Page last updated: 2024-08-21

homocystine and folic acid

homocystine has been researched along with folic acid in 77 studies

Research

Studies (77)

Timeframe	Studies, this research(%)	All Research%
pre-1990	23 (29.87)	18.7374
1990's	16 (20.78)	18.2507
2000's	35 (45.45)	29.6817
2010's	3 (3.90)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chavez, E; Hafez, YS; Kratzer, FH; Vohra, P	1
Finkelstein, JD; Freeman, JM; Mudd, SH	1
Baldessarini, RJ	1
Spray, GH; Williams, DL	1
Holm, AC; Lassvik, C; Malinow, MR; Mölgaard, J; Olsson, AG; Upson, B	1
Besana, C; Capoferri, C	1
Brattström, LE; Hultberg, BL; Israelsson, B	1
Berlow, S	1
Gottlieb, LS; Hegsted, DM; Iseri, OA; Vitale, JJ	1
Clark, BR; Halpern, BC; Halpern, RM; Hardy, DN; Smith, RA	1
Sviatkina, OB; Vel'tishchev, IuE	1
Turner, B; Wilcken, B	1
Carson, NA; Ritchie, JW	1
Brandt, NJ; Hilden, M; Nilsson, IM; Schonheyder, F	1
Corcino, J; Herbert, V; Waxman, S	1
Cossins, EA; Dodd, WA	1
Gaull, GE	1
Bensch, K; Hagberg, B; Hambraeus, L	1
Carey, MC; Fennelly, JJ; FitzGerald, O	1
Carré, IJ; Carson, NA	1
Bourdel, G; Goubern, M; Hitier, Y; N'Diaye, F; Poiter de Courcy, G	1
Benevenga, NJ; Berlow, S; Smolin, LA	1
Cooper, BA; Dilling, LA; Haworth, JC; Lue-Shing, H; Rosenblatt, DS; Seargeant, LE; Surtees, RA	1
Hamano, H; Nagayama, M; Nanba, A; Shinohara, Y; Takizawa, S	1
Herzlich, BC	1
Bhopatkar-Teredesai, M; Faraci, FM; Heistad, DD; Lentz, SR; Malinow, MR; Piegors, DJ	1
Duell, PB; Hess, DL; Malinow, MR; Rajkovic, A; Upson, BM	1
Anderson, PH; Block, PC; Duell, PB; Gluckman, RA; Hess, DL; Kruger, WD; Malinow, MR; Phillipson, BE; Upson, BM	1
Loscalzo, J; Welch, GN	1
Bisping, JS; Deutsch, JC; Kolhouse, JF	1
Duran, M; Lilien, M; Poll-The, BT; Schröder, C; Van Hoeck, K	1
Ballerini, G; Capitani, S; Forini, E; Gemmati, D; Guerra, S; Moratelli, S; Previati, M; Scapoli, GL; Serino, ML	1
Cazenave, JP; Chantrel, F; Hannedouche, TP; Koehl, C; Kunz, K; Lisri, M; Moulin, B; Petitjean, P; Wiesel, ML	1
Alpert, MA	1
Burgess, ED; Hyndman, ME; Manns, BJ; Parsons, HG; Schaefer, JP; Scott-Douglas, NW	1
Mann, JI; Riddell, LJ	1
Croft, JB; Ford, ES; Giles, WH; Greenlund, KJ; Kittner, SJ	1
Duell, PB; Graf, EE; Irvin-Jones, A; Malinow, MR; Upson, BM	1
Chambless, LE; Howard, VJ; Malinow, MR; Pettigrew, LC; Spence, JD; Stampfer, M; Toole, JF	1
Arning, E; Bottiglieri, T; Cardaioli, G; Caso, V; Gallai, V; Paciaroni, M; Parnetti, L	1
Biller, BM; Hanson, G; Hayden, D; Klibanski, A; Llevadot, J; Rifai, N; Sesmilo, G	1
Baghurst, P; Couper, J; Thomas, DW; Wiltshire, E	1
Daly, BD; Jatoi, A; Kramer, G; Mason, JB	1
Malinow, MR; Toole, JF	1
Couper, JJ; Gent, R; Hirte, C; Pena, A; Thomas, DW; Wiltshire, EJ	1
Kaji, M; Kondo, I; Metoki, N; Sato, Y; Satoh, K; Yoshida, H	1
Alfthan, G; Aro, A; Saarinen, M; Schwab, U; Toppinen, L; Törrönen, A; Uusitupa, M	1
Carl, GF; Cornwell, PE; Hoffman, WH; Jonah, MH; Lightsey, AL; Passmore, GG; Truemper, EJ	1
Battaglioli, T; Cattaneo, M; Mannucci, PM; Martinelli, I; Pedotti, P	1
Bartolome, MJ; Blanco, R; Fernandez-Gonzalez, MD; Lopez-Hoyos, M; Martinez-Taboada, VM; Rodriguez-Valverde, V	1
Barron, M; Furie, KL; Kelly, PJ; Kistler, JP; Lee, H; Mandell, R; Shih, VE	1
Ballman, KV; Berger, PB; Brilakis, ES; Rozen, R	1
Hogan, K; Laxova, R; Rosenblatt, DS; Selzer, RR	1
SAUBERLICH, HE	1
Bets, D; Borger van der Burg, B; Donker, AJ; Kooy, A; Lehert, P; Ogterop, JC; Stehouwer, CD; Wulffelé, MG	1
Chang, N; Kim, HJ; Kim, JM; Lee, H	1
Spence, JD	1
BENNETT, MA	2
Samman, S	1
Avellone, G; Malaguarnera, M; Motta, M; Musumeci, S; Oreste, G; Pistone, G; Vinci, E	1
Cooper, SJ; Evans, A; Johnston, TG; Kelly, CB; McDonnell, AP; McMaster, D; Mulholland, C; Whitehead, AS	1
Allen, RH; Iemolo, F; Robertson, J; Spence, JD; Stabler, SP	1
Troen, AM	1
Alscher, DM; Benzinger, P	1
Benedict, S; Nagelkerke, N; Padmanabhan, R; Shafiullah, M	1
Barancoková, M; Blazícek, P; Dusinská, M; Kazimírová, A; Krajcovicová-Kudlácková, M; Pauková, V; Staruchová, M; Valachovicová, M; Volkovová, K; Wsólová, L	1
Blasko, I; Fischer, P; Jellinger, K; Jungwirth, S; Kemmler, G; Krampla, W; Tragl, KH; Wichart, I	1
Blair, IA; Brown, KS; Huang, Y; Lu, ZY; Whitehead, AS	1
Angelini, GD; Jeremy, JY; Shukla, N	1
Han, C; Jo, I; Jo, SA; Kim, E; Kim, J; Park, MH	1
Aydin, M; Kara, I; Kilic, G; Kucukali, CI; Orhan, N; Ozbek, Z; Ozkok, E; Sazci, A	1
Almeida, J; Corrêa, BB; da Silva, JA; dos Santos, A; Gago, J; Xavier, M	1
Herrmann, M; Herrmann, W; Obeid, R; Schlundt, J; Umanskaya, N	1
Golalipour, MJ; Qorbani, M; Sedehi, M	1
Chang, HM; Chen, CLH; Earnest, A; Hameed, S; Li, H; Tan, EK; Ting, SKS	1

Reviews

6 review(s) available for homocystine and folic acid

Article	Year
[Hereditary anomalies of methionine metabolism in children]. Pediatriia, 1972, Volume: 51, Issue:4 Topics: Age Factors; Child; Flatfoot; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Intellectual Disability; Kyphosis; Marfan Syndrome; Metabolism, Inborn Errors; Methionine; Scoliosis	1972
Aggravation or initiation of megaloblastosis by amino acids in the diet. JAMA, 1970, Oct-05, Volume: 214, Issue:1 Topics: Amino Acids; Anemia, Pernicious; Cell Nucleus; Diet; DNA; Erythrocytes; Folic Acid; Folic Acid Deficiency; Glycine; Hematologic Diseases; Homocystine; Humans; Methionine; Polycythemia; Pyridoxine; Serine; Tetrahydrofolate Dehydrogenase; Thymine; Vitamin B 12; Vitamin B 12 Deficiency	1970
Homocysteine and atherothrombosis. The New England journal of medicine, 1998, Apr-09, Volume: 338, Issue:15 Topics: Amino Acid Metabolism, Inborn Errors; Arteriosclerosis; Cardiovascular Diseases; Deficiency Diseases; Folic Acid; Homocysteine; Homocystine; Humans; Thrombosis; Vitamin B Complex	1998
Homocyst(e)ine, atherosclerosis, and thrombosis. Southern medical journal, 1999, Volume: 92, Issue:9 Topics: Adult; Aged; Arteriosclerosis; Female; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Hyperhomocysteinemia; Male; Middle Aged; Thrombosis	1999
Patients with atherosclerotic vascular disease: how low should plasma homocyst(e)ine levels go? American journal of cardiovascular drugs : drugs, devices, and other interventions, 2001, Volume: 1, Issue:2 Topics: Arteriosclerosis; Clinical Trials as Topic; Dipeptides; Folic Acid; Homocysteine; Homocystine; Humans; Pyridoxine; Risk Factors; Vitamin B 12	2001
The central nervous system in animal models of hyperhomocysteinemia. Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:7 Topics: Animals; Central Nervous System; Disease Models, Animal; Folic Acid; Folic Acid Deficiency; Homocystine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12	2005

Trials

8 trial(s) available for homocystine and folic acid

Article	Year
Reduction of plasma homocyst(e)ine levels by breakfast cereal fortified with folic acid in patients with coronary heart disease. The New England journal of medicine, 1998, Apr-09, Volume: 338, Issue:15 Topics: Aged; Aged, 80 and over; Coronary Disease; Cross-Over Studies; Double-Blind Method; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Homocystine; Humans; Male; Middle Aged; Nutrition Policy; Vitamins	1998
Increased plasma homocyst(e)ine after withdrawal of ready-to-eat breakfast cereal from the diet: prevention by breakfast cereal providing 200 microg folic acid. Journal of the American College of Nutrition, 2000, Volume: 19, Issue:4 Topics: Aged; Edible Grain; Female; Folic Acid; Food, Fortified; Heart Diseases; Homocysteine; Homocystine; Humans; Male; Middle Aged; Risk Factors; Vitamins	2000
Vitamin Intervention for Stroke Prevention (VISP) trial: rationale and design. Neuroepidemiology, 2001, Volume: 20, Issue:1 Topics: Adult; Aged; Cerebral Infarction; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Homocysteine; Homocystine; Humans; Male; Middle Aged; Pyridoxine; Risk Factors; Vitamin B 12	2001
Effects of growth hormone (GH) administration on homocyst(e)ine levels in men with GH deficiency: a randomized controlled trial. The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:4 Topics: Adult; Folic Acid; Growth Hormone; Homocysteine; Homocystine; Humans; Male; Middle Aged; Nutrition Assessment; Single-Blind Method; Thyroid Hormones; Time Factors; Vitamin B 12	2001
Hyperhomocysteinemia in Japanese patients with convalescent stage ischemic stroke: effect of combined therapy with folic acid and mecobalamine. Journal of the neurological sciences, 2002, Oct-15, Volume: 202, Issue:1-2 Topics: Aged; Chronic Disease; Drug Synergism; Drug Therapy, Combination; Female; Folic Acid; Hematinics; Homocystine; Humans; Hyperhomocysteinemia; Japan; Male; Middle Aged; Stroke; Treatment Outcome; Vitamin B 12	2002
Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. The American journal of clinical nutrition, 2002, Volume: 76, Issue:5 Topics: Adult; Betaine; Blood Pressure; Body Composition; Body Weight; Diet; Dietary Supplements; Energy Intake; Energy Metabolism; Female; Folic Acid; Homocystine; Humans; Lipoproteins; Lipotropic Agents; Male; Middle Aged; Physical Exertion	2002
Effects of short-term treatment with metformin on serum concentrations of homocysteine, folate and vitamin B12 in type 2 diabetes mellitus: a randomized, placebo-controlled trial. Journal of internal medicine, 2003, Volume: 254, Issue:5 Topics: Adult; Aged; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Female; Folic Acid; Homocystine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Vitamin B 12	2003
B vitamins and cognition in subjects with small vessel disease: A Substudy of VITATOPS, a randomized, placebo-controlled trial. Journal of the neurological sciences, 2017, 08-15, Volume: 379 Topics: Aged; Cognitive Dysfunction; Double-Blind Method; Female; Folic Acid; Homocystine; Humans; Male; Middle Aged; Neuropsychological Tests; Stroke; Vitamin B 12; Vitamin B 6; Vitamin B Complex	2017

Other Studies

63 other study(ies) available for homocystine and folic acid

Article	Year
Methionine toxicity in chicks and poults. Poultry science, 1978, Volume: 57, Issue:3 Topics: Animals; Betaine; Bone Diseases, Developmental; Chickens; Folic Acid; Glycine; Homocystine; Male; Methionine; Paralysis; Poultry Diseases; Turkeys	1978
Folate-responsive homocystinuria and "schizophrenia". A defect in methylation due to deficient 5,10-methylenetetrahydrofolate reductase activity. The New England journal of medicine, 1975, Mar-06, Volume: 292, Issue:10 Topics: Adolescent; Alcohol Oxidoreductases; Diagnosis, Differential; Female; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Methionine; Methylation; Schizophrenia; Tetrahydrofolates; Vitamin B 12	1975
Editorial: Metabolic hypotheses in schizophrenia. The New England journal of medicine, 1975, Mar-06, Volume: 292, Issue:10 Topics: Folic Acid; Homocystine; Homocystinuria; Humans; Methionine; Methylation; Psychotic Disorders; Schizophrenia	1975
The effects of dietary histidine, methionine and homocystine on vitamin B12 and folate levels in rat liver. The British journal of nutrition, 1976, Volume: 35, Issue:3 Topics: Animals; Body Weight; Female; Folic Acid; Histidine; Homocystine; Liver; Male; Methionine; Proteins; Rats; Vitamin B 12; Vitamin B 12 Deficiency	1976
Hyperhomocyst(e)inaemia: an independent risk factor for intermittent claudication. Journal of internal medicine, 1992, Volume: 231, Issue:3 Topics: Aged; Exercise Test; Folic Acid; Homocysteine; Homocystine; Humans; Intermittent Claudication; Lipids; Logistic Models; Male; Middle Aged; Risk Factors	1992
Delayed diagnosis of homocystinuria in a myopic. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1991, Volume: 229, Issue:1 Topics: Adult; Folic Acid; Homocystine; Homocystinuria; Humans; Male; Myopia; Pyridoxine	1991
Homocysteine and myocardial infarction. Atherosclerosis, 1988, Volume: 71, Issue:2-3 Topics: Cystathionine beta-Synthase; Folic Acid; Heterozygote; Homocystine; Humans; Male; Methionine; Middle Aged; Myocardial Infarction; Retrospective Studies; Risk Factors; Vitamin B 12	1988
Critical review of cobalamin-folate interrelations. Blood, 1986, Volume: 67, Issue:5 Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Alcohol Oxidoreductases; Folic Acid; Homocystine; Humans; Infant; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12	1986
Vitamin B 12 and methionine metabolism in the Buffalo rat liver and Morris 5123 hepatoma. Laboratory investigation; a journal of technical methods and pathology, 1972, Volume: 27, Issue:2 Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Fatty Liver; Folic Acid; Homocystine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nutrition Disorders; Rats; Vitamin B 12; Vitamin B 12 Deficiency	1972
The effect of replacement of methionine by homocystine on survival of malignant and normal adult mammalian cells in culture. Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:4 Topics: Animals; Breast; Carcinoma 256, Walker; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Culture Media; Female; Fibroblasts; Folic Acid; Homocystine; Humans; Leukemia L1210; Leukemia, Experimental; Leukemia, Myeloid; Liver; Male; Methionine; Mice; Prostate; Rats; Vitamin B 12	1974
Homocystinuria. Reduced folate levels during pyridoxine treatment. Archives of disease in childhood, 1973, Volume: 48, Issue:1 Topics: Child; Child, Preschool; Cystine; Erythrocytes; Female; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Infant; Male; Metabolic Diseases; Methionine; Methyltransferases; Pyridoxine	1973
Pregnancy and homocystinuria. The Journal of obstetrics and gynaecology of the British Commonwealth, 1973, Volume: 80, Issue:7 Topics: Adult; Amnion; Blood Coagulation Tests; Cell Line; Cystine; Female; Fibroblasts; Folic Acid; Homocystine; Homocystinuria; Humans; L-Serine Dehydratase; Methionine; Pregnancy; Pregnancy Complications; Pyridoxine; Vitamin B 12	1973
Investigations of coagulation and fibrinolysis in homocystinuria. Acta medica Scandinavica, 1974, Volume: 195, Issue:6 Topics: Adult; Blood Coagulation; Cystine; Diet; Factor V; Female; Fibrinogen; Fibrinolysis; Folic Acid; Homocystine; Homocystinuria; Humans; Methionine; Platelet Adhesiveness; Pyridoxine	1974
Metabolism of S-adenosylmethionine in germinating pea seeds: turnover and possible relationships between recycling of sulfur and transmethylation reactions. Archives of biochemistry and biophysics, 1969, Volume: 133, Issue:2 Topics: Biological Assay; Carbon Isotopes; Cell-Free System; Chromatography, Thin Layer; Enterococcus faecalis; Folic Acid; Homocystine; Kinetics; Methionine; Methylation; Models, Biological; Nucleosides; Sulfur; Sulfur Isotopes; Tritium	1969
Homocystinuria, vitamin B 6 , and folate: metabolic interrelationships and clinical significance. The Journal of pediatrics, 1972, Volume: 81, Issue:5 Topics: Alcohol Oxidoreductases; Cystathionine; Folic Acid; Glycine; Homocystine; Homocystinuria; Humans; L-Serine Dehydratase; Metabolic Diseases; Methionine; Methyltransferases; Pyridoxine; Tetrahydrofolates; Transferases; Vitamin B 12	1972
A case of homocystinuria with a dystonic neurological syndrome. Neuropadiatrie, 1970, Volume: 1, Issue:3 Topics: Adolescent; Cystine; Extrapyramidal Tracts; Folic Acid; Homocystine; Homocystinuria; Humans; Male; Methionine; Movement Disorders; Muscle Tonus; Muscular Diseases; Prognosis; Pyridoxine; Taurine	1970
Homocystinuria. II. Subnormal serum folate levels, increased folate clearance and effects of folic acid therapy. The American journal of medicine, 1968, Volume: 45, Issue:1 Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Female; FIGLU Test; Folic Acid; Homocystine; Homocystinuria; Humans; Intelligence; Male; Methionine; Nitrogen; Vitamin B 12	1968
Treatment of homocystinuria with pyridoxine. A preliminary study. Archives of disease in childhood, 1969, Volume: 44, Issue:235 Topics: Adolescent; Adult; Aminobutyrates; Child; Child, Preschool; Cystine; Female; Folic Acid; Folic Acid Deficiency; Homocystine; Homocystinuria; Humans; Hydro-Lyases; Infant; L-Serine Dehydratase; Male; Methionine; Pyridoxine	1969
Methionine synthesis, aminoimidazole carboxamide excretion and folate levels in pregnant rats. The Journal of nutrition, 1980, Volume: 110, Issue:3 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aminoimidazole Carboxamide; Animals; Body Weight; Diet; Female; Folic Acid; Glutamate Formimidoyltransferase; Glycine Hydroxymethyltransferase; Homocystine; Hydroxymethyl and Formyl Transferases; Imidazoles; Liver; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Pregnancy; Pregnancy, Animal; Rats; Tetrahydrofolates; Transferases	1980
The use of betaine for the treatment of homocystinuria. The Journal of pediatrics, 1981, Volume: 99, Issue:3 Topics: Administration, Oral; Adult; Betaine; Child; Female; Folic Acid; Homocystine; Homocystinuria; Humans; Male; Methionine; Pyridoxine	1981
Symptomatic and asymptomatic methylenetetrahydrofolate reductase deficiency in two adult brothers. American journal of medical genetics, 1993, Mar-01, Volume: 45, Issue:5 Topics: Adult; Betaine; Enzyme Stability; Folic Acid; Homocystine; Humans; Male; Metabolism, Inborn Errors; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Nervous System Diseases; Oxidoreductases Acting on CH-NH Group Donors; Paraparesis, Tropical Spastic	1993
[An adult case of homocystinuria probably due to methylenetetrahydrofolate-reductase deficiency--treatment with folic acid and the course of coagulation-fibrinolysis parameters]. Rinsho shinkeigaku = Clinical neurology, 1996, Volume: 36, Issue:2 Topics: Adult; Antithrombin III; Blood Coagulation; Fibrin Fibrinogen Degradation Products; Folic Acid; Homocystine; Homocystinuria; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Paraplegia; Peptide Hydrolases	1996
Plasma homocyst(e)ine, folate, vitamin B6 and coronary artery disease risk. Journal of the American College of Nutrition, 1996, Volume: 15, Issue:2 Topics: Adult; Coronary Disease; Folic Acid; Homocystine; Humans; Pyridoxine; Risk Factors	1996
Consequences of hyperhomocyst(e)inemia on vascular function in atherosclerotic monkeys. Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:11 Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arteriosclerosis; Carotid Arteries; Carotid Stenosis; Cholesterol; Collagen; Diet, Atherogenic; Enzyme Activation; Folic Acid; Homocysteine; Homocystine; Hypercholesterolemia; Leg; Macaca fascicularis; Nitroprusside; Protein C; Pyridoxine; Thrombomodulin; Vasodilation; Vasomotor System; Vitamin B 12	1997
The relationship between maternal and neonatal umbilical cord plasma homocyst(e)ine suggests a potential role for maternal homocyst(e)ine in fetal metabolism. American journal of obstetrics and gynecology, 1998, Volume: 178, Issue:2 Topics: Adult; Female; Fetal Blood; Folic Acid; Homocysteine; Homocystine; Humans; Infant, Newborn; Labor, Obstetric; Maternal-Fetal Exchange; Pregnancy; Reference Values; Umbilical Arteries; Umbilical Veins	1998
Plasma homocyst(e)ine levels and folic acid supplementation. The New England journal of medicine, 1998, Aug-13, Volume: 339, Issue:7 Topics: Erythrocytes; Folic Acid; Homocysteine; Homocystine; Humans	1998
Hyperhomocyst(e)inaemia in children with chronic renal failure. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14, Issue:2 Topics: Adolescent; Child; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Homocystine; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Postoperative Period; Severity of Illness Index	1999
Low folate levels and thermolabile methylenetetrahydrofolate reductase as primary determinant of mild hyperhomocystinemia in normal and thromboembolic subjects. Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:7 Topics: Adult; Aged; Female; Folic Acid; Genotype; Homocystine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Thromboembolism; Venous Thrombosis	1999
Cardiovascular morbidity and endothelial dysfunction in chronic haemodialysis patients: is homocyst(e)ine the missing link? Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14, Issue:8 Topics: Aged; Biomarkers; Cardiovascular Diseases; Cohort Studies; Endothelium, Vascular; Female; Folic Acid; Hematinics; Hemostasis; Homocysteine; Homocystine; Humans; Male; Middle Aged; Morbidity; Nutritional Status; Renal Dialysis; Risk Factors; Time Factors	1999
Hyperhomocyst(e)inemia and the prevalence of atherosclerotic vascular disease in patients with end-stage renal disease. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1999, Volume: 34, Issue:4 Topics: Aged; Arteriosclerosis; Coronary Artery Disease; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Odds Ratio; Renal Dialysis; Retrospective Studies; Risk Factors; Sex Factors; Vitamin B 12	1999
Hyperhomocysteinaemia: a risk factor for vascular disease. The New Zealand medical journal, 1999, Nov-26, Volume: 112, Issue:1100 Topics: Comorbidity; Dietary Supplements; Folic Acid; Homocystine; Humans; Hyperhomocysteinemia; Risk Factors; Vascular Diseases	1999
Association between total homocyst(e)ine and the likelihood for a history of acute myocardial infarction by race and ethnicity: Results from the Third National Health and Nutrition Examination Survey. American heart journal, 2000, Volume: 139, Issue:3 Topics: Age Distribution; Black People; Cholesterol; Comorbidity; Diabetes Mellitus; Educational Status; Female; Folic Acid; Homocysteine; Homocystine; Humans; Hypertension; Male; Mexico; Middle Aged; Multivariate Analysis; Myocardial Infarction; Nutrition Surveys; Odds Ratio; Prevalence; Risk Assessment; Sex Distribution; Smoking; United States; Vitamin B 12; White People	2000
Mild hyperhomocyst(e)inemia: a possible risk factor for cervical artery dissection. Stroke, 2001, Volume: 32, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiography; Carotid Artery, Internal, Dissection; Comorbidity; Disease Susceptibility; Female; Folic Acid; Genotype; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Risk Factors; Vertebral Artery Dissection; Vitamin B 12	2001
Reduced total plasma homocyst(e)ine in children and adolescents with type 1 diabetes. The Journal of pediatrics, 2001, Volume: 138, Issue:6 Topics: Adolescent; Child; Creatinine; Diabetes Mellitus, Type 1; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Homocystine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Vitamin B 12	2001
Folate status among patients with non-small cell lung cancer: a case-control study. Journal of surgical oncology, 2001, Volume: 77, Issue:4 Topics: Aged; Alcohol Drinking; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Diet; Female; Folic Acid; Homocystine; Humans; Lung Neoplasms; Male; Postoperative Period; Risk Factors; Smoking	2001
Validation of homocyst(e)ine-lowering treatment in the era of folic acid fortification of cereal grains. Arteriosclerosis, thrombosis, and vascular biology, 2002, Jun-01, Volume: 22, Issue:6 Topics: Clinical Trials as Topic; Edible Grain; Folic Acid; Food, Fortified; Homocystine; Humans; Hyperhomocysteinemia; United States	2002
Endothelial dysfunction relates to folate status in children and adolescents with type 1 diabetes. Diabetes, 2002, Volume: 51, Issue:7 Topics: Adolescent; Biomarkers; Blood Glucose; Blood Pressure; Brachial Artery; Child; Child, Preschool; Diabetes Mellitus, Type 1; Endothelium, Vascular; Folic Acid; Glycated Hemoglobin; Homocysteine; Homocystine; Humans; Nitroglycerin; Reference Values; Triglycerides; Vasodilation	2002
Diabetic ketoacidosis promotes a prothrombotic state. Endocrine research, 2003, Volume: 29, Issue:1 Topics: Adolescent; Child; Diabetic Ketoacidosis; Female; Fluid Therapy; Folic Acid; Homocystine; Humans; Male; Protein Kinase C; Protein S; Thrombosis; von Willebrand Factor	2003
Hyperhomocysteinemia in cerebral vein thrombosis. Blood, 2003, Aug-15, Volume: 102, Issue:4 Topics: Adolescent; Adult; Case-Control Studies; Child; Female; Folic Acid; Homocystine; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Risk Factors; Thrombophilia; Venous Thrombosis; Vitamin B 12	2003
Homocysteine levels in polymyalgia rheumatica and giant cell arteritis: influence of corticosteroid therapy. Rheumatology (Oxford, England), 2003, Volume: 42, Issue:9 Topics: Aged; Brain Ischemia; Drug Therapy, Combination; Female; Folic Acid; Giant Cell Arteritis; Glucocorticoids; Homocystine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Polymyalgia Rheumatica; Vitamin B 12	2003
Low vitamin B6 but not homocyst(e)ine is associated with increased risk of stroke and transient ischemic attack in the era of folic acid grain fortification. Stroke, 2003, Volume: 34, Issue:6 Topics: Case-Control Studies; Comorbidity; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Homocystine; Humans; Ischemic Attack, Transient; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxal Phosphate; Risk Assessment; Risk Factors; Serum Albumin; Stroke; United States; Vitamin B 12; Vitamin B 6	2003
Methylenetetrahydrofolate reductase (MTHFR) 677C>T and methionine synthase reductase (MTRR) 66A>G polymorphisms: association with serum homocysteine and angiographic coronary artery disease in the era of flour products fortified with folic acid. Atherosclerosis, 2003, Volume: 168, Issue:2 Topics: Adenine; Aged; Coronary Angiography; Coronary Disease; Cytosine; Female; Ferredoxin-NADP Reductase; Flour; Folic Acid; Food, Fortified; Genotype; Homocystine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Repressor Proteins; Thymine	2003
Adverse effect of nitrous oxide in a child with 5,10-methylenetetrahydrofolate reductase deficiency. The New England journal of medicine, 2003, Jul-03, Volume: 349, Issue:1 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5,10-Methylenetetrahydrofolate Reductase (FADH2); Anesthetics, Inhalation; Cells, Cultured; DNA Mutational Analysis; Fatal Outcome; Fibroblasts; Folic Acid; Genes, Recessive; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Infant; Male; Metabolism, Inborn Errors; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Nitrous Oxide; Oxidoreductases; Point Mutation; Polymorphism, Genetic; RNA	2003
Methionine, homocystine, choline, folic acid and vitamin B12 in the nutrition of the mouse. The Journal of nutrition, 1959, May-10, Volume: 68, Issue:1 Topics: Animals; Choline; Cystine; Folic Acid; Homocystine; Humans; Methionine; Mice; Nutritional Status; Vitamin B 12	1959
Effects of dietary folic acid supplementation on cerebrovascular endothelial dysfunction in rats with induced hyperhomocysteinemia. Brain research, 2004, Jan-23, Volume: 996, Issue:2 Topics: Animals; Blotting, Western; Brain; Cerebrovascular Circulation; Dietary Supplements; Endothelium, Vascular; Excitatory Amino Acid Transporter 2; Folic Acid; Hematinics; Homocystine; Hyperhomocysteinemia; Immunohistochemistry; Male; Nitric Oxide Synthase; Rats; Vascular Cell Adhesion Molecule-1	2004
Utilization of homocystine for growth in presence of vitamin B12 and folic acid. The Journal of biological chemistry, 1950, Volume: 187, Issue:2 Topics: Corrinoids; Cystine; Folic Acid; Growth; Homocystine; Humans; Vitamin B 12; Vitamin B Complex	1950
Nutrition and metabolism. Current opinion in lipidology, 2004, Volume: 15, Issue:2 Topics: Cardiovascular Diseases; Diet; Folic Acid; Homocystine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Physiological Phenomena; Polymorphism, Single Nucleotide	2004
Elevated plasma total homocysteine in centenarians. Clinical chemistry and laboratory medicine, 2004, Volume: 42, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Creatine; Female; Folic Acid; Homocystine; Humans; Male; Middle Aged; Pyridoxal Phosphate; Regression Analysis; Vitamin B 12	2004
Some observations on the role of folic acid in utilization of homocystine by the rat. Science (New York, N.Y.), 1949, Dec-02, Volume: 110, Issue:2866 Topics: Animals; Cysteine; Cystine; Folic Acid; Homocystine; Humans; Rats	1949
The MTHFR C677T polymorphism is associated with depressive episodes in patients from Northern Ireland. Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cohort Studies; Depressive Disorder; Female; Folic Acid; Gene Frequency; Genotype; Homocystine; Humans; Ireland; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12	2004
Can vitamin therapy prevent restenosis? Conflicting studies indicate the jury is still out on folate therapy after angioplasty. Health news (Waltham, Mass.), 2004, Volume: 10, Issue:11 Topics: Coronary Restenosis; Drug Combinations; Folic Acid; Homocystine; Humans; Randomized Controlled Trials as Topic; Treatment Outcome; Vitamin B 12; Vitamin B 6	2004
Vitamin B12, homocysteine and carotid plaque in the era of folic acid fortification of enriched cereal grain products. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2005, Jun-07, Volume: 172, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Carotid Stenosis; Cross-Sectional Studies; Edible Grain; Female; Folic Acid; Food, Fortified; Hematinics; Homocystine; Humans; Incidence; Male; Middle Aged; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency	2005
[Untreated homocystinuria in adulthood]. Deutsche medizinische Wochenschrift (1946), 2005, Oct-28, Volume: 130, Issue:43 Topics: Adult; Age Factors; Angina Pectoris; Betaine; Diagnosis, Differential; Drug Therapy, Combination; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Intervertebral Disc Displacement; Lens Subluxation; Male; Marfan Syndrome; Myopia; Osteoporosis; Retinal Detachment; Vitamin B 12; Vitamin B 6; Vitamin B Complex	2005
Effect of maternal exposure to homocystine on sodium valproate-induced neural tube defects in the mouse embryos. European journal of nutrition, 2006, Volume: 45, Issue:6 Topics: Abnormalities, Drug-Induced; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Fetal Growth Retardation; Folic Acid; Gestational Age; Homocysteine; Homocystine; Mice; Neural Tube Defects; Pregnancy; Random Allocation; Teratogens; Valproic Acid; Vitamin B 12	2006
The relationship between micronuclei in human lymphocytes and selected micronutrients in vegetarians and non-vegetarians. Mutation research, 2006, Dec-10, Volume: 611, Issue:1-2 Topics: Adult; Antioxidants; Ascorbic Acid; beta Carotene; Diet, Vegetarian; Female; Folic Acid; Homocystine; Humans; Lymphocytes; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Micronutrients; Middle Aged; Regression Analysis; Vitamin B 12; Vitamin E	2006
Conversion from cognitive health to mild cognitive impairment and Alzheimer's disease: prediction by plasma amyloid beta 42, medial temporal lobe atrophy and homocysteine. Neurobiology of aging, 2008, Volume: 29, Issue:1 Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Atrophy; Cognition Disorders; Cohort Studies; Disease Progression; Female; Folic Acid; Homocystine; Humans; Logistic Models; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Peptide Fragments; Predictive Value of Tests; Psychometrics; Retrospective Studies; Temporal Lobe; Vitamin B 12	2008
Quantification of intracellular homocysteine by stable isotope dilution liquid chromatography/tandem mass spectrometry. Biomedical chromatography : BMC, 2007, Volume: 21, Issue:1 Topics: Chromatography, Liquid; Folic Acid; Homocystine; Indicator Dilution Techniques; Isotope Labeling; Sensitivity and Specificity; Tandem Mass Spectrometry	2007
Interactive effects of homocysteine and copper on angiogenesis in porcine isolated saphenous vein. The Annals of thoracic surgery, 2007, Volume: 84, Issue:1 Topics: Animals; Copper; Coronary Artery Bypass; Folic Acid; Homocystine; In Vitro Techniques; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Saphenous Vein; Stents; Superoxides; Swine; Vascular Patency	2007
Plasma homocysteine is associated with the risk of mild cognitive impairment in an elderly Korean population. The Journal of nutrition, 2007, Volume: 137, Issue:9 Topics: Aged; Cognition Disorders; Female; Folic Acid; Homocystine; Humans; Korea; Male; Risk Factors; Vitamin B 12	2007
Effect of the methylenetetrahydrofolate reductase gene polymorphisms on homocysteine, folate and vitamin B12 in patients with bipolar disorder and relatives. Progress in neuro-psychopharmacology & biological psychiatry, 2008, Jul-01, Volume: 32, Issue:5 Topics: Adult; Analysis of Variance; Bipolar Disorder; Family; Female; Fluorescence Polarization Immunoassay; Folic Acid; Gene Frequency; Genotype; Homocystine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12	2008
Bipolar disorder, homocysteine and white matter hyperintensities. Bipolar disorders, 2008, Volume: 10, Issue:6 Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Brain; Female; Folic Acid; Haloperidol; Homocystine; Humans; Lithium Carbonate; Magnetic Resonance Imaging; Middle Aged; Neuropsychological Tests; Vitamin B 12	2008
Folate is related to phosphorylated neurofilament-H and P-tau (Ser396) in rat brain. Journal of neurochemistry, 2011, Volume: 117, Issue:6 Topics: Animals; Brain; Female; Folic Acid; Frontal Lobe; Homocysteine; Homocystine; Hyperhomocysteinemia; Methionine; Methylation; Neurofilament Proteins; Phosphoproteins; Phosphorylation; Protein Phosphatase 2; Rats; Rats, Wistar; tau Proteins	2011
Does maternal Helicobacter pylori infection increase the risk of occurrence of neural tube defects in newborns in Northern Iran? Neurosciences (Riyadh, Saudi Arabia), 2012, Volume: 17, Issue:3 Topics: Bacterial Proteins; Case-Control Studies; Female; Ferritins; Folic Acid; Helicobacter Infections; Homocystine; Humans; Immunoglobulin G; Infant, Newborn; Logistic Models; Male; Neural Tube Defects; Northern Ireland; Odds Ratio; Pregnancy; Prenatal Exposure Delayed Effects; Retrospective Studies; Risk Factors; Vitamin B 12; Young Adult	2012