucosa; Trachea

2012
The Pseudomonas aeruginosa quorum sensing signal molecule N-(3-oxododecanoyl) homoserine lactone enhances keratinocyte migration and induces Mmp13 gene expression in vitro.
    Biochemical and biophysical research communications, 2012, Oct-19, Volume: 427, Issue:2

    Topics: 4-Butyrolactone; Animals; Cell Culture Techniques; Cell Line; Cell Movement; Collagen Type I; Collagen Type I, alpha 1 Chain; Gene Expression; Homoserine; Keratinocytes; Matrix Metalloproteinase 13; Pseudomonas aeruginosa; Quorum Sensing; Rats; Re-Epithelialization; Signal Transduction; Transcription Factor AP-1

2012
Inhibition of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells by quorum sensing autoinducer-mimics.
    Organic & biomolecular chemistry, 2012, Nov-14, Volume: 10, Issue:42

    Topics: 4-Butyrolactone; Homoserine; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Pyocyanine; Quorum Sensing; Small Molecule Libraries; Virulence Factors

2012
The Pseudomonas aeruginosa N-acylhomoserine lactone quorum sensing molecules target IQGAP1 and modulate epithelial cell migration.
    PLoS pathogens, 2012, Volume: 8, Issue:10

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Biofilms; Caco-2 Cells; cdc42 GTP-Binding Protein; Cell Line; Cell Movement; Epithelial Cells; Homoserine; Humans; Phosphorylation; Pseudomonas aeruginosa; Quorum Sensing; rac1 GTP-Binding Protein; ras GTPase-Activating Proteins; Signal Transduction; Virulence Factors

2012
A widely conserved molecular switch controls quorum sensing and symbiosis island transfer in Mesorhizobium loti through expression of a novel antiactivator.
    Molecular microbiology, 2013, Volume: 87, Issue:1

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Conjugation, Genetic; Gene Expression Regulation, Bacterial; Gene Transfer, Horizontal; Genomic Islands; Homoserine; Lotus; Mesorhizobium; Nitrogen Fixation; Plasmids; Promoter Regions, Genetic; Quorum Sensing; RNA, Messenger; Symbiosis; Transcription Factors; Transcription, Genetic; Transcriptional Activation

2013
Immunomodulation and the quorum sensing molecule 3-oxo-C12-homoserine lactone: the importance of chemical scaffolding for probe development.
    Chemical communications (Cambridge, England), 2013, Feb-21, Volume: 49, Issue:15

    Topics: 4-Butyrolactone; Animals; Bone Marrow Cells; Endoplasmic Reticulum Stress; Homoserine; Immunomodulation; Macrophages; Mice; NF-kappa B; Oxidation-Reduction; Poly(ADP-ribose) Polymerases; Pseudomonas aeruginosa; Quorum Sensing

2013
Neutrophil-derived tumor necrosis factor-α contributes to acute wound healing promoted by N-(3-oxododecanoyl)-L-homoserine lactone from Pseudomonas aeruginosa.
    Journal of dermatological science, 2013, Volume: 70, Issue:2

    Topics: 4-Butyrolactone; Animals; Antibodies, Anti-Idiotypic; Cell Proliferation; Disease Models, Animal; Epidermis; Homoserine; Male; Neovascularization, Physiologic; Neutrophils; Pseudomonas aeruginosa; Pseudomonas Infections; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Wound Healing

2013
Intra-species bacterial quorum sensing studied at single cell level in a double droplet trapping system.
    International journal of molecular sciences, 2013, May-21, Volume: 14, Issue:5

    Topics: 4-Butyrolactone; Bacterial Proteins; Escherichia coli; Green Fluorescent Proteins; Homoserine; Microfluidic Analytical Techniques; Microscopy, Fluorescence; Promoter Regions, Genetic; Quorum Sensing; Single-Cell Analysis; Trans-Activators; Transformation, Genetic

2013
Role of PON2 in innate immune response in an acute infection model.
    Molecular genetics and metabolism, 2013, Volume: 110, Issue:3

    Topics: 4-Butyrolactone; Animals; Antioxidants; Aryldialkylphosphatase; Homoserine; Immunity, Innate; Inflammation Mediators; Macrophages; Male; Mice; Mice, Knockout; Oxidative Stress; Phagocytosis; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Reactive Oxygen Species

2013
Tailor-made LasR agonists modulate quorum sensing in Pseudomonas aeruginosa.
    Organic & biomolecular chemistry, 2013, Nov-07, Volume: 11, Issue:41

    Topics: 4-Butyrolactone; Bacterial Proteins; Dose-Response Relationship, Drug; Homoserine; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Pseudomonas aeruginosa; Quorum Sensing; Structure-Activity Relationship; Trans-Activators

2013
Cis-2-dodecenoic acid signal modulates virulence of Pseudomonas aeruginosa through interference with quorum sensing systems and T3SS.
    BMC microbiology, 2013, Oct-18, Volume: 13

    Topics: 4-Butyrolactone; Animals; Antibiosis; Bacterial Secretion Systems; Biofilms; Burkholderia cenocepacia; Disease Models, Animal; Epithelial Cells; Fatty Acids, Monounsaturated; Gene Expression Profiling; HeLa Cells; Homoserine; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones; Quorum Sensing; Signal Transduction; Virulence; Virulence Factors; Zebrafish

2013
Role of Pseudomonas aeruginosa quorum sensing (QS) molecules on the viability and cytokine profile of human mesenchymal stem cells.
    Virulence, 2014, Feb-15, Volume: 5, Issue:2

    Topics: 4-Butyrolactone; 4-Quinolones; Apoptosis; Cell Survival; Cells, Cultured; Cytokines; Flow Cytometry; Homoserine; Humans; Mesenchymal Stem Cells; Pseudomonas aeruginosa; Quorum Sensing

2014
Interkingdom signaling and its consequences for human health.
    Virulence, 2014, Feb-15, Volume: 5, Issue:2

    Topics: 4-Butyrolactone; 4-Quinolones; Apoptosis; Cytokines; Homoserine; Humans; Mesenchymal Stem Cells; Pseudomonas aeruginosa; Quorum Sensing

2014
Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases.
    American journal of physiology. Gastrointestinal and liver physiology, 2014, Jun-01, Volume: 306, Issue:11

    Topics: Acyl-Butyrolactones; Caco-2 Cells; Enzyme Activation; Epithelial Cells; Gene Expression Regulation; Homoserine; Humans; Intestinal Mucosa; Lactones; MARVEL Domain Containing 2 Protein; Matrix Metalloproteinases; Membrane Microdomains; Occludin; Permeability; Tight Junction Proteins

2014
Mucin 3 is involved in intestinal epithelial cell apoptosis via N-(3-oxododecanoyl)-L-homoserine lactone-induced suppression of Akt phosphorylation.
    American journal of physiology. Cell physiology, 2014, Jul-15, Volume: 307, Issue:2

    Topics: 4-Butyrolactone; Apoptosis; Caco-2 Cells; Caspase 3; Epithelial Cells; Gene Expression Regulation; Homoserine; Humans; Intestinal Mucosa; Mucin-3; Phosphorylation; Proto-Oncogene Proteins c-akt

2014
Cellular effects of bacterial N-3-Oxo-dodecanoyl-L-Homoserine lactone on the sponge Suberites domuncula (Olivi, 1792): insights into an intimate inter-kingdom dialogue.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: 4-Butyrolactone; Animals; Apoptosis; Bacteria; Endocytosis; Gene Expression Regulation; Homoserine; Immunity, Innate; Membrane Proteins; Porifera; RNA, Messenger; Symbiosis

2014
Pantoea sp. isolated from tropical fresh water exhibiting N-acyl homoserine lactone production.
    TheScientificWorldJournal, 2014, Volume: 2014

    Topics: 4-Butyrolactone; Base Sequence; Chromobacterium; Escherichia coli; Fresh Water; Homoserine; Malaysia; Molecular Sequence Data; Pantoea; Quorum Sensing; RNA, Ribosomal, 16S; Sequence Analysis, RNA; Sequence Homology; Tandem Mass Spectrometry; Tropical Climate

2014
Regulation of Pseudomonas aeruginosa virulence factors by two novel RNA thermometers.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Oct-28, Volume: 111, Issue:43

    Topics: 5' Untranslated Regions; Bacterial Proteins; Base Sequence; Gene Expression Regulation, Bacterial; Homoserine; Intracellular Space; Lactones; Molecular Sequence Data; Operon; Pseudomonas aeruginosa; Real-Time Polymerase Chain Reaction; Regulatory Sequences, Nucleic Acid; RNA, Bacterial; Temperature; Transcription, Genetic; Virulence Factors

2014
Unraveling the contributions of hydrogen-bonding interactions to the activity of native and non-native ligands in the quorum-sensing receptor LasR.
    Organic & biomolecular chemistry, 2015, Feb-07, Volume: 13, Issue:5

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Bacterial Proteins; Homoserine; Hydrogen Bonding; Ligands; Pseudomonas aeruginosa; Quorum Sensing; Trans-Activators

2015
Airway Epithelial Cell Integrity Protects from Cytotoxicity of Pseudomonas aeruginosa Quorum-Sensing Signals.
    American journal of respiratory cell and molecular biology, 2015, Volume: 53, Issue:2

    Topics: Aryldialkylphosphatase; Calcium Signaling; Cell Communication; Cell Line; Epithelial Cells; Gap Junctions; Homoserine; Host-Pathogen Interactions; Humans; Lactones; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Respiratory Mucosa

2015
Paraoxonase 2 serves a proapopotic function in mouse and human cells in response to the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-homoserine lactone.
    The Journal of biological chemistry, 2015, Mar-13, Volume: 290, Issue:11

    Topics: 4-Butyrolactone; Animals; Apoptosis; Aryldialkylphosphatase; Cells, Cultured; HEK293 Cells; Homoserine; Host-Pathogen Interactions; Humans; Mice; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing

2015
Activity of ERK regulates mucin 3 expression and is involved in undifferentiated Caco-2 cell death induced by 3-oxo-C12-homoserine lactone.
    Bioscience, biotechnology, and biochemistry, 2015, Volume: 79, Issue:6

    Topics: 4-Butyrolactone; Caco-2 Cells; Cell Death; Cell Differentiation; Enzyme Activation; Homoserine; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mucin-3; Up-Regulation

2015
Role of LuxIR Homologue AnoIR in Acinetobacter nosocomialis and the Effect of Virstatin on the Expression of anoR Gene.
    Journal of microbiology and biotechnology, 2015, Volume: 25, Issue:8

    Topics: Acinetobacter; Bacterial Proteins; Biofilms; Butyrates; DNA, Bacterial; Gene Deletion; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Genome, Bacterial; Homoserine; Lactones; Locomotion; Molecular Sequence Data; Naphthalimides; Quorum Sensing; Sequence Analysis, DNA

2015
Immunization with 3-oxododecanoyl-L-homoserine lactone-r-PcrV conjugate enhances survival of mice against lethal burn infections caused by Pseudomonas aeruginosa.
    Bosnian journal of basic medical sciences, 2015, May-25, Volume: 15, Issue:2

    Topics: 4-Butyrolactone; Animals; Antibodies, Bacterial; Antigens, Bacterial; Bacterial Toxins; Burns; Disease Models, Animal; Female; Homoserine; Immunity, Humoral; Immunization; Liver; Mice; Mice, Inbred BALB C; Pore Forming Cytotoxic Proteins; Pseudomonas aeruginosa; Pseudomonas Infections; Skin; Spleen; Survival Rate; Vaccines, Conjugate

2015
Design, synthesis and biological evaluation of 4-(alkyloxy)-6-methyl-2H-pyran-2-one derivatives as quorum sensing inhibitors.
    Bioorganic & medicinal chemistry letters, 2015, Aug-01, Volume: 25, Issue:15

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Homoserine; Humans; Molecular Docking Simulation; Pseudomonas aeruginosa; Pseudomonas Infections; Pyrones; Quorum Sensing; Structure-Activity Relationship; Trans-Activators

2015
Novel Paraoxonase 2-Dependent Mechanism Mediating the Biological Effects of the Pseudomonas aeruginosa Quorum-Sensing Molecule N-(3-Oxo-Dodecanoyl)-L-Homoserine Lactone.
    Infection and immunity, 2015, Volume: 83, Issue:9

    Topics: Aryldialkylphosphatase; Blotting, Western; Cell Line; Chromatography, High Pressure Liquid; Homoserine; Host-Parasite Interactions; Humans; Immunoprecipitation; Lactones; Microscopy, Confocal; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; RNA Interference

2015
Pseudomonas aeruginosa quorum-sensing signaling molecule N-3-oxododecanoyl homoserine lactone induces matrix metalloproteinase 9 expression via the AP1 pathway in rat fibroblasts.
    Bioscience, biotechnology, and biochemistry, 2015, Volume: 79, Issue:10

    Topics: 4-Butyrolactone; Abietanes; Animals; Cell Line; Cell Nucleus; Fibroblasts; Gene Expression Regulation; Homoserine; Matrix Metalloproteinase 9; Promoter Regions, Genetic; Protein Transport; Proto-Oncogene Proteins c-fos; Pseudomonas aeruginosa; Quorum Sensing; Rats; Signal Transduction; Transcription Factor AP-1

2015
Pseudomonas aeruginosa Quorum Sensing Molecule N-(3-Oxododecanoyl)-L-Homoserine-Lactone Induces HLA-G Expression in Human Immune Cells.
    Infection and immunity, 2015, Volume: 83, Issue:10

    Topics: 4-Butyrolactone; HLA-G Antigens; Homoserine; Humans; Interleukin-10; Monocytes; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; T-Lymphocytes; U937 Cells; Up-Regulation

2015
Promotion of acute-phase skin wound healing by Pseudomonas aeruginosa C
    International wound journal, 2016, Volume: 13, Issue:6

    Topics: 4-Butyrolactone; Acute Disease; Analysis of Variance; Animals; Biopsy, Needle; Disease Models, Animal; Female; Homoserine; Immunohistochemistry; Neutrophils; Pseudomonas aeruginosa; Random Allocation; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tumor Necrosis Factor-alpha; Wound Healing; Wounds and Injuries

2016
N-(3-oxo-acyl) homoserine lactone inhibits tumor growth independent of Bcl-2 proteins.
    Oncotarget, 2016, Feb-02, Volume: 7, Issue:5

    Topics: 4-Butyrolactone; Animals; Apoptosis; Aryldialkylphosphatase; Carcinoma, Lewis Lung; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Female; Flow Cytometry; Fluorescent Antibody Technique; Homoserine; Humans; Immunoenzyme Techniques; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Nude; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2016
Sensing developing biofilms: the bitter receptor T2R38 on myeloid cells.
    Pathogens and disease, 2016, Volume: 74, Issue:3

    Topics: 4-Butyrolactone; Biofilms; Cell Line, Tumor; Chemotaxis; HL-60 Cells; Homoserine; Humans; Lipid Droplets; Macrophages; Neutrophils; Phagocytosis; Platelet Glycoprotein GPIb-IX Complex; Quorum Sensing; Receptors, G-Protein-Coupled; U937 Cells

2016
Orthogonal intercellular signaling for programmed spatial behavior.
    Molecular systems biology, 2016, Jan-25, Volume: 12, Issue:1

    Topics: 4-Butyrolactone; Cell Communication; Homoserine; Models, Genetic; Promoter Regions, Genetic; Quorum Sensing; Signal Transduction; Systems Biology

2016
Pseudomonas aeruginosa N-3-oxo-dodecanoyl-homoserine Lactone Elicits Changes in Cell Volume, Morphology, and AQP9 Characteristics in Macrophages.
    Frontiers in cellular and infection microbiology, 2016, Volume: 6

    Topics: 4-Butyrolactone; Aquaporins; Biofilms; Cell Shape; Cell Size; Cells, Cultured; Homoserine; Host-Pathogen Interactions; Humans; Immunity, Innate; Macrophages; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; RNA, Messenger; Signal Transduction; Virulence Factors; Water

2016
Paraoxonase 2 modulates a proapoptotic function in LS174T cells in response to quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone.
    Scientific reports, 2016, 07-01, Volume: 6

    Topics: 4-Butyrolactone; Acetylcysteine; Apoptosis; Aryldialkylphosphatase; beta-Cyclodextrins; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; HCT116 Cells; Homoserine; Humans; Microscopy, Electron, Transmission; Mitochondria; Mucin-2; Quorum Sensing

2016
The effect of burdock leaf fraction on adhesion, biofilm formation, quorum sensing and virulence factors of Pseudomonas aeruginosa.
    Journal of applied microbiology, 2017, Volume: 122, Issue:3

    Topics: 4-Butyrolactone; Arctium; Biofilms; Homoserine; Pancreatic Elastase; Plant Extracts; Plant Leaves; Pseudomonas aeruginosa; Pyocyanine; Quorum Sensing; Virulence; Virulence Factors

2017
The bacterial quorum-sensing molecule, N-3-oxo-dodecanoyl-L-homoserine lactone, inhibits mediator release and chemotaxis of murine mast cells.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2017, Volume: 66, Issue:3

    Topics: 4-Butyrolactone; Animals; Apoptosis; Cells, Cultured; Chemotaxis; Homoserine; Interleukin-6; Lipopolysaccharides; Male; Mast Cells; Mice; Mice, Inbred BALB C; Passive Cutaneous Anaphylaxis; Pseudomonas aeruginosa; Quorum Sensing; Tumor Necrosis Factor-alpha

2017
Isolation of rhamnolipids-producing cultures from faeces: Influence of interspecies communication on the yield of rhamnolipid congeners.
    New biotechnology, 2017, May-25, Volume: 36

    Topics: Animals; Biotechnology; Cattle; Chickens; Enterococcus faecalis; Escherichia coli; Feces; Glycolipids; Homoserine; Lactones; Manure; Pseudomonas aeruginosa; Quorum Sensing; Surface-Active Agents; Sus scrofa

2017
Exposure of airway epithelial cells to Pseudomonas aeruginosa biofilm-derived quorum sensing molecules decrease the activity of the anti-oxidant response element bound by NRF2.
    Biochemical and biophysical research communications, 2017, 02-05, Volume: 483, Issue:2

    Topics: 4-Butyrolactone; Antioxidant Response Elements; Biofilms; Cell Line; Cystic Fibrosis; Epithelial Cells; Gene Expression Regulation; Heme Oxygenase-1; Homoserine; Humans; Interleukin-8; Lung; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing

2017
Furvina inhibits the 3-oxo-C12-HSL-based quorum sensing system of Pseudomonas aeruginosa and QS-dependent phenotypes.
    Biofouling, 2017, Volume: 33, Issue:2

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Furans; Homoserine; Microbial Sensitivity Tests; Molecular Docking Simulation; Phenotype; Pseudomonas aeruginosa; Quorum Sensing; Vinyl Compounds; Virulence Factors

2017
Characterization of the multiple molecular mechanisms underlying RsaL control of phenazine-1-carboxylic acid biosynthesis in the rhizosphere bacterium Pseudomonas aeruginosa PA1201.
    Molecular microbiology, 2017, Volume: 104, Issue:6

    Topics: 4-Butyrolactone; Bacteria; Bacterial Proteins; Gene Expression Regulation, Bacterial; Homoserine; Phenazines; Promoter Regions, Genetic; Pseudomonas aeruginosa; Quorum Sensing; Repressor Proteins; Rhizosphere

2017
Quorum sensing network in clinical strains of A. baumannii: AidA is a new quorum quenching enzyme.
    PloS one, 2017, Volume: 12, Issue:3

    Topics: 4-Butyrolactone; Acinetobacter baumannii; Bacterial Proteins; Cross Infection; Down-Regulation; Escherichia coli; Genes, Bacterial; Homoserine; Quorum Sensing

2017
Structure based virtual screening for identification of potential quorum sensing inhibitors against LasR master regulator in Pseudomonas aeruginosa.
    Microbial pathogenesis, 2017, Volume: 107

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Bacterial Proteins; Chemical Phenomena; Drug Discovery; Drug Evaluation, Preclinical; Homoserine; Hydrogen Bonding; Molecular Conformation; Molecular Docking Simulation; Pseudomonas aeruginosa; Quorum Sensing; Trans-Activators; Transcription Factors; User-Computer Interface; Virulence Factors

2017
A Pseudomonas aeruginosa Quorum-Sensing autoinducer analog enhances the activity of antibiotics against resistant strains.
    The journal of medical investigation : JMI, 2017, Volume: 64, Issue:1.2

    Topics: Animals; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Drug Synergism; Homoserine; Humans; Lactones; Mice; Mice, Inbred ICR; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Thienamycins

2017
Expression of toll-like receptors in T lymphocytes stimulated with N-(3-oxododecanoyl)-L-homoserine lactone from Pseudomonas aeruginosa.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2017, Volume: 125, Issue:6

    Topics: 4-Butyrolactone; Cell Proliferation; Cells, Cultured; Gene Expression; Homoserine; Humans; T-Lymphocytes; Toll-Like Receptors; Tumor Necrosis Factor-alpha

2017
The multi-output incoherent feedforward loop constituted by the transcriptional regulators LasR and RsaL confers robustness to a subset of quorum sensing genes in Pseudomonas aeruginosa.
    Molecular bioSystems, 2017, Jun-01, Volume: 13, Issue:6

    Topics: 4-Butyrolactone; Bacterial Proteins; Gene Expression Regulation; Homoserine; Pseudomonas aeruginosa; Quorum Sensing; Repressor Proteins; Trans-Activators

2017
Pseudomonas aeruginosa quorum-sensing response in the absence of functional LasR and LasI proteins: the case of strain 148, a virulent dolphin isolate.
    FEMS microbiology letters, 2017, 07-03, Volume: 364, Issue:12

    Topics: 4-Butyrolactone; Animals; Bacterial Proteins; Cyclic AMP Receptor Protein; Dolphins; Gene Expression Regulation, Bacterial; Glycolipids; Homoserine; Operon; Pseudomonas aeruginosa; Pyocyanine; Quorum Sensing; Trans-Activators; Transcription, Genetic; Virulence

2017
Quorum sensing molecules production by nosocomial and soil isolates Acinetobacter baumannii.
    Archives of microbiology, 2017, Volume: 199, Issue:10

    Topics: 4-Butyrolactone; Acinetobacter baumannii; Agrobacterium tumefaciens; Anti-Bacterial Agents; Biofilms; Biosensing Techniques; Chromatography, Thin Layer; Chromobacterium; Cross Infection; Homoserine; Lactones; Quorum Sensing; Soil Microbiology; Virulence Factors

2017
N-(3-oxododecanoyl)-L-homoserine lactone interactions in the breast tumor microenvironment: Implications for breast cancer viability and proliferation in vitro.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: 4-Butyrolactone; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Homoserine; Humans; Necrosis; Tumor Microenvironment

2017
Quorum-Quenching Human Designer Cells for Closed-Loop Control of Pseudomonas aeruginosa Biofilms.
    Nano letters, 2017, 08-09, Volume: 17, Issue:8

    Topics: A549 Cells; Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Cell Culture Techniques; Cell Survival; DNA; Drug Resistance, Bacterial; Genetic Vectors; HEK293 Cells; Herpes Simplex Virus Protein Vmw65; Homoserine; Humans; Lactones; Nuclear Localization Signals; Pseudomonas aeruginosa; Quorum Sensing; Recombinant Fusion Proteins; Synthetic Biology; Tobramycin; Trans-Activators; Virulence; Virulence Factors

2017
Pseudomonas aeruginosa auto inducer3-oxo-C
    Microbial pathogenesis, 2017, Volume: 110

    Topics: 4-Butyrolactone; Antibiosis; Biofilms; Homoserine; Pseudomonas aeruginosa; Staphylococcus epidermidis

2017
N-(3-Oxo-acyl)-homoserine lactone induces apoptosis primarily through a mitochondrial pathway in fibroblasts.
    Cellular microbiology, 2018, Volume: 20, Issue:1

    Topics: 4-Butyrolactone; Animals; Apoptosis; Caspase 3; Caspase 7; Caspase 9; Cell Line, Tumor; Cytochromes c; Fibroblasts; HCT116 Cells; Homoserine; Humans; Mice; Mice, Knockout; Microbial Interactions; Mitochondria; Mitochondrial Membranes; Pseudomonas aeruginosa; Quorum Sensing

2018
Assessing Pseudomonas aeruginosa Autoinducer Effects on Mammalian Epithelial Cells.
    Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1673

    Topics: Animals; Caco-2 Cells; Cell Extracts; Electric Impedance; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Fluorescence; Homoserine; Humans; Immunoblotting; Immunoprecipitation; Lactones; Mammals; Microscopy, Confocal; ras GTPase-Activating Proteins; Tight Junctions

2018
A novel screen-printed mast cell-based electrochemical sensor for detecting spoilage bacterial quorum signaling molecules (N-acyl-homoserine-lactones) in freshwater fish.
    Biosensors & bioelectronics, 2018, Apr-15, Volume: 102

    Topics: 4-Butyrolactone; Animals; Biosensing Techniques; Dielectric Spectroscopy; Fishes; Fresh Water; Graphite; Homoserine; Mast Cells; Nanotubes, Carbon; Pseudomonas aeruginosa; Quorum Sensing; Rats

2018
N-(3-oxododecanoyl)-l-homoserine-lactone, a quorum sensing molecule, affects cellular content of nonprotein thiol content in rat lymphocytes: Its relation with intracellular Zn
    Chemico-biological interactions, 2018, Jan-25, Volume: 280

    Topics: 4-Butyrolactone; Animals; Apoptosis; Cells, Cultured; Glutathione; Homoserine; Lymphocytes; Male; Oxidative Stress; Quorum Sensing; Rats; Rats, Wistar; Sulfhydryl Compounds; Thymus Gland; Zinc

2018
Hyperpolarization by N-(3-oxododecanoyl)-l-homoserine-lactone, a quorum sensing molecule, in rat thymic lymphocytes.
    Chemico-biological interactions, 2018, Mar-01, Volume: 283

    Topics: 4-Butyrolactone; Animals; Calcium; Cell Polarity; Charybdotoxin; Flow Cytometry; Glyburide; Homoserine; KATP Channels; Lymphocytes; Permeability; Potassium; Potassium Channels, Voltage-Gated; Quinine; Quorum Sensing; Rats; Rats, Wistar; Thymocytes

2018
N-(3-oxododecanoyl)-l-homoserine lactone modulates mitochondrial function and suppresses proliferation in intestinal goblet cells.
    Life sciences, 2018, May-15, Volume: 201

    Topics: 4-Butyrolactone; Adenosine Triphosphate; Apoptosis; Aryldialkylphosphatase; Calcium; Cell Proliferation; Electron Transport; Goblet Cells; Homoserine; Humans; Intestines; Mitochondria; Quorum Sensing

2018
Stochastic Turing patterns in a synthetic bacterial population.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 06-26, Volume: 115, Issue:26

    Topics: 4-Butyrolactone; Bacterial Proteins; Binding, Competitive; Computer Simulation; Diffusion; Gene Expression Regulation, Bacterial; Genes, Reporter; Homoserine; Isopropyl Thiogalactoside; Ligases; Models, Biological; Morphogenesis; Promoter Regions, Genetic; Pseudomonas aeruginosa; Quorum Sensing; Recombinant Proteins; Stochastic Processes; Trans-Activators; Transcription Factors

2018
Pseudomonas aeruginosa quorum sensing molecule N-3-oxo-dodecanoyl-l-homoserine lactone activates human platelets through intracellular calcium-mediated ROS generation.
    International journal of medical microbiology : IJMM, 2018, Volume: 308, Issue:7

    Topics: 4-Butyrolactone; Blood Platelets; Calcium; Homoserine; Humans; Inositol 1,4,5-Trisphosphate Receptors; Platelet Activation; Pseudomonas aeruginosa; Quorum Sensing; Reactive Oxygen Species; Type C Phospholipases

2018
Caspase-1-dependent mechanism mediating the harmful impacts of the quorum-sensing molecule N-(3-oxo-dodecanoyl)-l-homoserine lactone on the intestinal cells.
    Journal of cellular physiology, 2019, Volume: 234, Issue:4

    Topics: 4-Butyrolactone; Aryldialkylphosphatase; Caspase 1; Caspase 3; Cell Line; Enzyme Activation; Goblet Cells; Homoserine; Humans; Inflammation Mediators; Mucins; Oxidative Stress; Pyroptosis; Quorum Sensing; Reactive Oxygen Species; Signal Transduction

2019
Pseudomonas aeruginosa quorum-sensing metabolite induces host immune cell death through cell surface lipid domain dissolution.
    Nature microbiology, 2019, Volume: 4, Issue:1

    Topics: 4-Butyrolactone; Animals; Apoptosis; Caspase 3; Caspase 8; Cell Line; Chlorocebus aethiops; COS Cells; HeLa Cells; Homoserine; Humans; Immune Evasion; Membrane Lipids; Mice; Mice, Inbred C57BL; Mice, Knockout; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; RAW 264.7 Cells; Receptors, Tumor Necrosis Factor, Type I

2019
Mechanism underlying N-(3-oxo-dodecanoyl)-L-homoserine lactone mediated intracellular calcium mobilization in human platelets.
    Blood cells, molecules & diseases, 2019, Volume: 79

    Topics: 4-Butyrolactone; Blood Platelets; Calcium; Calcium Signaling; Homoserine; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Virulence

2019
Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxo-dodecanoyl)-L-homoserine lactone triggers mitochondrial dysfunction and apoptosis in neutrophils through calcium signaling.
    Medical microbiology and immunology, 2019, Volume: 208, Issue:6

    Topics: 4-Butyrolactone; Apoptosis; Calcium Signaling; Healthy Volunteers; Homoserine; Humans; Mitochondria; Neutrophils; Pseudomonas aeruginosa

2019
Pseudomonas aeruginosa Induced Host Epithelial Cell Mitochondrial Dysfunction.
    Scientific reports, 2019, 08-15, Volume: 9, Issue:1

    Topics: 4-Butyrolactone; Apoptosis; Bronchi; Cell Line; Cell Respiration; DNA Damage; DNA, Mitochondrial; Epithelial Cells; Homoserine; Host-Pathogen Interactions; Humans; Metformin; Mitochondria; Models, Biological; Organelle Biogenesis; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Reactive Oxygen Species; Resveratrol

2019
Removal of toluene vapor in the absence and presence of a quorum-sensing molecule in a biotrickling filter and microbial composition shift.
    Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 2020, Volume: 55, Issue:3

    Topics: 4-Butyrolactone; Air Pollutants; Bacteria; Biodegradation, Environmental; Bioreactors; Filtration; Gases; Homoserine; Microbiota; Quorum Sensing; Toluene

2020
Genetic and Biochemical Diversity for N-acylhomoserine Lactone Biosynthesis in the Plant Pathogen Pectobacterium carotovorum subsp. carotovorum.
    Microbes and environments, 2019, Dec-27, Volume: 34, Issue:4

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Amino Acid Sequence; Bacterial Proteins; Genetic Variation; Homoserine; Pectobacterium carotovorum; Phylogeny; Plant Diseases; Quorum Sensing

2019
A novel, quorum sensor-infused liposomal drug delivery system suppresses Candida albicans biofilms.
    International journal of pharmaceutics, 2020, Mar-30, Volume: 578

    Topics: 4-Butyrolactone; Antifungal Agents; Biofilms; Candida albicans; Drug Delivery Systems; Drug Liberation; Fluconazole; Homoserine; Liposomes; Pseudomonas aeruginosa; Quorum Sensing

2020
Tarragon essential oil as a source of bioactive compounds with anti-quorum sensing and anti-proteolytic activity against Pseudomonas spp. isolated from fish - in vitro, in silico and in situ approaches.
    International journal of food microbiology, 2020, Oct-16, Volume: 331

    Topics: 4-Butyrolactone; Animals; Anti-Bacterial Agents; Artemisia; Computer Simulation; Fishes; Homoserine; Oils, Volatile; Proteolysis; Pseudomonas; Quorum Sensing

2020
The impaired quorum sensing response of Pseudomonas aeruginosa MexAB-OprM efflux pump overexpressing mutants is not due to non-physiological efflux of 3-oxo-C12-HSL.
    Environmental microbiology, 2020, Volume: 22, Issue:12

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Caprylates; Drug Resistance, Bacterial; Homoserine; Membrane Transport Proteins; Pseudomonas aeruginosa; Quinolones; Quorum Sensing

2020
N-(3-oxododecanoyl)-homoserine lactone regulates osteoblast apoptosis and differentiation by mediating intracellular calcium.
    Cellular signalling, 2020, Volume: 75

    Topics: 4-Butyrolactone; Animals; Calcium; Cell Differentiation; Cell Line; Homoserine; Mice; Osteoblasts; Periodontitis; Pseudomonas aeruginosa; Quorum Sensing

2020
Influence of Pseudomonas autoinducer N-3-oxododecanoyl homoserine lactone on human corneal epithelial cells.
    Experimental biology and medicine (Maywood, N.J.), 2021, Volume: 246, Issue:4

    Topics: 4-Butyrolactone; Cell Survival; Cytokines; Epithelial Cells; Epithelium, Corneal; Homoserine; Humans; Inflammation Mediators; Interleukin-8; NF-kappa B; Pseudomonas aeruginosa; Toll-Like Receptor 2; Toll-Like Receptor 4

2021
N-(3-oxododecanoyl)-l-homoserine lactone disrupts intestinal epithelial barrier through triggering apoptosis and collapsing extracellular matrix and tight junction.
    Journal of cellular physiology, 2021, Volume: 236, Issue:8

    Topics: 4-Butyrolactone; Animals; Apoptosis; Epithelial Cells; Extracellular Matrix; Homoserine; Intestinal Mucosa; Lactones; Mice; Pseudomonas aeruginosa; Tight Junction Proteins; Tight Junctions

2021
Autoinducer N-(3-oxododecanoyl)-l-homoserine lactone induces calcium and reactive oxygen species-mediated mitochondrial damage and apoptosis in blood platelets.
    Microbial pathogenesis, 2021, Volume: 154

    Topics: 4-Butyrolactone; Apoptosis; Blood Platelets; Calcium; Homoserine; Humans; Lactones; Pseudomonas aeruginosa; Reactive Oxygen Species

2021
An innovative role for luteolin as a natural quorum sensing inhibitor in Pseudomonas aeruginosa.
    Life sciences, 2021, Jun-01, Volume: 274

    Topics: 4-Butyrolactone; Bacterial Proteins; Biofilms; Gene Expression Regulation, Bacterial; Homoserine; Humans; Luteolin; Molecular Docking Simulation; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Trans-Activators; Virulence Factors

2021
N-(3-oxododecanoyl)-homoserine lactone disrupts intestinal barrier and induces systemic inflammation through perturbing gut microbiome in mice.
    The Science of the total environment, 2021, Jul-15, Volume: 778

    Topics: 4-Butyrolactone; Animals; Gastrointestinal Microbiome; Homoserine; Inflammation; Mice; Quorum Sensing

2021
Bitter receptor TAS2R138 facilitates lipid droplet degradation in neutrophils during Pseudomonas aeruginosa infection.
    Signal transduction and targeted therapy, 2021, 06-04, Volume: 6, Issue:1

    Topics: 4-Butyrolactone; Animals; Cell Nucleus; Cytoplasm; Homoserine; Host-Pathogen Interactions; Humans; Lipid Droplets; Mice; Neutrophils; Perilipin-2; PPAR gamma; Pseudomonas aeruginosa; Pseudomonas Infections; Receptors, G-Protein-Coupled; Tongue

2021
N-3-(oxododecanoyl)-L-homoserine lactone suppresses dendritic cell maturation by upregulating the long noncoding RNA NRIR.
    Journal of biosciences, 2021, Volume: 46

    Topics: 4-Butyrolactone; Case-Control Studies; Cell Differentiation; Dendritic Cells; Homoserine; Humans; Interleukin-6; Monocytes; Pseudomonas aeruginosa; Pseudomonas Infections; RNA, Long Noncoding

2021
N-3-oxododecanoyl homoserine lactone exacerbates endothelial cell death by inducing receptor-interacting protein kinase 1-dependent apoptosis.
    American journal of physiology. Cell physiology, 2021, 10-01, Volume: 321, Issue:4

    Topics: 4-Butyrolactone; Apoptosis; Caspase 3; Caspase 8; Cells, Cultured; Enzyme Activation; Homoserine; Human Umbilical Vein Endothelial Cells; Humans; Lipopolysaccharides; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction

2021
Study of the Dynamics of Biofilm Formation and Elastase Activity of Pseudomonas aeruginosa in the Presence of Dodecanoyl-Homoserine Lactone.
    Bulletin of experimental biology and medicine, 2021, Volume: 171, Issue:6

    Topics: 4-Butyrolactone; Bacterial Load; Bacterial Proteins; Biofilms; Culture Media; Dose-Response Relationship, Drug; Homoserine; Pancreatic Elastase; Pseudomonas aeruginosa; Quorum Sensing

2021