homoserine and 4,5-dihydroxy-2,3-pentanedione

homoserine has been researched along with 4,5-dihydroxy-2,3-pentanedione in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (46.15)29.6817
2010's14 (53.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hom, LG; Janda, KD; Kaufmann, GF; Matsushita, M; McKenzie, KM; Meijler, MM; Moss, JA; Sun, C1
Daniels, R; De Keersmaecker, SC; De Vos, D; Habel, LW; Marchal, K; Metzger, K; van Boxel, N; Vanderleyden, J; Varszegi, C1
Babb, K; Riley, SP; Stevenson, B; von Lackum, K; Wattier, RL1
De Keersmaecker, SC; Sonck, K; Vanderleyden, J1
Babb, K; Bykowski, T; Riley, SP; Stevenson, B; von Lackum, K; Wattier, RL1
Bassler, BL; Blehert, DS; Campagna, SR; Egland, PG; Kolenbrander, PE; Palmer, RJ; Rickard, AH; Semmelhack, MF1
Balestrino, D; Deshayes, C; Doutheau, A; Forestier, C; Frezza, M; Gohar, M; Queneau, Y; Soulère, L1
Bassler, BL; Kim, JH; Lu, W; Miller, ST; Pelczer, I; Rabinowitz, J; Semmelhack, MF; Xavier, KB1
Bassler, BL; Campagna, SR; Guillemin, K; Rader, BA; Semmelhack, MF1
Babb, K; Bykowski, T; Riley, SP; Stevenson, B; von Lackum, K1
Pecharki, D; Petersen, FC; Scheie, AA1
Federle, MJ1
Janda, KD; Kaufmann, GF; Lowery, CA; Salzameda, NT; Sawada, D1
Bentley, WE; Roy, V; Sintim, HO; Smith, JA; Stewart, JE; Wang, J1
Ascenso, OS; Marques, JC; Maycock, CD; Santos, AR; Ventura, MR; Xavier, KB1
Lamosa, P; Marques, JC; Maycock, C; Miller, ST; Russell, C; Semmelhack, MF; Ventura, R; Xavier, KB1
Guillemin, K; Hicks, KG; Ottemann, KM; Rader, BA; Sweeney, EG; Wreden, C1
Gao, YL; Liu, HJ; Ning, SJ; Zhu, H1
Armbruster, CE; Juneau, RA; Murrah, K; Pang, B; Perez, AC; Swords, WE; Weimer, KE1
Li, M; Zhu, P1
Globisch, D; Janda, KD; Lowery, CA; McCague, KC1
Gilbert, ES; Niu, C; Osborn, jL; Pittman, KJ; Robbins, CM; Simmons, RB; Stubblefield, BA1
Cravatt, BF; Janda, KD; Kaufmann, GF; Lively, JM; Lowery, CA; Matamouros, S; Miller, SI; Niessen, S; Scolnick, J; Zhu, J1
Amir, LR; Bachtiar, BM; Bachtiar, EW; Ganin, H; Jarosz, LM; Krom, BP; Meijler, MM; Sunarto, H1
Bhedi, CD; Campagna, SR; Dearth, SP; May, AL; Pratte, Z; Prevatte, CW; Richardson, LL; Zimmer, BL1
Cai, G; Jiang, Q; Ma, R; Qiu, S; Sun, B; Sun, H; Xue, T1

Reviews

2 review(s) available for homoserine and 4,5-dihydroxy-2,3-pentanedione

ArticleYear
Autoinducer-2-based chemical communication in bacteria: complexities of interspecies signaling.
    Contributions to microbiology, 2009, Volume: 16

    Topics: Bacterial Physiological Phenomena; Homoserine; Lactones; Pentanes; Quorum Sensing; Signal Transduction

2009
Recent progresses on AI-2 bacterial quorum sensing inhibitors.
    Current medicinal chemistry, 2012, Volume: 19, Issue:2

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Proteins; Carbon-Sulfur Lyases; Carrier Proteins; Escherichia coli Proteins; Homoserine; Lactones; N-Glycosyl Hydrolases; Pentanes; Quorum Sensing

2012

Other Studies

24 other study(ies) available for homoserine and 4,5-dihydroxy-2,3-pentanedione

ArticleYear
Synthesis and biological validation of a ubiquitous quorum-sensing molecule.
    Angewandte Chemie (International ed. in English), 2004, Apr-13, Volume: 43, Issue:16

    Topics: Animals; Homoserine; Lactones; Luminescent Measurements; Pentanes; Pentanones; Stereoisomerism

2004
Chemical synthesis of (S)-4,5-dihydroxy-2,3-pentanedione, a bacterial signal molecule precursor, and validation of its activity in Salmonella typhimurium.
    The Journal of biological chemistry, 2005, May-20, Volume: 280, Issue:20

    Topics: Bacterial Proteins; Biofilms; Carbon-Sulfur Lyases; Genes, Bacterial; Genetic Complementation Test; Homoserine; Lactones; Mutation; Pentanes; Promoter Regions, Genetic; Salmonella typhimurium; Signal Transduction; Stereoisomerism

2005
Synthesis of autoinducer 2 by the lyme disease spirochete, Borrelia burgdorferi.
    Journal of bacteriology, 2005, Volume: 187, Issue:9

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Blotting, Western; Borrelia burgdorferi; Carbon-Sulfur Lyases; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Bacterial; Homocysteine; Homoserine; Lactones; Methionine; N-Glycosyl Hydrolases; Pentanes; RNA, Bacterial; RNA, Messenger; Transcription, Genetic

2005
Let LuxS speak up in AI-2 signaling.
    Trends in microbiology, 2006, Volume: 14, Issue:3

    Topics: Amino Acid Motifs; Amino Acid Sequence; Bacteria; Bacterial Proteins; Carbon-Sulfur Lyases; Gene Expression Regulation, Bacterial; Homoserine; Lactones; Molecular Sequence Data; Pentanes; S-Adenosylmethionine; Sequence Alignment

2006
Functionality of Borrelia burgdorferi LuxS: the Lyme disease spirochete produces and responds to the pheromone autoinducer-2 and lacks a complete activated-methyl cycle.
    International journal of medical microbiology : IJMM, 2006, Volume: 296 Suppl 40

    Topics: Antigens, Bacterial; Bacterial Proteins; Borrelia burgdorferi; Carbon-Sulfur Lyases; Gene Expression Regulation, Bacterial; Homoserine; Lactones; Lipoproteins; Methionine; Pentanes; Pheromones

2006
Autoinducer 2: a concentration-dependent signal for mutualistic bacterial biofilm growth.
    Molecular microbiology, 2006, Volume: 60, Issue:6

    Topics: Actinomyces; Bacterial Proteins; Biofilms; Carbon-Sulfur Lyases; Homoserine; Humans; Lactones; Mutation; Pentanes; Saliva; Streptococcus oralis

2006
Ac2-DPD, the bis-(O)-acetylated derivative of 4,5-dihydroxy-2,3-pentanedione (DPD) is a convenient stable precursor of bacterial quorum sensing autoinducer AI-2.
    Bioorganic & medicinal chemistry letters, 2007, Mar-01, Volume: 17, Issue:5

    Topics: Acetylation; Drug Stability; Homoserine; Hydrolysis; Lactones; Pentanes; Quorum Sensing; Stereoisomerism; Structure-Activity Relationship

2007
Phosphorylation and processing of the quorum-sensing molecule autoinducer-2 in enteric bacteria.
    ACS chemical biology, 2007, Feb-20, Volume: 2, Issue:2

    Topics: Adenosine Triphosphate; Enterobacteriaceae; Escherichia coli Proteins; Homoserine; Lactones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Pentanes; Phosphorylation; Quorum Sensing; Receptors, Cell Surface; Repressor Proteins

2007
The quorum-sensing molecule autoinducer 2 regulates motility and flagellar morphogenesis in Helicobacter pylori.
    Journal of bacteriology, 2007, Volume: 189, Issue:17

    Topics: Bacterial Proteins; Carbon-Sulfur Lyases; Flagella; Gene Deletion; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Helicobacter pylori; Homoserine; Lactones; Locomotion; Membrane Proteins; Morphogenesis; Pentanes; Quorum Sensing; RNA, Bacterial; RNA, Messenger; Transcription, Genetic

2007
Genetic and physiological characterization of the Borrelia burgdorferi ORF BB0374-pfs-metK-luxS operon.
    Microbiology (Reading, England), 2007, Volume: 153, Issue:Pt 7

    Topics: Bacterial Proteins; Borrelia burgdorferi; Carbon-Sulfur Lyases; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Homoserine; Methionine Adenosyltransferase; Open Reading Frames; Operon; Pentanes

2007
LuxS and expression of virulence factors in Streptococcus intermedius.
    Oral microbiology and immunology, 2008, Volume: 23, Issue:1

    Topics: Bacterial Proteins; Bacterial Toxins; Bacteriocins; Carbon-Sulfur Lyases; Down-Regulation; Gene Deletion; Gene Silencing; Hemolysis; Homoserine; Humans; Hyaluronoglucosaminidase; Lactones; Membrane Glycoproteins; Mutation; Pentanes; Reverse Transcriptase Polymerase Chain Reaction; Streptococcus intermedius; Transcription, Genetic; Virulence Factors

2008
Medicinal chemistry as a conduit for the modulation of quorum sensing.
    Journal of medicinal chemistry, 2010, Nov-11, Volume: 53, Issue:21

    Topics: Acyl-Butyrolactones; Animals; Anti-Bacterial Agents; Drug Discovery; Gram-Negative Bacteria; Gram-Positive Bacteria; Homoserine; Humans; Lactones; Molecular Structure; Pentanes; Peptides, Cyclic; Quorum Sensing; Structure-Activity Relationship

2010
Synthetic analogs tailor native AI-2 signaling across bacterial species.
    Journal of the American Chemical Society, 2010, Aug-18, Volume: 132, Issue:32

    Topics: Bacteria; Biological Transport; Ecosystem; Homoserine; Lactones; Models, Molecular; Molecular Conformation; Pentanes; Phosphorylation; Quorum Sensing

2010
An efficient synthesis of the precursor of AI-2, the signalling molecule for inter-species quorum sensing.
    Bioorganic & medicinal chemistry, 2011, Feb-01, Volume: 19, Issue:3

    Topics: Drug Contamination; Escherichia coli; Homoserine; Lactones; Pentanones; Quorum Sensing; Reproducibility of Results

2011
Processing the interspecies quorum-sensing signal autoinducer-2 (AI-2): characterization of phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerization by LsrG protein.
    The Journal of biological chemistry, 2011, May-20, Volume: 286, Issue:20

    Topics: Crystallography, X-Ray; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Homoserine; Lactones; Mixed Function Oxygenases; Operon; Pentanones; Protein Structure, Tertiary; Quorum Sensing

2011
Helicobacter pylori perceives the quorum-sensing molecule AI-2 as a chemorepellent via the chemoreceptor TlpB.
    Microbiology (Reading, England), 2011, Volume: 157, Issue:Pt 9

    Topics: Bacterial Proteins; Carbon-Sulfur Lyases; Chemotaxis; Helicobacter pylori; Homoserine; Lactones; Pentanes; Quorum Sensing; Signal Transduction

2011
The response of type 2 quorum sensing in Klebsiella pneumoniae to a fluctuating culture environment.
    DNA and cell biology, 2012, Volume: 31, Issue:4

    Topics: Bacterial Proteins; Boric Acids; Carbon-Sulfur Lyases; Culture Media; DNA Primers; Environment; Gene Expression Regulation, Bacterial; Glucose; Homoserine; Hydrogen-Ion Concentration; Klebsiella pneumoniae; Lactones; Pentanes; Quorum Sensing; Reverse Transcriptase Polymerase Chain Reaction; Vibrio

2012
RbsB (NTHI_0632) mediates quorum signal uptake in nontypeable Haemophilus influenzae strain 86-028NP.
    Molecular microbiology, 2011, Volume: 82, Issue:4

    Topics: Animals; ATP-Binding Cassette Transporters; Biofilms; Biomass; Chinchilla; Disease Models, Animal; Ear, Middle; Gene Deletion; Gene Expression Profiling; Haemophilus Infections; Haemophilus influenzae; Homoserine; Lactones; Pentanes; Quorum Sensing; Signal Transduction

2011
Uncharacterized 4,5-dihydroxy-2,3-pentanedione (DPD) molecules revealed through NMR spectroscopy: implications for a greater signaling diversity in bacterial species.
    Angewandte Chemie (International ed. in English), 2012, Apr-23, Volume: 51, Issue:17

    Topics: Bacteria; Bacterial Physiological Phenomena; Homoserine; Magnetic Resonance Spectroscopy; Pentanes; Quorum Sensing; Signal Transduction

2012
LuxS influences Escherichia coli biofilm formation through autoinducer-2-dependent and autoinducer-2-independent modalities.
    FEMS microbiology ecology, 2013, Volume: 83, Issue:3

    Topics: Bacterial Proteins; Biofilms; Carbon; Carbon-Sulfur Lyases; Escherichia coli; Fimbriae, Bacterial; Homoserine; Lactones; Pentanes; Phenotype; Uronic Acids

2013
A chemical biology approach to interrogate quorum-sensing regulated behaviors at the molecular and cellular level.
    Chemistry & biology, 2013, Jul-25, Volume: 20, Issue:7

    Topics: Bacterial Proteins; Homoserine; Lactones; Molecular Probe Techniques; Pentanones; Proteomics; Quorum Sensing; RNA, Messenger; Salmonella typhimurium

2013
AI-2 of Aggregatibacter actinomycetemcomitans inhibits Candida albicans biofilm formation.
    Frontiers in cellular and infection microbiology, 2014, Volume: 4

    Topics: Aggregatibacter actinomycetemcomitans; Antibiosis; Bacterial Adhesion; Bacterial Proteins; Biofilms; Candida albicans; Carbon-Sulfur Lyases; Gene Deletion; Homoserine; Humans; Hyphae; Lactones; Mouth; Mutation; Pentanones; Quorum Sensing

2014
Quorum sensing signal production and microbial interactions in a polymicrobial disease of corals and the coral surface mucopolysaccharide layer.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Acyl-Butyrolactones; Agrobacterium tumefaciens; Animals; Anthozoa; Chromobacterium; Coral Reefs; Cyanobacteria; Homoserine; Lactones; Microbial Consortia; Microbial Interactions; Pentanes; Polysaccharides, Bacterial; Quorum Sensing; Vibrio

2014
AI-2 quorum sensing negatively regulates rbf expression and biofilm formation in Staphylococcus aureus.
    International journal of medical microbiology : IJMM, 2017, Volume: 307, Issue:4-5

    Topics: Bacterial Proteins; beta-Galactosidase; Biofilms; Carbon-Sulfur Lyases; Gene Expression Regulation, Bacterial; Homoserine; Lactones; Pentanes; Polysaccharides, Bacterial; Promoter Regions, Genetic; Quorum Sensing; Staphylococcus aureus

2017