homoharringtonine and elliptinium

homoharringtonine has been researched along with elliptinium* in 1 studies

Other Studies

1 other study(ies) available for homoharringtonine and elliptinium

Article	Year
Responses of human bone marrow progenitor cells to fluoro-ara-AMP, homoharringtonine, and elliptinium. Investigational new drugs, 1984, Volume: 2, Issue:3 The cytotoxicity of the investigational anticancer drugs fluoro-ara-AMP, homoharringtonine, and elliptinium on normal human granulocyte-macrophage colony-forming units in culture (GM-CFU) was investigated using a bilayer soft agar system. For each drug, the dose-dependent survival curve on a semilogarithmic plot formed a straight line. The D0 were: 0.51 microgram/ml (fluoro-ara-AMP), 0.004 microgram/ml (homoharringtonine) and 0.026 microgram/ml (elliptinium). The in vitro toxicity of drugs on bone marrow progenitor cells did not correlate with the relative myelosuppressive potency observed in vivo. Topics: Alkaloids; Antineoplastic Agents; Arabinonucleotides; Cell Survival; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Ellipticines; Harringtonines; Hematopoietic Stem Cells; Homoharringtonine; Humans; In Vitro Techniques; Vidarabine Phosphate	1984

Article

Year

Responses of human bone marrow progenitor cells to fluoro-ara-AMP, homoharringtonine, and elliptinium.

Investigational new drugs, 1984, Volume: 2, Issue:3

The cytotoxicity of the investigational anticancer drugs fluoro-ara-AMP, homoharringtonine, and elliptinium on normal human granulocyte-macrophage colony-forming units in culture (GM-CFU) was investigated using a bilayer soft agar system. For each drug, the dose-dependent survival curve on a semilogarithmic plot formed a straight line. The D0 were: 0.51 microgram/ml (fluoro-ara-AMP), 0.004 microgram/ml (homoharringtonine) and 0.026 microgram/ml (elliptinium). The in vitro toxicity of drugs on bone marrow progenitor cells did not correlate with the relative myelosuppressive potency observed in vivo.

Topics: Alkaloids; Antineoplastic Agents; Arabinonucleotides; Cell Survival; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Ellipticines; Harringtonines; Hematopoietic Stem Cells; Homoharringtonine; Humans; In Vitro Techniques; Vidarabine Phosphate

1984