homocysteine has been researched along with vitamin b 12 in 2675 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 127 (4.75) | 18.7374 |
| 1990's | 296 (11.07) | 18.2507 |
| 2000's | 1200 (44.86) | 29.6817 |
| 2010's | 811 (30.32) | 24.3611 |
| 2020's | 241 (9.01) | 2.80 |
| Authors | Studies |
|---|---|
| Das, KC; Herbert, V | 1 |
| Bolondi, L; Caletti, GC; Fontana, G; Ventrucci, M | 1 |
| Jacobsen, SJ; Mangum, JH; North, JA; Rao, NA | 1 |
| Kass, L; Peters, CL; Toler, LA | 1 |
| Chrin, LR; Jaffe, JJ | 1 |
| Magnati, G; Strata, A; Tirelli, F | 1 |
| Borgheresi, S; Zammarchi, E | 1 |
| Günther, E; Herrmann, H; Wehnert, M | 1 |
| Finkelstein, JD; Freeman, JM; Mudd, SH | 1 |
| Hamdy, MK; Noyes, OR | 1 |
| Hanna, LM; Taylor, RT | 1 |
| Cheng, FW; Shane, B; Stokstad, EL | 1 |
| Hieb, WF; Lu, NC; Stokstad, EL | 1 |
| Lou, W; Yao, G; Yao, SL; Yao, SS; Yao, Y | 1 |
| Banerjee, RV; González, JC; Huang, S; Matthews, RG; Sumner, JS | 1 |
| Reynolds, EH | 1 |
| McCully, KS; Tzanakakis, GN; Vezeridis, MP | 2 |
| Andersson, A; Brattström, L; Hultberg, B; Israelsson, B; Olsson, A | 1 |
| Mason, JB; Miller, JW | 1 |
| Allen, RH; Grigsby, J; Kaye, K; Kelly, JP; Lindenbaum, J; Matthews, LM; Pennypacker, LC; Stabler, SP | 1 |
| Garovic-Kocic, V; Rosenblatt, DS | 1 |
| Boers, GH; Eskes, TK; Steegers, EA; Steegers-Theunissen, RP; Thomas, CM; Trijbels, FJ | 1 |
| Andersson, A; Brattström, L; Hamfelt, A; Hultberg, B; Isaksson, A; Israelsson, B | 1 |
| Brattström, L; Hamfelt, A; Israelsson, B; Lindgren, A; Malinow, MR; Norrving, B; Upson, B | 1 |
| Allen, RH; Brass, EP; Marcell, PD; Stabler, SP | 1 |
| Hipwell, SE; Liteplo, RG; Lue-Shing, H; Rosenblatt, DS; Sillaots, S | 1 |
| Brattström, L; Hultberg, B; Israelsson, B; Lagerstedt, C; Tengborn, L | 1 |
| Olszewski, AJ | 1 |
| Bock, HG; Grix, A; Horwitz, A; Kang, SS; Wong, PW | 1 |
| Abels, J; Ermens, AA; Guttormsen, AB; Lindemans, J; Refsum, H; Rupreht, J; Spijkers, LJ; Ueland, PM | 1 |
| Baumgartner, R; Bubl, R; Kühne, T | 1 |
| McCully, KS; Olszewski, AJ; Vezeridis, MP | 1 |
| Allen, RH; Lindenbaum, J; Savage, DG; Stabler, SP | 2 |
| Stauffer, GV; Urbanowski, ML | 2 |
| McCully, KS; Vezeridis, MP | 1 |
| Liteplo, RG | 1 |
| Bialkowska, M; McCully, KS; Olszewski, AJ; Rudnicki, S; Szostak, WB | 1 |
| Boss, GR | 1 |
| Chu, RC; Hall, CA | 1 |
| Blanchflower, J; Keating, S; Kennedy, DG; Kennedy, S; McPartlin, J; Molloy, A; Rice, D; Scott, JM; Weir, DG | 1 |
| Begley, JA; Chu, RC; Hall, CA | 1 |
| Brattström, L; Hultberg, B; Israelsson, B; Lindgärde, F | 1 |
| Allen, RH; Brust, JC; Garrett, TJ; Healton, EB; Lindenbaum, J; Marcell, PD; Podell, ER; Savage, DG; Stabler, SP | 1 |
| Brattström, LE; Hultberg, BL; Israelsson, B; Jeppsson, JO | 1 |
| Cooper, BA; Erbe, RW; Rosenblatt, DS; Thomas, IT; Watkins, D | 1 |
| Hogenkamp, HP; Hrushesky, WJ; Roelofs, R; Trugman, J | 1 |
| Gawthorne, JM; Smith, RM | 1 |
| Fukui, S; Nakatani, K; Omori, H; Shimizu, S | 1 |
| Daniel, LJ; Griffiths, JM | 1 |
| Ritari, SJ; Rosales, F; Sakami, W | 1 |
| Naiki, N; Yamagata, S | 1 |
| Inukai, S; Sato, K; Shimizu, S | 1 |
| Batra, KK; Buehring, KU; Stokstad, EL | 1 |
| Hanna, ML; Hutton, JJ; Taylor, RT | 1 |
| Erbe, RW; Kamely, D; Littlefield, JW | 1 |
| Flavin, M; Savin, MA; Slaughter, C | 1 |
| Barker, HA | 1 |
| Hoffbrand, AV; Waters, AH | 1 |
| Smith, DA; Whitehouse, JM | 2 |
| Hanna, ML; Taylor, RT | 3 |
| Kadner, RJ; Liggins, GL | 1 |
| Greene, RC; Kung, HF; Spears, C; Weissbach, H; Williams, RD | 1 |
| Rüdiger, H | 2 |
| Jaenicke, L; Rüdiger, H | 2 |
| Capitolo, S; Marchioni, GF; Mariani, B | 1 |
| Rosenberg, LE | 1 |
| Foster, MA; Pattison, JR; Salem, AR | 1 |
| Hakami, N; Sagerson, RN; Scott, CR; Teng, CC | 1 |
| Birnbaum, J; Kaplan, L; White, RF | 1 |
| Stokstad, EL; Thenen, SW | 1 |
| Howell, JN; Jaenicke, L; Sauer, H | 1 |
| Sharma, DC | 1 |
| Bandini, S; Monteforte, S | 1 |
| Dillon, MJ; England, JM; Gompertz, D; Goodey, PA; Grant, DB; Hussein, HA; Linnell, JC; Matthews, DM; Mudd, SH; Newns, GH; Seakins, JW; Uhlendorf, BW; Wise, IJ | 1 |
| Taylor, RT; Weissbach, H | 8 |
| Taylor, RT; Weissbach, H; Whitfield, C | 1 |
| Hogenkamp, HP | 1 |
| Brot, N; Ertel, R; Taylor, R; Weissbach, H | 1 |
| Avadhani, NG; Mehta, BM; Rege, DV | 1 |
| Taylor, RT | 3 |
| Mahoney, MJ; Rosenberg, LE | 1 |
| Corcino, JJ; Herbert, V; Waxman, S | 1 |
| Bertilsson, L; Neujahr, HY | 1 |
| Dawes, J; Foster, MA | 1 |
| Aronovitch, J; Grossowicz, N | 1 |
| Calhoun, DH; Feary, TW | 1 |
| Azzena, D | 1 |
| Finkelstein, JD; Freeman, JM; Mudd, SH; Shih, VE; Uhlendorf, BW | 1 |
| Barness, LA; Morrow, G | 1 |
| Mangum, JH; North, JA | 2 |
| Fontaine, G | 1 |
| Mahoney, MJ; Mudd, SH; Rosenberg, LE; Uhlendorf, BW | 1 |
| Foster, MA; Guest, JR; Tejerina, G; Woods, DD | 1 |
| Cauthen, SE; Foster, MA; Woods, DD | 1 |
| Brodie, JD; Huennekens, FM; Kerwar, SS; Mangum, JH; Scrimgeour, KG | 1 |
| Spatz, R | 1 |
| Mangum, JH; Murray, BK; North, JA | 1 |
| Bonini, M | 1 |
| Brodie, JD; Burke, GT; Mangum, JH | 1 |
| Fujii, K; Fukui, S | 1 |
| Levy, H; Morrow, G; Mudd, SH | 1 |
| Hinds, KR; Mudd, SH; Uhlendorf, BW | 1 |
| Goodman, SI; Hammond, KB; Moe, PG; Mudd, SH; Uhlendorf, BW | 1 |
| Kerwar, SS; McAuslan, B; Spears, C; Weissbach, H | 1 |
| Demain, AL; White, RF | 1 |
| Sovik, O | 1 |
| Abeles, RH; Jennedy, JP; Levy, HL; Mudd, SH | 1 |
| McCully, KS | 10 |
| Milner, L; Weissbach, H | 1 |
| Daniel, LJ; Lust, G | 2 |
| Guttman, HN | 1 |
| Myasishcheva, NV; Poirier, LA; Stoner, GD; Wilson, MJ | 1 |
| Dudman, NP; Tyrrell, PA; Wilcken, B; Wilcken, DE | 1 |
| Houghton, JA; Houghton, PJ; Schmidt, C | 1 |
| Wickramasinghe, SN | 1 |
| Betts, AK; Gupta, VJ; Wilcken, DE | 1 |
| Beresford, SA; Boushey, CJ; Motulsky, AG; Omenn, GS | 1 |
| Becker, PJ; Delport, R; Potgieter, H; Ubbink, JB; van der Merwe, A; Vermaak, WJ | 1 |
| Allen, RH; Joosten, E; Lindenbaum, J; Naurath, HJ; Riezler, R; Stabler, SP | 1 |
| Blom, HJ; TePoele-Pothoff, MT; Trijbels, JM; Verrips, A; Wevers, RA | 1 |
| Malinow, MR; Stampfer, MJ | 1 |
| Hopkins, PN; Hunt, SC; James, BC; Vincent, GM; Williams, RR; Wu, J; Wu, LL | 1 |
| Allen, RH; Lindenbaum, J; Stabler, SP | 4 |
| Gräsbeck, R; Hansen, M; Lindgren, A; Nexø, E; Rasmussen, K | 1 |
| Agardh, CD; Agardh, E; Andersson, A; Hultberg, B | 1 |
| Blom, HJ; Copius Peereboom-Stegeman, JH; Deabreu, RA; Eskes, TK; Noordhoek, J; Trijbels, FJ; Vanaerts, LA | 1 |
| Gottfries, CG; Johansson, BV; Regland, B | 1 |
| Conley, MR; Kirke, PN; Lee, YJ; McPartlin, JM; Mills, JL; Scott, JM; Weir, DG | 1 |
| Blom, HJ; Boers, GH; Borm, GF; Eskes, TK; Nijhuis, JG; Steegers-Theunissen, RP; Thomas, CM | 1 |
| Dalery, K; Davignon, J; Genest, J; Latour, Y; Lussier-Cacan, S; Selhub, J | 1 |
| Belanger, AJ; Bostom, AG; D'Agostino, RB; Jacques, PF; O'Leary, DH; Rosenberg, IH; Schaefer, EJ; Selhub, J; Wilson, PW; Wolf, PA | 1 |
| Andersson, A; Fäldt, R; Gustafson, L; Hultberg, B; Nilsson, K | 1 |
| Anker, G; Lien, EA; Lønning, PE; Refsum, H; Ueland, PM | 1 |
| Berger, PB; Daly, RC; Edwards, BS; Frantz, RP; Jones, JD; Kottke, BA; McGregor, CG; Olson, LJ; Rodeheffer, RJ | 1 |
| Ubbink, JB | 1 |
| Carson, W; Chadefaux, B; Cooper, BA; Gavsie, A; Gilfix, BM; Lue-Shing, H; Rosenblatt, DS | 1 |
| Becker, PJ; Delport, R; Potgieter, HC; Ubbink, JB; van der Merwe, A; Vermaak, WJ | 1 |
| Daughtry, M; Galvez, N; Goodkin, DE; Green, R; Jacobsen, DW; Secic, M | 1 |
| Andersson, A; Brattström, L; Hultberg, B; Israelsson, B; Lindgren, A | 1 |
| Christensen, B; Guttormsen, AB; Refsum, H; Riedel, B; Schneede, J; Svardal, A; Ueland, PM | 1 |
| Henning, SM; Jacob, RA; Swendseid, ME; Wu, MM | 1 |
| Christensen, B; Fiskerstrand, T; Refsum, H; Tysnes, OB; Ueland, PM | 1 |
| Gatautis, VJ; Green, R; Jacobsen, DW; Ji, J; Otto, JM; Robinson, K; Savon, SR; Secic, M; Taylor, LM | 1 |
| Allen, RH; Kolhouse, JF; Stabler, SP | 1 |
| Begley, JA; Chu, RC; Colligan, PD; Hall, CA | 1 |
| Delport, R; Ubbink, JB; van der Merwe, A; Vermaak, WJ | 1 |
| Jacques, PF; Rosenberg, IH; Rush, D; Selhub, J; Wilson, PW | 1 |
| Drummond, JT; Matthews, RG | 2 |
| Acton, RT; Alvarez, JO; Copeland, RB; Cousins, AL; Go, RC; Lewis, CA; Macaluso, M; Pancharuniti, N; Perkins, LL; Sauberlich, HE | 1 |
| Rees, MM; Rodgers, GM | 1 |
| Drinka, P | 1 |
| Eskes, TK; Hollanders, HM; Peereboom-Stegeman, JH; Steegers, EA; Steegers-Theunissen, RP; Thomas, CM; Trijbels, FJ | 1 |
| Araki, A; Ito, H; Sako, Y | 1 |
| Criel, A; Devos, P; Goossens, W; Joosten, E; Lesaffre, E; Pelemans, W; Verhaeghe, R | 1 |
| Bergmark, C; de Faire, U; Mansoor, MA; Svardal, AM; Swedenborg, J; Ueland, PM | 1 |
| Blumenthal, RM; Drummond, JT; Huang, S; Matthews, RG | 1 |
| Becker, PJ; Ubbink, JB; van der Merwe, A; Vermaak, WJ | 1 |
| Amin, J; Flener, V; Ramos, M; Tisman, G; Vanyo, L; Vu, T | 1 |
| Eskes, TK; Smithells, RW; Steegers-Theunissen, RP | 1 |
| Bierdrager, E; Rauwerda, JA; Stehouwer, CD; van den Berg, M | 1 |
| Guttormsen, AB; Refsum, H; Schneede, J; Ueland, PM | 1 |
| Camilo, ME; Cardoso, JN; Cravo, ML; Glória, LM; Leitão, CN; Mira, FC; Nadeau, MR; Resende, MP; Selhub, J | 1 |
| Aukrust, P; Berge, RK; Frøland, SS; Müller, F; Svardal, AM; Ueland, PM | 2 |
| Adams, MJ; Dickinson, CM; Oakley, GP | 1 |
| Conley, MR; Kirke, PN; Lee, YJ; McPartlin, JM; Mills, JL; Molloy, AM; Scott, JM; Weir, DG | 1 |
| Riggs, KM; Rush, D; Spiro, A; Tucker, K | 1 |
| Abrahm, JL; Allen, RH; Berry, GT; Chin, MM; Gracely, EJ; Stabler, SP; Sumner, AE | 1 |
| Arseneau, P; Cooper, BA; Gilfix, BM; Katz, M; MacLean, LD; Rhode, BM | 1 |
| Dybkjaer, L; Lyngbak, M; Møller, J; Pedersen, AM; Rasmussen, K | 1 |
| Jacobsen, DW; Mayer, EL; Robinson, K | 1 |
| Allen, RH; Buring, JE; Gaziano, JM; Hennekens, CH; Kok, FJ; Reynolds, RD; Stabler, SP; Stampfer, MJ; Verhoef, P; Willett, WC | 1 |
| Belanger, AJ; Bostom, AG; D'Agostino, RB; Jacques, PF; O'Leary, DH; Rosenberg, IH; Rush, D; Schaefer, EJ; Selhub, J; Wilson, PW; Wolf, PA | 1 |
| Kang, SS | 1 |
| Adjalla, C; Belleville, F; Benhayoun, S; Felden, F; Gaucher, P; Gelot, MA; Gerard, P; Guéant, JL; Lambert, D; Nicolas, JP; Renkes, P | 1 |
| Kim, YI; Logan, JW; Mason, JB; Roubenoff, R | 1 |
| Bostom, AG; Chan, J; Jacques, PF; Lapane, KL; Nadeau, MR; Rosenberg, IH; Rozen, R; Selhub, J; Shemin, D; Sutherland, P; Yoburn, D | 1 |
| Graham, IM; Meleady, RA; Mulcahy, DA | 1 |
| Chan, CF; Cheng, SK; Lolin, YI; Masarei, JR; Pang, CP; Sanderson, JE; Woo, KS | 1 |
| González, JC; Matthews, RG; Peariso, K; Penner-Hahn, JE | 1 |
| Davignon, J; Genest, J; Lussier-Cacan, S; Piolot, A; Selhub, J; Xhignesse, M | 1 |
| Jacobsen, DW | 1 |
| Leeming, RJ | 1 |
| Joosten, E; Lesaffre, E; Riezler, R | 1 |
| Guttormsen, AB; Nesthus, I; Nygård, O; Refsum, H; Schneede, J; Ueland, PM; Vollset, SE | 1 |
| Bell, AH; Bottiglieri, T; Flicker, L; Ibrahim, J; McGrath, KM; Metz, J; Savoia, H; Schultz, D; Seal, E | 1 |
| Andersson, A; Brattström, L; Fäldt, R; Gustafson, L; Hultberg, B; Israelsson, B; Lindgren, A; Nilsson, K | 1 |
| Evans, AE; Gey, KF; Harmon, DL; McCrum, EE; McMaster, D; Whitehead, AS; Woodside, JV; Yarnell, JW; Young, IS | 2 |
| Arheart, K; Chaudhary, D; Dennis, V; Green, R; Gupta, A; Jacobsen, DW; Kutner, M; Mayer, EL; Robinson, K; Selhub, J; Vigo, P | 1 |
| Dennis, VW; Robinson, K | 1 |
| Azen, C; Carmel, R; Green, R; Howard, JM; Jacobsen, DW | 2 |
| Blom, HJ; den Heyer, M; Eskes, TK; Mariman, EC; Steegers-Theunissen, RP; Trijbels, FJ; van den Heuvel, LP; van der Put, NM | 1 |
| Jacques, P; Mahnken, B; Selhub, J; Tucker, KL; Wilson, PW | 1 |
| Adjalla, CE; Campeau, E; Christensen, B; Eydoux, P; Goyette, P; Gravel, RA; Leclerc, D; Rosenblatt, DS; Ross, M; Rozen, R | 1 |
| Amendt, K; Diehm, C; Hsu, E; Stammler, F; Stockinger, K | 1 |
| Adjalla, C; Belleville, F; Benhayoun, S; Felden, F; Gaucher, P; Gélot, MM; Gérard, P; Guéant, JL; Lambert, D; Nicolas, JP; Renkes, P | 1 |
| Baumgartner, RN; Garry, PJ; Koehler, KM; Pareo-Tubbeh, SL; Romero, LJ | 1 |
| Alm, B; Anderson, A; Fäldt, R; Gustafson, L; Hultberg, B; Nilsson, K; Nilsson, R; Vaara, I | 1 |
| Alpert, JE; Borus, JS; Bottiglieri, T; Fava, M; Nierenberg, AA; Rosenbaum, JF | 1 |
| Deutsch, JC; Kolhouse, JF; Ryder, JW; Santhosh-Kumar, CR | 1 |
| Crooks, R; Dudman, N; Finucane, P; Fryer, J; Guo, XW; Nair, B; Silberberg, J; Wlodarczyk, J; Xie, LJ | 1 |
| Domagała, TB; Gozdecka, H; Krzanowski, M; Libura, M; Szczeklik, A | 1 |
| Abad, LW; Dellaripa, P; Muldoon, BA; Nadeau, MR; Rosenberg, IH; Roubenoff, R; Selhub, J | 1 |
| Cheng, SW; Ting, AC; Wong, J | 1 |
| Freedberg, RS; Hess, DL; Katz, ES; Konecky, N; Kronzon, I; Leung, B; Malinow, MR; Perez, J; Rosenzweig, BP; Tunick, PA; Upson, B | 1 |
| Delva, MD | 1 |
| Bottiglieri, T | 1 |
| Andersson, A; Hultberg, B; Lindgren, A | 1 |
| Grobbee, DE; Kok, FJ; Kruyssen, DA; Refsum, H; Schouten, EG; Ueland, PM; Verhoef, P; Witteman, JC | 1 |
| Ahn, C; Aronow, WS; Schoenfeld, MR | 1 |
| Allen, RH; Buccellato, FR; Lindenbaum, J; Lorenzini, EC; Morabito, A; Scalabrino, G; Tredici, G | 1 |
| Flynn, MA; Herbert, V; Krause, G; Nolph, GB | 1 |
| Chambless, LE; Malinow, MR; Nieto, FJ; Schreiner, PJ; Shimakawa, T; Szklo, M | 1 |
| Adjalla, C; Beliah, M; Benhayoun, S; Gélot, MA; Guéant, JL; Lambert, D; Messing, B; Nicolas, JP; Thuillier, F | 1 |
| Matthews, JH | 1 |
| Goulding, CW; Matthews, RG; Postigo, D | 1 |
| Fushiki, S; Matsumoto, K; Nishizawa, Y; Terada, N; Yamamoto, T | 1 |
| Chanarin, I; Metz, J | 1 |
| Dreosti, IE; Fenech, MF; Rinaldi, JR | 1 |
| Baumgartner, RN; Garry, PJ; Koehler, KM; Liang, HC; Pareo-Tubbeh, SL; Romero, LJ | 1 |
| Catalano, PM; Malinow, MR; Rajkovic, A | 1 |
| Fluhr, K; Goulding, CW; Huang, S; Jarrett, JT; Matthews, RG | 1 |
| Eguchi, T; Fujita, N; Nomura, S; Ono, H; Sakamoto, A; Sakura, N; Ueda, H; Ueda, K | 1 |
| Födinger, M; Hörl, WH; Mannhalter, C; Müller, E; Pabinger, I; Schmid, R; Sunder-Plassmann, G; Wölfl, G | 1 |
| Boiocchi, M; Corona, G; Donada, C; Fabris, M; Toffoli, G; Viel, A; Zarrelli, A | 1 |
| Abrahamsson, L; Andersson, M; Bagby, J; Dyrehag, LE; Gottfries, CG; Regland, B | 1 |
| Fiskerstrand, T; Refsum, H; Ueland, PM | 1 |
| Refsum, H; Tonstad, S; Ueland, PM | 1 |
| Blom, HJ; De Graaf-Hess, A; Eskes, TK; Mariman, EC; Smeitink, JA; Steegers-Theunissen, RP; Thomas, CM; Trijbels, FJ; van der Put, NM | 1 |
| Bates, CJ; Cole, TJ; Finch, S; Mansoor, MA; Prentice, A; van der Pols, J | 1 |
| Bjerve, KS; Carlsen, SM; Følling, I; Grill, V; Refsum, H; Schneede, J | 1 |
| Ehrhart, LA; Majors, A; Pezacka, EH | 1 |
| Stampfer, MJ | 1 |
| Ahn, C; Aronow, WS | 3 |
| Cicchetti, G; Marín, GH; Tentoni, J | 1 |
| Herbert, V | 1 |
| Johansson, KW; Kilander, AF; Lindgren, A; Nilsson, O; Swolin, B | 1 |
| Agardh, CD; Agardh, E; Hultberg, B; Lövestam-Adrian, M | 1 |
| Choi, CY; Jarrett, JT; Matthews, RG | 1 |
| Goulding, CW; Matthews, RG | 2 |
| Bostom, AG; Dworkin, L; Jacques, PF; Nadeau, MR; Rosenberg, IH; Selhub, J; Shemin, D; Verhoef, P | 1 |
| Bhopatkar-Teredesai, M; Faraci, FM; Heistad, DD; Lentz, SR; Malinow, MR; Piegors, DJ | 1 |
| Beaulieu, AJ; Bostom, AG; Gohh, RY; Hume, AL; Jacques, PF; Nadeau, MR; Rosenberg, IH; Selhub, J | 1 |
| Becker, PJ; Delport, R; Joubert, J; Rossouw, H; Ubbink, JB; Vermaak, WJ | 1 |
| Donovan, U; Gibson, RS; Green, TJ; Houghton, LA; O'Connor, DL | 1 |
| Aakvaag, A; Aanderud, S; Ericsson, UB; Lien, EA; Nedrebø, BG; Nygård, O; Refsum, H; Ueland, PM | 1 |
| Peterson, JC; Spence, JD | 1 |
| Tonstad, S | 1 |
| Boddie, AM; Coates, RJ; Dembure, PP; Elsas, LJ; Pasquali, M; Steen, MT; Sullivan, KM | 1 |
| Nygård, O; Refsum, H; Ueland, PM; Vollset, SE | 2 |
| Artuch, R; Lambruschini, N; Moyano, D; Valls, C; Vilaseca, MA | 1 |
| Baig, SM; Bednar, I; Halawa, A; Parvez, SH; Qureshi, GA | 1 |
| Blom, HJ; Eskes, TK; Gabreëls, F; Smeitink, JA; Stevens, EM; Trijbels, FJ; van den Heuvel, LP; van der Put, NM | 1 |
| Clarke, R; Frost, C; Khaw, KT; Refsum, H; Sherliker, P; Ueland, PM; Ulvik, A; Woodhouse, P | 1 |
| Aull, S; Korninger, L; Lalouschek, W; Mannhalter, C; Pabinger-Fasching, I; Schmid, RW; Schnider, P; Zeiler, K | 1 |
| Bergman, SM; Morgan, SL; Tamura, T | 2 |
| Adão, M; Azinheira, J; Bordalo-Sá, AL; Correia, JM; Luís, AS; Pina, JE; Reis, HP; Reis, RP; Santos, L; Tavares, J | 2 |
| Bresson-Vautrin, C; Chalopin, JM; Ducloux, D; Fournier, V; Gibey, R; Rebibou, JM | 1 |
| Evans, A; Gey, KF; Harmon, DL; McCrum, EE; McMaster, D; Patterson, CC; Whitehead, AS; Woodside, JV; Yarnell, JW; Young, IS | 1 |
| Goulding, C; Matthews, RG; Sheppard, C | 1 |
| Fowler, B | 1 |
| Gérard, M; Ogier de Baulny, H; Saudubray, JM; Zittoun, J | 1 |
| Brönstrup, A; Pietrzik, K | 2 |
| Abrahamsson, L; Friman, C; Nilsson, B; Norberg, B; Pettersson, T | 1 |
| Arn, PH; Driscoll, DJ; Rosenblatt, DS; Williams, CA; Zori, RT | 1 |
| Auinger, M; Buxbaum, M; Enzenberger, B; Födinger, M; Hörl, WH; Mannhalter, C; Prischl, F; Sunder-Plassmann, G; Vychytil, A; Wiesholzer, M; Wölfl, G | 1 |
| Wilcken, DE | 1 |
| Tsuchiya, S | 1 |
| Sato, K | 1 |
| Cattell, H; Davies, G; Hudson, P; McCaddon, A; Tandy, S | 1 |
| Gretz, DM; Henning, SM; Jacob, RA; James, SJ; Miller, BJ; Pogribny, IP; Swendseid, ME; Taylor, PC | 1 |
| Chamorro, A; Deulofeu, R; Piera, C; Vila, N | 1 |
| Boddie, AM; Dembure, PP; Elsas, LJ; Fisher, AJ; Macmahon, W; Saxe, D; Steen, MT; Sullivan, KM | 1 |
| Aitken, C; Fenech, M; Rinaldi, J | 1 |
| Devitt, H; Dowell, AC; Lucock, M; Schorah, CJ | 1 |
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| Buchmayer, H; Födinger, M; Heinz, G; Hörl, WH; Kletzmayr, J; Papagiannopoulos, M; Rasoul-Rockenschaub, S; Sunder-Plassmann, G | 1 |
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| Födinger, M; Sunder-Plassmann, G; Winkelmayer, WC | 1 |
| Bie, RB; Bolann, BJ; Grøttum, KA; Loraas, A; Refsum, H; Schjøth, A; Schneede, J; Solli, JD; Stallemo, A; Stokkeland, M; Ueland, PM | 1 |
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| BUCHANAN, JM; ELFORD, HL; LOUGHLIN, RE | 1 |
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| Bleich, S; Kornhuber, J; Kurth, C; Lewczuk, P; Reulbach, U; Steinhoff, BJ; Wegerer, V | 1 |
| Eberle, C; Födinger, M; Skoupy, S; Sunder-Plassmann, G; Winkelmayer, WC | 1 |
| Daftary, AR; Ness, RB; Patrick, TE; Powers, RW; Roberts, JM | 1 |
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| Eberle, C; Feix, A; Födinger, M; Sunder-Plassmann, G; Winkelmayer, WC | 1 |
| Braun, S; Kastrati, A; Koch, W; Kölling, K; Mehilli, J; Ndrepepa, G; Schömig, A | 2 |
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| Armbruster, FP; Dschietzig, T; Dura, A; Nelle, E; Reich, M; Schwarz, J; Watanabe, F; Wintgens, KF | 1 |
| Brouwer-Brolsma, EM; de Groot, LC; Dhonukshe-Rutten, RA; Enneman, AW; Ham, AC; Lips, P; Swart, KM; Uitterlinden, AG; van der Cammen, TJ; van der Velde, N; van der Zwaluw, NL; van Dijk, SC; van Meurs, J; van Schoor, NM; van Wijngaarden, JP; Zillikens, MC | 1 |
| Allen, LH; Brito, A; Fedosov, SN; Green, R; Miller, JW | 1 |
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| Benser, J; Breidenassel, C; Castillo, MJ; Ferrari, M; Gómez-Martínez, S; González-Gross, M; Kafatos, A; Manios, Y; Mielgo-Ayuso, J; Molnar, D; Moreno, LA; Palacios, G; Ruiz, JR; Sjöström, M; Stehle, P; Valtueña, J; Vicente-Rodriguez, G; Widhalm, K | 1 |
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| Arthurs, AL; Jankovic-Karasoulos, T; Roberts, CT; Smith, MD; Williamson, JM | 1 |
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| Dastidar, R; Sikder, K | 1 |
| de Lourdes Samaniego-Vaesken, M; Marco Mendez, R; Montero-Bravo, AM; Morais-Moreno, C; Partearroyo, T; Puga, AM; Ruperto, M; Varela-Moreiras, G; Vicente-Arche, Á | 1 |
| Florindo, C; Gaspar, A; Janeiro, P; Lipari Pinto, P; Mexia, S; Rocha, H; Santos, RL; Tavares de Almeida, I; Vilarinho, L | 1 |
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| Amorim, PMS; Andreoni, S; Bonilha, AC; D Almeida, V; Demarzo, M; Guerra-Shinohara, EM; Liu, ASLW; Mapurunga, M; Moscardi, AVS; Neves, FJ; Pinto, J; Ramos, LR; Tomita, LY | 1 |
| Fu, L; Hu, YQ; Wang, Y | 1 |
| Abdulhalim, EN; El-Bassyouni, HT; Hamed, K; Hashem, SA; Kamel, SM; Khedr, AA; Youness, ER | 1 |
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| Chen, S; Fang, AP; He, TT; Huang, BX; Huang, RZ; Huang, ZH; Li, SY; Liu, XZ; Liu, ZY; Lu, XT; Luo, Y; Maierhaba, W; Mo, QW; Wang, YF; Wang, YN; Yang, MT; Zhang, XG; Zhu, HL | 1 |
| Alatas, İO; Atalay, E; Demir, SS; Ozalp, O; Sozer, O; Yildirim, N | 1 |
| Bennett, D; Campbell, H; Duthie, S; Eguiagaray, IM; Li, X; Little, J; MacFarlane, AJ; McNulty, H; Momoli, F; Montazeri, A; Munger, R; Rubini, M; Senekal, M; Theodoratou, E; Wang, L | 1 |
| Chen, WJ; Hsueh, YM; Huang, CY; Huang, YL; Lee, HL; Lin, YC; Pu, YS; Shiue, HS | 1 |
| Bhandari, N; Chowdhury, R; Kvestad, I; Manapurath, R; Strand, TA; Taneja, S; Yajnik, CS | 1 |
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| Costigliolo, F; Esposito, P; Garibotto, G; Picciotto, D; Saio, M; Sofia, A; Valli, A; Verzola, D; Viazzi, F | 1 |
| Mallhi, AK; Twum, F; Zhang, J | 1 |
| Ben-Shlomo, I; Feferkorn, I; Gluska, H; Manzur, NF; Skvirsky, S; Wiener-Megnazi, Z | 1 |
| Chen, L; Hong, H; Leng, H; Li, W; Song, C; Yang, Z; Zhong, Y | 1 |
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| Chandratheva, A; Chen, J; Coughlan, CH; Goodison, W; Murphy, E; Rees, A | 1 |
| Chen, G; Chen, X; Feng, Y; Liu, Y; Luo, J; Yang, Y | 1 |
| Chen, Y; Du, M; Li, B; Lin, Y; Su, C; Wang, X; Wei, H; Wu, S; Yuan, S; Zhu, C | 1 |
| Noori, SH; Shawkat Ahmed, H | 1 |
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| Chen, M; Huang, W; Kang, Z; Li, Q; Liu, T; Shu, Y; Zhang, W; Zhou, H | 1 |
| Choi, R; Chun, G; Lee, EH; Lee, SG; Park, W | 1 |
| Bhidayasiri, R; Garcia-Ruiz, P; Müller, T; Odin, P; Phokaewvarangkul, O; Riederer, P | 1 |
| Cheng, X; Long, L; Peng, H; Shen, L; Wang, X; Xia, C; Yang, C; Yang, Y; Zhou, Y | 1 |
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| Feng, W; Gao, H; Lu, Y; Pan, D; Smith, JD; Song, G; Su, M; Sun, G; Sun, J; Wang, S; Wang, X; Wang, Y; Xu, D; Yan, Q | 1 |
| Al-Kassab-Córdova, A; Alarcon-Braga, EA; Benites-Zapata, VA; Cabrera-Guzmán, JC; Hernandez-Bustamante, EA; Herrera-Añazco, P; Ulloque-Badaracco, JR | 1 |
| Al-Khlaiwi, T; Almushawah, A; Alsomali, A; Habib, SA; Habib, SS | 1 |
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| Chung, HW; Hsu, YH; Tu, MC; Wu, WC; Yang, JJ | 1 |
| Horiguchi, S; Kawabata, T; Kubo, Y; Shoji, K; Tajima, A | 1 |
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290 review(s) available for homocysteine and vitamin b 12
| Article | Year |
|---|---|
[Homocystinuria. Clinical review and report of a case].
Topics: Amino Acids, Sulfur; Bone Diseases; Cystathionine beta-Synthase; Eye Diseases; Homocysteine; Homocystine; Homocystinuria; Humans; Intestinal Absorption; Methyltransferases; Nervous System Diseases; Skin Diseases; Tetrahydrofolate Dehydrogenase; Thrombosis; Vitamin B 12 | 1976 |
Multiple sclerosis and vitamin B12 metabolism.
Topics: Animals; Erythrocytes; Homocysteine; Humans; Multiple Sclerosis; Vitamin B 12; Vitamin B 12 Deficiency | 1992 |
The effects of vitamins B12, B6, and folate on blood homocysteine levels.
Topics: Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Pyridoxine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 1992 |
Homocysteine, folic acid, and the prevention of vascular disease.
Topics: Arterial Occlusive Diseases; Arteriosclerosis; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Metabolism, Inborn Errors; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 1989 |
[Sulfate reduction and biosynthesis of sulfur containing amino acids (author's transl)].
Topics: Amino Acids, Sulfur; Bacteria; Cysteine; Feedback; Homocysteine; Hydrogen Sulfide; Methionine; Oxidation-Reduction; Sulfates; Sulfur; Sulfur Acids; Sulfuric Acids; Thiosulfates; Vitamin B 12 | 1974 |
Corrinoid-dependent enzymic reactions.
Topics: Acetates; Alcohol Oxidoreductases; Amino Acid Isomerases; Amino Alcohols; Carbon Dioxide; Cobamides; Coenzymes; Ethanolamines; Glutamates; Glycerol; Glycols; Homocysteine; Isomerases; Lyases; Malonates; Methane; Methyltransferases; Ribonucleotides; Vitamin B 12 | 1972 |
Observations on the biochemical basis of megaloblastic anaemia.
Topics: Anemia, Macrocytic; Deoxyuridine; DNA; Erythrocytes, Abnormal; FIGLU Test; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Nervous System Diseases; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymine Nucleotides; Vitamin B 12; Vitamin B 12 Deficiency | 1972 |
The biosynthesis of methionine.
Topics: Animals; Apoproteins; Bacteria; Catalysis; Chemical Phenomena; Chemistry; Cobamides; Drug Stability; Enzyme Activation; Escherichia coli; Flavins; Homocysteine; Methionine; Methyltransferases; Molecular Weight; Oxidation-Reduction; Plants; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1973 |
Vitamin-responsive inherited diseases affecting the nervous system.
Topics: Coenzymes; Genotype; Homocysteine; Humans; Metabolism, Inborn Errors; Methionine; Molecular Biology; Mutation; Neurologic Manifestations; Phenotype; Pyridoxine; Vitamin B 12; Vitamins | 1974 |
Enzymatic reactions involving corrinoids.
Topics: Acetates; Caproates; Enzymes; Homocysteine; Isomerases; Lysine; Methane; Oxidoreductases; Vitamin B 12 | 1968 |
Defective vitamin B 12 metabolism in the human being: changes in methionine and methylmalonic acid excretion.
Topics: Amino Acids; Animals; Brain; Coenzymes; Homocysteine; Homocystine; Humans; Infant; Male; Malonates; Metabolic Diseases; Methionine; Rats; Vitamin B 12 | 1969 |
Inherited defects of B12 metabolism.
Topics: Amino Acids; Animals; Coenzymes; Homocysteine; Humans; Malonates; Metabolism, Inborn Errors; Propionates; Vitamin B 12; Vitamin B 12 Deficiency | 1970 |
Drugs, toxins and dietary amino acids affecting vitamin B12 or folic acid absorption or utilization.
Topics: Amino Acids; Anemia, Macrocytic; Contraceptives, Oral; Diet; DNA; Ethanol; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Glycine; Homocysteine; Humans; Malabsorption Syndromes; Methionine; Pharmacology; Serine; Toxins, Biological; Vitamin B 12 | 1970 |
Roles of vitamin B 12 and folic acid in methionine synthesis.
Topics: Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Transferases; Vitamin B 12 | 1970 |
The deoxyuridine suppression test: a review of its clinical and research applications.
Topics: Alcoholism; Anemia, Hemolytic; Anticonvulsants; Bone Marrow Cells; Bone Marrow Diseases; Cells; Deoxyuridine; Erythrocytes, Abnormal; Female; Fluorouracil; Folic Acid; Folic Acid Deficiency; Formyltetrahydrofolates; Homocysteine; Humans; Hypothyroidism; Lymphocyte Activation; Methionine; Pregnancy; Pregnancy Complications; Statistics as Topic; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 1981 |
A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes.
Topics: Arteriosclerosis; Coronary Disease; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Pyridoxine; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 1995 |
How to diagnose cobalamin deficiency.
Topics: Gastrins; History, 19th Century; History, 20th Century; Homocysteine; Humans; Methylmalonic Acid; Pepsinogens; Schilling Test; Vitamin B 12; Vitamin B 12 Deficiency | 1994 |
Vitamin nutrition status and homocysteine: an atherogenic risk factor.
Topics: Arteriosclerosis; Case-Control Studies; Coronary Disease; Folic Acid; Homocysteine; Humans; Nutritional Status; Pyridoxine; Risk Factors; Vitamin B 12 | 1994 |
Homocysteinemia: association of a metabolic disorder with vascular disease and thrombosis.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Blood Coagulation Factors; Blood Platelets; Child; Cystathionine beta-Synthase; Endothelium, Vascular; Fibrinolytic Agents; Folic Acid Deficiency; Homocysteine; Humans; Incidence; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Penicillamine; Risk Factors; Thrombosis; Vascular Diseases; Vitamin B 12; Vitamin B 6 Deficiency; Vitamins | 1993 |
Update of new risk factors and prevention of neural-tube defects.
Topics: Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Neural Tube Defects; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 1993 |
More folic acid for everyone, now.
Topics: Adult; Aged; Anencephaly; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Infant, Newborn; Male; Pregnancy; Risk Factors; Spinal Dysraphism; United States; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Homocysteine and neural tube defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Infant, Newborn; Mice; Neural Tube Defects; Pregnancy; Randomized Controlled Trials as Topic; Rats; Vitamin B 12 | 1996 |
Homocysteine and coronary atherosclerosis.
Topics: Coronary Artery Disease; Folic Acid; Homocysteine; Homocystinuria; Humans; Pyridoxine; Risk Factors; Vitamin B 12 | 1996 |
High prevalence of cobalamin deficiency in the elderly.
Topics: Aged; Hematologic Diseases; Homocysteine; Humans; Mental Disorders; Methylmalonic Acid; Nervous System Diseases; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Homocysteinemia and vascular disease in end-stage renal disease.
Topics: Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Male; Methionine; Middle Aged; Pyridoxine; Thrombosis; Vitamin B 12 | 1996 |
Folate nutrition and older adults: challenges and opportunities.
Topics: Aged; Aged, 80 and over; Aging; Female; Folic Acid; Food, Fortified; Homocysteine; Homocystinuria; Humans; Male; Nutritional Status; Risk Factors; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Vitamin B12 replacement. To B12 or not to B12?
Topics: Family Practice; Homocysteine; Humans; Methylmalonic Acid; Prevalence; Research Design; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Folate, vitamin B12, and neuropsychiatric disorders.
Topics: Depressive Disorder; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylation; Multiple Sclerosis; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Vitamin B-12 deficiency in the elderly: current dilemmas.
Topics: Acyl Coenzyme A; Aged; Aged, 80 and over; Female; Homocysteine; Humans; Male; Methionine; Methylmalonic Acid; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Homocysteine and cardiovascular disease.
Topics: Arteriosclerosis; Cardiovascular Diseases; Coronary Artery Disease; Female; Folic Acid; Folic Acid Deficiency; Forecasting; Homocysteine; Humans; Intracranial Arteriosclerosis; Male; Peripheral Vascular Diseases; Prevalence; Risk Factors; Safety; Thromboembolism; Vitamin B 12; Vitamin B 12 Deficiency | 1998 |
Hyperhomocysteinemia as a cause of vascular occlusion in end-stage-renal disease.
Topics: Cardiovascular Diseases; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Hematinics; Homocysteine; Humans; Kidney Failure, Chronic; Kidney Transplantation; Pyridoxine; Renal Dialysis; Vitamin B 12 | 1998 |
Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomised trials. Homocysteine Lowering Trialists' Collaboration.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Folic Acid; Food, Formulated; Hematinics; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Pyridoxine; Randomized Controlled Trials as Topic; Vitamin B 12 | 1998 |
Methylenetetrahydrofolate reductase and methionine synthase: biochemistry and molecular biology.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Animals; Enzyme Activation; Escherichia coli; Homocysteine; Homocystinuria; Homozygote; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Molecular Sequence Data; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Vitamin B 12 | 1998 |
Genetic defects of folate and cobalamin metabolism.
Topics: Absorption; Amino Acid Metabolism, Inborn Errors; Animals; Coenzymes; Fibroblasts; Folic Acid; Homocysteine; Humans; Lysosomes; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Tetrahydrofolates; Transcobalamins; Vitamin B 12 | 1998 |
Remethylation defects: guidelines for clinical diagnosis and treatment.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Betaine; Child, Preschool; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Practice Guidelines as Topic; Vitamin B 12 | 1998 |
Relevance of vitamins, homocysteine and other metabolites in neuropsychiatric disorders.
Topics: Central Nervous System Diseases; Citrates; Demyelinating Diseases; Folic Acid; Homocysteine; Humans; Mental Disorders; Methionine; Methylmalonic Acid; Vitamin B 12 | 1998 |
Vitamins B12, B6 and folate as determinants of homocysteine concentration in the healthy population.
Topics: Folic Acid; Food, Fortified; Homocysteine; Humans; Nutritional Status; Pyridoxine; Vitamin B 12 | 1998 |
[Transcobalamin II deficiency].
Topics: Anemia, Megaloblastic; Biomarkers; Diagnosis, Differential; Homocysteine; Humans; Infant; Mutation; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 1998 |
[Inherited disorders of cobalamin metabolism].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Biomarkers; Child, Preschool; Diagnosis, Differential; Homocysteine; Humans; Infant; Infant, Newborn; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Mutation; Prognosis; Vitamin B 12; Vitamin B 12 Deficiency | 1998 |
The role of homocysteine, folate and other B-vitamins in the development of atherosclerosis.
Topics: Arteriosclerosis; Coronary Disease; Folic Acid; Hematinics; Homocysteine; Humans; Middle Aged; Pyridoxine; Risk Factors; Vitamin B 12; Vitamin B Complex | 1997 |
Enzyme-catalyzed methyl transfers to thiols: the role of zinc.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Archaea; Catalysis; Dimethylallyltranstransferase; Homocysteine; Methylation; Sulfhydryl Compounds; Vitamin B 12; Zinc | 1997 |
Homocysteine, vitamins, and cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Homocysteine; Humans; Pyridoxine; Vitamin B 12 | 1998 |
Can dietary supplements with folic acid or vitamin B6 reduce cardiovascular risk? Design of clinical trials to test the homocysteine hypothesis of vascular disease.
Topics: Cardiovascular Diseases; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pyridoxine; Randomized Controlled Trials as Topic; Research Design; Vitamin B 12 | 1998 |
B vitamins and homocysteine in cardiovascular disease and aging.
Topics: Aging; Cardiovascular Diseases; Diet; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Pyridoxine; Risk Factors; Vitamin B 12; Vitamin B Deficiency | 1998 |
Hyperhomocysteinemia, atherosclerosis and thrombosis.
Topics: Adult; Aged; Animals; Arteriosclerosis; Avitaminosis; Case-Control Studies; Clinical Trials as Topic; Cohort Studies; Cross-Sectional Studies; Cystathionine beta-Synthase; Female; Folic Acid; Gene Frequency; Homocysteine; Homocystinuria; Hormone Replacement Therapy; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle, Smooth, Vascular; Oxidoreductases Acting on CH-NH Group Donors; Prevalence; Primates; Prospective Studies; Pyridoxine; Risk Factors; Smoking; Tamoxifen; Thrombophilia; Thrombosis; Vitamin B 12 | 1999 |
[Hyperhomocysteinemia as a risk factor for venous thrombosis].
Topics: Adult; Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Pyridoxine; Randomized Controlled Trials as Topic; Venous Thrombosis; Vitamin B 12 | 1999 |
Laboratory diagnosis of vitamin B12 and folate deficiency: a guide for the primary care physician.
Topics: Antibodies; Clinical Laboratory Techniques; Clinical Trials as Topic; Decision Trees; Diagnosis, Differential; Erythrocytes; Folic Acid Deficiency; Hematologic Diseases; Homocysteine; Humans; Intrinsic Factor; Methylmalonic Acid; Nervous System Diseases; Parietal Cells, Gastric; Primary Health Care; Schilling Test; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
[Diagnosis of vitamin B12 deficiency: only apparently child's play].
Topics: Aging; Anemia, Pernicious; Blood Cell Count; Diagnosis, Differential; Folic Acid Deficiency; Gastritis, Atrophic; Gastroscopy; Homocysteine; Humans; Methylmalonic Acid; Schilling Test; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
[Hyperhomocysteinemia: a risk factor for arterial and venous thrombosis].
Topics: Arteriosclerosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pyridoxine; Risk Factors; Thromboembolism; Vitamin B 12 | 1999 |
What is homocysteine?
Topics: Dietary Supplements; Folic Acid; Heart Diseases; Homocysteine; Humans; Pyridoxine; Risk Factors; Vitamin B 12 | 1999 |
Plasma homocysteine as a cardiovascular risk factor: causal, consequential, or of no consequence?
Topics: Aged; Cardiovascular Diseases; Case-Control Studies; Cross-Sectional Studies; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Incidence; Male; Meta-Analysis as Topic; Prospective Studies; Pyridoxine; Retrospective Studies; Risk; Risk Factors; Smoking; Vitamin B 12 | 1999 |
Hyperhomocysteinemia in organ transplantation.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Organ Transplantation; Polymorphism, Genetic; Pyridoxine; Risk Factors; Vitamin B 12 | 2000 |
Homocysteine, folate enzymes and neural tube defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Nutritional Requirements; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Pregnancy Complications; Vitamin B 12 | 1999 |
Preventive health care, 2000 update: screening and management of hyperhomocysteinemia for the prevention of coronary artery disease events. The Canadian Task Force on Preventive Health Care.
Topics: Aged; Arteriosclerosis; Canada; Coronary Disease; Dietary Supplements; Disease Susceptibility; Fasting; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mass Screening; Methionine; Preventive Medicine; Pyridoxine; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12 | 2000 |
Cobalamin and folate evaluation: measurement of methylmalonic acid and homocysteine vs vitamin B(12) and folate.
Topics: Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Homocysteine and renal disease.
Topics: Adult; Arteriosclerosis; Cardiovascular Diseases; Case-Control Studies; Child; Endothelium, Vascular; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Kidney Failure, Chronic; Kidney Transplantation; Life Tables; Male; Methionine; Peritoneal Dialysis; Prospective Studies; Pyridoxine; Renal Dialysis; Survival Analysis; Thrombophilia; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2000 |
Vascular complications of severe hyperhomocysteinemia in patients with homocystinuria due to cystathionine beta-synthase deficiency: effects of homocysteine-lowering therapy.
Topics: Adolescent; Adult; Aged; Australia; Child; Child, Preschool; Cohort Studies; Cystine; Drug Resistance; Female; Folic Acid; Follow-Up Studies; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Infant; Ireland; Male; Methionine; Middle Aged; Netherlands; Pyridoxine; Risk; Risk Factors; Thrombophilia; Vascular Diseases; Vitamin B 12 | 2000 |
Vitamin supplements and cardiovascular risk: review of the randomized trials of homocysteine-lowering vitamin supplements.
Topics: Adult; Aged; Cardiovascular Diseases; Clinical Trials as Topic; Diet; Double-Blind Method; Drug Synergism; Europe; Female; Folic Acid; Forecasting; Genetic Variation; Homocysteine; Humans; Hyperhomocysteinemia; Male; Meta-Analysis as Topic; Middle Aged; Multicenter Studies as Topic; North America; Prospective Studies; Randomized Controlled Trials as Topic; Research Design; Risk Factors; Treatment Outcome; Vitamin B 12 | 2000 |
Homocysteine and neurologic disease.
Topics: Brain Diseases; Epilepsy; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Pyridoxine; Vascular Diseases; Vitamin B 12 | 2000 |
Therapeutic potential of total homocysteine-lowering drugs on cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Clinical Trials as Topic; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Transplantation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Renal Dialysis; Risk Factors; Vitamin B 12 | 2000 |
[Nutrition, dietary supplementation and coronary heart disease].
Topics: Coronary Disease; Dietary Fats; Dietary Supplements; Feeding Behavior; Female; Fish Oils; Folic Acid; Homocysteine; Humans; Lipoproteins; Male; Nutritional Physiological Phenomena; Nuts; Phytosterols; Pyridoxine; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12 | 2000 |
Folic acid, vitamins B6 and B12: relation to homocysteine and cardiovascular disease.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Pyridoxine; Risk Factors; Vitamin B 12 | 2001 |
Rationale for risk reduction of cardiovascular disease using homocysteine concentration in blood and plasma as biomarker: support by clinical data.
Topics: Biomarkers; Cardiovascular Diseases; Dietary Supplements; Folic Acid; Homocysteine; Humans; Nutrition Policy; Pyridoxine; Risk Factors; Vitamin B 12 | 2001 |
Homocysteine, vitamins, and coronary artery disease. Comprehensive review of the literature.
Topics: Clinical Trials as Topic; Coronary Disease; Diet; Folic Acid; Homocysteine; Humans; Pyridoxine; Risk Factors; Vitamin B 12 | 2000 |
[Homocysteine and cardiovascular risk].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Arteriosclerosis; Clinical Trials as Topic; Coronary Artery Disease; Disease Models, Animal; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological; Vitamin B 12 | 2001 |
[Homocysteine--a risk factor for atherosclerosis].
Topics: Antioxidants; Arteriosclerosis; Disease Progression; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Oxidative Stress; Risk Factors; Thrombosis; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2001 |
Folate, vitamin B12 and homocysteine in relation to birth defects and pregnancy outcome.
Topics: Congenital Abnormalities; Deficiency Diseases; Developing Countries; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Homocysteine, vascular dementia and Alzheimer's disease.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Dementia, Vascular; Double-Blind Method; Folic Acid; Homocysteine; Humans; Middle Aged; Placebos; Risk Factors; Time Factors; Vitamin B 12; Vitamin B 6 | 2001 |
Nutritional regulation of homocysteine: effects of drugs.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Drug Interactions; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Methionine; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; S-Adenosylmethionine; Vitamin B 12; Vitamin B 6 | 2001 |
Cardiovascular risk in the Asia-Pacific region from a nutrition and metabolic point of view: vitamin deficiencies.
Topics: Aged; Antioxidants; Asia; Avitaminosis; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pacific Islands; Risk Factors; Vitamin B 12; Vitamin B 6 | 2001 |
Therapy of hyperhomocysteinemia in end-stage renal disease patients.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Renal Replacement Therapy; Vitamin B 12; Vitamin B 6 | 2001 |
Assessment of homocysteine as a cardiovascular risk factor in clinical practice.
Topics: Biomarkers; Blood Chemical Analysis; Cardiovascular Diseases; Clinical Trials as Topic; Diet; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Mutation; Risk Factors; Vitamin B 12 | 2001 |
Emergent cardiovascular risk factor: homocysteine.
Topics: Blood Chemical Analysis; Cardiovascular Diseases; Folic Acid; Health Education; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Vitamin B 12; Vitamin B 6 | 2002 |
Plasma homocysteine: a new risk factor for Alzheimer's disease?
Topics: Alzheimer Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2002 |
Editorial: Renal failure, homocysteine and the pharmacology of vitamin B12.
Topics: Homocysteine; Humans; Kidney Failure, Chronic; Vitamin B 12 | 2002 |
Homocysteine, B vitamins, and cognitive deficit in the elderly.
Topics: Aging; Cognition Disorders; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 2002 |
Homocysteine and occlusive arterial disease.
Topics: Arteriosclerosis; Diet; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Risk Factors; Vitamin B 12 | 2002 |
Homocyst(e)ine and coronary heart disease: pharmacoeconomic support for interventions to lower hyperhomocyst(e)inaemia.
Topics: Coronary Disease; Dietary Supplements; Economics, Pharmaceutical; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Vitamin B 12; Vitamin B 6 | 2002 |
Methods for measuring sulfur amino acid metabolism.
Topics: Amino Acids, Sulfur; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kinetics; Methionine; Methylation; Models, Biological; Radioisotope Dilution Technique; Vitamin B 12 | 2002 |
Vegetarian lifestyle and monitoring of vitamin B-12 status.
Topics: Analysis of Variance; Diet, Vegetarian; Hemoglobins; Homocysteine; Humans; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Pharmacotherapy of hyperhomocysteinaemia in patients with thrombophilia.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Pyridoxine; Renal Insufficiency; Thrombophilia; Vitamin B 12; Vitamins | 2002 |
Pemetrexed safety and dosing strategy.
Topics: Antimetabolites, Antineoplastic; Clinical Trials as Topic; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Homocysteine; Humans; Methylmalonic Acid; Neoplasms; Pemetrexed; Thymidylate Synthase; Vitamin B 12 | 2002 |
The methionine-homocysteine cycle and its effects on cognitive diseases.
Topics: Alzheimer Disease; Cardiovascular Diseases; Cognition Disorders; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Memory Disorders; Methionine; Methionine Adenosyltransferase; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2003 |
Homocysteine and Alzheimer's disease.
Topics: Age Factors; Aged; Alzheimer Disease; Apolipoproteins E; Brain; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Nutrition Policy; Risk Factors; Sex Factors; United States; Vitamin B 12; Vitamin B 6 | 2003 |
Homocysteine in the context of cobalamin metabolism and deficiency states.
Topics: Female; Homocysteine; Humans; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Reducing coronary artery disease by decreasing homocysteine levels.
Topics: Coronary Disease; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Nurse's Role; Patient Education as Topic; Primary Prevention; Risk Factors; Vitamin B 12; Vitamin B 6 | 2003 |
Vitamins, homocysteine and cardiovascular risk.
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Folic Acid; Homocysteine; Humans; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamins | 2002 |
[Diagnosis of vitamin B12 deficiency--time for reflection].
Topics: Biomarkers; Homocysteine; Humans; Methylmalonic Acid; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
[Vitamin B12 in the Nordic countries. Deficiency, diagnosis, treatment in Sweden].
Topics: Biomarkers; Homocysteine; Humans; Methylmalonic Acid; Practice Patterns, Physicians'; Scandinavian and Nordic Countries; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Total plasma homocysteine and restenosis after percutaneous coronary angioplasty: current evidence.
Topics: Angioplasty, Balloon, Coronary; Biomarkers; Coronary Restenosis; Folic Acid; Homocysteine; Humans; Risk Assessment; Risk Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2003 |
[BIOSYNTHESIS OF METHYL GROUP OF METHIONINE].
Topics: Alkylation; Amino Acids; Cysteine; Folic Acid; Homocysteine; Metabolism; Methionine; Research; Vitamin B 12 | 1964 |
Helicobacter pylori infection, vitamin B12 and homocysteine. A review.
Topics: Anemia, Pernicious; Gastritis, Atrophic; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Intestinal Absorption; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
[Optimal use of markers for cobalamin/folate status. Results from a survey in a group of psychogeriatric patients].
Topics: Aged; Biomarkers; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Mental Disorders; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Homocysteine and essential hypertension.
Topics: Antioxidants; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Muscle, Smooth, Vascular; Nitric Oxide; Vitamin B 12 | 2003 |
[Homocysteine as a coronary risk factor].
Topics: Alcoholic Beverages; Arteriosclerosis; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Disease; Diet; Female; Folic Acid; Glycine max; Homocysteine; Humans; Hyperhomocysteinemia; Male; Platelet Aggregation; Risk Factors; Vitamin B 12; Vitamin B 6 | 2003 |
Update on cobalamin, folate, and homocysteine.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Metabolism, Inborn Errors; Polymorphism, Genetic; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Meta-analysis of plasma homocysteine, serum folate, serum vitamin B(12), and thermolabile MTHFR genotype as risk factors for retinal vascular occlusive disease.
Topics: Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Retinal Artery Occlusion; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2003 |
DACH-LIGA homocystein (german, austrian and swiss homocysteine society): consensus paper on the rational clinical use of homocysteine, folic acid and B-vitamins in cardiovascular and thrombotic diseases: guidelines and recommendations.
Topics: Austria; Cardiovascular Diseases; Female; Folic Acid; Germany; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Switzerland; Thrombosis; Vitamin B 12; Vitamin B 6 | 2003 |
Genetic determinants of folate and vitamin B12 metabolism: a common pathway in neural tube defect and Down syndrome?
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Down Syndrome; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Polymorphism, Genetic; Transcobalamins; Vitamin B 12 | 2003 |
Patients with atherosclerotic vascular disease: how low should plasma homocyst(e)ine levels go?
Topics: Arteriosclerosis; Clinical Trials as Topic; Dipeptides; Folic Acid; Homocysteine; Homocystine; Humans; Pyridoxine; Risk Factors; Vitamin B 12 | 2001 |
Methylenetetrahydrofolate reductase and transcobalamin genetic polymorphisms in human spontaneous abortion: biological and clinical implications.
Topics: Abortion, Spontaneous; Animals; Embryonic Development; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Transcobalamins; Vitamin B 12 | 2004 |
[Homocysteine and neuropsychiatric disorders].
Topics: Alzheimer Disease; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mental Disorders; Parkinson Disease; Risk Factors; Stroke; Vitamin B 12; Vitamin B 6 | 2004 |
Evidence for a protective (synergistic?) effect of B-vitamins and omega-3 fatty acids on cardiovascular diseases.
Topics: Cardiovascular Diseases; Dietary Supplements; Drug Synergism; Fatty Acids, Omega-3; Folic Acid; Homocysteine; Humans; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12; Vitamin B 6 | 2004 |
Role of magnesium, coenzyme Q10, riboflavin, and vitamin B12 in migraine prophylaxis.
Topics: Adult; Antioxidants; Coenzymes; Female; Homocysteine; Humans; Magnesium; Male; Migraine Disorders; Riboflavin; Ubiquinone; Vitamin B 12 | 2004 |
A critical evaluation of the relationship between serum vitamin B, folate and total homocysteine with cognitive impairment in the elderly.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Cognition Disorders; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12 | 2004 |
[Nitrous oxide. Sense or nonsense for today's anaesthesia].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Analgesia; Anesthesiology; Anesthetics, Inhalation; Dose-Response Relationship, Drug; History, 18th Century; History, 19th Century; History, 20th Century; Homocysteine; Humans; Nitrous Oxide; Surgical Procedures, Operative; Vitamin B 12 | 2004 |
Vitamin B12 and folate depletion in cognition: a review.
Topics: Cognition; Cognition Disorders; Dementia; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
[Hyperhomocysteinemia: from theory and practice in the treatment of thrombophilias].
Topics: Administration, Oral; Anticoagulants; Blood Coagulation Tests; Cardiovascular Diseases; Double-Blind Method; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Marfan Syndrome; Multicenter Studies as Topic; Mutation; Polymorphism, Genetic; Randomized Controlled Trials as Topic; Risk Factors; Thrombophilia; Time Factors; Venous Thrombosis; Vitamin B 12; Vitamin B 6 | 2004 |
Menopause, the cardiovascular risk factor homocysteine, and the effects of treatment.
Topics: Cardiovascular Diseases; Estrogen Replacement Therapy; Female; Folic Acid; Homocysteine; Humans; Menopause; Risk Factors; Vitamin B 12; Vitamin B 6 | 2004 |
Homocysteine and cardiovascular disease: interactions between nutrition, genetics and lifestyle.
Topics: Avitaminosis; Cardiovascular Diseases; Creatinine; Folic Acid; Homocysteine; Humans; Incidence; Kidney Diseases; Life Style; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Physiological Phenomena; Polymorphism, Genetic; Pyridoxal; Riboflavin; Vitamin B 12 | 2004 |
Treatment of depression: time to consider folic acid and vitamin B12.
Topics: Brain; Depressive Disorder, Major; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Mapping the theories of preeclampsia: the role of homocysteine.
Topics: Adult; Age Factors; Biomarkers; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Maternal Age; Parity; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Primary Prevention; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Survival Rate; Vitamin B 12 | 2005 |
What is new in vitamin B(12)?
Topics: Animals; Homocysteine; Humans; Hyperhomocysteinemia; Intestinal Absorption; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
[Cobalamin--a critical nutritive element in old age].
Topics: Aged; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
[Group B vitamins as new variables related to the cardiovascular risk].
Topics: Adult; Aged; Arteriosclerosis; Cardiovascular Diseases; Case-Control Studies; Clinical Trials as Topic; Cross-Over Studies; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Primary Prevention; Prospective Studies; Retrospective Studies; Risk; Risk Factors; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2005 |
[Determination and utilisation of the plasmatic concentration of homocysteine in clinical practice].
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12 | 2005 |
Water-soluble vitamins: research update.
Topics: Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Neural Tube Defects; Niacinamide; Nutritional Requirements; Pregnancy; Riboflavin; Riboflavin Deficiency; Solubility; Thiamine; Thiamine Deficiency; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Complex; Vitamin B Deficiency | 2005 |
Novel and established markers of cobalamin deficiency: complementary or exclusive diagnostic strategies.
Topics: Biomarkers; Diagnosis, Differential; Homocysteine; Humans; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Homocysteine, folic acid and vitamin B12 in relation to pre- and postnatal health aspects.
Topics: Congenital Abnormalities; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Pregnancy; Pregnancy Outcome; Vitamin B 12 | 2005 |
Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Dietary Supplements; Dose-Response Relationship, Drug; Drug Synergism; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Sex Factors; Vitamin B 12; Vitamin B 6 | 2005 |
[Diagnosis of vitamin B12 deficiency revised].
Topics: Homocysteine; Humans; Methylmalonic Acid; Predictive Value of Tests; Schilling Test; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Are B vitamins a risk factor for VTE? Perhaps.
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Thromboembolism; Venous Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Deficiency | 2006 |
[Oxidative stress in metabolic syndrome and nonalcoholic steatohepatitis. Is it possible a role for vitamins in clinical practice?].
Topics: Adult; Animals; Antioxidants; Cells, Cultured; Clinical Trials as Topic; Endothelial Cells; Fatty Liver; Female; Folic Acid; Hepatitis; Homocysteine; Humans; Insulin Resistance; Male; Metabolic Syndrome; Oxidative Stress; Rats; Risk Factors; Silybin; Silymarin; Time Factors; Vitamin B 12; Vitamin D; Vitamins | 2006 |
Vitamin B12 and methionine synthesis: a critical review. Is nature's most beautiful cofactor misunderstood?
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biological Transport; Bone Marrow; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Myelin Sheath; Nerve Tissue; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
The many facets of hyperhomocysteinemia: studies from the Framingham cohorts.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cardiovascular Diseases; Carotid Stenosis; Cohort Studies; Dementia; Diet; Female; Folic Acid; Fractures, Bone; Heart Failure; Homocysteine; Humans; Hyperhomocysteinemia; Male; Massachusetts; Middle Aged; Risk Factors; Stroke; Vascular Diseases; Vitamin B 12; Vitamin B 6 | 2006 |
Vitamins and minerals 4: overview of folate and the B vitamins.
Topics: Alzheimer Disease; Cardiovascular Diseases; Chemoprevention; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neoplasms; Primary Prevention; Risk Factors; Risk Reduction Behavior; Vitamin B 12; Vitamin B 6 | 2006 |
Biochemistry of homocysteine in health and diseases.
Topics: Animals; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Models, Chemical; Oxidative Stress; Smoking; Thrombosis; Vitamin B 12; Vitamin B 6 | 2006 |
Effects of B-vitamins on plasma homocysteine concentrations and on risk of cardiovascular disease and dementia.
Topics: Cardiovascular Diseases; Confidence Intervals; Dementia; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Humans; Odds Ratio; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12; Vitamin B Complex | 2007 |
Clinical inquiries. How do we evaluate a marginally low B12 level?
Topics: Evaluation Studies as Topic; Evidence-Based Medicine; Family Practice; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Prognosis; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
[Hyperhomocysteinemia in pediatric age and nutritional aspects of folates: an early cardiovascular risk factor].
Topics: Atherosclerosis; Cardiovascular Diseases; Drug Therapy, Combination; Endothelium; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2006 |
Not just calcium and vitamin D: other nutritional considerations in osteoporosis.
Topics: Anorexia Nervosa; Bone Density; Diet; Dietary Supplements; Fruit; Homocysteine; Humans; Nutritional Requirements; Osteoporosis; Randomized Controlled Trials as Topic; Vegetables; Vitamin B 12; Vitamin K | 2007 |
[Risk factors for cardiovascular diseases: what is the role for homocysteine?].
Topics: Cardiovascular Diseases; Folic Acid; Follow-Up Studies; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6 | 2007 |
[The role of homocysteine thiolactone in some of human diseases].
Topics: Animals; Aryldialkylphosphatase; Atherosclerosis; Biomarkers; Fibrinogen; Folic Acid; Homocysteine; Humans; Lipoproteins, HDL; Rabbits; Stroke; Vitamin B 12; Vitamin B 6 | 2006 |
The homocysteine hypothesis of depression.
Topics: Age Factors; Aged; Aged, 80 and over; Cardiovascular Diseases; Child; Comorbidity; Depressive Disorder; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mutation; Neurotransmitter Agents; Stroke; Vitamin B 12; Vitamin B 6 | 2007 |
[Nutritional medicine 2007].
Topics: Cardiovascular Diseases; Diet; Evidence-Based Medicine; Fatty Acids, Omega-3; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Practice Guidelines as Topic; Primary Prevention; Risk Assessment; Stroke; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Homocysteine lowering and cardiovascular disease risk: lost in translation.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Risk Factors; Survival Rate; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Homocysteine and cardiovascular disease: a review of the evidence.
Topics: Biomarkers; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Risk Assessment; Risk Factors; Treatment Outcome; Up-Regulation; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Homocysteine-lowering therapy: a role in stroke prevention?
Topics: Animals; Clinical Trials as Topic; Homocysteine; Humans; Myocardial Infarction; Risk; Stroke; Vitamin B 12; Vitamin B 6 | 2007 |
[Review of the role of hyperhomocysteinemia and B-vitamin deficiency in neurological and psychiatric disorders--current evidence and preliminary recommendations].
Topics: Aged; Central Nervous System; Child; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mental Disorders; Nervous System Diseases; Parkinson Disease; Risk Factors; Vitamin B 12; Vitamin B Deficiency | 2007 |
Biomarkers of folate and vitamin B(12) status in cerebrospinal fluid.
Topics: Biomarkers; Brain; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 2007 |
Homocysteine and cerebral stroke in developing countries.
Topics: Developing Countries; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Networks and Pathways; Nutritional Status; Stroke; Vitamin B 12 | 2007 |
[Homocysteine metabolism].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Cardiovascular Diseases; Deuterium; Gas Chromatography-Mass Spectrometry; Gout; Homocysteine; Humans; Hyperhomocysteinemia; Isotope Labeling; Methionine; Oxidation-Reduction; Risk Factors; Serum Albumin; Vitamin B 12 | 2007 |
Homocysteine, vitamins, and vascular disease prevention.
Topics: Aged; Atherosclerosis; Dietary Supplements; Folic Acid; Homocysteine; Humans; Vascular Diseases; Vitamin B 12; Vitamin B 6 | 2007 |
Vitamins and stroke: the homocysteine hypothesis still in doubt.
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Dietary Supplements; Folic Acid; Homocysteine; Humans; Intracranial Arteriosclerosis; Stroke; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2008 |
[Should patients with chronic renal insufficiency be treated with folic acid, vitamin B6 and vitamin B12?].
Topics: Drug Therapy, Combination; Evidence-Based Medicine; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Renal Insufficiency, Chronic; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
[Biochemical alterations in patients with Down syndrome].
Topics: Acetylglucosaminidase; Adult; Alzheimer Disease; Antioxidants; Bilirubin; Blood Proteins; Cystathionine beta-Synthase; Disease Progression; Down Syndrome; Ferritins; Folic Acid; Homocysteine; Humans; Learning; Nootropic Agents; Quality of Life; S100 Proteins; Serum Albumin; Superoxide Dismutase; Transferrin; Vitamin B 12 | 2008 |
Intake and status of folate and related B-vitamins: considerations and challenges in achieving optimal status.
Topics: Adult; Aged; Biomarkers; Diet; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Nutritional Requirements; Nutritional Status; Riboflavin; Vitamin B 12; Vitamin B 6; Vitamins | 2008 |
Indicators for assessing folate and vitamin B12 status and for monitoring the efficacy of intervention strategies.
Topics: Biomarkers; Diagnosis, Differential; Erythrocyte Indices; Erythrocytes; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Nutrition Assessment; Nutritional Status; Sensitivity and Specificity; Sentinel Surveillance; Transcobalamins; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
The use of blood concentrations of vitamins and their respective functional indicators to define folate and vitamin B12 status.
Topics: Biomarkers; Erythrocytes; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Methylmalonic Acid; Nutrition Assessment; Nutritional Status; Reference Standards; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Public health significance of elevated homocysteine.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Dementia; Diet; Female; Folic Acid; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neural Tube Defects; Pregnancy; Public Health; Risk Factors; Vitamin B 12; Vitamin B 6 | 2008 |
The worldwide challenge of the dementias: a role for B vitamins and homocysteine?
Topics: Aged; Aged, 80 and over; Aging; Dementia; Environment; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12; Vitamin B Complex | 2008 |
The effect of long-term homocysteine-lowering on carotid intima-media thickness and flow-mediated vasodilation in stroke patients: a randomized controlled trial and meta-analysis.
Topics: Aged; Carotid Arteries; Dietary Supplements; Double-Blind Method; Down-Regulation; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Regional Blood Flow; Stroke; Time Factors; Treatment Outcome; Tunica Intima; Tunica Media; Vasodilation; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Homocysteine and depression in later life.
Topics: Age Factors; Aged; Cohort Studies; Depressive Disorder; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Personality Inventory; Polymorphism, Genetic; Pyridoxine; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12 | 2008 |
[Present role of homocysteine in clinical medicine].
Topics: Adolescent; Adult; Cardiovascular Diseases; Child; Child, Preschool; Ectopia Lentis; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Life Style; Male; Middle Aged; Myopia; Pregnancy; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
Homocysteine as a risk factor for cardiovascular disease in patients treated by dialysis: a meta-analysis.
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Prospective Studies; Renal Dialysis; Retrospective Studies; Risk Factors; Vitamin B 12 | 2009 |
[Does diet affect our mood? The significance of folic acid and homocysteine].
Topics: Affect; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Mood Disorders; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2009 |
Studies of biomarker responses to intervention with vitamin B-12: a systematic review of randomized controlled trials.
Topics: Biomarkers; Dietary Supplements; Homocysteine; Humans; Methylmalonic Acid; Nutrition Assessment; Nutritional Status; Randomized Controlled Trials as Topic; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2009 |
Cobalamin, folic acid, and homocysteine.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Neural Tube Defects; Nutritional Requirements; Nutritional Status; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2009 |
Homocysteine, vitamin B12, folate and cognitive functions: a systematic and critical review of the literature.
Topics: Adult; Clinical Trials as Topic; Cognition Disorders; Cross-Sectional Studies; Dietary Supplements; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2009 |
Alterations in homocysteine metabolism among alcohol dependent patients--clinical, pathobiochemical and genetic aspects.
Topics: Alcohol Withdrawal Seizures; Alcoholism; Alleles; DNA Methylation; Dopamine; Epigenesis, Genetic; Ethanol; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Methylenetetrahydrofolate Dehydrogenase (NADP); Myocardial Infarction; Polymorphism, Single Nucleotide; Receptors, N-Methyl-D-Aspartate; Reward; Risk Factors; Social Environment; Vitamin B 12; Vitamin B 6 | 2008 |
Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.
Topics: Adult; Chromosomes, Human; DNA-Binding Proteins; Female; Folic Acid; Genome-Wide Association Study; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Transcription Factors; Vitamin B 12 | 2009 |
[Hyperhomocysteinemia and cardiometabolic risk].
Topics: Biomarkers; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Deficiency; Vitamins | 2009 |
Homocysteine, folate and vitamin B12 in neuropsychiatric diseases: review and treatment recommendations.
Topics: Folic Acid; Homocysteine; Humans; Mental Disorders; Nervous System Diseases; Vitamin B 12 | 2009 |
Genetics of homocysteine metabolism and associated disorders.
Topics: Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Methylenetetrahydrofolate Dehydrogenase (NAD+); Severity of Illness Index; Vitamin B 12; Vitamin B 6 | 2010 |
L-methylfolate, methylcobalamin, and N-acetylcysteine in the treatment of Alzheimer's disease-related cognitive decline.
Topics: Acetylcysteine; Alzheimer Disease; Cognition Disorders; Free Radical Scavengers; Homocysteine; Humans; Oxidative Stress; Plaque, Amyloid; Tetrahydrofolates; Vitamin B 12; Vitamin B Complex | 2010 |
Efficacy of homocysteine-lowering therapy with folic Acid in stroke prevention: a meta-analysis.
Topics: Female; Folic Acid; Homocysteine; Humans; Male; Randomized Controlled Trials as Topic; Risk Factors; Sex Factors; Stroke; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2010 |
Circulating folate, vitamin B12, homocysteine, vitamin B12 transport proteins, and risk of prostate cancer: a case-control study, systematic review, and meta-analysis.
Topics: Aged; Case-Control Studies; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Prostatic Neoplasms; Risk Factors; Transcobalamins; Vitamin B 12 | 2010 |
Is a low blood level of vitamin B12 a cardiovascular and diabetes risk factor? A systematic review of cohort studies.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Meta-Analysis as Topic; Risk Factors; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Cobalamin C defect: natural history, pathophysiology, and treatment.
Topics: Age of Onset; Homocysteine; Humans; Methionine; Methylmalonic Acid; Models, Biological; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Combined analyses and extended follow-up of two randomized controlled homocysteine-lowering B-vitamin trials.
Topics: Capsules; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Myocardial Ischemia; Patient Compliance; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2010 |
B vitamins and the aging brain.
Topics: Aged; Aging; Brain; Cognition Disorders; Homocysteine; Humans; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Complex | 2010 |
Chemistry behind Vegetarianism.
Topics: Atherosclerosis; Biochemical Phenomena; Diet, Vegetarian; Fatty Acids, Omega-3; Homocysteine; Humans; Nutritional Status; Nutritive Value; Platelet Aggregation; Risk Factors; Thrombosis; Vitamin B 12; Vitamin D; Zinc | 2011 |
Biomarkers of cobalamin (vitamin B12) deficiency and its application.
Topics: Aging; Biomarkers; Cognition Disorders; Erythrocyte Indices; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Meta-analysis of the relationship between homocysteine, vitamin B₁₂, folate, and multiple sclerosis.
Topics: Folic Acid; Homocysteine; Humans; Multiple Sclerosis; Vitamin B 12 | 2011 |
Holotranscobalamin, a marker of vitamin B-12 status: analytical aspects and clinical utility.
Topics: Biomarkers; Circadian Rhythm; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Overview of a roundtable on NHANES monitoring of biomarkers of folate and vitamin B-12 status: measurement procedure issues.
Topics: Biomarkers; Chromatography, Liquid; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Nutrition Surveys; Tandem Mass Spectrometry; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Folate and vitamin B-12 biomarkers in NHANES: history of their measurement and use.
Topics: Bias; Biomarkers; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Nutrition Surveys; Public Policy; Vitamin B 12 | 2011 |
Biomarkers of cobalamin (vitamin B-12) status in the epidemiologic setting: a critical overview of context, applications, and performance characteristics of cobalamin, methylmalonic acid, and holotranscobalamin II.
Topics: Biomarkers; Homocysteine; Humans; Methylmalonic Acid; Public Health; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Biomarkers of vitamin B-12 status in NHANES: a roundtable summary.
Topics: Biomarkers; Cognition Disorders; Homocysteine; Humans; Methylmalonic Acid; Nutrition Surveys; Public Health; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Is high homocysteine level a risk factor for cognitive decline in elderly? A systematic review, meta-analysis, and meta-regression.
Topics: Aged; Alzheimer Disease; Dementia; Dementia, Vascular; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Regression Analysis; Risk Factors; Vitamin B 12 | 2011 |
Plasma homocysteine, serum folic acid, serum vitamin B12, serum vitamin B6, MTHFR and risk of pseudoexfoliation glaucoma: a meta-analysis.
Topics: Aged; Exfoliation Syndrome; Folic Acid; Genotype; Glaucoma, Open-Angle; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2012 |
Chemical pathology of homocysteine. V. Thioretinamide, thioretinaco, and cystathionine synthase function in degenerative diseases.
Topics: Cystathionine beta-Synthase; Disease; Homocysteine; Humans; Oxidation-Reduction; Tretinoin; Vitamin B 12 | 2011 |
Effect of homocysteine lowering treatment on cognitive function: a systematic review and meta-analysis of randomized controlled trials.
Topics: Cognition Disorders; Dietary Supplements; Folic Acid; Homocysteine; Humans; Randomized Controlled Trials as Topic; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2012 |
Methionine, homocysteine, one carbon metabolism and fetal growth.
Topics: Adult; Animals; Carbon; Dietary Proteins; Energy Intake; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Methionine; Pregnancy; Rats; Vitamin B 12; Vitamins | 2012 |
Leukoencephalopathies associated with disorders of cobalamin and folate metabolism.
Topics: Cobamides; Folic Acid; Homocysteine; Humans; Infant, Newborn; Leukoencephalopathies; Neonatal Screening; Tetrahydrofolates; Vitamin B 12 | 2012 |
[Homocysteine, vitamin B-12, folic acid and the cognitive decline in the elderly].
Topics: Aged; Brain; Cognition Disorders; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nutritional Physiological Phenomena; Receptors, N-Methyl-D-Aspartate; Risk Factors; Vitamin B 12 | 2013 |
The role of B vitamins in preventing and treating cognitive impairment and decline.
Topics: Alzheimer Disease; Cognition; Cognition Disorders; Folic Acid; Homocysteine; Humans; Methylation; Vitamin B 12; Vitamin B Complex; Vitamin B Deficiency | 2012 |
Role of heat-shock proteins and cobalamine in maintaining methionine synthase activity.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Heat-Shock Proteins; Homocysteine; Humans; Kinetics; Metabolic Networks and Pathways; Methionine; Methylation; Plaque, Atherosclerotic; Vitamin B 12 | 2012 |
Plasma total homocysteine status of vegetarians compared with omnivores: a systematic review and meta-analysis.
Topics: Adult; Cohort Studies; Cross-Sectional Studies; Diet; Diet, Vegetarian; Dietary Supplements; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Clinical practice. Vitamin B12 deficiency.
Topics: Administration, Oral; Anemia, Pernicious; Child; Child Nutrition Disorders; Diagnostic Errors; Female; Homocysteine; Humans; Infant; Infant Nutrition Disorders; Injections; Intestinal Absorption; Methylmalonic Acid; Middle Aged; Paresthesia; Practice Guidelines as Topic; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Folate and B12 in prostate cancer.
Topics: Betaine; Diet; Dietary Supplements; Folic Acid; Homocysteine; Humans; Male; Meta-Analysis as Topic; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors; Vitamin B 12 | 2013 |
A focus on homocysteine in autism.
Topics: Animals; Autistic Disorder; Avitaminosis; Body Fluids; Cystathionine beta-Synthase; Diet; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12; Vitamin B 6 | 2013 |
Effect of B vitamins and lowering homocysteine on cognitive impairment in patients with previous stroke or transient ischemic attack: a prespecified secondary analysis of a randomized, placebo-controlled trial and meta-analysis.
Topics: Aged; Cognition Disorders; Double-Blind Method; Female; Follow-Up Studies; Homocysteine; Humans; Ischemic Attack, Transient; Male; Middle Aged; Placebos; Recurrence; Stroke; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2013 |
Vitamin B12, folic acid, and bone.
Topics: Bone and Bones; Bone Density; Dietary Supplements; Folic Acid; Fractures, Bone; Homocysteine; Humans; Prevalence; Vitamin B 12 | 2013 |
[Advances in the clinical and laboratory studies on methylmalonic aciduria combined with homocysteinemia type cblC].
Topics: Adult; Age of Onset; Amino Acid Metabolism, Inborn Errors; Betaine; Carrier Proteins; Child; China; DNA Mutational Analysis; Gas Chromatography-Mass Spectrometry; Genotype; Homocysteine; Humans; Hydroxocobalamin; Hyperhomocysteinemia; Infant; Methylmalonic Acid; Mutation; Oxidoreductases; Vitamin B 12 | 2013 |
The role of folic acid fortification in neural tube defects: a review.
Topics: Biological Availability; Choline; Edible Grain; Female; Folic Acid; Folic Acid Antagonists; Food, Fortified; Homocysteine; Humans; Neural Tube Defects; Nutritional Requirements; Pregnancy; Recommended Dietary Allowances; United States; Vitamin B 12 | 2013 |
Vitamin B(12) metabolism during pregnancy and in embryonic mouse models.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Acyl Coenzyme A; Animals; Disease Models, Animal; Embryonic Development; Female; Homocysteine; Humans; Methionine; Methylmalonyl-CoA Mutase; Mice; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Neural tube defects, folic acid and methylation.
Topics: Animals; Choline; Folic Acid; Homocysteine; Humans; Methylation; Neural Tube Defects; Neurulation; Vitamin B 12; Vitamin B Complex | 2013 |
Association of homocysteine, vitamin B12, and folate with bone mineral density in postmenopausal women: a meta-analysis.
Topics: Bone Density; Case-Control Studies; China; Cohort Studies; Confidence Intervals; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Osteoporosis, Postmenopausal; Postmenopause; Vitamin B 12 | 2014 |
The role of the one-carbon cycle in the developmental origins of Type 2 diabetes and obesity.
Topics: Adiposity; Carbon Cycle; Diabetes Mellitus, Type 2; Environmental Exposure; Female; Fetal Development; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant, Newborn; Insulin Resistance; Male; Maternal Nutritional Physiological Phenomena; Methylmalonic Acid; Obesity; Pregnancy; Prenatal Exposure Delayed Effects; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Neuroenhancement with vitamin B12-underestimated neurological significance.
Topics: Alzheimer Disease; Brain; Cognition; Homocysteine; Humans; Incidence; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2013 |
Vitamin B12 and cognitive function: an evidence-based analysis.
Topics: Blood Chemical Analysis; Cognition; Cognitive Dysfunction; Dementia; Dietary Supplements; Evidence-Based Practice; Homocysteine; Humans; Injections, Intramuscular; Longitudinal Studies; Ontario; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Research Design; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2013 |
Lifetime requirement of the methionine cycle for neuronal development and maintenance.
Topics: Developmental Disabilities; Female; Folic Acid; Homocysteine; Humans; Methionine; Pregnancy; Prenatal Care; S-Adenosylmethionine; Vitamin B 12; Vitamin B Complex | 2014 |
Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke.
Topics: Aldehyde Dehydrogenase; Carbon; Folic Acid; Genome-Wide Association Study; Genotype; Homocysteine; Humans; Methionine; Oxidoreductases Acting on CH-NH Group Donors; Stroke; Vitamin B 12 | 2014 |
[Hyperhomocysteinemia in patients with cardiovascular disease].
Topics: Cardiovascular Diseases; Causality; Comorbidity; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Myocardial Infarction; Risk Factors; Vitamin B 12 | 2014 |
The MTRR 66A>G polymorphism and maternal risk of birth of a child with Down syndrome in Caucasian women: a case-control study and a meta-analysis.
Topics: Adult; Aged; Alleles; Biomarkers; Case-Control Studies; Down Syndrome; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Genotyping Techniques; Heterozygote; Homocysteine; Humans; Logistic Models; Middle Aged; Mothers; Polymorphism, Single Nucleotide; Risk Factors; Vitamin B 12; White People | 2014 |
Vitamin B12 deficiency.
Topics: Homocysteine; Humans; Hydroxocobalamin; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2014 |
The effect of folate fortification on folic acid-based homocysteine-lowering intervention and stroke risk: a meta-analysis.
Topics: Databases, Factual; Folic Acid; Food, Fortified; Homocysteine; Humans; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Vitamin B 12 | 2015 |
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: epidemiology, metabolism and the associated diseases.
Topics: Diabetes Mellitus; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Infertility; Mental Disorders; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Nervous System Diseases; Polymorphism, Genetic; Psoriasis; Vascular Diseases; Vitamin B 12 | 2015 |
Quantitative assessment of maternal biomarkers related to one-carbon metabolism and neural tube defects.
Topics: Biomarkers; Carbon; Case-Control Studies; Confidence Intervals; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Neural Tube Defects; Vitamin B 12 | 2015 |
Vitamin supplementation as possible prophylactic treatment against migraine with aura and menstrual migraine.
Topics: Adult; Ascorbic Acid; Epilepsy; Female; Folic Acid; Genotype; Homocysteine; Humans; Menstruation; Migraine Disorders; Migraine with Aura; Vitamin B 12; Vitamin B 6; Vitamin E | 2015 |
Associations between Homocysteine, Folic Acid, Vitamin B12 and Alzheimer's Disease: Insights from Meta-Analyses.
Topics: Age Factors; Alzheimer Disease; Databases, Bibliographic; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12 | 2015 |
Plasma Homocysteine, Serum Folic Acid, Serum Vitamin B12, Serum Vitamin B6, MTHFR, and Risk of Normal-Tension Glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Folic Acid; Genotype; Homocysteine; Humans; Intraocular Pressure; Low Tension Glaucoma; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamins | 2016 |
Effect of Vitamin Intake on Cognitive Decline in Older Adults: Evaluation of the Evidence.
Topics: Aged; Antioxidants; Ascorbic Acid; beta Carotene; Cognition; Cognition Disorders; Dementia; Dietary Supplements; Folic Acid; Homocysteine; Humans; Meta-Analysis as Topic; Vitamin A; Vitamin B 12; Vitamin B 6; Vitamin D; Vitamin D Deficiency; Vitamin E; Vitamins | 2015 |
Homocysteine and the risk of age-related macular degeneration: a systematic review and meta-analysis.
Topics: Aged; Aged, 80 and over; Female; Folic Acid; Homocysteine; Humans; Macular Degeneration; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2015 |
Early pregnancy B vitamin status, one carbon metabolism, pregnancy outcome and child development.
Topics: Betaine; Carbon; Child; Child Development; Child, Preschool; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Pregnancy; Pregnancy Trimester, Third; Sarcosine; Vitamin B 12 | 2016 |
One carbon metabolism and bone homeostasis and remodeling: A review of experimental research and population studies.
Topics: Animals; Bone and Bones; Bone Remodeling; Carbon; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Osteoblasts; Osteoclasts; Vitamin B 12; Vitamin B Deficiency | 2016 |
Interventions for lowering plasma homocysteine levels in dialysis patients.
Topics: Aged; Cardiovascular Diseases; Cause of Death; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Infarction; Renal Dialysis; Stroke; Venous Thrombosis; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2016 |
Maternal biomarkers of methylation status and non-syndromic orofacial cleft risk: a meta-analysis.
Topics: Biomarkers; Cleft Lip; Cleft Palate; Female; Folic Acid; Homocysteine; Humans; Methylation; Pregnancy; Vitamin B 12 | 2016 |
Homocysteine, B Vitamins, and Cognitive Impairment.
Topics: Aging; Animals; Biomarkers; Cerebrovascular Circulation; Cognition Disorders; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nootropic Agents; Nutritional Status; Practice Guidelines as Topic; Risk Factors; Vitamin B 12; Vitamin B 6 | 2016 |
[Meta-analysis on effect of combined supplementation of folic acid, vitamin B12 and B6 on risk of cardio-cerebrovascular diseases in randomized control trials].
Topics: Adult; Aged; Cardiovascular Diseases; Dietary Supplements; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Incidence; Middle Aged; Randomized Controlled Trials as Topic; Risk; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2016 |
Homocysteine and cognition: A systematic review of 111 studies.
Topics: Cognition; Cognition Disorders; Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 2016 |
Association of plasma homocysteine, vitamin B12 and folate levels with cognitive function in Parkinson's disease: A meta-analysis.
Topics: Adult; Aged; Aged, 80 and over; Cognition; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Treatment Outcome; Vitamin B 12 | 2017 |
Guidelines for diagnosis and management of the cobalamin-related remethylation disorders cblC, cblD, cblE, cblF, cblG, cblJ and MTHFR deficiency.
Topics: Animals; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Proto-Oncogene Proteins c-cbl; Vitamin B 12 | 2017 |
Oxcarbazepine administration and the serum levels of homocysteine, vitamin B12 and folate in epileptic patients: A systematic review and meta-analysis.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Folic Acid; Homocysteine; Humans; Oxcarbazepine; Vitamin B 12 | 2017 |
Hypermethylation: Causes and Consequences in Skeletal Muscle Myopathy.
Topics: Animals; DNA Methylation; Epigenesis, Genetic; Folic Acid; Histones; Homocysteine; Humans; Hyperhomocysteinemia; Metformin; Muscle, Skeletal; Muscular Diseases; Oxidative Stress; RNA Interference; Thiazolidinediones; Vitamin B 12; Vitamin B 6 | 2017 |
Implication of homocysteine in diabetes and impact of folate and vitamin B12 in diabetic population.
Topics: Diabetes Mellitus; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Prevalence; Vitamin B 12 | 2017 |
Efficacy of Vitamin B Supplementation on Cognition in Elderly Patients With Cognitive-Related Diseases.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cognition Disorders; Dementia; Dietary Supplements; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2017 |
Vitamin B
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Child; Child, Preschool; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Prevalence; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2017 |
Association of
Topics: Adult; Aged; Alleles; Alzheimer Disease; Carbon; Child; Congenital Abnormalities; Female; Genotype; Homocysteine; Humans; Male; Methylmalonic Acid; Neoplasms; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; White People | 2017 |
Vitamin B12, folate, and homocysteine levels and multiple sclerosis: A meta-analysis.
Topics: Folic Acid; Homocysteine; Humans; Multiple Sclerosis; Vitamin B 12 | 2017 |
Atypical hemolytic uremic syndrome induced by CblC subtype of methylmalonic academia: A case report and literature review.
Topics: Amino Acid Metabolism, Inborn Errors; Atypical Hemolytic Uremic Syndrome; Carrier Proteins; Child, Preschool; Female; Homocysteine; Humans; Kidney; Methylmalonic Acid; Mutation; Oxidoreductases; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2017 |
Homocysteine and Hyperhomocysteinaemia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Avitaminosis; Cystathionine beta-Synthase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12; Vitamin B 6 | 2019 |
Proton Pump Inhibitors, H2-Receptor Antagonists, Metformin, and Vitamin B-12 Deficiency: Clinical Implications.
Topics: Histamine H2 Antagonists; Homocysteine; Humans; Metformin; Methylmalonic Acid; Nutritional Status; Proton Pump Inhibitors; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Serum homocysteine, folate and vitamin B
Topics: Biomarkers; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Psoriasis; Vitamin B 12 | 2019 |
A systematic review of the vitamin B12, folate and homocysteine triad across body mass index.
Topics: Body Mass Index; Folic Acid; Homocysteine; Humans; Obesity; Vitamin B 12 | 2018 |
Serum homocysteine, folate, and vitamin B
Topics: Biomarkers; Case-Control Studies; Folic Acid; Homocysteine; Humans; Severity of Illness Index; Vitamin B 12; Vitiligo | 2019 |
Folate, vitamin B12, and homocysteine in smoking-exposed pregnant women: A systematic review.
Topics: Female; Folic Acid; Homocysteine; Humans; Maternal Exposure; Mothers; Pregnancy; Pregnancy Complications; Smoking; Smoking Cessation; Vitamin B 12 | 2019 |
Homocysteine Modification in Protein Structure/Function and Human Disease.
Topics: Animals; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12 | 2019 |
Targeting MTHFR for the treatment of migraines.
Topics: Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Migraine Disorders; Molecular Targeted Therapy; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6 | 2019 |
The Controversial Role of Homocysteine in Neurology: From Labs to Clinical Practice.
Topics: Animals; Homocysteine; Humans; Inflammation; Neurology; Practice Patterns, Physicians'; Reactive Oxygen Species; Vitamin B 12 | 2019 |
Folic Acid and Vitamin B12 Administration in CKD, Why Not?
Topics: Biomarkers; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Risk Factors; Vitamin B 12 | 2019 |
Effects of phenytoin on serum levels of homocysteine, vitamin B12, folate in patients with epilepsy: A systematic review and meta-analysis (PRISMA-compliant article).
Topics: Anticonvulsants; Epilepsy; Folic Acid; Homocysteine; Humans; Phenytoin; Research Design; Vitamin B 12 | 2019 |
Effect of Vitamin B Supplementation on Cognitive Function in the Elderly: A Systematic Review and Meta-Analysis.
Topics: Aged; Cognition; Cognition Disorders; Dementia; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2019 |
Implication of homocysteine in protein quality control processes.
Topics: Animals; Apoptosis; Autophagy; Cell Line; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Molecular Chaperones; Protein Aggregation, Pathological; Protein Processing, Post-Translational; Rats; Ubiquitination; Unfolded Protein Response; Vitamin B 12 | 2019 |
Homocysteine, folic acid, and vitamin B12 levels in patients on isotretinoin therapy for acne vulgaris: A meta-analysis.
Topics: Acne Vulgaris; Administration, Oral; Folic Acid; Homocysteine; Humans; Isotretinoin; Vitamin B 12 | 2020 |
The effects of isotretinoin therapy on serum homocysteine, folate and vitamin B
Topics: Acne Vulgaris; Folic Acid; Homocysteine; Humans; Isotretinoin; Vitamin B 12 | 2020 |
Chemical Pathology of Homocysteine VII. Cholesterol, Thioretinaco Ozonide, Mitochondrial Dysfunction, and Prevention of Mortality.
Topics: Cholesterol; Homocysteine; Humans; Mitochondria; Mortality; Oxidative Phosphorylation; Vitamin B 12 | 2019 |
Homocysteine, vitamin B12, and folate levels in patients with multiple sclerosis in Chinese population: A case-control study and meta-analysis.
Topics: Adult; Case-Control Studies; China; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multiple Sclerosis; Vitamin B 12 | 2019 |
Homocysteine and psoriasis.
Topics: Animals; Cytokines; Folic Acid; Homocysteine; Humans; Inflammation; Psoriasis; Vitamin B 12 | 2019 |
Plasma homocysteine, folate and vitamin B12 levels in Parkinson's disease in China: A meta-analysis.
Topics: Case-Control Studies; China; Folic Acid; Homocysteine; Humans; Parkinson Disease; Vitamin B 12 | 2020 |
Serum levels of Homocysteine, Vitamin B12 and Folate in Patients with Multiple Sclerosis: an Updated Meta-Analysis.
Topics: Adult; Case-Control Studies; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Multiple Sclerosis; Vitamin B 12 | 2020 |
Genetic, epigenetic and genomic mechanisms of methionine dependency of cancer and tumor-initiating cells: What could we learn from folate and methionine cycles.
Topics: Cell Line, Tumor; Epigenesis, Genetic; Folic Acid; Homocysteine; Humans; Methionine; Neoplasms; Neoplastic Stem Cells; Vitamin B 12 | 2020 |
Environmental Pollution, Oxidative Stress and Thioretinaco Ozonide: Effects of Glyphosate, Fluoride and Electromagnetic Fields on Mitochondrial Dysfunction in Carcinogenesis, Atherogenesis and Aging.
Topics: Aging; Animals; Atherosclerosis; Carcinogenesis; Electromagnetic Fields; Environmental Pollution; Fluorides; Glycine; Glyphosate; Homocysteine; Humans; Hyperhomocysteinemia; Mitochondria; Neoplasms; Oxidative Phosphorylation; Oxidative Stress; Vitamin B 12 | 2020 |
Serum Homocysteine, Pyridoxine, Folate, and Vitamin B12 Levels in Migraine: Systematic Review and Meta-Analysis.
Topics: Folic Acid; Homocysteine; Humans; Migraine with Aura; Migraine without Aura; Pyridoxine; Vitamin B 12 | 2020 |
Serum Homocysteine, Folate, and Vitamin B
Topics: Adult; Folic Acid; Homocysteine; Humans; Lupus Erythematosus, Systemic; Vitamin B 12; Vitamins | 2021 |
Association between abnormal maternal serum levels of vitamin B12 and preeclampsia: a systematic review and meta-analysis.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Observational Studies as Topic; Pre-Eclampsia; Pregnancy; Vitamin B 12; Young Adult | 2021 |
Utilization of B12 for the treatment of chronic migraine.
Topics: Chronic Disease; Homocysteine; Humans; Migraine Disorders; Nitric Oxide; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2020 |
Chemical Pathology of Homocysteine VIII. Effects of Tocotrienol, Geranylgeraniol, and Squalene on Thioretinaco Ozonide, Mitochondrial Permeability, and Oxidative Phosphorylation in Arteriosclerosis, Cancer, Neurodegeneration and Aging.
Topics: Aging; Animals; Arteriosclerosis; Cholesterol; Diterpenes; Homocysteine; Humans; Mitochondria; NAD; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Phosphorylation; Permeability; Squalene; Tocotrienols; Vitamin B 12 | 2020 |
Reducing the Risk of Stroke in Patients with Impaired Renal Function: Nutritional Issues.
Topics: Bacteria; Biomarkers; Comorbidity; Diet; Dietary Supplements; Gastrointestinal Microbiome; Homocysteine; Humans; Kidney; Nutritional Status; Protective Factors; Renal Insufficiency; Risk Assessment; Risk Factors; Stroke; Treatment Outcome; Uremia; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
Epigenetic factors in atherosclerosis: DNA methylation, folic acid metabolism, and intestinal microbiota.
Topics: Atherosclerosis; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gastrointestinal Microbiome; Homocysteine; Humans; Vitamin B 12 | 2021 |
COVID-19's toll on the elderly and those with diabetes mellitus - Is vitamin B12 deficiency an accomplice?
Topics: Aged; Comorbidity; COVID-19; Critical Care; Diabetes Complications; Folic Acid Deficiency; Gastrointestinal Microbiome; Homocysteine; Humans; Models, Biological; Obesity; Pandemics; Risk Factors; SARS-CoV-2; Severity of Illness Index; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
Homocysteine and diabetes: Role in macrovascular and microvascular complications.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Diabetic Nephropathies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12 | 2021 |
Association between neuropathy and B-vitamins: A systematic review and meta-analysis.
Topics: Dietary Supplements; Folic Acid; Homocysteine; Humans; Peripheral Nervous System Diseases; Vitamin B 12; Vitamin B Complex | 2021 |
The role of B vitamins in stroke prevention.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Vitamin B 12; Vitamin B Complex | 2022 |
Serum Vitamins and Homocysteine Levels in Obsessive-Compulsive Disorder: A Systematic Review and Meta-Analysis.
Topics: Folic Acid; Homocysteine; Humans; Obsessive-Compulsive Disorder; Vitamin B 12; Vitamins | 2021 |
A Novel Review of Homocysteine and Pregnancy Complications.
Topics: Abortion, Habitual; Aging; Birth Weight; Diabetes, Gestational; Dietary Supplements; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2021 |
Hyperhomocysteinemia and low vitamin B12 are associated with the risk of early pregnancy loss: A clinical study and meta-analyses.
Topics: Abortion, Spontaneous; Adult; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Maternal Nutritional Physiological Phenomena; Meta-Analysis as Topic; Nutritional Status; Odds Ratio; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2021 |
[Increased plasma levels of vitamin B12].
Topics: Folic Acid; Homocysteine; Humans; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
The link between homocysteine, folic acid and vitamin B12 in chronic kidney disease.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Renal Dialysis; Vitamin B 12 | 2021 |
Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
Topics: Aged; Bone Density; Dietary Supplements; Eating; Female; Folic Acid; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B Complex | 2022 |
Vitamin B12 and gut-brain homeostasis in the pathophysiology of ischemic stroke.
Topics: Animals; Biomarkers; Brain-Gut Axis; Disease Susceptibility; Dysbiosis; Gastrointestinal Microbiome; Homocysteine; Humans; Ischemic Stroke; Metabolic Networks and Pathways; Neuroinflammatory Diseases; Risk Factors; Translational Research, Biomedical; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
The role of vitamin B12 in viral infections: a comprehensive review of its relationship with the muscle-gut-brain axis and implications for SARS-CoV-2 infection.
Topics: Brain-Gut Axis; COVID-19; Dietary Supplements; Folic Acid; Homocysteine; Humans; Muscles; SARS-CoV-2; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Methylenetetrahydrofolate (MTHFR), the One-Carbon Cycle, and Cardiovascular Risks.
Topics: Carbon Cycle; Cardiovascular Diseases; Diabetes Mellitus; Epigenesis, Genetic; Female; Folic Acid; Heart Disease Risk Factors; Homocysteine; Humans; Inflammation; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Vascular Diseases; Vitamin B 12 | 2021 |
Vitamin B-related Gene Polymorphisms and Cardiovascular Disease.
Topics: Aminohydrolases; Cardiovascular Diseases; Folic Acid; Formate-Tetrahydrofolate Ligase; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Multienzyme Complexes; Neoplasm Proteins; Polymorphism, Genetic; Receptors, Cell Surface; Vitamin B 12; Vitamin B Complex | 2022 |
The Controversial Role of HCY and Vitamin B Deficiency in Cardiovascular Diseases.
Topics: Aged; Cardiovascular Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B Complex; Vitamin B Deficiency | 2022 |
COVID-19 and One-Carbon Metabolism.
Topics: Carbon; COVID-19; Folic Acid; Homocysteine; Humans; Methionine; Post-Acute COVID-19 Syndrome; SARS-CoV-2; Vitamin B 12 | 2022 |
Review article: Clinical manifestations and outcomes of chronic nitrous oxide misuse: A systematic review.
Topics: Homocysteine; Humans; Methylmalonic Acid; Nitrous Oxide; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Problem in the Recent American Heart Association Guideline on Secondary Stroke Prevention: B Vitamins to Lower Homocysteine Do Prevent Stroke.
Topics: American Heart Association; Folic Acid; Homocysteine; Humans; Stroke; Vitamin B 12; Vitamin B Complex | 2022 |
B vitamins and homocysteine as determinants of bone health: A literature review of human studies.
Topics: Bone and Bones; Bone Density; Folic Acid; Fractures, Bone; Homocysteine; Humans; Osteoporosis; Vitamin B 12; Vitamin B Complex | 2023 |
B vitamins, polycystic ovary syndrome, and fertility.
Topics: Female; Fertility; Folic Acid; Homocysteine; Humans; Polycystic Ovary Syndrome; Vitamin B 12; Vitamin B Complex | 2022 |
Homocysteine levels, genetic background, and cognitive impairment in Parkinson's disease.
Topics: Case-Control Studies; Cognitive Dysfunction; Folic Acid; Genetic Background; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Parkinson Disease; Vitamin B 12 | 2023 |
Hyperhomocysteinemia in Cardiovascular Diseases: Revisiting Observational Studies and Clinical Trials.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12 | 2023 |
High Folate, Perturbed One-Carbon Metabolism and Gestational Diabetes Mellitus.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Carbon; Choline; Diabetes, Gestational; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Micronutrients; Neural Tube Defects; Pregnancy; Thymidylate Synthase; Vitamin B 12 | 2022 |
The efficacy of vitamin B
Topics: Diabetes Mellitus, Type 2; Dietary Supplements; Homocysteine; Humans; Hypoglycemic Agents; Metformin; Peripheral Nervous System Diseases; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
Levodopa, homocysteine and Parkinson's disease: What's the problem?
Topics: Antiparkinson Agents; Catechol O-Methyltransferase; Homocysteine; Humans; Levodopa; Parkinson Disease; Vitamin B 12; Vitamin B Complex | 2023 |
Homocysteine, vitamin B metabolites, dopamine-substituting compounds, and symptomatology in Parkinson's disease: clinical and therapeutic considerations.
Topics: Antiparkinson Agents; Catechol O-Methyltransferase; Dopamine; Homocysteine; Humans; Levodopa; Parkinson Disease; Vitamin B 12; Vitamins | 2023 |
Features of Plasma Homocysteine, Vitamin B12, and Folate in Parkinson's Disease: An Updated Meta-Analysis.
Topics: Cognitive Dysfunction; Folic Acid; Homocysteine; Humans; Parkinson Disease; Vitamin B 12 | 2023 |
Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis.
Topics: Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Metabolic Syndrome; Vitamin B 12 | 2023 |
Homocysteine as a predictor and prognostic marker of atherosclerotic cardiovascular disease: a systematic review and meta-analysis.
Topics: Aged; Atherosclerosis; Cardiovascular Diseases; Carotid Intima-Media Thickness; Child; Endothelial Cells; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prognosis; Risk Factors; Vitamin B 12 | 2023 |
378 trial(s) available for homocysteine and vitamin b 12
| Article | Year |
|---|---|
[Therapeutic effect of a pharmacologic combination of choleretics and digestive enzymes in exocrine pancreatic insufficiency].
Topics: Adolescent; Adult; Aged; Amylases; Celiac Disease; Cholagogues and Choleretics; Choline; Clinical Trials as Topic; Crohn Disease; Drug Combinations; Drug Evaluation; Female; Gastroenteritis; Homocysteine; Humans; Male; Middle Aged; Pancreatic Neoplasms; Pancreatitis; Pronase; Silicone Elastomers; Vitamin B 12; Whipple Disease | 1975 |
[Clinical research and methodological study of an eupeptic-hepatotropic combination].
Topics: Adult; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Dyspepsia; Female; Homocysteine; Humans; Liver; Male; Peptide Hydrolases; Phosphorylcholine; Vitamin B 12 | 1975 |
Effects of sub-50 oral contraceptives on homocysteine metabolism: a preliminary study.
Topics: Adult; Cardiovascular Diseases; Causality; Contraceptives, Oral; Desogestrel; Fasting; Female; Homocysteine; Humans; Norpregnenes; Pyridoxal Phosphate; Vitamin B 12 | 1992 |
[Treatment of liver damage during a course of tuberculosis and chronic pulmonary diseases. Necessity of treatment and new trends].
Topics: Bilirubin; Choline; Chronic Disease; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Female; Homocysteine; Humans; Lactones; Liver; Liver Diseases; Liver Function Tests; Lung Diseases; Male; Peritonitis; Pleurisy; Silicotuberculosis; Transaminases; Tuberculosis, Pulmonary; Vitamin B 12 | 1974 |
[Controlled clinical trial of a new combination of phosphorylcholine, homocysteine-gamma-thiolactone and vitamin B 12 in the parenteral treatment of chronic hepatopathies].
Topics: Adult; Aged; Choline; Chronic Disease; Drug Combinations; Evaluation Studies as Topic; Female; Homocysteine; Humans; Lactones; Liver Diseases; Liver Function Tests; Male; Middle Aged; Phosphoric Acids; Vitamin B 12 | 1974 |
Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations.
Topics: Aged; Aged, 80 and over; Avitaminosis; Citrates; Cystathionine; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Injections, Intramuscular; Male; Methylmalonic Acid; Placebos; Prospective Studies; Pyridoxine; Vitamin B 12; Vitamin B 12 Deficiency | 1995 |
Neural tube defects and elevated homocysteine levels in amniotic fluid.
Topics: Adult; Amniotic Fluid; Female; Fetal Diseases; Folic Acid; Gestational Age; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Pregnancy Trimester, Second; Pyridoxine; Vitamin B 12 | 1995 |
Vitamin requirements for the treatment of hyperhomocysteinemia in humans.
Topics: Adult; Aged; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Placebos; Pyridoxine; Vitamin B 12 | 1994 |
Hyperhomocysteinemia and the response to vitamin supplementation.
Topics: Adolescent; Adult; Aged; Diet; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Pyridoxine; Vitamin B 12 | 1993 |
Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia.
Topics: Adult; Aged; Cardiovascular Diseases; Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Double-Blind Method; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Pyridoxine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 1993 |
Folate, vitamin B12, and homocysteine in major depressive disorder.
Topics: Adolescent; Adult; Ambulatory Care; Depressive Disorder; Female; Fluoxetine; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Unpredictable intra-individual variations in serum homocysteine levels on folic acid supplementation.
Topics: Adolescent; Adult; Aged; Female; Folic Acid; Folic Acid Deficiency; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12 | 1997 |
Folate, vitamin B12, homocysteine status and chromosome damage rate in lymphocytes of older men.
Topics: Aged; Chromosome Aberrations; DNA Damage; Folic Acid; Homocysteine; Humans; Lymphocytes; Male; Micronuclei, Chromosome-Defective; Middle Aged; Vitamin B 12 | 1997 |
Metformin increases total serum homocysteine levels in non-diabetic male patients with coronary heart disease.
Topics: Adult; Coronary Disease; Cysteine; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Methylmalonic Acid; Middle Aged; Vitamin B 12 | 1997 |
Treatment of hyperhomocysteinemia in renal transplant recipients. A randomized, placebo-controlled trial.
Topics: Drug Therapy, Combination; Factor Analysis, Statistical; Folic Acid; Homocysteine; Humans; Kidney Transplantation; Methionine; Pyridoxine; Risk Factors; Vitamin B 12 | 1997 |
677C to T mutation in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene and plasma homocyst(e)ine levels in patients with TIA or minor stroke.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Aged; Aged, 80 and over; Analysis of Variance; Cerebrovascular Disorders; Female; Folic Acid; Homocysteine; Humans; Ischemic Attack, Transient; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases; Risk Factors; Vitamin B 12 | 1998 |
Effect of B-group vitamins and antioxidant vitamins on hyperhomocysteinemia: a double-blind, randomized, factorial-design, controlled trial.
Topics: Adult; Age Factors; Analysis of Variance; Antioxidants; Ascorbic Acid; beta Carotene; Blood Pressure; Body Mass Index; Cholesterol; Diastole; Dietary Supplements; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Pyridoxine; Reference Values; Smoking; Systole; Triglycerides; Vitamin B 12; Vitamin E | 1998 |
Folate, vitamin B12, homocysteine status and DNA damage in young Australian adults.
Topics: Adult; Chromosome Aberrations; Cross-Sectional Studies; Dietary Supplements; DNA; DNA Damage; DNA Methylation; Double-Blind Method; Female; Folic Acid; Hematinics; Homocysteine; Humans; Lymphocytes; Male; Micronuclei, Chromosome-Defective; Placebos; Vitamin B 12 | 1998 |
The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
Topics: Adult; Cysteine; Diet; Double-Blind Method; Edible Grain; Erythrocytes; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Middle Aged; Placebos; Vitamin B 12 | 1998 |
Effective treatment of cobalamin deficiency with oral cobalamin.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Female; Folic Acid; Hematocrit; Homocysteine; Humans; Injections, Intramuscular; Male; Methylmalonic Acid; Middle Aged; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 1998 |
Changes in folate status as determined by reduction in total plasma homocysteine levels during leucovorin modulation of 5-fluorouracil therapy in cancer patients.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colorectal Neoplasms; Creatinine; Erythrocytes; Female; Fluorouracil; Folic Acid; Homocysteine; Humans; Leucovorin; Male; Middle Aged; Vitamin B 12 | 1998 |
Elevated homocysteine levels indicate suboptimal folate status in pediatric sickle cell patients.
Topics: Adolescent; Anemia, Sickle Cell; Child; Child, Preschool; Dietary Supplements; Female; Folic Acid; Hemoglobin SC Disease; Homocysteine; Humans; Infant; Male; Pyridoxine; Vitamin B 12 | 1998 |
Correlation between total homocysteine and cyclosporine concentrations in cardiac transplant recipients.
Topics: Adult; Aged; Cyclosporine; Female; Folic Acid; Heart Transplantation; Homocysteine; Humans; Immunosuppressive Agents; Kidney Glomerulus; Linear Models; Male; Metabolic Diseases; Methionine; Middle Aged; Postoperative Complications; Vitamin B 12 | 1998 |
Effects of folic acid and combinations of folic acid and vitamin B-12 on plasma homocysteine concentrations in healthy, young women.
Topics: Adult; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 1998 |
Folate administration reduces circulating homocysteine levels in NIDDM patients on long-term metformin treatment.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dipeptides; Double-Blind Method; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Prospective Studies; Risk Factors; Time Factors; Treatment Outcome; Vitamin B 12 | 1998 |
Reduction of homocysteine levels in coronary artery disease by low-dose folic acid combined with vitamins B6 and B12.
Topics: Coronary Disease; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Pyridoxine; Single-Blind Method; Vitamin B 12 | 1999 |
Influence of sulphasalazine, methotrexate, and the combination of both on plasma homocysteine concentrations in patients with rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Digestive System; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Sulfasalazine; Vitamin B 12 | 1999 |
Plasma total homocysteine response to oral doses of folic acid and pyridoxine hydrochloride (vitamin B6) in healthy individuals. Oral doses of vitamin B6 reduce concentrations of serum folate.
Topics: Administration, Oral; Adult; Cholesterol; Cysteine; Dipeptides; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins; Male; Middle Aged; Norway; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Vitamin B 12 | 1999 |
Hyperhomocysteinemia in high-aged subjects: relation of B-vitamins, folic acid, renal function and the methylenetetrahydrofolate reductase mutation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Regression Analysis; Risk Assessment; Risk Factors; Statistics, Nonparametric; Vitamin B 12 | 1999 |
Lowering of homocysteine concentrations in elderly men and women.
Topics: Aged; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; Pyridoxine; Vitamin B 12 | 1999 |
Serum homocysteine increases after therapy with fenofibrate or bezafibrate.
Topics: Adult; Bezafibrate; Chromatography, High Pressure Liquid; Fenofibrate; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Hypertriglyceridemia; Hypolipidemic Agents; Male; Middle Aged; Pilot Projects; Pyridoxine; Vitamin B 12 | 1999 |
Pathological changes in cobalt-supplemented and non-supplemented twin lambs in relation to blood concentrations of methylmalonic acid and homocysteine.
Topics: Animals; Brain; Brain Diseases; Cobalt; Copper; Diet; Female; Hepatitis, Chronic; Homocysteine; Litter Size; Liver; Male; Methylmalonic Acid; Sheep; Sheep Diseases; Twins; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Elevated serum levels of methylmalonic acid and homocysteine in elderly people. A population-based intervention study.
Topics: Administration, Oral; Aged; Female; Folic Acid; Hematinics; Homocysteine; Humans; Injections, Intramuscular; Male; Methylmalonic Acid; Treatment Outcome; Vitamin B 12 | 1999 |
Long-term diuretic therapy in hypertensive patients: effects on serum homocysteine, vitamin B6, vitamin B12, and red blood cell folate concentrations.
Topics: Diuretics; Female; Folic Acid; Homocysteine; Humans; Hypertension; Linear Models; Male; Middle Aged; Prospective Studies; Pyridoxine; Statistics, Nonparametric; Time Factors; Vitamin B 12 | 1999 |
Micronucleus frequency in human lymphocytes is related to plasma vitamin B12 and homocysteine.
Topics: Adolescent; Adult; Aged; Cell Division; Cross-Sectional Studies; Double-Blind Method; Environmental Monitoring; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lymphocytes; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Folic Acid; Genotype; Homocysteine; Humans; Isoenzymes; Male; Middle Aged; Polymorphism, Genetic; Pyridoxine; Vitamin B 12 | 1999 |
Increased dietary micronutrients decrease serum homocysteine concentrations in patients at high risk of cardiovascular disease.
Topics: Adult; Aged; Analysis of Variance; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diet; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperlipidemias; Hypertension; Male; Middle Aged; Pyridoxine; Risk Factors; Vitamin B 12 | 1999 |
Elevated serum levels of methylmalonic acid and homocysteine in elderly people. A population-based intervention study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Drug Therapy, Combination; Female; Folic Acid; Hematinics; Homocysteine; Humans; Injections, Intramuscular; Male; Methylmalonic Acid; Population Surveillance; Treatment Outcome; Vitamin B 12 | 1999 |
Carotid artery stiffness in patients with end-stage renal disease: no effect of long-term homocysteine-lowering therapy.
Topics: Age Factors; Analysis of Variance; Biomarkers; Blood Pressure; Brachial Artery; Carotid Artery, Common; Compliance; Endothelins; Homocysteine; Humans; Kidney Failure, Chronic; Pyridoxine; Regression Analysis; Renal Dialysis; Vasodilation; Vitamin B 12; von Willebrand Factor | 2000 |
A tale of two homocysteines--and two hemodialysis units.
Topics: Aged; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Cystine; Female; Fluorometry; Folic Acid; Hematinics; Hemodialysis Units, Hospital; Homocysteine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Regression Analysis; Vitamin B 12 | 2000 |
Low-dose folic acid supplementation does not influence plasma methionine concentrations in young non-pregnant women.
Topics: Adolescent; Adult; Contraceptives, Oral; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Vitamin B 12 | 1999 |
A high-fat diet induces and red wine counteracts endothelial dysfunction in human volunteers.
Topics: Alkaline Phosphatase; Brachial Artery; Diet; Dietary Fats; Endothelium, Vascular; Fatty Acids; Fatty Acids, Omega-3; Fruit; gamma-Glutamyltransferase; Homocysteine; Humans; Male; Nitroglycerin; Transaminases; Vasodilation; Vasodilator Agents; Vegetables; Vitamin B 12; Wine | 2000 |
The plasma homocysteine concentration is better than that of serum methylmalonic acid as a marker for sociopsychological performance in a psychogeriatric population.
Topics: Aged; Aged, 80 and over; Dementia; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Methylmalonic Acid; Psychiatric Status Rating Scales; Regression Analysis; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Dietary strategies for lowering homocysteine concentrations.
Topics: Adult; Aged; Blood Glucose; Body Weight; Diet; Dietary Supplements; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Lipoproteins; Male; Middle Aged; Vitamin B 12 | 2000 |
Correlates of total plasma homocysteine: folic acid, copper, and cervical dysplasia.
Topics: Case-Control Studies; Contraceptives, Oral; Copper; Diet; Dietary Fats; Dietary Supplements; Erythrocytes; Ethnicity; Fatty Acids, Unsaturated; Female; Folic Acid; Homocysteine; Humans; Linear Models; Risk Factors; Uterine Cervical Dysplasia; Vitamin B 12 | 2000 |
Homocysteine, folate, methylation, and monoamine metabolism in depression.
Topics: Adult; Biogenic Monoamines; Blood Cell Count; Body Weight; Depression; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Methylation; Middle Aged; S-Adenosylmethionine; Vitamin B 12 | 2000 |
The effect of 677C-->T and 1298A-->C mutations on plasma homocysteine and 5,10-methylenetetrahydrofolate reductase activity in healthy subjects.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Female; Folic Acid; Heterozygote; Homocysteine; Homozygote; Humans; Lymphocytes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases; Point Mutation; Polymorphism, Genetic; Vitamin B 12 | 2000 |
Effect of dietary patterns on serum homocysteine: results of a randomized, controlled feeding study.
Topics: Adult; Aged; Diet; Dietary Fats; Fasting; Female; Folic Acid; Fruit; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Pyridoxal Phosphate; Vegetables; Vitamin B 12 | 2000 |
Enhancement of the antidepressant action of fluoxetine by folic acid: a randomised, placebo controlled trial.
Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Sex Factors; Treatment Outcome; Vitamin B 12 | 2000 |
Effect of folic acid and antioxidant vitamins on endothelial dysfunction in patients with coronary artery disease.
Topics: Aged; Antioxidants; Ascorbic Acid; Blood Circulation; Coronary Disease; Double-Blind Method; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Malondialdehyde; Middle Aged; Nitroglycerin; Vasodilation; Vasodilator Agents; Vitamin B 12; Vitamin E | 2000 |
Homocysteine and venous thrombosis: outline of a vitamin intervention trial.
Topics: Adult; Aged; Aged, 80 and over; Comorbidity; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Netherlands; Prospective Studies; Pulmonary Embolism; Pyridoxine; Retrospective Studies; Secondary Prevention; Thrombophilia; Thrombophlebitis; Treatment Outcome; Ultrasonography; Venous Thrombosis; Vitamin B 12 | 2000 |
Fluctuations in dietary methionine intake do not alter plasma homocysteine concentration in healthy men.
Topics: Adult; Body Mass Index; Diet; Diet Records; Energy Intake; Homocysteine; Humans; Male; Methionine; Vitamin B 12 | 2000 |
Improved vascular endothelial function after oral B vitamins: An effect mediated through reduced concentrations of free plasma homocysteine.
Topics: Adult; Aged; Blood Glucose; Brachial Artery; Cholesterol; Cholesterol, HDL; Coronary Disease; Dietary Supplements; Double-Blind Method; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Nitroglycerin; Regression Analysis; Triglycerides; Ultrasonography; Vasodilator Agents; Vitamin B 12 | 2000 |
A pilot study with simvastatin and folic acid/vitamin B12 in preparation for the Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH).
Topics: Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Factor Analysis, Statistical; Female; Folic Acid; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Pilot Projects; Placebos; Simvastatin; Triglycerides; Vitamin B 12 | 2000 |
Influence of methylenetetrahydrofolate reductase genotype, age, vitamin B-12, and folate status on plasma homocysteine in children.
Topics: Adolescent; Aging; Chi-Square Distribution; Child; Child, Preschool; Chromatography, High Pressure Liquid; Fasting; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymerase Chain Reaction; Radioimmunoassay; Vitamin B 12 | 2000 |
Multivitamin/mineral supplementation improves plasma B-vitamin status and homocysteine concentration in healthy older adults consuming a folate-fortified diet.
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Cerebrovascular Disorders; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Middle Aged; Minerals; Nutritional Status; Pyridoxal Phosphate; Risk Factors; Vitamin B 12; Vitamin B Complex; Vitamins | 2000 |
Plasma homocysteine concentrations in the acute and convalescent periods of atherothrombotic stroke.
Topics: Acute Disease; Adult; Aged; Arteriosclerosis; Brain; Case-Control Studies; Chromatography, High Pressure Liquid; Convalescence; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Lipids; Male; Middle Aged; Regression Analysis; Risk Factors; Scotland; Stroke; Stroke Rehabilitation; Tomography, X-Ray Computed; Vitamin B 12 | 2001 |
Vitamin Intervention for Stroke Prevention (VISP) trial: rationale and design.
Topics: Adult; Aged; Cerebral Infarction; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Homocysteine; Homocystine; Humans; Male; Middle Aged; Pyridoxine; Risk Factors; Vitamin B 12 | 2001 |
Homocysteine, fibrinogen, and lipoprotein(a) levels are simultaneously reduced in patients with chronic renal failure treated with folic acid, pyridoxine, and cyanocobalamin.
Topics: Adult; Arteriosclerosis; Cholesterol; Creatinine; Drug Therapy, Combination; Female; Fibrinogen; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Lipoprotein(a); Male; Pyridoxine; Renal Dialysis; Risk Factors; Triglycerides; Urea; Uric Acid; Vitamin B 12; Vitamin B Complex | 2001 |
Oral vitamin B(12) and high-dose folic acid in hemodialysis patients with hyper-homocyst(e)inemia.
Topics: Administration, Oral; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Dialysis; Vitamin B 12 | 2001 |
Consumption of high doses of chlorogenic acid, present in coffee, or of black tea increases plasma total homocysteine concentrations in humans.
Topics: Adult; Cardiovascular Diseases; Chlorogenic Acid; Coffee; Cross-Over Studies; Fasting; Female; Flavonoids; Folic Acid; Glucosides; Homocysteine; Humans; Male; Phenols; Polymers; Postprandial Period; Pyridoxine; Quercetin; Risk Factors; Tea; Vitamin B 12 | 2001 |
Parenteral vitamin B12 reduces hyperhomocysteinemia in end-stage renal disease.
Topics: Cysteine; Homocysteine; Humans; Hyperhomocysteinemia; Injections, Subcutaneous; Kidney Failure, Chronic; Methylmalonic Acid; Renal Dialysis; Vitamin B 12 | 2001 |
Efficacy of folinic versus folic acid for the correction of hyperhomocysteinemia in hemodialysis patients.
Topics: Double-Blind Method; Drug Administration Schedule; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infusions, Intravenous; Leucovorin; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Renal Dialysis; Treatment Outcome; Vitamin B 12 | 2001 |
Association of the B-vitamins pyridoxal 5'-phosphate (B(6)), B(12), and folate with lung cancer risk in older men.
Topics: Age Distribution; Aged; Case-Control Studies; Cohort Studies; Confidence Intervals; Finland; Folic Acid; Homocysteine; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Odds Ratio; Pyridoxine; Reference Values; Risk Factors; Sampling Studies; Sensitivity and Specificity; Vitamin B 12 | 2001 |
High-dose simvastin (80 mg/day) decreases plasma concentrations of total homocyst(e)ine in patients with hypercholesteromia.
Topics: Cholesterol; Folic Acid; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Prospective Studies; Simvastatin; Vitamin B 12 | 2001 |
Homocysteine lowering effect of different multivitamin preparations in patients with end-stage renal disease.
Topics: Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Pyridoxine; Renal Dialysis; Vitamin B 12 | 2001 |
Effects of growth hormone (GH) administration on homocyst(e)ine levels in men with GH deficiency: a randomized controlled trial.
Topics: Adult; Folic Acid; Growth Hormone; Homocysteine; Homocystine; Humans; Male; Middle Aged; Nutrition Assessment; Single-Blind Method; Thyroid Hormones; Time Factors; Vitamin B 12 | 2001 |
Improvement of cognitive functions after cobalamin/folate supplementation in elderly patients with dementia and elevated plasma homocysteine.
Topics: Aged; Attention; Biomarkers; Cognition Disorders; Dementia; Female; Folic Acid; Homocysteine; Humans; Male; Memory; Mental Status Schedule; Vitamin B 12 | 2001 |
Homocyst(e)ine metabolism in hemodialysis patients treated with vitamins B6, B12 and folate.
Topics: Female; Folic Acid; Hematinics; Homocysteine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pyridoxine; Regression Analysis; Renal Dialysis; Vitamin B 12; Vitamin B Complex | 2001 |
Vitamin B12 treatment normalizes metabolic markers but has limited clinical effect: a randomized placebo-controlled study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Neurologic Examination; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Homocysteine levels in patients treated with lipid apheresis: effect of a vitamin therapy.
Topics: Adult; Cystathionine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipoproteinemia Type II; Lipids; Male; Vitamin B 12; Vitamin B 6 | 2001 |
Oral cobalamin therapy for the treatment of patients with food-cobalamin malabsorption.
Topics: Administration, Oral; Aged; Aged, 80 and over; Blood Cell Count; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nutrition Disorders; Prospective Studies; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Vitamin supplementation can markedly reduce the homocysteine elevation induced by fenofibrate.
Topics: Cross-Over Studies; Double-Blind Method; Fenofibrate; Folic Acid; Homocysteine; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Pyridoxine; Vitamin B 12; Vitamins | 2001 |
Determinants of cobalamin status in newborns.
Topics: Adult; Biomarkers; Female; Homocysteine; Humans; Infant, Newborn; Logistic Models; Maternal-Fetal Exchange; Methylmalonic Acid; Parity; Pregnancy; Reference Values; Vitamin B 12 | 2001 |
Folate supplementation in peritoneal dialysis patients with normal erythrocyte folate: effect on plasma homocysteine.
Topics: Anorexia; Depression; Down-Regulation; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Kidney Diseases; Male; Middle Aged; Peritoneal Dialysis; Sleep Initiation and Maintenance Disorders; Vitamin B 12 | 2001 |
Plasma homocysteine concentration in children with chronic renal failure.
Topics: Adolescent; Aging; Child; Child, Preschool; Diet; Female; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Infant; Kidney Failure, Chronic; Kidney Function Tests; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Reference Values; Renal Dialysis; Vitamin B 12 | 2001 |
Preoperative oral B vitamins prevent nitrous oxide-induced postoperative plasma homocysteine increases.
Topics: Administration, Oral; Aged; Anesthetics, Inhalation; Arthroplasty, Replacement; Double-Blind Method; Female; Homocysteine; Humans; Male; Nitrous Oxide; Preoperative Care; Prospective Studies; Reoperation; Single-Blind Method; Vitamin B 12; Vitamin B 6 | 2001 |
Decreased rate of coronary restenosis after lowering of plasma homocysteine levels.
Topics: Angioplasty, Balloon, Coronary; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Pyridoxine; Vitamin B 12 | 2001 |
[Effect of hypolipemic agents on levels of total plasma homocysteine].
Topics: Adolescent; Adult; Aged; Cholesterol; Female; Folic Acid; Homocysteine; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Male; Middle Aged; Pravastatin; Vitamin B 12; Vitamin B 6 | 2001 |
Importance of both folic acid and vitamin B12 in reduction of risk of vascular disease.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2002 |
[A case-control study on the relationship between abnormal homocysteine metabolism and essential hypertension].
Topics: Adult; Aged; Case-Control Studies; China; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymorphism, Restriction Fragment Length; Risk Factors; Vitamin B 12 | 2000 |
Efficacy of methylcobalamin on lowering total homocysteine plasma concentrations in haemodialysis patients receiving high-dose folic acid supplementation.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Osmolar Concentration; Renal Dialysis; Vitamin B 12; Vitamin B 6 | 2002 |
Randomized trial of methylcobalamin and folate effects on homocysteine in hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Prospective Studies; Renal Dialysis; Vitamin B 12 | 2002 |
A randomized, double-blind, placebo-controlled study of oral vitamin B12 supplementation in older patients with subnormal or borderline serum vitamin B12 concentrations.
Topics: Administration, Oral; Aged; Aged, 80 and over; Dietary Supplements; Double-Blind Method; Female; Food, Fortified; Health Services for the Aged; Homocysteine; Hospitals, Special; Humans; Male; Victoria; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Hydroxocobalamin reduces hyperhomocysteinemia in end-stage renal disease.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Hyperhomocysteinemia; Injections, Subcutaneous; Kidney Failure, Chronic; Male; Methylmalonic Acid; Middle Aged; Prospective Studies; Renal Dialysis; Treatment Outcome; Vitamin B 12 | 2002 |
Assessment of three levels of folic acid on serum folate and plasma homocysteine: a randomised placebo-controlled double-blind dietary intervention trial.
Topics: Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Double-Blind Method; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neural Tube Defects; Nutritional Requirements; Placebos; Vitamin B 12 | 2002 |
Effect of supplementation with folic-acid on relation between plasma homocysteine, folate, and vitamin B12.
Topics: Diet; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Vitamin B 12 | 2002 |
Effect of homocysteine-lowering therapy with folic acid, vitamin B12, and vitamin B6 on clinical outcome after percutaneous coronary intervention: the Swiss Heart study: a randomized controlled trial.
Topics: Angioplasty, Balloon, Coronary; Coronary Angiography; Coronary Stenosis; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Prospective Studies; Vitamin B 12; Vitamin B 6 | 2002 |
Effects of folic acid and vitamin B12 supplements on folate and homocysteine metabolism in pigs during early pregnancy.
Topics: Animal Nutritional Physiological Phenomena; Animals; Dietary Supplements; Female; Folic Acid; Homocysteine; Parity; Pregnancy; Pregnancy, Animal; Swine; Uterus; Vitamin B 12 | 2002 |
Effect of riboflavin supplementation on plasma homocysteine in elderly people with low riboflavin status.
Topics: Aged; Analysis of Variance; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; Northern Ireland; Photosensitizing Agents; Riboflavin; Riboflavin Deficiency; Vitamin B 12 | 2002 |
Effects of folate treatment and homocysteine lowering on resistance vessel reactivity in atherosclerotic subjects.
Topics: Arteriosclerosis; Blood Flow Velocity; Cholesterol; Coronary Disease; Cross-Over Studies; Folic Acid; Forearm; Homocysteine; Humans; Male; Middle Aged; Placebos; Regional Blood Flow; Triglycerides; Vascular Resistance; Vitamin B 12 | 2002 |
The effect of B-vitamins on hyperhomocysteinemia in patients on antiepileptic drugs.
Topics: Adult; Anticonvulsants; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Epilepsy; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intercellular Adhesion Molecule-1; Male; Malondialdehyde; Methionine; Middle Aged; Pyridoxic Acid; Riboflavin; Selectins; Vascular Cell Adhesion Molecule-1; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2002 |
Homocysteine, cysteine, and B vitamins as predictors of kidney disease progression.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Biomarkers; Blood Pressure Monitoring, Ambulatory; Cysteine; Diet, Protein-Restricted; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Kidney Diseases; Male; Middle Aged; Prognosis; Pyridoxal Phosphate; Risk Factors; Vitamin B 12 | 2002 |
Response of elevated methylmalonic acid to three dose levels of oral cobalamin in older adults.
Topics: Administration, Oral; Age Factors; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Pilot Projects; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Vitamin intervention for stroke prevention.
Topics: Aged; Diet; Double-Blind Method; Electrocardiography; Endpoint Determination; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Recurrence; Risk Factors; Stroke; Vitamin B 12; Vitamin B 6; Vitamins | 2002 |
Hyperhomocysteinemia and endothelial function in young subjects: effects of vitamin supplementation.
Topics: Adolescent; Adult; Dietary Supplements; Double-Blind Method; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12; Vitamin B 6 | 2002 |
Effect of protein and methionine intakes on plasma homocysteine concentrations: a 6-mo randomized controlled trial in overweight subjects.
Topics: Adolescent; Adult; Analysis of Variance; Body Weight; Diet; Diet, Protein-Restricted; Dietary Proteins; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Obesity; Vitamin B 12 | 2002 |
Contribution of caffeine to the homocysteine-raising effect of coffee: a randomized controlled trial in humans.
Topics: Adult; Aged; Caffeine; Coffee; Cross-Over Studies; Fasting; Female; Homocysteine; Humans; Male; Middle Aged; Placebos; Sex Characteristics; Vitamin B 12; Vitamin B 6 | 2002 |
Folic acid enhances endothelial function and reduces blood pressure in smokers: a randomized controlled trial.
Topics: Adult; Blood Flow Velocity; Blood Pressure; Double-Blind Method; Endothelium, Vascular; Female; Folic Acid; Forearm; Hematinics; Homocysteine; Humans; Male; Middle Aged; Regression Analysis; Smoking; Vascular Resistance; Vitamin B 12 | 2002 |
Capecitabine treatment results in increased mean corpuscular volume of red blood cells in patients with advanced solid malignancies.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Erythrocyte Indices; Erythrocytes; Female; Fluorouracil; Folic Acid; Hematinics; Homocysteine; Humans; Male; Middle Aged; Neoplasms; Prospective Studies; Retrospective Studies; Thymidylate Synthase; Vitamin B 12 | 2003 |
Vitamin B12 decreases, but does not normalize, homocysteine and methylmalonic acid in end-stage renal disease: a link with glycine metabolism and possible explanation of hyperhomocysteinemia in end-stage renal disease.
Topics: Cysteine; Genotype; Glycine; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Threonine; Vitamin B 12 | 2003 |
Antihypertensive treatment and homocysteine concentrations.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Cardiovascular Diseases; Creatinine; Cystatin C; Cystatins; Female; Folic Acid; Homocysteine; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6 | 2003 |
The effect of vitamin B12 on total plasma homocysteine concentration in folate-replete hemodialysis patients.
Topics: Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Middle Aged; Renal Dialysis; Statistics, Nonparametric; Treatment Outcome; Vitamin B 12 | 2003 |
Can black tea influence plasma total homocysteine concentrations?
Topics: Adult; Aged; Blood Pressure; Body Mass Index; Cholesterol; Cross-Over Studies; Female; Flavonoids; Folic Acid; Gallic Acid; Homocysteine; Humans; Lipids; Male; Methylation; Middle Aged; Phenols; Polymers; Polyphenols; Tea; Vitamin B 12; Vitamin B 6 | 2003 |
Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status.
Topics: Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Linear Models; Male; Middle Aged; Parkinson Disease; Pyridoxal Phosphate; Risk Factors; Vitamin B 12; Vitamin B Complex | 2003 |
Plasma homocysteine concentration is decreased by dietary intervention.
Topics: Adult; Cross-Over Studies; Diet; Erythrocytes; Female; Folic Acid; Fruit; Homocysteine; Humans; Middle Aged; Vegetables; Vitamin B 12 | 2003 |
Effect of homocysteine-lowering therapy on restenosis after percutaneous coronary intervention for narrowings in small coronary arteries.
Topics: Angioplasty, Balloon, Coronary; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Prospective Studies; Stents; Vitamin B 12; Vitamin B 6 | 2003 |
Efficacy of short-term oral cobalamin therapy for the treatment of cobalamin deficiencies related to food-cobalamin malabsorption: a study of 30 patients.
Topics: Aged; Aged, 80 and over; Blood Cell Count; Female; Hemoglobins; Homocysteine; Humans; Malabsorption Syndromes; Male; Middle Aged; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Effect of vitamins and aspirin on markers of platelet activation, oxidative stress and homocysteine in people at high risk of dementia.
Topics: Aged; Aged, 80 and over; Aspirin; Cognition Disorders; Dementia; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Isoprostanes; Male; Middle Aged; Oxidative Stress; Platelet Activation; Platelet Aggregation Inhibitors; Riboflavin; Thromboxanes; Vitamin B 12; Vitamins | 2003 |
Plasma homocysteine and S-adenosylmethionine in erythrocytes as determinants of carotid intima-media thickness: different effects in diabetic and non-diabetic individuals. The Hoorn Study.
Topics: Aged; Arteriosclerosis; Carotid Arteries; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Erythrocytes; Female; Homocysteine; Humans; Male; Middle Aged; S-Adenosylmethionine; Tunica Intima; Tunica Media; Vitamin B 12; Vitamin B 6 | 2003 |
Influence of anticalcineurinic therapy in plasma homocysteine levels of renal transplant recipients: a prospective study.
Topics: Adult; Calcineurin Inhibitors; Creatinine; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Kidney Transplantation; Male; Middle Aged; Regression Analysis; Time Factors; Vitamin B 12 | 2003 |
Treatment of hyperhomocysteinemia after renal transplantation.
Topics: Adult; Aged; Creatinine; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Reproducibility of Results; Safety; Time Factors; Vitamin B 12 | 2003 |
Homocysteine and its relation to B-vitamins in Graves' disease before and after treatment: effect modification by smoking.
Topics: Adolescent; Adult; Aged; Antithyroid Agents; Carbimazole; Creatinine; Female; Folic Acid; Graves Disease; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Regression Analysis; Riboflavin; Smoking; Vitamin B 12; Vitamin B Complex | 2003 |
Plasma total homocysteine in Mexican rural and urban women fed typical model diets.
Topics: Adolescent; Adult; Cross-Over Studies; Diet; Fasting; Female; Folic Acid; Homocysteine; Humans; Methionine; Mexico; Middle Aged; Nutritional Status; Reference Values; Rural Health; Urban Health; Vitamin B 12 | 2003 |
Neuropsychiatric disturbances in presumed late-onset cobalamin C disease.
Topics: Adolescent; Adult; Brain; Cobamides; Female; Fibroblasts; Homocysteine; Humans; Mental Disorders; Metabolism, Inborn Errors; Methylmalonic Acid; Nervous System Diseases; Sural Nerve; Vitamin B 12 | 2003 |
Reduction of plasma homocysteine and serum methylmalonate concentrations in apparently healthy elderly subjects after treatment with folic acid, vitamin B12 and vitamin B6: a randomised trial.
Topics: Aged; Aged, 80 and over; Double-Blind Method; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Methylmalonic Acid; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2003 |
Background and rationale of the SU.FOL.OM3 study: double-blind randomized placebo-controlled secondary prevention trial to test the impact of supplementation with folate, vitamin B6 and B12 and/or omega-3 fatty acids on the prevention of recurrent ischemi
Topics: Aged; Aged, 80 and over; Coronary Artery Disease; Dietary Supplements; Double-Blind Method; Fatty Acids, Omega-3; Female; Folic Acid; Homocysteine; Humans; Intracranial Arteriosclerosis; Ischemia; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk Factors; Secondary Prevention; Vitamin B 12; Vitamin B 6 | 2003 |
Measurement of carotid plaque and effect of vitamin therapy for total homocysteine.
Topics: Aged; Carotid Stenosis; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Humans; Imaging, Three-Dimensional; Reproducibility of Results; Stroke; Ultrasonography; Vitamin B 12; Vitamin B 6; Vitamins | 2003 |
Randomized, placebo-controlled trial of intramuscular vitamin B12 for the treatment of hyperhomocysteinaemia in dialysis patients.
Topics: Adult; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Injections, Intramuscular; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Renal Dialysis; Vitamin B 12 | 2003 |
Betaine as a determinant of postmethionine load total plasma homocysteine before and after B-vitamin supplementation.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Betaine; Choline; Coronary Angiography; Dietary Supplements; Drug Administration Schedule; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Methionine; Methyltransferases; Middle Aged; Sarcosine; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2004 |
Lipid, glucose and homocysteine metabolism in women treated with a GnRH agonist with or without raloxifene.
Topics: Adult; Blood Glucose; Body Constitution; Body Mass Index; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Delayed-Action Preparations; Female; Folic Acid; Homeostasis; Homocysteine; Humans; Insulin; Insulin Resistance; Leiomyoma; Leuprolide; Lipids; Middle Aged; Placebos; Premenopause; Raloxifene Hydrochloride; Triglycerides; Uterine Neoplasms; Vitamin B 12 | 2004 |
Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial.
Topics: Adult; Aged; Coronary Disease; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Myocardial Infarction; Recurrence; Risk; Stroke; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2004 |
Plant sterol-fortified orange juice effectively lowers cholesterol levels in mildly hypercholesterolemic healthy individuals.
Topics: Adult; Aged; Apolipoproteins B; Beverages; Cholesterol; Cholesterol, LDL; Citrus; Double-Blind Method; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hypercholesterolemia; Male; Middle Aged; Phytosterols; Sitosterols; Stigmasterol; Treatment Outcome; Vitamin B 12 | 2004 |
Folic acid and vitamin B12 are more effective than vitamin B6 in lowering fasting plasma homocysteine concentration in patients with coronary artery disease.
Topics: Adult; Aged; Aged, 80 and over; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Male; Mental Recall; Middle Aged; Single-Blind Method; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2004 |
The short-term bioavailabilities of [6S]-5-methyltetrahydrofolate and folic acid are equivalent in men.
Topics: Adult; Biological Availability; Cross-Over Studies; Diet; Double-Blind Method; Energy Intake; Folic Acid; Genotype; Homocysteine; Humans; Kinetics; Male; Methylenetetrahydrofolate Reductase (NADPH2); Tetrahydrofolates; Time Factors; Vitamin B 12 | 2004 |
Blood levels of homocysteine, folate, vitamin B6 and B12 in women using oral contraceptives compared to non-users.
Topics: Adult; Contraceptives, Oral; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Risk Assessment; Thromboembolism; Vitamin B 12; Vitamin B 6 | 2003 |
Effects of folic acid fortification and multivitamin therapy on homocysteine and vitamin B(12) status in cardiac transplant recipients.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Canada; Cohort Studies; Dietary Supplements; Female; Ferredoxin-NADP Reductase; Folic Acid; Food, Fortified; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamins | 2004 |
Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial.
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Double-Blind Method; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methionine; Middle Aged; Vitamin B 12; Vitamin B 6 | 2004 |
Comparative study of response to treatment with supraphysiologic doses of B-vitamins in hyperhomocysteinemic hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Prospective Studies; Renal Dialysis; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2004 |
Effects of moderate alcohol consumption on folate and vitamin B(12) status in postmenopausal women.
Topics: Aged; Alcohol Drinking; Cross-Over Studies; DNA Methylation; Dose-Response Relationship, Drug; Ethanol; Female; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Nutritional Status; Postmenopause; Vitamin B 12 | 2004 |
[Study of the effect of medicinal product "STRESSEN" on blood levels of homocysteine in patients with current cardiovascular disease].
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Drug Combinations; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Vitamin B 12 | 2004 |
[Comparison of treatment with STRESSEN and arginine glutamate on homocysteine blood levels].
Topics: Dipeptides; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Single-Blind Method; Vitamin B 12 | 2004 |
Folate therapy and in-stent restenosis after coronary stenting.
Topics: Aged; Coronary Angiography; Coronary Disease; Coronary Restenosis; Coronary Vessels; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Stents; Treatment Failure; Vitamin B 12; Vitamin B 6 | 2004 |
Cobalamin reduces homocysteine in older adults on folic acid-fortified diet: a pilot, double-blind, randomized, placebo-controlled trial.
Topics: Aged; Cognition; Double-Blind Method; Female; Food, Fortified; Homocysteine; Humans; Male; Pilot Projects; Vitamin B 12 | 2004 |
Absence of macrocytic anaemia in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anemia, Macrocytic; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Male; Platelet Count; Sex Factors; Vitamin B 12 | 2004 |
Effect of multivitamin supplementation on the homocysteine and methylmalonic acid blood concentrations in women over the age of 60 years.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Geriatric Assessment; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Minerals; Risk Assessment; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamins | 2005 |
Changes in basal and postmethionine load concentrations of total homocysteine and cystathionine after B vitamin intervention.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analysis of Variance; Cardiovascular Diseases; Cystathionine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Norway; Prospective Studies; Vitamin B 12; Vitamin B 6 | 2004 |
Serum folate, vitamin B12, and homocysteine in major depressive disorder, Part 1: predictors of clinical response in fluoxetine-resistant depression.
Topics: Adult; Ambulatory Care; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine; Folic Acid; Homocysteine; Humans; Lithium; Male; Probability; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Vitamin B 12 | 2004 |
Serum folate, vitamin B12, and homocysteine in major depressive disorder, Part 2: predictors of relapse during the continuation phase of pharmacotherapy.
Topics: Adult; Ambulatory Care; Depressive Disorder; Drug Administration Schedule; Female; Fluoxetine; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Probability; Psychiatric Status Rating Scales; Recurrence; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Vitamin B 12 | 2004 |
Effects of multivitamins and low-dose folic acid supplements on flow-mediated vasodilation and plasma homocysteine levels in older adults.
Topics: Aged; Aged, 80 and over; Brachial Artery; Dietary Supplements; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prospective Studies; Single-Blind Method; Vasodilation; Vitamin B 12; Vitamin B 6; Vitamins | 2004 |
Effects of levodopa and COMT inhibitors on plasma homocysteine in Parkinson's disease patients.
Topics: Aged; Antiparkinson Agents; Case-Control Studies; Catechols; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Levodopa; Linear Models; Male; Middle Aged; Nitriles; Parkinson Disease; Vitamin B 12 | 2005 |
Hormone replacement influences homocysteine levels in the methionine-loading test: a randomized placebo controlled trial in postmenopausal women.
Topics: Analysis of Variance; Blood Chemical Analysis; Double-Blind Method; Dydrogesterone; Estradiol; Estrogen Replacement Therapy; Female; Folic Acid; Homocysteine; Humans; Methionine; Middle Aged; Postmenopause; Pyridoxine; Treatment Outcome; Vitamin B 12 | 2004 |
The effect of folic acid and folinic acid supplements on purine metabolism in methotrexate-treated rheumatoid arthritis.
Topics: Adenosine; Aminoimidazole Carboxamide; Arthritis, Rheumatoid; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Purines; Pyridoxine; Ribonucleotides; Treatment Outcome; Vitamin B 12 | 2004 |
Insulin resistance and endothelial function are improved after folate and vitamin B12 therapy in patients with metabolic syndrome: relationship between homocysteine levels and hyperinsulinemia.
Topics: Aged; Drug Therapy, Combination; Endothelium, Vascular; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperinsulinism; Male; Metabolic Syndrome; Risk Factors; Vitamin B 12 | 2004 |
Creatine supplementation does not decrease total plasma homocysteine in chronic hemodialysis patients.
Topics: Aged; Aged, 80 and over; Creatine; Cross-Over Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Nutrition Assessment; Renal Dialysis; Vitamin B 12; Vitamin B 6 | 2004 |
Homocysteine-lowering treatment with folic acid, cobalamin, and pyridoxine does not reduce blood markers of inflammation, endothelial dysfunction, or hypercoagulability in patients with previous transient ischemic attack or stroke: a randomized substudy o
Topics: Biomarkers; Blood Coagulation; Cardiovascular Diseases; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Inflammation; Ischemic Attack, Transient; Pyridoxine; Risk Factors; Stroke; Vitamin B 12; Vitamin B Complex | 2005 |
Sustained homocysteine-lowering effect over time of folic acid-based multivitamin therapy in stroke patients despite increasing folate status in the population.
Topics: Aged; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Hematinics; Homocysteine; Humans; Male; Middle Aged; Pyridoxine; Stroke; Time Factors; Vitamin B 12 | 2005 |
Homocysteine levels in women with polycystic ovary syndrome treated with metformin versus rosiglitazone: a randomized study.
Topics: Adult; Anovulation; Blood Glucose; Body Weight; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Insulin Resistance; Lipids; Luteinizing Hormone; Metformin; Polycystic Ovary Syndrome; Rosiglitazone; Testosterone; Thiazolidinediones; Vitamin B 12 | 2005 |
[Blood concentration of homocysteine, vitamin B (12), and folic acid in patients with exudative age related macular degeneration].
Topics: Aged; Erythrocytes; Folic Acid; Homocysteine; Humans; Macular Degeneration; Vitamin B 12 | 2004 |
Effect of antihypertensive treatment with candesartan or amlodipine on glutathione and its redox status, homocysteine and vitamin concentrations in patients with essential hypertension.
Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Folic Acid; Glutathione; Glutathione Disulfide; Homocysteine; Humans; Hypertension; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Tetrazoles; Vitamin B 12 | 2005 |
S-adenosylmethionine and 5-methyltetrahydrofolate are associated with endothelial function after controlling for confounding by homocysteine: the Hoorn Study.
Topics: Aged; Brachial Artery; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nitroglycerin; Regional Blood Flow; Risk Factors; S-Adenosylmethionine; Tetrahydrofolates; Ultrasonography; Vasodilation; Vasodilator Agents; Vitamin B 12; Vitamin B 6 | 2005 |
Holotranscobalamin--a first choice assay for diagnosing early vitamin B deficiency?
Topics: Adult; Aged; Aged, 80 and over; Anemia; Biomarkers; Creatinine; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Prognosis; Thyrotropin; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Plasma homocysteine levels in Parkinson's disease: role of antiparkinsonian medications.
Topics: Aged; Antiparkinson Agents; Catechol O-Methyltransferase Inhibitors; Dopamine Agonists; Enzyme Inhibitors; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Vitamin B 12 | 2005 |
Effect of folate and mecobalamin on hip fractures in patients with stroke: a randomized controlled trial.
Topics: Aged; Bone Density; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Hemiplegia; Hip Fractures; Homocysteine; Humans; Male; Risk Factors; Stroke; Vitamin B 12 | 2005 |
Anti-heparan sulphate antibodies and homocysteine in dementia: markers of vascular pathology?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies; Biomarkers; Dementia, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Heparitin Sulfate; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2005 |
Intranasal 17beta-estradiol treatment and Vitamin B12, folate and homocysteine in menopause.
Topics: Administration, Intranasal; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Estradiol; Estrogen Replacement Therapy; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Postmenopause; Prospective Studies; Treatment Outcome; Triglycerides; Vitamin B 12 | 2005 |
Effect of L-methionine supplementation on plasma homocysteine and other free amino acids: a placebo-controlled double-blind cross-over study.
Topics: Adult; Aged; Amino Acids; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Methionine; Middle Aged; Urinary Tract Infections; Vitamin B 12; Vitamin B 6 | 2005 |
The relationship between serum folate, vitamin B12, and homocysteine levels in major depressive disorder and the timing of improvement with fluoxetine.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Female; Fluoxetine; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Vitamin B 12 | 2005 |
Oral cyanocobalamin supplementation in older people with vitamin B12 deficiency: a dose-finding trial.
Topics: Administration, Oral; Aged; Aged, 80 and over; Biomarkers; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Homocysteine; Humans; Male; Methylmalonic Acid; Radioimmunoassay; Retrospective Studies; Transcobalamins; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Cobalamin dose regimen for maximum homocysteine reduction in end-stage renal disease.
Topics: Aged; Drug Administration Schedule; Homocysteine; Humans; Injections, Intravenous; Kidney Failure, Chronic; Middle Aged; Vitamin B 12 | 2005 |
Decrease of carotid intima-media thickness in patients at risk to cerebral ischemia after supplementation with folic acid, Vitamins B6 and B12.
Topics: Aged; Brain Ischemia; Carotid Arteries; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Intracranial Arteriosclerosis; Male; Middle Aged; Risk Factors; Tunica Intima; Tunica Media; Ultrasonography; Vitamin B 12; Vitamin B 6 | 2005 |
Plasma homocysteine and markers for oxidative stress and inflammation in patients with coronary artery disease--a prospective randomized study of vitamin supplementation.
Topics: Aged; Biomarkers; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Lipid Peroxidation; Male; Middle Aged; Oxidative Stress; Pyridoxine; Vitamin B 12; Vitamins | 2005 |
[Efficacy and safety of two vitamin supplement regimens on homocysteine levels in hemodialysis patients. Prospective, randomized clinical trial].
Topics: Aged; Aged, 80 and over; Cohort Studies; Diabetic Nephropathies; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Prospective Studies; Renal Dialysis; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2005 |
Comparative effects of hydroxocobalamin and cyanocobalamin on plasma homocysteine concentrations in end-stage renal disease.
Topics: Cross-Over Studies; Female; Homocysteine; Humans; Hydroxocobalamin; Kidney Failure, Chronic; Male; Vitamin B 12 | 2005 |
Hyperhomocysteinemia in children treated with antiepileptic drugs is normalized by folic acid supplementation.
Topics: Anticonvulsants; Child; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Treatment Outcome; Vitamin B 12 | 2005 |
Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease.
Topics: Aged; Analysis of Variance; Cognition; Double-Blind Method; Drug Synergism; Female; Fibrinogen; Folic Acid; Homocysteine; Humans; Male; Riboflavin; Treatment Outcome; Vascular Diseases; Vitamin B 12; Vitamin B 6; Vitamin B Complex; von Willebrand Factor | 2005 |
Efficacy of B vitamins in lowering homocysteine in older men: maximal effects for those with B12 deficiency and hyperhomocysteinemia.
Topics: Aged; Dietary Supplements; Double-Blind Method; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Placebos; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2006 |
Low essential fatty acid and B-vitamin status in a subgroup of patients with schizophrenia and its response to dietary supplementation.
Topics: Adolescent; Adult; Cross-Sectional Studies; Dietary Supplements; Erythrocytes; Fatty Acids; Fatty Acids, Essential; Female; Fish Oils; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Schizophrenia; Sex Factors; Soybean Oil; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2006 |
Preliminary results of the effect of treatment of hyperhomocysteinemia and its relationship with inflammation, coagulation status, and endothelial function after renal transplantation.
Topics: Adult; Aged; Biomarkers; Blood Coagulation; Blood Coagulation Disorders; Brachial Artery; Creatinine; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Prospective Studies; Vitamin B 12 | 2005 |
Determining factors of the response to hyperhomocysteinemia treatment in renal transplant patients.
Topics: Adult; Aged; Analysis of Variance; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; ROC Curve; Treatment Outcome; Vitamin B 12 | 2005 |
The effect of postmenopausal hormone therapy with or without folic acid supplementation on serum homocysteine level.
Topics: Administration, Oral; Analysis of Variance; Contraceptive Agents, Female; Drug Therapy, Combination; Estradiol; Estrogen Replacement Therapy; Estrogens; Estrogens, Conjugated (USP); Female; Fluorescence Polarization; Folic Acid; Hematinics; Homocysteine; Humans; Medroxyprogesterone Acetate; Middle Aged; Postmenopause; Vitamin B 12 | 2005 |
Effects of folic acid before and after vitamin B12 on plasma homocysteine concentrations in hemodialysis patients with known MTHFR genotypes.
Topics: Aged; Female; Folic Acid; Genotype; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Renal Dialysis; Vitamin B 12; Vitamin B Complex | 2006 |
Methylenetetrahydrofolate reductase polymorphisms and homocysteine-lowering effect of vitamin therapy in Singaporean stroke patients.
Topics: Aged; Coronary Artery Disease; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Attack, Transient; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Middle Aged; Models, Statistical; Placebos; Polymorphism, Genetic; Regression Analysis; Risk Factors; Singapore; Stroke; Vitamin B 12; Vitamin B 6; Vitamins | 2006 |
Homocysteine-reducing strategies improve symptoms in chronic schizophrenic patients with hyperhomocysteinemia.
Topics: Adult; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Pyridoxine; Schizophrenia; Schizophrenic Psychology; Time Factors; Vitamin B 12; Vitamin B Complex | 2006 |
Rationale, design and baseline characteristics of a large, simple, randomized trial of combined folic acid and vitamins B6 and B12 in high-risk patients: the Heart Outcomes Prevention Evaluation (HOPE)-2 trial.
Topics: Aged; Cardiovascular Diseases; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Follow-Up Studies; Global Health; Homocysteine; Humans; Incidence; Male; Middle Aged; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2006 |
Association of folate with hearing is dependent on the 5,10-methylenetetrahdyrofolate reductase 677C-->T mutation.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Aged; Auditory Threshold; Female; Folic Acid; Genetic Predisposition to Disease; Hearing Loss, Sensorineural; Homocysteine; Humans; Incidence; Male; Middle Aged; Mutation; Netherlands; Polymorphism, Genetic; Risk Assessment; Risk Factors; Severity of Illness Index; Vitamin B 12 | 2006 |
Effects of two different oral contraceptives on homocysteine metabolism in women with polycystic ovary syndrome.
Topics: Adult; Blood Glucose; Contraceptives, Oral; Cyproterone Acetate; Desogestrel; Ethinyl Estradiol; Female; Folic Acid; Homocysteine; Humans; Insulin; Insulin Resistance; Polycystic Ovary Syndrome; Vitamin B 12 | 2006 |
The effects of adrenocorticotrophic hormone and cortisol on homocysteine and vitamin B concentrations.
Topics: Adrenocorticotropic Hormone; Adult; Albumins; Creatinine; Homocysteine; Humans; Hydrocortisone; Male; Reference Standards; Vitamin B 12; Vitamin B Complex | 2006 |
Vitamins and entacapone in levodopa-induced hyperhomocysteinemia: a randomized controlled study.
Topics: Aged; Antiparkinson Agents; Canada; Catechols; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Placebo Effect; Treatment Outcome; United States; Vitamin B 12; Vitamins | 2006 |
A controlled trial of homocysteine lowering and cognitive performance.
Topics: Aged; Cognition; Cognition Disorders; Dementia; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mental Status Schedule; Psychological Tests; Vitamin B 12; Vitamin B Complex | 2006 |
Effect of oral vitamin B-12 with or without folic acid on cognitive function in older people with mild vitamin B-12 deficiency: a randomized, placebo-controlled trial.
Topics: Administration, Oral; Aged; Aged, 80 and over; Cognition; Cognition Disorders; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Male; Memory; Methylmalonic Acid; Psychomotor Performance; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: A randomized, placebo-controlled, double-blind trial.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Proportional Hazards Models; Pulmonary Embolism; Pyridoxine; Recurrence; Risk Factors; Thrombophilia; Treatment Failure; Venous Thrombosis; Vitamin B 12 | 2007 |
B-vitamin status and concentrations of homocysteine in Austrian omnivores, vegetarians and vegans.
Topics: Adult; Aged; Alcohol Drinking; Anthropometry; Aspartate Aminotransferases; Austria; Diet; Diet, Vegetarian; Feeding Behavior; Female; Folic Acid; Glutathione Reductase; Homocysteine; Humans; Hyperhomocysteinemia; Male; Meat; Middle Aged; Pyridoxal Phosphate; Pyridoxic Acid; Riboflavin; Riboflavin Deficiency; Surveys and Questionnaires; Thiamine; Transketolase; Vegetables; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2006 |
Homocysteine but not neopterin declines in demented patients on B vitamins.
Topics: Dementia; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Neopterin; Thiamine; Vitamin B 12; Vitamin B 6; Vitamins | 2006 |
Effects of low- or high-dose hormone therapy on fasting and post-methionine homocysteine levels in postmenopausal women.
Topics: Dose-Response Relationship, Drug; Estradiol; Estrogen Replacement Therapy; Fasting; Female; Folic Acid; Homocysteine; Humans; Methionine; Middle Aged; Norethindrone; Postmenopause; Prospective Studies; Risk Factors; Treatment Outcome; Vitamin B 12 | 2006 |
Effects of soy isoflavones and phytate on homocysteine, C-reactive protein, and iron status in postmenopausal women.
Topics: Aged; Biomarkers; Body Mass Index; C-Reactive Protein; Coronary Artery Disease; Double-Blind Method; Female; Ferritins; Folic Acid; Homocysteine; Humans; Iron; Isoflavones; Lipids; Middle Aged; Oxidative Stress; Phytic Acid; Plant Proteins, Dietary; Postmenopause; Regression Analysis; Risk Factors; Soybean Proteins; Transferrin; Vitamin B 12 | 2006 |
Effect of short-term folate and vitamin B supplementation on blood homocysteine level and carotid artery wall thickness in chronic hemodialysis patients.
Topics: Atherosclerosis; Carotid Arteries; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Treatment Outcome; Ultrasonography; Vitamin B 12; Vitamin B 6 | 2006 |
Homocysteine reduction by B-vitamin supplementation increases t-PA and PAI-1 levels in patients with venous thromboembolism.
Topics: Adolescent; Adult; Aged; Dietary Supplements; Double-Blind Method; Drug Combinations; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Middle Aged; Plasminogen Activator Inhibitor 1; Pulmonary Embolism; Pyridoxine; Time Factors; Tissue Plasminogen Activator; Treatment Outcome; Venous Thrombosis; Vitamin B 12; Vitamin B Complex | 2007 |
Effect of fortified spread on homocysteine concentration in apparently healthy volunteers.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Homocysteine, MTHFR C677 T, vitamin B12, and folate levels in Thai children with ischemic stroke: a case-control study.
Topics: Adolescent; Child; Child, Preschool; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Ischemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Polymorphism, Single Nucleotide; Retrospective Studies; Risk Factors; Stroke; Thailand; Thrombosis; Vitamin B 12 | 2006 |
Oral vitamin B12 supplementation reduces plasma total homocysteine concentration in women in India.
Topics: Administration, Oral; Adult; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Middle Aged; Prevalence; Treatment Outcome; Vegetables; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2007 |
Lowering homocysteine with B vitamins has no effect on biomarkers of bone turnover in older persons: a 2-y randomized controlled trial.
Topics: Aged; Aged, 80 and over; Biomarkers; Bone and Bones; Bone Remodeling; Female; Homocysteine; Humans; Male; Vitamin B 12; Vitamin B 6 | 2007 |
Plasma homocysteine levels in patients treated with levodopa: motor and cognitive associations.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Case-Control Studies; Cognition; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Middle Aged; Motor Activity; Neuropsychological Tests; Parkinson Disease; Statistics, Nonparametric; Vitamin B 12 | 2006 |
Plasma homocysteine, folate, and vitamin B 12 and the risk of hip fracture: the hordaland homocysteine study.
Topics: Adult; Aged; Biomarkers; Female; Folic Acid; Follow-Up Studies; Hip Fractures; Homocysteine; Humans; Male; Middle Aged; Osteoporosis; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prospective Studies; Risk Factors; Vitamin B 12 | 2007 |
Fortified mineral water improves folate status and decreases plasma homocysteine concentration in pregnant women.
Topics: Adult; Calcium; Dietary Supplements; Double-Blind Method; Female; Finland; Folic Acid; Homocysteine; Humans; Mineral Waters; Pregnancy; Prenatal Care; Vitamin B 12; Vitamin B 6; Vitamin D | 2007 |
Oestrogen replacement therapy reduces total plasma homocysteine and enhances genomic DNA methylation in postmenopausal women.
Topics: Cross-Over Studies; DNA Methylation; Double-Blind Method; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Replacement Therapy; Female; Folic Acid; Genes, p16; Homocysteine; Humans; Middle Aged; Postmenopause; Vitamin B 12; Vitamin B 6 | 2007 |
Homocysteine levels are unaffected by metformin treatment in both nonpregnant and pregnant women with polycystic ovary syndrome.
Topics: Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Metformin; Methylenetetrahydrofolate Reductase (NADPH2); Polycystic Ovary Syndrome; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Prospective Studies; Testosterone; Vitamin B 12 | 2007 |
[Effects of intervention therapy of methylcobalamin and folic acid on plasma homocysteine concentration and homocysteine thiolactonases/paraoxonase activity in patients with type 2 diabetes mellitus].
Topics: Administration, Oral; Adult; Aged; Aryldialkylphosphatase; Carboxylic Ester Hydrolases; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Injections, Intramuscular; Middle Aged; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2007 |
Lowering homocysteine with B vitamins has no effect on blood pressure in older adults.
Topics: Aged; Blood Pressure; Diastole; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Osmolar Concentration; Systole; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Measures of adiposity and body fat distribution in relation to serum folate levels in postmenopausal women in a feeding study.
Topics: Absorptiometry, Photon; Adipose Tissue; Adiposity; Aged; Alcohol Drinking; Body Composition; Body Mass Index; Cross-Over Studies; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Multivariate Analysis; Obesity; Overweight; Postmenopause; Vitamin B 12 | 2008 |
Homocysteine, folate and cobalamin levels in hypothyroid women before and after treatment.
Topics: Adult; Creatine; Female; Folic Acid; Homocysteine; Humans; Hypothyroidism; Middle Aged; Thyrotropin; Thyroxine; Vitamin B 12 | 2007 |
The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people.
Topics: Aged; Attention; Betaine; Choline; Cognition; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Memory; Neuropsychological Tests; Psychomotor Performance; Sarcosine; Vitamin B 12; Vitamin B Complex | 2007 |
Homocysteine-lowering therapy does not affect inflammatory markers of atherosclerosis in patients with stable coronary artery disease.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; CD40 Ligand; Cholesterol, LDL; Coronary Artery Disease; Double-Blind Method; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Interleukin-6; Male; Middle Aged; Neopterin; Prospective Studies; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Folic acid and vitamin B-12 supplementation does not favorably influence uracil incorporation and promoter methylation in rectal mucosa DNA of subjects with previous colorectal adenomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; DNA Methylation; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Intestinal Mucosa; Male; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Promoter Regions, Genetic; Uracil; Vitamin B 12 | 2007 |
Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and end-stage renal disease: a randomized controlled trial.
Topics: Aged; Cause of Death; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Kaplan-Meier Estimate; Kidney Failure, Chronic; Male; Middle Aged; Proportional Hazards Models; Pyridoxine; Renal Insufficiency, Chronic; Vascular Diseases; Vitamin B 12; Vitamin B Complex | 2007 |
Pemetrexed pharmacokinetics and pharmacodynamics in a phase I/II study of doublet chemotherapy with vinorelbine: implications for further optimisation of pemetrexed schedules.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma, Non-Small-Cell Lung; Deoxyuridine; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Glutamates; Guanine; Homocysteine; Humans; Lung Neoplasms; Male; Methylmalonic Acid; Middle Aged; Pemetrexed; Thymidine; Thymidylate Synthase; Vinblastine; Vinorelbine; Vitamin B 12 | 2007 |
[Clinical studies on fifty-seven Chinese patients with combined methylmalonic aciduria and homocysteinemia].
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Anemia; Carnitine; Child; Child, Preschool; China; Female; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Metabolic Diseases; Methylmalonic Acid; Urologic Diseases; Vitamin B 12; Vitamin B Complex; Young Adult | 2007 |
Randomized clinical trial of homocysteine level lowering therapy and fractures.
Topics: Aged; Cardiovascular Diseases; Drug Therapy, Combination; Female; Folic Acid; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Proportional Hazards Models; Pyridoxine; Risk Factors; Treatment Outcome; Vitamin B 12 | 2007 |
Study of the effectiveness of additional reductions in cholesterol and homocysteine (SEARCH): characteristics of a randomized trial among 12064 myocardial infarction survivors.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Cholesterol; Dose-Response Relationship, Drug; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Myocardial Infarction; Retrospective Studies; Simvastatin; Survival Rate; Time Factors; Treatment Outcome; United Kingdom; Vitamin B 12; Vitamin B Complex | 2007 |
Cobalamin and folate status in infants and young children in a low-to-middle income community in India.
Topics: Child, Preschool; Double-Blind Method; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; India; Infant; Male; Methylmalonic Acid; Nutritional Status; Socioeconomic Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Homocysteine lowering with folic acid and B vitamins in people with chronic kidney disease--results of the renal Hope-2 study.
Topics: Aged; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Male; Vitamin B 12; Vitamin B 6 | 2008 |
The effect of B-vitamins on biochemical bone turnover markers and bone mineral density in osteoporotic patients: a 1-year double blind placebo controlled trial.
Topics: Aged; Aged, 80 and over; Biomarkers; Bone Density; Bone Remodeling; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Osteoporosis; Placebos; Vitamin B 12; Vitamin B Complex | 2007 |
Age-related hearing loss, methylmalonic acid, and vitamin B12 status in older adults.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Cohort Studies; Creatinine; Dietary Supplements; Dose-Response Relationship, Drug; Female; Geriatric Assessment; Hearing Loss; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Nutritional Status; Socioeconomic Factors; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2006 |
Efficacy of multivitamin supplementation containing vitamins B6 and B12 and folic acid as adjunctive treatment with a cholinesterase inhibitor in Alzheimer's disease: a 26-week, randomized, double-blind, placebo-controlled study in Taiwanese patients.
Topics: Aged; Alzheimer Disease; Asian People; Cholinesterase Inhibitors; Donepezil; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Indans; Male; Piperidines; Taiwan; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Fluorouracil-based chemotherapy in patients with gastrointestinal malignancies: influence of nutritional folate status on toxicity.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Folic Acid; Gastrointestinal Neoplasms; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12 | 2007 |
Lowering plasma homocysteine concentrations of older men and women with folate, vitamin B-12, and vitamin B-6 does not affect the proportion of (n-3) long chain polyunsaturated fatty acids in plasma phosphatidylcholine.
Topics: Aged; Double-Blind Method; Fatty Acids, Omega-3; Female; Folic Acid; Homocysteine; Humans; Male; Phosphatidylcholines; Time Factors; Vitamin B 12; Vitamin B 6 | 2008 |
Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease: a randomized trial.
Topics: Adult; Aged; Cardiovascular Diseases; Dietary Supplements; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Risk; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Common metabolic profile in infants indicating impaired cobalamin status responds to cobalamin supplementation.
Topics: Breast Feeding; Dietary Supplements; Folic Acid; Homocysteine; Humans; Infant; Linear Models; Methylmalonic Acid; Vitamin B 12 | 2008 |
Plasma homocysteine level is elevated in patients on isotretinoin therapy for cystic acne: a prospective controlled study.
Topics: Acne Vulgaris; Adolescent; Adult; Dermatologic Agents; Female; Folic Acid; Homocysteine; Humans; Isotretinoin; Liver Function Tests; Male; Prospective Studies; Vitamin B 12; Young Adult | 2008 |
Weekly may be as efficacious as daily folic acid supplementation in improving folate status and lowering serum homocysteine concentrations in Guatemalan women.
Topics: Adolescent; Adult; Dietary Supplements; Double-Blind Method; Drug Administration Schedule; Female; Folic Acid; Guatemala; Homocysteine; Humans; Middle Aged; Vitamin B 12; Vitamins | 2008 |
Bread cofortified with folic acid and vitamin B-12 improves the folate and vitamin B-12 status of healthy older people: a randomized controlled trial.
Topics: Aged; Aging; Bread; Double-Blind Method; Erythrocytes; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Neural Tube Defects; Nutritional Requirements; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Consumption of restructured meat products with added walnuts has a cholesterol-lowering effect in subjects at high cardiovascular risk: a randomised, crossover, placebo-controlled study.
Topics: Aged; Animals; Cardiovascular Diseases; Cattle; Cholesterol; Cross-Over Studies; Female; Folic Acid; gamma-Tocopherol; Homocysteine; Humans; Juglans; Lipoproteins, HDL; Lipoproteins, LDL; Male; Meat Products; Middle Aged; Platelet Function Tests; Postprandial Period; Triglycerides; Vitamin B 12; Vitamin B 6 | 2008 |
Mortality and cardiovascular events in patients treated with homocysteine-lowering B vitamins after coronary angiography: a randomized controlled trial.
Topics: Aged; Aortic Valve Stenosis; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Effect of folic acid combined with fluoxetine in patients with major depression on plasma homocysteine and vitamin B12, and serotonin levels in lymphocytes.
Topics: Adult; Chromatography, High Pressure Liquid; Depressive Disorder, Major; Down-Regulation; Drug Synergism; Drug Therapy, Combination; Female; Fluoxetine; Folic Acid; Homocysteine; Humans; Lymphocytes; Male; Middle Aged; Neuropsychological Tests; Selective Serotonin Reuptake Inhibitors; Serotonin; Severity of Illness Index; Treatment Outcome; Vitamin B 12; Vitamin B Complex; Young Adult | 2008 |
Effects of plasma homocysteine levels on serum HTase/PON activity in patients with type 2 diabetes.
Topics: Adult; Aged; Aryldialkylphosphatase; Carboxylic Ester Hydrolases; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12; Vitamins | 2008 |
Randomized placebo-controlled trial assessing a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on plasma asymmetric dimethylarginine concentration in mild to moderate CKD.
Topics: Adult; Aged; Anticholesteremic Agents; Arginine; Carotid Arteries; Chronic Disease; Creatinine; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Kidney Diseases; Lipoproteins, LDL; Male; Middle Aged; Pravastatin; Vitamin B 12; Vitamin B 6; Vitamin E | 2009 |
Alcohol increases homocysteine and reduces B vitamin concentration in healthy male volunteers--a randomized, crossover intervention study.
Topics: Adult; Aged; Alcohol Drinking; Cross-Over Studies; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Vitamin B 12; Young Adult | 2008 |
The effect of long-term homocysteine-lowering on carotid intima-media thickness and flow-mediated vasodilation in stroke patients: a randomized controlled trial and meta-analysis.
Topics: Aged; Carotid Arteries; Dietary Supplements; Double-Blind Method; Down-Regulation; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Regional Blood Flow; Stroke; Time Factors; Treatment Outcome; Tunica Intima; Tunica Media; Vasodilation; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cognition Disorders; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Psychiatric Status Rating Scales; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Correlations between plasma homocysteine and folate concentrations and carotid atherosclerosis in high-risk individuals: baseline data from the Homocysteine and Atherosclerosis Reduction Trial (HART).
Topics: Aged; Biomarkers; Calcinosis; Canada; Cardiovascular Diseases; Carotid Artery Diseases; Carotid Artery, Common; Disease Progression; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Prospective Studies; Risk Factors; Tunica Intima; Tunica Media; Ultrasonography; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Long-term garlic or micronutrient supplementation, but not anti-Helicobacter pylori therapy, increases serum folate or glutathione without affecting serum vitamin B-12 or homocysteine in a rural Chinese population.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Asian People; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Garlic; Glutathione; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Male; Micronutrients; Middle Aged; Omeprazole; Rural Population; Vitamin B 12 | 2009 |
A trial of B vitamins and cognitive function among women at high risk of cardiovascular disease.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Chi-Square Distribution; Cognition; Cognition Disorders; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Psychometrics; Risk Factors; Statistics, Nonparametric; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Plasma Abeta, homocysteine, and cognition: the Vitamin Intervention for Stroke Prevention (VISP) trial.
Topics: Aged; Amyloid beta-Peptides; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Down-Regulation; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Osmolar Concentration; Peptide Fragments; Pyridoxine; Stroke; Treatment Failure; Vitamin B 12; Vitamin B Complex; Vitamins | 2009 |
Clinical trial: B vitamins improve health in patients with coeliac disease living on a gluten-free diet.
Topics: Anxiety; Celiac Disease; Depressive Disorder; Diet, Gluten-Free; Female; Folic Acid; Health Status; Homocysteine; Humans; Male; Middle Aged; Pyridoxine; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex | 2009 |
Effect of long-term homocysteine reduction with B vitamins on arterial wall inflammation assessed by fluorodeoxyglucose positron emission tomography: a randomised double-blind, placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Aorta; Arteritis; Atherosclerosis; Brachial Artery; Carotid Arteries; Cross-Sectional Studies; Double-Blind Method; Drug Combinations; Female; Femoral Artery; Fluorodeoxyglucose F18; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Stroke; Time Factors; Treatment Outcome; Ultrasonography; Vasodilation; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2009 |
Zinc supplementation does not alter plasma homocysteine, vitamin B12 and red blood cell folate concentrations in French elderly subjects.
Topics: Age Factors; Aged; Dietary Supplements; Erythrocytes; Female; Folic Acid; France; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12; Zinc | 2009 |
Homocysteine-lowering therapy and stroke risk, severity, and disability: additional findings from the HOPE 2 trial.
Topics: Aged; Disability Evaluation; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kaplan-Meier Estimate; Male; Middle Aged; Risk Factors; Severity of Illness Index; Stroke; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamins | 2009 |
Preliminary evidence for cell membrane amelioration in children with cystic fibrosis by 5-MTHF and vitamin B12 supplementation: a single arm trial.
Topics: Antiporters; Cations; Child; Child, Preschool; Cystic Fibrosis; Dietary Supplements; Erythrocyte Membrane; Erythrocytes; Female; Homocysteine; HSP70 Heat-Shock Proteins; Humans; Ion Transport; Male; Malondialdehyde; Membrane Fluidity; Membrane Lipids; Oxidative Stress; Phospholipids; Tetrahydrofolates; Vitamin B 12 | 2009 |
Dietary and supplementary betaine: effects on betaine and homocysteine concentrations in males.
Topics: Adult; Betaine; Biomarkers; Choline; Creatinine; Cross-Over Studies; Diet; Dietary Supplements; Folic Acid; Homocysteine; Humans; Lipids; Male; Sarcosine; Time Factors; Vitamin B 12; Young Adult | 2009 |
Effect of Sclerovit on endothelial dysfunction, hemorheological parameters, platelet aggregation, plasma concentration of homocysteine and progression of atherosclerosis in patients with vascular diseases.
Topics: Aged; Atherosclerosis; Carotid Stenosis; Drug Combinations; Erythrocyte Deformability; Female; Folic Acid; Hemorheology; Homocysteine; Humans; Male; Middle Aged; Platelet Aggregation; Tunica Intima; Tunica Media; Vasodilation; Vitamin B 12; Vitamin B 6; Vitamin E; von Willebrand Factor | 2009 |
The effects of vitamin supplementation and MTHFR (C677T) genotype on homocysteine-lowering and migraine disability.
Topics: Double-Blind Method; Female; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Migraine Disorders; Vitamin B 12; Vitamin B 6 | 2009 |
Effect of homocysteine-lowering treatment with folic Acid and B vitamins on risk of type 2 diabetes in women: a randomized, controlled trial.
Topics: Adult; Aged; Ascorbic Acid; beta Carotene; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Middle Aged; Placebos; Proportional Hazards Models; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin E | 2009 |
Influence of folic acid on plasma homocysteine levels & arterial endothelial function in patients with unstable angina.
Topics: Acute Coronary Syndrome; Adult; Aged; Angina, Unstable; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Vasodilation; Vitamin B 12; Vitamin B Complex | 2009 |
Efficacy of folate and vitamin B12 in lowering homocysteine concentrations in hemodialysis patients.
Topics: Administration, Oral; Adult; Aged; Biomarkers; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutritional Status; Prospective Studies; Renal Dialysis; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2009 |
Serum homocysteine, folate and vitamin B12 in patients with Paget's disease of bone: the effect of zoledronic acid.
Topics: 25-Hydroxyvitamin D 2; Aged; Alkaline Phosphatase; Biomarkers; Body Mass Index; Bone Density Conservation Agents; Bone Neoplasms; Bone Remodeling; Calcifediol; Cohort Studies; Collagen Type I; Diphosphonates; Female; Folic Acid; Homocysteine; Humans; Imidazoles; Isoenzymes; Male; Paget Disease, Extramammary; Peptides; Pilot Projects; Time Factors; Vitamin B 12; Zoledronic Acid | 2010 |
Homocysteine-lowering vitamins do not lower plasma S-adenosylhomocysteine in older people with elevated homocysteine concentrations.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vascular Diseases; Vitamin B 12; Vitamin B 6; Vitamins | 2010 |
Novel pro-atherogenic molecule coupling factor 6 is elevated in patients with stroke: a possible linkage to homocysteine.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Japan; Male; Middle Aged; Mitochondrial Proton-Translocating ATPases; Oxidative Phosphorylation Coupling Factors; Stroke; Vitamin B 12; Vitamin B Complex | 2010 |
The B-VITAGE trial: a randomized trial of homocysteine lowering treatment of depression in later life.
Topics: Age Factors; Antidepressive Agents; Biomarkers; Citalopram; Depression; Double-Blind Method; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Medication Adherence; Middle Aged; Psychiatric Status Rating Scales; Research Design; Severity of Illness Index; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Western Australia | 2010 |
Supplementation with a multivitamin containing 800 microg of folic acid shortens the time to reach the preventive red blood cell folate concentration in healthy women.
Topics: Adolescent; Adult; Diet; Diet Records; Dietary Supplements; Double-Blind Method; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Methionine; Micronutrients; Neural Tube Defects; Nutritional Status; Reference Values; Riboflavin; Time Factors; Vitamin B 12; Vitamin B 6; Young Adult | 2009 |
Effect of a Klamath algae product ("AFA-B12") on blood levels of vitamin B12 and homocysteine in vegan subjects: a pilot study.
Topics: Adult; Aphanizomenon; Biomarkers; Diet, Vegetarian; Dietary Supplements; Folic Acid; Homocysteine; Humans; Intestinal Absorption; Middle Aged; Pilot Projects; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2009 |
Long-term effects of weight loss with a very low carbohydrate and low fat diet on vascular function in overweight and obese patients.
Topics: Blood Flow Velocity; Blood Pressure; Brachial Artery; Diet, Carbohydrate-Restricted; Diet, Fat-Restricted; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Middle Aged; Obesity; Overweight; Vitamin B 12; Weight Loss | 2010 |
The status of vitamins B6, B12, folate, and of homocysteine in geriatric home residents receiving laxatives or dietary fiber.
Topics: Aged; Aged, 80 and over; Avena; Biological Availability; Constipation; Dietary Fiber; Dietary Supplements; Energy Intake; Folic Acid; Homocysteine; Humans; Laxatives; Middle Aged; Nursing Homes; Phytotherapy; Seeds; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B Complex | 2010 |
An evaluation of plasma homocysteine in the assessment of vitamin B12 status of pasture-fed sheep.
Topics: Animal Husbandry; Animal Nutritional Physiological Phenomena; Animals; Cobalt; Diet; Female; Homocysteine; Male; Nutritional Status; Sheep; Vitamin B 12; Vitamin B 12 Deficiency; Weight Gain | 2010 |
Effect of physiological doses of oral vitamin B12 on plasma homocysteine: a randomized, placebo-controlled, double-blind trial in India.
Topics: Adult; Child; Dietary Supplements; Double-Blind Method; Family; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2010 |
Randomized controlled trial of the effect of short-term coadministration of methylcobalamin and folate on serum ADMA concentration in patients receiving long-term hemodialysis.
Topics: Administration, Oral; Aged; Arginine; Cardiovascular Diseases; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Injections, Intravenous; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Risk Factors; Vitamin B 12; Vitamin B Complex | 2010 |
Pre-operative vitamin B infusion and prevention of nitrous oxide-induced homocysteine increase.
Topics: Adult; Anesthetics, Inhalation; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nitrous Oxide; Preanesthetic Medication; Prospective Studies; Vitamin B 12; Vitamin B Complex | 2010 |
Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: randomised placebo controlled trial.
Topics: Aged; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Long-Term Care; Male; Metformin; Middle Aged; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2010 |
Effect of homocysteine-lowering B vitamin treatment on angiographic progression of coronary artery disease: a Western Norway B Vitamin Intervention Trial (WENBIT) substudy.
Topics: Aged; Angioplasty, Balloon, Coronary; Biomarkers; Coronary Angiography; Coronary Artery Disease; Disease Progression; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Norway; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2010 |
Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: a randomized trial.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Morbidity; Myocardial Infarction; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2010 |
Hyperhomocysteinemia prevalence among patients with venous thromboembolism.
Topics: Adult; Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Risk Factors; Venous Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Do novel risk biomarkers reflect the severity of peripheral arterial disease?
Topics: Aged; Aged, 80 and over; Ankle Brachial Index; Biomarkers; Blood Coagulation Factors; Blood Flow Velocity; C-Reactive Protein; Female; Folic Acid; Homocysteine; Humans; Inflammation Mediators; Lipids; Male; Middle Aged; Peripheral Arterial Disease; Predictive Value of Tests; Severity of Illness Index; Vitamin B 12 | 2011 |
Effect of an antioxidant drink on homocysteine levels in Alzheimer's patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Cross-Sectional Studies; Double-Blind Method; Female; Flavonoids; Folic Acid; Homocysteine; Humans; Male; Neuropsychological Tests; Oxidative Stress; Phenols; Polyphenols; Statistics, Nonparametric; Treatment Outcome; Vitamin B 12 | 2010 |
Vitamins B(12), B(6), and folic acid for cognition in older men.
Topics: Aged; Aged, 80 and over; Cognition; Cognition Disorders; Community Health Planning; Dementia; Dietary Supplements; Double-Blind Method; Folic Acid; Follow-Up Studies; Geriatrics; Homocysteine; Humans; Male; Neuropsychological Tests; Patient Compliance; Time Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2010 |
A dose-finding trial of the effect of long-term folic acid intervention: implications for food fortification policy.
Topics: Aged; Dose-Response Relationship, Drug; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Middle Aged; Myocardial Ischemia; Neural Tube Defects; Nutrition Policy; Vitamin B 12 | 2011 |
A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Dementia, Vascular; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Hong Kong; Humans; Hyperhomocysteinemia; Male; Neuropsychological Tests; Patient Dropouts; Vitamin B 12; Vitamin B Complex | 2011 |
Oral vitamin B12 for patients suspected of subtle cobalamin deficiency: a multicentre pragmatic randomised controlled trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Blood Specimen Collection; Dietary Supplements; Female; Follow-Up Studies; Homocysteine; Humans; Least-Squares Analysis; Male; Methylmalonic Acid; Middle Aged; Patient Compliance; Switzerland; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Young Adult | 2011 |
Impact of spinach consumption on DNA stability in peripheral lymphocytes and on biochemical blood parameters: results of a human intervention trial.
Topics: Antioxidants; Blood Cells; Blood Glucose; Cholesterol, HDL; Cholesterol, LDL; Comet Assay; DNA Damage; DNA-Formamidopyrimidine Glycosylase; Endpoint Determination; Female; Folic Acid; Homocysteine; Humans; Hydrogen Peroxide; Lymphocyte Count; Lymphocytes; Male; Middle Aged; Oxidative Stress; Phytotherapy; Plant Leaves; Plant Preparations; Reactive Oxygen Species; Spinacia oleracea; Triglycerides; Vitamin A; Vitamin B 12; Vitamin E | 2011 |
Coronary blood flow in patients with stable coronary artery disease treated long term with folic acid and vitamin B12.
Topics: Acetylcholine; Adenosine; Aged; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Laser-Doppler Flowmetry; Male; Middle Aged; Time Factors; Vitamin B 12; Vitamin B 6 | 2011 |
A proteomics study reveals a predominant change in MaoB expression in platelets of healthy volunteers after high protein meat diet: relationship to the methylation cycle.
Topics: Adult; Blood Platelets; Cognition; Electrophoresis, Gel, Two-Dimensional; Fasting; Food, Fortified; Homocysteine; Humans; Male; Methylation; Monoamine Oxidase; Neuropsychological Tests; Proteins; Proteomics; Psychomotor Performance; Reaction Time; Single-Blind Method; Statistics as Topic; Statistics, Nonparametric; Up-Regulation; Vitamin B 12; Young Adult | 2011 |
Influence of diabetes on homocysteine-lowering therapy in chronic hemodialysis patients.
Topics: Biomarkers; C-Reactive Protein; Diabetes Complications; Dietary Supplements; Folic Acid; Homocysteine; Humans; Inflammation; Male; Middle Aged; Regression Analysis; Renal Dialysis; Uremia; Vitamin B 12 | 2011 |
Cobalamin status modifies the effect of zinc supplementation on the incidence of prolonged diarrhea in 6- to 30-month-old north Indian children.
Topics: Child, Preschool; Diarrhea; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Incidence; India; Infant; Male; Methylmalonic Acid; Vitamin B 12; Zinc | 2011 |
The vitamin B12 absorption test, CobaSorb, identifies patients not requiring vitamin B12 injection therapy.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Biomarkers; Blood Chemical Analysis; Female; Hemoglobins; Homocysteine; Humans; Injections; Intestinal Absorption; Male; Methylmalonic Acid; Middle Aged; Prospective Studies; Reference Values; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Maternal one-carbon metabolism, MTHFR and TCN2 genotypes and neural tube defects in India.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; India; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Cognition; Cognition Disorders; Double-Blind Method; Executive Function; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Memory; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2012 |
Effect of folic acid supplementation on homocysteine, serum total antioxidant capacity, and malondialdehyde in patients with type 2 diabetes mellitus.
Topics: Administration, Oral; Aged; Antioxidants; Diabetes Mellitus, Type 2; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Folic Acid; Homocysteine; Humans; Male; Malondialdehyde; Metformin; Middle Aged; Oxidative Stress; Vitamin B 12 | 2011 |
Implant overdentures and nutrition: a randomized controlled trial.
Topics: Aged; Dental Prosthesis, Implant-Supported; Denture, Complete, Lower; Denture, Overlay; Elder Nutritional Physiological Phenomena; Female; Folic Acid; Fruit; Homocysteine; Humans; Linear Models; Male; Mastication; Nutritional Status; Serum Albumin; Vegetables; Vitamin B 12; Vitamin B 6 | 2012 |
Poor folate status predicts persistent diarrhea in 6- to 30-month-old north Indian children.
Topics: Biomarkers; Child, Preschool; Diarrhea; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; India; Infant; Interviews as Topic; Male; Prospective Studies; Risk Factors; Treatment Outcome; Vitamin B 12 | 2011 |
Effect of isotretinoin treatment on plasma holotranscobalamin, vitamin B12, folic acid, and homocysteine levels: non-controlled study.
Topics: Acne Vulgaris; Adolescent; Adult; Alanine Transaminase; Aspartate Aminotransferases; Cholesterol; Cholesterol, LDL; Cholesterol, VLDL; Dermatologic Agents; Female; Folic Acid; Homocysteine; Humans; Isotretinoin; Male; Transcobalamins; Triglycerides; Vitamin B 12; Young Adult | 2011 |
Analysis of perinatal outcome by combination of first trimester maternal plasma homocysteine with uterine artery Doppler velocimetry.
Topics: Adult; Biomarkers; Blood Flow Velocity; Female; Fetal Growth Retardation; Folic Acid; Gestational Age; Homocysteine; Humans; Hypertension, Pregnancy-Induced; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Premature Birth; Prognosis; Prospective Studies; Rheology; Ultrasonography, Prenatal; Uterine Artery; Vitamin B 12 | 2011 |
The effect of vitamin B supplementation on homocysteine metabolism and clinical state of patients with chronic epilepsy treated with carbamazepine and valproic acid.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Dietary Supplements; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Valproic Acid; Vitamin B 12; Vitamin B Complex; Young Adult | 2012 |
Multiple micronutrient-fortified rice affects physical performance and plasma vitamin B-12 and homocysteine concentrations of Indian school children.
Topics: Anemia; Child; Child Nutrition Disorders; Cognition; Educational Status; Female; Food Services; Food, Fortified; Homocysteine; Humans; India; Iron; Male; Micronutrients; Morbidity; Motor Activity; Oryza; Prevalence; Schools; Vitamin B 12 | 2012 |
Vitamin B-12 supplementation improves arterial function in vegetarians with subnormal vitamin B-12 status.
Topics: Adult; Arteries; Biomarkers; Brachial Artery; Carotid Arteries; Carotid Intima-Media Thickness; Cross-Over Studies; Diet, Vegetarian; Dietary Supplements; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Hong Kong; Humans; Male; Middle Aged; Vasodilation; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Effects of a multivitamin, mineral and herbal supplement on cognition and blood biomarkers in older men: a randomised, placebo-controlled trial.
Topics: Aged; Biomarkers; Cognition; Dietary Supplements; Double-Blind Method; Folic Acid; Homocysteine; Humans; Male; Memory; Memory, Episodic; Middle Aged; Minerals; Nutritional Status; Phytotherapy; Risk Factors; Sedentary Behavior; Vitamin B 12; Vitamins | 2012 |
Vitamin B-12 supplementation of rural Mexican women changes biochemical vitamin B-12 status indicators but does not affect hematology or a bone turnover marker.
Topics: Adult; Alkaline Phosphatase; Bone Remodeling; C-Reactive Protein; Dietary Supplements; Female; Ferritins; Folic Acid; Homocysteine; Humans; Logistic Models; Methylmalonic Acid; Mexico; Middle Aged; Nutritional Status; Rural Population; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Young Adult | 2012 |
Vitamin B12 level in peripheral arterial disease.
Topics: Aged; Amino Acid Substitution; Female; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Peripheral Arterial Disease; Polymorphism, Genetic; Risk Factors; Vitamin B 12 | 2013 |
Effects of red wine polyphenols and alcohol on glucose metabolism and the lipid profile: a randomized clinical trial.
Topics: Adipokines; Aged; Apolipoproteins; Blood Glucose; Cardiovascular Diseases; Cholesterol; Cross-Over Studies; Diet; Ethanol; Fasting; Folic Acid; Glucose; Homeostasis; Homocysteine; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Polyphenols; Risk Factors; Triglycerides; Vitamin B 12; Wine | 2013 |
Cobalamin and folate status predicts mental development scores in North Indian children 12-18 mo of age.
Topics: Biomarkers; Child Development; Cognition Disorders; Cohort Studies; Developmental Disabilities; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; India; Infant; Male; Methylmalonic Acid; Neurogenesis; Nutritional Status; Prevalence; Psychomotor Performance; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
[Correlation between long-term proton pump ingibitor use, homocysteine and lipoproteins serum concentrations in patients with comorbidity of ischemic heart disease and acid peptic disease].
Topics: Cholesterol; Comorbidity; Dyslipidemias; Homocysteine; Humans; Hyperhomocysteinemia; Infusions, Parenteral; Lipoproteins, LDL; Myocardial Ischemia; Peptic Ulcer; Proton Pump Inhibitors; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
[Impact of adding folic acid, vitamin B(12) and probucol to standard antihypertensive medication on plasma homocysteine and asymmetric dimethylarginine levels of essential hypertension patients].
Topics: Aged; Antihypertensive Agents; Arginine; Female; Folic Acid; Homocysteine; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type III; Plasma; Probucol; Vitamin B 12; Vitamin B Complex; Vitamins | 2012 |
The contribution of portal drained viscera to circadian homocysteinemia in pigs.
Topics: Animals; Circadian Rhythm; Dose-Response Relationship, Drug; Homocysteine; Hyperhomocysteinemia; Portal Vein; Swine; Swine Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Vitamin B12 and homocysteine status during pregnancy in the metformin in gestational diabetes trial: responses to maternal metformin compared with insulin treatment.
Topics: Adult; Biomarkers; Cohort Studies; Diabetes, Gestational; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Metformin; Nutritional Status; Postpartum Period; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Pregnancy Trimester, Third; South Australia; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Folate catabolites in spot urine as non-invasive biomarkers of folate status during habitual intake and folic acid supplementation.
Topics: Adult; Dietary Supplements; Folic Acid; Glutamates; Homocysteine; Humans; Male; Urinalysis; Vitamin B 12; Vitamin B 6; Young Adult | 2013 |
The China Stroke Secondary Prevention Trial (CSSPT) protocol: a double-blinded, randomized, controlled trial of combined folic acid and B vitamins for secondary prevention of stroke.
Topics: Adult; Aged; Brain Ischemia; China; Double-Blind Method; Folic Acid; Homocysteine; Humans; Intracranial Hemorrhage, Hypertensive; Middle Aged; Myocardial Infarction; Protective Agents; Research Design; Secondary Prevention; Stroke; Vitamin B 12; Vitamin B 6 | 2015 |
Folic acid and vitamin B(12) supplementation lowers plasma homocysteine but has no effect on serum bone turnover markers in elderly women: a randomized, double-blind, placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Biomarkers; Bone Remodeling; Collagen Type I; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Peptides; Placebos; Vitamin B 12 | 2013 |
Effects of mixed dietary supplements on total plasma homocysteine concentrations (tHcy): a randomized, double-blind, placebo-controlled trial.
Topics: Acute Disease; Aged; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Hospitalization; Humans; Male; Placebos; Riboflavin; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2012 |
Homocysteine and the methylenetetrahydrofolate reductase 677C-->T polymorphism in relation to muscle mass and strength, physical performance and postural sway.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Body Composition; Creatinine; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Genotype; Hand Strength; Homocysteine; Humans; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Motor Activity; Muscle, Skeletal; Polymorphism, Single Nucleotide; Postural Balance; Treatment Outcome; Vitamin B 12 | 2013 |
The effects of nitrous oxide on vitamin B12 and homocysteine levels in methyltetrahydrofolate reductase gene mutation.
Topics: Adult; Double-Blind Method; Female; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Nitrous Oxide; Polymorphism, Genetic; Prospective Studies; Vitamin B 12 | 2013 |
Effect of B vitamins and lowering homocysteine on cognitive impairment in patients with previous stroke or transient ischemic attack: a prespecified secondary analysis of a randomized, placebo-controlled trial and meta-analysis.
Topics: Aged; Cognition Disorders; Double-Blind Method; Female; Follow-Up Studies; Homocysteine; Humans; Ischemic Attack, Transient; Male; Middle Aged; Placebos; Recurrence; Stroke; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2013 |
Extending the homocysteine-induced neurotransmitter deficiency and depression of mood hypothesis to quality of life in older patients.
Topics: Aged; Aged, 80 and over; Dietary Supplements; Double-Blind Method; Female; Homocysteine; Humans; Male; Mood Disorders; Quality of Life; Riboflavin; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2013 |
Vitamin B12 level may be related to the efficacy of single ketamine infusion in bipolar depression.
Topics: Adult; Aged; Bipolar Disorder; Excitatory Amino Acid Antagonists; Female; Folic Acid; Homocysteine; Humans; Infusions, Intravenous; Ketamine; Male; Middle Aged; Vitamin B 12 | 2013 |
Daily milk intake improves vitamin B-12 status in young vegetarian Indians: an intervention trial.
Topics: Adult; Animals; Buffaloes; Diet, Fat-Restricted; Diet, Vegetarian; Female; Functional Food; Health Promotion; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Milk; Nutrition Policy; Nutritional Sciences; Nutritional Status; Patient Education as Topic; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Association of low baseline levels of erythrocyte folate with treatment nonresponse at three months in rheumatoid arthritis patients receiving methotrexate.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Drug Monitoring; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Predictive Value of Tests; Prospective Studies; Vitamin B 12; Vitamin B 6 | 2013 |
Short-term creatine supplementation does not reduce increased homocysteine concentration induced by acute exercise in humans.
Topics: Adolescent; Creatine; Cysteine; Dietary Supplements; Double-Blind Method; Energy Intake; Exercise; Feeding Behavior; Folic Acid; Glycine; Healthy Volunteers; Homocysteine; Humans; Male; Methionine; S-Adenosylmethionine; Soccer; Vitamin B 12 | 2014 |
Three-month B vitamin supplementation in pre-school children affects folate status and homocysteine, but not cognitive performance.
Topics: Biomarkers; Calcium, Dietary; Child; Child, Preschool; Cognition; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Germany; Homocysteine; Humans; Male; Memory, Short-Term; Methylmalonic Acid; Vitamin B 12; Vitamin B Complex | 2014 |
Influence of dialysis techniques and alternate vitamin supplementation on homocysteine levels in patients with known MTHFR genotypes.
Topics: Adult; Aged; Aged, 80 and over; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Genotype; Hemodiafiltration; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Renal Dialysis; Vitamin B 12; Vitamins; Young Adult | 2015 |
B-vitamin levels and genetics of hyperhomocysteinemia are not associated with arterial stiffness.
Topics: Aged; Aged, 80 and over; Blood Pressure; Body Mass Index; Creatinine; Cross-Sectional Studies; Double-Blind Method; Female; Folic Acid; Genotyping Techniques; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Methylmalonic Acid; Multivariate Analysis; Pulse Wave Analysis; Risk Factors; Vascular Stiffness; Vitamin B 12; Vitamin B Complex | 2014 |
Supplementation of folic acid and vitamin B₁₂ reduces plasma levels of asymmetric dimethylarginine in patients with acute ischemic stroke.
Topics: Aged; Arginine; Blood Chemical Analysis; Brain Ischemia; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Stroke; Time Factors; Treatment Outcome; Vitamin B 12 | 2014 |
Low-dose B vitamins supplementation ameliorates cardiovascular risk: a double-blind randomized controlled trial in healthy Chinese elderly.
Topics: Aged; Asian People; Blood Pressure; Body Mass Index; Cardiovascular Diseases; China; Cholesterol, HDL; Cholesterol, LDL; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Triglycerides; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2015 |
B vitamin supplementation improves cognitive function in the middle aged and elderly with hyperhomocysteinemia.
Topics: Aged; Aged, 80 and over; Aging; China; Cognitive Dysfunction; Dietary Supplements; Elder Nutritional Physiological Phenomena; Female; Folic Acid; Follow-Up Studies; Homes for the Aged; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nursing Homes; Prevalence; Psychiatric Status Rating Scales; Risk Factors; Vitamin B 12; Vitamin B 6 | 2016 |
The one-carbon-cycle and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in recurrent major depressive disorder; influence of antidepressant use and depressive state?
Topics: Adult; Antidepressive Agents; Carbon; Case-Control Studies; Depressive Disorder, Major; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Recurrence; Vitamin B 12; Vitamin B 6 | 2014 |
Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals with an elevated plasma homocysteine concentration: B-PROOF, a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Endpoint Determination; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Motor Activity; Netherlands; Osteoporotic Fractures; Risk Factors; Treatment Outcome; Vitamin B 12 | 2014 |
Homocysteine metabolism, growth performance, and immune responses in suckling and weanling piglets.
Topics: Age Factors; Animals; Cell Proliferation; Concanavalin A; Diet; Female; Homocysteine; Interleukin-8; Lactation; Lymphocytes; Pregnancy; Sus scrofa; Swine; Vitamin B 12; Weaning | 2015 |
Impact of personalized diet and probiotic supplementation on inflammation, nutritional parameters and intestinal microbiota - The "RISTOMED project": Randomized controlled trial in healthy older people.
Topics: Aged; Aged, 80 and over; Biological Products; Biomarkers; Blood Glucose; C-Reactive Protein; Cholesterol; Diet; Dietary Supplements; Feeding Behavior; Female; Folic Acid; Gastrointestinal Microbiome; Homocysteine; Humans; Inflammation; Intestines; Lactobacillus; Lactobacillus delbrueckii; Lactobacillus plantarum; Male; Oxidative Stress; Probiotics; Streptococcus thermophilus; Vitamin B 12 | 2015 |
Vitamin B12 supplementation during pregnancy and postpartum improves B12 status of both mothers and infants but vaccine response in mothers only: a randomized clinical trial in Bangladesh.
Topics: Adolescent; Adult; Bangladesh; Biomarkers; C-Reactive Protein; Dietary Supplements; Dose-Response Relationship, Drug; Female; Ferritins; Folic Acid; Hemoglobins; Homocysteine; Humans; Immunoglobulin A; Infant; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Lactation; Maternal Nutritional Physiological Phenomena; Methylmalonic Acid; Milk, Human; Orosomucoid; Postpartum Period; Pregnancy; Receptors, Transferrin; Vitamin B 12; Young Adult | 2016 |
Effect of Vitamin B12 and Folic Acid Supplementation on Bone Mineral Density and Quantitative Ultrasound Parameters in Older People with an Elevated Plasma Homocysteine Level: B-PROOF, a Randomized Controlled Trial.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Bone Density; Calcaneus; Dietary Supplements; Double-Blind Method; Female; Femur Neck; Folic Acid; Homocysteine; Humans; Male; Osteoporosis; Ultrasonography; Vitamin B 12 | 2015 |
Zinc supplementation influences genomic stability biomarkers, antioxidant activity, and zinc transporter genes in an elderly Australian population with low zinc status.
Topics: Aged; Aged, 80 and over; Antioxidants; Australia; Biomarkers; Body Mass Index; Carnosine; Cation Transport Proteins; Comet Assay; Dietary Supplements; DNA Damage; Female; Folic Acid; Gene Expression Regulation; Genomic Instability; Healthy Volunteers; Homocysteine; Humans; Male; Metallothionein; Micronutrients; Nutrition Assessment; Superoxide Dismutase; Telomere; Vitamin B 12; Zinc | 2015 |
Neuroprotective impact of a vitamin trace element composition - a randomized, double blind, placebo controlled clinical trial with healthy volunteers.
Topics: Adult; Aged; Double-Blind Method; Female; Folic Acid; Healthy Volunteers; Homocysteine; Humans; Lipid Peroxidation; Male; Middle Aged; Neuroprotective Agents; Pyridoxine; Superoxide Dismutase; Tocopherols; Trace Elements; Vitamin B 12; Vitamins | 2015 |
Vitamin B-12 Status Differs among Pregnant, Lactating, and Control Women with Equivalent Nutrient Intakes.
Topics: Adult; Biomarkers; Breast Feeding; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Energy Intake; Female; Healthy Volunteers; Homocysteine; Humans; Lactation; Methylmalonic Acid; Micronutrients; Postpartum Period; Pregnancy; Recommended Dietary Allowances; Vitamin B 12; Young Adult | 2015 |
Improved blood biomarkers but no cognitive effects from 16 weeks of multivitamin supplementation in healthy older adults.
Topics: Aged; Aging; Biomarkers; C-Reactive Protein; Cognition; Cognition Disorders; Dietary Supplements; Double-Blind Method; Female; Homocysteine; Humans; Lipids; Male; Middle Aged; Oxidative Stress; Reference Values; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamins | 2015 |
Effect of different doses of isotretinoin treatment on the levels of serum homocysteine, vitamin B 12 and folic acid in patients with acne vulgaris: A prospective controlled study.
Topics: Acne Vulgaris; Biomarkers; Case-Control Studies; Dermatologic Agents; Female; Folic Acid; Homocysteine; Humans; Isotretinoin; Male; Prospective Studies; Treatment Outcome; Turkey; Vitamin B 12; Young Adult | 2015 |
A Randomized Controlled Trial to Examine the Effect of 2-Year Vitamin B12 and Folic Acid Supplementation on Physical Performance, Strength, and Falling: Additional Findings from the B-PROOF Study.
Topics: Accidental Falls; Aged; Aged, 80 and over; Aging; Dietary Supplements; Female; Folic Acid; Hand Strength; Homocysteine; Humans; Male; Motor Activity; Osteoporotic Fractures; Physical Fitness; Vitamin B 12 | 2016 |
Effect of vitamin B-12 and n-3 polyunsaturated fatty acids on plasma homocysteine, ferritin, C-reaction protein, and other cardiovascular risk factors: a randomized controlled trial.
Topics: Adult; C-Reactive Protein; Cardiovascular Diseases; China; Dietary Supplements; Fatty Acids, Omega-3; Female; Ferritins; Fish Oils; Homocysteine; Humans; Male; Risk Factors; Vitamin B 12; Vitamin B Complex; Young Adult | 2015 |
Effects of 6-Month Folic Acid Supplementation on Cognitive Function and Blood Biomarkers in Mild Cognitive Impairment: A Randomized Controlled Trial in China.
Topics: Aged; Biomarkers; China; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Male; Treatment Outcome; Vitamin B 12 | 2016 |
The C677T MTHFR genotypes influence the efficacy of B9 and B12 vitamins supplementation to lowering plasma total homocysteine in hemodialysis.
Topics: Adult; Biomarkers; Dietary Supplements; Down-Regulation; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pharmacogenetics; Pharmacogenomic Variants; Phenotype; Renal Dialysis; Time Factors; Treatment Outcome; Tunisia; Vitamin B 12; Vitamins | 2016 |
Vitamin B-12 treatment of asymptomatic, deficient, elderly Chileans improves conductivity in myelinated peripheral nerves, but high serum folate impairs vitamin B-12 status response assessed by the combined indicator of vitamin B-12 status.
Topics: Aged; Chile; Dietary Supplements; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methylmalonic Acid; Nerve Fibers, Myelinated; Neural Conduction; Nutritional Status; Peripheral Nerves; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2016 |
Motor development related to duration of exclusive breastfeeding, B vitamin status and B12 supplementation in infants with a birth weight between 2000-3000 g, results from a randomized intervention trial.
Topics: Breast Feeding; Child Development; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Infant; Infant, Low Birth Weight; Male; Methylmalonic Acid; Motor Skills; Pyridoxal Phosphate; Riboflavin; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2015 |
Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine.
Topics: Adult; Aged; Alcohol Drinking; Atherosclerosis; Dietary Supplements; Folic Acid; Healthy Volunteers; Homocysteine; Humans; Linear Models; Male; Middle Aged; Sarcosine; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Wine | 2016 |
Effect of vitamin B12 and folic acid supplementation on biomarkers of endothelial function and inflammation among elderly individuals with hyperhomocysteinemia.
Topics: Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Biomarkers; Dietary Supplements; Double-Blind Method; Drug Combinations; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Inflammation Mediators; Male; Netherlands; Time Factors; Treatment Outcome; Vitamin B 12 | 2016 |
Phase II study of oral vitamin B12 supplementation as an alternative to intramuscular injection for patients with non-small cell lung cancer undergoing pemetrexed therapy.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Female; Folic Acid; Homocysteine; Humans; Lung Neoplasms; Male; Middle Aged; Pemetrexed; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2016 |
Reduced folate and serum vitamin metabolites in patients with rectal carcinoma: an open-label feasibility study of pemetrexed with folic acid and vitamin B12 supplementation.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cystathionine; Feasibility Studies; Female; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Intestinal Mucosa; Male; Methylmalonic Acid; Middle Aged; Neoadjuvant Therapy; Pemetrexed; Rectal Neoplasms; Rectum; Vitamin B 12 | 2016 |
Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study.
Topics: Adult; Aged; Anemia; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Vitamin B-12 concentration, memory performance, and hippocampal structure in patients with mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Apolipoprotein E4; Cognition; Cognitive Dysfunction; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Genotyping Techniques; Hippocampus; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Memory; Middle Aged; Polymorphism, Single Nucleotide; Verbal Learning; Vitamin B 12 | 2016 |
Effect of Vitamin B12 supplementation on serum homocysteine in patients undergoing hemodialysis: A randomized controlled trial.
Topics: Aged; Biomarkers; Dietary Supplements; Female; Hematocrit; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iran; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2016 |
Effects of maternal vitamin B12 supplementation on early infant neurocognitive outcomes: a randomized controlled clinical trial.
Topics: Adult; Brain; Child Development; Cognition; Dietary Supplements; Double-Blind Method; Female; Fetal Development; Homocysteine; Humans; India; Infant; Linear Models; Maternal Nutritional Physiological Phenomena; Micronutrients; Nutritional Status; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Socioeconomic Factors; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2017 |
Supplementation of vitamin B12 or folic acid on hemoglobin concentration in children 6-36 months of age: A randomized placebo controlled trial.
Topics: Anemia, Iron-Deficiency; Biomarkers; Child, Preschool; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Hemoglobins; Homocysteine; Humans; India; Infant; Infant Nutritional Physiological Phenomena; Iron, Dietary; Male; Prevalence; Receptors, Transferrin; Risk; Solubility; Urban Health; Vitamin B 12 | 2017 |
A randomized placebo controlled trial of vitamin B
Topics: Aged; Cholesterol; Cognitive Dysfunction; Creatinine; Diabetes Mellitus; Dietary Supplements; Female; Follow-Up Studies; Homocysteine; Humans; Male; Methylmalonic Acid; Neuropsychological Tests; Socioeconomic Factors; Triglycerides; Vitamin B 12 | 2017 |
Whey protein isolate improves vitamin B
Topics: Aged; Australia; Cross-Over Studies; Diet; Dietary Supplements; DNA Damage; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Nutrition Assessment; Vitamin B 12; Vitamin B 12 Deficiency; Whey Proteins | 2017 |
Folate and Vitamin B
Topics: Aged; Biomarkers; Body Mass Index; Brain; Cross-Sectional Studies; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Linear Models; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Nutritional Status; Organ Size; Tandem Mass Spectrometry; Transcobalamins; Vitamin B 12 | 2016 |
Effects of metformin versus placebo on vitamin B12 metabolism in non-diabetic breast cancer patients in CCTG MA.32.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Female; Homocysteine; Humans; Metformin; Methylmalonic Acid; Middle Aged; Treatment Outcome; Vitamin B 12 | 2017 |
Low vitamin B
Topics: Aged; alpha-Tocopherol; beta Carotene; Carcinoma, Squamous Cell; Case-Control Studies; Dietary Supplements; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Finland; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Prospective Studies; Riboflavin; Stomach Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 2017 |
Effects of folic acid combined with vitamin B12 on DVT in patients with homocysteine cerebral infarction.
Topics: Adult; Aged; Cerebral Infarction; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; International Normalized Ratio; Male; Middle Aged; Recurrence; Venous Thrombosis; Vitamin B 12 | 2017 |
Muscular contraction frequency does not affect plasma homocysteine concentration in response to energy expenditure- and intensity-matched acute exercise in sedentary males.
Topics: Adult; Anthropometry; Cross-Over Studies; Diet; Energy Metabolism; Exercise; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Muscle Contraction; Nutritional Status; Physical Endurance; Sedentary Behavior; Vitamin B 12; Vitamin B 6; Young Adult | 2018 |
Maternal methyl donor supplementation during gestation counteracts bisphenol A-induced oxidative stress in sows and offspring.
Topics: Actins; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Benzhydryl Compounds; Betaine; Catalase; Choline; Diet; Dietary Supplements; Female; Folic Acid; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Malondialdehyde; Maternal Nutritional Physiological Phenomena; Oxidative Stress; Phenols; Placenta; Pregnancy; Superoxide Dismutase; Swine; Vitamin B 12 | 2018 |
Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Calcium Carbonate; Cholecalciferol; CpG Islands; Dietary Supplements; DNA Methylation; Double-Blind Method; Epigenesis, Genetic; Female; Folic Acid; Germany; Homocysteine; Humans; Male; Middle Aged; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2018 |
Vitamin B12 and Homocysteine Levels Predict Different Outcomes in Early Parkinson's Disease.
Topics: alpha-Tocopherol; Antioxidants; Antiparkinson Agents; Cognition Disorders; Double-Blind Method; Female; Follow-Up Studies; Homocysteine; Humans; Male; Mental Status Schedule; Middle Aged; Parkinson Disease; Predictive Value of Tests; Selegiline; Treatment Outcome; Vitamin B 12 | 2018 |
Effect of Combined Treatment With Folic Acid, Vitamin B
Topics: Aged; Biomarkers; Cardiovascular Diseases; Double-Blind Method; Drug Combinations; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Inflammation; Inflammation Mediators; Middle Aged; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamins | 2018 |
Cobalamin and Folate Status among Breastfed Infants in Bhaktapur, Nepal.
Topics: Biomarkers; Breast Feeding; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant; Infant Nutritional Physiological Phenomena; Male; Methylmalonic Acid; Nepal; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Rehydration during exercise prevents the increase of homocysteine concentrations.
Topics: Adult; Creatine; Creatinine; Cross-Over Studies; Drinking Water; Exercise; Fluid Therapy; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Isotonic Solutions; Male; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12; Young Adult | 2019 |
Mecobalamin and early functional outcomes of ischemic stroke patients with H-type hypertension.
Topics: Aged; Aged, 80 and over; Brain Ischemia; Female; Homocysteine; Humans; Hypertension; Male; Middle Aged; Prognosis; Stroke; Treatment Outcome; Vitamin B 12 | 2018 |
The Effect of Whey and Soy Protein Isolates on Cognitive Function in Older Australians with Low Vitamin B
Topics: Aged; Australia; Cognition; Cross-Over Studies; Female; Folic Acid; Homocysteine; Humans; Male; Memory; Methylmalonic Acid; Middle Aged; Nutritional Status; Reaction Time; Sex Factors; Soybean Proteins; Vitamin B 12; Vitamin B 12 Deficiency; Whey Proteins | 2018 |
Effects of oral versus parenteral cobalamin supplementation on methylmalonic acid and homocysteine concentrations in dogs with chronic enteropathies and low cobalamin concentrations.
Topics: Administration, Oral; Animals; Dietary Supplements; Dog Diseases; Dogs; Female; Homocysteine; Infusions, Parenteral; Intestinal Diseases; Male; Methylmalonic Acid; Prospective Studies; Random Allocation; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Homocysteine, Thioretinaco Ozonide, and Oxidative Phosphorylation in Cancer and Aging: A Proposed Clinical Trial Protocol.
Topics: Adult; Aged; Aging; Drugs, Investigational; Homocysteine; Humans; Licensure; Middle Aged; Neoplasms; Oxidative Phosphorylation; Vitamin B 12 | 2019 |
Effect of folic acid supplementation on nerve conduction velocity in diabetic polyneuropathy patients.
Topics: Adult; Diabetic Neuropathies; Dietary Supplements; Double-Blind Method; Electromyography; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neural Conduction; Reaction Time; Severity of Illness Index; Statistics, Nonparametric; Vitamin B 12 | 2019 |
Potential of the multivitamin-mineral-trace element composition LaVita® before, during and after pregnancy.
Topics: Biomarkers; Dietary Supplements; Double-Blind Method; Female; Ferritins; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Iron; Male; Prospective Studies; Sex Factors; Time Factors; Vitamin B 12; Vitamin B 6; Zinc | 2019 |
A novel nutritional supplement to reduce plasma homocysteine in nonpregnant women: A randomised controlled trial in The Gambia.
Topics: Adolescent; Adult; Betaine; Dietary Supplements; Female; Folic Acid; Gambia; Homocysteine; Humans; Middle Aged; Nutritional Status; Riboflavin; Vitamin B 12; Young Adult | 2019 |
Maternal choline supplementation alters vitamin B-12 status in human and murine pregnancy.
Topics: Adult; Animals; Betaine-Homocysteine S-Methyltransferase; Choline; Choline Dehydrogenase; Dietary Supplements; Female; Gene Expression Regulation; Homeodomain Proteins; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methylmalonic Acid; Mice, Mutant Strains; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Trimester, Third; Transcription Factors; Vitamin B 12; Young Adult | 2019 |
Dietary intakes and biomarker patterns of folate, vitamin B
Topics: Aged; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Pyrophosphatases; Thioredoxin Reductase 1; Vitamin B 12; Vitamin B 6 | 2019 |
Vitamin B12 Status Upon Short-Term Intervention with a Vegan Diet-A Randomized Controlled Trial in Healthy Participants.
Topics: Adult; Biomarkers; Cardiovascular Diseases; Cholesterol; Diet, Vegan; Fatty Acids; Female; Healthy Volunteers; Homocysteine; Humans; Inflammation; Male; Methylmalonic Acid; Micronutrients; Nutritional Status; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
A randomized placebo-controlled trial of using B vitamins to prevent cognitive decline in older mild cognitive impairment patients.
Topics: Aged; Aged, 80 and over; Cognition; Cognitive Dysfunction; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2020 |
Infantile Tremor Syndrome or a Neurocutaneous Infantile B12 Deficiency (NIB) Syndrome?
Topics: Adolescent; Adult; Biomarkers; Child; Child, Preschool; Erythrocyte Indices; Female; Folic Acid; Homocysteine; Humans; India; Male; Malnutrition; Methylmalonic Acid; Mothers; Prospective Studies; Tremor; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2020 |
Vitamin B
Topics: Child; Child Development; Cognition; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; India; Intelligence Tests; Language Development; Male; Vitamin B 12; Vitamin B Complex | 2020 |
[Bioavailability of natural versus synthetic B vitamins and their effects on metabolic processes].
Topics: Biological Availability; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; Pilot Projects; Vitamin B 12; Vitamin B Complex; Vitamins | 2020 |
Association of antenatal vitamin B complex supplementation with neonatal vitamin B
Topics: China; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Pregnancy; Vitamin B 12; Vitamin B Complex | 2021 |
Effects of consuming red furu (fermented bean curd) on serum vitamin B-12, homocysteine and other cardiometabolic risk factors in young healthy volunteers: A randomized controlled trial.
Topics: Adult; Cardiometabolic Risk Factors; Coronary Artery Disease; Female; Healthy Volunteers; Homocysteine; Humans; Male; Phytotherapy; Soy Foods; Vitamin B 12; Young Adult | 2020 |
Long-term effects of folic acid and vitamin-B12 supplementation on fracture risk and cardiovascular disease: Extended follow-up of the B-PROOF trial.
Topics: Aged; Cardiovascular Diseases; Cerebrovascular Disorders; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Fractures, Bone; Homocysteine; Humans; Male; Odds Ratio; Osteoporotic Fractures; Placebos; Risk Factors; Vitamin B 12 | 2021 |
Multiple Micronutrients, Lutein, and Docosahexaenoic Acid Supplementation during Lactation: A Randomized Controlled Trial.
Topics: Adult; beta Carotene; Breast Feeding; Dietary Supplements; Docosahexaenoic Acids; Double-Blind Method; Eicosapentaenoic Acid; Female; Germany; Homocysteine; Humans; Infant; Lactation; Lutein; Maternal Nutritional Physiological Phenomena; Micronutrients; Milk, Human; Vitamin B 12; Vitamin D | 2020 |
Effects of vitamin B12, folate, and entacapone on homocysteine levels in levodopa-treated Parkinson's disease patients: A randomized controlled study.
Topics: Aged; Antiparkinson Agents; Catechols; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Research Design; Vitamin B 12 | 2021 |
Parkinson's disease: Research puts spotlight on thiamine deficiency and cardiovascular health.
Topics: Folic Acid; Homocysteine; Humans; Levodopa; Parkinson Disease; Thiamine Deficiency; Vitamin B 12 | 2021 |
Cobalamin and folate status in women during early pregnancy in Bhaktapur, Nepal.
Topics: Female; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Nepal; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
Plasma Methylmalonic Acid Concentration in Folic Acid-Supplemented Depressed Patients with Low or Marginal Vitamin B-12: A Randomized Trial.
Topics: Aged; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Vitamin B 12; Vitamins | 2021 |
Effect of zinc supplementation on circulating concentrations of homocysteine, vitamin B
Topics: Adult; Aged; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Postmenopause; Vitamin B 12; Vitamins; Zinc | 2022 |
Adolescent Afghan Refugees Display a High Prevalence of Hyperhomocysteinemia and Associated Micronutrients Deficiencies Indicating an Enhanced Risk of Cardiovascular Disease in Later Life.
Topics: Adolescent; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Malnutrition; Micronutrients; Prevalence; Refugees; Vitamin B 12 | 2022 |
DHA status influences effects of B-vitamin supplementation on cognitive ageing: a post-hoc analysis of the B-proof trial.
Topics: Aged; Cognition; Cognitive Aging; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Folic Acid; Homocysteine; Humans; Vitamin B 12; Vitamin B Complex | 2022 |
The effects of vitamin B12 supplementation on metabolic profile of patients with non-alcoholic fatty liver disease: a randomized controlled trial.
Topics: Blood Glucose; Dietary Supplements; Double-Blind Method; Homocysteine; Humans; Metabolome; Non-alcoholic Fatty Liver Disease; Vitamin B 12 | 2022 |
B Vitamin Supplementation Slows Cognitive Decline in Mild Cognitive Impairment Patients with Frontal Lobe Atrophy.
Topics: Aspirin; Atrophy; Cognition; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Frontal Lobe; Homocysteine; Humans; Vitamin B 12; Vitamin B Complex | 2022 |
Homocysteine thiolactone contributes to the prognostic value of fibrin clot structure/function in coronary artery disease.
Topics: Coronary Artery Disease; Fibrin; Folic Acid; Homocysteine; Humans; Myocardial Infarction; Prognosis; Risk Factors; Thrombosis; Vitamin B 12; Vitamin B Complex | 2022 |
Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial.
Topics: Adolescent; Adult; Aged; Betaine; Dietary Supplements; Double-Blind Method; East Asian People; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Vitamin B 12; Vitamin B Complex; Young Adult | 2023 |
Daily Folic Acid and/or Vitamin B12 Supplementation Between 6 and 30 Months of Age and Cardiometabolic Risk Markers After 6-7 Years: A Follow-Up of a Randomized Controlled Trial.
Topics: Adiponectin; Child; Child, Preschool; Dietary Supplements; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Leptin; Vitamin B 12 | 2023 |
2009 other study(ies) available for homocysteine and vitamin b 12
| Article | Year |
|---|---|
Vitamin B12--folate interrelations.
Topics: Anemia, Megaloblastic; DNA; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Glycine; Homocysteine; Humans; Methionine; Methylmalonyl-CoA Mutase; Nervous System Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 1976 |
5-methyltetrahydrofolate: synthesis and utilization in normal and SV40-transformed BHK-21 cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cricetinae; Folic Acid; Homocysteine; Kidney; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Simian virus 40; Tetrahydrofolates; Vitamin B 12 | 1977 |
N5-Methyltetrahydrofolate-homocysteine cobalamin methyltransferase activity in chronic erythremic myelosis (Di Guglielmo syndrome).
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Pernicious; Apoenzymes; Bone Marrow; Homocysteine; Humans; Leukemia, Erythroblastic, Acute; Methyltransferases; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1977 |
De novo synthesis of methionine in normal and Brugia-infected Aedes aegypti.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aedes; Animals; Brugia; Cell-Free System; Female; Filarioidea; Homocysteine; Male; Methionine; Molecular Weight; S-Adenosylmethionine; Tetrahydrofolates; Tissue Extracts; Vitamin B 12 | 1979 |
[Vitamin B 12 dependent methionine biosynthesis in pseudomonas aeruginosa].
Topics: Cysteine; Homocysteine; Methionine; Methylnitronitrosoguanidine; Mutagens; Pseudomonas aeruginosa; Stereoisomerism; Vitamin B 12 | 1975 |
Folate-responsive homocystinuria and "schizophrenia". A defect in methylation due to deficient 5,10-methylenetetrahydrofolate reductase activity.
Topics: Adolescent; Alcohol Oxidoreductases; Diagnosis, Differential; Female; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Methionine; Methylation; Schizophrenia; Tetrahydrofolates; Vitamin B 12 | 1975 |
Formation of methyl mercury by bacteria.
Topics: Bacillus; Bacteria; Enterobacter; Escherichia; Homocysteine; Mercury; Methylation; Oxygen; R Factors; Soil Microbiology; Staphylococcus; Stereoisomerism; Streptococcus; Vitamin B 12; Water Microbiology | 1975 |
Folate-dependent enzymes in cultured Chinese hamster ovary cells: induction of 5-methyltetrahydrofolate homocysteine cobalamin methyltransferase by folate and methionine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Division; Cell Line; Culture Media; Cycloheximide; Enzyme Induction; Folic Acid; Homocysteine; Kinetics; Methionine; Methyltransferases; Thymidylate Synthase; Time Factors; Vitamin B 12 | 1975 |
The anti-folate effect of methionine on bone marrow of normal and vitamin B12 deficient rats.
Topics: Animals; Bone Marrow; Deoxyuridine; DNA; Folic Acid; Folic Acid Antagonists; Homocysteine; Liver; Male; Methionine; Methionine Adenosyltransferase; Rats; Thymidine; Vitamin B 12; Vitamin B 12 Deficiency | 1975 |
Effect of vitamin B12 and folate on biosynthesis of methionine from homocysteine in the nematode Caenorhabditis briggsae.
Topics: Animals; Choline; Folic Acid; Homocysteine; Methionine; Nematoda; Vitamin B 12 | 1976 |
Prevalence of vitamin B12 deficiency among geriatric outpatients.
Topics: Aged; Aged, 80 and over; Female; Gastritis, Atrophic; Homocysteine; Humans; Male; Methylmalonic Acid; New York; Outpatients; Peripheral Nervous System Diseases; Prevalence; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 1992 |
Comparison of cobalamin-independent and cobalamin-dependent methionine synthases from Escherichia coli: two solutions to the same chemical problem.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alkylation; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cysteine; Escherichia coli; Homocysteine; Iodoacetamide; Methionine; Molecular Sequence Data; Recombinant Proteins; Restriction Mapping; Tetrahydrofolates; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone; Trypsin; Vitamin B 12 | 1992 |
Effect of the synthetic N-homocysteine thiolactonyl derivatives, thioretinaco, thioretinamide, and thioco on growth and lactate production by malignant cells.
Topics: Antineoplastic Agents; Cell Division; Cells, Cultured; Fibroblasts; Homocysteine; Humans; Lactates; Lactic Acid; Tretinoin; Tumor Cells, Cultured; Vitamin B 12 | 1992 |
Plasma homocysteine in women on oral oestrogen-containing contraceptives and in men with oestrogen-treated prostatic carcinoma.
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Contraceptives, Oral, Hormonal; Estradiol Congeners; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Prostatic Neoplasms; Risk Factors; Vitamin B 12 | 1992 |
High prevalence of cobalamin deficiency in elderly outpatients.
Topics: Aged; Aged, 80 and over; Ambulatory Care; Colorado; Female; Homocysteine; Humans; Male; Mass Screening; Methylmalonic Acid; Neurologic Examination; Neuropsychological Tests; Prevalence; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 1992 |
Methionine auxotrophy in inborn errors of cobalamin metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Division; Cell Line; Cobamides; Fibroblasts; Homocysteine; Humans; Metabolism, Inborn Errors; Methionine; Vitamin B 12; Vitamin B 12 Deficiency | 1992 |
Plasma homocysteine before and after methionine loading with regard to age, gender, and menopausal status.
Topics: Adult; Aged; Aging; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Menopause; Methionine; Middle Aged; Pyridoxal Phosphate; Sex Characteristics; Vascular Diseases; Vitamin B 12 | 1992 |
Hyperhomocysteinaemia in stroke: prevalence, cause, and relationships to type of stroke and stroke risk factors.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cerebrovascular Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Pyridoxal Phosphate; Risk Factors; Vitamin B 12 | 1992 |
Inhibition of cobalamin-dependent enzymes by cobalamin analogues in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Folic Acid; Homocysteine; Male; Methionine; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Nitrous Oxide; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Succinates; Succinic Acid; Vitamin B 12 | 1991 |
Changes in cobalamin metabolism are associated with the altered methionine auxotrophy of highly growth autonomous human melanoma cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Division; Homocysteine; Humans; Melanoma; Methionine; Phenotype; Tetrahydrofolates; Tumor Cells, Cultured; Vitamin B 12 | 1991 |
Plasma homocysteine in venous thromboembolism.
Topics: Adult; Creatinine; Cystathionine beta-Synthase; Fasting; Female; Folic Acid; Genetic Carrier Screening; Genotype; Homocysteine; Homocystinuria; Humans; Male; Methionine; Thromboembolism; Vitamin B 12 | 1991 |
Homocysteine content of plasma in ischemic heart disease, the reducing effect of pyridoxine, folate, cobalamin, choline, riboflavin and troxerutin. Correction of a calculation error.
Topics: Amino Acids; Anticoagulants; Choline; Coronary Disease; Folic Acid; Homocysteine; Humans; Hydroxyethylrutoside; Pyridoxine; Riboflavin; Vitamin B 12 | 1991 |
Intermediate hyperhomocysteinemia resulting from compound heterozygosity of methylenetetrahydrofolate reductase mutations.
Topics: Adolescent; Adult; Alleles; Amino Acid Metabolism, Inborn Errors; Enzyme Activation; Female; Folic Acid; Heterozygote; Homocysteine; Hot Temperature; Humans; Infant, Newborn; Lymphocytes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pedigree; Substrate Specificity; Vitamin B 12 | 1991 |
Monitoring cobalamin inactivation during nitrous oxide anesthesia by determination of homocysteine and folate in plasma and urine.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Anesthesia, Intravenous; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Nitrous Oxide; Postoperative Period; Vitamin B 12 | 1991 |
Maternal vegan diet causing a serious infantile neurological disorder due to vitamin B12 deficiency.
Topics: Adult; Breast Feeding; Diet, Vegetarian; Female; Homocysteine; Humans; Infant; Methionine; Methylmalonic Acid; Milk, Human; Nervous System Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 1991 |
Homocysteine and lipid metabolism in atherogenesis: effect of the homocysteine thiolactonyl derivatives, thioretinaco and thioretinamide.
Topics: Animals; Arteriosclerosis; Diet, Atherogenic; Homocysteine; Lipids; Muscle, Smooth, Vascular; Rabbits; Tretinoin; Vitamin B 12 | 1990 |
Diagnosis of cobalamin deficiency: II. Relative sensitivities of serum cobalamin, methylmalonic acid, and total homocysteine concentrations.
Topics: Adult; Aged; Celiac Disease; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Intestines; Male; Methylmalonic Acid; Middle Aged; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 1990 |
Clinical spectrum and diagnosis of cobalamin deficiency.
Topics: Bilirubin; Female; Folic Acid; Gastrins; Hematocrit; Homocysteine; Humans; L-Lactate Dehydrogenase; Male; Methylmalonic Acid; Prospective Studies; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 1990 |
Inhibition of neoplastic growth by N-homocysteine thiolactonyl retinamido cobalamin.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Homocysteine; Humans; Male; Mice; Mice, Nude; Neoplasms, Experimental; Pancreatic Neoplasms; Tumor Cells, Cultured; Vitamin B 12 | 1989 |
Role of homocysteine in metR-mediated activation of the metE and metH genes in Salmonella typhimurium and Escherichia coli.
Topics: Escherichia coli; Gene Expression Regulation; Genes, Bacterial; Homocysteine; Methionine; Methyltransferases; Salmonella typhimurium; Transcription, Genetic; Vitamin B 12 | 1989 |
Chemopreventive effect of N-homocysteine thiolactonyl retinamido cobalamin on carcinogenesis by ethyl carbamate in mice.
Topics: Animals; Antineoplastic Agents; Homocysteine; Mice; Neoplasms, Experimental; Spectrophotometry, Ultraviolet; Spectrum Analysis; Tretinoin; Urethane; Vitamin B 12 | 1989 |
Altered methionine metabolism in metastatic variants of a human melanoma cell line.
Topics: Cell Division; Culture Media; Homocysteine; Humans; Melanoma; Methionine; Neoplasm Metastasis; S-Adenosylmethionine; Tumor Cells, Cultured; Vitamin B 12 | 1989 |
Reduction of plasma lipid and homocysteine levels by pyridoxine, folate, cobalamin, choline, riboflavin, and troxerutin in atherosclerosis.
Topics: Adult; Anticoagulants; Choline; Coronary Artery Disease; Coronary Disease; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hydroxyethylrutoside; Lipids; Male; Middle Aged; Pyridoxine; Riboflavin; Vitamin B 12 | 1989 |
Cobalamin inactivation decreases purine and methionine synthesis in cultured human lymphoblasts.
Topics: Folic Acid; Homocysteine; Humans; Lymphocytes; Methionine; Nitrous Oxide; Oxidation-Reduction; Purines; Serine; Vitamin B 12 | 1986 |
Regulation of the metR gene of Salmonella typhimurium.
Topics: beta-Galactosidase; Cloning, Molecular; DNA, Recombinant; Gene Expression Regulation; Genes, Bacterial; Genes, Regulator; Homocysteine; Lysogeny; Methionine; Mutation; Salmonella typhimurium; Vitamin B 12 | 1987 |
The total serum homocysteine as an indicator of vitamin B12 and folate status.
Topics: Adenosine; Adenosylhomocysteinase; Adult; Aged; Carbon Radioisotopes; Female; Folic Acid; Homocysteine; Humans; Hydrolases; Infant; Male; Middle Aged; Reference Standards; Tritium; Vitamin B 12 | 1988 |
Methylation deficiency causes vitamin B12-associated neuropathy in the pig.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Homocysteine; Methylation; Nervous System Diseases; Nitrous Oxide; S-Adenosylhomocysteine; S-Adenosylmethionine; Spinal Cord; Swine; Vitamin B 12 | 1988 |
The role of transcobalamin II in the methionine dependency of human lymphocytes.
Topics: Cells, Cultured; Homocysteine; Humans; Lymphocyte Activation; Lymphocytes; Methionine; Transcobalamins; Vitamin B 12 | 1988 |
Higher total plasma homocysteine in vitamin B12 deficiency than in heterozygosity for homocystinuria due to cystathionine beta-synthase deficiency.
Topics: Cystathionine beta-Synthase; Heterozygote; Homocysteine; Homocystinuria; Humans; Hydro-Lyases; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 1988 |
Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis.
Topics: Adolescent; Adult; Aged; Anemia; Anemia, Megaloblastic; Ataxia; Erythrocyte Indices; Erythrocytes; Female; Hematocrit; Homocysteine; Humans; Hypesthesia; Iron; Male; Methylmalonic Acid; Middle Aged; Nervous System Diseases; Neurocognitive Disorders; Paresthesia; Vitamin B 12; Vitamin B 12 Deficiency | 1988 |
Folic acid--an innocuous means to reduce plasma homocysteine.
Topics: Adult; Amino Acids; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Pyridoxine; Vitamin B 12 | 1988 |
Vitamin B12 responsive homocystinuria and megaloblastic anemia: heterogeneity in methylcobalamin deficiency.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Cells, Cultured; Fibroblasts; Homocysteine; Homocystinuria; Humans; Infant; Male; Methionine; Vitamin B 12; Vitamin B 12 Deficiency | 1987 |
Cisplatin neurotoxicity: failure to demonstrate vitamin B12 inactivation.
Topics: Analysis of Variance; Circadian Rhythm; Cisplatin; Cobamides; Female; Homocysteine; Humans; Infusions, Parenteral; Methylmalonic Acid; Ovarian Neoplasms; Urinary Bladder Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 1985 |
Folic acid metabolism in vitamin B12-deficient sheep. Effects of injected methionine on methotrexate transport and the activity of enzymes associated with folate metabolism in liver.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Female; Folic Acid; Homocysteine; Liver; Membranes; Methionine; Methotrexate; Methyltransferases; NAD; NADP; S-Adenosylmethionine; Serum Albumin, Bovine; Sheep; Tetrahydrofolate Dehydrogenase; Tritium; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Correlation between the level of vitamin-B12-dependent methionine synthetase and intracellular concentration of vitamin B12 in some bacteria.
Topics: Apoenzymes; Bacterial Proteins; Carbon Radioisotopes; Chloramphenicol; Chromatium; Cobalt; Escherichia coli; Homocysteine; Methionine; Methyltransferases; Rhodospirillum rubrum; Streptomyces; Tetracycline; Tetrahydrofolates; Vitamin B 12 | 1974 |
Methionine biosynthesis in Ochromonas malhamensis.
Topics: Adenosine Triphosphate; Alcohols; Carbon Isotopes; Cyanides; Enzyme Activation; Eukaryota; Flavin Mononucleotide; Folic Acid; Homocysteine; Kinetics; Light; Magnesium; Methionine; NAD; Oxygen; Sulfur; Transferases; Vitamin B 12 | 1969 |
Formation of the N5-methyltetrahydrofolate-homocysteine methyltransferase holoenzyme from apoenzyme and adenosyl-B 12.
Topics: Adenine Nucleotides; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Enzyme Precursors; Escherichia coli; Folic Acid; Homocysteine; Methionine; NAD; Transferases; Vitamin B 12 | 1970 |
Vitamin B12-dependent methionine synthesis in Rhizobium meliloti.
Topics: Carbon Radioisotopes; Cell-Free System; Chromatography, Ion Exchange; Dithiothreitol; Flavin Mononucleotide; Homocysteine; Kinetics; Magnesium; Methionine; Methyltransferases; Oxidation-Reduction; Rhizobium; S-Adenosylmethionine; Tetrahydrofolates; Time Factors; Vitamin B 12 | 1974 |
The effect of DL-methionine, vitamin B 12, and thyroid powder on metabolism of formiminoglutamic acid in rats.
Topics: Animals; Azo Compounds; Body Weight; Diet; FIGLU Test; Folic Acid; Folic Acid Deficiency; Glutarates; Growth; Homocysteine; Liver; Male; Methionine; Methods; Rats; Tetrahydrofolates; Thyroid (USP); Thyroid Hormones; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
5-methyltetrahydrofolate homocysteine cobalamin methyltransferase in human bone marrow and its relationship to pernicious anemia.
Topics: Anemia, Pernicious; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Cell-Free System; Chromatography, Ion Exchange; Erythrocytes; Homocysteine; Humans; Kinetics; Methyltransferases; S-Adenosylmethionine; Tetrahydrofolates; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Regulation of 5-methyltetrahydrofolate: homocysteine methyltransferase activity by methionine, vitamin B12, and folate in cultured baby hamster kidney cells.
Topics: Animals; Cells, Cultured; Cricetinae; Folic Acid; Homocysteine; Kidney; Mercaptoethanol; Methionine; Methyltransferases; Puromycin; Tetrahydrofolates; Vitamin B 12 | 1973 |
Regulation of homocysteine biosynthesis in Salmonella typhimurium.
Topics: Acyltransferases; Bacteriological Techniques; Carbon Isotopes; Enzyme Repression; Feedback; Genetics, Microbial; Homocysteine; Homoserine; Hydro-Lyases; L-Serine Dehydratase; Lyases; Methionine; Molecular Biology; Mutation; S-Adenosylmethionine; Salmonella typhimurium; Spectrophotometry; Succinates; Tetrahydrofolates; Tritium; Vitamin B 12 | 1972 |
Methionine and vitamin B 12 repression and precursor induction in the regulation of homocysteine methylation in Salmonella typhimurium.
Topics: Apoproteins; Chloramphenicol; Enzyme Induction; Enzyme Precursors; Genes, Regulator; Homocysteine; Methionine; Methylation; Methyltransferases; Mutation; Oxidoreductases; Salmonella typhimurium; Tetrahydrofolates; Vitamin B 12 | 1973 |
Relationship between the cobalamin-dependent methyltransferase activities in Escherichia coli B and an E. coli B (Met H - ) mutant.
Topics: Apoproteins; Binding Sites; Carbon Isotopes; Chloromercuribenzoates; Chromatography, Gel; Cobamides; Drug Stability; Enzyme Repression; Escherichia coli; Genetics, Microbial; Homocysteine; Methionine; Methyltransferases; Mutation; Protein Binding; Temperature; Tetrahydrofolates; Tritium; Urea; Vitamin B 12 | 1973 |
Transport of vitamin B12 in Escherichia coli: genetic studies.
Topics: Binding Sites; Biological Transport, Active; Cell Membrane; Cell Wall; Cell-Free System; Chromosome Mapping; Cobalt Isotopes; Colicins; Conjugation, Genetic; Drug Resistance, Microbial; Escherichia coli; Genes; Homocysteine; Methionine; Methyltransferases; Mutation; Receptors, Drug; Recombination, Genetic; Transduction, Genetic; Vitamin B 12 | 1973 |
Effect of methionine and vitamin B-12 on the activities of methionine biosynthetic enzymes in metJ mutants of Escherichia coli K12.
Topics: Adenosine Triphosphate; Culture Media; Cystathionine; Enzyme Repression; Escherichia coli; Folic Acid; Homocysteine; Hydro-Lyases; L-Serine Dehydratase; Methionine; Methyltransferases; Mutation; Oxidoreductases; S-Adenosylmethionine; Time Factors; Transferases; Vitamin B 12 | 1973 |
On the cation sensibility of the vitamin B12-dependent methionine synthetase (5-methyltetrahydrofolate-homocysteine-methyltransferase from Escherichia coli).
Topics: Ammonia; Barium; Calcium; Cations, Divalent; Cations, Monovalent; Chromatography, Gel; Escherichia coli; Homocysteine; Lithium; Magnesium; Manganese; Methyltransferases; Potassium; Quaternary Ammonium Compounds; Sodium; Spectrophotometry, Ultraviolet; Strontium; Tetrahydrofolates; Threonine; Vitamin B 12 | 1973 |
The involvement of methionine regulatory mutants in the suppresion of b12-dependent homocysteine transmethylase (metH) mutants of Salmonella typhimurium.
Topics: Drug Resistance, Microbial; Ethionine; Genes, Regulator; Homocysteine; Methionine; Methyltransferases; Mutation; Salmonella typhimurium; Suppression, Genetic; Transduction, Genetic; Vitamin B 12 | 1974 |
Folic acid and the methylation of homocysteine by Bacillus subtilis.
Topics: Alcohol Oxidoreductases; Bacillus subtilis; Chromatography, Gel; Chromatography, Thin Layer; Cobamides; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Serine; Ultrasonics; Vitamin B 12 | 1972 |
Hereditary transcobalamin II deficiency: the role of transcobalamin II in vitamin B 12 -mediated reactions.
Topics: Amino Acid Metabolism, Inborn Errors; Cystathionine; DNA; Hematopoietic System; Homocysteine; Humans; Infant; Infant, Newborn; Isomerases; Leukocytes; Malonates; Methionine; Methyltransferases; Oxidation-Reduction; Propionates; Succinates; Vitamin B 12; Vitamin B 12 Deficiency | 1972 |
Betaine-homocysteine transmethylase in Pseudomonas denitrificans, a vitamin B 12 overproducer.
Topics: Betaine; Biological Assay; Cell-Free System; Chromatography, Paper; Culture Media; Enzyme Repression; Homocysteine; Hydrogen-Ion Concentration; Lactobacillus; Methionine; Methyltransferases; Mutation; Pantothenic Acid; Pseudomonas; Temperature; Vitamin B 12 | 1973 |
Effect of methionine on specific folate coenzyme pools in vitamin B 12 deficient and supplemented rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Carbon Isotopes; Chromatography, DEAE-Cellulose; Coenzymes; FIGLU Test; Folic Acid; Glutamates; Homocysteine; Liver; Male; Malonates; Methionine; Methyltransferases; Oligopeptides; Rats; Tetrahydrofolates; Tritium; Vitamin B 12; Vitamin B 12 Deficiency | 1973 |
[Importance and regulation of the cobalamin-dependent methionine synthetase and the betaine: homocystein methyltransferase in methionine and tetrahydrofolic acid metabolism of the rat].
Topics: Animals; Betaine; Coenzyme A; Diet; Female; Folic Acid; Homocysteine; Kidney; Liver; Methionine; Methylation; Methyltransferases; Rats; Tetrahydrofolates; Vitamin B 12 | 1973 |
Histidine catabolism in iron-deficient rats.
Topics: Anemia, Hypochromic; Animals; Blood Proteins; FIGLU Test; Hemoglobins; Histidine; Homocysteine; Iron; Liver; Male; Methylation; Rats; Transferases; Vitamin B 12 | 1973 |
Mental retardation, megaloblastic anaemia, methylmalonic aciduria and abnormal homocysteine metabolism due to an error in vitamin B12 metabolism.
Topics: Amino Acid Isomerases; Amino Acids; Anemia, Macrocytic; Autopsy; Brain; Brain Chemistry; Cells, Cultured; Child; Culture Media; Fibroblasts; Homocysteine; Humans; Intellectual Disability; Liver; Lung; Lyases; Malonates; Metabolism, Inborn Errors; Methionine; Spleen; Vitamin B 12 | 1974 |
Enzymic synthesis of methionine: formation of a radioactive cobamide enzyme with N5-methyl-14C-tetrahydrofolate.
Topics: Carbon Isotopes; Catalysis; Chromatography, Gel; Escherichia coli; Folic Acid; Homocysteine; Kinetics; Methionine; Methylation; Transferases; Vitamin B 12 | 1967 |
Escherichia coli B N5-methyltetrahydrofolate-homocysteine vitamin-B12 transmethylase: formation and photolability of a methylcobalamin enzyme.
Topics: Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Chromatography, Paper; Drug Stability; Electrophoresis; Escherichia coli; Folic Acid; Homocysteine; Hydrogen-Ion Concentration; Light; Models, Biological; Oxidation-Reduction; Paper; Spectrophotometry; Transferases; Vitamin B 12 | 1968 |
Chemical propylation of vitamin-B12 transmethylase: anomalous behavior of S-adenosyl-L-methionine.
Topics: Adenine Nucleotides; Alkylation; Carbon Isotopes; Escherichia coli; Flavins; Folic Acid; Homocysteine; Methionine; Models, Chemical; Serum Albumin, Bovine; Sulfhydryl Compounds; Transferases; Vitamin B 12 | 1968 |
Studies on the nature of the bound cobamide in E. coli N5-methyltetrahydrofolate-homocysteine transmethylase.
Topics: Carbon Isotopes; Chloromercuribenzoates; Escherichia coli; Fluorometry; Homocysteine; Radioisotopes; Transferases; Vitamin B 12 | 1968 |
Escherichia coli B N5-methyltetrahydrofolate-homocysteine methyltransferase: sequential formation of bound methylcobalamin with S-adenosyl-L-methionine and N5-methyltetrahydrofolate.
Topics: Carbon Isotopes; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Escherichia coli; Folic Acid; Homocysteine; Light; Methionine; Methylation; Nucleosides; Temperature; Time Factors; Transferases; Vitamin B 12 | 1969 |
Escherichia coli B N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase: activation with S-adenosyl-L-methionine and the mechanism for methyl group transfer.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Models, Biological; Nucleosides; Time Factors; Transferases; Vitamin B 12 | 1969 |
Genetic transformation in Escherichia coli.
Topics: DNA; Escherichia coli; Genetics, Microbial; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methionine; Temperature; Transformation, Genetic; Vitamin B 12 | 1969 |
On the role of S-adenoxylmethionine in the vitamin B12 dependent methionine biosynthesis.
Topics: Alcohols; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Escherichia coli; Flavin Mononucleotide; Folic Acid; Homocysteine; Hydroxyapatites; Kinetics; Methionine; Methods; Methylation; Nucleosides; Spectrophotometry; Sulfur; Transferases; Vitamin B 12 | 1969 |
Escherichia coli B 5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase: catalysis by a reconstituted methyl-14C-cobalamin holoenzyme and the function of S-adenosyl-l-methionine.
Topics: Carbon Isotopes; Escherichia coli; Flavin Mononucleotide; Folic Acid; Homocysteine; Hydrogen; Kinetics; Methionine; Nucleosides; Oxygen; Protein Binding; Transferases; Vitamin B 12 | 1970 |
Escherichia coli B 5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase: resolution and reconstitution of holoenzyme.
Topics: Alcohols; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Gel; Darkness; Escherichia coli; Homocysteine; Light; Methionine; Methylation; Nucleosides; Protein Binding; Spectrophotometry; Sulfhydryl Compounds; Sulfur; Tetroses; Transferases; Tritium; Ultracentrifugation; Urea; Vibration; Vitamin B 12 | 1970 |
Spectrophotometric evidence for the formation of an Escherichia coli B B-12s methyltransferase.
Topics: Alcohols; Carbon Isotopes; Escherichia coli; Folic Acid; Free Radicals; Homocysteine; Hydrogen-Ion Concentration; Iodides; Ligases; Methionine; Methylation; Oxidation-Reduction; Spectrophotometry; Sulfur; Transferases; Ultraviolet Rays; Vitamin B 12 | 1970 |
Methylation of mercury compounds by methylcobalamin.
Topics: Chemical Phenomena; Chemistry; Chlorides; Chromatography, Gas; Escherichia coli; Homocysteine; Hydroxides; Hydroxocobalamin; Kinetics; Mercaptoethanol; Mercury; Mercury Poisoning; Methylation; Organometallic Compounds; Spectrophotometry; Ultraviolet Rays; Vitamin B 12 | 1971 |
The vitamin B12-dependent methionine synthetase. The cycle of transmethylation.
Topics: Enzyme Induction; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Methyltransferases; Nucleosides; Oxidation-Reduction; Spectrophotometry; Transferases; Vitamin B 12 | 1971 |
Methylcobalamin as a substrate at a separate site on Escherichia coli B N 5 -methyltetrahydrofolate-homocysteine cobalamin methyltransferase.
Topics: Alkylation; Binding Sites; Carbon Isotopes; Catalysis; Coenzymes; Electrophoresis; Electrophoresis, Disc; Escherichia coli; Folic Acid; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methylation; Methyltransferases; Temperature; Tritium; Urea; Vitamin B 12 | 1971 |
Vitamin B 12 and methionine synthesis in Escherichia coli.
Topics: Acyltransferases; Aerobiosis; Alcohol Oxidoreductases; Anilides; Carbon Isotopes; Chromatography, Ion Exchange; Enzyme Repression; Escherichia coli; Flavin-Adenine Dinucleotide; Folic Acid; Genetics, Microbial; Homocysteine; Homoserine; Kinetics; Methionine; Methyltransferases; Mutation; Serine; Succinates; Transferases; Vitamin B 12 | 1971 |
Escherichia coli B N 5 -methyltetrahydrofolate-homocysteine cobalamin methyltransferase: gel-filtration behavior of apoenzyme and holoenzymes.
Topics: Alkylation; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Dithiothreitol; Drug Stability; Escherichia coli; Folic Acid; Homocysteine; Hydroxocobalamin; Macromolecular Substances; Mathematics; Methylation; Methyltransferases; Molecular Weight; Tritium; Urea; Vitamin B 12 | 1971 |
Nutrition and vitamin B12 metabolism of a soil bacterium.
Topics: Amines; Animals; Arthrobacter; Bacteria; Biological Assay; Culture Media; Edetic Acid; Escherichia coli; Homocysteine; Humans; Liver; Methionine; Oxygen Consumption; Rabbits; Rats; Soil Microbiology; Thiamine; Vitamin B 12 | 1968 |
Transductional analysis of Pseudomonas aeruginosa methionineless auxotrophs.
Topics: Cysteine; Genetics, Microbial; Homocysteine; Methionine; Methylation; Mutation; Pseudomonas aeruginosa; Transduction, Genetic; Vitamin B 12 | 1969 |
[Clinical trial of a new hepatoprotective preparation].
Topics: Alcoholism; Cholelithiasis; Choline; Diabetes Complications; Drug Combinations; Homocysteine; Humans; Lactones; Liver Diseases; Phosphoric Acids; Vitamin B 12 | 1972 |
Homocystinuria associated with decreased methylenetetrahydrofolate reductase activity.
Topics: Adolescent; Carbon Isotopes; Coenzymes; Female; Fibroblasts; Folic Acid; Homocysteine; Homocystinuria; Humans; L-Serine Dehydratase; Male; Methionine; Methylation; Methyltransferases; Oxidoreductases; Vitamin B 12 | 1972 |
Combined vitamin responsiveness in homocystinuria.
Topics: Adolescent; Adult; Amino Acids; Child; Drug Synergism; Female; Folic Acid; Folic Acid Deficiency; Glycine; Homocysteine; Homocystinuria; Humans; L-Serine Dehydratase; Male; Metabolic Diseases; Methionine; Methylation; Pyridoxine; Vitamin B 12 | 1972 |
Isolation of a cobalamin containing 5-methyltetrahydrofolate-homocysteine transmethylase from mammalian kidney.
Topics: Ammonium Sulfate; Animals; Calcium Phosphates; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Drug Stability; Flavin-Adenine Dinucleotide; Folic Acid; Homocysteine; Kidney; Methods; Methyltransferases; Protamines; S-Adenosylmethionine; Spectrophotometry; Sulfuric Acids; Swine; Ultraviolet Rays; Vitamin B 12 | 1971 |
[Hereditary deficiencies of B 12 coenzymes].
Topics: Coenzymes; Female; Homocysteine; Humans; Infant; Isomerases; Male; Metabolism, Inborn Errors; Methionine; Methyltransferases; Vitamin B 12; Vitamin B 12 Deficiency | 1971 |
Defective metabolism of vitamin B 12 in fibroblasts from children with methylmalonicaciduria.
Topics: Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Cobalt Isotopes; Deoxyadenosines; Enzyme Activation; Fibroblasts; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Male; Malonates; Metabolism, Inborn Errors; Methylation; Methyltransferases; Vitamin B 12 | 1971 |
Two enzymic mechanisms for the methylation of homocysteine by extracts of Escherichia coli.
Topics: Alkylation; Enzymes; Escherichia coli; Homocysteine; In Vitro Techniques; Methionine; Molecular Biology; Mutation; Transferases; Ultrasonics; Vitamin B 12 | 1964 |
Methionine synthesis by extracts of Salmonella typhimurium.
Topics: Alcohol Oxidoreductases; Alkylation; Homocysteine; In Vitro Techniques; Methionine; Molecular Biology; Salmonella typhimurium; Serine; Vitamin B 12 | 1966 |
Interrelationship of adenosyl methionine and methyl-B12 in the biosynthesis of methionine.
Topics: Animals; Cattle; Coenzymes; Escherichia coli; Homocysteine; Ligases; Liver; Methionine; Nucleosides; Spectrophotometry; Swine; Vitamin B 12 | 1966 |
N5-methyltetrahydrofolate-homocysteine transmethylase. Partial purification and properties.
Topics: Alkylation; Chromatography; Escherichia coli; Flavin Mononucleotide; Homocysteine; Transferases; Ultracentrifugation; Vitamin B 12 | 1967 |
N5-methyltetrahydrofolate-homocysteine transmethylase. Role of S-adenosylmethionine in vitamin B12-dependent methionine synthesis.
Topics: Alkylation; Escherichia coli; Homocysteine; Iodides; Methionine; Nucleosides; Transferases; Vitamin B 12 | 1967 |
[Pernicious anemia--funicular spinal disease--pernicious psychosis].
Topics: Anemia, Pernicious; Female; Folic Acid; Homocysteine; Humans; Intestinal Absorption; Isomerases; Methionine; Middle Aged; Neurocognitive Disorders; Spinal Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 1969 |
Vitamin B 12 dependent methionine biosynthesis in cultured mammalian cells.
Topics: Animals; Carbon Isotopes; Carcinoma; Cell Division; Cell Line; Cricetinae; Culture Media; Culture Techniques; Drug Synergism; Folic Acid; Formaldehyde; HeLa Cells; Homocysteine; Humans; Kidney; Laryngeal Neoplasms; Methionine; Stimulation, Chemical; Swine; Transferases; Vitamin B 12 | 1969 |
[A hepato-protector in the treatment of long bed-ridden old persons affected with chronic diseases].
Topics: Aged; Choline; Chronic Disease; Homocysteine; Humans; Liver; Vitamin B 12 | 1969 |
Methylcobalamin as an intermediate in mammalian methionine biosynthesis.
Topics: Animals; Carbon Isotopes; Chromatography, Gel; Electrophoresis; Ethanol; Folic Acid; Homocysteine; Kidney; Methionine; Methylation; Nucleosides; Photochemistry; Solubility; Swine; Transferases; Vitamin B 12 | 1970 |
Hydrocarbon-utilizing microorganism. Relationship of fatty acid composition and biosynthesis to hydrocarbon substrate and to vitamin B 12 level in Corynebacterium simplex.
Topics: Alkanes; Carbon Isotopes; Cobalt; Corynebacterium; Culture Media; Fatty Acids; Folic Acid; Homocysteine; Methionine; Methylation; Nucleosides; Spectrum Analysis; Transferases; Vitamin B 12 | 1970 |
Deranged B 12 metabolism: effects on sulfur amino acid metabolism.
Topics: Adenosine Triphosphate; Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Betaine; Brain Chemistry; Carbon Isotopes; Child, Preschool; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Isomerases; Kidney; Liver; Male; Malonates; Methionine; Methyltransferases; Transferases; Vitamin B 12 | 1970 |
Deranged B 12 metabolism: studies of fibroblasts grown in tissue culture.
Topics: Amino Acid Metabolism, Inborn Errors; Carbon Dioxide; Carbon Isotopes; Coenzyme A; Fibroblasts; Folic Acid; Glutamates; Homocysteine; Humans; Hydroxocobalamin; Isomerases; L-Serine Dehydratase; Male; Malonates; Methionine; Methyltransferases; Propionates; Skin; Vitamin B 12 | 1970 |
Homocystinuria with methylmalonic aciduria: two cases in a sibship.
Topics: Adolescent; Carbon Isotopes; Child, Preschool; Coenzyme A; Female; Fibroblasts; Folic Acid; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Isomerases; L-Serine Dehydratase; Male; Malonates; Methionine; Methyltransferases; Pedigree; Propionates; Skin; Vitamin B 12 | 1970 |
Studies on vitamin B12 metabolism in HeLa cells.
Topics: Adenosine Triphosphate; Carbon Dioxide; Carbon Isotopes; Cell Line; Coenzyme A; Culture Techniques; Enzyme Activation; Folic Acid; HeLa Cells; Homocysteine; Isomerases; Malonates; Methionine; Propionates; Transferases; Vitamin B 12 | 1971 |
Catabolism of betaine and its relationship to cobalamin overproduction.
Topics: Betaine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Choline; Coenzyme A; Glycine; Homocysteine; Methionine; Methylation; Nucleosides; Porphyrins; Pseudomonas; S-Adenosylmethionine; Succinates; Sucrose; Vitamin B 12 | 1971 |
[The role of vitamin B12 in metabolism].
Topics: Animals; Coenzymes; Folic Acid; Homocysteine; Humans; Isomerases; Methylation; Vitamin B 12; Vitamin B 12 Deficiency | 1968 |
Vitamin B 12-dependent methionine biosynthesis in HEp-2 cells.
Topics: Carbon Isotopes; Carcinoma, Squamous Cell; Culture Techniques; Homocysteine; Humans; Laryngeal Neoplasms; Ligases; Methionine; Quaternary Ammonium Compounds; Radioisotopes; Sulfates; Vitamin B 12 | 1968 |
A derangement in B 12 metabolism leading to homocystinemia, cystathioninemia and methylmalonic aciduria.
Topics: Amino Acid Metabolism, Inborn Errors; Aminobutyrates; Brain; Homocysteine; Homocystine; Homocystinuria; Humans; Infant; Kidney; Liver; Male; Malonates; Metabolism, Inborn Errors; Methionine; Sulfides; Transferases; Vitamin B 12 | 1969 |
Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Aminobutyrates; Arteries; Arteriosclerosis; Child; Diet; Homocysteine; Homocystinuria; Humans; Infant, Newborn; Isomerases; Kidney; Ligases; Male; Malonates; Methionine; Vitamin B 12 | 1969 |
Inhibition by L-methionine of the growth of Euglena gracilis in a glutamic acid medium.
Topics: Acetates; Amino Acids; Animals; Biological Transport; Carbon Isotopes; Culture Media; Cysteine; Euglena; Glutamates; Homocysteine; Methionine; Threonine; Vitamin B 12 | 1969 |
The biosynthesis of the methyl groups of choline in Ochromonas malhamensis.
Topics: Alkylation; Amino Alcohols; Choline; Eukaryota; Folic Acid; Homocysteine; In Vitro Techniques; Methionine; Microsomes; Mitochondria; Nucleosides; Phosphatidylcholines; Subcellular Fractions; Vitamin B 12 | 1966 |
First defined media for leptomonas spp. from insects.
Topics: Choline; Culture Media; Eukaryota; Glycine; Homocysteine; Insecta; Lactones; Methionine; Pantothenic Acid; Vitamin B 12 | 1966 |
N5-methyltetrahydrofolate-homocysteine transmethylase. Propylation characteristics with the use of a chemical reducing system and purified enzyme.
Topics: Alkylation; Flavin Mononucleotide; Glycols; Homocysteine; Iodides; Light; Sulfhydryl Compounds; Transferases; Vitamin B 12 | 1967 |
Formation and utilization of methionine by rat liver cells in culture.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Homocysteine; Leucine; Liver; Methionine; Rats; Vitamin B 12 | 1983 |
Homocystinuria--the effects of betaine in the treatment of patients not responsive to pyridoxine.
Topics: Amino Acids; Amino Acids, Sulfur; Betaine; Cystathionine beta-Synthase; Cysteine; Female; Homocysteine; Homocystinuria; Humans; Male; Pyridoxine; Vitamin B 12 | 1983 |
The effect of derivatives of folic acid on the fluorodeoxyuridylate-thymidylate synthetase covalent complex in human colon xenografts.
Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; Deoxyuracil Nucleotides; Female; Fluorodeoxyuridylate; Folic Acid; Homocysteine; Humans; Methyltransferases; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Rectal Neoplasms; Tetrahydrofolates; Thymidylate Synthase; Transplantation, Heterologous; Vitamin B 12 | 1982 |
Homocysteine in the plasma of renal transplant recipients: effects of cofactors for methionine metabolism.
Topics: Adult; Amino Acids; Dipeptides; Disulfides; Female; Folic Acid; Homocysteine; Humans; Kidney Transplantation; Male; Middle Aged; Pyridoxine; Vitamin B 12 | 1981 |
Effective homocysteine metabolism may protect South African blacks against coronary heart disease.
Topics: Adult; Black People; Coronary Disease; Folic Acid; Homocysteine; Humans; Male; Methionine; South Africa; Vitamin B 12; Vitamins; White People | 1995 |
Cerebrospinal fluid homocysteine and the cobalamin status of the brain.
Topics: Brain Chemistry; Chromatography, High Pressure Liquid; Homocysteine; Humans; Male; Middle Aged; Reference Values; Spectrometry, Fluorescence; Vitamin B 12; Vitamin B 12 Deficiency | 1993 |
Can lowering homocysteine levels reduce cardiovascular risk?
Topics: Aged; Cardiovascular Diseases; Carotid Stenosis; Folic Acid; Homocysteine; Humans; Male; Risk Factors; Vitamin B 12 | 1995 |
Higher plasma homocyst(e)ine and increased susceptibility to adverse effects of low folate in early familial coronary artery disease.
Topics: Adult; Aged; Coronary Disease; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Pyridoxine; Regression Analysis; Risk Factors; Vitamin B 12 | 1995 |
Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism.
Topics: Adolescent; Adult; Aged; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Chromatography; Creatinine; Cystathionine beta-Synthase; Female; Folic Acid Deficiency; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Metabolism, Inborn Errors; Methionine; Methyltransferases; Middle Aged; Rats; Rats, Sprague-Dawley; Reference Values; Renal Insufficiency; Sarcosine; Vitamin B 12; Vitamin B 12 Deficiency | 1993 |
Lack of association between plasma homocysteine levels and microangiopathy in type 1 diabetes mellitus.
Topics: Adult; Albuminuria; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Retinopathy; Female; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12 | 1994 |
Prevention of neural tube defects by and toxicity of L-homocysteine in cultured postimplantation rat embryos.
Topics: Adenosylhomocysteinase; Animals; Catalase; Copper; Copper Sulfate; Culture Techniques; Drug Interactions; Embryonic and Fetal Development; Embryonic Development; Female; Homocysteine; Homocystine; Hydrolases; Methionine; Neural Tube Defects; Oxidation-Reduction; Pregnancy; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Stereoisomerism; Teratogens; Vitamin B 12 | 1994 |
Homocysteinemia and schizophrenia as a case of methylation deficiency.
Topics: Adult; Female; Homocysteine; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Schizophrenia; Tetrahydrofolates; Vitamin B 12 | 1994 |
Homocysteine metabolism in pregnancies complicated by neural-tube defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Analysis of Variance; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methylation; Methylmalonic Acid; Neural Tube Defects; Pregnancy; Vitamin B 12 | 1995 |
Homocysteine and coronary artery disease in French Canadian subjects: relation with vitamins B12, B6, pyridoxal phosphate, and folate.
Topics: Adult; Chi-Square Distribution; Coronary Disease; Discriminant Analysis; Female; Folic Acid; France; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Pyridoxal Phosphate; Pyridoxine; Quebec; Regression Analysis; Risk Factors; Sex Factors; Vitamin B 12; Vitamin B Complex | 1995 |
Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis.
Topics: Aged; Aged, 80 and over; Carotid Stenosis; Confidence Intervals; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Odds Ratio; Pyridoxal Phosphate; Pyridoxine; Risk Factors; Ultrasonography; Vitamin B 12 | 1995 |
Plasma homocysteine in relation to serum cobalamin and blood folate in a psychogeriatric population.
Topics: Aged; Aged, 80 and over; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Mental Disorders; Vitamin B 12; Vitamin B 12 Deficiency | 1994 |
Plasma levels of the atherogenic amino acid homocysteine in post-menopausal women with breast cancer treated with tamoxifen.
Topics: Aged; Arteriosclerosis; Breast Neoplasms; Cholesterol; Cysteine; Female; Folic Acid; Homocysteine; Humans; Menopause; Middle Aged; Tamoxifen; Time Factors; Vitamin B 12 | 1995 |
Increase in total plasma homocysteine concentration after cardiac transplantation.
Topics: Adolescent; Adult; Child; Female; Folic Acid; Glomerular Filtration Rate; Heart Transplantation; Hemoglobins; Homocysteine; Humans; Kidney; Male; Middle Aged; Time Factors; Vitamin B 12 | 1995 |
Homocysteine: relationship to serum cobalamin, serum folate, erythrocyte folate, and lobation of neutrophils.
Topics: Adult; Erythrocytes; Folic Acid; Homocysteine; Hospitalization; Humans; Middle Aged; Nervous System Diseases; Neutrophils; Reference Values; Vitamin B 12 | 1994 |
Serum cobalamin deficiency is uncommon in multiple sclerosis.
Topics: Adult; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Multiple Sclerosis; Muscular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 1994 |
Homocysteine and cysteine: determinants of plasma levels in middle-aged and elderly subjects.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Creatinine; Cysteine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Sex Factors; Vitamin B 12; Vitamins | 1994 |
Preoperative methionine loading enhances restoration of the cobalamin-dependent enzyme methionine synthase after nitrous oxide anesthesia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Anesthesia, Inhalation; Female; Homocysteine; Humans; Kinetics; Leukocytes; Male; Methionine; Middle Aged; Nitrous Oxide; Reference Values; Time Factors; Vitamin B 12 | 1994 |
Homocysteine increases as folate decreases in plasma of healthy men during short-term dietary folate and methyl group restriction.
Topics: Adult; Choline; Diet; Folic Acid; Folic Acid Deficiency; Glycine max; Homocysteine; Humans; Male; Methionine; Middle Aged; Nutritional Requirements; Nutritional Status; Vitamin B 12 | 1994 |
Development and reversion of methionine dependence in a human glioma cell line: relation to homocysteine remethylation and cobalamin status.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Brain Neoplasms; Female; Folic Acid; Glioblastoma; Homocysteine; Humans; Methionine; Methylation; Nitrous Oxide; Tumor Cells, Cultured; Vitamin B 12 | 1994 |
Rapid HPLC determination of total homocysteine and other thiols in serum and plasma: sex differences and correlation with cobalamin and folate concentrations in healthy subjects.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Cysteine; Dipeptides; Female; Folic Acid; Homocysteine; Humans; Male; Microchemistry; Middle Aged; Reference Values; Sensitivity and Specificity; Sex Characteristics; Sulfhydryl Compounds; Vitamin B 12 | 1994 |
Identification and perturbation of mutant human fibroblasts based on measurements of methylmalonic acid and total homocysteine in the culture media.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line; Culture Media; Fibroblasts; Homocysteine; Humans; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Mutation; Propionates; Vitamin B 12 | 1993 |
Cobalamin metabolism in cultured human chorionic villus cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Apoenzymes; Biopsy; Cell Division; Cells, Cultured; Chorionic Villi; Homocysteine; Humans; In Vitro Techniques; Methionine; Methylmalonyl-CoA Mutase; Receptors, Cell Surface; Transcobalamins; Vitamin B 12 | 1993 |
Vitamin status and intake as primary determinants of homocysteinemia in an elderly population.
Topics: Aged; Aged, 80 and over; Aging; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Male; Nutritional Status; Pyridoxal Phosphate; Pyridoxine; Vitamin B 12; Vitamin B Complex | 1993 |
Nitrous oxide degradation by cobalamin-dependent methionine synthase: characterization of the reactants and products in the inactivation reaction.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Electrochemistry; Enzyme Activation; Enzyme Stability; Escherichia coli; Homocysteine; Hydrogen-Ion Concentration; Methionine; Methylation; Nitrous Oxide; Oxidation-Reduction; Oxygen; Spectrophotometry; Vitamin B 12 | 1994 |
Nitrous oxide inactivation of cobalamin-dependent methionine synthase from Escherichia coli: characterization of the damage to the enzyme and prosthetic group.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Binding Sites; Electrochemistry; Escherichia coli; Homocysteine; Methionine; Molecular Sequence Data; Nitrous Oxide; Oxidation-Reduction; Peptide Fragments; Peptide Mapping; S-Adenosylmethionine; Tetrahydrofolates; Trypsin; Vitamin B 12 | 1994 |
Plasma homocyst(e)ine, folate, and vitamin B-12 concentrations and risk for early-onset coronary artery disease.
Topics: Adult; Case-Control Studies; Coronary Disease; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Vitamin B 12 | 1994 |
Cobalamin deficiency in the elderly.
Topics: Aged; Homocysteine; Humans; Vitamin B 12; Vitamin B 12 Deficiency | 1993 |
Study on the presence of homocysteine in ovarian follicular fluid.
Topics: Adult; Female; Folic Acid; Follicular Fluid; Homocysteine; Humans; Methionine; Pyridoxine; Reference Values; Vitamin B 12 | 1993 |
Plasma homocysteine concentrations in Japanese patients with non-insulin-dependent diabetes mellitus: effect of parenteral methylcobalamin treatment.
Topics: Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Homocysteine; Humans; Injections, Intramuscular; Male; Middle Aged; Risk Factors; Vitamin B 12 | 1993 |
Cobalamin absorption and serum homocysteine and methylmalonic acid in elderly subjects with low serum cobalamin.
Topics: Aged; Aged, 80 and over; Diagnosis, Differential; Female; Homocysteine; Humans; Intestinal Absorption; Malabsorption Syndromes; Male; Methylmalonic Acid; Prospective Studies; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 1993 |
Hyperhomocysteinemia in patients operated for lower extremity ischaemia below the age of 50--effect of smoking and extent of disease.
Topics: Adult; Arteriosclerosis; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Ischemia; Male; Methionine; Middle Aged; Postoperative Complications; Pyridoxine; Risk Factors; Smoking; Vitamin B 12 | 1993 |
Assignment of enzymatic function to specific protein regions of cobalamin-dependent methionine synthase from Escherichia coli.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Binding Sites; Catalysis; Escherichia coli; Homocysteine; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1993 |
New assay for the rapid determination of plasma holotranscobalamin II levels: preliminary evaluation in cancer patients.
Topics: Adsorption; Chromatography; Glass; Hematologic Tests; Homocysteine; Humans; Hydroxyurea; Microspheres; Neoplasms; Osmolar Concentration; Polycythemia; Reproducibility of Results; Transcobalamins; Vitamin B 12 | 1993 |
Plasma homocysteine and severity of atherosclerosis in young patients with lower-limb atherosclerotic disease.
Topics: Adult; Arteriosclerosis; Cerebrovascular Disorders; Coronary Disease; Fasting; Female; Folic Acid; Homocysteine; Humans; Leg; Male; Methionine; Middle Aged; Pyridoxine; Risk Factors; Vitamin B 12 | 1996 |
Kinetics of total plasma homocysteine in subjects with hyperhomocysteinemia due to folate or cobalamin deficiency.
Topics: Adolescent; Adult; Aged; Female; Folic Acid; Folic Acid Deficiency; Half-Life; Hematinics; Homocysteine; Humans; Kinetics; Male; Methionine; Methylmalonic Acid; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Hyperhomocysteinemia in chronic alcoholism: correlation with folate, vitamin B-12, and vitamin B-6 status.
Topics: Adult; Alcoholism; Blood Cell Count; Erythrocyte Indices; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Pyridoxine; Vitamin B 12 | 1996 |
Elevated plasma concentration of reduced homocysteine in patients with human immunodeficiency virus infection.
Topics: Adult; CD4 Lymphocyte Count; Cysteine; Dipeptides; Female; Folic Acid; HIV Antibodies; HIV Infections; HIV-1; Homocysteine; Humans; Interleukin-2; Lymphocytes; Male; Methionine; Middle Aged; Oxidation-Reduction; Oxidative Stress; Vitamin B 12 | 1996 |
Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study.
Topics: Aged; Aging; Cognition; Homocysteine; Humans; Male; Memory; Middle Aged; Pyridoxine; Reference Values; Space Perception; Vitamin B 12 | 1996 |
Elevated methylmalonic acid and total homocysteine levels show high prevalence of vitamin B12 deficiency after gastric surgery.
Topics: Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Postoperative Complications; Stomach; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Vitamin B-12 deficiency after gastric surgery for obesity.
Topics: Adult; Anastomosis, Roux-en-Y; Female; Gastric Bypass; Gastroplasty; Homocysteine; Humans; Intestinal Absorption; Male; Obesity, Morbid; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Age- and gender-specific reference intervals for total homocysteine and methylmalonic acid in plasma before and after vitamin supplementation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Reference Values; Sex Characteristics; Vitamin B 12; Vitamins | 1996 |
Homocysteine metabolism and risk of myocardial infarction: relation with vitamins B6, B12, and folate.
Topics: Case-Control Studies; Diet; Diet Surveys; Fasting; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Methionine; Methylation; Middle Aged; Myocardial Infarction; Odds Ratio; Pyridoxine; Risk Factors; Vitamin B 12 | 1996 |
Relationship between plasma homocysteine, vitamin status and extracranial carotid-artery stenosis in the Framingham Study population.
Topics: Aged; Aged, 80 and over; Carotid Stenosis; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Male; Pyridoxine; Vitamin B 12 | 1996 |
Treatment of hyperhomocyst(e)inemia: physiological basis.
Topics: Betaine; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 1996 |
Crohn's disease and vitamin B12 metabolism.
Topics: Adult; Crohn Disease; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Transcobalamins; Vitamin B 12 | 1996 |
DNA hypomethylation in inflammatory arthritis: reversal with methotrexate.
Topics: Adult; Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Male; Methotrexate; Middle Aged; Vitamin B 12 | 1996 |
Folate status is the major determinant of fasting total plasma homocysteine levels in maintenance dialysis patients.
Topics: Adult; Aged; Amino Acid Sequence; Cardiovascular Diseases; Cholesterol, HDL; Comorbidity; Creatinine; DNA Mutational Analysis; Female; Folic Acid; Glucose Intolerance; Homocysteine; Humans; Hypertension; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Peritoneal Dialysis; Polymorphism, Restriction Fragment Length; Prevalence; Renal Dialysis; Risk Factors; Smoking; Vitamin B 12 | 1996 |
Genes, greens, and homocysteine.
Topics: Angina Pectoris; Arteriosclerosis; Folic Acid; Homocysteine; Humans; Myocardial Infarction; Prospective Studies; Pyridoxine; Risk Factors; Vitamin B 12 | 1996 |
Hyperhomocysteinaemia and premature coronary artery disease in the Chinese.
Topics: Adult; Case-Control Studies; China; Cholesterol; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Hong Kong; Humans; Male; Middle Aged; Prevalence; Risk Factors; Smoking; Vitamin B 12 | 1996 |
Cobalamin-independent methionine synthase from Escherichia coli: a zinc metalloenzyme.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Binding Sites; Cadmium Chloride; Circular Dichroism; Cloning, Molecular; Cysteine; Escherichia coli; Fourier Analysis; Homocysteine; Metalloproteins; Mutagenesis, Site-Directed; Protein Conformation; Spectrum Analysis; Tetrahydrofolates; Vitamin B 12; X-Rays; Zinc | 1996 |
Plasma total homocysteine in healthy subjects: sex-specific relation with biological traits.
Topics: Adult; Female; Folic Acid; Health Status; Homocysteine; Humans; Male; Middle Aged; Pyridoxal Phosphate; Reference Values; Regression Analysis; Sex Characteristics; Vitamin B 12 | 1996 |
Determinants of hyperhomocysteinemia: a matter of nature and nurture.
Topics: Female; Folic Acid; Homocysteine; Humans; Male; Sex Characteristics; Vitamin B 12 | 1996 |
Cobalamin and folate deficiencies.
Topics: Biomarkers; Chemistry, Clinical; Folic Acid; Folic Acid Deficiency; Hematology; Homocysteine; Humans; Methylmalonic Acid; Practice Guidelines as Topic; Predictive Value of Tests; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Are different reference intervals for methylmalonic acid and total homocysteine necessary in elderly people?
Topics: Adult; Aged; Aged, 80 and over; Aging; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Nutritional Status; Reference Values; Vitamin B 12 | 1996 |
Determinants and vitamin responsiveness of intermediate hyperhomocysteinemia (> or = 40 micromol/liter). The Hordaland Homocysteine Study.
Topics: Adult; Aged; Female; Folic Acid; Gene Frequency; Homocysteine; Homozygote; Humans; Male; Mass Screening; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Norway; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
The significance of subnormal serum vitamin B12 concentration in older people: a case control study.
Topics: Age Factors; Aged; Aged, 80 and over; Case-Control Studies; Female; Geriatric Assessment; Homocysteine; Humans; Leukocyte Count; Male; Mental Status Schedule; Neurologic Examination; Neutrophils; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Hyperhomocysteinaemia--a common finding in a psychogeriatric population.
Topics: Aged; Aged, 80 and over; Dementia; Female; Folic Acid; Homocysteine; Humans; Male; Vascular Diseases; Vitamin B 12 | 1996 |
The common 'thermolabile' variant of methylene tetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Neural Tube Defects; Oxidoreductases; Phenotype; Risk Factors; Vascular Diseases; Vitamin B 12 | 1996 |
Hyperhomocysteinemia confers an independent increased risk of atherosclerosis in end-stage renal disease and is closely linked to plasma folate and pyridoxine concentrations.
Topics: Aged; Aging; Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Odds Ratio; Osmolar Concentration; Peritoneal Dialysis, Continuous Ambulatory; Pyridoxine; Renal Dialysis; Risk Factors; Sex Distribution; Vitamin B 12 | 1996 |
Hormone replacement therapy and cobalamin status in elderly women.
Topics: Aged; Aging; Cohort Studies; Estrogen Replacement Therapy; Female; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12 | 1996 |
Decreased methylene tetrahydrofolate reductase activity due to the 677C-->T mutation in families with spina bifida offspring.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Aged; Child; Cysteine; Female; Folic Acid; Genetic Linkage; Genotype; Homocysteine; Homozygote; Humans; Lod Score; Lymphocytes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Netherlands; Oxidoreductases; Point Mutation; Risk Factors; Spinal Dysraphism; Vitamin B 12 | 1996 |
Folic acid fortification of the food supply. Potential benefits and risks for the elderly population.
Topics: Aged; Aged, 80 and over; Anemia, Macrocytic; Cross-Sectional Studies; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Regression Analysis; Risk; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Metabolism, Inborn Errors; Amino Acid Sequence; Base Sequence; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; DNA, Complementary; Homocysteine; Humans; Molecular Sequence Data; Mutation; Sequence Alignment; Vitamin B 12 | 1996 |
[The prevalence of hyperhomocysteinemia in thromboangiitis obliterans. Does homocysteine play a role pathogenetically?].
Topics: Adult; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Prevalence; Pyridoxine; Risk Factors; Smoking; Statistics, Nonparametric; Thromboangiitis Obliterans; Time Factors; Vitamin B 12 | 1996 |
Alcoholic cirrhosis and cobalamin metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Biomarkers; Biopsy, Needle; Chronic Disease; Female; Follow-Up Studies; Homocysteine; Humans; Liver Cirrhosis, Alcoholic; Male; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Plasma methylmalonic acid in relation to serum cobalamin and plasma homocysteine in a psychogeriatric population and the effect of cobalamin treatment.
Topics: Aged; Biomarkers; Case-Control Studies; Drug Monitoring; Female; Geriatric Psychiatry; Homocysteine; Humans; Male; Mental Disorders; Methylmalonic Acid; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Fasting and post-methionine homocyst(e)ine levels in a healthy Australian population.
Topics: Adult; Aged; Australia; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Reference Values; Vitamin B 12 | 1997 |
[Familial hyperhomocysteinemia with early development of atherosclerosis].
Topics: Adult; Aged; Arteriosclerosis; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Myocardial Infarction; Vitamin B 12 | 1996 |
Abnormal homocysteine metabolism in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Fasting; Female; Homocysteine; Humans; Male; Methionine; Methotrexate; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Fasting total plasma homocysteine and atherosclerotic peripheral vascular disease.
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Case-Control Studies; Chromatography, Ion Exchange; Fasting; Female; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Risk Factors; Vitamin B 12 | 1997 |
Correlation between plasma homocyst(e)ine and aortic atherosclerosis.
Topics: Aged; Aorta, Thoracic; Aortic Diseases; Arteriosclerosis; Echocardiography, Transesophageal; Female; Folic Acid; Homocysteine; Humans; Male; Multivariate Analysis; Observer Variation; Pyridoxal Phosphate; Pyridoxine; Risk Factors; Vitamin B 12 | 1997 |
Marginal folate deficiency as a possible cause of hyperhomocystinaemia in stroke patients.
Topics: Aged; Case-Control Studies; Cerebrovascular Disorders; Creatinine; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Time Factors; Vitamin B 12 | 1997 |
Plasma total homocysteine, B vitamins, and risk of coronary atherosclerosis.
Topics: Adult; Aging; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Pyridoxal Phosphate; Risk Factors; Sex Characteristics; Vitamin B 12; Vitamin B Complex | 1997 |
Association between plasma homocysteine and extracranial carotid arterial disease in older persons.
Topics: Aged; Aged, 80 and over; Carotid Artery Diseases; Female; Folic Acid; Homocysteine; Humans; Male; Prospective Studies; Risk Factors; Vitamin B 12 | 1997 |
Enhanced levels of biochemical markers for cobalamin deficiency in totally gastrectomized rats: uncoupling of the enhancement from the severity of spongy vacuolation in spinal cord.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Pernicious; Animals; Bacteria, Anaerobic; Citrates; Cystathionine; Disease Models, Animal; Erythromycin; Gastrectomy; Homocysteine; Humans; Intestines; Lincomycin; Male; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Postgastrectomy Syndromes; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Diseases; Vacuoles; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Atherogenesis and the homocysteine-folate-cobalamin triad: do we need standardized analyses?
Topics: Adult; Aged; Aged, 80 and over; Animals; Arteriosclerosis; Biomarkers; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Transcobalamins; Vitamin B 12 | 1997 |
Vitamin intake: a possible determinant of plasma homocyst(e)ine among middle-aged adults.
Topics: Analysis of Variance; Arteriosclerosis; Carotid Arteries; Case-Control Studies; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nutrition Surveys; Pyridoxine; Regression Analysis; Sampling Studies; United States; Vitamin B 12 | 1997 |
Home parenteral nutrition and vitamin B12 status.
Topics: Adult; Aged; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Nutritional Status; Parenteral Nutrition, Home; Reference Values; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Cyanocobalamin [c-lactam] inhibits vitamin B12 and causes cytotoxicity in HL60 cells: methionine protects cells completely.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Death; Enzyme Inhibitors; Folic Acid; HL-60 Cells; Homocysteine; Humans; Hydroxocobalamin; Methionine; Methylmalonyl-CoA Mutase; Propionates; Tetrahydrofolates; Vitamin B 12 | 1997 |
Cobalamin-dependent methionine synthase is a modular protein with distinct regions for binding homocysteine, methyltetrahydrofolate, cobalamin, and adenosylmethionine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Binding Sites; Escherichia coli; Homocysteine; Methylation; Protein Binding; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1997 |
Effects of methylcobalamin on the proliferation of androgen-sensitive or estrogen-sensitive malignant cells in culture and in vivo.
Topics: Androgens; Animals; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Estrogens; Female; Homocysteine; Humans; Leydig Cell Tumor; Male; Mammary Neoplasms, Animal; Methionine; Mice; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Testicular Neoplasms; Tumor Cells, Cultured; Vitamin B 12 | 1997 |
Diagnosis of cobalamin deficiency: the old and the new.
Topics: Erythrocyte Volume; Hematologic Tests; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Some vitamin sources relating to plasma homocysteine provide not only folate but also vitamins B-12 and B-6.
Topics: Aged; Diet; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Pyridoxine; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Elevated homocyst(e)ine levels with preeclampsia.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Parity; Pre-Eclampsia; Pregnancy; Risk Factors; Vascular Diseases; Vitamin B 12 | 1997 |
Purification and assay of cobalamin-dependent methionine synthase from Escherichia coli.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Carbon Radioisotopes; Escherichia coli; Homocysteine; Methionine; Spectrophotometry; Tetrahydrofolates; Vitamin B 12 | 1997 |
Plasma total homocysteine concentrations in epileptic patients taking anticonvulsants.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant; Male; Vitamin B 12 | 1997 |
Mutation (677 C to T) in the methylenetetrahydrofolate reductase gene aggravates hyperhomocysteinemia in hemodialysis patients.
Topics: Adult; Aged; Alleles; Cohort Studies; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Renal Dialysis; Renal Insufficiency; Vitamin B 12 | 1997 |
Homocysteine accumulation in human ovarian carcinoma ascitic/cystic fluids possibly caused by metabolic alteration of the methionine cycle in ovarian carcinoma cells.
Topics: Adult; Aged; Ascitic Fluid; Cysteine; Female; Folic Acid; Glycine; Homocysteine; Humans; Methionine; Methylation; Middle Aged; Ovarian Neoplasms; Vitamin B 12 | 1997 |
Increased concentrations of homocysteine in the cerebrospinal fluid in patients with fibromyalgia and chronic fatigue syndrome.
Topics: Adult; Cystathionine; Fatigue Syndrome, Chronic; Female; Fibromyalgia; Homocysteine; Humans; Methionine; Middle Aged; Models, Biological; Vitamin B 12 | 1997 |
Folate depletion induced by methotrexate affects methionine synthase activity and its susceptibility to inactivation by nitrous oxide.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Anesthetics, Inhalation; Female; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Methotrexate; Methylation; Nitrous Oxide; Tumor Cells, Cultured; Vitamin B 12 | 1997 |
Association between plasma total homocysteine and parental history of cardiovascular disease in children with familial hypercholesterolemia.
Topics: Adolescent; Age Distribution; Cardiovascular Diseases; Child; Diet; Family Health; Female; Folic Acid; Heterozygote; Homocysteine; Humans; Hyperlipoproteinemia Type II; Lipids; Male; Methylenetetrahydrofolate Reductase (NADPH2); Multivariate Analysis; Oxidoreductases Acting on CH-NH Group Donors; Parents; Point Mutation; Prevalence; Risk Factors; Sex Distribution; Vitamin B 12 | 1997 |
Altered folate and vitamin B12 metabolism in families with spina bifida offspring.
Topics: Adolescent; Adult; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk; Spinal Dysraphism; Statistics, Nonparametric; Vitamin B 12 | 1997 |
Vitamin B6 status, MTHFR and hyperhomocysteinaemia.
Topics: Adult; Alleles; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Pyridoxine; Vitamin B 12 | 1997 |
Plasma total homocysteine in a representative sample of 972 British men and women aged 65 and over.
Topics: Aged; alpha 1-Antichymotrypsin; Calcium; Creatinine; England; Female; Folic Acid; Homocysteine; Humans; Lutein; Male; Nutritional Status; Random Allocation; Reference Values; Regression Analysis; Risk Factors; Urea; Vascular Diseases; Vitamin B 12; Zinc | 1997 |
Homocysteine as a risk factor for vascular disease. Enhanced collagen production and accumulation by smooth muscle cells.
Topics: Animals; Arteriosclerosis; Cell Division; Cells, Cultured; Collagen; Homocysteine; Male; Muscle, Smooth, Vascular; Rabbits; Risk Factors; Vitamin B 12 | 1997 |
Homocysteine levels and cardiovascular disease.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Pyridoxine; Vitamin B 12; Vitamins | 1997 |
Elevated plasma levels of reduced homocysteine in common variable immunodeficiency--a marker of enhanced oxidative stress.
Topics: Adult; beta Carotene; Biomarkers; CD4 Lymphocyte Count; Common Variable Immunodeficiency; Cysteine; Dipeptides; Female; Folic Acid; Homocysteine; Humans; Lipid Peroxidation; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Sulfhydryl Compounds; Vitamin B 12; Vitamin E | 1997 |
Association between plasma homocysteine and coronary artery disease in older persons.
Topics: Age Factors; Aged; Aged, 80 and over; Coronary Disease; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Prevalence; Sex Factors; Vitamin B 12 | 1997 |
[Megaloblastic anemia: rapid and economical study].
Topics: Adolescent; Adult; Algorithms; Anemia, Megaloblastic; Cost Control; Diagnosis, Differential; Diagnostic Tests, Routine; Female; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Histidine; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Hematologic; Reticulocyte Count; Retrospective Studies; Sensitivity and Specificity; Time Factors; Urinalysis; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Vitamin B-12 and folic acid supplementation.
Topics: Aged; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Serum methylmalonic acid and total homocysteine in patients with suspected cobalamin deficiency: a clinical study based on gastrointestinal histopathological findings.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Gastric Mucosa; Homocysteine; Humans; Intestinal Mucosa; Male; Methylmalonic Acid; Middle Aged; Neutrophils; Prospective Studies; Schilling Test; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Poor metabolic control, early age at onset, and marginal folate deficiency are associated with increasing levels of plasma homocysteine in insulin-dependent diabetes mellitus. A five-year follow-up study.
Topics: Adult; Age of Onset; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12 | 1997 |
Changes in protonation associated with substrate binding and Cob(I)alamin formation in cobalamin-dependent methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Catalysis; Cobalt; Cyclic N-Oxides; Enzyme Activation; Escherichia coli; Ferricyanides; Homocysteine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Oxidation-Reduction; Phenolsulfonphthalein; Photolysis; Protein Binding; Protons; Spectrophotometry; Tetrahydrofolates; Vitamin B 12 | 1997 |
Cobalamin-dependent methionine synthase from Escherichia coli: involvement of zinc in homocysteine activation.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Catalysis; Edetic Acid; Escherichia coli; Homocysteine; Methyl Methanesulfonate; Methylation; Mutagenesis; Protein Binding; Protons; Recombinant Proteins; Spectrophotometry; Spectrum Analysis; Tetrahydrofolates; Vitamin B 12; Zinc | 1997 |
Elevated fasting total plasma homocysteine levels and cardiovascular disease outcomes in maintenance dialysis patients. A prospective study.
Topics: Adult; Aged; Arteriosclerosis; Blood Glucose; Cardiovascular Diseases; Cholesterol, HDL; Cohort Studies; Comorbidity; Diabetes Mellitus; Fasting; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis; Proportional Hazards Models; Prospective Studies; Pyridoxine; Renal Dialysis; Single-Blind Method; Smoking; Treatment Outcome; Vitamin B 12 | 1997 |
Consequences of hyperhomocyst(e)inemia on vascular function in atherosclerotic monkeys.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arteriosclerosis; Carotid Arteries; Carotid Stenosis; Cholesterol; Collagen; Diet, Atherogenic; Enzyme Activation; Folic Acid; Homocysteine; Homocystine; Hypercholesterolemia; Leg; Macaca fascicularis; Nitroprusside; Protein C; Pyridoxine; Thrombomodulin; Vasodilation; Vasomotor System; Vitamin B 12 | 1997 |
Hyperhomocysteinaemia in black patients with cerebral thrombosis.
Topics: Black People; Case-Control Studies; Cholesterol; Creatine; Female; Homocysteine; Humans; Intracranial Embolism and Thrombosis; Male; Middle Aged; Pyridoxine; Vitamin B 12 | 1997 |
Oral contraceptives did not affect biochemical folate indexes and homocysteine concentrations in adolescent females.
Topics: Adolescent; Adult; Alcohol Drinking; Contraceptives, Oral; Female; Folic Acid; Homocysteine; Humans; Life Style; Nutritional Status; Smoking; Surveys and Questionnaires; Vitamin B 12 | 1998 |
Plasma total homocysteine levels in hyperthyroid and hypothyroid patients.
Topics: Adult; Aged; Arteriosclerosis; Cardiovascular Diseases; Cholesterol; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Multivariate Analysis; Risk Factors; Thyroxine; Triiodothyronine; Vitamin B 12 | 1998 |
Vitamins and progression of atherosclerosis in hyper-homocyst(e)inaemia.
Topics: Aged; Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Pyridoxine; Vitamin B 12; Vitamins | 1998 |
Correlates of plasma total homocysteine in patients with hyperlipidaemia.
Topics: Adult; Age Factors; Aged; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Regression Analysis; Sex Factors; Vitamin B 12 | 1997 |
Cystathionine-beta-synthase deficiency: detection of heterozygotes by the ratios of homocysteine to cysteine and folate.
Topics: Adult; Aged; Cystathionine beta-Synthase; Cysteine; Female; Folic Acid; Genetic Carrier Screening; Homocysteine; Homocystinuria; Humans; Male; Middle Aged; Vitamin B 12 | 1998 |
Plasma total-homocysteine in anorexia nervosa.
Topics: Adolescent; Aging; Anorexia Nervosa; Child; Chromatography, High Pressure Liquid; Creatinine; Female; Folic Acid; Homocysteine; Humans; Reference Values; Vitamin B 12 | 1998 |
The neurochemical markers in cerebrospinal fluid to differentiate between aseptic and tuberculous meningitis.
Topics: Adult; Amino Acids; Aspartic Acid; Biomarkers; Diagnosis, Differential; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Homocysteine; Humans; Male; Meningitis, Aseptic; Middle Aged; Nitrites; Tryptophan; Tuberculosis, Meningeal; Vitamin B 12 | 1998 |
A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?
Topics: Adenine; Adult; Cytosine; Female; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Prevalence; Pyridoxine; Vitamin B 12 | 1998 |
Variability and determinants of total homocysteine concentrations in plasma in an elderly population.
Topics: Aged; Aging; Blood Pressure; Cholesterol; Female; Folic Acid; Homocysteine; Humans; Male; Regression Analysis; Reproducibility of Results; Seasons; Sex Factors; Vitamin B 12 | 1998 |
[Influence of levels of vitamin B2, B12, and folic acid on the values of basal homocysteinemia and after methionine overload].
Topics: Folic Acid; Homocysteine; Humans; Methionine; Middle Aged; Pyridoxine; Vitamin B 12 | 1998 |
Hyperhomocyst(e)inemia in renal transplant recipients with and without cyclosporine.
Topics: Arteriosclerosis; Case-Control Studies; Creatinine; Cyclosporine; Female; Folic Acid; Homocysteine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Risk Factors; Vitamin B 12 | 1998 |
Association between plasma homocysteine and peripheral arterial disease in older persons.
Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Peripheral Vascular Diseases; Prevalence; Risk Factors; Vitamin B 12 | 1998 |
Serum homocysteine and methylmalonic acid in patients with rheumatoid arthritis and cobalaminopenia.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Pilot Projects; Retrospective Studies; Vitamin B 12 | 1998 |
Methylenetetrahydrofolate reductase deficiency in a patient with phenotypic findings of Angelman syndrome.
Topics: Angelman Syndrome; Child; Diagnosis, Differential; Homocysteine; Homocystinuria; Humans; Male; Metabolism, Inborn Errors; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Phenotype; Vitamin B 12 | 1998 |
Major determinants of hyperhomocysteinemia in peritoneal dialysis patients.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Aged; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Osmolar Concentration; Oxidoreductases; Peritoneal Dialysis; Polymorphism, Genetic; Vitamin B 12 | 1998 |
Homocysteine and vascular disease.
Topics: Dietary Supplements; Folic Acid; Homocysteine; Humans; Pyridoxine; Risk Factors; Vascular Diseases; Vitamin B 12 | 1998 |
Total serum homocysteine in senile dementia of Alzheimer type.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biological Transport, Active; Case-Control Studies; Cognition; Creatinine; Diet; Female; Folic Acid; Homocysteine; Humans; Learning; Male; Memory; Prospective Studies; Psychiatric Status Rating Scales; Reference Values; Regression Analysis; Statistics, Nonparametric; Vitamin B 12; Vitamin B 12 Deficiency | 1998 |
Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women.
Topics: Creatinine; Deoxyuracil Nucleotides; Diet; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Lymphocytes; Malondialdehyde; Middle Aged; Mitogens; Nutritional Requirements; Postmenopause; Thymine Nucleotides; Vitamin B 12 | 1998 |
[Plasma homocysteine levels in patients with ischemic cerebral infarction].
Topics: Brain Ischemia; Cerebral Infarction; Chromatography, High Pressure Liquid; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Regression Analysis; Risk Factors; Vitamin B 12 | 1998 |
Neural-tube defects are associated with low concentrations of cobalamin (vitamin B12) in amniotic fluid.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amniocentesis; Amniotic Fluid; Case-Control Studies; Cysteine; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Methionine; Methylation; Neural Tube Defects; Pilot Projects; Pregnancy; Reference Values; Vitamin B 12 | 1998 |
Functionally null mutations in patients with the cblG-variant form of methionine synthase deficiency.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line; Child; Cloning, Molecular; Codon, Terminator; DNA, Complementary; Female; Fibroblasts; Frameshift Mutation; Genetic Complementation Test; Genetic Variation; Homocysteine; Homocystinuria; Humans; Infant, Newborn; Introns; Male; Methionine; Nuclear Family; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Transcription, Genetic; Vitamin B 12 | 1998 |
Disruption of a regulatory system involving cobalamin distribution and function in a methionine-dependent human glioma cell line.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Feedback; Glioma; Homocysteine; Humans; Methionine; Microsomes; Mitochondria; Nitrous Oxide; Receptors, Cell Surface; Tumor Cells, Cultured; Vitamin B 12 | 1998 |
Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins: the Atherosclerosis Risk in Communities (ARIC) study.
Topics: Arteriosclerosis; Cohort Studies; Coronary Disease; Dietary Supplements; Fasting; Female; Folic Acid; Homocysteine; Humans; Incidence; Male; Middle Aged; Polymorphism, Genetic; Prospective Studies; Pyridoxal Phosphate; Risk Factors; Vitamin B 12 | 1998 |
Vitamin supplementation during weight reduction--favourable effect on homocysteine metabolism.
Topics: Adult; Diet, Reducing; Dietary Supplements; Energy Intake; Female; Folic Acid; Homocysteine; Humans; Male; Obesity; Pyridoxine; Statistics, Nonparametric; Vitamin B 12; Weight Loss | 1998 |
A common mutation in the methylenetetrahydrofolate reductase gene and risk of coronary heart disease: results among U.S. men.
Topics: Adult; Aged; Alleles; Case-Control Studies; Confidence Intervals; Coronary Disease; Diet; Folic Acid; Follow-Up Studies; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Riboflavin; Risk Factors; Smoking; United States; Vitamin B 12 | 1998 |
Food-bound B12 absorption and serum total homocysteine in patients with low serum B12 levels.
Topics: Adult; Aged; Aged, 80 and over; Blood Cell Count; Female; Folic Acid; Food; Gastrins; Homocysteine; Humans; Intestinal Absorption; Male; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 1998 |
Dietary intake of cobalamin in elderly people who have abnormal serum cobalamin, methylmalonic acid and homocysteine levels.
Topics: Aged; Aged, 80 and over; Diet; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Nutritional Status; Prospective Studies; Vitamin B 12 | 1998 |
Plasma homocysteine, vitamin B6, vitamin B12 and folic acid in end-stage renal disease during low-dose supplementation with folic acid.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Pyridoxine; Renal Dialysis; Vitamin B 12 | 1998 |
Homocysteine, B vitamins, and vascular-access thrombosis in patients treated with hemodialysis.
Topics: Adult; Aged; Aged, 80 and over; Arteriovenous Shunt, Surgical; Blood Vessel Prosthesis; Erythrocytes; Female; Folic Acid; Genotype; Graft Occlusion, Vascular; Homocysteine; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Pyridoxine; Renal Dialysis; Risk Factors; Thrombophilia; Vitamin B 12 | 1998 |
The diagnostic value of serum homocysteine concentration as a risk factor for coronary artery disease.
Topics: Coronary Disease; Demography; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Lipids; Lipoproteins; Male; Middle Aged; Odds Ratio; Retrospective Studies; Risk Factors; ROC Curve; Surveys and Questionnaires; Vitamin B 12 | 1998 |
[Thrombosis of the superior vena cava, hemolytic anemia and hyper-homocysteinemia].
Topics: Adult; Anemia, Hemolytic; Homocysteine; Humans; Male; Thrombophlebitis; Vena Cava, Superior; Vitamin B 12; Vitamin B 12 Deficiency | 1998 |
The effect of vitamin B12 deficiency on older veterans and its relationship to health.
Topics: Aged; Aged, 80 and over; Alcohol Drinking; Analysis of Variance; Cognition Disorders; Cross-Sectional Studies; Educational Status; Female; Geriatric Assessment; Homocysteine; Humans; Income; Male; Methylmalonic Acid; Oklahoma; Reproducibility of Results; Veterans; Vitamin B 12; Vitamin B 12 Deficiency | 1998 |
Venous thrombosis and hyperhomocysteinaemia.
Topics: Adult; Anticoagulants; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Recurrence; Risk Factors; Venous Thrombosis; Vitamin B 12 | 1998 |
Vitamins B6, B12, and folate: association with plasma total homocysteine and risk of coronary atherosclerosis.
Topics: Adult; Aged; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Pyridoxine; Regression Analysis; Risk Factors; Vitamin B 12 | 1998 |
Reliability of biochemical parameters used in prenatal diagnosis of combined methylmalonic aciduria and homocystinuria.
Topics: Amino Acid Metabolism, Inborn Errors; Amniocentesis; Amniotic Fluid; Cells, Cultured; Chorion; Chorionic Villi Sampling; Cobamides; Female; Gestational Age; Homocysteine; Homocystinuria; Humans; Male; Methylmalonic Acid; Pregnancy; Propionates; Tetrahydrofolates; Vitamin B 12 | 1998 |
[A correlation study on homocysteine metabolism in pregnant women and neural tube defects in urban and rural areas].
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Random Allocation; Rural Health; Urban Health; Vitamin B 12 | 1997 |
Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Male; Memory Disorders; Middle Aged; Polymorphism, Genetic; Predictive Value of Tests; Risk Factors; Vascular Diseases; Vitamin B 12 | 1998 |
Absorption of dietary and supplemental folate in women with prior pregnancies with neural tube defects and controls.
Topics: Absorption; Adult; Biological Availability; Diet; Dietary Supplements; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Pteroylpolyglutamic Acids; Vitamin B 12; Zinc | 1998 |
The effect of a common methylenetetrahydrofolate reductase mutation on levels of homocysteine, folate, vitamin B12 and on the risk of premature atherosclerosis.
Topics: Adult; Age of Onset; Arteriosclerosis; DNA Mutational Analysis; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Risk Factors; Vitamin B 12 | 1998 |
Does the polymorphism 677C-T of the 5,10-methylenetetrahydrofolate reductase gene contribute to homocysteine-related vascular disease?
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adolescent; Adult; Aged; Aged, 80 and over; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases; Polymorphism, Genetic; Risk Factors; Vascular Diseases; Vitamin B 12 | 1998 |
Workshop on Folate, B12, and Choline. Sponsored by the Panel on Folate and other B vitamins of the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine, Washington, D.C., March 3-4,
Topics: Biological Availability; Biomarkers; Cardiovascular Diseases; Choline; Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Male; Neoplasms; Neural Tube Defects; Nutrition Policy; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Cobalamin deficiency in general practice. Assessment of the diagnostic utility and cost-benefit analysis of methylmalonic acid determination in relation to current diagnostic strategies.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cohort Studies; Cost-Benefit Analysis; Family Practice; Female; Folic Acid; Homocysteine; Humans; Infant; Male; Methylmalonic Acid; Middle Aged; Practice Patterns, Physicians'; Reference Standards; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Plasma total homocysteine and cysteine in relation to glomerular filtration rate in diabetes mellitus.
Topics: Adult; Aged; Aged, 80 and over; Aging; Creatinine; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Insulin; Middle Aged; Vitamin B 12 | 1999 |
Effect of MTHFR 677C>T on plasma total homocysteine levels in renal graft recipients.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Homozygote; Humans; Kidney Transplantation; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors; Tissue Donors; Vitamin B 12 | 1999 |
Increased plasma levels of homocysteine and other thiol compounds in rheumatoid arthritis women.
Topics: Adult; Amino Acids; Arthritis, Rheumatoid; Cysteine; Female; Folic Acid; Glutathione; Glycine; Homocysteine; Humans; Middle Aged; Vitamin B 12 | 1999 |
Changes in homocysteine levels during normal pregnancy.
Topics: Adult; Case-Control Studies; Cohort Studies; Confidence Intervals; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Pregnancy; Serum Albumin; Vitamin B 12 | 1999 |
Elevated plasma concentrations of homocysteine in antiepileptic drug treatment.
Topics: Age Factors; Ambulatory Care; Anticonvulsants; Carbamazepine; Convulsants; Depression, Chemical; Epilepsy; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Pyridoxine; Risk Factors; Sex Factors; Valproic Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 1999 |
Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers.
Topics: Aged; Biomarkers, Tumor; Case-Control Studies; Folic Acid; Fruit; Homocysteine; Humans; Logistic Models; Male; Methylation; Middle Aged; Odds Ratio; Pancreatic Neoplasms; Pyridoxine; Risk; Smoking; Vegetables; Vitamin B 12 | 1999 |
A prospective study on folate, B12, and pyridoxal 5'-phosphate (B6) and breast cancer.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Case-Control Studies; Cohort Studies; Confidence Intervals; Female; Folic Acid; Homocysteine; Humans; Incidence; Maryland; Menopause; Middle Aged; Odds Ratio; Postmenopause; Prospective Studies; Pyridoxal Phosphate; Pyridoxine; Reproductive History; Risk Factors; Vitamin B 12 | 1999 |
Distribution of and factors associated with serum homocysteine levels in children: Child and Adolescent Trial for Cardiovascular Health.
Topics: Adolescent; Cardiovascular Diseases; Cross-Sectional Studies; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Male; Pyridoxine; Reference Values; Regression Analysis; Risk Factors; Vitamin B 12 | 1999 |
Prevalence and determinants of hyperhomocysteinemia in hemodialysis and peritoneal dialysis.
Topics: Creatinine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Peritoneal Dialysis; Prevalence; Pyridoxine; Renal Dialysis; Smoking; Time Factors; Vitamin B 12 | 1999 |
Methylene tetrahydrofolate reductase genotype and the risk and extent of coronary artery disease in a population with low plasma folate.
Topics: Case-Control Studies; Cholesterol; Coronary Disease; Folic Acid; Genotype; Homocysteine; Humans; Lipoproteins, HDL; Methylenetetrahydrofolate Dehydrogenase (NADP); Odds Ratio; Polymerase Chain Reaction; Regression Analysis; Risk; Turkey; Vitamin B 12 | 1999 |
Effect of hydrazine upon vitamin B12-dependent methionine synthase activity and the sulphur amino acid pathway in isolated rat hepatocytes.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acids, Sulfur; Animals; Carcinogens; Cell Survival; Culture Media; Cysteine; Cytosol; Enzyme Inhibitors; Homocysteine; Hydrazines; Liver; Male; Nitroarginine; Rats; Rats, Wistar; Taurine; Vitamin B 12 | 1999 |
Holotranscobalamin - a sensitive marker of cobalamin malabsorption.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Atrophy; Female; Gastric Mucosa; Homocysteine; Humans; Intestinal Absorption; Male; Methylmalonic Acid; Middle Aged; Stomach; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Plasma homocysteine concentration in a Belgian school-age population.
Topics: Adolescent; Belgium; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Male; Puberty; Vitamin B 12 | 1999 |
Hyperhomocysteinemia but not the C677T mutation of methylenetetrahydrofolate reductase is an independent risk determinant of carotid wall thickening. The Perth Carotid Ultrasound Disease Assessment Study (CUDAS)
Topics: Adult; Aged; Amino Acid Substitution; Arteriosclerosis; Carotid Arteries; Carotid Stenosis; Comorbidity; Diet; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Obesity; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Pyridoxine; Risk Factors; Smoking; Tunica Intima; Ultrasonography; Vitamin B 12; Western Australia | 1999 |
Genetic polymorphisms in methylenetetrahydrofolate reductase and methionine synthase, folate levels in red blood cells, and risk of neural tube defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Child; Child, Preschool; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Infant; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Prevalence; Risk; Vitamin B 12 | 1999 |
Determinants of fasting and post-methionine homocysteine levels in families predisposed to hyperhomocysteinemia and premature vascular disease.
Topics: Adult; Age Factors; Amino Acid Substitution; Arteriosclerosis; Body Mass Index; Comorbidity; Fasting; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Lipids; Male; Menopause; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Pyridoxine; Smoking; Vitamin B 12 | 1999 |
Folate-homocysteine interrelations: potential new markers of folate status.
Topics: Adult; Dose-Response Relationship, Drug; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Models, Biological; Sensitivity and Specificity; Time Factors; Vitamin B 12 | 1999 |
Fasting and post-methionine homocysteine levels in NIDDM. Determinants and correlations with retinopathy, albuminuria, and cardiovascular disease.
Topics: Administration, Oral; Adult; Aged; Albuminuria; Analysis of Variance; Blood Pressure; Cardiovascular Diseases; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Postmenopause; Premenopause; Pyridoxal Phosphate; Regression Analysis; Risk Factors; Vitamin B 12 | 1999 |
Supplementation with vitamin B12 decreases homocysteine and methylmalonic acid but also serum folate in patients with end-stage renal disease.
Topics: Adult; Aged; Dietary Supplements; Female; Folic Acid; Folic Acid Antagonists; Genotype; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Vitamin B 12 | 1999 |
What's the use of oral vitamin B12?
Topics: Administration, Oral; Homocysteine; Humans; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Folate and homocysteine metabolism in copper-deficient rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Copper; Erythrocytes; Folic Acid; Homocysteine; Liver; Male; Rats; Rats, Sprague-Dawley; Tetrahydrofolates; Vitamin B 12 | 1999 |
Homocyst(e)ine, vitamins and genetic interactions in vascular disease.
Topics: Arteriosclerosis; Female; Genotype; Homocysteine; Humans; Male; Middle Aged; Pyridoxine; Risk Factors; Thrombophlebitis; Vitamin B 12 | 1999 |
Genetic and nongenetic factors influencing plasma homocysteine levels in patients with ischemic cerebrovascular disease and in healthy control subjects.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Female; Folic Acid; Genotype; Homocysteine; Humans; Ischemic Attack, Transient; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Vitamin B 12 | 1999 |
Posttranscriptional regulation of mammalian methionine synthase by B12.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Apoenzymes; Binding Sites; Cell Line; Cloning, Molecular; Enzyme Activation; Gene Expression Regulation, Enzymologic; Holoenzymes; Homocysteine; Humans; Kinetics; Protein Processing, Post-Translational; RNA, Messenger; Vitamin B 12 | 1999 |
Is pregnancy in diabetic women associated with folate deficiency?
Topics: Adult; Creatinine; Diet; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Glycated Hemoglobin; Homocysteine; Humans; Pregnancy; Pregnancy in Diabetics; Reference Values; Vitamin B 12 | 1999 |
Higher total homocysteine concentrations and lower folate concentrations in premenopausal black women than in premenopausal white women.
Topics: Adolescent; Adult; Black People; Coronary Disease; Feeding Behavior; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Premenopause; Reference Values; Surveys and Questionnaires; Vitamin B 12; White People | 1999 |
Prevalence of mild fasting hyperhomocysteinemia in renal transplant versus coronary artery disease patients after fortification of cereal grain flour with folic acid.
Topics: Coronary Disease; Fasting; Female; Flour; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Vitamin B 12 | 1999 |
Influence of 5,10-methylenetetrahydrofolate reductase gene polymorphism on plasma homocysteine concentration in patients with end-stage renal disease.
Topics: Cross-Sectional Studies; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Renal Dialysis; Vitamin B 12 | 1999 |
A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Amino Acid Substitution; Child; Child, Preschool; Deoxyribonucleases, Type II Site-Specific; DNA; Family Health; Female; Gene Frequency; Genetic Variation; Genotype; Homocysteine; Humans; Isoleucine; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Regression Analysis; Risk Factors; Spinal Dysraphism; Vitamin B 12 | 1999 |
Increased prevalence of methylenetetrahydrofolate reductase C677T variant in patients with inflammatory bowel disease, and its clinical implications.
Topics: Adolescent; Adult; Age Factors; Aged; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Inflammatory Bowel Diseases; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Prospective Studies; Vitamin B 12 | 1999 |
[Nutritional status and energy expenditure in elders of differing socioeconomic level].
Topics: Absorptiometry, Photon; Aged; Anthropometry; Body Composition; Calorimetry; Energy Metabolism; Female; Folic Acid; Homocysteine; Humans; Male; Micronutrients; Nutritional Status; Socioeconomic Factors; Urban Population; Vitamin B 12 | 1999 |
Homocysteine, vitamins and sex.
Topics: Folic Acid; Homocysteine; Humans; Pyridoxine; Sex Factors; Vascular Diseases; Vitamin B 12 | 1999 |
Homocysteine, vitamin status and risk of vascular disease; effects of gender and menopausal status. European COMAC Group.
Topics: Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Menopause; Pyridoxine; Risk Factors; Sex Factors; Vascular Diseases; Vitamin B 12 | 1999 |
Serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey (1991-1994): population reference ranges and contribution of vitamin status to high serum concentrations.
Topics: Adolescent; Adult; Child; Cross-Sectional Studies; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Linear Models; Male; Middle Aged; Nutritional Status; Reference Values; United States; Vitamin B 12; Vitamin B Complex | 1999 |
Turn of tide for oral vitamin B12 treatment.
Topics: Administration, Oral; Aged; Biological Availability; Biomarkers; England; Female; Homocysteine; Humans; Infusions, Intravenous; Methylmalonic Acid; Neural Tube Defects; Pregnancy; Pregnancy Complications; Sweden; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Molecular basis for methionine synthase reductase deficiency in patients belonging to the cblE complementation group of disorders in folate/cobalamin metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Megaloblastic; DNA Mutational Analysis; DNA, Complementary; Enzyme Activation; Ferredoxin-NADP Reductase; Folic Acid; Genes, Recessive; Genetic Complementation Test; Heteroduplex Analysis; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Mutation; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; RNA Splicing; Sequence Analysis, DNA; Vitamin B 12 | 1999 |
Schilling and protein-bound cobalamin absorption tests are poor instruments for diagnosing cobalamin malabsorption.
Topics: Adult; Atrophy; Duodenum; Female; Homocysteine; Humans; Intestinal Absorption; Male; Methylmalonic Acid; Reference Values; Reproducibility of Results; Schilling Test; Stomach; Sweden; Vitamin B 12; Vitamin B 12 Deficiency; Volunteers | 1997 |
A polymorphism of the methionine synthase gene: association with plasma folate, vitamin B12, homocyst(e)ine, and colorectal cancer risk.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Canada; Case-Control Studies; Colorectal Neoplasms; Folic Acid; Genotype; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk Factors; Surveys and Questionnaires; United States; Vitamin B 12; White People | 1999 |
Hyperhomocyst(e)inemia and the prevalence of atherosclerotic vascular disease in patients with end-stage renal disease.
Topics: Aged; Arteriosclerosis; Coronary Artery Disease; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Odds Ratio; Renal Dialysis; Retrospective Studies; Risk Factors; Sex Factors; Vitamin B 12 | 1999 |
Nonsyndromic orofacial clefts: association with maternal hyperhomocysteinemia.
Topics: Adult; Case-Control Studies; Child, Preschool; Cleft Lip; Cleft Palate; Erythrocytes; Fasting; Female; Folic Acid; Homocysteine; Humans; Infant; Maternal-Fetal Exchange; Methionine; Pregnancy; Pyridoxine; Risk Factors; Vitamin B 12 | 1999 |
Influence of folic acid, pyridoxal phosphate and cobalamin on plasma homocyst(e)ine levels and the susceptibility of low-density lipoprotein to ex-vivo oxidation.
Topics: Adult; Aged; Arteriosclerosis; Folic Acid; Homocysteine; Humans; Hypercholesterolemia; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Peripheral Vascular Diseases; Pyridoxal Phosphate; Risk Factors; Vitamin B 12 | 1999 |
Hyperhomocyst(e)inemia is associated with carotid atherosclerosis.
Topics: Age Factors; Body Mass Index; Carotid Artery Diseases; Carotid Artery, Common; Carotid Artery, Internal; Chromatography, High Pressure Liquid; Creatinine; Diabetes Complications; Female; Fluorescence; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; Logistic Models; Male; Middle Aged; Regression Analysis; Risk Factors; Sex Factors; Smoking; Tunica Intima; Tunica Media; Ultrasonography; Vitamin B 12 | 1999 |
Serum cobalamin, homocysteine, and methylmalonic acid concentrations in a multiethnic elderly population: ethnic and sex differences in cobalamin and metabolite abnormalities.
Topics: Aged; Analysis of Variance; Ethnicity; Female; Folic Acid; Homocysteine; Humans; Los Angeles; Male; Methylmalonic Acid; Middle Aged; Racial Groups; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Extracellular magnesium regulates effects of vitamin B6, B12 and folate on homocysteinemia-induced depletion of intracellular free magnesium ions in canine cerebral vascular smooth muscle cells: possible relationship to [Ca2+]i, atherogenesis and stroke.
Topics: Animals; Arteriosclerosis; Basilar Artery; Calcium; Cells, Cultured; Cerebral Arteries; Dogs; Folic Acid; Homocysteine; Hyperhomocysteinemia; Magnesium; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Pyridoxine; Signal Transduction; Stroke; Vitamin B 12; Vitamins | 1999 |
The effect of diet on plasma homocysteine concentrations in healthy male subjects.
Topics: Adult; Cross-Sectional Studies; Diet; Diet, Vegetarian; Fasting; Folic Acid; Homocysteine; Humans; Male; Meat; Methionine; Methylation; Middle Aged; Vitamin B 12 | 1999 |
[Gender differences in serum homocysteine levels and associated factors].
Topics: Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Sex Characteristics; Vitamin B 12 | 1999 |
Sustained reduction of hyperhomocysteinaemia with folic acid supplementation in predialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Prospective Studies; Pyridoxine; Renal Dialysis; Vitamin B 12 | 1999 |
Evaluation of low serum vitamin B(12) in the non-anaemic pregnant patient.
Topics: Adult; Erythrocyte Indices; Female; Gestational Age; Homocysteine; Humans; Methylmalonic Acid; Parity; Pregnancy; Pregnancy Complications; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Effect of short-term vitamin (folic acid, vitamins B6 and B12) administration on endothelial dysfunction induced by post-methionine load hyperhomocysteinemia.
Topics: Administration, Oral; Adult; Blood Flow Velocity; Drug Therapy, Combination; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Pyridoxine; Treatment Outcome; Vasodilation; Vitamin B 12 | 1999 |
Can reduced folic acid and vitamin B12 levels cause deficient DNA methylation producing mutations which initiate atherosclerosis?
Topics: Arteriosclerosis; DNA Methylation; Folic Acid; Homocysteine; Humans; Models, Biological; Mutation; Vitamin B 12 | 1999 |
Concentrations of plasma methylmalonic acid in 80-year-olds show only weak relation to psychological performance.
Topics: Aged; Aged, 80 and over; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Methylmalonic Acid; Psychological Tests; Vitamin B 12 | 1999 |
Identification of the zinc ligands in cobalamin-independent methionine synthase (MetE) from Escherichia coli.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Binding Sites; Chelating Agents; Escherichia coli; Homocysteine; Ligands; Molecular Sequence Data; Mutation; Sequence Alignment; Vitamin B 12; Zinc | 1999 |
The effect of estrogen replacement therapy on total plasma homocysteine in healthy postmenopausal women.
Topics: Adult; Estrogen Replacement Therapy; Folic Acid; Homocysteine; Humans; Linear Models; Lipids; Methionine; Middle Aged; Postmenopause; Pyridoxine; Reference Values; Time Factors; Vitamin B 12 | 2000 |
Coffee and homocysteine.
Topics: Coffee; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Randomized Controlled Trials as Topic; Vitamin B 12 | 2000 |
Methylenetetrahydrofolate reductase 677 C --> T polymorphism, plasma folate, vitamin B(12) concentrations, and risk of preeclampsia among black African women from Zimbabwe.
Topics: Adolescent; Adult; Alleles; Black People; Case-Control Studies; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Nutritional Physiological Phenomena; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Risk Factors; Vitamin B 12; Zimbabwe | 2000 |
Plasma homocysteine concentrations and risk of coronary heart disease in UK Indian Asian and European men.
Topics: Case-Control Studies; Coronary Disease; Europe; Fasting; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Risk Factors; United Kingdom; Vitamin B 12 | 2000 |
Low plasma folate in combination with the 677 C-->T methylenetetrahydrofolate reductase polymorphism is associated with increased risk of coronary artery disease in Koreans.
Topics: Adult; Aged; Asian People; Cardiac Catheterization; Coronary Disease; Female; Folic Acid; Gene Frequency; Homocysteine; Humans; Hyperhomocysteinemia; Korea; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors; Sex Factors; Vitamin B 12 | 2000 |
Association between total homocyst(e)ine and the likelihood for a history of acute myocardial infarction by race and ethnicity: Results from the Third National Health and Nutrition Examination Survey.
Topics: Age Distribution; Black People; Cholesterol; Comorbidity; Diabetes Mellitus; Educational Status; Female; Folic Acid; Homocysteine; Homocystine; Humans; Hypertension; Male; Mexico; Middle Aged; Multivariate Analysis; Myocardial Infarction; Nutrition Surveys; Odds Ratio; Prevalence; Risk Assessment; Sex Distribution; Smoking; United States; Vitamin B 12; White People | 2000 |
Homocysteine, folate, vitamin B12, and cardiovascular risk in Indians, Malays, and Chinese in Singapore.
Topics: Adult; Aged; Biomarkers; China; Coronary Disease; Cross-Sectional Studies; Disease Susceptibility; Female; Homocysteine; Humans; India; Malaysia; Male; Middle Aged; Sex Factors; Singapore; Vitamin B 12 | 2000 |
Effects of supplementation with folic acid and antioxidant vitamins on homocysteine levels and LDL oxidation in coronary patients.
Topics: Antioxidants; Ascorbic Acid; beta Carotene; Coronary Disease; Dietary Supplements; Folic Acid; Homocysteine; Humans; Lipid Peroxidation; Lipids; Lipoproteins, LDL; Vitamin B 12; Vitamin E; Vitamins | 2000 |
Cobalt-deficiency-induced hyperhomocysteinaemia and oxidative status of cattle.
Topics: Animals; Cattle; Cattle Diseases; Cobalt; Homocysteine; Hyperhomocysteinemia; Male; Oxidative Stress; Vitamin B 12 | 2000 |
[Hyperhomocysteinemia and arterial or venous thrombosis. Retrospective study of 75 cases].
Topics: Adult; Aged; Aged, 80 and over; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retrospective Studies; Risk Factors; Thrombosis; Vitamin B 12 | 2000 |
Plasma homocysteine levels in acute coronary syndromes.
Topics: Adult; Aged; Angina, Unstable; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Myocardial Infarction; Risk Factors; Vitamin B 12 | 1999 |
Homocysteine thiolactone is a positive effector of sigma(S) levels in Escherichia coli.
Topics: Bacterial Proteins; Culture Media; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Homocysteine; Methionine; Repressor Proteins; Sigma Factor; Vitamin B 12 | 2000 |
Plasma homocysteine levels in renal transplanted patients on cyclosporine or tacrolimus therapy: effect of treatment with folic acid.
Topics: Analysis of Variance; Case-Control Studies; Cholesterol; Creatinine; Cyclosporine; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Linear Models; Male; Middle Aged; Multivariate Analysis; Risk Factors; Tacrolimus; Triglycerides; Vitamin B 12 | 2000 |
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Phenobarbital; Phenytoin; Primidone; Treatment Outcome; Valproic Acid; Vitamin B 12 | 2000 |
Homocysteine, folate, vitamin B-12 and vitamin B-6 in patients receiving antiepileptic drug monotherapy.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Aged; Anticonvulsants; Drug Stability; Female; Folic Acid; Genotype; Homocysteine; Hot Temperature; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Osmolar Concentration; Oxidoreductases; Pyridoxine; Vitamin B 12 | 2000 |
Effect of chronic alcohol consumption on total plasma homocysteine level in rats.
Topics: Alcohol Drinking; Animals; Folic Acid; Hematinics; Homocysteine; Hyperhomocysteinemia; Male; Pyridoxine; Rats; Rats, Sprague-Dawley; Vitamin B 12 | 2000 |
The role of vitamin B12 in fasting hyperhomocysteinemia and its interaction with the homozygous C677T mutation of the methylenetetrahydrofolate reductase (MTHFR) gene. A case-control study of patients with early-onset thrombotic events.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Age of Onset; Aged; Amino Acid Substitution; Case-Control Studies; Fasting; Female; Folic Acid; Gene Frequency; Genetic Heterogeneity; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutritional Requirements; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Risk Factors; Sex Factors; Tetrahydrofolates; Thrombophilia; Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
[Lowering high levels of fasting total homocysteine with folic acid and vitamins B in patients with venous thromboembolism: relationship between response and the C677T methylenetetrahydrofolate reductase (MTHRF) genotype].
Topics: Adult; Electrophoresis; Female; Folic Acid; Gene Expression; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Pyridoxine; Recurrence; Thrombophlebitis; Vitamin B 12 | 2000 |
Spina bifida and common mutations at the homocysteine metabolism pathway.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alleles; Case-Control Studies; Cystathionine beta-Synthase; Female; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Risk; Spinal Dysraphism; Vitamin B 12 | 2000 |
Re: Pregnancy outcomes in celiac women.
Topics: Autoantibodies; Birth Weight; Celiac Disease; Congenital Abnormalities; Female; Folic Acid; Homocysteine; Humans; Muscle Fibers, Skeletal; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12 | 2000 |
[Correct information on vitamin B12?].
Topics: Advertising; Biomarkers; Drug Combinations; Drug Information Services; Homocysteine; Humans; Tablets; Vitamin B 12 | 2000 |
[B12 deficiency--an underestimated problem].
Topics: Administration, Oral; Advertising; Biomarkers; Drug Combinations; Drug Information Services; Homocysteine; Humans; Injections, Intramuscular; Tablets; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Homocysteine, vitamins B6, B12, folate, and risk of coronary artery disease in patients undergoing diagnostic coronary angiography.
Topics: Aged; Case-Control Studies; Coronary Angiography; Coronary Disease; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Pyridoxine; Risk Factors; Vitamin B 12 | 2000 |
Tissue factor pathway inhibitor levels in patients with homocystinuria.
Topics: Adult; Betaine; Biomarkers; Cystathionine beta-Synthase; Endothelium; Factor VII; Female; Fibrinolytic Agents; Heparin; Homocysteine; Homocystinuria; Homozygote; Humans; Lipoproteins; Male; Protein C; Pyridoxine; Serine Proteinase Inhibitors; Thrombomodulin; Thromboplastin; Vascular Diseases; Vitamin B 12 | 2000 |
Association between serum homocysteine, vitamin B12, folate and Thai coronary artery disease patients.
Topics: Aged; Analysis of Variance; Biomarkers; Case-Control Studies; Coronary Disease; Cross-Sectional Studies; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Male; Middle Aged; Pteroylpolyglutamic Acids; Reference Values; Sensitivity and Specificity; Thailand; Vitamin B 12 | 2000 |
Low serum folate but normal homocysteine levels in patients with atherosclerotic vascular disease and matched healthy controls.
Topics: Aged; Arteriosclerosis; Cholesterol; Chromatography, High Pressure Liquid; Coronary Disease; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipoproteins, HDL; Male; Middle Aged; Risk Factors; Triglycerides; Vitamin B 12; Vitamin E | 2000 |
Etiology and diagnostic evaluation of macrocytosis.
Topics: Adult; Aged; Alcohol Drinking; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow Diseases; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; L-Lactate Dehydrogenase; Leukocyte Count; Liver Diseases; Liver Diseases, Alcoholic; Male; Methylmalonic Acid; Middle Aged; Platelet Count; Predictive Value of Tests; Prospective Studies; Reticulocyte Count; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Homocysteine and heart disease in Indian Asians.
Topics: Coronary Disease; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; India; Risk Factors; United Kingdom; Vitamin B 12 | 2000 |
Homocysteine and heart disease in Indian Asians.
Topics: Coronary Disease; Folic Acid; Folic Acid Deficiency; Fructose; Homocysteine; Humans; Hyperhomocysteinemia; India; Malabsorption Syndromes; United Kingdom; Vitamin B 12 | 2000 |
Inhibition of vitamin B12 metabolism by OH-cobalamin c-lactam in rat oligodendrocytes in culture: a model for studying neuropathy due to vitamin B12 deficiency.
Topics: Animals; Animals, Newborn; Cells, Cultured; Culture Media, Conditioned; Homocysteine; Humans; Methylmalonic Acid; Oligodendroglia; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Plasma homocysteine and its determinants in diabetic retinopathy.
Topics: Biomarkers; Blood Pressure; Creatinine; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Folic Acid; Gene Frequency; Homocysteine; Homozygote; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Vitamin B 12 | 2000 |
[PS on homocysteine as a risk factor of cardiovascular disease].
Topics: Biomarkers; Homocysteine; Humans; Myocardial Infarction; Vitamin B 12 | 2000 |
Impaired glucose tolerance (IGT) is not associated with disturbed homocysteine metabolism.
Topics: Blood Glucose; Cardiovascular Diseases; Creatinine; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Fasting; Folic Acid; Homocysteine; Humans; Insulin; Male; Methionine; Middle Aged; Proinsulin; Risk Factors; Time Factors; Vitamin B 12 | 2000 |
[TrioBe--the Medical Products Agency should re-evaluate the information text in the Fass!].
Topics: Catalogs, Drug as Topic; Drug Combinations; Drug Information Services; Folic Acid; Homocysteine; Humans; Pyridoxine; Risk Factors; Sweden; Vitamin B 12 | 2000 |
Total homocysteine and estrogen status indicators in the Third National Health and Nutrition Examination Survey.
Topics: Adolescent; Adult; Aged; Aging; Contraceptives, Oral, Hormonal; Creatinine; Estrogens; Female; Folic Acid; Health Surveys; Homocysteine; Hormone Replacement Therapy; Humans; Male; Middle Aged; United States; Vitamin B 12 | 2000 |
Case-control study of plasma folate, homocysteine, vitamin B(12), and cysteine as markers of cervical dysplasia.
Topics: Adult; Alcohol Drinking; Case-Control Studies; Contraceptives, Oral; Cysteine; DNA, Viral; Female; Folic Acid; Gravidity; Homocysteine; Humans; Middle Aged; Papillomaviridae; Papillomavirus Infections; Regression Analysis; Risk Factors; Tumor Virus Infections; Uterine Cervical Dysplasia; Vitamin B 12 | 2000 |
The risk of cervical cancer in relation to serum concentrations of folate, vitamin B12, and homocysteine.
Topics: Adult; Case-Control Studies; DNA Repair; Female; Folic Acid; Homocysteine; Humans; Odds Ratio; Risk Assessment; Uterine Cervical Neoplasms; Vitamin B 12 | 2000 |
Increased plasma homocysteine is an independent predictor of new coronary events in older persons.
Topics: Aged; Aged, 80 and over; Coronary Disease; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Myocardial Infarction; Recurrence; Risk Factors; Vitamin B 12 | 2000 |
Folate and vitamin B12 status of adolescent girls in northern Nigeria.
Topics: Adolescent; Biomarkers; Child; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Incidence; Nigeria; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Assessment of vitamin B-12, folate, and vitamin B-6 status and relation to sulfur amino acid metabolism in neonates.
Topics: Amino Acids; Breast Feeding; Cross-Sectional Studies; Cysteine; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Infant Food; Infant, Newborn; Male; Pyridoxine; Sulfur; Vitamin B 12 | 2000 |
Insulin is an independent correlate of plasma homocysteine levels in obese children and adolescents.
Topics: Adolescent; Blood Pressure; Child; Child, Preschool; Cholesterol; Coronary Disease; Female; Folic Acid; Homocysteine; Humans; Insulin; Lipoproteins; Male; Methylenetetrahydrofolate Reductase (NADPH2); Obesity; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Regression Analysis; Risk Factors; Triglycerides; Vitamin B 12 | 2000 |
Effect of MTHFR 1298A-->C and MTHFR 677C-->T genotypes on total homocysteine, folate, and vitamin B(12) plasma concentrations in kdiney graft recipients.
Topics: Adult; Aged; Alleles; Base Sequence; Female; Folic Acid; Forecasting; Gene Frequency; Genotype; Homocysteine; Humans; Kidney Transplantation; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Osmolar Concentration; Oxidoreductases Acting on CH-NH Group Donors; Vitamin B 12 | 2000 |
A common polymorphism in methionine synthase reductase increases risk of premature coronary artery disease.
Topics: Age Factors; Base Sequence; Coronary Disease; Data Interpretation, Statistical; Female; Ferredoxin-NADP Reductase; Flavoproteins; Folic Acid; Genotype; Homocysteine; Humans; Male; Middle Aged; Molecular Sequence Data; Multivariate Analysis; Polymerase Chain Reaction; Polymorphism, Genetic; Regression Analysis; Risk; Sex Factors; Vitamin B 12 | 2000 |
An Ontario-wide study of vitamin B12, serum folate, and red cell folate levels in relation to plasma homocysteine: is a preventable public health issue on the rise?.
Topics: Age Factors; Biomarkers; Creatinine; Cross-Sectional Studies; Dietary Supplements; Erythrocyte Indices; Erythrocytes; Female; Folic Acid Deficiency; Hemoglobins; Homocysteine; Humans; Male; Middle Aged; Ontario; Population Surveillance; Retrospective Studies; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Homocysteine elevation in sickle cell disease.
Topics: Adolescent; Adult; Case-Control Studies; Dietary Supplements; Female; Folic Acid; Hemoglobin SC Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutritional Requirements; Pilot Projects; Vitamin B 12 | 2000 |
The influence of age, sex, vitamin B(12), folate levels and methylenetetrahydrofolate reductase C677T genetic mutations on plasma homocysteine in the Chinese population.
Topics: Age Factors; Aged; China; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Sex Factors; Thromboembolism; Vitamin B 12 | 2000 |
Moderately low vitamin B12 does not compromise transmethylation in adults on a free diet: implications for assessment of vitamin B12 status.
Topics: Analysis of Variance; Creatine; Dietary Proteins; Homocysteine; Humans; Methionine; Methylation; Reference Values; Statistics as Topic; Vitamin B 12 | 2000 |
[Homocysteine and its metabolites in chronic renal insufficiency and the effect of a vitamin replacement].
Topics: Adult; Aged; Arteriosclerosis; Cysteine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methionine; Middle Aged; Pyridoxine; Renal Dialysis; Severity of Illness Index; Vitamin B 12; Vitamin B Complex | 2000 |
Plasma and serum total homocysteine concentrations in paediatric patients, evaluated by high-performance liquid chromatography with fluorescence.
Topics: Child; Chromatography, High Pressure Liquid; Female; Fluorescence; Folic Acid; Homocysteine; Humans; Male; Reference Values; Vitamin B 12 | 2000 |
[Evaluation of analytic test methods. Stomach-intestines status is the best diagnostic method in suspected vitamin B12 deficiency].
Topics: Biomarkers; Gastric Mucosa; Gastritis, Atrophic; Gastrointestinal Diseases; Gastroscopy; Homocysteine; Humans; Intestinal Mucosa; Methylmalonic Acid; Pepsinogen C; Practice Guidelines as Topic; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Age-related hearing impairment and B vitamin status.
Topics: Acoustic Impedance Tests; Age Factors; Aged; Aged, 80 and over; Aging; Audiometry, Pure-Tone; Audiometry, Speech; Female; Folic Acid; Homocysteine; Humans; Male; Presbycusis; Severity of Illness Index; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Homocysteine levels in vegetarians versus omnivores.
Topics: Adult; Aged; Diet; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Slovakia; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Evaluation of indicators of cobalamin deficiency defined as cobalamin-induced reduction in increased serum methylmalonic acid.
Topics: Adolescent; Aged; Aged, 80 and over; Female; Folic Acid; Gastroscopy; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Oxidation-Reduction; Regression Analysis; ROC Curve; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Determinants of plasma total homocysteine levels in Korean chronic renal transplant recipients.
Topics: Adult; Aged; Cardiovascular Diseases; Creatinine; Cross-Sectional Studies; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Transplantation; Korea; Male; Middle Aged; Prevalence; Pyridoxal Phosphate; Serum Albumin; Vitamin B 12 | 2000 |
Nitric oxide in neonates.
Topics: Administration, Inhalation; Folic Acid; Homocysteine; Humans; Infant, Newborn; Lung Diseases, Obstructive; Nitric Oxide; Spinal Cord Diseases; Vitamin B 12 | 2000 |
[Demyelinization and vitamin B12].
Topics: Demyelinating Diseases; Homocysteine; Humans; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Homocysteine concentration in primary and systemic sclerosis associated Raynaud's phenomenon.
Topics: Adult; Aged; Female; Folic Acid; Genotype; Homocysteine; Homozygote; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Osmolar Concentration; Oxidoreductases Acting on CH-NH Group Donors; Raynaud Disease; Scleroderma, Systemic; Vitamin B 12; von Willebrand Factor | 2000 |
Vitamin B-12 deficiency and hyperhomocysteinemia are partly ameliorated by cobalt and nickel supplementation in pigs.
Topics: Animal Feed; Animals; Cobalt; Copper; Dietary Supplements; Disease Models, Animal; Female; Folic Acid; Homocysteine; Hyperhomocysteinemia; Iron; Liver; Male; Nickel; Swine; Trace Elements; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Serum total homocysteine concentration is related to self-reported heart attack or stroke history among men and women in the NHANES III.
Topics: Adult; Age Factors; Aged; Female; Folic Acid; Heart Arrest; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutrition Surveys; Risk Factors; Self Disclosure; Sex Factors; Stroke; Vitamin B 12 | 2000 |
Risk factors for cardiovascular disease in renal transplant recipients: new insights.
Topics: Autoantibodies; Biomarkers; Cardiovascular Diseases; Female; Folic Acid; Glomerular Filtration Rate; Hemostasis; Homocysteine; Humans; Kidney Transplantation; Lipoprotein(a); Male; Middle Aged; Plasminogen Activator Inhibitor 1; Postoperative Complications; Reference Values; Risk Factors; Vitamin B 12 | 2000 |
Homocysteine and thiol metabolites in vitamin B12 deficiency.
Topics: Aged; Cysteine; Dehydroepiandrosterone Sulfate; Female; Glutathione Peroxidase; Homocysteine; Humans; Male; Middle Aged; Sulfhydryl Compounds; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Plasma homocysteine and severity of thoracic aortic atherosclerosis.
Topics: Adult; Aged; Aged, 80 and over; Aorta, Thoracic; Aortic Diseases; Arteriosclerosis; Biomarkers; Cholesterol; Coronary Artery Disease; Cross-Sectional Studies; Echocardiography, Transesophageal; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Risk Factors; Vitamin B 12 | 2000 |
Blood homocysteine and vitamin B levels are not associated with cognitive skills in healthy normally ageing subjects.
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Cognition; Dementia; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Vitamin B 12 | 2000 |
Hyperhomocysteinemia in renal transplant recipients with cyclosporine.
Topics: Cyclosporine; Erythrocytes; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Middle Aged; Reference Values; Vitamin B 12 | 2000 |
Role of homocysteine, cystathionine and methylmalonic acid measurement for diagnosis of vitamin deficiency in high-aged subjects.
Topics: Adult; Aged; Cystathionine; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Kidney; Male; Methylmalonic Acid; Middle Aged; Models, Chemical; Pyridoxine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2000 |
Hyperhomocysteinemia in type 2 diabetes: relationship to macroangiopathy, nephropathy, and insulin resistance.
Topics: Aged; Cohort Studies; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Female; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Logistic Models; Male; Metabolic Clearance Rate; Metformin; Middle Aged; Vitamin B 12 | 2000 |
Hyperhomocysteinemia in renal transplantation: preliminary results.
Topics: Adult; Aged; Cross-Sectional Studies; Drug Therapy, Combination; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Prevalence; Pyridoxine; Time Factors; Vitamin B 12 | 2000 |
Long-term reduction of plasma homocysteine levels by super-flux dialyzers in hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Pyridoxine; Renal Dialysis; Serum Albumin; Time Factors; Vitamin B 12 | 2001 |
Increased levels of homocysteine in patients with Crohn's disease are related to folate levels.
Topics: Adult; Aged; Anti-Inflammatory Agents; Budesonide; Case-Control Studies; Crohn Disease; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Prednisone; Risk Factors; Thromboembolism; Time Factors; Vitamin B 12 | 2000 |
Prevention of vitamin B-12 deficiency in old age.
Topics: Aged; Cardiovascular Diseases; Dietary Supplements; Folic Acid; Food, Fortified; Homocysteine; Humans; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Genetic, dietary, and other lifestyle determinants of plasma homocysteine concentrations in middle-aged and older Chinese men and women in Singapore.
Topics: Aged; Aging; Asian People; Cohort Studies; Exercise; Female; Folic Acid; Genotype; Homocysteine; Humans; Interviews as Topic; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Prospective Studies; Pyridoxine; Risk Factors; Sex Factors; Singapore; Smoking; Vascular Diseases; Vitamin B 12 | 2001 |
Transcobalamin codon 259 polymorphism in HT-29 and Caco-2 cells and in Caucasians: relation to transcobalamin and homocysteine concentration in blood.
Topics: Adult; Aged; Amino Acid Substitution; Caco-2 Cells; Codon; DNA, Complementary; Female; Folic Acid; France; Gene Expression Regulation, Neoplastic; Gene Frequency; Genotype; Homocysteine; HT29 Cells; Humans; Male; Middle Aged; Neoplasm Proteins; Phenotype; Polymorphism, Genetic; Transcobalamins; Transcription, Genetic; Transfection; Vitamin B 12; White People | 2001 |
Elevated plasma homocysteine levels in centenarians are not associated with cognitive impairment.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Dementia; Dementia, Vascular; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Male; Pyridoxine; Reference Values; Vitamin B 12 | 2000 |
Is there a role of cyclosporine A on total homocysteine export from human renal proximal tubular epithelial cells?
Topics: Biological Transport, Active; Cells, Cultured; Cyclosporine; Epithelial Cells; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Kidney Tubules, Proximal; Methionine; Pyridoxine; Vitamin B 12 | 2001 |
Low seminal plasma folate concentrations are associated with low sperm density and count in male smokers and nonsmokers.
Topics: Adult; Diet; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Semen; Smoking; Sperm Count; Spermatozoa; Tetrahydrofolates; Vitamin B 12; Vitamins | 2001 |
Evaluation of the cobalt requirement of beef cattle based on vitamin B12, folate, homocysteine and methylmalonic acid.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Cobalt; Homocysteine; Liver; Male; Methylmalonic Acid; Nutritional Requirements; Radioimmunoassay; Vitamin B 12 | 2000 |
Relationships between homocysteine, folate and vitamin B12 levels with the methylenetetrahydrofolate reductase polymorphism, in Indians from Western Venezuela.
Topics: Analysis of Variance; Folic Acid; Genotype; Homocysteine; Humans; Indians, South American; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Venezuela; Vitamin B 12; Vitamin B Complex | 2001 |
Gene-environment and gene-gene interaction in the determination of plasma homocysteine levels in healthy middle-aged men.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Analysis of Variance; Cystathionine beta-Synthase; Environmental Exposure; Environmental Pollution; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutritional Status; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prospective Studies; Smoking; Vitamin B 12 | 2001 |
Determinants of changes in plasma homocysteine in hyperthyroidism and hypothyroidism.
Topics: Adult; Age Factors; Aged; Analysis of Variance; Biomarkers; Cardiovascular Diseases; Creatinine; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperthyroidism; Hypothyroidism; Linear Models; Male; Metabolic Clearance Rate; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Polymorphism, Genetic; Prospective Studies; Risk Factors; Sex Factors; Smoking; Thyroid Function Tests; Thyroxine; Vitamin B 12 | 2001 |
Traditional and alternative nutrition--levels of homocysteine and lipid parameters in adults.
Topics: Adult; Aged; Arteriosclerosis; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dairy Products; Diet, Vegetarian; Eggs; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Methionine; Middle Aged; Nutritional Physiological Phenomena; Reference Values; Risk Factors; Vitamin B 12 | 2000 |
Plasma folate, vitamin B(12), and homocyst(e)ine concentrations in preeclamptic and normotensive Peruvian women.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Odds Ratio; Peru; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Surveys and Questionnaires; Vitamin B 12 | 2001 |
Mutations in the gene for methylenetetrahydrofolate reductase, homocysteine levels, and vitamin status in women with a history of preeclampsia.
Topics: Birth Weight; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Primers; Electrophoresis, Polyacrylamide Gel; Female; Folic Acid; Genotype; Gestational Age; HELLP Syndrome; Homocysteine; Humans; Infant, Newborn; Linear Models; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Polymerase Chain Reaction; Pre-Eclampsia; Pregnancy; Radioimmunoassay; Regression Analysis; Vitamin B 12 | 2001 |
Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Caffeine; Cohort Studies; Creatinine; Dietary Supplements; Fasting; Female; Folic Acid; Homocysteine; Humans; Hypertension; Kidney; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Pyridoxine; Riboflavin; Sex Factors; Smoking; Vitamin B 12 | 2001 |
Association of folate intake and serum homocysteine in elderly persons according to vitamin supplementation and alcohol use.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Coffee; Cross-Sectional Studies; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Life Style; Linear Models; Male; Methylmalonic Acid; Risk Factors; Smoking; Tea; Vascular Diseases; Vitamin B 12 | 2001 |
Mild hyperhomocyst(e)inemia: a possible risk factor for cervical artery dissection.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiography; Carotid Artery, Internal, Dissection; Comorbidity; Disease Susceptibility; Female; Folic Acid; Genotype; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Risk Factors; Vertebral Artery Dissection; Vitamin B 12 | 2001 |
[Plasma homocysteine levels in hyperinsulinemic patients].
Topics: Adult; Blood Glucose; Cohort Studies; Female; Folic Acid; Glucose Tolerance Test; Homocysteine; Humans; Hyperinsulinism; Male; Middle Aged; Severity of Illness Index; Sex Factors; Vitamin B 12 | 2001 |
The effect of the C677T and A1298C polymorphisms in the methylenetetrahydrofolate reductase gene on homocysteine levels in elderly men and women from the British regional heart study.
Topics: Aged; Aging; Alleles; Demography; Female; Folic Acid; Gene Frequency; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Regression Analysis; Sex Characteristics; Vitamin B 12 | 2001 |
Reduced vitamin B12 binding by transcobalamin II increases the risk of neural tube defects.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Electrophoresis, Agar Gel; Female; Homocysteine; Humans; Middle Aged; Neural Tube Defects; Polymerase Chain Reaction; Polymorphism, Genetic; Pregnancy; Risk Factors; Statistics as Topic; Transcobalamins; Vitamin B 12 | 2001 |
Racial variation in fasting and random homocysteine levels.
Topics: Black People; Blood Urea Nitrogen; Body Mass Index; Creatinine; Fasting; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; New York City; Personnel, Hospital; Random Allocation; Reference Values; Time Factors; Vitamin B 12; White People | 2001 |
Homocysteine, folate, vitamin B12, and transcobalamins in patients undergoing successive hypo- and hyperthyroid states.
Topics: Folic Acid; Homocysteine; Humans; Hyperthyroidism; Hypothyroidism; Transcobalamins; Vitamin B 12 | 2001 |
Plasma homocysteine and microvascular complications in type 1 diabetes.
Topics: Adult; Albuminuria; Case-Control Studies; Creatinine; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Vitamin B 12 | 2000 |
Quantitation of rate enhancements attained by the binding of cobalamin to methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Binding Sites; Catalysis; Enzyme Activation; Escherichia coli; Genetic Vectors; Homocysteine; Kinetics; Methylation; Mutagenesis, Insertional; Peptide Fragments; Recombinant Proteins; Substrate Specificity; Vitamin B 12 | 2001 |
Relation between homocysteinaemia and diabetic neuropathy in patients with Type 2 diabetes mellitus.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Blood Pressure; Creatinine; Cystatin C; Cystatins; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Pyridoxine; Vitamin B 12 | 2001 |
High cysteine levels in renal transplant recipients: relationship with hyperhomocysteinemia and 5,10-MTHFR polymorphism.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Cysteine; Female; Folic Acid; Genotype; Homocysteine; Humans; Kidney Transplantation; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases; Plasminogen Activator Inhibitor 1; Point Mutation; Polymorphism, Genetic; Pyridoxine; Vitamin B 12 | 2001 |
Homocysteine, vitamin B12, serum and erythrocyte folate in peritoneal dialysis patients.
Topics: Aged; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Peritoneal Dialysis; Vitamin B 12 | 2001 |
[Study of cobalamin deficiency in gastrectomized and aged subjects].
Topics: Age Factors; Aged; Creatinine; Data Interpretation, Statistical; Gastrectomy; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Renal insufficiency, vitamin B(12) status, and population attributable risk for mild hyperhomocysteinemia among coronary artery disease patients in the era of folic acid-fortified cereal grain flour.
Topics: Adult; Aged; Coronary Artery Disease; Coronary Disease; Creatinine; Edible Grain; Female; Flour; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Insufficiency; Risk Factors; Vitamin B 12 | 2001 |
Homocysteine--an innocent bystander in vascular disease?
Topics: Arteriosclerosis; Biomarkers; Endothelium, Vascular; Homocysteine; Humans; Pyridoxine; Risk Factors; Vitamin B 12 | 2001 |
Serum cobalamin, folate, methylmalonic acid and total homocysteine as vitamin B12 and folate tissue deficiency markers amongst elderly Swedes--a population-based study.
Topics: Age Factors; Aged; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Population Surveillance; Sex Factors; Sweden; Vitamin B 12; Vitamins | 2001 |
Influence of vitamin-optimized plasma homocysteine cutoff values on the prevalence of hyperhomocysteinemia in healthy adults.
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Pyridoxine; Vitamin B 12; Vitamins | 2001 |
Total homocysteine, vitamin B(12), and total antioxidant status in vegetarians.
Topics: Adult; Antioxidants; Diet, Vegetarian; Female; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations.
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Betaine; Betaine-Homocysteine S-Methyltransferase; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methyltransferases; Middle Aged; Peritoneal Dialysis; Predictive Value of Tests; Pyridoxine; Renal Dialysis; Sarcosine; Uremia; Vitamin B 12; Zinc | 2001 |
Plasma total cysteine as a risk factor for vascular disease: The European Concerted Action Project.
Topics: Adult; Case-Control Studies; Creatinine; Cysteine; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Pyridoxine; Risk Factors; Vascular Diseases; Vitamin B 12 | 2001 |
Reduced total plasma homocyst(e)ine in children and adolescents with type 1 diabetes.
Topics: Adolescent; Child; Creatinine; Diabetes Mellitus, Type 1; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Homocystine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Vitamin B 12 | 2001 |
Homocysteine metabolism in children with Down syndrome: in vitro modulation.
Topics: Adenosine; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cystathionine beta-Synthase; Cysteine; DNA Methylation; Down Syndrome; Glutathione; Homocysteine; Humans; Leucovorin; Lymphocytes; Methionine; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Superoxide Dismutase; Thymidine; Vitamin B 12 | 2001 |
Factors explaining the difference of total homocysteine between men and women in the European Investigation Into Cancer and Nutrition Potsdam study.
Topics: Adult; Age Factors; Aged; Analysis of Variance; Body Mass Index; Cohort Studies; Female; Folic Acid; Germany; Gonadal Steroid Hormones; Homocysteine; Humans; Linear Models; Male; Middle Aged; Neoplasms; Nutritional Physiological Phenomena; Sex Factors; Vitamin B 12 | 2001 |
Low circulating vitamin B(6) is associated with elevation of the inflammation marker C-reactive protein independently of plasma homocysteine levels.
Topics: Aged; Aged, 80 and over; C-Reactive Protein; Cohort Studies; Creatinine; Diet; Female; Folic Acid; Homocysteine; Humans; Inflammation; Logistic Models; Male; Massachusetts; Pyridoxal Phosphate; Pyridoxine; Risk Factors; Serum Albumin; Vitamin B 12 | 2001 |
Elevated homocysteine levels with weight loss after Lap-Band surgery: higher folate and vitamin B12 levels required to maintain homocysteine level.
Topics: Adult; Case-Control Studies; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Male; Obesity, Morbid; Vitamin B 12; Weight Loss | 2001 |
Effect of feeding on circulating micronutrient concentrations in the Burmese python (Python molurus).
Topics: Animals; Blood; Boidae; Copper; Erythrocytes; Fasting; Feeding Behavior; Folic Acid; gamma-Glutamyl Hydrolase; Hematocrit; Homocysteine; Micronutrients; Pyridoxal Phosphate; Vitamin B 12; Zinc | 2001 |
Association of two MTHFR polymorphisms with total homocysteine plasma levels in dialysis patients.
Topics: Adult; Aged; Dialysis; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Kidney Failure, Chronic; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Peritoneal Dialysis; Polymorphism, Genetic; Renal Dialysis; Vitamin B 12 | 2001 |
Relationships between homocysteine and related amino acids in chronic hemodialysis patients.
Topics: Amino Acids; Erythrocytes; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Renal Dialysis; Vitamin B 12 | 2001 |
Homocysteine concentrations in a German cohort of 500 individuals: reference ranges and determinants of plasma levels in healthy children and their parents.
Topics: Adolescent; Adult; Age Factors; Body Weight; Child; Creatine; Creatinine; Female; Folic Acid; Germany; Homocysteine; Humans; Male; Middle Aged; Prospective Studies; Reference Values; Sex Factors; Vitamin B 12 | 2001 |
Elevated serum homocysteine levels and increased risk of invasive cervical cancer in US women.
Topics: Adult; Alabama; Case-Control Studies; Chromatography, High Pressure Liquid; Colorado; Enzyme-Linked Immunosorbent Assay; Female; Florida; Homocysteine; Humans; Illinois; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Odds Ratio; Papillomaviridae; Papillomavirus Infections; Pennsylvania; Predictive Value of Tests; Regression Analysis; Risk Assessment; Risk Factors; Tumor Virus Infections; Uterine Cervical Neoplasms; Vitamin B 12; Vitamin B 6 | 2001 |
Hyperhomocysteinemia in dementia.
Topics: Aged; Alzheimer Disease; Cognition Disorders; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mental Status Schedule; Pilot Projects; Reference Values; Regression Analysis; Risk Factors; Vitamin B 12 | 2000 |
A population study of the influence of beer consumption on folate and homocysteine concentrations.
Topics: Adult; Aged; Alcohol Drinking; Beer; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Czech Republic; Female; Fluorescence; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12 | 2001 |
Hyperhomocysteinemia and inflammatory bowel disease: prevalence and predictors in a cross-sectional study.
Topics: Adult; Cohort Studies; Cross-Sectional Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Models, Chemical; Prevalence; Risk Factors; Vitamin B 12 | 2001 |
Terminal ileum resection is associated with higher plasma homocysteine levels in Crohn's disease.
Topics: Adult; Blood Sedimentation; Creatinine; Crohn Disease; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Ileum; Male; Thrombophilia; Vitamin B 12 | 2001 |
Hyperhomocysteinemia and elevated methylmalonic acid indicate a high prevalence of cobalamin deficiency in Asian Indians.
Topics: Adult; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylmalonic Acid; Middle Aged; Prevalence; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Fasting plasma homocysteine levels in the insulin resistance syndrome: the Framingham offspring study.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Albuminuria; Blood Glucose; Coronary Disease; Creatinine; Fasting; Female; Folic Acid; Glucose Tolerance Test; Homocysteine; Humans; Insulin; Insulin Resistance; Male; Massachusetts; Middle Aged; Risk Factors; Sex Factors; Vitamin B 12 | 2001 |
Shifts in B12 opinions in primary health care of Sweden.
Topics: Attitude of Health Personnel; Biomarkers; Clinical Competence; Decision Making; Homocysteine; Humans; Methylmalonic Acid; Physicians, Family; Primary Health Care; Surveys and Questionnaires; Sweden; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
[Effect of vitamin B6, B12 and folic acid levels on basal blood homocysteine values and after methionine load].
Topics: Folic Acid; Homocysteine; Humans; Methionine; Middle Aged; Vitamin B 12; Vitamin B 6 | 2001 |
A statement of homocyst(e)ine and cardiovascular disease.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Pyridoxine; Risk Factors; Vitamin B 12 | 2001 |
[Plasma homocysteine levels in patients with ischemic heart disease].
Topics: Aged; Drug Administration Schedule; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Ischemia; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors; Vitamin B 12; Vitamin B 6 | 2001 |
The effect of polymorphisms of MTHER gene and vitamin B on hyperhomocysteinemia.
Topics: Aged; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymorphism, Restriction Fragment Length; Vitamin B 12 | 2001 |
Assessment of nutritional folate status and selected vitamin status of women of childbearing age.
Topics: Adolescent; Adult; Ascorbic Acid; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Nutrition Assessment; Nutrition Disorders; Nutritional Status; Poland; Seroepidemiologic Studies; Vitamin A; Vitamin B 12; Vitamin E; Vitamins | 2001 |
Homocysteine, vitamins and gene mutations in peripheral arterial disease.
Topics: Adult; Aged; Arterial Occlusive Diseases; Case-Control Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Peripheral Vascular Diseases; Vitamin B 12 | 2001 |
One-carbon metabolism and other biochemical correlates of cognitive impairment as visualized by principal component analysis.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Atrophy; Brain; Cognition Disorders; Dementia, Vascular; Diagnosis, Differential; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Reference Values; Severity of Illness Index; tau Proteins; Vitamin B 12 | 2001 |
Homocysteine, HIV, and heart disease.
Topics: Diet; Folic Acid; Heart Diseases; HIV Infections; Homocysteine; Humans; Vitamin B 12 | 2001 |
Association between erythrocyte mean corpuscular volume and peripheral arterial disease in male subjects: a case control study.
Topics: Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Erythrocyte Indices; gamma-Glutamyltransferase; Homocysteine; Humans; Male; Middle Aged; Regression Analysis; Smoking; Vitamin B 12 | 2001 |
The relationship among homocysteine, creatinine clearance, and albuminuria in patients with type 2 diabetes.
Topics: Aged; Albuminuria; Creatinine; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Male; Metabolic Clearance Rate; Middle Aged; Regression Analysis; Vitamin B 12 | 2001 |
COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk.
Topics: Breast Neoplasms; Case-Control Studies; Catechol O-Methyltransferase; Cysteine; Estrogens, Catechol; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylation; Micronutrients; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyridoxal Phosphate; Risk Factors; S-Adenosylmethionine; Vitamin B 12 | 2001 |
Plasma total homocysteine levels and the C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene: a study in an Italian population with dementia.
Topics: Aged; Alanine; Dementia; Female; Folic Acid; Homocysteine; Humans; Italy; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Valine; Vitamin B 12 | 2001 |
Is hyperhomocysteinemia due to the oxidative depletion of folate rather than to insufficient dietary intake?
Topics: Dementia, Vascular; Diet; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological; Models, Chemical; Neopterin; Oxidative Stress; Oxygen; Vascular Diseases; Vitamin B 12 | 2001 |
Genetic defects as important factors for moderate hyperhomocysteinemia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Age Factors; Aged; Aged, 80 and over; Cystathionine; DNA Mutational Analysis; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Protein Binding; Risk Factors; Sex Factors; Vitamin B 12; Vitamin B 6 | 2001 |
Homocysteine in cerebrovascular disease: an independent risk factor for subcortical vascular encephalopathy.
Topics: Aged; Arteries; Case-Control Studies; Cerebrovascular Disorders; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Risk Factors; Vitamin B 12; Vitamin B 6 | 2001 |
Does a single vitamin B-supplementation induce functional vitamin B-deficiency?
Topics: Adult; Cystathionine; Cysteine; Dietary Supplements; Folic Acid; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Methionine; Methylmalonic Acid; Middle Aged; Models, Biological; Pilot Projects; Time Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2001 |
Are children with cystic fibrosis who are treated with a proton-pump inhibitor at risk for vitamin B(12) deficiency?
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Case-Control Studies; Child; Child, Preschool; Cystic Fibrosis; Enzyme Inhibitors; Female; Homocysteine; Humans; Lansoprazole; Male; Omeprazole; Proton Pump Inhibitors; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Homocysteine and methylmalonic acid levels in pregnant Nepali women. Should cobalamin supplementation be considered?
Topics: Adolescent; Adult; Biomarkers; Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Nepal; Nutritional Status; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Hyperhomocysteinemia and hyperlipidemia in coronary heart disease.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Aged; Coronary Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases; Point Mutation; Risk Factors; Vitamin B 12 | 1999 |
Antiepileptic drugs as independent predictors of plasma total homocysteine levels.
Topics: Adult; Amino Acid Substitution; Anticonvulsants; Cholesterol; Cholesterol, HDL; Confidence Intervals; Cysteine; Epilepsy; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Mutation; Predictive Value of Tests; Prevalence; Statistics, Nonparametric; Threonine; Triglycerides; Vitamin B 12 | 2001 |
Determinants of increased plasma homocysteine in 221 stable liver transplant patients.
Topics: Comorbidity; Cyclosporine; Female; Folic Acid; Homocysteine; Humans; Immunosuppressive Agents; Life Style; Liver Transplantation; Male; Prevalence; Risk Factors; Tacrolimus; Vitamin B 12 | 2001 |
Mild hyperhomocysteinemia is not associated with cardiac allograft coronary disease.
Topics: Adult; Aged; Coronary Angiography; Coronary Disease; Creatinine; Cross-Sectional Studies; Female; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Vitamin B 12; Vitamin B 6 | 2001 |
Increased prevalence of combined MTR and MTHFR genotypes among individuals with severely elevated total homocysteine plasma levels.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; DNA; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Kidney Diseases; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Peritoneal Dialysis; Point Mutation; Polymorphism, Restriction Fragment Length; Renal Dialysis; Vitamin B 12 | 2001 |
Proteinuria and plasma total homocysteine levels in chronic renal disease patients with a normal range serum creatinine: critical impact of true glomerular filtration rate.
Topics: Adult; Aged; Chronic Disease; Creatinine; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Kidney; Kidney Diseases; Male; Middle Aged; Proteinuria; Pyridoxal Phosphate; Serum Albumin; Vitamin B 12 | 2001 |
Low plasma levels of vitamin B(6) are independently associated with a heightened risk of deep-vein thrombosis.
Topics: Adolescent; Adult; Aged; Child; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Risk Factors; Venous Thrombosis; Vitamin B 12; Vitamin B 6 | 2001 |
Human cobalamin deficiency: alterations in serum tumour necrosis factor-alpha and epidermal growth factor.
Topics: Adult; Aged; Aged, 80 and over; Anemia, Hypochromic; Anemia, Megaloblastic; Animals; Bone Marrow; Epidermal Growth Factor; Female; Folic Acid; Follow-Up Studies; Gastritis, Atrophic; Homocysteine; Humans; Iron; Iron Deficiencies; Male; Middle Aged; Peripheral Nervous System Diseases; Rats; Species Specificity; Tumor Necrosis Factor-alpha; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Plasma S-adenosylhomocysteine is a more sensitive indicator of cardiovascular disease than plasma homocysteine.
Topics: Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Sensitivity and Specificity; Vitamin B 12 | 2001 |
Cardiovascular disease risk factors and diet of Fulani pastoralists of northern Nigeria.
Topics: Adolescent; Adult; Aged; Body Composition; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Diet; Dietary Fats; Electric Impedance; Energy Intake; Exercise; Female; Folic Acid; Food Analysis; Homocysteine; Humans; Lipids; Male; Mental Recall; Middle Aged; Nigeria; Risk Factors; Surveys and Questionnaires; Vitamin B 12 | 2001 |
High prevalence of low serum vitamin B12 in a multi-ethnic Israeli population.
Topics: Adult; Arabs; Blood Donors; Case-Control Studies; Chi-Square Distribution; Female; Gaucher Disease; Homocysteine; Humans; Iraq; Israel; Jews; Male; Methylmalonic Acid; Morocco; Prevalence; Tunisia; Vitamin B 12; Vitamin B 12 Deficiency; Yemen | 2001 |
Total homocysteine is making its way into pediatric laboratory diagnostics.
Topics: Adult; Avitaminosis; Child; Diagnosis, Differential; Female; Folic Acid; Folic Acid Deficiency; HIV Infections; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Male; Methylmalonic Acid; Pediatrics; Pregnancy; Vitamin B 12 | 2001 |
Hyperhomocysteinaemia and folate deficiency in human immunodeficiency virus-infected children.
Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Female; Folic Acid Deficiency; HIV Infections; HIV-1; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Male; Methionine; Statistics as Topic; Vitamin B 12 | 2001 |
Methylenetetrahydrofolate reductase gene polymorphism, hyperhomocysteinemia, and cardiovascular diseases in chronic hemodialysis patients.
Topics: Adult; Aged; Cardiovascular Diseases; Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidoreductases Acting on CH-NH Group Donors; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Renal Dialysis; Risk Factors; Statistics as Topic; Vitamin B 12 | 2002 |
Nutrition. B vitamins.
Topics: Age Factors; Alzheimer Disease; Diet; Homocysteine; Humans; Myocardial Infarction; Vitamin B 12; Vitamin B 6 | 2001 |
Metabolism of amino acids in cats with severe cobalamin deficiency.
Topics: Amino Acids; Animals; Cat Diseases; Cats; Cystathionine; Cysteine; Female; Gastrointestinal Diseases; Homocysteine; Immunoassay; Male; Methionine; Methylmalonic Acid; Statistics, Nonparametric; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Assessment of prothrombotic risk in patients with Behçet's disease should include homocysteine plasma levels.
Topics: Behcet Syndrome; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Risk Factors; Thromboembolism; Vitamin B 12; Vitamin B 6 | 2001 |
Plasma total homocysteine and subarachnoid haemorrhage in a co-factor replete population.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Incidence; Male; Middle Aged; Prospective Studies; Subarachnoid Hemorrhage; Vitamin B 12 | 2001 |
Vitamin B12 metabolism after urinary diversion with a Kock ileal reservoir.
Topics: Adult; Aged; Female; Follow-Up Studies; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Schilling Test; Urinary Diversion; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Plasma folate but not vitamin B(12) or homocysteine concentrations are reduced after short-term vitamin B(6) supplementation.
Topics: Adult; Area Under Curve; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Pyridoxal Phosphate; Pyridoxine; Vitamin B 12; Vitamin B 6 | 2001 |
MTRR and MTHFR polymorphism: link to Down syndrome?
Topics: Alleles; Case-Control Studies; Child; Down Syndrome; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Vitamin B 12 | 2002 |
Homocysteine levels in elderly Spanish people: influence of pyridoxine, vitamin B12 and folic acid intakes.
Topics: Aged; Aged, 80 and over; Aging; Chromatography, High Pressure Liquid; Diet Records; Female; Folic Acid; Geriatric Assessment; Homocysteine; Humans; Male; Prospective Studies; Pyridoxine; Spain; Vitamin B 12 | 2002 |
Plasma homocysteine levels in Taiwanese vegetarians are higher than those of omnivores.
Topics: Adult; Amino Acids; Cardiovascular Diseases; Diet, Vegetarian; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Nutritional Status; Regression Analysis; Risk Factors; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2002 |
The Chilean flour folic acid fortification program reduces serum homocysteine levels and masks vitamin B-12 deficiency in elderly people.
Topics: Aged; Cardiovascular Diseases; Chile; Cholesterol, HDL; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nutritional Status; Prevalence; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Fortification of food with vitamin B12 in addition to folic acid might reduce cardiovascular disease risk.
Topics: Cardiovascular Diseases; Folic Acid; Food, Fortified; Homocysteine; Humans; Ireland; United Kingdom; Vitamin B 12 | 2002 |
Total homocysteine and cognitive deterioration in people with type 2 diabetes.
Topics: Aged; Albuminuria; Cholesterol; Cognition; Cognition Disorders; Diabetes Mellitus, Type 2; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Lipoproteins; Male; Middle Aged; Triglycerides; Vitamin B 12 | 2002 |
[Relationship between folate, vitamin B12, total plasma homocysteine and mutation of reductase].
Topics: Adult; Female; Folic Acid; Genotype; Homocysteine; Homozygote; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Vitamin B 12 | 2000 |
[Effects of homocysteine on cardiovascular development in early chicken embryo].
Topics: Animals; Cardiovascular System; Chick Embryo; Folic Acid; Heart Defects, Congenital; Homocysteine; Vitamin B 12 | 1999 |
Relation of homocysteine, vitamin B(12), and folate to coronary in-stent restenosis.
Topics: Aged; Angioplasty, Balloon, Coronary; Coronary Angiography; Coronary Disease; Coronary Restenosis; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Risk Factors; Stents; Vitamin B 12 | 2002 |
Abnormal cobalamin-dependent transmethylation in AIDS-associated myelopathy.
Topics: Adult; Female; Glutathione; HIV Infections; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged; S-Adenosylmethionine; Spinal Cord Diseases; Vitamin B 12 | 2002 |
Plasma homocysteine is not a major risk factor for vascular disease in growth hormone deficient adults.
Topics: Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Creatinine; Female; Folic Acid; Growth Hormone; Homocysteine; Humans; Lipids; Male; Middle Aged; Risk Factors; Statistics, Nonparametric; Vitamin B 12 | 2001 |
Correlates of plasma homocysteine, cysteine and cysteinyl-glycine in respondents in the British National Diet and Nutrition Survey of young people aged 4-18 years, and a comparison with the survey of people aged 65 years and over.
Topics: Adolescent; Aged; Aging; Biomarkers; Child; Child, Preschool; Cysteine; Diet Surveys; Dipeptides; Female; Folic Acid; Homocysteine; Humans; Male; Reference Values; Seasons; Sex Factors; Smoking; United Kingdom; Vitamin B 12; Vitamin B 6 | 2002 |
Maternal and fetal plasma homocysteine concentrations at birth: the influence of folate, vitamin B12, and the 5,10-methylenetetrahydrofolate reductase 677C-->T variant.
Topics: Female; Fetal Blood; Folic Acid; Genetic Variation; Genotype; Homocysteine; Humans; Labor, Obstetric; Methylenetetrahydrofolate Reductase (NADPH2); Osmolar Concentration; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Vitamin B 12 | 2002 |
Usefulness of plasma vitamin B(6), B(12), folate, homocysteine, and creatinine in predicting outcomes in heart transplant recipients.
Topics: Adult; Biomarkers; Creatinine; Female; Folic Acid; Heart Transplantation; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Risk Assessment; Risk Factors; Survival Analysis; Thrombosis; Vitamin B 12; Vitamin B 6 | 2002 |
Plasma total homocysteine and cysteine levels as cardiovascular risk factors in coronary heart disease.
Topics: Aged; Case-Control Studies; Coronary Disease; Cysteine; Dipeptides; Female; Folic Acid; Homocysteine; Humans; Lipoproteins, VLDL; Male; Middle Aged; Risk Factors; Triglycerides; Vitamin B 12 | 2002 |
Homocysteine and atheromatous renal artery stenosis.
Topics: Aged; Alleles; Arteriosclerosis; Case-Control Studies; Cystathionine beta-Synthase; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Renal Artery Obstruction; Risk Factors; Vitamin B 12 | 2001 |
Optimization of folic acid, vitamin B(12), and vitamin B(6) supplements in pediatric patients with sickle cell disease.
Topics: Adolescent; Anemia, Sickle Cell; Child; Dietary Supplements; Erythrocytes; Female; Folic Acid; Hemoglobin SC Disease; Homocysteine; Humans; Male; Nutrition Policy; Vitamin B 12; Vitamin B 6 | 2002 |
[Homocysteine, methylenetetrahydrofolate reductase/C677T genotype and risk for coronary heart disease. The AtheroGene study].
Topics: Case-Control Studies; Coronary Disease; Female; Folic Acid; Genotype; Germany; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prevalence; Risk Factors; Vitamin B 12 | 2002 |
Homocysteine, B vitamin status, and cognitive function in the elderly.
Topics: Aged; Aging; Cognition; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Intelligence; Male; Psychological Tests; Vitamin B 12 | 2002 |
Electrochemical and spectral studies of the reactions of aquocobalamin with nitric oxide and nitrite ion.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anions; Catalysis; Electrochemistry; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Homocysteine; Hydroxocobalamin; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methionine; Molecular Structure; Nitric Oxide; Nitrites; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Vitamin B 12 | 2002 |
Vitamin B(12) deficiency associated with histamine(2)-receptor antagonists and a proton-pump inhibitor.
Topics: Aged; Cimetidine; Creatinine; Enzyme Inhibitors; Female; Folic Acid; Gastroesophageal Reflux; Histamine H2 Antagonists; Homocysteine; Humans; Methylmalonic Acid; Omeprazole; Proton Pump Inhibitors; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Methylenetetrahydrofolate reductase genotype, vitamin B12, and folate influence plasma homocysteine in hemodialysis patients.
Topics: Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Renal Dialysis; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
5-methyltetrahydrofolate restores endothelial function in uraemic patients on convective haemodialysis.
Topics: Drug Therapy, Combination; Endothelium, Vascular; Female; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Injections, Intravenous; Injections, Subcutaneous; Male; Middle Aged; Renal Dialysis; Tetrahydrofolates; Ultrasonography; Uremia; Vasodilation; Vitamin B 12 | 2002 |
Hyperhomocyst(e)inemia and MTHFR C677T genotypes in patients with central retinal vein occlusion.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymerase Chain Reaction; Retinal Vein Occlusion; Retrospective Studies; Risk Factors; Vitamin B 12 | 2002 |
Relation of Helicobacter pylori infection to plasma vitamin B12, folic acid, and homocysteine levels in patients who underwent diagnostic coronary arteriography.
Topics: Aged; Coronary Angiography; Coronary Artery Disease; Female; Folic Acid; Gastritis, Atrophic; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Malabsorption Syndromes; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2002 |
Functional vitamin B(12) deficiency and Alzheimer disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alzheimer Disease; Brain; Homocysteine; Humans; Hyperhomocysteinemia; Oxidation-Reduction; Oxidative Stress; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Effect of vegetarian diet on homocysteine levels.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Luminescent Measurements; Male; Middle Aged; Prevalence; Vitamin B 12 | 2002 |
Prevalence of hyperhomocysteinemia in an elderly population.
Topics: Age Distribution; Aged; Aged, 80 and over; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Sex Distribution; Vitamin B 12 | 2002 |
The C677T thermolabile variant of methylene tetrahydrofolate reductase on homocysteine, folate and vitamin B12 in a hemodialysis center.
Topics: Adult; Chi-Square Distribution; Female; Folic Acid; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Renal Dialysis; Statistics, Nonparametric; Vitamin B 12 | 2002 |
Folic acid, Vitamin B(12), and homocysteine in smoking and non-smoking pregnant women.
Topics: Cross-Sectional Studies; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Nutritional Status; Pregnancy; Pregnancy Complications; Reference Values; Smoking; Vitamin B 12 | 2002 |
Hyperhomocyst(e)inemia, but not methylenetetrahydrofolate reductase C677T mutation, as a risk factor in branch retinal vein occlusion.
Topics: Adult; Aged; Aged, 80 and over; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2002 |
Erythrocyte mean cellular volume and its relation to serum homocysteine, vitamin B12 and folate.
Topics: Cerebrovascular Disorders; Erythrocyte Volume; Female; Folic Acid; Hemodynamics; Hemoglobins; Homocysteine; Humans; Male; Middle Aged; Vascular Diseases; Vitamin B 12 | 2002 |
Early-onset cobalamin C/D deficiency: epilepsy and electroencephalographic features.
Topics: Age of Onset; Brain; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Homocysteine; Homocystine; Homocystinuria; Humans; Infant; Infant, Newborn; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Sleep; Vitamin B 12; Vitamin B 12 Deficiency; Wakefulness | 2002 |
Vitamin B12 and folate after 5-12 years of continent ileal urostomy (Kock reservoir) in children and adolescents.
Topics: Adolescent; Child; Child Welfare; Colonic Pouches; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Glomerular Filtration Rate; Hemoglobins; Homocysteine; Humans; Ileum; Iron; Kidney; Male; Methylmalonic Acid; Postoperative Complications; Prospective Studies; Time Factors; Ureterostomy; Urinary Reservoirs, Continent; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Reduced plasma homocysteine in obese red wine consumers: a potential contributor to reduced cardiovascular risk status.
Topics: Adult; Alcohol Drinking; Alcoholic Beverages; Beer; Cardiovascular Diseases; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Obesity, Morbid; Risk; Vitamin B 12; Wine | 2002 |
[Keep serum cobalamin determination as a sift-test].
Topics: Biomarkers; Diagnosis, Differential; Homocysteine; Humans; Mass Screening; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Hyperhomocysteinemia, and low intakes of folic acid and vitamin B12 in urban North India.
Topics: Adult; Anthropometry; Blood Chemical Analysis; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Mental Recall; Obesity; Poverty Areas; Seroepidemiologic Studies; Urban Population; Vitamin B 12 | 2002 |
Methionine synthase polymorphism A2756G is associated with susceptibility for thromboembolic events and altered B vitamin/thiol metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Genetic Predisposition to Disease; Glutathione; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Prevalence; Sulfhydryl Compounds; Thromboembolism; Vitamin B 12 | 2002 |
Transcobalamin II 775G>C polymorphism and indices of vitamin B12 status in healthy older adults.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Homocysteine and C-reactive protein levels in haemodialysis patients.
Topics: Adult; C-Reactive Protein; Case-Control Studies; Coronary Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Vitamin B 12 | 2001 |
Vitamin B-12 status is inversely associated with plasma homocysteine in young women with C677T and/or A1298C methylenetetrahydrofolate reductase polymorphisms.
Topics: Adult; Dietary Supplements; Female; Folic Acid; Forecasting; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Osmolar Concentration; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Regression Analysis; Vitamin B 12 | 2002 |
Low vitamin B-12 intake and status are more prevalent in Hispanic older adults of Caribbean origin than in neighborhood-matched non-Hispanic whites.
Topics: Aged; Aged, 80 and over; Aging; Diet; Dominican Republic; Hispanic or Latino; Homocysteine; Humans; Middle Aged; Prevalence; Puerto Rico; Vitamin B 12; Vitamin B 12 Deficiency; White People | 2002 |
Homocysteine levels in patients with Raynaud's phenomenon.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Prospective Studies; Raynaud Disease; Reference Values; Vitamin B 12 | 2002 |
Antisense inhibition of methylenetetrahydrofolate reductase reduces survival of methionine-dependent tumour lines.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line; Colonic Neoplasms; Enzyme Inhibitors; Exons; Female; Fibroblasts; Genetic Therapy; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasm Proteins; Neuroblastoma; Oligodeoxyribonucleotides, Antisense; Oxidoreductases Acting on CH-NH Group Donors; RNA, Messenger; RNA, Neoplasm; Thionucleotides; Tumor Cells, Cultured; Vitamin B 12 | 2002 |
Endothelial function in healthy younger and older hyperhomocysteinemic subjects.
Topics: Adolescent; Adult; Age Factors; Aged; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Vasodilation; Vitamin B 12 | 2002 |
Hyperhomocysteinemia and cobalamin deficiency in young Asian Indians in the United States.
Topics: Adult; Diet, Vegetarian; Female; Folic Acid; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Hyperhomocysteinemia; India; Malabsorption Syndromes; Male; Sex Factors; United States; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
[Formulation of tablets decreasing plasma homocysteine levels].
Topics: Cellulose; Folic Acid; Homocysteine; Humans; Reproducibility of Results; Tablets; Vitamin B 12; Vitamin B 6 | 2001 |
Effect of supplementation with folic-acid on relation between plasma homocysteine, folate, and vitamin B12.
Topics: Aged; Case-Control Studies; Dementia; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Transcobalamins; Vitamin B 12 | 2002 |
[Investigation of relationship between pregnancy induced hypertension syndrome and homocysteine, folic acid and vitamin B(12)].
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Vitamin B 12 | 2002 |
Relationship between total homocysteine and folate levels in pregnant women and their newborn babies according to maternal serum levels of vitamin B12.
Topics: Adolescent; Adult; Biomarkers; Cross-Sectional Studies; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Nutritional Status; Pregnancy; Regression Analysis; Vitamin B 12 | 2002 |
Evidence of poor vitamin status in coeliac patients on a gluten-free diet for 10 years.
Topics: Celiac Disease; Cohort Studies; Energy Intake; Female; Folic Acid; Glutens; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Remission Induction; Vitamin B 12; Vitamins | 2002 |
Is low-dose oral cobalamin enough to normalize cobalamin function in older people?
Topics: Administration, Oral; Aged; Aged, 80 and over; Cross-Sectional Studies; Dietary Supplements; Female; Homocysteine; Humans; Male; Methylglycosides; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Plasma homocysteine concentration changes after renal transplantation in children.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Male; Serum Albumin; Vitamin B 12 | 2002 |
[Frequency of hyperhomocysteinemia in hemodialysis patients with folic acid supplementation].
Topics: Adult; Age Factors; Aged; Female; Folic Acid; Hemodiafiltration; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Renal Dialysis; Time Factors; Vitamin B 12 | 2002 |
Low plasma antioxidants and normal plasma B vitamins and homocysteine in patients with severe obesity.
Topics: Adult; Body Mass Index; Carotenoids; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Obesity; Vitamin B 12; Vitamin E; Vitamins | 2002 |
Methylenetetrahydrofolate reductase gene mutation and hyperhomocysteinemia as a risk factor for coronary heart disease in the Indian population.
Topics: Adult; Coronary Disease; Cystathionine beta-Synthase; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Risk Factors; Vitamin B 12 | 2002 |
Serum lipid profiles and risk of cardiovascular disease in three different male populations in northern Nigeria.
Topics: Adult; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Male; Nigeria; Risk Factors; Triglycerides; Vitamin B 12 | 2002 |
Major gene evidence after MTHFR-segregation analysis of serum homocysteine in families of patients undergoing coronary arteriography.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Chromosome Segregation; Coronary Angiography; Coronary Artery Disease; Family; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pedigree; Vitamin B 12 | 2002 |
Polymorphisms in the transcobalamin gene: association with plasma homocysteine in healthy individuals and vascular disease patients.
Topics: Female; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Genetic; Risk Factors; Transcobalamins; Vascular Diseases; Vitamin B 12 | 2002 |
Homocysteine, nutritional status and insulin in renal transplant recipients.
Topics: Blood Glucose; C-Peptide; Creatinine; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Immunosuppressive Agents; Insulin; Kidney Transplantation; Lipids; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Vitamin B 12 | 2002 |
Influence of a glutamate carboxypeptidase II (GCPII) polymorphism (1561C-->T) on plasma homocysteine, folate and vitamin B(12) levels and its relationship to cardiovascular disease risk.
Topics: Adult; Analysis of Variance; Antigens, Surface; Carboxypeptidases; Cardiovascular Diseases; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Glutamate Carboxypeptidase II; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Probability; Reference Values; Risk Assessment; Sensitivity and Specificity; Vitamin B 12 | 2002 |
Effects of serum B vitamins on elevated plasma homocysteine levels associated with the mutation of methylenetetrahydrofolate reductase gene in Japanese.
Topics: Adult; Age Distribution; Aged; Arteriosclerosis; Cross-Sectional Studies; Data Collection; Female; Folic Acid; Genotype; Homocysteine; Humans; Incidence; Japan; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Probability; Reference Values; Risk Assessment; Sampling Studies; Sensitivity and Specificity; Sex Distribution; Vitamin B 12; Vitamin B 6 | 2002 |
Low Vitamin B(12) level as a risk factor for very early recurrent abortion.
Topics: Abortion, Habitual; Adult; Dietary Supplements; Female; Gestational Age; Homocysteine; Humans; Pregnancy; Pregnancy Outcome; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Hyperhomocysteinemia in children with renal transplants.
Topics: Adolescent; Blood Glucose; Child; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Lipids; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Regression Analysis; Vitamin B 12 | 2002 |
Elevated serum methylmalonic acid concentrations are common among elderly Americans.
Topics: Adult; Aged; Aging; Black or African American; Creatinine; Female; Folic Acid; Hispanic or Latino; Homocysteine; Humans; Male; Methylmalonic Acid; Nutrition Surveys; Vitamin B 12; Vitamin B 12 Deficiency; White People | 2002 |
Homocysteine and other vascular risk factors in patients with phenylketonuria on a diet.
Topics: Child; Child, Preschool; Coronary Artery Disease; Diet, Protein-Restricted; Endothelin-1; Folic Acid; Homocysteine; Humans; Lipids; Nutrition Assessment; Phenylalanine; Phenylketonurias; Risk Factors; Vitamin B 12; Vitamin B 6 | 2002 |
Influence of age, sex, folate and vitamin B12 status on plasma homocysteine in Saudis.
Topics: Adult; Aged; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Saudi Arabia; Sex Characteristics; Vitamin B 12 | 2002 |
Folate levels in pregnant women who smoke: an important gene/environment interaction.
Topics: Adult; Cotinine; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Smoking; Vitamin B 12 | 2002 |
Efficacy of a complex multivitamin supplement.
Topics: Adult; Aged; Antioxidants; Ascorbic Acid; beta Carotene; Cohort Studies; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Lipid Peroxidation; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Pilot Projects; Pyridoxal Phosphate; Pyridoxine; Vitamin B 12; Vitamin E; Vitamins | 2002 |
Smoking and plasma homocysteine.
Topics: Adult; Cardiovascular Diseases; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Smoking; Vitamin B 12; Vitamin B 6 | 2002 |
Relation of blood homocysteine and its nutritional determinants to age-related maculopathy in the third National Health and Nutrition Examination Survey.
Topics: Adult; Black People; Erythrocytes; Fluorescein Angiography; Folic Acid; Homocysteine; Humans; Macular Degeneration; Nutrition Surveys; Nutritional Status; Odds Ratio; Risk Factors; Vitamin B 12; White People | 2002 |
Optimal use of markers for cobalamin and folate status in a psychogeriatric population.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Vitamin B 12 | 2002 |
Essential hypertension in adolescents: association with insulin resistance and with metabolism of homocysteine and vitamins.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Cystathionine beta-Synthase; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hypertension; Insulin Resistance; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prevalence; Risk Factors; Vitamin B 12; Vitamin B 6 | 2002 |
Role of impaired renal function as a cause of elevated plasma homocysteine concentration in psychogeriatric patients.
Topics: Age Factors; Aged; Creatinine; Cystatin C; Cystatins; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Male; Mental Disorders; Predictive Value of Tests; Vitamin B 12 | 2002 |
Homocysteine, folate and vitamin B12 as risk factors for acute myocardial infarction in a Southeast Asian population.
Topics: Adult; Aged; Asian People; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Logistic Models; Male; Middle Aged; Myocardial Infarction; Risk Factors; Seroepidemiologic Studies; Singapore; Vitamin B 12 | 2002 |
Cobalamin status (holo-transcobalamin, methylmalonic acid) and folate as determinants of homocysteine concentration.
Topics: Adult; Aged; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12 | 2002 |
Plasma homocyst(e)ine, folate and vitamin B(12) levels among school children in Taiwan: The Taipei Children Heart Study.
Topics: Adolescent; Analysis of Variance; Anthropometry; Blood Pressure; Cardiovascular Diseases; Child; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Risk Factors; Sex Characteristics; Statistics, Nonparametric; Surveys and Questionnaires; Taiwan; Vitamin B 12 | 2002 |
Lack of association between plasma homocysteine and angiographic coronary artery disease in the era of fortification of cereal grain flour with folic acid.
Topics: Adult; Aged; Coronary Angiography; Coronary Disease; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Severity of Illness Index; Vitamin B 12 | 2002 |
Sustained increases of plasma homocysteine, copper, and serum ceruloplasmin after coronary artery bypass grafting.
Topics: Aged; Cardiopulmonary Bypass; Ceruloplasmin; Copper; Coronary Artery Bypass; Coronary Disease; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Minimally Invasive Surgical Procedures; Postoperative Complications; Risk Factors; Vitamin B 12 | 2002 |
Homocysteine, cardiovascular disease risk factors, and habitual diet in the French Supplementation with Antioxidant Vitamins and Minerals Study.
Topics: Adult; Aging; Alcohol Drinking; Antioxidants; Apolipoproteins B; Blood Glucose; Body Constitution; Body Mass Index; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Coffee; Dietary Fiber; Dietary Supplements; Energy Intake; Erythrocytes; Exercise; Fasting; Female; Folic Acid; France; Homocysteine; Humans; Male; Middle Aged; Minerals; Risk Factors; Sex Characteristics; Triglycerides; Vitamin B 12; Vitamin B 6; Vitamins | 2002 |
Preconception homocysteine and B vitamin status and birth outcomes in Chinese women.
Topics: Adult; Body Mass Index; Body Weight; Case-Control Studies; China; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Small for Gestational Age; Nutritional Status; Obstetric Labor, Premature; Preconception Care; Pregnancy; Pregnancy Outcome; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2002 |
Molecular characterization of a cystathionine beta-synthase gene, CBS1, in Magnaporthe grisea.
Topics: Amino Acid Sequence; Cystathionine; Cystathionine beta-Synthase; Genes, Fungal; Homocysteine; Magnaporthe; Mitochondrial Proteins; Molecular Sequence Data; Plant Diseases; Saccharomyces cerevisiae Proteins; Sequence Alignment; Sequence Analysis, Protein; Trans-Activators; Vitamin B 12 | 2002 |
Can homocysteine be related to physical functioning?
Topics: Aged; Aging; Folic Acid; Homocysteine; Humans; Psychomotor Performance; Vitamin B 12; Vitamin B 6 | 2002 |
Homocysteine and methylmalonic acid: markers to predict and avoid toxicity from pemetrexed therapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Folic Acid; Glutamates; Guanine; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Models, Biological; Multivariate Analysis; Odds Ratio; Pemetrexed; Time Factors; Vitamin B 12 | 2002 |
Fruit and vegetable intake and chronic disease risk in Portugal.
Topics: Antioxidants; Biomarkers; Cardiovascular Diseases; Carotenoids; Female; Folic Acid; Fruit; Homocysteine; Humans; Male; Middle Aged; Morbidity; Neoplasms; Portugal; Risk Factors; Surveys and Questionnaires; Vegetables; Vitamin B 12; Vitamin B 6; Vitamin E | 2002 |
Moderate hyperhomocysteinaemia and immune activation in Parkinson's disease.
Topics: Aged; Aged, 80 and over; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neopterin; Parkinson Disease; Vitamin B 12 | 2002 |
Plasma total homocysteine, folate, and vitamin B12 status in Korean adults.
Topics: Adult; Age Factors; Aged; Area Under Curve; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Korea; Male; Middle Aged; Nutritional Status; Prevalence; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Predictors of cobalamin deficiency in Guatemalan school children: diet, Helicobacter pylori, or bacterial overgrowth?
Topics: Analysis of Variance; Breath Tests; Child; Diet; Female; Gastrins; Guatemala; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Male; Methylmalonic Acid; Pepsinogen A; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
[Therapy of hyperhomocysteinemia with vitamin B12].
Topics: Adult; Diet, Vegetarian; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
The effect of folic acid, vitamin B6 and vitamin B12 on the homocysteine levels in rabbits fed by methionine-enriched diets.
Topics: Animals; Diet; Dose-Response Relationship, Drug; Drug Combinations; Female; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rabbits; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2002 |
Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism.
Topics: Anemia; Anemia, Pernicious; Cysteine; Dipeptides; Folic Acid; Glutathione; Homocysteine; Humans; Memory Disorders; Methionine; Movement Disorders; Nervous System Diseases; Retrospective Studies; S-Adenosylmethionine; Sensation Disorders; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Hyperhomocysteinemia is related to a decreased blood level of vitamin B12 in the second and third trimester of normal pregnancy.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intrinsic Factor; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Receptors, Peptide; Statistics as Topic; Vitamin B 12 | 2002 |
Methylenetetrahydrofolate reductase gene C677T polymorphism, homocysteine, vitamin B12, and DNA damage in coronary artery disease.
Topics: Aged; Alleles; Carotid Artery Diseases; Coronary Angiography; Cytosine; DNA; DNA Damage; DNA Mutational Analysis; DNA Primers; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Micronucleus Tests; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Factors; Thymidine; Vitamin B 12 | 2003 |
Elevated plasma homocysteine levels in patients treated with levodopa: association with vascular disease.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Parkinson Disease; Risk Factors; Vitamin B 12 | 2003 |
Vitamin B-12 metabolism in HIV-infected patients in the age of highly active antiretroviral therapy: role of homocysteine in assessing vitamin B-12 status.
Topics: Adult; Antiretroviral Therapy, Highly Active; Diagnosis, Differential; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; HIV Infections; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nutrition Assessment; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
High prevalence of cobalamin deficiency in Guatemalan schoolchildren: associations with low plasma holotranscobalamin II and elevated serum methylmalonic acid and plasma homocysteine concentrations.
Topics: Analysis of Variance; Anemia; Biomarkers; Child; Creatinine; Female; Folic Acid; Guatemala; Hematocrit; Hemoglobins; Homocysteine; Humans; Male; Mass Screening; Methylmalonic Acid; Prevalence; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Folate intake, plasma folate and homocysteine status in a random Finnish population.
Topics: Adult; Aged; Biomarkers; Diet; Dietary Supplements; Female; Finland; Folic Acid; Genotype; Homocysteine; Homozygote; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutritional Status; Oxidoreductases Acting on CH-NH Group Donors; Vitamin B 12 | 2003 |
CblE type of homocystinuria due to methionine synthase reductase deficiency: clinical and molecular studies and prenatal diagnosis in two families.
Topics: Adult; Anemia, Megaloblastic; Base Sequence; Cells, Cultured; Child; Chromatography, Ion Exchange; DNA; Female; Ferredoxin-NADP Reductase; Fibroblasts; Folic Acid; Homocysteine; Homocystinuria; Humans; Methionine; Molecular Sequence Data; Mutation; Prenatal Diagnosis; Reverse Transcriptase Polymerase Chain Reaction; Serine; Vitamin B 12 | 2002 |
Alzheimer's disease and total plasma aminothiols.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chromatography, High Pressure Liquid; Cysteine; Folic Acid; Glutathione; Homocysteine; Humans; Mental Status Schedule; Neuropsychological Tests; Prognosis; Reference Values; Vitamin B 12 | 2003 |
Relationship between methylmalonic acid, homocysteine, vitamin B12 intake and status and socio-economic indices, in a subset of participants in the British National Diet and Nutrition Survey of people aged 65 y and over.
Topics: Aged; Analysis of Variance; Cross-Sectional Studies; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Nutrition Surveys; Nutritional Status; Socioeconomic Factors; United Kingdom; Vitamin B 12 | 2003 |
Effects of valproate and carbamazepine on serum levels of homocysteine, vitamin B12, and folic acid.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Reference Values; Valproic Acid; Vitamin B 12 | 2003 |
Serum homocysteine level in Behçet's disease.
Topics: Adult; Behcet Syndrome; Case-Control Studies; Female; Fluorescence Polarization Immunoassay; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Vitamin B 12 | 2002 |
Soy product intake is inversely associated with serum homocysteine level in premenopausal Japanese women.
Topics: Adult; Diet; Female; Folic Acid; Glycine max; Homocysteine; Humans; Isoflavones; Methionine; Middle Aged; Nutritional Status; Premenopause; Soybean Proteins; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6 | 2003 |
Vitamin B-12 status is associated with bone mineral content and bone mineral density in frail elderly women but not in men.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Body Composition; Body Height; Body Weight; Bone Density; Calcium, Dietary; Female; Frail Elderly; Homocysteine; Humans; Male; Methylmalonic Acid; Netherlands; Nutritional Status; Odds Ratio; Osteoporosis; Parathyroid Hormone; Regression Analysis; Sex Characteristics; Smoking; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D | 2003 |
Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of breast cancer.
Topics: Adult; Aged; Alcohol Drinking; Breast Neoplasms; Case-Control Studies; Confidence Intervals; Female; Folic Acid; Homocysteine; Humans; Life Style; Medical History Taking; Middle Aged; Multivariate Analysis; Nurses; Risk Assessment; Risk Factors; Surveys and Questionnaires; United States; Vitamin B 12; Vitamin B 6 | 2003 |
Hyperhomocysteinemia in Asian Indians living in the United States.
Topics: Adult; Area Under Curve; Blood Glucose; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Insulin; Male; Middle Aged; United States; Vitamin B 12; White People | 2003 |
Familial hyperhomocysteinemia: multiple venous thrombosis in four generations of a family.
Topics: Adult; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nitroprusside; Pedigree; Venous Thrombosis; Vitamin B 12; Warfarin | 2003 |
The status of plasma homocysteine and related B-vitamins in healthy young vegetarians and nonvegetarians.
Topics: Adult; Diet, Vegetarian; Dietary Proteins; Female; Folic Acid; Homocysteine; Humans; Male; Nutritional Status; Reference Values; Regression Analysis; Vitamin B 12; Vitamin B 6 | 2003 |
Is there any relationship between lipids and vitamin B levels in persons with elevated risk of atherosclerosis?
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Cardiac Surgical Procedures; Case-Control Studies; Cholesterol; Female; Folic Acid; Homocysteine; Humans; Hyperlipidemias; Lipids; Male; Middle Aged; Risk Factors; Triglycerides; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2003 |
Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Cystathionine beta-Synthase; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Nutritional Status; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Vitamin B 12 | 2003 |
Homocysteine, folate, vitamin B12 levels, and C677T MTHFR mutation in children with renal failure.
Topics: Adolescent; Child; Child, Preschool; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Point Mutation; Predictive Value of Tests; Prevalence; Regression Analysis; Vitamin B 12 | 2003 |
Demographic, health, lifestyle, and blood vitamin determinants of serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey, 1988-1994.
Topics: Adult; Aged; Aging; Alcohol Drinking; Alcoholic Beverages; Beer; Black People; Body Mass Index; Cotinine; Dietary Supplements; Erythrocytes; Female; Folic Acid; Health Status; Hispanic or Latino; Homocysteine; Humans; Life Style; Linear Models; Male; Middle Aged; Nutrition Surveys; Sex Characteristics; Vitamin B 12; Vitamins; White People; Wine | 2003 |
Nutritional modulation of gene expression and homocysteine utilization by vitamin B12.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5' Untranslated Regions; Animals; Carcinoma, Hepatocellular; COS Cells; Gene Expression; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Kidney; Liver Neoplasms; Methylation; Nucleic Acid Conformation; Nutritional Physiological Phenomena; Polyribosomes; Protein Biosynthesis; RNA, Messenger; Tumor Cells, Cultured; Vitamin B 12 | 2003 |
Folate deficiency is a common finding in psychogeriatric patients.
Topics: Aged; Aged, 80 and over; Aging; Cognition Disorders; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Regression Analysis; Vitamin B 12 | 2002 |
Prevalence and mechanisms of hyperhomocysteinemia in elderly hospitalized patients.
Topics: Aged; Aged, 80 and over; Aging; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nutritional Status; Prevalence; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
[Hyperhomocysteinemia hastens myocardial infarct and stroke. Prevention.with leaf salads and vitamins].
Topics: Adult; Age Factors; Aged; Arteriosclerosis; Clinical Trials as Topic; Dementia; Diet; Drug Therapy, Combination; Female; Folic Acid; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Male; Myocardial Infarction; Prospective Studies; Risk Factors; Sex Factors; Stroke; Vegetables; Vitamin B 12; Vitamin B 6 | 2003 |
Genetic evidence that nitric oxide modulates homocysteine: the NOS3 894TT genotype is a risk factor for hyperhomocystenemia.
Topics: Adult; Amino Acid Substitution; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Northern Ireland; Point Mutation; Prospective Studies; Risk Factors; Vitamin B 12 | 2003 |
Serum homocysteine, B12 and folic acid concentration in Thai overweight and obese subjects.
Topics: Adolescent; Adult; Antioxidants; Ascorbic Acid; Body Constitution; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Obesity; Thailand; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2003 |
Plasma total homocysteine in uncomplicated pregnancy and in preeclampsia.
Topics: Case-Control Studies; Chromatography, High Pressure Liquid; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Vitamin B 12 | 2003 |
Determinants and distributions of plasma total homocysteine concentrations among school children in Taiwan.
Topics: Adolescent; Age Factors; Anthropometry; Cardiovascular Diseases; Child; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Schools; Sex Factors; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Hyperhomocysteinemia and vitamin score: correlations with silent brain ischemic lesions and brain atrophy.
Topics: Aged; Aged, 80 and over; Atrophy; Brain; Brain Ischemia; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12; Vitamin B 6; Vitamins | 2003 |
Screening for vitamin B-12 and folate deficiency in older persons.
Topics: Age Factors; Aged; Aged, 80 and over; Creatinine; Female; Folic Acid; Folic Acid Deficiency; Hemoglobins; Homocysteine; Humans; Male; Mass Screening; Methylmalonic Acid; Prevalence; Reference Values; Risk Factors; Sex Factors; United Kingdom; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Determinants of hyperhomocysteinemia in patients with chronic liver disease and after orthotopic liver transplantation.
Topics: Adult; Area Under Curve; Case-Control Studies; Chronic Disease; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver Diseases; Liver Transplantation; Male; Metabolic Clearance Rate; Methionine; Middle Aged; Vitamin B 12; Vitamin B 6 | 2003 |
Anemia, serum vitamin B12, and folic acid in patients with rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Arthritis, Psoriatic; Arthritis, Rheumatoid; Cohort Studies; Female; Folic Acid Deficiency; Homocysteine; Humans; Incidence; Israel; Lupus Erythematosus, Systemic; Male; Methylmalonic Acid; Middle Aged; Retrospective Studies; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
Homocysteine and other plasma amino acids in preeclampsia and in pregnancies without complications.
Topics: Adult; Amino Acids; Case-Control Studies; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Data Interpretation, Statistical; Female; Folic Acid; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Vitamin B 12 | 2003 |
Vitamin B12 and folate status of older New Zealand women.
Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; New Zealand; Nutritional Status; Prevalence; Vitamin B 12 | 2003 |
Low vitamin B6 but not homocyst(e)ine is associated with increased risk of stroke and transient ischemic attack in the era of folic acid grain fortification.
Topics: Case-Control Studies; Comorbidity; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Homocystine; Humans; Ischemic Attack, Transient; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxal Phosphate; Risk Assessment; Risk Factors; Serum Albumin; Stroke; United States; Vitamin B 12; Vitamin B 6 | 2003 |
Influence of training volume and acute physical exercise on the homocysteine levels in endurance-trained men: interactions with plasma folate and vitamin B12.
Topics: Adult; Exercise; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Physical Endurance; Reference Values; Time Factors; Vitamin B 12 | 2003 |
Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism and the B-vitamins: a facet of nature-nurture interplay.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6 | 2003 |
Plasma homocysteine and its relationships with atherothrombotic markers in psoriatic patients.
Topics: Acute-Phase Proteins; Adult; Arteriosclerosis; Autoantibodies; Biomarkers; Female; Fibrinogen; Fibronectins; Folic Acid; Homocysteine; Humans; Lipoproteins, LDL; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Psoriasis; Thrombosis; Tissue Plasminogen Activator; Vitamin B 12 | 2003 |
Homocysteine: a marker for cognitive performance? A longitudinal follow-up study.
Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Cognition; Cognition Disorders; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; Prospective Studies; Psychomotor Performance; Risk Factors; Vitamin B 12 | 2003 |
Homocysteine as a risk factor for nephropathy and retinopathy in Type 2 diabetes.
Topics: Age Factors; Analysis of Variance; Arizona; Biomarkers; Blood Glucose; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Folic Acid; Homocysteine; Humans; Incidence; Indians, North American; Longitudinal Studies; Male; Middle Aged; Vitamin B 12 | 2003 |
Folate, vitamin B12, and homocysteine status. findings of no relation between human papillomavirus persistence and cervical dysplasia.
Topics: Adolescent; Adult; Cervix Uteri; DNA, Viral; Female; Folic Acid; Homocysteine; Humans; Nutritional Status; Papillomaviridae; Papillomavirus Infections; Tumor Virus Infections; Uterine Cervical Dysplasia; Vitamin B 12 | 2003 |
Homocysteine, apolipoproteine E and methylenetetrahydrofolate reductase in Alzheimer's disease and mild cognitive impairment.
Topics: Aged; Alzheimer Disease; Apolipoproteins E; Cognition Disorders; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Vitamin B 12 | 2003 |
Serum homocysteine concentrations and their relation to serum folate and vitamin B12 concentrations and coronary artery disease prevalence in an urban, bi-ethnic community.
Topics: Aged; Coronary Artery Disease; Female; Folic Acid; Hispanic or Latino; Homocysteine; Humans; Male; New Mexico; Prospective Studies; Risk Factors; Urban Health; Vitamin B 12; White People | 2003 |
Lipoprotein oxidation, plasma total antioxidant capacity and homocysteine level in patients with multiple sclerosis.
Topics: Adult; Antioxidants; Autoantibodies; Chromans; Female; Folic Acid; Homocysteine; Humans; Lipid Peroxidation; Lipoproteins; Lipoproteins, LDL; Male; Multiple Sclerosis; Oxidation-Reduction; Oxidative Stress; Vitamin B 12; Vitamin E | 2003 |
Folate, vitamin B12, homocysteine, and the MTHFR 677C->T polymorphism in anxiety and depression: the Hordaland Homocysteine Study.
Topics: Aged; Anxiety Disorders; Cohort Studies; Cross-Sectional Studies; Depressive Disorder; Folic Acid; Genotype; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Norway; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Personality Inventory; Polymorphism, Genetic; Risk Factors; Vitamin B 12 | 2003 |
Serum homocysteine levels are increased in women with gestational diabetes mellitus.
Topics: Adult; Blood Glucose; Blood Pressure; Case-Control Studies; Diabetes, Gestational; Female; Folic Acid; Glucose Tolerance Test; Homocysteine; Humans; Male; Pregnancy; Serum Albumin; Uric Acid; Vitamin B 12 | 2003 |
B vitamins and plasma homocysteine concentrations in an urban and rural area of Costa Rica.
Topics: Adult; Aged; Alcohol Drinking; Blood Pressure; Body Constitution; Body Mass Index; Cardiovascular Diseases; Costa Rica; Diet; Educational Status; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Physical Fitness; Risk Factors; Rural Population; Sex Characteristics; Smoking; Urban Population; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2003 |
Urine methylmalonic acid measurements for the assessment of cobalamin deficiency related to neuropsychiatric disorders.
Topics: Adult; Aged; Folic Acid; Homocysteine; Humans; Mental Disorders; Methylmalonic Acid; Middle Aged; Photometry; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Increased plasma homocysteine levels without signs of vitamin B12 deficiency in patients with multiple sclerosis assessed by blood and cerebrospinal fluid homocysteine and methylmalonic acid.
Topics: Adult; Aged; Aged, 80 and over; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Multiple Sclerosis; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Vitamin B-12 status, particularly holotranscobalamin II and methylmalonic acid concentrations, and hyperhomocysteinemia in vegetarians.
Topics: Adult; Aged; Biomarkers; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Middle Aged; Osmolar Concentration; Transcobalamins; Vitamin B 12 | 2003 |
Factors modulating conformational equilibria in large modular proteins: a case study with cobalamin-dependent methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Substitution; Catalysis; Escherichia coli; Escherichia coli Proteins; Homocysteine; Methionine; Methylation; Mutation, Missense; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity; Temperature; Tetrahydrofolates; Vitamin B 12 | 2003 |
Study on the relationship between plasma homocysteine and acute cerebral vascular disease.
Topics: Cerebral Hemorrhage; Cerebral Infarction; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2000 |
Interaction between common folate polymorphisms and B-vitamin nutritional status modulates homocysteine and risk for a thrombotic event.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Alleles; Data Interpretation, Statistical; Ferredoxin-NADP Reductase; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Nutritional Status; Point Mutation; Polymorphism, Single Nucleotide; Prevalence; Reverse Transcriptase Polymerase Chain Reaction; Thromboembolism; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Re: Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of breast cancer.
Topics: Anticarcinogenic Agents; Austria; Biomarkers, Tumor; Breast Neoplasms; Female; Folic Acid; Homocysteine; Humans; Risk Assessment; Vitamin B 12; Vitamin B 6 | 2003 |
Homocysteine plasma levels after suspension of vitamin treatment.
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Clinical Protocols; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Vitamin B 12 | 2003 |
Treatment of hyperhomocysteinemia in pediatric heart transplant recipients.
Topics: Adolescent; Antioxidants; Biomarkers; Child; Child Welfare; Child, Preschool; Combined Modality Therapy; Creatinine; Female; Folic Acid; Follow-Up Studies; Heart Transplantation; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant Welfare; Male; Statistics as Topic; Treatment Outcome; Vitamin A; Vitamin B 12; Vitamin E | 2003 |
Plasma thiols and their determinants in phenylketonuria.
Topics: Adolescent; Cross-Sectional Studies; Cysteine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Male; Methionine; Phenylalanine; Phenylketonurias; Sulfhydryl Compounds; Vitamin B 12 | 2003 |
The 2756A>G variant in the gene encoding methionine synthase: its relation with plasma homocysteine levels and risk of coronary heart disease in a Dutch case-control study.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenine; Case-Control Studies; Coronary Disease; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Guanine; Homocysteine; Humans; Middle Aged; Osmolar Concentration; Risk Factors; Vitamin B 12 | 2003 |
Effect of TCN2 776C>G on vitamin B12 cellular availability in end-stage renal disease patients.
Topics: Adult; Aged; Biological Availability; Cross-Sectional Studies; Cytosine; Female; Genotype; Guanine; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Osmolar Concentration; Transcobalamins; Vitamin B 12 | 2003 |
Impact of subclinical hypothyroidism on serum total homocysteine concentrations, the prevalence of coronary heart disease (CHD), and CHD risk factors in the New Mexico Elder Health Survey.
Topics: Aged; Aged, 80 and over; Coronary Disease; Creatinine; Fasting; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Hypothyroidism; Male; New Mexico; Prevalence; Risk Factors; Vitamin B 12 | 2003 |
Homocysteine and cognitive function in the Sacramento Area Latino Study on Aging.
Topics: Age Factors; Aged; Biomarkers; California; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Educational Status; Female; Hispanic or Latino; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Predictive Value of Tests; Risk Factors; Sex Factors; Vitamin B 12 | 2003 |
Plasma homocysteine concentration and blood pressure in young adult African Americans.
Topics: Adult; Age Factors; Biomarkers; Black or African American; Blood Glucose; Blood Pressure; Body Mass Index; Cross-Sectional Studies; Diastole; Female; Folic Acid; Homocysteine; Humans; Hypertension; Insulin; Male; Risk Factors; Sex Factors; Smoking; Statistics as Topic; Systole; Triglycerides; Vitamin B 12 | 2003 |
Creatine supplementation decreases homocysteine in an animal model of uremia.
Topics: Animals; Biometry; Creatine; Folic Acid; Homocysteine; Liver; Male; Nephrectomy; Osmolar Concentration; Rats; Rats, Wistar; Uremia; Vitamin B 12 | 2003 |
Reported symptoms and clinical findings in relation to serum cobalamin, folate, methylmalonic acid and total homocysteine among elderly Swedes: a population-based study.
Topics: Aged; Atrophy; Cohort Studies; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Male; Methylmalonic Acid; Mouth Diseases; Mouth Mucosa; Stomatitis; Tongue; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
[INFLUENCE OF VARIOUS METHYLATED SUBSTANCES SUPPLEMENTING SOJA FLOUR ON THE BIOSYNTHESIS OF TOTAL COBALAMINES AND VITAMINE B-12 BY STREPTOMYCES OLIVACEUS].
Topics: Alkaloids; Choline; Corrinoids; Culture Media; Cystine; Dietary Supplements; Flour; Glycine max; Homocysteine; Metabolism; Research; Streptomyces; Vitamin B 12; Vitamin B Complex | 1963 |
EFFECT OF VITAMIN B12 ANALOGUES ON METHIONINE FORMATION FROM N5-METHYLTETRAHYDROFOLIC ACID.
Topics: Carbon Isotopes; Corrinoids; Escherichia coli; Folic Acid; Homocysteine; Methionine; Pharmacology; Proteins; Research; Sulfhydryl Compounds; Vitamin B 12 | 1964 |
OROTIC ACID AND METABOLISM OF ONE CARBON UNIT: CONVERSION OF FOLIC ACID TO CITROVORUM FACTOR AND METHIONINE SYNTHESIS IN CHICK LIVER.
Topics: Animals; Carbon; Chickens; Folic Acid; Homocysteine; Leuconostoc; Leucovorin; Liver; Metabolism; Methionine; Orotic Acid; Poultry; Proteins; Research; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 1963 |
THE ROLE OF VITAMIN B12 IN METHYL TRANSFER TO HOMOCYSTEINE.
Topics: Chromatography; Escherichia coli; Flavin-Adenine Dinucleotide; Folic Acid; Homocysteine; Magnesium Sulfate; Mercaptoethanol; Methionine; Nucleosides; Pharmacology; Proteins; Research; Spectrophotometry; Sulfhydryl Compounds; Vitamin B 12 | 1964 |
METHYLCOBALAMIN AS A SOURCE OF THE METHYL GROUP OF METHIONINE.
Topics: Adenosine Triphosphate; Carbon Isotopes; Chromatography; Escherichia coli; Homocysteine; Methionine; Pharmacology; Proteins; Research; Vitamin B 12 | 1964 |
STUDIES ON METHYL TRANSFER FROM 5,6-DIMETHYLBENZIMIDAZOLYLCOBAMIDE METHYL (METHYL-B12) TO HOMOCYSTEINE.
Topics: Carbon Isotopes; Chromatography; Corrinoids; Escherichia coli; Homocysteine; Methionine; Research; Spectrophotometry; Transferases; Vitamin B 12 | 1964 |
ENZYMATIC SYNTHESIS OF THE METHYL GROUP OF METHIONINE. VII. ISOLATION OF A COBALAMIN-CONTAINING TRANSMETHYLASE (5-METHYLTETRAHYDRO-FOLATE-HOMOCYSTEINE) FROM MAMMALIAN LIVER.
Topics: Animals; Chromatography; Corrinoids; Flavin-Adenine Dinucleotide; Folic Acid; Glutamates; Homocysteine; Liver; Methionine; Methyltransferases; NAD; NADP; Protamines; Research; Swine; Transferases; Vitamin B 12 | 1964 |
THE ROLE OF VITAMIN B12 IN METHIONINE BIOSYNTHESIS IN AVIAN LIVER.
Topics: Amino Acids; Animals; Birds; Coenzymes; Corrinoids; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Homocysteine; Liver; Methionine; Poultry; Research; Transferases; Vitamin B 12 | 1964 |
VITAMIN B12 AND THE SYNTHESIS OF THE METHYL GROUPS OF CHOLINE IN OCHROMONAS MALHAMENSIS.
Topics: Alkylation; Carbon Isotopes; Choline; Coenzymes; Eukaryota; Formaldehyde; Formates; Homocysteine; Metabolism; Methionine; Ochromonas; Radiometry; Research; Tritium; Vitamin B 12 | 1964 |
STUDIES ON METHIONINE BIOSYNTHESIS. EFFECT OF ALKYLCOBAMIDE DERIVATIVES ON THE FORMATION OF HOLOENZYME.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Corrinoids; Dinitrophenols; Enzyme Inhibitors; Escherichia coli; Folic Acid; Holoenzymes; Homocysteine; Light; Metabolism; Methionine; Research; Transferases; Vitamin B 12 | 1965 |
THE FORMATION OF CH4 FROM N-5-METHYLTETRAHYDROFOLATE MONOGLUTAMATE BY CELL-FREE EXTRACTS OF METHANOBACILLUS OMELIANSKII.
Topics: Adenosine Triphosphate; Autoradiography; Bacteria; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography; Glutamates; Homocysteine; Methane; Methionine; Research; Spectrophotometry; Tetrahydrofolates; Vitamin B 12 | 1965 |
Cobalamin, folate, methylmalonic acid, homocysteine, and gastritis markers in dementia.
Topics: Biomarkers; Case-Control Studies; Dementia; Folic Acid; Gastritis; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Risk Factors; Vitamin B 12 | 2003 |
Fish oil supplementation of rats during pregnancy reduces adult disease risks in their offspring.
Topics: Animals; Blood Glucose; Caseins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dietary Proteins; Dietary Supplements; Female; Fish Oils; Folic Acid; Health Promotion; Homocysteine; Insulin; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Risk Factors; Triglycerides; Vitamin B 12 | 2003 |
Gonadotropin treatment increases homocysteine levels in idiopathic hypogonadotropic hypogonadism: an indirect effect mediated by changes in body composition.
Topics: Adult; Body Composition; Case-Control Studies; Creatinine; Folic Acid; Gonadotropins; Gonadotropins, Pituitary; Homocysteine; Humans; Hypogonadism; Male; Regression Analysis; Testosterone; Vitamin B 12 | 2003 |
Polyamine concentrations in the brain of vitamin B12-deficient rats.
Topics: Animals; Brain; Homocysteine; Liver; Male; Methionine; Neurons; Polyamines; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
The C677T mutation in methylenetetrahydrofolate reductase gene, plasma homocysteine concentration and the risk of coronary artery disease.
Topics: Adult; Aged; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Cysteine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Factors; Threonine; Vitamin B 12 | 2003 |
Homocysteine metabolism and B-vitamins in schizophrenic patients: low plasma folate as a possible independent risk factor for schizophrenia.
Topics: Adult; Base Pairing; DNA Mutational Analysis; Erythrocytes; Female; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Assessment; Schizophrenia; Schizophrenic Psychology; Vitamin B 12; Vitamin B 6 | 2003 |
Lowering plasma homocysteine.
Topics: Arteriosclerosis; Cardiovascular Diseases; Clinical Trials as Topic; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12 | 2003 |
Hyperhomocystinemia in children with inflammatory bowel disease.
Topics: Adolescent; Aging; Child; Child, Preschool; Colitis, Ulcerative; Crohn Disease; Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Methylenetetrahydrofolate Reductase (NADPH2); Reproducibility of Results; Risk Factors; Sensitivity and Specificity; Tetrahydrofolates; Thromboembolism; Vitamin B 12; von Willebrand Factor | 2003 |
Vitamin and homocysteine status of mothers and infants and the risk of nonsyndromic orofacial clefts.
Topics: Cleft Lip; Cleft Palate; Female; Folic Acid; Homocysteine; Humans; Infant; Mothers; Pyridoxal Phosphate; Risk Factors; Vitamin B 12; Vitamin B 6 | 2003 |
Routine determination of serum methylmalonic acid and plasma total homocysteine in Norway.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Clinical Laboratory Techniques; Creatinine; Female; Folic Acid; Homocysteine; Humans; Infant; Male; Methylmalonic Acid; Middle Aged; Norway; Sex Factors; Vitamin B 12 | 2003 |
Homocysteine status and polymorphisms of methylenetetrahydrofolate reductase are not associated with restenosis after stenting in coronary arteries.
Topics: Aged; Coronary Artery Disease; Coronary Restenosis; Female; Folic Acid; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Postoperative Complications; Prosthesis Implantation; Stents; Thrombosis; Treatment Outcome; Vitamin B 12 | 2003 |
Effect of homocysteine-lowering therapy on vascular endothelial function and exercise performance in coronary patients with hyperhomocysteinaemia.
Topics: Aged; Analysis of Variance; Blood Flow Velocity; Brachial Artery; Coronary Angiography; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Endothelium, Vascular; Exercise Test; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Prospective Studies; Ultrasonography; Vasodilation; Vitamin B 12; Vitamin B 6 | 2003 |
[Plasma homocysteine in human immunodeficiency virus infected patient].
Topics: Adult; Anti-HIV Agents; Arteriosclerosis; Biomarkers; Case-Control Studies; Female; Folic Acid; HIV Infections; Homocysteine; Humans; Hyperhomocysteinemia; Insulin Resistance; Male; P-Selectin; Risk Factors; Smoking; Vitamin B 12 | 2003 |
Cobalamin status and its biochemical markers methylmalonic acid and homocysteine in different age groups from 4 days to 19 years.
Topics: Adolescent; Adult; Biomarkers; Child; Child, Preschool; Cross-Sectional Studies; Female; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methylmalonic Acid; Reference Values; Vitamin B 12 | 2003 |
[Serum homocysteine in children and adolescents. Relation with family history of cardiovascular disease].
Topics: Adolescent; Cardiovascular Diseases; Child; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Lipoproteins; Male; Risk Factors; Vitamin B 12 | 2003 |
Moderate hyperhomocysteinaemia and immune activation in patients with rheumatoid arthritis.
Topics: Adult; Aged; Antigens, CD; Arthritis, Rheumatoid; Cysteine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Vitamin B 12 | 2003 |
Cardiovascular risk of young growth-hormone-deficient adolescents. Differences in growth-hormone-treated and untreated patients.
Topics: Adolescent; Cardiovascular Diseases; Child; Cholesterol, HDL; Cholesterol, LDL; Dietary Fats; Eating; Fasting; Female; Fibrinogen; Folic Acid; Homocysteine; Hormone Replacement Therapy; Human Growth Hormone; Humans; Male; Plasminogen Activator Inhibitor 1; Postprandial Period; Risk Assessment; Time Factors; Triglycerides; Vitamin B 12 | 2003 |
Homocysteine level and other biochemical parameters in cardiovascular disease patients with diabetes mellitus.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Diabetic Angiopathies; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Risk Factors; Vitamin B 12 | 2003 |
Null association between prostate cancer and serum folate, vitamin B(6), vitamin B(12), and homocysteine.
Topics: Aged; Case-Control Studies; Diet; Dietary Supplements; DNA Methylation; DNA Repair; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Prostatic Neoplasms; Risk Factors; Vitamin B 12; Vitamin B 6 | 2003 |
Abdominal aortic aneurysm and its correlation to plasma homocysteine, and vitamins.
Topics: Aged; Aortic Aneurysm, Abdominal; Case-Control Studies; Folic Acid; Homocysteine; Humans; Middle Aged; Vitamin B 12 | 2004 |
Functional vitamin B12 deficiency and determination of holotranscobalamin in populations at risk.
Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Diet, Vegetarian; Female; Folic Acid; Germany; Homocysteine; Humans; Kidney Diseases; Male; Methylmalonic Acid; Middle Aged; Risk; Syria; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Hyperhomocysteinemia and B-vitamin status after discontinuation of oral anticoagulation therapy in patients with a history of venous thromboembolism.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Retrospective Studies; Substance Withdrawal Syndrome; Thromboembolism; Vitamin B 12; Warfarin | 2003 |
Homocysteine increases during endurance exercise.
Topics: Adult; Exercise; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Physical Endurance; Reference Values; Sports; Time Factors; Vitamin B 12 | 2003 |
Comparison of the influence of volume-oriented training and high-intensity interval training on serum homocysteine and its cofactors in young, healthy swimmers.
Topics: Adolescent; Anthropometry; Exercise; Folic Acid; Heart Rate; Homocysteine; Humans; Methylmalonic Acid; Reference Values; Swimming; Time Factors; Vitamin B 12; Vitamin B 6 | 2003 |
Analysis of the transcobalamin II 776C>G (259P>R) single nucleotide polymorphism by denaturing HPLC in healthy elderly: associations with cobalamin, homocysteine and holo-transcobalamin II.
Topics: Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Gene Frequency; Genotype; Homocysteine; Humans; Middle Aged; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12 | 2003 |
The atherogenic effect of excess methionine intake.
Topics: Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Diet; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Mice; Models, Biological; Vitamin B 12; Vitamin B 6; Vitamin B Deficiency | 2003 |
Relation of homocysteine, folate, and vitamin B12 to bone mineral density of postmenopausal women.
Topics: Absorptiometry, Photon; Bone Density; Bone Diseases, Metabolic; Feeding Behavior; Female; Folic Acid; Homocysteine; Humans; Linear Models; Lumbar Vertebrae; Middle Aged; Osteoporosis, Postmenopausal; Patient Selection; Postmenopause; Risk Factors; Vitamin B 12 | 2003 |
Effects of the interaction between the C677T 5,10-methylenetetrahydrofolate reductase polymorphism and serum B vitamins on homocysteine levels in pregnant women.
Topics: Adult; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Pregnancy; Radioimmunoassay; Riboflavin; Vitamin B 12; Vitamin B 6 | 2004 |
Plasma total homocysteine concentrations in adults with growth hormone (GH) deficiency: effects of GH replacement.
Topics: Adult; Creatinine; Female; Folic Acid; Homocysteine; Hormone Replacement Therapy; Human Growth Hormone; Humans; Immunoradiometric Assay; Insulin; Insulin-Like Growth Factor I; Linear Models; Longitudinal Studies; Male; Thyroxine; Vitamin B 12 | 2003 |
Metabolic markers of cobalamin deficiency and cognitive function in normal older adults.
Topics: Aged; Citric Acid; Cognition; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Methylmalonic Acid; Statistics, Nonparametric; Vitamin B 12 | 2004 |
Vitamin B12 and folate deficiency in later life.
Topics: Age Factors; Aged; Aged, 80 and over; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Institutionalization; Prevalence; United Kingdom; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
Cobalamin (vitamin B12) metabolism during pregnancy.
Topics: Adult; Anemia, Megaloblastic; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Vitamin B 12 | 2004 |
Vitamin B12 status in the elderly as judged by available biochemical markers.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12; Vitamin B 6 | 2004 |
Plasma homocysteine levels in patients with early coronary artery stenosis and high risk factors.
Topics: Adult; Aged; Coronary Stenosis; Diabetes Complications; Folic Acid; Homocysteine; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Risk Factors; Smoking; Vitamin B 12 | 2003 |
[Hyperhomocysteinemia and deep-vein thrombosis].
Topics: Adult; Aged; Aged, 80 and over; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Restriction Fragment Length; Venous Thrombosis; Vitamin B 12 | 2003 |
Plasma homocysteine concentrations in adolescents with subclinical hypothyroidism.
Topics: Adolescent; Cholesterol; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypothyroidism; Isoantibodies; Kidney; Kidney Function Tests; Thyroiditis, Autoimmune; Thyrotropin; Thyroxine; Triiodothyronine; Vitamin B 12 | 2003 |
Folate, homocysteine levels, methylenetetrahydrofolate reductase (MTHFR) 677C --> T variant, and the risk of myocardial infarction in young women: effect of female hormones on homocysteine levels.
Topics: Adolescent; Adult; Case-Control Studies; Contraceptives, Oral; Female; Folic Acid; Genetic Variation; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Infarction; Risk Factors; Vitamin B 12 | 2004 |
[A case of subacute combined degeneration with normal serum vitamin B12 level].
Topics: Adult; Anemia, Megaloblastic; Female; Homocysteine; Humans; Neurodegenerative Diseases; Pancytopenia; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Methylenetetrahydrofolate reductase (MTHFR) c677t gene variant modulates the homocysteine folate correlation in a mild folate-deficient population.
Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Vitamin B 12 | 2004 |
Hematological parameters and cobalamin status in infants born to smoking mothers.
Topics: Adult; Birth Weight; Erythrocyte Count; Female; Folic Acid; Gestational Age; Hemoglobins; Homocysteine; Humans; Infant; Infant, Newborn; Logistic Models; Maternal-Fetal Exchange; Methylmalonic Acid; Pregnancy; Smoking; Vitamin B 12 | 2004 |
Elevated levels of plasma homocysteine in hypertensive patients with diabetes mellitus.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Blood Glucose; Blood Pressure; Diabetes Mellitus; Diastole; Female; Folic Acid; Homocysteine; Humans; Hypertension; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Systole; Vitamin B 12 | 2003 |
Hyperhomocysteinemia and oxidative stress in hemodialysis: effects of supplementation with folic acid.
Topics: Ascorbic Acid; Dietary Supplements; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipid Peroxidation; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Proteins; Renal Dialysis; Vitamin B 12; Vitamin E | 2003 |
Low initial vitamin B12 levels in Helicobacter pylori--positive patients on chronic hemodialysis.
Topics: Anemia, Macrocytic; Female; Folic Acid; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Prevalence; Renal Dialysis; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
Plasma homocysteine after insulin infusion in type II diabetic patients with and without methionine intolerance.
Topics: Blood Glucose; Cysteine; Diabetes Mellitus, Type 2; DNA; Female; Folic Acid; Glucose Clamp Technique; Homocysteine; Humans; Hyperhomocysteinemia; Insulin; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymerase Chain Reaction; Vitamin B 12; Vitamin B 6 | 2004 |
The challenge of stroke prevention.
Topics: Antibodies, Antiphospholipid; Folic Acid; Homocysteine; Humans; Risk Factors; Risk Reduction Behavior; Stroke; Vitamin B 12; Vitamin B 6 | 2004 |
Laxative treatment elevates plasma homocysteine: a study on a population-based Swedish sample of old people.
Topics: Aged; Aged, 80 and over; Cathartics; Cohort Studies; Constipation; Drug Prescriptions; Female; Folic Acid; Geriatric Assessment; Homocysteine; Humans; Lactulose; Male; Sweden; Vitamin B 12 | 2004 |
[Study on the relationship of MTHFR polymorphisms with unexplained recurrent spontaneous abortion].
Topics: Abortion, Habitual; Adult; Alleles; China; DNA Mutational Analysis; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Vitamin B 12 | 2004 |
Diet score is associated with plasma homocysteine in a healthy institutionalised elderly population.
Topics: Aged; Aged, 80 and over; Cohort Studies; Cross-Sectional Studies; Diet; Female; Folic Acid; Homes for the Aged; Homocysteine; Humans; Male; Middle Aged; Nursing Homes; Prospective Studies; Riboflavin; Spain; Vitamin B 12 | 2003 |
[Influence of biochemical and genetic factors on homocysteine concentrations].
Topics: Adolescent; Child; Child, Preschool; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12 | 2004 |
Effect of vitamin B12 on homocysteine plasma concentration in hemodialysis patients.
Topics: Aged; Folic Acid; Homocysteine; Humans; Middle Aged; Renal Dialysis; Uremia; Vitamin B 12 | 2004 |
Hyperhomocysteinaemia & folic acid supplementation in patients with high risk of coronary artery disease.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Coronary Artery Disease; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Male; Microscopy, Fluorescence; Middle Aged; Risk Factors; Time Factors; Vitamin B 12 | 2004 |
[Assessment of medical students' intake of antioxidants and vitamins essential for homocysteine metabolism].
Topics: Adult; Antioxidants; Ascorbic Acid; Diet; Diet Surveys; Feeding Behavior; Female; Folic Acid; Food Preferences; Health Behavior; Health Education; Homocysteine; Humans; Male; Nutrition Surveys; Poland; Students, Medical; Vitamin B 12; Vitamin B 6; Vitamin E; Vitamins | 2002 |
Serum total homocysteine levels and the prevalence of folic acid deficiency and C677T mutation at the MTHFR gene in an indigenous population of Amazonia: the relationship of homocysteine with other cardiovascular risk factors.
Topics: Adult; Brazil; Cardiovascular Diseases; Female; Folic Acid Deficiency; Health Status Indicators; Homocysteine; Humans; Hyperhomocysteinemia; Indians, South American; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Risk Factors; Sex Factors; Smoking; Vitamin B 12 | 2004 |
Serum total homocysteine levels, folate, and B-vitamins intake and coronary heart disease risk factors among tri-ethnic college students.
Topics: Adult; Black or African American; Coronary Disease; Female; Florida; Folic Acid; Hispanic or Latino; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Risk Factors; Sex Factors; Smoking; Universities; Vitamin B 12; Vitamin B 6; White People | 2004 |
Risk factors for heart disease.
Topics: Brazil; Cardiovascular Diseases; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Indians, South American; Risk Factors; Vitamin B 12 | 2004 |
Eat right and exercise for lower homocysteine levels and less chance of heart disease.
Topics: Adult; Age Factors; Coronary Disease; Exercise; Feeding Behavior; Female; Florida; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Smoking; Vitamin B 12; Vitamin B 6 | 2004 |
Methionine metabolism in plants: chloroplasts are autonomous for de novo methionine synthesis and can import S-adenosylmethionine from the cytosol.
Topics: Arabidopsis; Blotting, Western; Chloroplasts; Cloning, Molecular; Cytosol; Diffusion; DNA, Complementary; Dose-Response Relationship, Drug; Escherichia coli; Green Fluorescent Proteins; Homocysteine; Immunoblotting; Kinetics; Luminescent Proteins; Methionine; Mitochondria; Models, Biological; Molecular Sequence Data; Phylogeny; Pisum sativum; Plastids; Protein Isoforms; S-Adenosylmethionine; Time Factors; Vitamin B 12 | 2004 |
Perinatal outcome prediction by maternal homocysteine and uterine artery Doppler velocimetry.
Topics: Adult; Arteries; Blood Flow Velocity; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Laser-Doppler Flowmetry; Predictive Value of Tests; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Sensitivity and Specificity; Ultrasonography; Uterus; Vitamin B 12 | 2004 |
Comparative analysis of serum homocysteine, folic acid and Vitamin B12 levels in patients with noise-induced hearing loss.
Topics: Adult; Audiometry, Pure-Tone; Case-Control Studies; Folic Acid; Hearing Loss, Noise-Induced; Homocysteine; Humans; Male; Surveys and Questionnaires; Vitamin B 12 | 2004 |
Hyperhomocysteinemia in patients with Behçet's disease: is it due to inflammation or therapy?
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Behcet Syndrome; C-Reactive Protein; Colchicine; Drug Therapy, Combination; Eye Diseases; Female; Folic Acid; Glucocorticoids; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Male; Thrombosis; Vitamin B 12 | 2005 |
Young stroke and basal plasma and post-methionine load homocysteine and cysteine levels 1 year after the acute event: do plasma folates make the difference?
Topics: Adult; Case-Control Studies; Cysteine; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Methionine; Middle Aged; Stroke; Time Factors; Vitamin B 12 | 2004 |
High prevalence of metabolic syndrome among young women with nonfatal myocardial infarction.
Topics: Adult; Antibodies, Anticardiolipin; beta 2-Glycoprotein I; Biomarkers; C-Reactive Protein; Case-Control Studies; Chi-Square Distribution; Female; Glycoproteins; Homocysteine; Humans; Massachusetts; Metabolic Syndrome; Middle Aged; Myocardial Infarction; Obesity; Plasminogen Activator Inhibitor 1; Predictive Value of Tests; Prevalence; Prothrombin; Risk Factors; Serum Amyloid A Protein; Smoking; Surveys and Questionnaires; Vitamin B 12 | 2004 |
Homocysteine and methylenetetrahydrofolate reductase polymorphism in Alzheimer's disease.
Topics: Age Factors; Aged; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Case-Control Studies; Confidence Intervals; Female; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Odds Ratio; Polymorphism, Genetic; Pteroylpolyglutamic Acids; Regression Analysis; Statistics, Nonparametric; Transcobalamins; Vitamin B 12 | 2004 |
Analysis of hippocampal atrophy in alcoholic patients by a Kohonen feature map.
Topics: Adult; Aged; Alcohol-Induced Disorders, Nervous System; Atrophy; Avitaminosis; Data Interpretation, Statistical; Ethanol; Female; Folic Acid; Hippocampus; Homocysteine; Humans; Linear Models; Male; Middle Aged; Neural Networks, Computer; Reference Values; Sex Factors; Vitamin B 12; Vitamin B 6 | 2004 |
Effects of TCN2 776C>G on vitamin B, folate, and total homocysteine levels in kidney transplant patients.
Topics: Adult; Aged; Alleles; Cross-Sectional Studies; Female; Folic Acid; Gene Frequency; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Kidney Transplantation; Male; Middle Aged; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12 | 2004 |
Homocysteine and folic acid are inversely related in black women with preeclampsia.
Topics: Adolescent; Adult; Arteriosclerosis; Black People; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Maternal Age; Pennsylvania; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12; White People | 2004 |
[Relations of methionine synthase gene variation with congenital heart disease].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Child; Child, Preschool; Female; Folic Acid; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glutathione; Heart Defects, Congenital; Heart Septal Defects; Homocysteine; Humans; Infant; Male; Polymorphism, Genetic; Vitamin B 12 | 2004 |
Homocysteine in a multi-ethnic sample of school-age children.
Topics: Adolescent; Cardiovascular Diseases; Child; Diet; Ethnicity; Fasting; Female; Folic Acid; Hispanic or Latino; Homocysteine; Humans; Indians, North American; Male; Nutrition Policy; School Health Services; Vitamin B 12; Vitamin B 6; White People | 2004 |
Effects of paradoxical sleep deprivation on blood parameters associated with cardiovascular risk in aged rats.
Topics: Age Factors; Aging; Animals; Blood Viscosity; Cardiovascular Diseases; Cholesterol; Folic Acid; Homocysteine; Lipoproteins; Male; Rats; Rats, Wistar; Risk Factors; Sleep Deprivation; Triglycerides; Vitamin B 12 | 2004 |
Serum levels of folate, vitamin B12 and homocysteine in complete hydatidiform mole.
Topics: Adult; Biomarkers; Case-Control Studies; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hydatidiform Mole; Luminescent Measurements; Pregnancy; Vitamin B 12 | 2004 |
Methionine synthase reductase MTRR 66A > G has no effect on total homocysteine, folate, and Vitamin B12 concentrations in renal transplant patients.
Topics: Adult; Analysis of Variance; Base Sequence; Cross-Sectional Studies; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Expression; Graft Rejection; Graft Survival; Homocysteine; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Molecular Sequence Data; Multivariate Analysis; Mutation; Polymerase Chain Reaction; Prognosis; Vitamin B 12 | 2004 |
Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms, plasma homocysteine, folate, and vitamin B12 levels and the extent of coronary artery disease.
Topics: Aged; Biomarkers; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; DNA Primers; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Severity of Illness Index; Vitamin B 12 | 2004 |
Elevated plasma homocysteine levels in gestational diabetes mellitus.
Topics: Adult; Blood Glucose; Case-Control Studies; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes, Gestational; Female; Folic Acid; Gestational Age; Glucose Tolerance Test; Homocysteine; Humans; Pregnancy; Prospective Studies; Triglycerides; Turkey; Vitamin B 12 | 2004 |
Homocysteine and cobalamin status in German vegans.
Topics: Adult; Aged; Aged, 80 and over; Body Mass Index; Cross-Sectional Studies; Diet, Vegetarian; Female; Folic Acid; Germany; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Prevalence; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
Plasma homocysteine and immune activation in patients with malignant melanoma undergoing treatment with IFN-alpha.
Topics: Adult; Aged; Antineoplastic Agents; Female; Folic Acid; Homocysteine; Humans; Interferon alpha-2; Interferon-alpha; Kynurenine; Macrophage Activation; Male; Melanoma; Middle Aged; Neopterin; Predictive Value of Tests; Recombinant Proteins; Tryptophan; Vitamin B 12 | 2004 |
Homocysteine and progression of coronary artery disease.
Topics: Adult; Blood Glucose; Coronary Artery Disease; Disease Progression; Folic Acid; Homocysteine; Humans; Hypertension; Lipids; Male; Middle Aged; Myocardial Infarction; Obesity; Research Design; Risk Factors; Smoking; Vitamin B 12 | 2004 |
Fibrate treatment and prevalence risk of mild hyperhomocysteinaemia in clinical coronary heart disease patients.
Topics: Case-Control Studies; Coronary Disease; Creatinine; Female; Folic Acid; Genotype; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Hypolipidemic Agents; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Prevalence; Retrospective Studies; Vitamin B 12 | 2004 |
Diet, serum homocysteine levels and ischaemic heart disease in a Mediterranean population.
Topics: Adult; Aged; Case-Control Studies; Cholesterol; Creatinine; Diet; Female; Folic Acid; Greece; Homocysteine; Humans; Male; Middle Aged; Myocardial Ischemia; Vitamin B 12 | 2004 |
Plasma homocysteine levels and risk of Alzheimer disease.
Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Cohort Studies; Comorbidity; Confounding Factors, Epidemiologic; Cross-Sectional Studies; Cysteine; Dementia; Diabetes Mellitus; Ethnicity; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Memory; Neuropsychological Tests; New York City; Prevalence; Risk Factors; Sampling Studies; Stroke; Vitamin B 12; Vitamin B 6 | 2004 |
Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Cognition Disorders; Cross-Sectional Studies; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Odds Ratio; Risk Factors; Switzerland; Vitamin B 12 | 2004 |
Polymorphisms in the methylenetetrahydrofolate reductase and methionine synthase reductase genes and homocysteine levels in Brazilian children.
Topics: Brazil; Child; Child, Preschool; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors; Vitamin B 12 | 2004 |
Serum selenium is associated with plasma homocysteine concentrations in elderly humans.
Topics: Aged; Aged, 80 and over; Body Mass Index; Cardiovascular Diseases; Cross-Sectional Studies; Energy Intake; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Selenium; Vitamin B 12 | 2004 |
Plasma trace elements, vitamin B12, folate, and homocysteine levels in cirrhotic patients compared to healthy controls.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Health; Homocysteine; Humans; Liver Cirrhosis; Male; Middle Aged; Trace Elements; Vitamin B 12 | 2004 |
Low grade inflammation in juvenile obesity and type 1 diabetes associated with early signs of atherosclerosis.
Topics: Adolescent; Arteriosclerosis; Body Mass Index; C-Peptide; C-Reactive Protein; Carotid Artery, Common; Child; Diabetes Mellitus, Type 1; Female; Folic Acid; Homocysteine; Humans; Inflammation; Leptin; Male; Obesity; Receptors, Interleukin-2; Tunica Intima; Vitamin B 12 | 2004 |
Prevention of homocysteine thiolactone induced atherogenesis in rats.
Topics: Animals; Aorta, Thoracic; Arterial Occlusive Diseases; Arteries; Arteriosclerosis; Cobamides; Female; Food; Homocysteine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Propylene Glycol; Rats; Tissue Fixation; Tretinoin; Vitamin B 12; Weight Gain | 2002 |
Longitudinal change in plasma total homocysteine during pregnancy and postpartum in Brazilian women and its relation with folate status and other factors.
Topics: Brazil; Chromatography, High Pressure Liquid; Diet; Dietary Supplements; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Iron; Longitudinal Studies; Nutritional Status; Postpartum Period; Pregnancy; Socioeconomic Factors; Transferrin; Vitamin B 12 | 2004 |
Effect of age on plasma homocysteine concentrations in young and elderly subjects considering serum vitamin concentrations and different lifestyle factors.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Coffee; Female; Folic Acid; Germany; Homocysteine; Humans; Life Style; Linear Models; Longitudinal Studies; Male; Methionine; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Sex Characteristics; Smoking; Tea; Vitamin B 12 | 2004 |
Metabolic effects and the methylenetetrahydrofolate reductase (MTHFR) polymorphism associated with neural tube defects in southern Brazil.
Topics: Adolescent; Adult; Brazil; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Infant; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Polymorphism, Genetic; Vitamin B 12 | 2004 |
Association between serum homocysteine, folate and B12 concentration with coronary artery disease in Thai patients.
Topics: Coronary Disease; Cross-Sectional Studies; Female; Homocysteine; Humans; Logistic Models; Male; Seroepidemiologic Studies; Thailand; Vitamin B 12 | 2004 |
Folate intake and risk of Parkinson's disease.
Topics: Adult; Cohort Studies; Diet; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Parkinson Disease; Prospective Studies; Reference Values; Risk Factors; United States; Vitamin B 12; Vitamin B 6 | 2004 |
The cblD defect causes either isolated or combined deficiency of methylcobalamin and adenosylcobalamin synthesis.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Alkyl and Aryl Transferases; Child; Child, Preschool; Cobamides; DNA, Complementary; Fibroblasts; Genetic Complementation Test; Homocysteine; Homocystinuria; Humans; Male; Methionine; Methylmalonyl-CoA Mutase; Models, Biological; Mutation; Phenotype; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
Marginal maternal vitamin B12 status increases the risk of offspring with spina bifida.
Topics: Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Infant; Male; Pregnancy; Risk Assessment; Risk Factors; Spinal Dysraphism; Vitamin B 12; Vitamin B 6 | 2004 |
The administration of a multivitamin/mineral fortified dairy product improves folate status and reduces plasma homocysteine concentration in women of reproductive age.
Topics: Adult; Dairy Products; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Minerals; Patient Compliance; Vitamin B 12; Vitamins | 2004 |
Increasing production of homocysteine and neopterin and degradation of tryptophan with older age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Dioxygenases; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Macrophages; Male; Middle Aged; Neopterin; T-Lymphocytes; Time Factors; Tryptophan; Vitamin B 12 | 2004 |
Abnormal folic acid-homocysteine metabolism as maternal risk factors for Down syndrome in Japan.
Topics: Adult; Down Syndrome; Female; Folic Acid; Homocysteine; Humans; Japan; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Risk Factors; Vitamin B 12; Vitamin B 6 | 2004 |
Homocysteine increases methionine synthase mRNA level in Caco-2 cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenocarcinoma; Caco-2 Cells; Gene Expression Regulation, Neoplastic; Homocysteine; Humans; Methionine; RNA, Messenger; Transcription, Genetic; Up-Regulation; Vitamin B 12 | 2004 |
Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Arabidopsis; Binding Sites; Cations; Crystallography, X-Ray; Cysteine; Escherichia coli; Folic Acid; Fourier Analysis; Histidine; Homocysteine; Methionine; Methyltransferases; Models, Molecular; Plasmids; Protein Conformation; Protein Structure, Tertiary; Sulfur; Tetrahydrofolates; Vitamin B 12; Zinc | 2004 |
Folate, homocysteine, and negative symptoms in schizophrenia.
Topics: Adult; Ambulatory Care; Basal Ganglia Diseases; Diet; Female; Folic Acid; Glutamate Carboxypeptidase II; Homocysteine; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Smoking; Vitamin B 12 | 2004 |
Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in vivo.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Colorectal Neoplasms; DNA Damage; DNA Methylation; Erythrocytes; Female; Folic Acid; Genetic Carrier Screening; Genetic Variation; Genotype; Homocysteine; Homozygote; Humans; Isoenzymes; Lymphocytes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk; Scotland; Tetrahydrofolates; Uracil; Vitamin B 12 | 2004 |
Case-control study of multiple chemical sensitivity, comparing haematology, biochemistry, vitamins and serum volatile organic compound measures.
Topics: Adult; Alkanes; Benzene Derivatives; Case-Control Studies; Chloroform; Dietary Supplements; Dose-Response Relationship, Drug; Environmental Exposure; Female; Folic Acid; Hematologic Tests; Hemoglobins; Homocysteine; Humans; Hydrocarbons; Middle Aged; Multiple Chemical Sensitivity; Vitamin B 12; Vitamin B 6; Vitamins | 2004 |
Folate and cobalamin synergistically decrease the risk of high plasma homocysteine in a nonsupplemented elderly institutionalized population.
Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Diet; Drug Synergism; Female; Folic Acid; Homes for the Aged; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutritional Status; Risk Factors; Vitamin B 12; Vitamin B Complex | 2004 |
Plasma folate concentrations are associated with depressive symptoms in elderly Latina women despite folic acid fortification.
Topics: Acculturation; Aged; Aging; California; Cross-Sectional Studies; Depression; Diet; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Hispanic or Latino; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Sex Factors; Vitamin B 12 | 2004 |
Cobalamin-responsive disorders in the ambulatory care setting: unreliability of cobalamin, methylmalonic acid, and homocysteine testing.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Health Maintenance Organizations; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Reproducibility of Results; Retrospective Studies; Treatment Outcome; Treatment Refusal; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Plasma folate as marker of folate status in epidemiological studies: the European Investigation into Cancer and Nutrition (EPIC)-Potsdam study.
Topics: Adult; Age Factors; Biomarkers; Body Mass Index; Cross-Sectional Studies; Diet; Dietary Supplements; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Life Style; Male; Middle Aged; Polymorphism, Genetic; Pyridoxal Phosphate; Pyridoxine; Vitamin B 12 | 2004 |
Negative association between circulating total homocysteine and proinflammatory chemokines MCP-1 and RANTES in prepubertal lean, but not in obese, children.
Topics: Arteriosclerosis; Blood Glucose; Body Mass Index; Body Weight; Chemokine CCL2; Chemokine CCL5; Chemotaxis, Leukocyte; Child; Cholesterol, HDL; Data Interpretation, Statistical; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Insulin; Male; Obesity; Puberty; Sex; Thinness; Triglycerides; Vitamin B 12 | 2004 |
A population-based intervention study on elevated serum levels of methylmalonic acid and total homocysteine in elderly people: results after 36 months of follow-up.
Topics: Aged; Cohort Studies; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Longitudinal Studies; Male; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
Homocysteine, vitamin B12 and folate in vascular dementia and in Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Case-Control Studies; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neurons; Nutritional Status; Oxidative Stress; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
Homocysteine effect on protein degradation rates.
Topics: Aged; Aged, 80 and over; Animals; Female; Folic Acid; Homocysteine; Humans; Male; Neutrophils; Proteins; Rats; Vitamin B 12; Vitamin B 6 | 2004 |
Plasma folate, vitamin B12, and homocysteine and prostate cancer risk: a prospective study.
Topics: Adult; Aged; Bone Neoplasms; Case-Control Studies; Folic Acid; Homocysteine; Humans; Lymphatic Metastasis; Male; Middle Aged; Prospective Studies; Prostatic Neoplasms; Risk Factors; Sweden; Vitamin B 12 | 2005 |
Plasma homocysteine, MTHFR C677T, CBS 844ins68bp, and MTHFD1 G1958A polymorphisms in spontaneous cervical artery dissections.
Topics: Adult; Analysis of Variance; Case-Control Studies; Chi-Square Distribution; Cystathionine beta-Synthase; DNA Mutational Analysis; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Pteroylpolyglutamic Acids; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Statistics, Nonparametric; Vertebral Artery Dissection; Vitamin B 12; Vitamin B 6 | 2004 |
Methionine synthase reductase 66A->G polymorphism is associated with increased plasma homocysteine concentration when combined with the homozygous methylenetetrahydrofolate reductase 677C->T variant.
Topics: Adult; Dietary Supplements; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Homozygote; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Vitamin B 12 | 2004 |
Effect of metformin on plasma homocysteine, vitamin B12 and folic acid: a cross-sectional study in patients with type 2 diabetes mellitus.
Topics: Adult; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Vitamin B 12 | 2004 |
Response of homocysteine, cystathionine, and methylmalonic acid to vitamin treatment in dialysis patients.
Topics: Aged; Aged, 80 and over; Cystathionine; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylmalonic Acid; Middle Aged; Renal Dialysis; Vitamin B 12; Vitamin B 6 | 2005 |
Changes of homocysteine levels and arterial endothelial function in patients with high risk of coronary artery disease after 6-month folic acid supplementation.
Topics: Aged; Arteries; Chromatography, High Pressure Liquid; Coronary Artery Disease; Dietary Supplements; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Time; Treatment Outcome; Vitamin B 12 | 2004 |
Plasma homocysteine, vitamin B12 and folate in Alzheimer's patients and healthy Arabs in Israel.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arabs; Case-Control Studies; Confidence Intervals; Female; Folic Acid; Homocysteine; Humans; Israel; Male; Odds Ratio; Vitamin B 12 | 2004 |
Betaine and folate status as cooperative determinants of plasma homocysteine in humans.
Topics: Adult; Aged; Betaine; Choline; Creatinine; Dose-Response Relationship, Drug; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Sarcosine; Vitamin B 12; Vitamin B 6 | 2005 |
Alteration of homocysteine catabolism in pre-eclampsia, HELLP syndrome and placental insufficiency.
Topics: Cystathionine; Cystatin C; Cystatins; Female; Folic Acid; HELLP Syndrome; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Methylmalonic Acid; Oxidative Stress; Placental Insufficiency; Pre-Eclampsia; Pregnancy; Severity of Illness Index; Uric Acid; Vitamin B 12; Vitamin B 6 | 2004 |
Folate, homocysteine, and cobalamin status in patients with rheumatoid arthritis treated with methotrexate, and the effect of low dose folic acid supplement.
Topics: Arthritis, Rheumatoid; Biomarkers; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Methotrexate; Probability; Prospective Studies; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Single-Blind Method; Treatment Outcome; Vitamin B 12 | 2004 |
The risk of folate and vitamin B(12) deficiencies associated with hyperhomocysteinemia among pregnant women.
Topics: Adolescent; Adult; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Korea; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
Contribution of the MTHFR gene to the causal pathway for depression, anxiety and cognitive impairment in later life.
Topics: Aged; Aged, 80 and over; Aging; Anxiety; Chi-Square Distribution; Cognition Disorders; Cross-Sectional Studies; Depression; DNA Mutational Analysis; Female; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neuropsychological Tests; Personality Inventory; Pteroylpolyglutamic Acids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vitamin B 12 | 2005 |
Frequent consumption of milk, yogurt, cold breakfast cereals, peppers, and cruciferous vegetables and intakes of dietary folate and riboflavin but not vitamins B-12 and B-6 are inversely associated with serum total homocysteine concentrations in the US po
Topics: Adult; Animals; Brassicaceae; Capsicum; Cross-Sectional Studies; Dairy Products; Edible Grain; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Milk; Multivariate Analysis; Nutrition Surveys; Riboflavin; Surveys and Questionnaires; United States; Vegetables; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Yogurt | 2004 |
Homocysteine concentrations in adults with trisomy 21: effect of B vitamins and genetic polymorphisms.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Administration, Oral; Adolescent; Adult; Case-Control Studies; Cystathionine beta-Synthase; Dietary Supplements; Down Syndrome; Drug Synergism; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Homocysteine; Homozygote; Humans; Male; Membrane Transport Proteins; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Reduced Folate Carrier Protein; Vitamin B 12; Vitamin B 6 | 2004 |
Association between depressive symptoms and serum concentrations of homocysteine in men: a population study.
Topics: Cohort Studies; Cross-Sectional Studies; Depression; Finland; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Psychometrics; Surveys and Questionnaires; Vitamin B 12 | 2004 |
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2004 |
Serum levels of folate, homocysteine, and vitamin B12 in head and neck squamous cell carcinoma and in laryngeal leukoplakia.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Female; Folic Acid; Head and Neck Neoplasms; Homocysteine; Humans; Laryngeal Neoplasms; Leukoplakia; Male; Middle Aged; Prognosis; Reference Values; Risk Assessment; Sensitivity and Specificity; Vitamin B 12 | 2005 |
Cellular uptake of vitamin B12 in patients with chronic renal failure.
Topics: Adult; Aged; Cells, Cultured; Cystathionine; Female; Homocysteine; Humans; Kidney Failure, Chronic; Leukocytes, Mononuclear; Male; Methylmalonic Acid; Middle Aged; Vitamin B 12 | 2005 |
Plasma folate and homocysteine levels may be related to interictal "schizophrenia-like" psychosis in patients with epilepsy.
Topics: Adult; Electroencephalography; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Schizophrenic Psychology; Vitamin B 12 | 2005 |
Plasma homocysteine levels in polycystic ovary syndrome and congenital adrenal hyperplasia.
Topics: Adrenal Hyperplasia, Congenital; Adult; Blood Glucose; Cholesterol; Estradiol; Female; Follicle Stimulating Hormone; Homocysteine; Humans; Insulin Resistance; Luteinizing Hormone; Polycystic Ovary Syndrome; Progesterone; Statistics, Nonparametric; Testosterone; Thyrotropin; Thyroxine; Vitamin B 12 | 2004 |
Influence of serum folic acid levels on plasma homocysteine concentrations in patients with rheumatoid arthritis.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Methotrexate; Middle Aged; Statistics, Nonparametric; Vitamin B 12; Vitamin B Complex | 2006 |
Homocysteine, antiphospholipid antibodies and risk of thrombosis in patients with systemic lupus erythematosus.
Topics: Adult; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Cholesterol; Creatinine; Female; Folic Acid; Homocysteine; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Risk Factors; Thrombosis; Vitamin B 12 | 2004 |
Effects of dietary supplements of folic acid and rumen-protected methionine on lactational performance and folate metabolism of dairy cows.
Topics: Animals; Cattle; Cysteine; Diet; Dietary Supplements; Female; Folic Acid; Hemoglobins; Homocysteine; Kinetics; Lactation; Methionine; Milk; Rumen; Vitamin B 12 | 2005 |
Effects of intramuscular injections of vitamin B12 on lactation performance of dairy cows fed dietary supplements of folic acid and rumen-protected methionine.
Topics: Animals; Cattle; Cysteine; Diet; Dietary Supplements; Eating; Female; Folic Acid; Homocysteine; Injections, Intramuscular; Lactation; Methionine; Methylmalonic Acid; Milk; Parity; Rumen; Vitamin B 12 | 2005 |
Serum lipid profiles and homocysteine levels in adults with stroke or myocardial infarction in the town of Gombe in northern Nigeria.
Topics: Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Female; Folic Acid; Homocysteine; Humans; Hypertension; Lipids; Male; Middle Aged; Myocardial Infarction; Nigeria; Risk Factors; Stroke; Triglycerides; Vitamin B 12 | 2004 |
Risk factors for cardiovascular disease and diet of urban and rural dwellers in northern Nigeria.
Topics: Adult; Aged; Cardiovascular Diseases; Diet; Female; Folic Acid; Homocysteine; Humans; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Nigeria; Risk Factors; Rural Population; Triglycerides; Urban Population; Vitamin B 12 | 2004 |
Homocysteine and its nutritional determinants in two ethnic groups of Slovakia.
Topics: Adult; Biomarkers; Case-Control Studies; Feeding Behavior; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Middle Aged; Nutrition Surveys; Slovakia; Vitamin B 12; Vitamin B 6 | 2004 |
Distribution of 5,10-methylenetetrahydrofolate reductase (C667T) polymorphism and its association with red blood cell 5-methyltetrahydrofolate in the healthy Iranians.
Topics: Analysis of Variance; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Iran; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutritional Requirements; Polymorphism, Genetic; Tetrahydrofolates; Vitamin B 12 | 2005 |
Effects of oral contraceptives and hormone replacement therapy on markers of cobalamin status.
Topics: Adolescent; Adult; Aged; Contraceptives, Oral, Combined; Cross-Sectional Studies; Estrogen Replacement Therapy; Female; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12 | 2005 |
Stroke and recurrent pregnancy loss due to hyperhomocysteinaemia.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Abortion, Habitual; Brain; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Infarction, Middle Cerebral Artery; Middle Aged; Mutation; Platelet Aggregation Inhibitors; Pregnancy; Stroke; Treatment Outcome; Vitamin B 12 | 2005 |
Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging.
Topics: Aged; Aging; Alzheimer Disease; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Longitudinal Studies; Male; Risk Factors; Vitamin B 12; Vitamin B 6 | 2005 |
Cobalamin deficiency in elderly patients.
Topics: Aged; Algorithms; Canada; Folic Acid; Food, Fortified; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
[Study of serum Hcy and polymorphisms of Hcy metabolic enzymes in 192 families affected by congenital heart disease].
Topics: Female; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Vitamin B 12 | 2005 |
Serum folate and homocysteine levels in obese females with non-alcoholic fatty liver.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Bariatrics; Body Mass Index; Case-Control Studies; Fatty Liver; Female; Folic Acid; Homocysteine; Humans; Liver Function Tests; Obesity, Morbid; Vitamin B 12 | 2005 |
Folic acid supplementation can reduce the endothelial damage in rat brain microvasculature due to hyperhomocysteinemia.
Topics: Animals; Cerebrovascular Circulation; Dietary Supplements; Disease Models, Animal; Endothelium, Vascular; Energy Intake; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Microcirculation; Rats; Rats, Sprague-Dawley; Reference Values; Thiobarbituric Acid Reactive Substances; Vitamin B 12; Weight Gain | 2005 |
Homocysteine and fracture prevention.
Topics: Dietary Supplements; Folic Acid; Hip Fractures; Homocysteine; Humans; Risk Factors; Stroke; Vitamin B 12 | 2005 |
Low erythrocyte folate, but not plasma vitamin B-12 or homocysteine,is associated with dementia in elderly Latinos.
Topics: Aged; Aged, 80 and over; California; Cohort Studies; Dementia; Erythrocytes; Female; Folic Acid; Hispanic or Latino; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Vitamin B 12 | 2005 |
Elevation of plasma homocysteine in natural menopause can not be explained by a lack of vitamin coenzyme availability: relevance to the risk of cardiovascular disease.
Topics: Adult; Cardiovascular Diseases; Coenzymes; Diet; Estrogens; Female; Folic Acid; Homocysteine; Humans; Menopause; Middle Aged; Risk Factors; Vitamin B 12; Vitamin B 6 | 2005 |
Disturbed homocysteine and methionine cycle intermediates S-adenosylhomocysteine and S-adenosylmethionine are related to degree of renal insufficiency in type 2 diabetes.
Topics: Aged; Cystathionine; Cysteine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Folic Acid; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Male; Methionine; Methylmalonic Acid; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcobalamins; Vitamin B 12; Vitamin B 6 | 2005 |
Plasma vitamin B12, folate and homocysteine levels in gastrectomized men.
Topics: Case-Control Studies; Folic Acid; Gastrectomy; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Male; Middle Aged; Peptic Ulcer; Risk Factors; Stomach Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Creatine metabolism in combined methylmalonic aciduria and homocystinuria.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Creatine; Female; Glycine; Homocysteine; Homocystinuria; Humans; Male; Methionine; Methylmalonic Acid; Vitamin B 12 | 2005 |
Spastic paraparesis as a manifestation of metabolic vitamin B12 deficiency: a case report.
Topics: Adult; Diet, Vegetarian; Evoked Potentials, Motor; Homocysteine; Humans; Male; Paraparesis, Spastic; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Methimazole-induced hypothyroidism paradoxically decreases homocysteine.
Topics: Adolescent; Adult; Female; Fibrinogen; Folic Acid; Homocysteine; Humans; Hypothyroidism; Lipids; Logistic Models; Male; Methimazole; Methionine; Plasminogen Activator Inhibitor 1; Thyrotropin; Vitamin B 12; Vitamin B 6 | 2005 |
Hyperhomocysteinemia in L-dopa treated Parkinson's disease patients: effect of cobalamin and folate administration.
Topics: Aged; Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Parkinson Disease; Vitamin B 12 | 2005 |
Nutritional and life style determinants of plasma homocysteine in schizophrenia patients.
Topics: Adolescent; Adult; Blood Chemical Analysis; Female; Folic Acid; Homocysteine; Humans; Life Style; Male; Middle Aged; Nutritional Status; Schizophrenia; Vitamin B 12 | 2005 |
Plasma homocysteine concentration and its relation to symptoms of vascular disease in psychogeriatric patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Creatinine; Cystatin C; Cystatins; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Protein S; Vascular Diseases; Vitamin B 12 | 2005 |
Homocysteine and related genetic polymorphisms in Down's syndrome IQ.
Topics: Alleles; Alzheimer Disease; Apolipoproteins E; Diagnostic and Statistical Manual of Mental Disorders; Down Syndrome; Folic Acid; Homocysteine; Humans; Intelligence; Karyotyping; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Transcobalamins; Vitamin B 12 | 2005 |
Associations between MTHFR 1793G>A and plasma total homocysteine, folate, and vitamin B in kidney transplant recipients.
Topics: Adult; Aged; Alleles; Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Kidney Diseases; Kidney Transplantation; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Treatment Outcome; Vitamin B 12 | 2005 |
[A clinical study of hyperhomocysteinemia in rheumatological diseases].
Topics: Adolescent; Adult; Child; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Rheumatic Diseases; Vitamin B 12 | 2005 |
Homocysteine, renal disease and cardiovascular disease in a remote Australian Aboriginal community.
Topics: Adult; Albuminuria; Arteriosclerosis; Australia; Cardiovascular Diseases; Cross-Sectional Studies; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Kidney Diseases; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Native Hawaiian or Other Pacific Islander; Polymorphism, Genetic; Regression Analysis; Rural Population; Vitamin B 12 | 2005 |
[Homocysteine and low dietary intake: two complementary forms of impairment (correction of improvement)].
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Thromboembolism; Vitamin B 12; Vitamin B 6 | 2005 |
Executive dysfunction in hyperhomocystinemia responds to homocysteine-lowering treatment.
Topics: Adult; Anticoagulants; Betaine; Cognition Disorders; Confusion; Disease Progression; Drug Therapy, Combination; Folic Acid; Frontal Lobe; Homocysteine; Humans; Hyperhomocysteinemia; Leukoaraiosis; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Remission Induction; Seizures; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2005 |
Relationship of homocysteine, folic acid and vitamin B12 with depression in a middle-aged community sample.
Topics: Aged; Antioxidants; Australia; Brain; Case-Control Studies; Causality; Creatinine; Cross-Sectional Studies; Depressive Disorder; Depressive Disorder, Major; Female; Folic Acid; Folic Acid Deficiency; Health Status Indicators; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Personality Assessment; Predictive Value of Tests; Psychometrics; Reference Values; Statistics as Topic; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Polymorphisms of genes involved in homocysteine metabolism in preeclampsia and in uncomplicated pregnancies.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Case-Control Studies; Cystathionine beta-Synthase; Female; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Vitamin B 12 | 2005 |
Effects of marathon running on plasma total homocysteine concentrations.
Topics: Adult; Blood Glucose; Body Composition; Fasting; Fatty Acids, Nonesterified; Folic Acid; Homocysteine; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Myocardial Infarction; Risk Factors; Running; Vitamin B 12; Waist-Hip Ratio | 2005 |
Reduced plasma homocysteine levels in levodopa/entacapone treated Parkinson patients.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cross-Sectional Studies; Drug Therapy, Combination; Enzyme Inhibitors; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Vitamin B 12 | 2005 |
Total homocysteine and its predictors in Dutch children.
Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Creatinine; Female; Folic Acid; Genotype; Homocysteine; Humans; Infant; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Netherlands; Predictive Value of Tests; Vitamin B 12 | 2005 |
Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people.
Topics: Aged; Aged, 80 and over; Body Weight; Bone and Bones; Cohort Studies; Creatine; Female; Fractures, Bone; Homocysteine; Humans; Immunoassay; Immunoradiometric Assay; Male; Middle Aged; Osteocalcin; Osteoporosis; Proportional Hazards Models; Regression Analysis; Risk; Risk Factors; Time Factors; Ultrasonography; Vitamin B 12 | 2005 |
[The plasma homocysteine, folic acid and vitamin B12 levels in young people with high risk for cardiovascular disease and its relation to metylentetrahydrofolate reductase (MTHFR) gene polymorphism].
Topics: Adult; Cardiovascular Diseases; Cytosine; Female; Folic Acid; Heterozygote; Homocysteine; Humans; Immunoassay; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Risk Factors; Thymine; Vitamin B 12 | 2005 |
Endothelial nitric oxide synthase -786T>C, but not 894G>T and 4a4b, polymorphism influences plasma homocysteine concentrations in persons with normal vitamin status.
Topics: Adult; Aged; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6; Vitamins | 2005 |
Methylenetetrahydrofolate reductase (MTHFR) polymorphism (C677T) in relation to homocysteine concentration in overweight and obese Thais.
Topics: Adolescent; Adult; Body Weight; Case-Control Studies; Female; Fluorescence Polarization Immunoassay; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Obesity; Polymorphism, Genetic; Thailand; Vitamin B 12 | 2005 |
[The relationship between carotid artery atherosclerosis and hyperhomocysteinaemia].
Topics: Adult; Aged; Aged, 80 and over; Carotid Artery Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2005 |
Maternal total homocysteine concentration and neonatal size in India.
Topics: Adult; Birth Weight; Erythrocytes; Female; Folic Acid; Gestational Age; Homocysteine; Humans; India; Infant, Newborn; Infant, Small for Gestational Age; Male; Maternal Nutritional Physiological Phenomena; Population Surveillance; Pregnancy; Pregnancy Complications; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Folate, vitamin B12, and risk of ischemic and hemorrhagic stroke: a prospective, nested case-referent study of plasma concentrations and dietary intake.
Topics: Adult; Aged; Brain Ischemia; Case-Control Studies; Cohort Studies; Diet; Female; Folic Acid; Hemorrhage; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Nutritional Status; Odds Ratio; Polymorphism, Genetic; Prospective Studies; Registries; Risk; Stroke; Sweden; Vitamin B 12 | 2005 |
Homocysteine, vitamin B 12 and folate in Alzheimer's and vascular dementias: the paradoxical effect of the superimposed type II diabetes mellitus condition.
Topics: Aged; Alzheimer Disease; Analysis of Variance; Dementia, Vascular; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12 | 2005 |
Gene--nutrition interactions in coronary artery disease: correlation between the MTHFR C677T polymorphism and folate and homocysteine status in a Korean population.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Coronary Artery Disease; Female; Folic Acid; Genotype; Homocysteine; Humans; Korea; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Nutritional Status; Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Vitamin B 12 | 2006 |
Blood homocysteine, folate and vitamin B-12 concentrations in patients with epilepsy receiving lamotrigine or sodium valproate for initial monotherapy.
Topics: Adult; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Lamotrigine; Male; Middle Aged; Triazines; Valproic Acid; Vitamin B 12 | 2005 |
Folate and cobalamin deficiencies and hyperhomocysteinemia in Bangladesh.
Topics: Adult; Aged; Areca; Bangladesh; Cohort Studies; Creatinine; Diagnosis, Differential; Diet, Vegetarian; Female; Folic Acid; Folic Acid Deficiency; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Prospective Studies; Sex Factors; Smoking; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Transcobalamin 776C->G polymorphism negatively affects vitamin B-12 metabolism.
Topics: Adult; Diet; Dietary Supplements; Female; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Genetic; Transcobalamins; Vitamin B 12 | 2005 |
[Folic acid in hyperhomocysteinemia?].
Topics: Contraindications; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Long-Term Care; Risk Factors; Spinal Diseases; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Prevalence of hyperhomocysteinaemia, activated protein C resistance and prothrombin gene mutation in inflammatory bowel disease.
Topics: Activated Protein C Resistance; Adult; Colitis, Ulcerative; Crohn Disease; Factor V; Factor VIII; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Middle Aged; Mutation; Protein C; Prothrombin; Vitamin B 12 | 2005 |
Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans.
Topics: Aged; Bone Density; Female; Folic Acid; Hip; Homocysteine; Humans; Male; Methylmalonic Acid; Osteoporosis; Radiography; United States; Vitamin B 12 | 2005 |
Prevalence of hyperhomocysteinemia in adult gluten-sensitive enteropathy at diagnosis: role of B12, folate, and genetics.
Topics: Adult; Biomarkers; Celiac Disease; Chromatography, High Pressure Liquid; DNA; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Prevalence; Prospective Studies; Radioimmunoassay; Risk Factors; Vitamin B 12 | 2005 |
Effect of homocysteine, folates, and cobalamin on endothelial cell- and copper-induced LDL oxidation.
Topics: Cells, Cultured; Copper; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Kinetics; Lipoproteins, LDL; Reference Values; Umbilical Veins; Vitamin B 12 | 2005 |
Increased LDL+VLDL oxidizability and plasma homocysteine levels in chronic alcoholic patients.
Topics: Adult; Alcoholism; Apolipoproteins B; Aryldialkylphosphatase; Cholesterol, HDL; Female; Folic Acid; Homocysteine; Humans; Lipid Peroxidation; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Vitamin B 12 | 2005 |
Cobalamin-responsive disorders and unreliability of cobalamin, methylmalonic acid, and homocysteine testing.
Topics: Diagnostic Errors; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
A homocysteine metabolism-related dietary pattern and the risk of coronary heart disease in two independent German study populations.
Topics: Aged; Body Mass Index; Case-Control Studies; Coronary Disease; Diet; Female; Folic Acid; Germany; Homocysteine; Humans; Middle Aged; Multivariate Analysis; Risk Factors; Vitamin B 12 | 2005 |
A B12-responsive internal ribosome entry site (IRES) element in human methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5' Untranslated Regions; Alternative Splicing; Animals; Binding Sites; Cell Line; Cells, Cultured; Codon; Codon, Initiator; COS Cells; Cross-Linking Reagents; Gene Deletion; Genes, Reporter; Homocysteine; Humans; Luciferases; Mice; Models, Genetic; NIH 3T3 Cells; Nucleic Acid Conformation; Plasmids; Protein Binding; Protein Biosynthesis; Protein Structure, Secondary; Ribosomes; Risk Factors; RNA; Transfection; Vitamin B 12 | 2005 |
Homocysteinemia as well as methylenetetrahydrofolate reductase polymorphism are associated with affective psychoses.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Age Factors; Aged; Aged, 80 and over; Case-Control Studies; Chi-Square Distribution; Dementia; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Schizophrenia; Vitamin B 12 | 2005 |
Insulin resistance is not related to plasma homocysteine concentration in healthy premenapausal women.
Topics: Adolescent; Adult; Age Factors; Blood Glucose; Body Mass Index; Cholesterol, HDL; Female; Folic Acid; Homocysteine; Humans; Insulin; Insulin Resistance; Premenopause; Triglycerides; Uric Acid; Vitamin B 12 | 2006 |
Biochemical indicators of B vitamin status in the US population after folic acid fortification: results from the National Health and Nutrition Examination Survey 1999-2000.
Topics: Adult; Aged; Dietary Supplements; Erythrocytes; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Nutrition Surveys; Reference Values; Time Factors; United States; Vitamin B 12 | 2005 |
The relation between homocysteine levels and development of Alzheimer's disease in mild cognitive impairment patients.
Topics: Aged; Alzheimer Disease; Cognition Disorders; Creatinine; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Sex Characteristics; Thyrotropin; Vitamin B 12; Vitamins | 2005 |
Homocysteine and cognitive performance in the Framingham offspring study: age is important.
Topics: Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Pyridoxine; Regression Analysis; Risk Factors; Vitamin B 12 | 2005 |
Homocysteine and serum markers of immune activation in primary dystonia.
Topics: Adult; Aged; Anti-Dyskinesia Agents; Biomarkers; Botulinum Toxins; C-Reactive Protein; Chromatography, High Pressure Liquid; Dystonic Disorders; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Immunity; Male; Middle Aged; Vitamin B 12 | 2005 |
Low levels of vitamin B12 and venous thromboembolic disease in elderly men.
Topics: Age Factors; Aged; Biomarkers; Case-Control Studies; Creatinine; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Risk Assessment; Thromboembolism; Venous Thrombosis; Vitamin B 12; Vitamin B Deficiency | 2005 |
Vitamin therapy may reduce hip fracture risk. Folate, B12 appear to reduce homocysteine levels.
Topics: Aged; Female; Folic Acid; Hip Fractures; Homocysteine; Humans; Male; Stroke; Vitamin B 12 | 2005 |
Association of red blood cell 5-methyltetrahydrofolate folate with bone mineral density in postmenopausal Iranian women.
Topics: Absorptiometry, Photon; Biomarkers; Body Mass Index; Bone Density; Erythrocytes; Female; Femur Neck; Homocysteine; Humans; Lumbar Vertebrae; Middle Aged; Osteoporosis, Postmenopausal; Population Surveillance; Tetrahydrofolates; Vitamin B 12 | 2005 |
High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study.
Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Diet; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2005 |
Plasma homocysteine, vitamin B12 and folate levels in age-related macular degeneration.
Topics: Aged; Aged, 80 and over; Choroidal Neovascularization; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Exudates and Transudates; Female; Folic Acid; Homocysteine; Humans; Luminescent Measurements; Macular Degeneration; Male; Middle Aged; Prospective Studies; Vitamin B 12 | 2006 |
Plasma homocysteine levels in patients with isolated coronary artery ectasia.
Topics: Biomarkers; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Dilatation, Pathologic; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Vitamin B 12 | 2005 |
Association of B vitamins status and homocysteine levels in elderly Taiwanese.
Topics: Age Factors; Aged; Aged, 80 and over; Cardiovascular Diseases; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nutrition Surveys; Nutritional Status; Sex Factors; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Complex | 2005 |
[Homocysteinemia].
Topics: Aged; Diagnosis, Differential; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Prognosis; Risk Assessment; Risk Factors; Time Factors; Vitamin B 12 | 2005 |
[Nutrition as heart issue: micronutrients protect women's hearts].
Topics: Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Micronutrients; Nutritional Requirements; Risk Factors; Sex Factors; Vitamin B 12 | 2005 |
Heavy alcohol intake, homocysteine and Type 2 diabetes.
Topics: Alcohol Drinking; Arteriosclerosis; Blood Glucose; Creatinine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Folic Acid; gamma-Glutamyltransferase; Homocysteine; Humans; Male; Middle Aged; Prevalence; Risk Factors; Vitamin B 12 | 2005 |
Long-term consumption of a raw food diet is associated with favorable serum LDL cholesterol and triglycerides but also with elevated plasma homocysteine and low serum HDL cholesterol in humans.
Topics: Adult; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Diet, Vegetarian; Female; Folic Acid; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Triglycerides; Vegetables; Vitamin B 12 | 2005 |
[Effect of the supplementation of vitamins B12, B6 and folic acid on homocysteine and plasmatic lipids in patients with hyperlipoproteinemic secondary type IV].
Topics: Adult; Aged; Biomarkers; Cholesterol, HDL; Coronary Disease; Folic Acid; Homocysteine; Humans; Hyperlipoproteinemia Type IV; Lipids; Lipoproteins, LDL; Male; Middle Aged; Risk Factors; Triglycerides; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2005 |
Folate and vitamin B12 in relation to lactation: a 9-month postpartum follow-up study.
Topics: Adult; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lactation; Life Style; Methylmalonic Acid; Nutritional Requirements; Nutritional Status; Postpartum Period; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Food-cobalamin malabsorption in elderly patients: clinical manifestations and treatment.
Topics: Aged; Aged, 80 and over; Asthenia; Cognition Disorders; Cohort Studies; Confusion; Edema; Erythrocyte Indices; Female; Follow-Up Studies; Gastritis, Atrophic; Hematologic Diseases; Hemoglobins; Homocysteine; Humans; Jaundice; Malabsorption Syndromes; Male; Paresthesia; Polyneuropathies; Reflex, Abnormal; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
A laboratory algorithm with homocysteine as the primary parameter reduces the cost of investigation of folate and cobalamin deficiency.
Topics: Algorithms; Folic Acid Deficiency; Homocysteine; Humans; Research; Research Design; Sweden; Vitamin B 12 | 2005 |
Homocysteine and B vitamins in mild cognitive impairment and dementia.
Topics: Aged; Cognition Disorders; Dementia; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12 | 2005 |
Do low doses of folic acid result in maximum lowering of homocysteine?
Topics: Dietary Supplements; Dose-Response Relationship, Drug; Drug Synergism; Evidence-Based Medicine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Vitamin B 12; Vitamin B 6 | 2005 |
Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery.
Topics: Betaine; Choline; Chromatography, Liquid; Creatinine; Cross-Sectional Studies; Female; Fetal Blood; Folic Acid; Health Status Indicators; Homocysteine; Humans; Infant, Newborn; Methylation; Oxidation-Reduction; Pregnancy; Regression Analysis; Sarcosine; Vitamin B 12 | 2005 |
Homocysteine, vitamin B-12, and folic acid and the risk of cognitive decline in old age: the Leiden 85-Plus study.
Topics: Aged; Aged, 80 and over; Aging; Cognition; Cross-Sectional Studies; Dementia; Female; Folic Acid; Homocysteine; Humans; Linear Models; Longitudinal Studies; Male; Neuropsychological Tests; Prospective Studies; Risk Factors; Vitamin B 12 | 2005 |
In pregnant women who smoke, caffeine consumption is associated with an increased level of homocysteine.
Topics: Caffeine; Central Nervous System Stimulants; Coffee; Female; Homocysteine; Humans; Pregnancy; Prospective Studies; Smoking; Tea; Vitamin B 12 | 2005 |
Folate, vitamin B12, and homocysteine levels in South Asian women with growth-retarded fetuses.
Topics: Adult; Age Factors; Birth Weight; Cohort Studies; Female; Fetal Blood; Fetal Development; Fetal Growth Retardation; Fluorescence Polarization Immunoassay; Folic Acid; Homocysteine; Humans; Luminescent Measurements; Pakistan; Pregnancy; Pregnancy Outcome; Prospective Studies; Social Class; Ultrasonography, Prenatal; Vitamin B 12 | 2005 |
The effect of MTHFR(C677T) genotype on plasma homocysteine concentrations in healthy children is influenced by gender.
Topics: Analysis of Variance; Child; Cross-Sectional Studies; Diet; Female; Folic Acid; Genotype; Greece; Homocysteine; Humans; Male; Mental Recall; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Sex Factors; Vitamin B 12 | 2006 |
Vitamin Intervention For Stroke Prevention trial: an efficacy analysis.
Topics: Aged; Disease-Free Survival; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Ischemia; Male; Middle Aged; Models, Statistical; Randomized Controlled Trials as Topic; Stroke; Time Factors; Treatment Outcome; Vitamin B 12; Vitamins | 2005 |
[Untreated homocystinuria in adulthood].
Topics: Adult; Age Factors; Angina Pectoris; Betaine; Diagnosis, Differential; Drug Therapy, Combination; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Intervertebral Disc Displacement; Lens Subluxation; Male; Marfan Syndrome; Myopia; Osteoporosis; Retinal Detachment; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2005 |
Plasma total homocysteine and memory in the elderly: the Hordaland Homocysteine Study.
Topics: Aged; Biomarkers; Cross-Sectional Studies; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Memory; Memory Disorders; Prospective Studies; Risk Factors; Vitamin B 12 | 2005 |
The influence of genetic and environmental factors on plasma homocysteine concentrations in a population at high risk for coronary artery disease.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Coronary Artery Disease; Cystathionine beta-Synthase; Environment; Erythrocytes; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Polymorphism, Genetic; Risk Factors; Vitamin B 12; Vitamin B 6 | 2005 |
Hyperhomocysteinemia and methylenetetrahydrofolate reductase 677C-->T and 1298A-->C mutations in patients with inflammatory bowel disease.
Topics: Adult; Confidence Intervals; Data Interpretation, Statistical; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Odds Ratio; Prevalence; Sex Factors; Thromboembolism; Vitamin B 12 | 2005 |
Changes in plasma homocysteine levels of rats with experimentally induced hypothyroidism and hyperthyroidism.
Topics: Animals; Antithyroid Agents; Cholesterol; Folic Acid; Homocysteine; Hyperthyroidism; Hypothyroidism; Lipids; Male; Propylthiouracil; Rats; Rats, Wistar; Thyroid Function Tests; Thyroxine; Vitamin B 12 | 2005 |
Hyperhomocysteinemia is associated with volumetric white matter change in patients with small vessel disease.
Topics: Aged; Brain; Cerebrovascular Disorders; Cognition Disorders; Cohort Studies; Creatinine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Psychiatric Status Rating Scales; Psychometrics; Regression Analysis; Risk Factors; Stroke; Vitamin B 12 | 2006 |
Association of MTRRA66G polymorphism (but not of MTHFR C677T and A1298C, MTRA2756G, TCN C776G) with homocysteine and coronary artery disease in the French population.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Alleles; Case-Control Studies; Coronary Artery Disease; Female; Ferredoxin-NADP Reductase; Folic Acid; France; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Transcobalamins; Vitamin B 12; White People | 2005 |
Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Brain; Causality; Cerebral Amyloid Angiopathy; Cognition Disorders; Creatinine; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Memory Disorders; Middle Aged; Neurodegenerative Diseases; Parkinson Disease; Predictive Value of Tests; Vitamin B 12 | 2005 |
Design and statistical issues in the homocysteinemia in kidney and end stage renal disease (HOST) study.
Topics: Adult; Cause of Death; Double-Blind Method; Folic Acid; Homocysteine; Hospitals, Veterans; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Middle Aged; Multicenter Studies as Topic; Patient Selection; Prospective Studies; Pyridoxine; Randomized Controlled Trials as Topic; Renal Dialysis; Research Design; Treatment Outcome; Vitamin B 12 | 2004 |
B vitamins and homocysteine.
Topics: Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Vitamin B 12; Vitamin B 6 | 2005 |
Altered vitamin B12 status in recreational endurance athletes.
Topics: Adult; Biomarkers; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Nutritional Status; Physical Endurance; Vitamin B 12; Vitamin B Complex | 2005 |
Brain MRI white matter hyperintensities and one-carbon cycle metabolism in non-geriatric outpatients with major depressive disorder (Part II).
Topics: Adolescent; Adult; Aged; Ambulatory Care; Brain; Demography; Depressive Disorder, Major; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Vitamin B 12 | 2005 |
High levels of homocysteine and low serum paraoxonase 1 arylesterase activity in children with autism.
Topics: Aryldialkylphosphatase; Autistic Disorder; Carboxylic Ester Hydrolases; Child; Erythrocytes; Female; Glutathione Peroxidase; Homocysteine; Humans; Male; Vitamin B 12 | 2006 |
Brain MRI white matter hyperintensities and one-carbon cycle metabolism in non-geriatric outpatients with major depressive disorder (Part I).
Topics: Adolescent; Adult; Aged; Brain; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Severity of Illness Index; Vitamin B 12 | 2005 |
Homocysteine and cognition--no longer a hypothesis?
Topics: Aged; Alzheimer Disease; Cognition; Cognition Disorders; Homocysteine; Humans; Methionine; Models, Biological; Models, Theoretical; Neurodegenerative Diseases; Vitamin B 12; Vitamins | 2006 |
Retinal vein occlusion, homocysteine, and methylene tetrahydrofolate reductase genotype.
Topics: Aged; Case-Control Studies; DNA Mutational Analysis; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Genetic; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2005 |
Plasma homocysteine and lipoprotein (a) levels in Turkish patients with metabolic syndrome.
Topics: Adult; Coronary Disease; Female; Folic Acid; Homocysteine; Humans; Insulin Resistance; Lipoprotein(a); Male; Metabolic Syndrome; Middle Aged; Reference Values; Risk Factors; Statistics as Topic; Turkey; Vitamin B 12 | 2005 |
Anger attacks in major depressive disorder and serum levels of homocysteine.
Topics: Adult; Age Factors; Aged; Alcohol Drinking; Anger; Creatinine; Depressive Disorder, Major; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Severity of Illness Index; Smoking; Surveys and Questionnaires; Time Factors; Vitamin B 12 | 2006 |
Folate, homocysteine, and arsenic metabolism in arsenic-exposed individuals in Bangladesh.
Topics: Adult; Arsenic; Arsenicals; Bangladesh; Cacodylic Acid; Creatine; Creatinine; Cross-Sectional Studies; Environmental Exposure; Environmental Monitoring; Female; Folic Acid; Fresh Water; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12; Water Pollutants, Chemical | 2005 |
Elevated plasma homocysteine in obese schoolchildren with early atherosclerosis.
Topics: Atherosclerosis; Body Mass Index; Brachial Artery; Carotid Artery, Internal; Case-Control Studies; Child; Dyslipidemias; Female; Folic Acid; Homocysteine; Humans; Hypertension; Male; Obesity; Regional Blood Flow; Tunica Intima; Tunica Media; Ultrasonography; Vitamin B 12 | 2006 |
Elevated homocysteine levels in patients with end-stage renal disease.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Risk Factors; Statistics, Nonparametric; Vitamin B 12 | 2005 |
Polymorphisms of methylenetetrahydrofolate reductase and the risk of prostate cancer: a nested case-control study.
Topics: Adult; Case-Control Studies; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Genetic; Prospective Studies; Prostatic Neoplasms; Risk; Sweden; Vitamin B 12 | 2006 |
Plasma reduced homocysteine and other aminothiol concentrations in patients with CKD.
Topics: Adult; Aged; Atherosclerosis; Biomarkers; C-Reactive Protein; Chronic Disease; Cysteine; Dipeptides; Female; Folic Acid; Glutathione; Hemodiafiltration; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Diseases; Kidney Failure, Chronic; Male; Middle Aged; Oxidation-Reduction; Peritoneal Dialysis; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis; Vitamin B 12 | 2006 |
Plasma hyperhomocysteinemia, MTHFR polymorphism and thromboembolic disease: an example of gene-nutrition interactions in chronic disease.
Topics: Chronic Disease; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Thromboembolism; Vitamin B 12; Vitamin B 6 | 2005 |
Influence of methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, B vitamins and other factors on plasma homocysteine and risk of thromboembolic disease in Chinese.
Topics: Adult; Aged; Aged, 80 and over; Coronary Disease; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Polymorphism, Genetic; Risk Factors; Thromboembolism; Vitamin B 12; Vitamin B 6 | 2005 |
Factors involved in baseline hyperhomocysteinemia in renal transplantation.
Topics: Adult; Aged; C-Reactive Protein; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Prospective Studies; Reference Values; Vitamin B 12 | 2005 |
Homocysteine in assisted reproduction: does oestradiol influence homocysteine levels?
Topics: Adult; Estradiol; Female; Folic Acid; Homocysteine; Humans; Infertility, Female; Reproductive Techniques, Assisted; Vitamin B 12 | 2006 |
Plasma homocysteine and vascular disease in psychogeriatric patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Confusion; Dementia; Dementia, Vascular; Depressive Disorder; Female; Folic Acid; Homocysteine; Humans; Kidney Function Tests; Male; Middle Aged; Natriuretic Peptide, Brain; Neuropsychological Tests; Peptide Fragments; Reference Values; Risk Factors; Vitamin B 12 | 2006 |
Moderate hyperhomocysteinemia and early-onset central retinal vein occlusion.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Pyridoxal Phosphate; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2006 |
Increased plasma protein homocysteinylation in hemodialysis patients.
Topics: Adult; Aged; Blood Proteins; Cardiovascular Diseases; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; In Vitro Techniques; Male; Middle Aged; Models, Molecular; Protein Binding; Protein Processing, Post-Translational; Renal Dialysis; Serum Albumin; Uremia; Vitamin B 12; Vitamin B 6; Xenobiotics | 2006 |
Homocysteine: call off the funeral.
Topics: Coronary Artery Disease; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Stroke; Vitamin B 12 | 2006 |
A daily intake of approximately 6 microg vitamin B-12 appears to saturate all the vitamin B-12-related variables in Danish postmenopausal women.
Topics: Administration, Oral; Adult; Aged; Denmark; Diet; Diet Records; Dietary Supplements; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Nutritional Status; Postmenopause; Statistics, Nonparametric; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2006 |
Plasma total homocysteine level and bone mineral density: the Hordaland Homocysteine Study.
Topics: Age Distribution; Aged; Bone Density; Cohort Studies; Confidence Intervals; Female; Folic Acid; Hematologic Tests; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Odds Ratio; Polymorphism, Genetic; Regression Analysis; Sex Distribution; Vitamin B 12 | 2006 |
Effects of common anti-epileptic drug monotherapy on serum levels of homocysteine, vitamin B12, folic acid and vitamin B6.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Phenytoin; Pyridoxal Phosphate; Reference Values; Valproic Acid; Vitamin B 12 | 2006 |
Dietary and genetic determinants of homocysteine levels among Mexican women of reproductive age.
Topics: Adolescent; Adult; Alleles; Chromatography, High Pressure Liquid; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mexico; Polymerase Chain Reaction; Polymorphism, Genetic; Radioimmunoassay; Surveys and Questionnaires; Vitamin B 12 | 2006 |
Relationship between plasma S-adenosylhomocysteine concentration and glomerular filtration rate in children.
Topics: Adolescent; Child; Child, Preschool; Congenital Hypothyroidism; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Infant; Kidney Diseases; S-Adenosylhomocysteine; Vitamin B 12 | 2006 |
[Hyperhomocysteinemia as a vascular risk factor in chronic hemodialysis patients].
Topics: Atherosclerosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methylenetetrahydrofolate Reductase (NADPH2); Renal Dialysis; Risk Factors; Thrombosis; Vitamin B 12; Vitamin B Complex | 2005 |
The maternal combined supplementation of folic acid and Vitamin B(12) suppresses ethanol-induced developmental toxicity in mouse fetuses.
Topics: Abnormalities, Drug-Induced; Alcoholic Intoxication; Animals; Bone and Bones; Dietary Supplements; Embryo Implantation; Embryo Loss; Ethanol; Female; Fetal Development; Fetal Growth Retardation; Folic Acid; Gestational Age; Homocysteine; Mice; Pregnancy; Vitamin B 12 | 2006 |
Homocysteine and its determinants in nondialyzed chronic kidney disease patients.
Topics: Anthropometry; Case-Control Studies; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Function Tests; Linear Models; Male; Middle Aged; Nutrition Assessment; Nutritional Status; Prevalence; Vitamin B 12 | 2006 |
Three Bs for the brain.
Topics: Aged; Dementia; Folic Acid; Homocysteine; Humans; Male; Thinking; Vitamin B 12; Vitamin B 6 | 2005 |
Cellular folate vitamer distribution during and after correction of vitamin B12 deficiency: a case for the methylfolate trap.
Topics: Chromatography, Liquid; DNA Methylation; Erythrocytes; Folic Acid; Homocysteine; Homozygote; Humans; Hydroxocobalamin; Male; Mass Spectrometry; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Pretreatment plasma folate modulates the pharmacodynamic effect of high-dose methotrexate in children with acute lymphoblastic leukemia and non-Hodgkin lymphoma: "folate overrescue" concept revisited.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Infant; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vitamin B 12; Vitamin B Complex | 2006 |
Dietary and other lifestyle correlates of serum folate concentrations in a healthy adult population in Crete, Greece: a cross-sectional study.
Topics: Adult; Aged; Analysis of Variance; Coffee; Cross-Sectional Studies; Diet; Diet Records; Fabaceae; Female; Folic Acid; Fruit; Greece; Homocysteine; Humans; Life Style; Male; Middle Aged; Nutrition Policy; Smoking; Solanum tuberosum; Surveys and Questionnaires; Vegetables; Vitamin B 12 | 2006 |
Total plasma homocysteine, folate, and vitamin B12 status in healthy Iranian adults: the Tehran homocysteine survey (2003-2004)/a cross-sectional population based study.
Topics: Adult; Age Factors; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Iran; Male; Middle Aged; Nutrition Surveys; Prevalence; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Diagnostic significance of urinary thiodiglycolic acid as a possible tool for studying the role of vitamins B12 and folates in the metabolism of thiolic substances.
Topics: Adult; Betaine; Biomarkers; Folic Acid; Homocysteine; Humans; Injections, Intramuscular; Leucovorin; Male; Sulfhydryl Compounds; Thioglycolates; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Serum homocysteine, vitamin B 12 and folic acid levels in different types of glaucoma.
Topics: Aged; Analysis of Variance; Case-Control Studies; Exfoliation Syndrome; Female; Folic Acid; Glaucoma; Glaucoma, Open-Angle; Homocysteine; Humans; Male; Middle Aged; Osmolar Concentration; Vitamin B 12 | 2006 |
Hyperhomocysteinemia in chronic renal failure patients: relation to tissue factor and platelet aggregation.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Platelet Aggregation; Renal Dialysis; Thromboplastin; Vitamin B 12; Vitamin B 6 | 2006 |
Prevalence of methylenetetrahydrofolate reductase 677T and 1298C alleles and folate status: a comparative study in Mexican, West African, and European populations.
Topics: Adolescent; Adult; Africa, Western; Alleles; Europe; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mexico; Middle Aged; Polymorphism, Genetic; Regression Analysis; Vitamin B 12 | 2006 |
Homocysteine trials--clear outcomes for complex reasons.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Myocardial Infarction; Secondary Prevention; Vascular Diseases; Vitamin B 12; Vitamin B 6 | 2006 |
[Relations between serum homocysteine and folic acid levels with congenital heart disease].
Topics: Adolescent; Adult; Case-Control Studies; Child; Child, Preschool; Female; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Infant; Male; Parents; Vitamin B 12; Young Adult | 2005 |
Impact of renal function or folate status on altered plasma homocysteine levels in hypothyroidism.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Creatinine; Cystatins; Data Interpretation, Statistical; Female; Folic Acid; Homocysteine; Humans; Hypothyroidism; Kidney; Male; Middle Aged; Nephelometry and Turbidimetry; Vitamin B 12 | 2006 |
Cobalamin status during normal pregnancy and postpartum: a longitudinal study comprising 406 Danish women.
Topics: Adult; Cohort Studies; Denmark; Female; Follow-Up Studies; Hemoglobins; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Postpartum Period; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimester, Third; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Hyperhomocysteinemia in patients with arterial occlusive disease.
Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Risk Assessment; Risk Factors; Vitamin B 12 | 2006 |
Hyperhomocysteinemia and hypercoagulability in primary biliary cirrhosis.
Topics: Adult; Aged; Antithrombin III; Female; Folic Acid; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia; Liver Cirrhosis, Biliary; Male; Middle Aged; Peptide Hydrolases; Platelet Function Tests; Thrombomodulin; Thrombophilia; Thromboplastin; Vitamin B 12; Vitamin B 6 | 2006 |
Testing the homocysteine hypothesis in end-stage renal disease: Problems and a possible solution.
Topics: Clinical Trials as Topic; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Vitamin B 12 | 2006 |
Folate supplementation does not affect biochemical markers of bone turnover.
Topics: Biomarkers; Bone and Bones; Bone Remodeling; Collagen; Collagen Type I; Diet; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Osteocalcin; Peptide Fragments; Peptides; Procollagen; Vitamin B 12; Vitamin B Complex | 2006 |
Alcohol consumption and plasma homocysteine.
Topics: Alcohol Drinking; Cross-Sectional Studies; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Smoking; Surveys and Questionnaires; Vitamin B 12 | 2005 |
Vitamin B12 and vitamin B6 supplementation is needed among adults with phenylketonuria (PKU).
Topics: Adolescent; Adult; Diet, Protein-Restricted; Female; Folic Acid; Homocysteine; Humans; Male; Phenylketonurias; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2006 |
Factor V Leiden, pregnancy complications and adverse outcomes: the Hordaland Homocysteine Study.
Topics: Adult; Factor V; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Maternal Age; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Norway; Odds Ratio; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Retrospective Studies; Risk Factors; Smoking; Vitamin B 12 | 2006 |
Clinical significance of homocysteine in elderly hospitalized patients.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Creatinine; Female; Hemoglobins; Homocysteine; Humans; Lymphocyte Count; Male; Neutrophils; Nutritional Status; Predictive Value of Tests; Risk Factors; Serum Albumin; Statistics, Nonparametric; Survival Analysis; Triazoles; Vitamin B 12 | 2006 |
Folate supplementation and cardiovascular disease.
Topics: Cardiovascular Diseases; Folic Acid; Hematinics; Homocysteine; Humans; Randomized Controlled Trials as Topic; Stroke; Vitamin B 12; Vitamin B 6 | 2006 |
Effect of homocysteine lowering by 5-methyltetrahydrofolate on redox status in hyperhomocysteinemia.
Topics: Adult; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; DNA; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Sulfhydryl Compounds; Tetrahydrofolates; Vitamin B 12; Vitamin E | 2006 |
Mild hyperhomocysteinemia and the common C677T polymorphism of methylene tetrahydrofolate reductase gene are not associated with the metabolic syndrome in Type 2 diabetes.
Topics: Adult; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Insulin Resistance; Linear Models; Male; Metabolic Syndrome; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Obesity; Polymorphism, Genetic; Triglycerides; Vitamin B 12 | 2006 |
Total serum homocysteine, folate and vitamin B12 in a Greek school age population.
Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Age Factors; Aging; Blood Pressure; Cardiovascular Diseases; Child; Child Nutritional Physiological Phenomena; Female; Folic Acid; Greece; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Male; Reference Values; Risk Factors; Sex Factors; Social Class; Vitamin B 12; Vitamin B Complex | 2006 |
Effect of maternal exposure to homocystine on sodium valproate-induced neural tube defects in the mouse embryos.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Fetal Growth Retardation; Folic Acid; Gestational Age; Homocysteine; Homocystine; Mice; Neural Tube Defects; Pregnancy; Random Allocation; Teratogens; Valproic Acid; Vitamin B 12 | 2006 |
Folic acid, vitamin B12, MTHFR genotypes, and plasma homocysteine.
Topics: Aged; Aortic Aneurysm, Abdominal; Atherosclerosis; Carotid Artery Diseases; Folic Acid; Genotype; Homocysteine; Humans; Ischemia; Leg; Male; Methylenetetrahydrofolate Reductase (NADPH2); Peripheral Vascular Diseases; Risk Factors; Vitamin B 12 | 2006 |
Iron and the folate-vitamin B12-methylation pathway in multiple sclerosis.
Topics: Adult; Anti-Inflammatory Agents; Black People; Dietary Fats; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Interferons; Iron; Magnetic Resonance Imaging; Male; Methylation; Multiple Sclerosis; Nutritional Status; Patient Compliance; Pilot Projects; Prednisone; Vitamin B 12; White People | 2006 |
Plasma homocysteine levels and vitamin B status in patients with Pseudoexfoliation syndrome.
Topics: Aged; Exfoliation Syndrome; Eye; Female; Folic Acid; Glaucoma; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retinal Vein Occlusion; Risk Factors; Turkey; Vitamin B 12; Vitamin B 6 | 2006 |
Evidence for associations between common polymorphisms of estrogen receptor beta gene with homocysteine and nitric oxide.
Topics: Aged; Arginine; Body Mass Index; Cardiovascular Diseases; Cross-Sectional Studies; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Folic Acid; Genetic Variation; Genotype; Homocysteine; Humans; Linkage Disequilibrium; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Polymorphism, Single Nucleotide; Postmenopause; Risk Factors; Vitamin B 12 | 2006 |
The association between atopy and factors influencing folate metabolism: is low folate status causally related to the development of atopy?
Topics: Adult; Cross-Sectional Studies; Diet; Female; Folic Acid; Genotype; Homocysteine; Humans; Hypersensitivity; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Polymorphism, Genetic; Riboflavin; Risk Assessment; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6 | 2006 |
Elevated second trimester serum homocysteine levels in women with gestational diabetes mellitus.
Topics: Adult; Body Mass Index; Cross-Sectional Studies; Diabetes, Gestational; Female; Folic Acid; Gestational Age; Glucose Intolerance; Homocysteine; Humans; Pregnancy; Pregnancy Trimester, Second; Reference Values; Vitamin B 12 | 2006 |
[Lowering plasma homocysteine with vitamins B6, B12, and folic acid. Effect on lipids concentration in patients with secondary hyperlipoproteinemia type IV, with and without Lovastatina treatment].
Topics: Aged; Anticholesteremic Agents; Folic Acid; Homocysteine; Humans; Hyperlipoproteinemia Type IV; Lipids; Lovastatin; Middle Aged; Time Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2006 |
[Homocysteine level, relationship with cardiovascular risk factors in selected Polish population].
Topics: Adult; Aged; Coronary Artery Disease; Environmental Monitoring; Epidemiological Monitoring; Female; Folic Acid; Health Status; Homocysteine; Humans; Life Style; Male; Middle Aged; Poland; Risk Factors; Rural Population; Smoking; Urban Population; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2005 |
Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in patients with Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Single Nucleotide; Reference Values; Vitamin B 12 | 2006 |
Association of a 31 bp VNTR in the CBS gene with postload homocysteine concentrations in the Framingham Offspring Study.
Topics: Aged; Cohort Studies; Cystathionine beta-Synthase; Female; Folic Acid; Heterozygote; Homocysteine; Humans; Male; Methionine; Middle Aged; Minisatellite Repeats; Nuclear Family; Vitamin B 12; Vitamin B 6 | 2006 |
[Better prognosis for stroke patients].
Topics: Aged, 80 and over; Bias; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Humans; Myocardial Infarction; Randomized Controlled Trials as Topic; Stroke; Vitamin B 12; Vitamin B 6 | 2006 |
Polymorphism C776G in the transcobalamin II gene and homocysteine, folate and vitamin B12 concentrations. Association with MTHFR C677T and A1298C and MTRR A66G polymorphisms in healthy children.
Topics: Brazil; Child; Child, Preschool; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Multivariate Analysis; Polymorphism, Genetic; Reference Values; Risk Factors; Transcobalamins; Vitamin B 12 | 2007 |
Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetes.
Topics: Adult; Aged; Aged, 80 and over; Arizona; Cardiovascular Diseases; Cause of Death; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Folic Acid; Homocysteine; Humans; Indians, North American; Infections; Longitudinal Studies; Male; Middle Aged; Proportional Hazards Models; Serum Albumin; Vitamin B 12 | 2007 |
Homocysteine, folate and vitamin b12 in patients with coronary heart disease.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Chromatography, High Pressure Liquid; Coronary Disease; Creatinine; Diet; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Vitamin B 12; Vitamin B Complex | 2006 |
[Homocysteine lowering with folic acid and B vitamins in vascular disease].
Topics: Aged; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Treatment Outcome; Vascular Diseases; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2006 |
Body composition: an important determinant of homocysteine and methionine concentrations in healthy individuals.
Topics: Adipose Tissue; Adult; Body Composition; Body Water; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Menopause; Methionine; Middle Aged; Muscle, Skeletal; Risk Factors; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
G1793A polymorphisms in the methylene-tetrahydrofolate gene: effect of folic acid on homocysteine levels.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Folic Acid; Gene Frequency; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Vitamin B 12 | 2006 |
[The effect of lowering plasma homocysteine levels on some parameters of thrombotic activity in haemodialyzed patients with chronic renal failure].
Topics: Aged; Dose-Response Relationship, Drug; Female; Folic Acid; Hematologic Tests; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Reference Values; Renal Dialysis; Thrombosis; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2004 |
Nutritional determinants of plasma total homocysteine distribution in the Canary Islands.
Topics: Adolescent; Adult; Age Factors; Aged; Biomarkers; Cross-Sectional Studies; Diet; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Mental Recall; Middle Aged; Nutrition Surveys; Prevalence; Reference Values; Sex Factors; Spain; Surveys and Questionnaires; Vitamin B 12 | 2007 |
Early effect of sodium valproate and carbamazepine monotherapy on homocysteine metabolism in children with epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Prospective Studies; Pyridoxal Phosphate; Valproic Acid; Vitamin B 12 | 2006 |
Hyperhomocysteinaemia, thrombosis and pernicious anaemia.
Topics: Adult; Aged; Anemia, Pernicious; Female; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Middle Aged; Thrombosis; Vitamin B 12 | 2006 |
[Oral treatment of vitamin B12 deficiency in subacute combined degeneration].
Topics: Administration, Oral; Adult; Anemia, Pernicious; Autoantibodies; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Intrinsic Factor; Magnetic Resonance Imaging; Methylmalonic Acid; Neurologic Examination; Spinal Cord; Spinal Cord Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Plasma homocysteine and risk of coexisting silent brain infarction in Alzheimer's disease.
Topics: Aged; Alleles; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Cell Death; Cerebral Infarction; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Genotype; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Neurons; Peptide Fragments; Risk Factors; tau Proteins; Vitamin B 12 | 2005 |
[Factors influencing homocysteineamia in type 2 diabetic patients].
Topics: Diabetes Mellitus, Type 2; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Male; Metformin; Middle Aged; Obesity; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Plasma homocysteine, folate and vitamin B(12) compared between rural Gambian and UK adults.
Topics: Adult; Age Distribution; Black People; Female; Folic Acid; Gambia; Homocysteine; Humans; Lactation; Male; Middle Aged; Pregnancy; Rural Health; Sex Distribution; United Kingdom; Vitamin B 12; White People | 2006 |
Methylenetetrahydrofolate reductase gene polymorphism in Indian stroke patients.
Topics: Adolescent; Adult; Aged; Blotting, Northern; Chi-Square Distribution; Child; Child, Preschool; DNA Mutational Analysis; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Stroke; Vitamin B 12 | 2006 |
Homocysteine, folic acid and B12 serum levels in pregnancy complicated with preeclampsia.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Outcome; Prospective Studies; Risk Factors; Vitamin B 12 | 2007 |
Plasma homocysteine, cobalamin/folate status, and vascular disease in a large population of psychogeriatric patients.
Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Depressive Disorder; Female; Folic Acid; Hematocrit; Homocysteine; Humans; Male; Mental Disorders; Middle Aged; Nutritional Status; Population; Sweden; Vascular Diseases; Vitamin B 12 | 2006 |
Prospective evaluation of a peripherally administered three-in-one parenteral nutrition product in dogs.
Topics: Amino Acids; Animals; Catheterization, Peripheral; Dog Diseases; Dogs; Equipment Failure; Fat Emulsions, Intravenous; Female; Folic Acid; Food, Formulated; Homocysteine; Male; Parenteral Nutrition; Prospective Studies; Safety; Time Factors; Treatment Outcome; Vitamin B 12 | 2006 |
Behavioural and psychological symptoms of Alzheimer type dementia are not correlated with plasma homocysteine concentration.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Neuropsychological Tests; Psychological Tests; Severity of Illness Index; Vitamin B 12 | 2006 |
Folate, vitamin B12 and total homocysteine levels in neonates from Brazil.
Topics: Adult; Cross-Sectional Studies; Dietary Supplements; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Male; Nutritional Status; Pregnancy; Prenatal Care; Social Class; Socioeconomic Factors; Vitamin B 12; Vitamin B Complex | 2007 |
Homocysteine, vitamin B12 and folate levels in premature coronary artery disease.
Topics: Adult; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Risk Factors; Sex Characteristics; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Homocysteine lowering and cognitive performance.
Topics: Aged; Cognition; Cognition Disorders; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B Complex | 2006 |
Reference range of total serum homocysteine level and dietary indexes in healthy Greek schoolchildren aged 6-15 years.
Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Aging; Anthropometry; Blood Pressure; Body Mass Index; Child; Child Nutritional Physiological Phenomena; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Reference Values; Sex Characteristics; Vitamin B 12 | 2006 |
[Homocysteine as a cardiovascular marker and risk factor].
Topics: Cause of Death; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Myocardial Infarction; Risk Factors; Secondary Prevention; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2006 |
Effect of regular exercise on homocysteine concentrations: the HERITAGE Family Study.
Topics: Adolescent; Adult; Aged; Alleles; Bicycling; Black People; Body Height; Body Mass Index; Body Weight; Cotinine; Creatinine; Ethnicity; Exercise; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Middle Aged; Oxygen; Physical Fitness; Sex Characteristics; Vitamin B 12; Vitamins; Waist-Hip Ratio; White People | 2006 |
Hyperhomocysteinemia is associated with deep venous thrombosis of the lower extremities in Tunisian patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Leg; Male; Middle Aged; Prevalence; Recurrence; Tunisia; Venous Thrombosis; Vitamin B 12 | 2007 |
Circulating homocysteine levels in patients with type 2 diabetes mellitus.
Topics: Aged; Blood Glucose; Coronary Angiography; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Folic Acid; Genotype; Glomerular Filtration Rate; Glycated Hemoglobin; Homocysteine; Humans; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Polymorphism, Genetic; Up-Regulation; Vitamin B 12 | 2008 |
Tutorial in biostatistics: Analyzing associations between total plasma homocysteine and B vitamins using optimal categorization and segmented regression.
Topics: Algorithms; Canada; Data Interpretation, Statistical; Folic Acid; Homocysteine; Humans; Linear Models; Models, Statistical; Nutrition Surveys; Regression Analysis; Vitamin B 12; Vitamin B Complex | 2006 |
Association between the NAT1 1095C > A polymorphism and homocysteine concentration.
Topics: Adult; Alleles; Arylamine N-Acetyltransferase; Base Sequence; DNA Primers; Female; Folic Acid; Genotype; Homocysteine; Humans; Isoenzymes; Male; Polymorphism, Single Nucleotide; Smoking; Vitamin B 12 | 2006 |
Association of homocysteine, vitamin B12, folic acid, and MTHFR C677T in patients with a thrombotic event or recurrent fetal loss.
Topics: Abortion, Habitual; Adolescent; Adult; Aged; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors; Thrombosis; Vitamin B 12 | 2007 |
[Increase of homocysteine in cardiovascular diseases in Hungary].
Topics: Adult; Aged; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, HDL; COUP Transcription Factor II; Diabetes Mellitus, Type 2; Factor XIII; Female; Folic Acid; Homocysteine; Humans; Hungary; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Patient Selection; Polymorphism, Genetic; Retrospective Studies; Risk Factors; Vitamin B 12 | 2006 |
Total homocysteine, folate, and cobalamin, and their relation to genetic polymorphisms, lifestyle and body mass index in healthy children and adolescents.
Topics: Adolescent; Aging; Blood Pressure; Body Mass Index; Child; Child, Preschool; Cholesterol; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Sex Characteristics; Triglycerides; Vitamin B 12 | 2006 |
Maternal hyperhomocysteinaemia is a risk factor for congenital heart disease.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Heart Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Maternal Age; Pregnancy; Pregnancy Complications; Risk Factors; Statistics, Nonparametric; Vitamin B 12 | 2006 |
A simple, convenient method to synthesize cobalamins: synthesis of homocysteinylcobalamin, N-acetylcysteinylcobalamin, 2-N-acetylamino-2-carbomethoxyethanethiolatocobalamin, sulfitocobalamin and nitrocobalamin.
Topics: Crystallography, X-Ray; Cysteine; Homocysteine; Molecular Structure; Vitamin B 12 | 2006 |
Plasma vitamin values and antiepileptic therapy: case reports of pregnancy outcomes affected by a neural tube defect.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Valproic Acid; Vitamin B 12; Vitamin B 6 | 2007 |
Dietary intake of B-vitamins in mothers born a child with a congenital heart defect.
Topics: Adult; Case-Control Studies; Dietary Proteins; Educational Status; Female; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Logistic Models; Maternal Nutritional Physiological Phenomena; Nutritional Requirements; Nutritional Status; Pregnancy; Pregnancy Complications; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex | 2006 |
Consequences of subchronic and chronic exposure to intermittent hypoxia and sleep deprivation on cardiovascular risk factors in rats.
Topics: Animals; Blood Gas Analysis; Body Weight; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Chronic Disease; Cysteine; Folic Acid; Homocysteine; Hypoxia; Male; Rats; Rats, Wistar; Risk Factors; Sleep Apnea Syndromes; Sleep Deprivation; Sleep, REM; Triglycerides; Vitamin B 12 | 2007 |
The association of homocysteine and its determinants MTHFR genotype, folate, vitamin B12 and vitamin B6 with bone mineral density in postmenopausal British women.
Topics: Aged; Alcohol Drinking; Bone Density; Female; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Osteoporosis, Postmenopausal; Polymorphism, Genetic; Postmenopause; Smoking; Vitamin B 12; Vitamin B 6; White People | 2007 |
Assessing the association between vitamin B-12 status and cognitive function in older adults.
Topics: Aged; Cognition; Health Status; Homocysteine; Humans; Mass Screening; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2006 |
Homocysteine, folate, and vitamin B-12 and cognitive performance in older Chinese adults: findings from the Singapore Longitudinal Ageing Study.
Topics: Aged; Aged, 80 and over; Aging; China; Cognition; Female; Folic Acid; Homocysteine; Humans; Linear Models; Longitudinal Studies; Male; Middle Aged; Psychological Tests; Singapore; Vitamin B 12; Vitamin B Complex | 2006 |
Biomarkers of folate and vitamin B12 are related in blood and cerebrospinal fluid.
Topics: Adult; Aged; Aging; Biomarkers; Cystathionine; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12 | 2007 |
Gene polymorphisms of folate metabolizing enzymes and the risk of gastric cancer.
Topics: Aged; Carboxypeptidases; Case-Control Studies; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Stomach Neoplasms; Vitamin B 12 | 2007 |
Folic acid fortification: the good, the bad, and the puzzle of vitamin B-12.
Topics: Cognition Disorders; Dose-Response Relationship, Drug; Folic Acid; Food, Fortified; Homocysteine; Humans; Immune System; Neoplasms; Nutrition Policy; Vitamin B 12; Vitamin B Complex | 2007 |
Plasma B vitamins and their relation to the severity of chronic heart failure.
Topics: Aged; Cardiac Catheterization; Echocardiography; Female; Folic Acid; Folic Acid Deficiency; Heart Failure; Homocysteine; Humans; Liver; Male; Middle Aged; Multivariate Analysis; Severity of Illness Index; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2007 |
Hyperhomocysteinemia as a cardiovascular risk factor in Indian women: determinants and directionality.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Middle Aged; Risk Assessment; Risk Factors; Vitamin B 12 | 2006 |
Glomerular filtration rate as measured by serum cystatin C is an important determinant of plasma homocysteine and serum methylmalonic acid in the elderly.
Topics: Aged; Avitaminosis; Biomarkers; Creatinine; Cystatin C; Cystatins; Female; Folic Acid; Folic Acid Deficiency; Glomerular Filtration Rate; Homocysteine; Humans; Kidney; Male; Methylmalonic Acid; Nutritional Status; Regression Analysis; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2007 |
Homocysteine concentrations and molecular analysis in patients with congenital heart defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Alleles; Carbon-Nitrogen Ligases; Child, Preschool; Cystathionine beta-Synthase; Female; Folic Acid; Gene Frequency; Heart Defects, Congenital; Homocysteine; Humans; Male; Mutation; Vitamin B 12 | 2007 |
B-group vitamins, MTHFR C677T polymorphism and carotid intima-media thickness in clinically healthy subjects.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Carbon-Nitrogen Ligases; Carotid Arteries; Carotid Artery Diseases; Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Genetic; Risk Factors; Sex Factors; Tunica Intima; Vitamin B 12; Vitamin B Complex | 2007 |
High prevalence of hyperhomocysteinemia in Chinese adults is associated with low folate, vitamin B-12, and vitamin B-6 status.
Topics: Adult; China; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Prevalence; Risk Factors; Seasons; Vitamin B 12; Vitamin B 6 | 2007 |
Association of methylenetetrahydrofolate (MTHFR) and apolipoprotein E (apo E) genotypes with homocysteine, vitamin and lipid levels in carotid stenosis.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Apolipoproteins E; Carotid Stenosis; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Male; Middle Aged; Mutation; Vitamin B 12 | 2006 |
Hyperhomocysteinaemia and immune activation in patients with cancer.
Topics: Aged; Biomarkers; Case-Control Studies; Cysteine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immune System; Male; Neoplasms; Neopterin; Vitamin B 12 | 2007 |
The effect of homocysteine reduction by B-vitamin supplementation on inflammatory markers.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Chemokine CCL2; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Inflammation; Interleukin-6; Interleukin-8; Male; Middle Aged; Vitamin B 12; Vitamin B 6 | 2007 |
Elevated serum homocysteine, low serum vitamin B12, folate, and age-related macular degeneration: the Blue Mountains Eye Study.
Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Fluorescence Polarization Immunoassay; Folic Acid; Homocysteine; Humans; Macular Degeneration; Male; Middle Aged; New South Wales; Odds Ratio; Risk Factors; Vitamin B 12 | 2007 |
Plasma homocysteine levels in female patients with eating disorders.
Topics: Adolescent; Adult; Bone Density; Feeding and Eating Disorders; Female; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 2007 |
Altered renal folate handling in hypertensive patients with nephroangiosclerotic damage.
Topics: Case-Control Studies; Creatinine; Folic Acid; Genotype; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension, Renal; Ischemia; Methylenetetrahydrofolate Reductase (NADPH2); Nephrons; Renal Artery Obstruction; Vitamin B 12 | 2007 |
Abnormalities of homocysteine and B vitamins in the nephrotic syndrome.
Topics: Adult; Antibodies, Antiphospholipid; Antithrombins; Factor V; Female; Folic Acid; Homocysteine; Humans; Hyperlipidemias; Hypertension; Male; Middle Aged; Nephrotic Syndrome; Risk; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Associations of MTHFR DNMT3b 4977 bp deletion in mtDNA and GSTM1 deletion, and aberrant CpG island hypermethylation of GSTM1 in non-obstructive infertility in Indian men.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Base Sequence; Case-Control Studies; CpG Islands; Deoxyguanosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; DNA, Mitochondrial; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Glutathione Transferase; Homocysteine; Humans; India; Infertility, Male; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Sequence Deletion; Vitamin B 12; White People | 2007 |
Cardiovascular fitness is negatively associated with homocysteine levels in female adolescents.
Topics: Adolescent; Cardiovascular Physiological Phenomena; Exercise Test; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Physical Fitness; Polymorphism, Genetic; Regression Analysis; Sex Distribution; Sex Factors; Spain; Vitamin B 12 | 2007 |
Modulation of the homocysteine-betaine relationship by methylenetetrahydrofolate reductase 677 C->t genotypes and B-vitamin status in a large-scale epidemiological study.
Topics: Betaine; Choline; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamins | 2007 |
Homocysteine, B vitamins, and the risk of dementia.
Topics: Clinical Trials as Topic; Dementia; Homocysteine; Humans; Risk Factors; Vitamin B 12 | 2007 |
Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on Aging.
Topics: Aged; Aged, 80 and over; Aging; California; Cognition Disorders; Dementia; Disease Susceptibility; Female; Folic Acid; Health Surveys; Hispanic or Latino; Homocysteine; Humans; Incidence; Male; Middle Aged; Risk Factors; Stroke; Vitamin B 12 | 2007 |
Medical-process patents.
Topics: Delivery of Health Care; Genetic Predisposition to Disease; Homocysteine; Humans; Patents as Topic; Pharmacogenetics; Supreme Court Decisions; United States; Vitamin B 12 | 2007 |
Associations between folate, vitamin B12, homocysteine and pathologies related to aging: the need to consider complex nutrient-nutrient and gene-nutrient interactions and the functional and socio-economic determinants in population-based studies.
Topics: Aging; Epidemiology; Folic Acid; Food; Genes; Homocysteine; Humans; Socioeconomic Factors; Vitamin B 12 | 2007 |
Association of vitamin B12, folate and homocysteine with functional and pathological characteristics of the elderly in a mountainous village in Sicily.
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Diabetes Mellitus; Folic Acid; Homocysteine; Humans; Middle Aged; Neoplasms; Peripheral Vascular Diseases; Sicily; Stroke; Vitamin B 12 | 2007 |
Association of thyroid dysfunction with vitamin B12, folate and plasma homocysteine levels in the elderly: a population-based study in Sicily.
Topics: Aged; Aged, 80 and over; Aging; Epidemiology; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Sicily; Thyroid Diseases; Vitamin B 12 | 2007 |
Renal impairment compromises the use of total homocysteine and methylmalonic acid but not total vitamin B12 and holotranscobalamin in screening for vitamin B12 deficiency in the aged.
Topics: Aged; Aged, 80 and over; Homocysteine; Humans; Kidney Diseases; Methods; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Correlation of folate, vitamin B12 and homocysteine plasma levels with depression in an elderly Greek population.
Topics: Aged; Depression; Female; Folic Acid; Greece; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12 | 2007 |
Maternal vitamin B12 and the risk of fetal neural tube defects in Egyptian patients.
Topics: Case-Control Studies; Egypt; Female; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Neural Tube Defects; Odds Ratio; Pregnancy; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
By the way, doctor. How do B vitamins lower your homocysteine level, and how important is it to have a normal level?
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Holotranscobalamin and methylmalonic acid as prognostic markers following an acute myocardial infarction.
Topics: Acute Disease; Aged; Aged, 80 and over; Biomarkers; Female; Follow-Up Studies; Homocysteine; Humans; Male; Methylmalonic Acid; Myocardial Infarction; Odds Ratio; Prognosis; Recurrence; Time Factors; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Total cardiovascular risk profile of Taiwanese vegetarians.
Topics: C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Cholesterol; Diet, Vegetarian; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutritional Status; Risk Assessment; Risk Factors; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Serum homocysteine, folate, vitamin B12 and total antioxidant status in vegetarian children.
Topics: Antioxidants; Child; Child, Preschool; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Male; Nutrition Policy; Nutritional Status; Vitamin B 12 | 2006 |
Homocysteine increases the risk of mortality in elderly individuals.
Topics: Aged; Aging; Biomarkers; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Mortality; Selenium; Spain; Survival Analysis; Vitamin B 12 | 2007 |
Folate status and risk of colorectal polyps in African Americans.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Black or African American; Case-Control Studies; Colonic Polyps; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Genes, APC; Homocysteine; Humans; Male; Middle Aged; Promoter Regions, Genetic; Smoking; Tetrahydrofolates; Vitamin B 12; Vitamins | 2007 |
Polymorphisms in methionine synthase reductase and betaine-homocysteine S-methyltransferase genes: risk of placental abruption.
Topics: Abruptio Placentae; Adolescent; Adult; Betaine-Homocysteine S-Methyltransferase; Case-Control Studies; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Polymorphism, Genetic; Pregnancy; Risk Factors; Vitamin B 12 | 2007 |
Hyperhomocysteinemia and low methionine stress are risk factors for central retinal venous occlusion in an Indian population.
Topics: Adult; Case-Control Studies; Cysteine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methionine; Prevalence; Prospective Studies; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2007 |
Low vitamin B6, and not plasma homocysteine concentration, as risk factor for abdominal aortic aneurysm: a retrospective case-control study.
Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Case-Control Studies; Creatinine; DNA Mutational Analysis; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Genetic; Retrospective Studies; Risk Assessment; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B 6 Deficiency | 2007 |
Acute effects of tea on fasting and non-fasting plasma total homocysteine concentrations in human subjects.
Topics: Aged; Biomarkers; Caffeine; Cross-Over Studies; Drinking; Eating; Fasting; Female; Flavonoids; Folic Acid; Gallic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Phenols; Polyphenols; Tea; Vitamin B 12 | 2007 |
MTHFR Gene polymorphisms, B-vitamins and hyperhomocystinemia in young and middle-aged acute myocardial infarction patients.
Topics: Adult; Age Factors; Diet; Dietary Supplements; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Infarction; Polymorphism, Single Nucleotide; Riboflavin; Vitamin B 12; Vitamin B Complex | 2007 |
The methylenetetrahydrofolate reductase 677C-->T polymorphism as a modulator of a B vitamin network with major effects on homocysteine metabolism.
Topics: Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Polymorphism, Single Nucleotide; Riboflavin; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
[Correlation between serum homocysteine levels and selected atherosclerosis risk factors in children and adolescents with simple obesity].
Topics: Adolescent; Atherosclerosis; Biomarkers; Body Mass Index; Child; Comorbidity; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hypertension; Male; Obesity; Obesity, Morbid; Poland; Risk Factors; Statistics, Nonparametric; Vitamin B 12 | 2006 |
The association of homocysteine and related factors to brachial artery diameter and flow-mediated dilation.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Aged; Brachial Artery; Cardiovascular Diseases; Dilatation, Pathologic; DNA; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Point Mutation; Polymerase Chain Reaction; Ultrasonography; Vitamin B 12; Vitamin B 6 | 2007 |
Homocysteine in tear fluid of patients with pseudoexfoliation glaucoma.
Topics: Aged; Chromatography, High Pressure Liquid; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Homocysteine; Humans; Male; Plasma; Tears; Vitamin B 12 | 2007 |
Preconception B-vitamin and homocysteine status, conception, and early pregnancy loss.
Topics: Abortion, Spontaneous; Adult; China; Chorionic Gonadotropin; Female; Fertilization; Folic Acid; Homocysteine; Humans; Odds Ratio; Preconception Care; Pregnancy; Prospective Studies; Risk Assessment; Risk Factors; Vitamin B 12; Vitamin B 6 | 2007 |
Neuropsychological correlates of homocysteine levels in euthymic bipolar patients.
Topics: Adolescent; Adult; Bipolar Disorder; Cognition; Cognition Disorders; Dysthymic Disorder; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Severity of Illness Index; Vitamin B 12 | 2008 |
Beer ethanol consumption and plasma homocysteine among patients with type 2 diabetes.
Topics: Alcohol Drinking; Beer; Diabetes Mellitus, Type 2; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Regression Analysis; Vitamin B 12 | 2007 |
Association between decreased vitamin levels and MTHFR, MTR and MTRR gene polymorphisms as determinants for elevated total homocysteine concentrations in pregnant women.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Alleles; Analysis of Variance; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Young Adult | 2008 |
Cobalamin deficiency-induced down-regulation of p75-immunoreactive cell levels in rat central nervous system.
Topics: Animals; Central Nervous System; Down-Regulation; Gastrectomy; Homocysteine; Immunohistochemistry; Male; Methylmalonic Acid; Nerve Fibers, Myelinated; Nerve Growth Factor; Rats; Rats, Sprague-Dawley; Receptor, Nerve Growth Factor; Recovery of Function; Septal Nuclei; Spinal Cord; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Relations between homocysteine, folate and vitamin B12 in vascular dementia and in Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Risk Factors; Vitamin B 12 | 2007 |
Secondary palatal closure in rats in association with relative maternofetal levels of folic acid, vitamin B12, and homocysteine.
Topics: Animals; Embryonic Development; Female; Folic Acid; Homocysteine; Maternal-Fetal Exchange; Palate; Pregnancy; Rats; Rats, Inbred Lew; Vitamin B 12 | 2007 |
Dietary intake of B(6-9-12) vitamins, serum homocysteine levels and their association with depressive symptoms: the Zutphen Elderly Study.
Topics: Aged; Aged, 80 and over; Depression; Diet; Folic Acid; Homocysteine; Humans; Linear Models; Logistic Models; Male; Nutritional Requirements; Nutritional Status; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2008 |
Priorities in the discovery of the implications of water channels in epilepsy and Duchenne muscular dystrophy.
Topics: Aquaporins; Brain; Epilepsy; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Muscular Dystrophy, Duchenne; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Plasma folate, vitamin B6, vitamin B12, and homocysteine and pancreatic cancer risk in four large cohorts.
Topics: Adult; Case-Control Studies; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Pancreatic Neoplasms; Risk Factors; Vitamin B 12; Vitamin B 6 | 2007 |
Can B vitamin therapy help to prevent future vascular events?
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12 | 2007 |
Homocysteine and fibrinogen changes with L-thyroxine in subclinical hypothyroid patients.
Topics: Adult; Case-Control Studies; Female; Fibrinogen; Folic Acid; Homocysteine; Humans; Hypothyroidism; Kidney; Middle Aged; Thyrotropin; Thyroxine; Triiodothyronine; Vitamin B 12 | 2007 |
Mild hyperhomocysteinemia and low folate concentrations as risk factors for cervical arterial dissection.
Topics: Adolescent; Adult; Carotid Artery, Internal, Dissection; Case-Control Studies; Cerebral Arteries; Cerebral Infarction; Fasting; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mexico; Middle Aged; Nutritional Status; Odds Ratio; Polymorphism, Genetic; Prospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Vertebral Artery Dissection; Vitamin B 12 | 2007 |
Plasma homocysteine, folate and B12 in chronic schizophrenia.
Topics: Adult; Age Factors; Aged; Analysis of Variance; Chi-Square Distribution; Chronic Disease; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Schizophrenia; Sex Factors; Vitamin B 12 | 2007 |
Reference intervals for haematological variables during normal pregnancy and postpartum in 434 healthy Danish women.
Topics: Creatinine; Denmark; Female; Ferritins; Folic Acid; Hematologic Tests; Homocysteine; Humans; Methylmalonic Acid; Postpartum Period; Pregnancy; Receptors, Transferrin; Reference Values; Vitamin B 12 | 2007 |
Influence of different dietary levels of zinc on performance, vitamin B12, and blood parameters in lambs.
Topics: Animal Feed; Animals; Blood Glucose; Body Weight; Cobalt; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Methylmalonic Acid; Rumen; Sheep; Vitamin B 12; Zinc | 2006 |
2756GG genotype of methionine synthase reductase gene is more prevalent in rheumatoid arthritis patients treated with methotrexate and is associated with methotrexate-induced nodulosis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Case-Control Studies; Cross-Sectional Studies; Female; Ferredoxin-NADP Reductase; Genotype; Homocysteine; Humans; Male; Methotrexate; Middle Aged; Polymorphism, Single Nucleotide; Pteroylpolyglutamic Acids; Rheumatic Nodule; Severity of Illness Index; Vitamin B 12 | 2007 |
Folate, but not vitamin B-12 status, predicts respiratory morbidity in north Indian children.
Topics: Acute Disease; Child, Preschool; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Incidence; India; Infant; Male; Methylmalonic Acid; Multivariate Analysis; Prospective Studies; Regression Analysis; Respiratory Tract Infections; Risk Factors; Vitamin B 12 | 2007 |
Relationship between dietary folate intakes, maternal plasma total homocysteine and B-vitamins during pregnancy and fetal growth in Japan.
Topics: Adult; Biomarkers; Birth Weight; Body Mass Index; Erythrocytes; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Infant, Newborn; Japan; Male; Nutritional Status; Parity; Pregnancy; Pregnancy Outcome; Vitamin B 12; Vitamin B Complex | 2007 |
Correlations between folate, B12, homocysteine levels, and radiological markers of neuropathology in elderly post-stroke patients.
Topics: Aged; Biomarkers; Brain; Brain Infarction; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Mental Recall; Nutrition Assessment; Nutrition Policy; Stroke; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex | 2007 |
The heritability of plasma homocysteine, and the influence of genetic variation in the homocysteine methylation pathway.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Aged; Diseases in Twins; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Ischemia; Polymorphism, Single Nucleotide; Surveys and Questionnaires; Vitamin B 12 | 2007 |
Elevated plasma homocysteine concentration in elderly patients with mental illness is mainly related to the presence of vascular disease and not the diagnosis.
Topics: Aged; Aged, 80 and over; Aging; Creatinine; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Kidney Function Tests; Male; Mental Disorders; Psychiatric Status Rating Scales; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Elevated homocysteine levels in patients with slow coronary flow: relationship with Helicobacter pylori infection.
Topics: Adult; Blood Flow Velocity; Cardiovascular Diseases; Coronary Circulation; Female; Folic Acid; Helicobacter Infections; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2007 |
Accumulation of homocysteine by decreasing concentrations of folate, vitamin B12 and B6 does not influence the activity of human osteoblasts in vitro.
Topics: Calcification, Physiologic; Cells, Cultured; Folic Acid; Homocysteine; Humans; Osteoblasts; Osteocalcin; Peptide Fragments; Procollagen; Vitamin B 12; Vitamin B 6 | 2007 |
B-vitamins and homocysteine in Spanish institutionalized elderly.
Topics: Aged; Aged, 80 and over; Aging; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Institutionalization; Male; Middle Aged; Regression Analysis; Sex Characteristics; Spain; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamin B Deficiency | 2007 |
[Vitamin B12 therapy: oral or intramuscular].
Topics: Administration, Oral; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Injections, Intramuscular; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Homocysteine, folic acid and vitamin B12 concentration in patients with recurrent miscarriages.
Topics: Abortion, Habitual; Adult; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Vitamin B 12 | 2007 |
The MTHFR 677 C/T polymorphism influences plasma levels of adhesion molecules and nitric oxide.
Topics: Adult; Aged; Cell Adhesion Molecules; E-Selectin; Female; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nitric Oxide; Polymorphism, Genetic; Vascular Cell Adhesion Molecule-1; Vitamin B 12; Vitamin B 6 | 2008 |
[Effects of folic acid, vitamin B(6) and vitamin B(12) on learning and memory function in cerebral ischemia rats].
Topics: Animals; Brain Ischemia; Disease Models, Animal; Female; Folic Acid; Homocysteine; Infarction, Middle Cerebral Artery; Learning; Male; Memory; Rats; Rats, Sprague-Dawley; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Effects of concentrations of cyanocobalamin in the gestation diet on some criteria of vitamin B12 metabolism in first-parity sows.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Colostrum; Dietary Supplements; Dose-Response Relationship, Drug; Female; Homocysteine; Lactation; Parity; Pregnancy; Pregnancy, Animal; Random Allocation; Swine; Vitamin B 12 | 2007 |
Homocysteine (Hcy) follow-up study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atherosclerosis; Coronary Artery Disease; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Risk Factors; Sex Factors; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2007 |
[Antibodies to N-homocysteinylated albumin in patients with systemic lupus erythematosus].
Topics: Adolescent; Adult; Autoantibodies; C-Reactive Protein; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Serum Albumin; Vitamin B 12 | 2007 |
Effects of white European, African Caribbean and South Asian ethnicity on homocysteine levels in patients with systolic heart failure.
Topics: Aged; Asia, Southeastern; Asian People; Black People; Ethnicity; Female; Folic Acid; Heart Failure, Systolic; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12; West Indies; White People | 2008 |
Influence of preconditioning-like hypoxia on the liver of developing methyl-deficient rats.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Proliferation; Choline Deficiency; Cystathionine beta-Synthase; Female; Folic Acid; Folic Acid Deficiency; Food, Formulated; Glutathione; Homocysteine; Hypoxia; Liver; Nitric Oxide Synthase Type II; Pregnancy; Rats; Rats, Wistar; Riboflavin; Riboflavin Deficiency; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Deficiency | 2007 |
Marfanoid features in a child with combined methylmalonic aciduria and homocystinuria (CblC type).
Topics: Adolescent; Carnitine; Carrier Proteins; Child; Cysteine; Diagnosis, Differential; DNA Mutational Analysis; Exons; Female; Folic Acid; Genetic Testing; Heterozygote; Homocysteine; Homocystinuria; Humans; Male; Marfan Syndrome; Metabolism, Inborn Errors; Methylmalonic Acid; Mutation; Oxidoreductases; Pedigree; Phenotype; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamins | 2007 |
Helicobacter pylori may be involved in cognitive impairment and dementia development through induction of atrophic gastritis, vitamin B-12 folate deficiency, and hyperhomocysteinemia sequence.
Topics: Aged; Aged, 80 and over; Aging; Cognition Disorders; Dementia; Folic Acid Deficiency; Gastritis, Atrophic; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
[Serum homocysteine, folate and vitamin B12 in venezuelan elderly].
Topics: Aged; Aged, 80 and over; Body Mass Index; Energy Intake; Female; Folic Acid; Folic Acid Deficiency; Hematocrit; Hemoglobins; Homocysteine; Humans; Male; Middle Aged; Reference Values; Venezuela; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Dietary intake and status of folate and vitamin B12 and their association with homocysteine and cardiovascular disease in European populations.
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Diet; Europe; Folic Acid; Homocysteine; Humans; Middle Aged; Nutritional Requirements; Vitamin B 12; Young Adult | 2009 |
Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study.
Topics: Adipose Tissue; Anthropometry; Body Composition; Body Mass Index; Child; Female; Folic Acid; Homocysteine; Humans; Insulin Resistance; Male; Methylmalonic Acid; Pregnancy; Pregnancy Complications; Vitamin B 12 | 2008 |
Experimental hyperhomocysteinemia disturbs bone metabolism in rats.
Topics: Animals; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Collagen Type I; Creatine; Female; Folic Acid; Homocysteine; Hydroxyproline; Hyperhomocysteinemia; Methionine; Osteocalcin; Osteogenesis; Peptides; Rats; Rats, Wistar; Vitamin B 12 | 2007 |
Homocysteine, folate and vitamin B12 in Colombian patients with coronary disease.
Topics: Acute Coronary Syndrome; Adult; Biomarkers; Colombia; Epidemiologic Methods; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Middle Aged; Vitamin B 12 | 2007 |
Homocysteine in restless legs syndrome.
Topics: Aged; Antiparkinson Agents; Catechols; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Reference Values; Restless Legs Syndrome; Vitamin B 12; Vitamin B 6 | 2008 |
Plasma creatinine as a determinant of plasma total homocysteine concentrations in the Hordaland Homocysteine Study: use of statistical modeling to determine reference limits.
Topics: Adult; Age Factors; Aged; Creatinine; Female; Folic Acid; Homocysteine; Humans; Kidney Function Tests; Male; Middle Aged; Models, Statistical; Sex Factors; Vitamin B 12 | 2007 |
Associations between 2 polymorphisms in the methylenetetrahydrofolate reductase gene and placental abruption.
Topics: Abruptio Placentae; Adolescent; Adult; Alleles; Case-Control Studies; DNA; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Linkage Disequilibrium; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pregnancy; Social Class; Vitamin B 12 | 2007 |
Effect of MTHFR polymorphisms on hyperhomocysteinemia in levodopa-treated Parkinsonian patients.
Topics: Aged; Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic; Vitamin B 12 | 2007 |
Methylation of estrogen receptor alpha and mutL homolog 1 in normal colonic mucosa: association with folate and vitamin B-12 status in subjects with and without colorectal neoplasia.
Topics: Adaptor Proteins, Signal Transducing; Adenoma; Aged; Base Sequence; Biomarkers; Case-Control Studies; Colon; Colonic Polyps; Colorectal Neoplasms; DNA Methylation; Erythrocytes; Estrogen Receptor alpha; Female; Folic Acid; Homocysteine; Humans; Intestinal Mucosa; Male; Middle Aged; MutL Protein Homolog 1; Nuclear Proteins; Nutritional Status; Vitamin B 12 | 2007 |
Oral challenge with a methionine load in patients with inflammatory bowel disease: a better test to identify hyperhomocysteinemia.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Inflammatory Bowel Diseases; Male; Methionine; Middle Aged; Prevalence; Prognosis; Prospective Studies; Risk Factors; Thrombosis; Vitamin B 12 | 2008 |
Methylenetetrahydrofolate reductase gene and risk of Alzheimer's disease in Koreans.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Asian People; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors; Vitamin B 12 | 2008 |
Determinants of arsenic metabolism: blood arsenic metabolites, plasma folate, cobalamin, and homocysteine concentrations in maternal-newborn pairs.
Topics: Adult; Arsenic; Arsenic Poisoning; Bangladesh; Biomarkers; Cohort Studies; Environmental Exposure; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Vitamin B 12; Water Supply | 2007 |
Low vitamin B6 and folic acid levels are associated with retinal vein occlusion independently of homocysteine levels.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Radioimmunoassay; Retinal Vein Occlusion; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B 6 Deficiency | 2008 |
Impaired vitamin B12 metabolic status in healthcare workers occupationally exposed to nitrous oxide.
Topics: Adult; Anesthetics, Inhalation; Blood Specimen Collection; Dose-Response Relationship, Drug; Environmental Monitoring; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Nitrous Oxide; Occupational Exposure; Operating Room Nursing; Operating Rooms; Ventilation; Vitamin B 12 | 2007 |
Low vitamin B-12 status and risk of cognitive decline in older adults.
Topics: Aged; Aged, 80 and over; Cognition Disorders; Cohort Studies; Female; Homocysteine; Humans; Longitudinal Studies; Male; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Effect of a voluntary food fortification policy on folate, related B vitamin status, and homocysteine in healthy adults.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Erythrocytes; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Middle Aged; Neural Tube Defects; Nutrition Policy; Nutritional Status; Vitamin B 12; Vitamin B 6 | 2007 |
Association of blood pressure, obesity and serum homocysteine levels in healthy children.
Topics: Adolescent; Age Factors; Analysis of Variance; Blood Pressure; Body Mass Index; Child; Energy Intake; Female; Folic Acid; Greece; Homocysteine; Humans; Male; Obesity; Overweight; Regression Analysis; Risk Factors; Vitamin B 12 | 2007 |
The association of gastric cancer risk with plasma folate, cobalamin, and methylenetetrahydrofolate reductase polymorphisms in the European Prospective Investigation into Cancer and Nutrition.
Topics: Adult; Aged; Case-Control Studies; Cohort Studies; Europe; Female; Folic Acid; Gastritis, Atrophic; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Polymorphism, Single Nucleotide; Prospective Studies; Risk Factors; Stomach Neoplasms; Vitamin B 12 | 2007 |
Evaluation of nutritional and genetic determinants of total homocysteine, methylmalonic acid and S-adenosylmethionine/S-adenosylhomocysteine values in Brazilian childbearing-age women.
Topics: Adult; Aging; Alleles; Anemia, Iron-Deficiency; Avitaminosis; Brazil; Female; Genotype; Homocysteine; Humans; Methylmalonic Acid; Nutritional Physiological Phenomena; Polymorphism, Genetic; Reproduction; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamins | 2008 |
Growth-related changes of parameters of the methylation cycle and jejunal aminopeptidase M in the rat.
Topics: Aging; Animals; CD13 Antigens; Female; Folic Acid; Growth; Homocysteine; Jejunum; Methylation; Rats; Rats, Inbred Lew; Vitamin B 12 | 2008 |
The 677 C/T MTHFR polymorphism is associated with essential hypertension, coronary artery disease, and higher homocysteine levels.
Topics: Aged; Coronary Artery Disease; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Turkey; Vitamin B 12 | 2008 |
Effect of folate, vitamin B6, and vitamin B12 intake and MTHFR C677T polymorphism on homocysteine concentrations of renal transplant recipients.
Topics: Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Kidney Transplantation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Postoperative Complications; Vitamin B 12; Vitamin B 6 | 2007 |
Methylmalonic acid values in healthy Dutch children.
Topics: Adolescent; Adult; Aging; Biomarkers; Child; Child, Preschool; Creatinine; Cross-Sectional Studies; Female; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methylmalonic Acid; Netherlands; Reference Values; Regression Analysis; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Plasma vitamin B12 concentrations and the risk of colorectal cancer: a nested case-referent study.
Topics: Adult; Aged; Analysis of Variance; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Prospective Studies; Risk Assessment; Risk Factors; Sweden; Vitamin B 12 | 2008 |
Homocysteine levels in epileptic children receiving antiepileptic drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Oxcarbazepine; Valproic Acid; Vitamin B 12 | 2007 |
Evidence for sex differences in the determinants of homocysteine concentrations.
Topics: Adult; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Regression Analysis; Sex Characteristics; Smoking; Vitamin B 12 | 2008 |
A comparison of some of the cardiovascular risk factors in vegetarian and omnivorous Turkish females.
Topics: Adult; Cardiovascular Diseases; Diet; Diet Records; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Nutritional Status; Risk Factors; Turkey; Vitamin B 12 | 2008 |
The effects of raloxifene and tibolone on homocysteine and vascular histopathological changes.
Topics: Animals; Atherosclerosis; Carotid Arteries; Estrogen Replacement Therapy; Female; Folic Acid; Homocysteine; Norpregnenes; Raloxifene Hydrochloride; Rats; Rats, Wistar; Vitamin B 12 | 2007 |
The effect of antiepileptic drugs on vitamin B12 metabolism.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Case-Control Studies; Epilepsy; Erythrocytes, Abnormal; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neutrophils; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Waist-to-hip ratio correlates with homocysteine levels in male patients with coronary artery disease.
Topics: Aged; Biomarkers; Body Mass Index; Coronary Artery Disease; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Obesity; Risk Factors; Vitamin B 12; Waist-Hip Ratio | 2008 |
Elevated plasma homocysteine levels in patients with amyotrophic lateral sclerosis.
Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Biomarkers; Central Nervous System; Comorbidity; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nerve Degeneration; Predictive Value of Tests; Risk Factors; Sensitivity and Specificity; Up-Regulation; Vitamin B 12 | 2008 |
Plasma S-adenosylhomocysteine is a better biomarker of atherosclerosis than homocysteine in apolipoprotein E-deficient mice fed high dietary methionine.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Biomarkers; Body Weight; Diet; DNA Methylation; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Male; Methionine; Mice; S-Adenosylhomocysteine; Vitamin B 12; Vitamin B 6 | 2008 |
Sport-related hyperhomocysteinaemia: a putative marker of muscular demand to be noted for cardiovascular risk.
Topics: Adult; Cardiovascular Diseases; Case-Control Studies; Cholesterol, HDL; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Interleukin-6; L-Lactate Dehydrogenase; Male; Muscle, Skeletal; Risk Factors; Sports; Vitamin B 12 | 2008 |
Methylenetetrahydrofolate reductase 677 T allele protects against persistent HBV infection in West Africa.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Alleles; Benin; Biomarkers; DNA; DNA Probes; DNA, Viral; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; HLA-DR Antigens; HLA-DRB1 Chains; Homocysteine; Humans; Immunoassay; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Morbidity; Polymerase Chain Reaction; Polymorphism, Genetic; Vitamin B 12 | 2008 |
B-vitamins and prevention of dementia.
Topics: Aged; Aged, 80 and over; Cognition; Dementia; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2008 |
Evaluation of the relationship between C677T variants of methylenetetrahydrofolate reductase gene and hyperhomocysteinemia in children receiving antiepileptic drug therapy.
Topics: Adolescent; Analysis of Variance; Anticonvulsants; Carbamazepine; Child; Chromatography, High Pressure Liquid; Electrochemistry; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Valproic Acid; Vitamin B 12 | 2008 |
Total plasma homocysteine correlates in women with gestational diabetes.
Topics: Adult; Case-Control Studies; Diabetes, Gestational; Female; Folic Acid; Homocysteine; Humans; Insulin Resistance; Pregnancy; Vitamin B 12 | 2008 |
Total homocysteine, B-vitamins and genetic polymorphisms in patients with classical phenylketonuria.
Topics: Adolescent; Adult; Body Mass Index; Child; Child, Preschool; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Phenylketonurias; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6; Vitamin B Deficiency | 2008 |
Changes in folate, vitamin B12 and homocysteine associated with incident dementia.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Dementia; Dementia, Vascular; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Mental Status Schedule; Neuropsychological Tests; Predictive Value of Tests; Prospective Studies; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Homocysteine concentration, related B vitamins, and betaine in pregnant women recruited to the Seychelles Child Development Study.
Topics: Adult; Betaine; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methionine; Parturition; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, Third; Seychelles; Vitamin B 12; Vitamin B Complex | 2008 |
Relation of folates, vitamin B12 and homocysteine to vertebral bone mineral density change in postmenopausal women. A five-year longitudinal evaluation.
Topics: Bone Density; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Middle Aged; Models, Biological; Postmenopause; Spine; Time Factors; Vitamin B 12 | 2008 |
Metal active site elasticity linked to activation of homocysteine in methionine synthases.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Binding Sites; Catalysis; Crystallography, X-Ray; Elasticity; Homocysteine; Metals; Methylation; Methyltransferases; Protein Conformation; Thermotoga maritima; Vitamin B 12; Zinc | 2008 |
Elevated plasma homocysteine and low vitamin B-6 status in nonsupplementing older women with rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Cross-Sectional Studies; Diet Records; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Complex | 2008 |
Protective effect against alcohol dependence of the thermolabile variant of MTHFR.
Topics: Alcohol Drinking; Alcoholic Neuropathy; Alcoholism; Control Groups; Female; Folic Acid; Folic Acid Deficiency; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk; Vitamin B 12 | 2008 |
The methylenetetrahydrofolate reductase 677C>T gene polymorphism is not associated with chronic plaque psoriasis.
Topics: Adult; Austria; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Psoriasis; Vitamin B 12; White People | 2008 |
Homocysteine or renal impairment: which is the real cardiovascular risk factor?
Topics: Aged; Aged, 80 and over; Biomarkers; Brachial Artery; Cardiovascular Diseases; Carotid Arteries; Cross-Sectional Studies; Cystatin C; Cystatins; Female; Folic Acid; Follow-Up Studies; Glomerular Filtration Rate; Homocysteine; Humans; Kidney Diseases; Male; Middle Aged; Predictive Value of Tests; Regional Blood Flow; Regression Analysis; Risk Factors; Vitamin B 12; Vitamin B 6 | 2008 |
Homocysteine, vitamin B12 and folate status in pediatric acute lymphoblastic leukemia.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Discriminant Analysis; Female; Folic Acid; Homocysteine; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vitamin B 12 | 2008 |
Plasma homocysteine, vitamin B12 and folate levels in hydatidiform moles and histopathological subtypes.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hydatidiform Mole; Pregnancy; Statistics, Nonparametric; Uterine Neoplasms; Vitamin B 12 | 2008 |
Genetic polymorphism of MTHFR G1793A in Chinese populations.
Topics: Asian People; Case-Control Studies; China; Ethnicity; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Linkage Disequilibrium; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Population; Prevalence; Vitamin B 12 | 2008 |
Polymorphisms in genes related to folate and cobalamin metabolism and the associations with complex birth defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Amniotic Fluid; Case-Control Studies; Child; Congenital Abnormalities; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Risk Factors; Transcobalamins; Vitamin B 12 | 2008 |
Folic acid protects motor neurons against the increased homocysteine, inflammation and apoptosis in SOD1 G93A transgenic mice.
Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Folic Acid; Gas Chromatography-Mass Spectrometry; Homocysteine; Inflammation; Mice; Mice, Transgenic; Motor Neurons; Nitric Oxide Synthase Type II; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rotarod Performance Test; Spinal Cord; Superoxide Dismutase; Vitamin B 12; Vitamin B Complex | 2008 |
Reduced urinary excretion of homocysteine could be the reason of elevated plasma homocysteine in patients with psychiatric illnesses.
Topics: Acute Disease; Adult; Biomarkers; Chronic Disease; Female; Folic Acid; Homocysteine; Humans; Male; Meta-Analysis as Topic; Middle Aged; Psychotic Disorders; Vitamin B 12 | 2008 |
Homocysteine-lowering B vitamin therapy in cardiovascular prevention--wrong again?
Topics: Cardiovascular Diseases; Dietary Supplements; Folic Acid; Homocysteine; Humans; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
CSF/serum folate gradient: physiology and determinants with special reference to dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blood-Brain Barrier; Case-Control Studies; Choroid Plexus; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Risk Factors; Serum Albumin; Vitamin B 12 | 2008 |
Evaluation of the levels of folate, vitamin B12, homocysteine and fluoride in the parents and the affected neonates with neural tube defect and their matched controls.
Topics: Biomarkers; Female; Fluorides; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Incidence; India; Infant, Newborn; Male; Neural Tube Defects; Parents; Prognosis; Retrospective Studies; Risk Factors; Vitamin B 12 | 2008 |
Relationship between serum nickel and homocysteine concentration in hemodialysis patients.
Topics: Aged; C-Reactive Protein; Female; Homocysteine; Humans; Interleukin-6; Male; Middle Aged; Nickel; Regression Analysis; Renal Dialysis; Trace Elements; Vitamin B 12 | 2008 |
Traffic-related particles are associated with elevated homocysteine: the VA normative aging study.
Topics: Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Biomarkers; Carbon; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Particulate Matter; Sulfur; Vehicle Emissions; Vitamin B 12 | 2008 |
Reduction of the genomic damage level in haemodialysis patients by folic acid and vitamin B12 supplementation.
Topics: Aged; Aged, 80 and over; Case-Control Studies; DNA Damage; Female; Folic Acid; Genome, Human; Homocysteine; Humans; Kidney Failure, Chronic; Lymphocytes; Male; Micronucleus Tests; Middle Aged; Neoplasms; Prospective Studies; Renal Dialysis; Vitamin B 12 | 2008 |
Plasma homocysteine, but not folate or vitamin B-12, predicts mortality in older people in the United Kingdom.
Topics: Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Male; Risk Factors; United Kingdom; Vitamin B 12 | 2008 |
The homocysteine paradox.
Topics: Animals; Arginine; Cardiovascular Diseases; Cystatin C; Cystatins; Disease Models, Animal; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Risk Factors; Vitamin B 12; Vitamin B 6 | 2008 |
Pilot study of homocysteine and cysteine in patients with thrombosis in different vascular sites. Epidemiology and response to folate.
Topics: Adult; Aged; Cysteine; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pilot Projects; Thrombosis; Vitamin B 12 | 2009 |
Changes in predictors and status of homocysteine in young male adults after a dietary intervention with vegetables, fruits and bread.
Topics: Adolescent; Adult; Bread; Folic Acid; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Male; Norway; Riboflavin; Surveys and Questionnaires; Treatment Outcome; Vegetables; Vitamin B 12; Vitamin B Complex | 2008 |
Maternal serum vitamin B12, folate and homocysteine and the risk of neural tube defects in the offspring in a high-risk area of China.
Topics: Adult; Case-Control Studies; China; Diet; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Luminescent Measurements; Maternal Nutritional Physiological Phenomena; Neural Tube Defects; Pregnancy; Pregnant Women; Risk Factors; Ultrasonography; Vitamin B 12; Young Adult | 2009 |
Homocysteine and related B-vitamin status in coeliac disease: Effects of gluten exclusion and histological recovery.
Topics: Celiac Disease; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Riboflavin; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Gas chromatographic-mass spectrometric analysis of biomarkers related to folate and cobalamin status in human serum after dimercaptopropanesulfonate reduction and heptafluorobutyl chloroformate derivatization.
Topics: Alkanesulfonic Acids; Biomarkers; Fluorocarbons; Folic Acid; Formates; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Methylmalonic Acid; Oxidation-Reduction; Sulfhydryl Compounds; Vitamin B 12 | 2008 |
Serum homocysteine levels and cognitive functioning in euthymic bipolar patients.
Topics: Adult; Age Factors; Bipolar Disorder; Cognition Disorders; Demography; Diagnostic and Statistical Manual of Mental Disorders; Dysthymic Disorder; Female; Folic Acid; Homocysteine; Humans; Male; Neuropsychological Tests; Severity of Illness Index; Sex Factors; Vitamin B 12 | 2009 |
Metformin, B12 and homocysteine levels: the plausible cause or effect?
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Metformin; Venous Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Association between C677T/MTHFR genotype and homocysteine concentration in a Kazakh population.
Topics: Adult; Carbon-Nitrogen Ligases; Creatinine; Ethnicity; Female; Folic Acid; Genotype; Homocysteine; Humans; Japan; Male; Population; Serum Albumin; Vitamin B 12; Vitamin B Complex | 2008 |
High plasma homocysteine is associated with the risk of coronary artery disease independent of methylenetetrahydrofolate reductase 677C-->T genotypes.
Topics: Alleles; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Methionine, folic acid and vitamin B12 in growing-finishing pigs: impact on growth performance and meat quality.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Body Composition; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Male; Meat; Methionine; Nutritional Requirements; Random Allocation; Swine; Vitamin B 12; Vitamin B Complex; Weight Gain | 2008 |
Folate and cobalamin status in relation to breastfeeding and weaning in healthy infants.
Topics: Age Distribution; Analysis of Variance; Breast Feeding; Child, Preschool; Diet Records; Female; Folic Acid; Homocysteine; Humans; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Longitudinal Studies; Male; Methylmalonic Acid; Norway; Nutritional Status; Reference Values; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex; Weaning | 2008 |
Homocysteine, folate and vitamin B(12) in puerperal cerebral venous thrombosis.
Topics: Adolescent; Adult; Confidence Intervals; Female; Folic Acid; Homocysteine; Humans; Intracranial Thrombosis; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Odds Ratio; Prothrombin; Puerperal Disorders; Risk; Risk Assessment; Statistics as Topic; Venous Thrombosis; Vitamin B 12 | 2008 |
Increased folate intake with no changes in serum homocysteine and decreased levels of C-reactive protein in patients with inflammatory bowel diseases.
Topics: Adult; Anthropometry; C-Reactive Protein; Diet; Female; Folic Acid; Homocysteine; Humans; Inflammatory Bowel Diseases; Male; Middle Aged; Nutritional Status; Vitamin B 12; Young Adult | 2009 |
Low serum vitamin B12 is associated with recurrent pregnancy loss in Syrian women.
Topics: Abortion, Habitual; Adult; Female; Homocysteine; Humans; Pregnancy; Syria; Vitamin B 12 | 2008 |
Malondialdehyde, carbonyl proteins and albumin-disulphide as useful oxidative markers in mild cognitive impairment and Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Biomarkers; Case-Control Studies; Cognition Disorders; Disulfides; Female; Folic Acid; Homocysteine; Humans; Male; Malondialdehyde; Middle Aged; Neopterin; Nerve Degeneration; Oxidative Stress; Protein Carbonylation; Serum Albumin; Severity of Illness Index; Vitamin B 12 | 2008 |
Severe methylenetetrahydrofolate reductase (MTHFR) deficiency: a case report of nonclassical homocystinuria.
Topics: Child; Developmental Disabilities; Female; Homocysteine; Homocystinuria; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Severity of Illness Index; Vitamin B 12 | 2008 |
Homocysteine levels and sustained virological response to pegylated-interferon alpha2b plus ribavirin therapy for chronic hepatitis C: a prospective study.
Topics: Antiviral Agents; Folic Acid; Hepacivirus; Hepatitis C, Chronic; Homocysteine; Humans; Interferon alpha-2; Interferon-alpha; Italy; Methylenetetrahydrofolate Dehydrogenase (NADP); Polyethylene Glycols; Polymorphism, Genetic; Prospective Studies; Recombinant Proteins; Ribavirin; RNA, Viral; ROC Curve; Vitamin B 12 | 2009 |
Homocysteine metabolism in the pre-ovulatory follicle during ovarian stimulation.
Topics: Adult; Biomarkers; Chorionic Gonadotropin; Estradiol; Female; Fertilization in Vitro; Folic Acid; Follicular Fluid; Homocysteine; Humans; Ovarian Follicle; Ovulation Induction; Pyridoxal Phosphate; Surveys and Questionnaires; Vitamin B 12 | 2008 |
Serum folate is associated with coronary heart disease independently of homocysteine in Turkish men.
Topics: Adult; Coronary Disease; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Linear Models; Logistic Models; Male; Metabolic Syndrome; Middle Aged; Sex Factors; Turkey; Vitamin B 12 | 2008 |
Methylenetetrahydrofolate reductase 677CT polymorphism and cobalamin, folate, and homocysteine status in Spanish adolescents.
Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Analysis of Variance; Body Mass Index; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Nutrition Assessment; Nutritional Status; Polymorphism, Genetic; Sex Factors; Smoking; Spain; Vitamin B 12; Vitamin B Complex | 2008 |
Vitamin B12 and homocysteine status in asymptomatic Indian toddlers.
Topics: Body Height; Body Weight; Child, Preschool; Comorbidity; Cross-Sectional Studies; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Prevalence; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Neuropathy as a potential complication of levodopa use in Parkinson's disease.
Topics: Analysis of Variance; Antiparkinson Agents; Female; Homocysteine; Humans; Levodopa; Male; Methylmalonic Acid; Parkinson Disease; Peripheral Nervous System Diseases; Retrospective Studies; Vitamin B 12 | 2008 |
Plasma homocysteine thiolactone associated with risk of macrovasculopathy in Chinese patients with type 2 diabetes mellitus.
Topics: Age Factors; Asian People; Body Mass Index; China; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Middle Aged; Risk Factors; Smoking; Time Factors; Vitamin B 12 | 2008 |
Polymorphisms in the CBS gene and homocysteine, folate and vitamin B12 levels: association with polymorphisms in the MTHFR and MTRR genes in Brazilian children.
Topics: Brazil; Child; Child, Preschool; Cystathionine beta-Synthase; Female; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Infant; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Multivariate Analysis; Polymorphism, Genetic; Vitamin B 12 | 2008 |
Cryptogenic stroke and patent foramen ovale: clinical clues to paradoxical embolism.
Topics: Adult; Blood Coagulation Tests; Embolism, Paradoxical; Female; Foramen Ovale, Patent; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Retrospective Studies; Risk Factors; Stroke; Ultrasonography, Doppler, Transcranial; Vitamin B 12 | 2008 |
Relationships between gene polymorphisms of folate-related proteins and vitamins and metabolites in pregnant women and neonates.
Topics: Adult; Brazil; DNA; Embryonic Development; Ethnicity; Female; Folic Acid; Glutamate Carboxypeptidase II; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Pregnancy; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylhomocysteine; S-Adenosylmethionine; Socioeconomic Factors; Vitamin B 12; Vitamin B Complex; Young Adult | 2008 |
Raised homocysteine and low folate and vitamin B-12 concentrations predict cognitive decline in community-dwelling older Japanese adults.
Topics: Age Factors; Aged; Aged, 80 and over; Albumins; Cholesterol; Cognition Disorders; Creatinine; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Japan; Male; Middle Aged; Regression Analysis; Vitamin B 12 | 2008 |
Association between the 2756A> G variant in the gene encoding methionine synthase and myocardial infarction in Tunisian patients.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Male; Middle Aged; Mutation; Myocardial Infarction; Tunisia; Vitamin B 12 | 2008 |
Lack of effect of diet-induced hypomethylation on endothelium-dependent relaxation in rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atherosclerosis; Endothelium, Vascular; Folic Acid Deficiency; Homocysteine; In Vitro Techniques; Liver; Male; Methylation; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; S-Adenosylmethionine; Vasodilation; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Cognitive performance and plasma levels of homocysteine, vitamin B12, folate and lipids in patients with Alzheimer disease.
Topics: Aged; Alzheimer Disease; Cholesterol, HDL; Cholesterol, LDL; Cognition; Cross-Sectional Studies; Databases, Factual; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Psychomotor Performance; Sex Characteristics; Triglycerides; Vitamin B 12 | 2008 |
Higher folate intake is related to lower risk of Alzheimer's disease in the elderly.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Female; Folic Acid; Homocysteine; Humans; Male; Nutrition Assessment; Prospective Studies; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
The relation between serum homocysteine level and eye involvement in Behçet's disease.
Topics: Adolescent; Adult; Behcet Syndrome; Comorbidity; Eye Diseases; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12; Young Adult | 2008 |
Plasma vitamin B12 status and cerebral white-matter lesions.
Topics: Aged; Biomarkers; Brain; Cerebral Infarction; Cerebrovascular Circulation; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Myelin Sheath; Neuropsychological Tests; Population Surveillance; Prevalence; Risk Factors; Severity of Illness Index; Vitamin B 12 | 2009 |
Folate, vitamin B12 and homocysteine status in women of childbearing age: baseline data of folic acid wheat flour fortification in Iran.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Female; Flour; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Iran; Middle Aged; Neural Tube Defects; Nutritional Status; Outcome and Process Assessment, Health Care; Triticum; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2008 |
Vitamin B12 and folate and the risk of anemia in old age: the Leiden 85-Plus Study.
Topics: Aged, 80 and over; Anemia; Cross-Sectional Studies; Erythrocyte Indices; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Hemoglobins; Homocysteine; Humans; Male; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Evaluation of traditional and emerging cardiovascular risk factors in patients with non-arteritic anterior ischemic optic neuropathy: a case-control study.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Case-Control Studies; Dyslipidemias; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Hypertension; Lipoprotein(a); Male; Middle Aged; Optic Neuropathy, Ischemic; Risk Factors; Thrombophilia; Vitamin B 12; Vitamin B 6 | 2009 |
Serum homocysteine, folate, vitamin B12 levels and arterial stiffness in diabetic patients: which of them is really important in atherogenesis?
Topics: Aged; Aged, 80 and over; Atherosclerosis; Biomarkers; Body Mass Index; Creatinine; Diabetes Mellitus; Diabetic Angiopathies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Models, Biological; Overweight; Regression Analysis; Vitamin B 12 | 2009 |
Plasma homocysteine, folate, and vitamin B12 levels in patients with laryngeal cancer.
Topics: Adult; Aged; Aged, 80 and over; Female; Folic Acid; Homocysteine; Humans; Laryngeal Neoplasms; Male; Middle Aged; Vitamin B 12 | 2008 |
Homocyst(e)ine, folate, and vitamin B12 status in a cohort of Welsh young people aged 12-13 years old.
Topics: Adolescent; Age Factors; Body Mass Index; Child; Cohort Studies; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Reference Values; Sex Factors; Vitamin B 12; Waist Circumference; Wales | 2008 |
Hemolysis and hyperhomocysteinemia caused by cobalamin deficiency: three case reports and review of the literature.
Topics: Aged, 80 and over; Anemia, Hemolytic; Erythrocyte Transfusion; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Folate-vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aging; Anemia, Pernicious; Cognition Disorders; Drug Interactions; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Middle Aged; Nutrition Surveys; Nutritional Status; Odds Ratio; Prevalence; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
[Vitamin B substitution. No protection for the heart -- but for the brain!].
Topics: Cohort Studies; Controlled Clinical Trials as Topic; Folic Acid; Homocysteine; Humans; Meta-Analysis as Topic; Myocardial Infarction; Prospective Studies; Retrospective Studies; Risk Factors; Stroke; Time Factors; Vitamin B 12; Vitamin B 6 | 2008 |
The relationship of homocyteine, B12 and folic acid with the bone mineral density of the femur and lumbar spine in Turkish postmenopausal women.
Topics: Absorptiometry, Photon; Adult; Aged; Bone Density; Cross-Sectional Studies; Female; Femur; Folic Acid; Homocysteine; Humans; Lumbar Vertebrae; Middle Aged; Osteoporosis; Postmenopause; Turkey; Vitamin B 12 | 2009 |
Serum vitamin B12, folate, and homocysteine levels and their association with clinical and electrophysiological parameters in multiple sclerosis.
Topics: Adult; Disability Evaluation; Evoked Potentials, Somatosensory; Evoked Potentials, Visual; Female; Folic Acid; Hematocrit; Hemoglobins; Homocysteine; Humans; Immunoglobulin G; Male; Middle Aged; Multiple Sclerosis; Oligoclonal Bands; Retrospective Studies; Vitamin B 12; Young Adult | 2009 |
Association between genetic and environmental factors and the risk of Alzheimer's disease.
Topics: Alzheimer Disease; Apolipoproteins E; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Hypercholesterolemia; Methylenetetrahydrofolate Reductase (NADPH2); Nitric Oxide Synthase Type III; Risk Factors; Vitamin B 12 | 2008 |
Maternal serum homocysteine and risk for neural tube defects in a Texas-Mexico border population.
Topics: Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Mexico; Neural Tube Defects; Pregnancy; Pregnancy Complications; Retrospective Studies; Risk Factors; Texas; Vitamin B 12 | 2009 |
Relationship of homocysteine with other risk factors and outcome of ischemic stroke.
Topics: Adult; Aged; Brain Ischemia; Comorbidity; Diabetes Mellitus; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; India; Male; Middle Aged; Obesity; Risk Factors; Severity of Illness Index; Smoking; Stroke; Tomography, X-Ray Computed; Vitamin B 12 | 2009 |
Dietary sources of vitamin B-12 and their association with plasma vitamin B-12 concentrations in the general population: the Hordaland Homocysteine Study.
Topics: Aged; Aging; Biological Availability; Cross-Sectional Studies; Dairy Products; Diet; Diet Surveys; Female; Homocysteine; Humans; Male; Middle Aged; Norway; Nutritional Requirements; Nutritional Status; Seafood; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2009 |
Effects of metoprolol and diltiazem on plasma homocysteine levels in patients with isolated coronary artery ectasia.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Artery Disease; Dilatation, Pathologic; Diltiazem; Female; Folic Acid; Homocysteine; Humans; Male; Metoprolol; Middle Aged; Treatment Outcome; Vitamin B 12 | 2009 |
Homocysteine, vitamin B12 and folic acid levels in psoriasis patients.
Topics: Adult; Case-Control Studies; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Psoriasis; Vitamin B 12 | 2009 |
Association of genetic variants in Methylenetetrahydrofolate Reductase and Paraoxonase-1 genes with homocysteine, folate and vitamin B12 in coronary artery disease.
Topics: Aged; Aryldialkylphosphatase; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Vitamin B 12 | 2009 |
IVF outcomes are associated with biomarkers of the homocysteine pathway in monofollicular fluid.
Topics: Biomarkers; Female; Fertilization in Vitro; Folic Acid; Follicular Fluid; Homocysteine; Humans; Pregnancy; Pregnancy Rate; Sperm Injections, Intracytoplasmic; Vitamin B 12 | 2009 |
Association between Helicobacter pylori-infection, C-reactive protein and status of B vitamins.
Topics: C-Reactive Protein; Cross-Sectional Studies; Female; Folic Acid; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Risk Factors; Vitamin B 12; Vitamin B 6 | 2008 |
Hyperhomocysteinemia, paraoxonase concentration and cardiovascular complications in Tunisian patients with nondiabetic renal disease.
Topics: Adult; Aryldialkylphosphatase; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multivariate Analysis; Radioimmunoassay; Triglycerides; Tunisia; Vitamin B 12 | 2009 |
Homocysteine-lowering B vitamins do not lower mortality or cardiovascular events.
Topics: Aged; Aortic Valve Stenosis; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk; Survival Analysis; Survival Rate; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Effect of B vitamin supplementation on plasma homocysteine levels in celiac disease.
Topics: Adolescent; Adult; Celiac Disease; Creatinine; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pantothenic Acid; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamin B Complex; Young Adult | 2009 |
Supplemented creatine induces changes in human metabolism of thiocompounds and one- and two-carbon units.
Topics: Adult; Biomarkers; Biotransformation; Creatine; Creatinine; Dietary Proteins; Dietary Supplements; Folic Acid; Homocysteine; Humans; Male; Oxidation-Reduction; Thioglycolates; Time Factors; Vitamin B 12; Young Adult | 2010 |
[Relationship between smoking and homocysteine concentration in ischemic stroke patients].
Topics: Aged; Brain Ischemia; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Sex Factors; Smoking; Stroke; Vitamin B 12 | 2008 |
Urinary methylmalonic acid levels in patients with acute ischemic stroke.
Topics: Aged; Aged, 80 and over; Brain Ischemia; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Stroke; Vitamin B 12 | 2009 |
Deprivation of folate and B12 increases neurodegeneration beyond that accompanying deprivation of either vitamin alone.
Topics: Calcium; Cell Line, Tumor; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Nerve Degeneration; Neuroblastoma; Neurons; Reactive Oxygen Species; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
Hyperhomocysteinaemia and poor vitamin B status in chronic obstructive pulmonary disease.
Topics: Aged; C-Reactive Protein; Case-Control Studies; Cross-Sectional Studies; Female; Folic Acid; Forced Expiratory Volume; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Logistic Models; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Risk Factors; Thrombosis; Vital Capacity; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2009 |
High milk consumers have an increased risk of folate receptor blocking autoantibody production but this does not affect folate status in Spanish men and women.
Topics: Adolescent; Adult; Aged; Animals; Autoantibodies; Carrier Proteins; Cross-Sectional Studies; Diet; Diet Records; Erythrocytes; Female; Folate Receptors, GPI-Anchored; Folic Acid; Homocysteine; Humans; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Milk; Polymorphism, Genetic; Receptors, Cell Surface; Spain; Vitamin B 12 | 2009 |
Evidence that folic acid deficiency is a major determinant of hyperhomocysteinemia in Parkinson's disease.
Topics: Analysis of Variance; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Matched-Pair Analysis; Middle Aged; Nerve Degeneration; Parkinson Disease; Reference Values; Statistics, Nonparametric; Vitamin B 12 | 2009 |
Plasma folate and total homocysteine levels are associated with the risk of myocardial infarction, independently of each other and of renal function.
Topics: Adult; Aged; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Health Surveys; Homocysteine; Humans; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Prospective Studies; Riboflavin; Risk; Sex Distribution; Sweden; Vitamin B 12; Vitamin B 6 | 2009 |
Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations.
Topics: Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Female; Folic Acid; Fucosyltransferases; Galactoside 2-alpha-L-fucosyltransferase; Genome-Wide Association Study; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Proteins; Polymorphism, Single Nucleotide; Receptors, Cell Surface; Transcobalamins; Vitamin B 12; Vitamin B 6 | 2009 |
Mechanisms of thrombogenesis in atrial fibrillation.
Topics: Atrial Fibrillation; Blood Coagulation Factors; Homocysteine; Humans; Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
Variations in folate pathway genes are associated with unexplained female infertility.
Topics: Adult; Carrier Proteins; Cross-Sectional Studies; Cystathionine gamma-Lyase; Female; Folate Receptor 1; Folate Receptors, GPI-Anchored; Folic Acid; Genetic Association Studies; Genetic Variation; Homocysteine; Humans; Infertility, Female; Membrane Transport Proteins; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Receptors, Cell Surface; Reduced Folate Carrier Protein; Signal Transduction; Transcobalamins; Vitamin B 12 | 2010 |
Vitamin B-12 and homocysteine status among vegetarians: a global perspective.
Topics: Anemia, Pernicious; Atherosclerosis; Cardiovascular Diseases; Diet, Vegetarian; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
Vitamin B(12) deficiency stimulates osteoclastogenesis via increased homocysteine and methylmalonic acid.
Topics: Animals; Bone and Bones; Bone Density; Bone Remodeling; Cell Differentiation; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Homocysteine; Humans; Male; Methylmalonic Acid; Mice; Mice, Inbred C57BL; Osteoclasts; Osteoporosis; Up-Regulation; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
Association between cholesterols, homocysteine and silent brain infarcts.
Topics: Adult; Aged; Aged, 80 and over; Blood Chemical Analysis; Brain Infarction; Cardiovascular Diseases; Cholesterol; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Lipoproteins, LDL; Magnetic Resonance Imaging; Male; Middle Aged; Risk Factors; Sex Factors; Vitamin B 12; Young Adult | 2009 |
[Plasma homocysteine concentration in patients with ischaemic stroke caused by large or small vessel disease].
Topics: Brain Ischemia; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12 | 2009 |
Plasma homocysteine and cerebrospinal fluid neurodegeneration biomarkers in mild cognitive impairment and dementia.
Topics: Aged; Amyloid beta-Peptides; Biomarkers; Chromatography, High Pressure Liquid; Creatinine; Dementia; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Germany; Homocysteine; Humans; Immunoassay; Linear Models; Male; Middle Aged; Nephelometry and Turbidimetry; Nerve Degeneration; Peptide Fragments; tau Proteins; Vitamin B 12 | 2009 |
A novel role for vitamin B(12): Cobalamins are intracellular antioxidants in vitro.
Topics: Acetylcysteine; Antioxidants; Cell Line; Cell Survival; Cysteine; Glutathione; Homocysteine; Humans; Hydrogen Peroxide; Oxidative Stress; Reactive Oxygen Species; Vitamin B 12; Vitamin B Complex | 2009 |
Association of maternal serum CRP, IL-6, TNF-alpha, homocysteine, folic acid and vitamin B12 levels with the severity of preeclampsia and fetal birth weight.
Topics: Adult; Biomarkers; Birth Weight; C-Reactive Protein; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Infant, Low Birth Weight; Infant, Newborn; Interleukin-6; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Tumor Necrosis Factor-alpha; Vitamin B 12; Young Adult | 2009 |
Effects of a low-protein diet on plasma amino acid and homocysteine levels and oxidative status in rats.
Topics: Amino Acids; Animals; Blood Proteins; Body Weight; Creatinine; Diet; Diet, Protein-Restricted; Folic Acid; Glutathione; Homocysteine; Lipid Peroxidation; Liver; Male; Organ Size; Oxidative Stress; Rats; Rats, Wistar; Regression Analysis; Vitamin B 12 | 2009 |
Homocysteine concentrations in follicular fluid are associated with poor oocyte and embryo qualities in polycystic ovary syndrome patients undergoing assisted reproduction.
Topics: Adult; Embryo, Mammalian; Estradiol; Female; Folic Acid; Follicle Stimulating Hormone; Follicular Fluid; Homocysteine; Humans; Infertility, Female; Malondialdehyde; Oocytes; Ovulation Induction; Polycystic Ovary Syndrome; Reproductive Techniques, Assisted; Vitamin B 12 | 2009 |
[Recurrent ischemic stroke revealing Biermer's disease].
Topics: Anemia, Pernicious; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Middle Aged; Recurrence; Vitamin B 12 | 2009 |
Homocysteine and cognitive impairment in Parkinson's disease: a biochemical, neuroimaging, and genetic study.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Aged, 80 and over; Brain; Carbon-Nitrogen Ligases; Case-Control Studies; Cognition Disorders; Cystathionine beta-Synthase; Depression; Female; Folic Acid; Homocysteine; Humans; Immunoassay; Logistic Models; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Parkinson Disease; Polymorphism, Genetic; Severity of Illness Index; Vitamin B 12; Vitamin B 6 | 2009 |
Telomere length in peripheral blood mononuclear cells is associated with folate status in men.
Topics: beta-Globins; Cellular Senescence; DNA; Folic Acid; Genotype; Homocysteine; Humans; Leukocytes, Mononuclear; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Single Nucleotide; RNA; Telomere; Vitamin B 12 | 2009 |
Folate, Cobalamin, Cysteine, Homocysteine, and Arsenic Metabolism among Children in Bangladesh.
Topics: Arsenic; Child; Cysteine; Environmental Exposure; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Sex Factors; Vitamin B 12; Water Pollutants, Radioactive | 2009 |
Blood levels of homocysteine, cysteine, glutathione, folic acid, and vitamin B12 in the acute phase of atherothrombotic stroke.
Topics: Acute Disease; Aged; Aged, 80 and over; Brain Ischemia; Cysteine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Male; Middle Aged; Risk Factors; Stroke; Vitamin B 12; Vitamins | 2009 |
Folate, vitamin B12, homocysteine, and depressive symptoms in a population sample of older Chinese adults.
Topics: Aged; Cross-Sectional Studies; Depression; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Risk Factors; Singapore; Vitamin B 12 | 2009 |
Association between vitamin B12-containing supplement consumption and prevalence of biochemically defined B12 deficiency in adults in NHANES III (third national health and nutrition examination survey).
Topics: Adolescent; Adult; Age Factors; Cross-Sectional Studies; Dietary Supplements; Female; Food, Fortified; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Nutrition Surveys; Prevalence; United States; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2010 |
Role of thrombotic risk factors in end-stage renal disease.
Topics: 3' Untranslated Regions; Adult; Alleles; Amino Acid Substitution; Factor V; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Point Mutation; Prothrombin; Risk Factors; Thrombophilia; Vitamin B 12; Young Adult | 2010 |
Association between asymmetric dimethylarginine and neopterin in patients with and without angiographic coronary artery disease.
Topics: Arginine; Chromatography, High Pressure Liquid; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Middle Aged; Neopterin; Risk Factors; Vitamin B 12; Vitamin B 6 | 2009 |
Plasma vitamins, amino acids, and renal function in postexercise hyperhomocysteinemia.
Topics: Adolescent; Amino Acids; Creatinine; Exercise; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Male; Physical Exertion; Vitamin B 12; Young Adult | 2009 |
Homocysteine levels in patients with Behçet's disease and patients with recurrent aphthous stomatitis.
Topics: Adolescent; Adult; Behcet Syndrome; Biomarkers; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Recurrence; Stomatitis, Aphthous; Vitamin B 12; Young Adult | 2009 |
Association between plasma homocysteine levels and mortality in elderly patients with mental illness.
Topics: Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Kaplan-Meier Estimate; Kidney Function Tests; Male; Mental Disorders; Middle Aged; Proportional Hazards Models; Regression Analysis; Survival Analysis; Vascular Diseases; Vitamin B 12 | 2009 |
An investigation of vitamin B12 deficiency in elderly inpatients in neurology department.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Anemia, Megaloblastic; Electrophysiology; Female; Folic Acid; Geriatric Assessment; Homocysteine; Humans; Male; Middle Aged; Neurologic Examination; Neuropsychological Tests; Nutritional Status; Prevalence; Retrospective Studies; Risk Factors; Sex Factors; Statistics as Topic; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
Association between MTHFR 677C-T polymorphism and alcohol dependence according to Lesch and Babor typology.
Topics: Adult; Alcoholism; Depressive Disorder; Female; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12 | 2009 |
A New DiaSys colorimetric assay for plasma homocysteine: application in diabetic patients.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; C-Reactive Protein; Chromatography, High Pressure Liquid; Colorimetry; Diabetes Mellitus; Female; Folic Acid; Glomerular Filtration Rate; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Reproducibility of Results; Vitamin B 12 | 2009 |
Folate content in different strawberry genotypes and folate status in healthy subjects after strawberry consumption.
Topics: Adult; Biomarkers; Eating; Female; Folic Acid; Fragaria; Genotype; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Pilot Projects; Reference Values; Vitamin B 12; Young Adult | 2008 |
Is asymmetric dimethylarginine responsible for the vascular events in patients under antiepileptic drug treatment?
Topics: Adult; Anticonvulsants; Arginine; Arterial Occlusive Diseases; Carbamazepine; Drug Monitoring; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Statistics, Nonparametric; Valproic Acid; Vitamin B 12 | 2009 |
Rate of T alleles and TT genotype at MTHFR 677C->T locus or C alleles and CC genotype at MTHFR 1298A->C locus among healthy subjects in Turkey: impact on homocysteine and folic acid status and reference intervals.
Topics: Adolescent; Adult; Alleles; Female; Folic Acid; Genotype; Health Status; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Turkey; Vitamin B 12; Young Adult | 2009 |
Increases in plasma holotranscobalamin can be used to assess vitamin B-12 absorption in individuals with low plasma vitamin B-12.
Topics: Adult; Body Height; Body Weight; Cardiovascular Diseases; Child; Diabetes Mellitus, Type 2; Fathers; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Intestinal Absorption; Male; Maternal Nutritional Physiological Phenomena; Mother-Child Relations; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
The associations between blood levels of homocysteine, folate, vitamin B12, and retinal vascular caliber.
Topics: Aged; Aging; Arterioles; Blood Pressure; Body Mass Index; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Photography; Retinal Artery; Retinal Vein; Sex Factors; Smoking; Venules; Vitamin B 12 | 2009 |
The association between high plasma homocysteine levels and lower bone mineral density in Slovak women: the impact of vegetarian diet.
Topics: Adult; Age Distribution; Aged; Albumins; Blood Glucose; Bone Density; Calcium; Causality; Cohort Studies; Creatinine; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Phosphorus; Risk Factors; Slovakia; Vitamin B 12; Young Adult | 2010 |
Body mass index is an important determinant of methylation biomarkers in women of reproductive ages.
Topics: Adult; Biomarkers; Body Mass Index; Female; Fertility; Folic Acid; Homocysteine; Humans; Life Style; Methylation; Middle Aged; Multivariate Analysis; Netherlands; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2009 |
Folate status of Ghanaian populations in London and Accra.
Topics: Adult; Black People; Educational Status; Erythrocytes; Fasting; Female; Folic Acid; Ghana; Guinea; Homocysteine; Humans; Incidence; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Polymorphism, Single Nucleotide; Smoking; Stroke; Urban Population; Vitamin B 12 | 2010 |
Folic acid source, usual intake, and folate and vitamin B-12 status in US adults: National Health and Nutrition Examination Survey (NHANES) 2003-2006.
Topics: Adult; Aged; Demography; Diet; Dietary Supplements; Energy Intake; Ethnicity; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Interviews as Topic; Male; Memory; Middle Aged; Nutrition Surveys; Racial Groups; United States; Vitamin B 12; Young Adult | 2010 |
Folic acid, vitamin B12, and homocysteine levels during fasting and after methionine load in patients with Type 1 diabetes mellitus.
Topics: Adolescent; Adult; Aging; Blood Glucose; Case-Control Studies; Child; Diabetes Mellitus, Type 1; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Sex Characteristics; Vitamin B 12; Young Adult | 2010 |
Subclinical vitamin B12 deficiency in pregnant women attending an antenatal clinic in Nigeria.
Topics: Adult; Ambulatory Care Facilities; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Methylmalonic Acid; Nigeria; Pregnancy; Pregnancy Complications; Prenatal Care; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2009 |
Hyperhomocysteinaemia, low folate concentrations and methylene tetrahydrofolate reductase C677T mutation in acute mesenteric venous thrombosis.
Topics: Acute Disease; Adult; Aged; Asian People; Biomarkers; Case-Control Studies; Chi-Square Distribution; China; Chromatography, High Pressure Liquid; Down-Regulation; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Immunoassay; Male; Mesenteric Vascular Occlusion; Mesenteric Veins; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Odds Ratio; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Risk Assessment; Risk Factors; Venous Thrombosis; Vitamin B 12; Young Adult | 2010 |
Association of metformin, elevated homocysteine, and methylmalonic acid levels and clinically worsened diabetic peripheral neuropathy.
Topics: Aged; Case-Control Studies; Chromatography, High Pressure Liquid; Diabetic Neuropathies; Electrophysiology; Female; Homocysteine; Humans; Hypoglycemic Agents; Immunoassay; Male; Mass Spectrometry; Metformin; Methylmalonic Acid; Middle Aged; Peripheral Nervous System Diseases; Prospective Studies; Vitamin B 12 | 2010 |
Associations of plasma homocysteine level with brachial-ankle pulse wave velocity, LDL atherogenicity, and inflammation profile in healthy men.
Topics: Adult; Aged; Ankle; Ankle Brachial Index; Asian People; Atherosclerosis; Blood Flow Velocity; Blood Glucose; Blood Pressure; Brachial Artery; C-Reactive Protein; Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Lipoproteins, LDL; Male; Middle Aged; Tumor Necrosis Factor-alpha; Vascular Resistance; Vitamin B 12 | 2011 |
Holotranscobalamin as an indicator of vitamin B12 deficiency in gastrectomized patients.
Topics: Adult; Aged; Aged, 80 and over; Erythrocyte Indices; Female; Gastrectomy; Homocysteine; Humans; Male; Middle Aged; Reference Values; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
Observational study on markers of cardiovascular risk in renal patient: conventional hemodialysis vs. haemofiltration online.
Topics: Biomarkers; Cardiovascular Diseases; Chi-Square Distribution; Cross-Sectional Studies; Female; Folic Acid; Hemodiafiltration; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Obesity; Online Systems; Renal Dialysis; Risk Assessment; Risk Factors; Treatment Outcome; Vitamin B 12 | 2009 |
Serum folate is a reliable indicator of hyperhomocysteinemia and borderline hyperhomocysteinemia in young adults.
Topics: Adolescent; Adult; Area Under Curve; Biomarkers; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Pyridoxal Phosphate; Reference Values; Risk Factors; Severity of Illness Index; Taiwan; Vitamin B 12; Young Adult | 2009 |
Effects of metformin with or without supplementation with folate on homocysteine levels and vascular endothelium of women with polycystic ovary syndrome.
Topics: Adult; Body Mass Index; Brachial Artery; Double-Blind Method; Endothelin-1; Endothelium, Vascular; Exercise; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Leisure Activities; Metformin; Placebos; Polycystic Ovary Syndrome; Tunica Intima; Tunica Media; Vasodilation; Vitamin B 12; Waist-Hip Ratio | 2010 |
The maternal homocysteine pathway is influenced by riboflavin intake and MTHFR polymorphisms without affecting the risk of orofacial clefts in the offspring.
Topics: Biomarkers; Case-Control Studies; Cleft Lip; Cleft Palate; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Linear Models; Logistic Models; Methylenetetrahydrofolate Reductase (NADPH2); Nutrigenomics; Odds Ratio; Polymorphism, Genetic; Riboflavin; Risk Factors; Surveys and Questionnaires; Vitamin B 12 | 2010 |
Relationship between bone mineral density, bone turnover markers and homocysteine, folate and vitamin B12 levels in postmenopausal women.
Topics: Alkaline Phosphatase; Biomarkers; Bone Density; Collagen Type I; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Peptides; Postmenopause; Vitamin B 12 | 2010 |
Methyl donor deficiency affects fetal programming of gastric ghrelin cell organization and function in the rat.
Topics: Animals; Body Weight; Cell Lineage; Choline; Deficiency Diseases; Enteroendocrine Cells; Female; Fetal Development; Folic Acid; Gastric Mucosa; Ghrelin; Growth Hormone; Homocysteine; Immunohistochemistry; Pregnancy; Rats; Rats, Wistar; Vitamin B 12; Weaning | 2010 |
Determination of serum holotranscobalamin concentrations with the AxSYM active B(12) assay: cut-off point evaluation in the clinical laboratory.
Topics: Aged; Biomarkers; Blood Chemical Analysis; Female; Folic Acid; Homocysteine; Humans; Immunoenzyme Techniques; Male; Middle Aged; Sensitivity and Specificity; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2010 |
Reduced folic acid, vitamin B12 and docosahexaenoic acid and increased homocysteine and cortisol in never-medicated schizophrenia patients: implications for altered one-carbon metabolism.
Topics: Adolescent; Adult; Case-Control Studies; Docosahexaenoic Acids; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hydrocortisone; Male; Psychiatric Status Rating Scales; Schizophrenia; Vitamin B 12; Young Adult | 2010 |
One-carbon metabolism and CpG island methylator phenotype status in incident colorectal cancer: a nested case-referent study.
Topics: Aged; Carbon; Case-Control Studies; Colorectal Neoplasms; CpG Islands; DNA Methylation; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Incidence; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Risk Factors; Sweden; Vitamin B 12 | 2010 |
Obesity and insulin resistance associated with lower plasma vitamin B12 in PCOS.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Insulin Resistance; Obesity; Polycystic Ovary Syndrome; Vitamin B 12 | 2009 |
Hyperhomocysteinemia recurrence in levodopa-treated Parkinson's disease patients.
Topics: Aged; Cross-Sectional Studies; Dopamine Agents; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Parkinson Disease; Prospective Studies; Secondary Prevention; Treatment Outcome; Vitamin B 12 | 2010 |
Metabolic signs of vitamin B(12) deficiency in humans: computational model and its implications for diagnostics.
Topics: Computer Simulation; Homocysteine; Humans; Methylmalonic Acid; Probability; ROC Curve; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2010 |
677C>T and 1298A>C polymorphisms of methylenetetrahydropholate reductase gene and biochemical parameters in Turkish population with spina bifida occulta.
Topics: Adenine; Case-Control Studies; Cytosine; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Reference Values; Spina Bifida Occulta; Thymine; Turkey; Vitamin B 12 | 2010 |
Daily intake of 4 to 7 microg dietary vitamin B-12 is associated with steady concentrations of vitamin B-12-related biomarkers in a healthy young population.
Topics: Adolescent; Adult; Antibodies, Bacterial; Autoantibodies; Biomarkers; Diet; Dose-Response Relationship, Drug; Female; Helicobacter pylori; Homocysteine; Humans; Intrinsic Factor; Male; Methylmalonic Acid; Middle Aged; Nutrition Policy; Nutritional Requirements; Nutritional Status; Reference Values; Vitamin B 12; Vitamin B Complex; Young Adult | 2010 |
Validity of brief food frequency questionnaire for estimation of dietary intakes of folate, vitamins B6 and B12, and their associations with plasma homocysteine concentrations.
Topics: Adult; Diet; Diet Surveys; Female; Folic Acid; Homocysteine; Humans; Japan; Male; Middle Aged; Nutrition Assessment; Reproducibility of Results; Statistics, Nonparametric; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2010 |
Air pollution and homocysteine: more evidence that oxidative stress-related genes modify effects of particulate air pollution.
Topics: Aged; Aged, 80 and over; Air Pollution; Cohort Studies; Environmental Exposure; Genotype; Heart Rate; Homocysteine; Humans; Male; Middle Aged; Oxidative Stress; Particulate Matter; Polymorphism, Single Nucleotide; Soot; Vitamin B 12; Vitamin B 6 | 2010 |
A novel mutation in LMBRD1 causes the cblF defect of vitamin B(12) metabolism in a Turkish patient.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alleles; Female; Fibroblasts; Homocysteine; Humans; Lysosomes; Male; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Mutation; Nucleocytoplasmic Transport Proteins; Turkey; Vitamin B 12 | 2010 |
Homocysteine and pro-inflammatory cytokine concentrations in acute heart disease.
Topics: Cardiovascular Diseases; Case-Control Studies; Demography; Folic Acid; Homocysteine; Humans; Inflammation; Interleukin-2; Interleukin-6; Middle Aged; ROC Curve; Vitamin B 12 | 2010 |
The TCN2 776CNG polymorphism correlates with vitamin B(12) cellular delivery in healthy adult populations.
Topics: Adult; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Middle Aged; Phenotype; Polymorphism, Genetic; Transcobalamins; Vitamin B 12 | 2010 |
Basolateral efflux mediated by multidrug resistance-associated protein 3 (Mrp3/Abcc3) facilitates intestinal absorption of folates in mouse.
Topics: Animals; Folic Acid; Gene Deletion; Homocysteine; Intestinal Absorption; Leucovorin; Male; Mice; Multidrug Resistance-Associated Proteins; Tetrahydrofolates; Vitamin B 12 | 2010 |
Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects.
Topics: Adult; Base Sequence; DNA Methylation; Educational Status; Embryonic Development; Female; Genome, Human; Homocysteine; Humans; Immunoassay; Long Interspersed Nucleotide Elements; Male; Malnutrition; Molecular Sequence Data; Neural Tube Defects; Open Reading Frames; Parity; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12; Young Adult | 2010 |
Plasma homocysteine levels in patients with normal tension glaucoma.
Topics: Aged; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Fluorescence Polarization Immunoassay; Folic Acid; Homocysteine; Humans; Immunoassay; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Prospective Studies; Vitamin B 12; Vitamin B 6 | 2010 |
Magnetic resonance angiography findings in patients with ischemic stroke from North India.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Biomarkers; Blood Glucose; Body Mass Index; Brain Ischemia; Carotid Artery, External; Carotid Artery, Internal; Diabetes Mellitus; Feeding Behavior; Female; Folic Acid; Homocysteine; Humans; Hypertension; India; Lipids; Magnetic Resonance Angiography; Male; Middle Aged; Racial Groups; Risk Factors; Socioeconomic Factors; Stroke; Vitamin B 12; Young Adult | 2010 |
Plasma homocysteine and cysteine and risk of breast cancer in women.
Topics: Breast Neoplasms; Case-Control Studies; Cysteine; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Prospective Studies; Pyridoxal Phosphate; Vitamin B 12 | 2010 |
[Plasma levels of folate and vitamin B(12) in patients with chronic liver disease].
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Diagnosis, Differential; Erythrocyte Indices; Female; Folic Acid; Folic Acid Deficiency; gamma-Glutamyltransferase; Homocysteine; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Liver Diseases, Alcoholic; Liver Failure; Liver Function Tests; Male; Middle Aged; Prognosis; Prospective Studies; Vitamin B 12; Young Adult | 2010 |
Fasting and post-methionine homocysteine levels in Alzheimers disease and vascular dementia.
Topics: Aged; Alzheimer Disease; Case-Control Studies; Cohort Studies; Dementia, Vascular; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Statistics, Nonparametric; Vitamin B 12 | 2009 |
Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older Hispanics.
Topics: Aged; Aging; Analysis of Variance; California; Female; Genotype; Health Surveys; Hispanic or Latino; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylmalonic Acid; Middle Aged; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12; Vitamin B Complex; White People | 2010 |
Total homocysteine in patients with angiographic coronary artery disease correlates with inflammation markers.
Topics: Aged; Biomarkers; C-Reactive Protein; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Creatinine; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Inflammation Mediators; Male; Middle Aged; Neopterin; Vitamin B 12 | 2010 |
Are dietary choline and betaine intakes determinants of total homocysteine concentration?
Topics: Betaine; Cardiovascular Diseases; Choline; Cognition Disorders; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Vitamin B 12; Vitamin B 6 | 2010 |
MTHFR gene polymorphism and its relationship with plasma homocysteine and folate in a North Indian population.
Topics: Adolescent; Adult; Age Factors; Aged; DNA Mutational Analysis; Feeding Behavior; Female; Folic Acid; Genetics, Population; Homocysteine; Humans; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Young Adult | 2010 |
Prevalence of hyperhomocysteinaemia in a Chinese elderly population.
Topics: Aged; Alcohol Drinking; China; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Prevalence; Sex Factors; Surveys and Questionnaires; Vitamin B 12 | 2010 |
Hyperhomocysteinemia is not associated with reduced bone quality in humans with hip osteoarthritis.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Bone Density; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Osteoarthritis, Hip; Vitamin B 12; Vitamin B 6 | 2010 |
Effect of highly active antiretroviral therapy on homocysteine plasma concentrations in HIV-1-infected patients.
Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Erythrocytes; Female; Folic Acid; HIV Infections; HIV-1; Homocysteine; Humans; Male; Metabolic Diseases; Middle Aged; Plasma; Prospective Studies; Vitamin B 12; Vitamin B 6 | 2010 |
Major determinants of serum homocysteine concentrations in a Korean population.
Topics: Adult; Aged; Aged, 80 and over; Asian People; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2010 |
Plasma homocysteine--a marker of vascular disease in elderly patients with mental illness.
Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Female; Folic Acid; Homocysteine; Humans; Kidney; Logistic Models; Male; Mental Disorders; Middle Aged; Predictive Value of Tests; Vascular Diseases; Vitamin B 12 | 2010 |
[Vitamin B12 concentration in the blood of alcoholics].
Topics: Adult; Aged; Alcoholism; Biomarkers; Folic Acid; Homocysteine; Humans; Liver Diseases, Alcoholic; Male; Middle Aged; Reference Values; Vitamin B 12 | 2010 |
A prospective study of one-carbon metabolism biomarkers and risk of renal cell carcinoma.
Topics: Biomarkers; Carbon; Carcinoma, Renal Cell; Case-Control Studies; Chromatography, High Pressure Liquid; Cysteine; Folic Acid; Homocysteine; Humans; Kidney Neoplasms; Logistic Models; Male; Middle Aged; Prospective Studies; Riboflavin; Risk Assessment; Risk Factors; Vitamin B 12; Vitamin B 6 | 2010 |
Deficiencies of folate and vitamin B12 do not affect fracture healing in mice.
Topics: Animals; Biomechanical Phenomena; Body Weight; Bony Callus; Femoral Fractures; Folic Acid; Folic Acid Deficiency; Fracture Healing; Homocysteine; Mice; Radiography; Vitamin B 12; Vitamin B 12 Deficiency | 2010 |
Dietary intake of vitamins B6, B12 and folate in relation to homocysteine serum concentration in the adult Polish population - WOBASZ Project.
Topics: Adolescent; Adult; Aged; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Nutrition Policy; Poland; Population Surveillance; Vitamin B 12; Vitamin B 6; Young Adult | 2010 |
Vitamin B12 deficiency in African American and white octogenarians and centenarians in Georgia.
Topics: Age Factors; Aged, 80 and over; Aging; Black or African American; Erythrocytes; Female; Folic Acid; Georgia; Homocysteine; Humans; Male; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency; White People | 2010 |
Homocysteine, vitamin B12 and folate levels in Iranian patients with ischemic stroke.
Topics: Aged; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Iran; Male; Middle Aged; Stroke; Vitamin B 12 | 2010 |
Relationship between the Levels of Holotranscobalamin and Vitamin B12.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Biomarkers; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2010 |
Levels of circulating homocysteine, vitamin B6, vitamin B12, and folate in different types of open-angle glaucoma.
Topics: Aged; Chromatography, High Pressure Liquid; Female; Folic Acid; Glaucoma, Open-Angle; Homocysteine; Humans; Male; Middle Aged; Prospective Studies; Vitamin B 12; Vitamin B 6 | 2010 |
Plasma homocysteine in schizophrenia: determinants and clinical correlations in Tunisian patients free from antipsychotics.
Topics: Adult; Dementia; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Psychiatric Status Rating Scales; Psychometrics; Retrospective Studies; Schizophrenia; Statistics as Topic; Tunisia; Vitamin B 12 | 2010 |
Increased levels of homocysteine in patients with ulcerative colitis.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Chi-Square Distribution; Colitis, Ulcerative; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Risk Assessment; Risk Factors; Thromboembolism; Up-Regulation; Vitamin B 12; Young Adult | 2010 |
Homocysteine in small-for-gestational age and appropriate-for-gestational age preterm neonates from mothers receiving folic acid supplementation.
Topics: Adult; Birth Weight; Female; Fetal Blood; Fetal Growth Retardation; Folic Acid; Folic Acid Deficiency; Gestational Age; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Mothers; Predictive Value of Tests; Pregnancy; Premature Birth; Vitamin B 12 | 2010 |
[Homocysteine as a residual risk factor in cardiovascular diseases].
Topics: Biomarkers; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Risk Factors; Vitamin B 12; Vitamin B 6 | 2010 |
Contribution of dietary intakes of antioxidants to homocysteine-induced low density lipoprotein (LDL) oxidation in atherosclerotic patients.
Topics: Adult; Aged; Antioxidants; Atherosclerosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Risk Factors; Vitamin B 12; Vitamin B Complex | 2010 |
Positive newborn screen for methylmalonic aciduria identifies the first mutation in TCblR/CD320, the gene for cellular uptake of transcobalamin-bound vitamin B(12).
Topics: Amino Acid Sequence; Antigens, CD; Base Sequence; Cells, Cultured; DNA Mutational Analysis; Female; Fibroblasts; Homocysteine; Humans; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methylmalonic Acid; Molecular Sequence Data; Mutation; Neonatal Screening; Pregnancy; Receptors, Cell Surface; Transcobalamins; Vitamin B 12 | 2010 |
Effect of lipopenic and hypotensive treatment on homocysteine levels in type 2 diabetics.
Topics: Aged; Antihypertensive Agents; Biomarkers; Case-Control Studies; Chi-Square Distribution; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Male; Middle Aged; Odds Ratio; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Triglycerides; Vitamin B 12 | 2010 |
Determinants of homocysteine levels in Ivorian rural population.
Topics: Adult; Aged; C-Reactive Protein; Cholesterol; Cote d'Ivoire; Creatinine; Feeding Behavior; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Male; Middle Aged; Rural Population; Serum Albumin; Statistics, Nonparametric; Triglycerides; Vitamin B 12; Young Adult | 2009 |
Homocysteine status and cardiovascular risk factors in patients with psoriasis: a case-control study.
Topics: Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Psoriasis; Risk Factors; Severity of Illness Index; Vitamin B 12 | 2011 |
Unmetabolized serum folic acid and its relation to folic acid intake from diet and supplements in a nationally representative sample of adults aged > or =60 y in the United States.
Topics: Aged; Diet; Dietary Supplements; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Nutrition Surveys; Tetrahydrofolates; United States; Vitamin B 12 | 2010 |
Serum homocysteine and folate concentrations are associated with prevalent age-related hearing loss.
Topics: Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Female; Folic Acid; Health Surveys; Hearing Loss; Homocysteine; Humans; Male; Multivariate Analysis; Odds Ratio; Vitamin B 12 | 2010 |
Vitamin B12-responsive severe leukoencephalopathy and autonomic dysfunction in a patient with "normal" serum B12 levels.
Topics: Autoantibodies; Autonomic Nervous System Diseases; Brain; Cognition Disorders; Depressive Disorder; Drug Therapy, Combination; Female; Homocysteine; Humans; Intrinsic Factor; Leukoencephalopathies; Magnetic Resonance Imaging; Mental Status Schedule; Methylmalonic Acid; Middle Aged; Neurologic Examination; Psychometrics; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D | 2010 |
C677T polymorphism of the methylenetetrahydrofolate reductase gene does not affect folic acid, vitamin B12, and homocysteine serum levels in Turkish children with neural tube defects.
Topics: Adult; Alleles; Child; Child, Preschool; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Polymorphism, Genetic; Turkey; Vitamin B 12 | 2010 |
Genetic polymorphism of methylenetetrahydrofolate reductase G1793A, hyperhomocysteinemia, and folate deficiency correlate with ulcerative colitis in central China.
Topics: Adult; Alleles; China; Colitis, Ulcerative; DNA; Female; Folic Acid; Folic Acid Deficiency; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Immunoenzyme Techniques; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Polymorphism, Genetic; Prevalence; Vitamin B 12 | 2010 |
Vitamin B-12 status is not associated with plasma homocysteine in parents and their preschool children: lacto-ovo, lacto, and ovo vegetarians and omnivores.
Topics: Adult; Child; Child, Preschool; Diet; Diet Records; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Male; Nutritional Status; Vitamin B 12 | 2010 |
The relationship between plasma homocysteine levels and bone mineral density in post-menopausal women.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Body Mass Index; Bone Density; Chi-Square Distribution; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Italy; Linear Models; Menopause; Middle Aged; Osteoporosis; Vitamin B 12 | 2010 |
Elevated levels of methylmalonate and homocysteine in Parkinson's disease, progressive supranuclear palsy and amyotrophic lateral sclerosis.
Topics: Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Matched-Pair Analysis; Methylmalonic Acid; Middle Aged; Parkinson Disease; Reference Values; Supranuclear Palsy, Progressive; Vitamin B 12 | 2010 |
Associations between holotranscobalamin, vitamin B12, homocysteine and depressive symptoms in community-dwelling elders.
Topics: Aged; Aged, 80 and over; Biomarkers; Cohort Studies; Depressive Disorder; Female; Homocysteine; Humans; Male; Northern Ireland; Personal Satisfaction; Prospective Studies; Transcobalamins; Urban Population; Vitamin B 12 | 2011 |
Serum vitamin B12 and homocysteine levels in pregnant women with neural tube defect.
Topics: Adult; Case-Control Studies; Female; Fetal Diseases; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Neural Tube Defects; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2010 |
Comparisons of plasma/serum micronutrients between Okinawan and Oregonian elders: a pilot study.
Topics: Aged, 80 and over; alpha-Tocopherol; Cognition; Cross-Cultural Comparison; Female; Folic Acid; gamma-Tocopherol; Homocysteine; Humans; Japan; Male; Micronutrients; Oregon; Pilot Projects; Potassium; Sodium; Vitamin B 12 | 2010 |
Association between adherence to folic acid supplements and serum folate, and plasma homocysteine among hemodialysis patients.
Topics: Administration, Oral; Adult; Aged; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multicenter Studies as Topic; Patient Compliance; Randomized Controlled Trials as Topic; Renal Dialysis; Vitamin B 12; Vitamin B 6 | 2011 |
Oxidative stress is increased in primary and post-polycythemia vera myelofibrosis.
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Chronic Disease; Female; Folic Acid; Homocysteine; Humans; Janus Kinase 2; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidative Stress; Polycythemia Vera; Polymorphism, Single Nucleotide; Primary Myelofibrosis; Reactive Oxygen Species; Transcobalamins; Vitamin B 12 | 2010 |
Polymorphism of MTHFR C677T, serum vitamin levels and cognition in subjects with hyperhomocysteinemia in China.
Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognition Disorders; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6; Vitamins | 2010 |
Relation of plasma total homocysteine, folate and vitamin B12 levels to bone mineral density in Moroccan healthy postmenopausal women.
Topics: Absorptiometry, Photon; Age Factors; Aged; Body Mass Index; Bone Density; Bone Diseases, Metabolic; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Lumbar Vertebrae; Middle Aged; Morocco; Osteoporosis, Postmenopausal; Parathyroid Hormone; Postmenopause; Retrospective Studies; Risk Factors; Vitamin B 12 | 2012 |
Seminal plasma homocysteine, folate and cobalamin in men with obstructive and non-obstructive azoospermia.
Topics: Adult; Azoospermia; Chromatography, High Pressure Liquid; Folic Acid; Homocysteine; Humans; Luminescence; Male; Semen; Statistics, Nonparametric; Vitamin B 12 | 2010 |
Association of omega-3 fatty acids and homocysteine concentrations in pre-eclampsia.
Topics: Adult; Erythrocytes; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Folic Acid; Homocysteine; Humans; India; Life Style; Pre-Eclampsia; Pregnancy; Prenatal Nutritional Physiological Phenomena; Prospective Studies; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2011 |
Therapy: Vitamin B6, B9 and B12 in diabetic nephropathy--beware.
Topics: Cardiovascular Diseases; Diabetic Nephropathies; Disease Progression; Down-Regulation; Folic Acid; Homocysteine; Humans; Randomized Controlled Trials as Topic; Vitamin B 12; Vitamin B 6; Vitamins | 2010 |
Levels of plasma homocysteine in pseudoexfoliation glaucoma.
Topics: Aged; Exfoliation Syndrome; Female; Folic Acid; Glaucoma, Open-Angle; Homocysteine; Humans; Luminescent Measurements; Male; Vitamin B 12 | 2011 |
Plasma homocysteine and cognition in elderly patients with dementia or other psychogeriatric diseases.
Topics: Aged; Aged, 80 and over; Cognition; Cognition Disorders; Creatinine; Dementia; Diagnostic and Statistical Manual of Mental Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Middle Aged; Neuropsychological Tests; Regression Analysis; Tomography, X-Ray Computed; Vascular Diseases; Vitamin B 12 | 2010 |
Vitamin B12 and folic acid supplementation and plasma total homocysteine concentrations in pregnant Indian women with low B12 and high folate status.
Topics: Adult; Dietary Supplements; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Nutritional Status; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Rural Population; Vitamin B 12; Vitamin B 12 Deficiency | 2010 |
The transcobalamin (TCN2) 776C>G polymorphism affects homocysteine concentrations among subjects with low vitamin B(12) status.
Topics: Adult; Genotype; Homocysteine; Homozygote; Humans; Ireland; Male; Middle Aged; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12; Vitamin B Deficiency | 2010 |
Anemia in older persons.
Topics: Aged; Algorithms; Anemia; Deficiency Diseases; Erythrocyte Indices; Female; Ferritins; Folic Acid; Hematinics; Homocysteine; Humans; Inflammation; Iron Compounds; Male; Medical History Taking; Methylmalonic Acid; Physical Examination; Renal Insufficiency; Reticulocyte Count; Vitamin B 12 | 2010 |
Can B-vitamin therapy treat my kidney disease?
Topics: Health Knowledge, Attitudes, Practice; Homocysteine; Humans; Kidney Diseases; Vitamin B 12 | 2010 |
Serum folate, vitamin B-12, and homocysteine and their association with depressive symptoms among U.S. adults.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Depression; Diagnostic and Statistical Manual of Mental Disorders; Female; Folic Acid; Health Status; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Nutrition Surveys; Poverty; Psychiatric Status Rating Scales; Severity of Illness Index; Sex Factors; Surveys and Questionnaires; United States; Vitamin B 12 | 2010 |
Associations of folate, vitamin B12, homocysteine, and folate-pathway polymorphisms with prostate-specific antigen velocity in men with localized prostate cancer.
Topics: Aged; Biomarkers, Tumor; Disease Progression; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Prostate-Specific Antigen; Prostatic Neoplasms; Signal Transduction; Vitamin B 12 | 2010 |
Reductive cleavage mechanism of Co-C bond in cobalamin-dependent methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Carbon; Cobalt; Electron Transport; Homocysteine; Quantum Theory; Vitamin B 12 | 2010 |
The effect of homocysteine on the clinical outcomes of ventilated patients with severe sepsis.
Topics: Activated Protein C Resistance; Aged; Blood Coagulation Tests; Cohort Studies; Comorbidity; Factor V; Female; Folic Acid; Homocysteine; Homocystinuria; Hospital Mortality; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle Spasticity; Point Mutation; Protein C; Psychotic Disorders; Respiration, Artificial; Sepsis; Shock, Septic; Thrombophilia; Vitamin B 12 | 2010 |
Germline variation in the MTHFR and MTRR genes determines the nadir of bone density in pediatric acute lymphoblastic leukemia: a prospective study.
Topics: Absorptiometry, Photon; Adolescent; Biomarkers, Tumor; Bone Density; Case-Control Studies; Child; Child, Preschool; Ferredoxin-NADP Reductase; Folic Acid; Fractures, Bone; Genotype; Germ Cells; Homocysteine; Humans; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Vitamin B 12 | 2011 |
Beauty and the beast: B12, homocysteine, and the brain: a bemusing saga!
Topics: Brain; Homocysteine; Humans; Nervous System Diseases; Vitamin B 12 | 2010 |
Prevention: B vitamins and CVD--failure to find a simple solution.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12; Vitamin B Complex | 2010 |
[The relationship of methylenetetrahydrofolate reductase G1793A gene polymorphism, hyperhomocysteinaemia and ulcerative colitis].
Topics: Adult; Case-Control Studies; Colitis, Ulcerative; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12 | 2010 |
Serum vitamin B12 concentrations within reference values do not exclude functional vitamin B12 deficiency in PKU patients of various ages.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Female; Homocysteine; Humans; Infant; Male; Methylmalonic Acid; Phenylketonurias; Reference Values; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2011 |
Homocysteine, folic acid and vitamin B12 levels in maternal and umbilical cord plasma and homocysteine levels in placenta in pregnant women with pre-eclampsia.
Topics: Adult; Case-Control Studies; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Nutritional Status; Placenta; Pre-Eclampsia; Pregnancy; Severity of Illness Index; Vitamin B 12 | 2011 |
Global DNA methylation patterns in placenta and its association with maternal hypertension in pre-eclampsia.
Topics: Blood Pressure; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Hypertension; Infant, Newborn; Mothers; Placenta; Pre-Eclampsia; Pregnancy; Premature Birth; Term Birth; Vitamin B 12 | 2011 |
Vitamin B12 status, homocysteine and mortality amongst community-dwelling Irish elders.
Topics: Aged; Female; Homocysteine; Humans; Ireland; Kaplan-Meier Estimate; Male; Mortality; Proportional Hazards Models; Prospective Studies; Residence Characteristics; Vitamin B 12 | 2011 |
Contributions of enriched cereal-grain products, ready-to-eat cereals, and supplements to folic acid and vitamin B-12 usual intake and folate and vitamin B-12 status in US children: National Health and Nutrition Examination Survey (NHANES), 2003-2006.
Topics: Adolescent; Child; Child, Preschool; Dietary Supplements; Edible Grain; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Infant; Male; Methylmalonic Acid; Nutrition Surveys; Time Factors; Vitamin B 12 | 2011 |
Carbonyl proteins as a clinical marker in Alzheimer's disease and its relation to tryptophan degradation and immune activation.
Topics: Aged; Alzheimer Disease; Biomarkers; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neopterin; Oxidative Stress; Protein Carbonylation; Reference Values; Tryptophan; Vitamin B 12 | 2010 |
Serum asymmetric dimethylarginine (ADMA), homocysteine, vitamin B(12), folate levels, and lipid profiles in epileptic children treated with valproic acid.
Topics: Adolescent; Anticonvulsants; Arginine; Biomarkers; Case-Control Studies; Child; Child, Preschool; Cholesterol; Cross-Sectional Studies; Drug Administration Schedule; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Triglycerides; Valproic Acid; Vitamin B 12; Vitamin B Complex | 2011 |
Serum total homocystein, folate and vitamin B12 levels and their correlation with antipsychotic drug doses in adult male patients with chronic schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Case-Control Studies; Chlorpromazine; Chronic Disease; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Humans; Luminescent Measurements; Male; Middle Aged; Schizophrenia; Statistics, Nonparametric; Vitamin B 12 | 2010 |
Effect of cigarette smoking on plasma homocysteine concentrations.
Topics: Adult; Cotinine; Female; Folic Acid; Homocysteine; Humans; Male; Smoking; Thiocyanates; Vitamin B 12 | 2011 |
Homocysteine is a determinant of ApoA-I and both are associated with ankle brachial index, in an ambulatory elderly population.
Topics: Age Factors; Aged; Aged, 80 and over; Ankle Brachial Index; Apolipoprotein A-I; Biomarkers; Cholesterol, HDL; Female; Folic Acid; Homocysteine; Humans; Independent Living; Male; Methylmalonic Acid; Middle Aged; Particle Size; Peripheral Arterial Disease; Regression Analysis; Risk Assessment; Risk Factors; Sicily; Vitamin B 12; Walking | 2011 |
Folate, vitamin B₁₂ and total homocysteine levels in Arab adolescent subjects: reference ranges and potential determinants.
Topics: Adolescent; Age Factors; Arabs; Biomarkers; Body Mass Index; Cardiovascular Diseases; Child; Cross-Sectional Studies; Diet; Female; Folic Acid; Homocysteine; Humans; Kuwait; Logistic Models; Male; Motor Activity; Reference Values; Risk Factors; Sex Factors; Socioeconomic Factors; Vitamin B 12; Vitamin B Complex; Young Adult | 2012 |
Methyl deficient diet aggravates experimental colitis in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Choline Deficiency; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Dextran Sulfate; Diet; Folic Acid; Folic Acid Deficiency; Glutathione Peroxidase; Homocysteine; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phospholipases A2; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; RNA, Messenger; Superoxide Dismutase; Tissue Inhibitor of Metalloproteinase-3; Tumor Necrosis Factor-alpha; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
A single nucleotide polymorphism in transcobalamin II (I5V) induces structural changes in the protein as revealed by molecular modeling studies.
Topics: Binding Sites; Homocysteine; Humans; Ligands; Molecular Dynamics Simulation; Mutation; Polymorphism, Single Nucleotide; Principal Component Analysis; Protein Structure, Tertiary; Transcobalamins; Vitamin B 12 | 2011 |
Foreword to special issue on homocysteine disorders.
Topics: Congresses as Topic; Dietary Supplements; Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Diseases; Metabolic Networks and Pathways; Metabolism, Inborn Errors; Vitamin B 12 | 2011 |
Evaluation of the roles of serum vitamin B(12), folate and homocysteine levels in laryngeal squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Case-Control Studies; Demography; Folic Acid; Homocysteine; Humans; Laryngeal Neoplasms; Middle Aged; Vitamin B 12 | 2010 |
Methyl Vitamin B12 but not methylfolate rescues a motor neuron-like cell line from homocysteine-mediated cell death.
Topics: Animals; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Dose-Response Relationship, Drug; Homocysteine; Inhibitory Concentration 50; Mice; Motor Neurons; Neuroblastoma; Neuroprotective Agents; Reactive Oxygen Species; Tetrahydrofolates; Time Factors; Vitamin B 12; Vitamin B Complex | 2011 |
Serum homocysteine as a biomarker of vitiligo vulgaris severity: a pilot study.
Topics: Biomarkers; Folic Acid; Homocysteine; Pilot Projects; Vitamin B 12; Vitiligo | 2011 |
No relation between folate and homocysteine levels and depression in early pregnant women.
Topics: Adult; Cross-Sectional Studies; Depression; Diet; Female; Folic Acid; Homocysteine; Humans; Japan; Odds Ratio; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Psychiatric Status Rating Scales; Vitamin B 12; Vitamin B 6 | 2010 |
Folate and cobalamin status in relation to diet in healthy 2-y-old children.
Topics: Child, Preschool; Dairy Products; Diet; Diet Records; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Methylmalonic Acid; Multivariate Analysis; Norway; Nutrition Policy; Nutritional Status; Transcobalamins; Vitamin B 12; Vitamin B Complex | 2011 |
Polyneuropathy and dementia in old age: common inflammatory and vascular parameters.
Topics: Aged; Aged, 80 and over; Aging; Cognition Disorders; Cohort Studies; Dementia; Female; Folic Acid; Geriatrics; Homocysteine; Humans; Inflammation; Male; Mental Status Schedule; Neopterin; Neural Conduction; Polyneuropathies; Sural Nerve; Vascular Diseases; Vitamin B 12 | 2011 |
Inborn errors of cobalamin absorption and metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Anemia, Megaloblastic; Cobamides; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Malabsorption Syndromes; Metabolism, Inborn Errors; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Neonatal Screening; Proteinuria; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Interactions between genetic variants of folate metabolism genes and lifestyle affect plasma homocysteine concentrations in the Boston Puerto Rican population.
Topics: Aged; Alcohol Drinking; Alleles; Boston; Cross-Sectional Studies; Female; Folic Acid; Gene-Environment Interaction; Genetic Predisposition to Disease; Genotype; Glutamate Carboxypeptidase II; Homocysteine; Humans; Life Style; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Motor Activity; Polymorphism, Single Nucleotide; Proton-Coupled Folate Transporter; Puerto Rico; Sex Factors; Smoking; Vitamin B 12 | 2011 |
Hyperhomocysteinemia decreases bone blood flow.
Topics: Animals; Biomarkers; Biomechanical Phenomena; Blood Pressure; Bone Density; Bone Remodeling; Disease Models, Animal; Folic Acid; Homocysteine; Hyperhomocysteinemia; Laser-Doppler Flowmetry; Male; Osteoporosis; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Tibia; Time Factors; Up-Regulation; Vitamin B 12 | 2011 |
Folate and vitamin B12 improved alcohol-induced hyperhomocysteinemia in rats.
Topics: Animals; Cytochromes; Folic Acid; Homocysteine; Hyperhomocysteinemia; Liver; Liver Cirrhosis, Alcoholic; Liver Function Tests; Male; Matrix Metalloproteinase 2; Rats; Rats, Wistar; Vitamin B 12; Vitamin B Complex | 2011 |
Physiologic changes in homocysteine metabolism in pregnancy: a longitudinal study in Spain.
Topics: Adult; Diabetes, Gestational; Dietary Supplements; Female; Fetal Growth Retardation; Folic Acid; Genotype; Homocysteine; Humans; Hypertension, Pregnancy-Induced; Longitudinal Studies; Methylenetetrahydrofolate Reductase (NADPH2); Nutrition Policy; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Prevalence; Spain; Vitamin B 12 | 2011 |
A U-shaped relationship between plasma folate and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition.
Topics: Adult; Aged; Alcohol Drinking; Body Mass Index; Case-Control Studies; Cotinine; Diabetes Complications; DNA-Binding Proteins; Europe; Female; Flavin Mononucleotide; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Logistic Models; Male; Methionine; Middle Aged; Odds Ratio; Pancreatic Neoplasms; Prospective Studies; Pyridoxal Phosphate; Riboflavin; Risk Factors; Sex Factors; Smoking; Transcription Factors; Vitamin B 12; Vitamin B Complex | 2011 |
Effects of altered maternal folic acid, vitamin B12 and docosahexaenoic acid on placental global DNA methylation patterns in Wistar rats.
Topics: Animals; Diet; DNA Methylation; Docosahexaenoic Acids; Fatty Acids; Feeding Behavior; Female; Folic Acid; Homocysteine; Placenta; Pregnancy; Rats; Reproduction; Vitamin B 12 | 2011 |
What is the meaning of homocysteine in patients on dialysis?
Topics: Adult; Aged; Biomarkers; Brazil; C-Reactive Protein; Creatine Kinase; Creatinine; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Interleukin-6; Kidney Failure, Chronic; Linear Models; Lipids; Male; Malnutrition; Middle Aged; Peritoneal Dialysis; Prevalence; Renal Dialysis; Risk Factors; Tumor Necrosis Factor-alpha; Vitamin B 12 | 2011 |
[Significance of plasmic homocysteine, folate and Vitamin B(12) in ulcerative colitis].
Topics: Adolescent; Adult; Aged; Case-Control Studies; Colitis, Ulcerative; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12; Young Adult | 2011 |
Vitamin B12 deficiency, hyperhomocysteinemia and thrombosis: a case and control study.
Topics: Adult; Aged; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Middle Aged; Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Diagnostic accuracy of holotranscobalamin, methylmalonic acid, serum cobalamin, and other indicators of tissue vitamin B₁₂ status in the elderly.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Discriminant Analysis; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Kidney Diseases; Kidney Function Tests; Linear Models; Male; Methylmalonic Acid; Middle Aged; Predictive Value of Tests; Reference Values; ROC Curve; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2011 |
The MMACHC proteome: hallmarks of functional cobalamin deficiency in humans.
Topics: Amino Acid Metabolism, Inborn Errors; Carrier Proteins; Cell Line; Cells, Cultured; Fibroblasts; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Intracellular Space; Metabolic Networks and Pathways; Methylmalonic Acid; Mutation; Oxidoreductases; Phenotype; Proteome; Vimentin; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2011 |
Vitamin B12 and folate deficiency and elevated plasma total homocysteine in workers with chronic exposure to chromate.
Topics: Adult; China; Chromates; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2011 |
Vitamin supplementation reduces the level of homocysteine in the urine of autistic children.
Topics: Autistic Disorder; Child; Child, Preschool; Creatinine; Dietary Supplements; Female; Folic Acid; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Vitamin B 12; Vitamin B 6 | 2011 |
Electronic structure of cofactor-substrate reactant complex involved in the methyl transfer reaction catalyzed by cobalamin-dependent methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Electrons; Escherichia coli; Homocysteine; Models, Molecular; Protein Conformation; Quantum Theory; Thermotoga maritima; Vitamin B 12 | 2011 |
A longitudinal study of maternal folate and vitamin B12 status in pregnancy and postpartum, with the same infant markers at 6 months of age.
Topics: Adult; Australia; Biomarkers; Breast Feeding; Cross-Sectional Studies; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Infant; Longitudinal Studies; Luminescent Measurements; Postpartum Period; Pregnancy; Pregnancy Complications; Socioeconomic Factors; Vitamin B 12; Vitamin B Complex; Young Adult | 2012 |
Lipid profiles and oxidative stress parameters in male and female hemodialysis patients.
Topics: Aged; Atherosclerosis; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Lipids; Lipoproteins, LDL; Male; Middle Aged; Oxidative Stress; Renal Dialysis; Risk Assessment; Risk Factors; Triglycerides; Vitamin B 12 | 2011 |
Plasma homocysteine and cognitive decline in older hypertensive subjects.
Topics: Aged; Aged, 80 and over; Aging; Biomarkers; Cognition; Cognition Disorders; Executive Function; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hypertension; Male; Neuropsychological Tests; Risk Factors; Vitamin B 12 | 2011 |
Maternal folate, vitamin B12 and homocysteine levels in pregnancies affected by congenital malformations other than neural tube defects.
Topics: Congenital Abnormalities; Female; Folic Acid; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Risk Factors; Vitamin B 12 | 2011 |
The folate hydrolase 1561C>T polymorphism is associated with depressive symptoms in Puerto Rican adults.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Boston; Cross-Sectional Studies; Depression; Female; Folate Receptor 1; Folic Acid; Folic Acid Deficiency; gamma-Glutamyl Hydrolase; Gene Frequency; Genotype; Glutamate Carboxypeptidase II; Homocysteine; Humans; Linear Models; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Proton-Coupled Folate Transporter; Psychiatric Status Rating Scales; Pteroylpolyglutamic Acids; Puerto Rico; Pyridoxal Phosphate; Reduced Folate Carrier Protein; Vitamin B 12 | 2011 |
Genetic and environmental determinants of plasma total homocysteine levels: impact of population-wide folate fortification.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Austria; Edible Grain; Environment; Female; Ferredoxin-NADP Reductase; Folic Acid; Folic Acid Antagonists; Food, Fortified; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Sex Characteristics; Smoking; United States; Vitamin B 12 | 2011 |
The basis of differential responses to folic acid supplementation.
Topics: Aged; Aged, 80 and over; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Models, Genetic; Nutrigenomics; Polymorphism, Single Nucleotide; Twins, Dizygotic; Twins, Monozygotic; Vitamin B 12 | 2011 |
Do high blood folate concentrations exacerbate metabolic abnormalities in people with low vitamin B-12 status?
Topics: Adult; Cross-Sectional Studies; Female; Ferritins; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2011 |
Update on vitamin B12 deficiency.
Topics: Administration, Oral; Adult; Aged; Biomarkers; Dietary Supplements; Geriatric Assessment; Homocysteine; Humans; Middle Aged; Practice Guidelines as Topic; Risk Factors; United States; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
TT genotype of the methylenetetrahydrofolate reductase C677T polymorphism is an important determinant for homocysteine levels in multi-ethnic Malaysian ischaemic stroke patients.
Topics: China; Ethnicity; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; India; Malaysia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymorphism, Genetic; Stroke; Vitamin B 12 | 2011 |
Elevated maternal serum folate in the third trimester and reduced fetal growth: a longitudinal study.
Topics: Adult; Biomarkers; Birth Weight; Body Height; Dietary Supplements; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Infant; Longitudinal Studies; Nutritional Status; Pregnancy; Pregnancy Trimester, Third; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Pyridoxal; Vitamin B 12; Vitamin B Complex; Weight Gain | 2011 |
Association between dietary folate intake and blood status of folate and homocysteine in Malaysian adults.
Topics: Adult; Asian People; Cardiovascular Diseases; Cross-Sectional Studies; Diet; Diet Records; Diet Surveys; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Linear Models; Malaysia; Male; Middle Aged; Neural Tube Defects; Nutritional Status; Sex Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Young Adult | 2011 |
Homocysteine and cognitive function in very elderly nondemented subjects.
Topics: Aged, 80 and over; Apolipoprotein E4; Cognition; Executive Function; Female; Folic Acid; Homocysteine; Humans; Male; Neuropsychological Tests; Vitamin B 12 | 2011 |
Homocysteine in Alzheimer's disease: role of dietary folate, vitamin B6 and B12.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Diet; Diet Records; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12; Vitamin B 6 | 2011 |
Time for a rethink of vitamin B12 injections?
Topics: Administration, Oral; Developing Countries; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Injections, Intramuscular; New Zealand; Pregnancy; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Persistent homocysteine metabolism abnormality accelerates cardiovascular disease in hemodialyzed patients--the Nishinomiya Study.
Topics: Body Mass Index; Cardiovascular Diseases; Creatinine; Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Middle Aged; Prospective Studies; Renal Dialysis; Vitamin B 12 | 2012 |
Efficacy of flour fortification with folic acid in women of childbearing age in Iran.
Topics: Adolescent; Adult; Bread; Cross-Sectional Studies; Female; Flour; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Iran; Longitudinal Studies; Middle Aged; Neural Tube Defects; Nutritional Status; Socioeconomic Factors; Vitamin B 12; Young Adult | 2011 |
Serum asymmetric dimethylarginine, nitrate, vitamin B(12), and homocysteine levels in individuals with pulmonary embolism.
Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Female; Homocysteine; Humans; Male; Middle Aged; Nitrates; Oxygen; Partial Pressure; Predictive Value of Tests; Prognosis; Pulmonary Embolism; Pulmonary Wedge Pressure; Risk Factors; Vitamin B 12 | 2011 |
Homocysteine and asymmetric dimethylarginine in relation to B vitamins in elderly people.
Topics: Aged; Aged, 80 and over; Arginine; Biological Availability; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hypercholesterolemia; Male; Nitric Oxide; Nitric Oxide Synthase; Statistics as Topic; Vasodilation; Vitamin B 12; Vitamin B 6 | 2011 |
Association of cognitive impairment with combinations of vitamin B₁₂-related parameters.
Topics: Aged; Biomarkers; Case-Control Studies; Cognition Disorders; Cross-Sectional Studies; Homocysteine; Humans; Methylmalonic Acid; Risk Assessment; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Zinc-homocysteine binding in cobalamin-dependent methionine synthase and its role in the substrate activation: DFT, ONIOM, and QM/MM molecular dynamics studies.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biocatalysis; Catalytic Domain; Homocysteine; Humans; Models, Molecular; Molecular Dynamics Simulation; Protein Binding; Protein Structure, Tertiary; Vitamin B 12; Zinc | 2011 |
Folate and vitamin B12 in idiopathic male infertility.
Topics: Adult; Case-Control Studies; Folic Acid; Homocysteine; Humans; Infertility, Male; Male; Middle Aged; Sweden; Vitamin B 12 | 2011 |
Cross-sectional and longitudinal association between homocysteine, vitamin B12 and physical performance in older persons.
Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Exercise Test; Female; Homocysteine; Humans; Longitudinal Studies; Male; Movement; Netherlands; Physical Fitness; Risk Factors; Sex Factors; Vitamin B 12; Walking | 2012 |
Uptake of cobalamin and markers of cobalamin status: a longitudinal study of healthy pregnant women.
Topics: Adult; Biomarkers; Denmark; Female; Homocysteine; Humans; Longitudinal Studies; Methylmalonic Acid; Pregnancy; Pregnancy Trimesters; Transcobalamins; Vitamin B 12 | 2011 |
Association of MTHFR and RFC1 gene polymorphism with hyperhomocysteinemia and its modulation by vitamin B12 and folic acid in an Indian population.
Topics: Adult; Alleles; Female; Folic Acid; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; Polymorphism, Single Nucleotide; Prevalence; Replication Protein C; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamin B Deficiency | 2012 |
Homocysteine, vitamin B12, and folic acid levels in Alzheimer's disease, mild cognitive impairment, and healthy elderly: baseline characteristics in subjects of the Australian Imaging Biomarker Lifestyle study.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Analysis of Variance; Australia; Brain; Cognitive Dysfunction; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Vitamin B 12 | 2011 |
Vitamin B-12 and homocysteine status in a folate-replete population: results from the Canadian Health Measures Survey.
Topics: Adolescent; Adult; Aged; Biomarkers; Canada; Child; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Health Surveys; Homocysteine; Humans; Legislation, Food; Male; Middle Aged; Nutritional Status; Obesity; Prevalence; Severity of Illness Index; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2011 |
Arterial function of carotid and brachial arteries in postmenopausal vegetarians.
Topics: Age Factors; Aging; Biomarkers; Blood Glucose; Brachial Artery; C-Reactive Protein; Carotid Artery, Common; Chi-Square Distribution; Compliance; Cross-Sectional Studies; Diet, Vegetarian; Female; Homocysteine; Humans; Linear Models; Lipids; Lipoprotein(a); Middle Aged; Postmenopause; Pulsatile Flow; Taiwan; Ultrasonography, Doppler, Pulsed; Vascular Resistance; Vitamin B 12 | 2011 |
Plasma choline concentration varies with different dietary levels of vitamins B6, B12 and folic acid in rats maintained on choline-adequate diets.
Topics: Animals; Biological Availability; Choline; Diet; Dietary Supplements; Folic Acid; Homocysteine; Male; Methylation; Rats; Rats, Sprague-Dawley; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2012 |
Bone mineral density is not associated with homocysteine level, folate and vitamin B12 status.
Topics: Absorptiometry, Photon; Age Factors; Aged; Alcohol Drinking; Bone Density; Croatia; Erythrocytes; Estrogen Replacement Therapy; Female; Folic Acid; Homocysteine; Humans; Life Style; Middle Aged; Postmenopause; Vitamin B 12 | 2012 |
A folate receptor alpha double-mutated haplotype 1816delC-1841A is distributed throughout Eurasia and associated with lower erythrocyte folate levels.
Topics: Adult; Alleles; Asia; Base Pairing; Erythrocytes; Europe; Female; Folate Receptor 1; Folic Acid; Haplotypes; Homocysteine; Humans; Male; Mutation; Polymerase Chain Reaction; Prevalence; Vitamin B 12 | 2012 |
Hyperhomocysteinemia and related genetic polymorphisms correlate with ulcerative colitis in Chinese Han population in Central China [corrected].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Alleles; Amino Acid Substitution; Asian People; China; Colitis, Ulcerative; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Vitamin B 12 | 2012 |
Serum homocysteine and folate but not vitamin B12 are predictors of CHD mortality in older adults.
Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Coronary Disease; Down-Regulation; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; New South Wales; Prognosis; Proportional Hazards Models; Risk Assessment; Risk Factors; Up-Regulation; Vitamin B 12 | 2012 |
[Serum levels of antioxidants and vitamins related to the homocystein's metabolism during postmenopause].
Topics: Abdominal Fat; Antioxidants; Body Mass Index; Cross-Sectional Studies; Estrogens; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Hormone Replacement Therapy; Humans; Hyperhomocysteinemia; Middle Aged; Motor Activity; Overweight; Postmenopause; Progesterone; Risk; Urban Population; Vitamin B 12; Vitamin B 6; Waist-Hip Ratio | 2005 |
[Hyperhomocysteinemia and schizophrenia: case control study].
Topics: Adult; Case-Control Studies; Chronic Disease; Comorbidity; Cross-Sectional Studies; Female; Fluorescence Polarization Immunoassay; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Reference Values; Schizophrenia; Schizophrenic Psychology; Statistics as Topic; Vitamin B 12 | 2011 |
Folate, vitamin B12, vitamin B6 and homocysteine: impact on pregnancy outcome.
Topics: Adult; Biomarkers; Dietary Supplements; DNA Damage; Erythrocyte Count; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Logistic Models; Multivariate Analysis; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Prospective Studies; South Australia; Vitamin B 12; Vitamin B 6 | 2013 |
Folate, homocysteine, vitamin B12, and polymorphisms of genes participating in one-carbon metabolism in late-onset Alzheimer's disease patients and healthy controls.
Topics: Age of Onset; Aged; Alleles; Alzheimer Disease; Biomarkers; Case-Control Studies; Female; Folic Acid; Genotype; Health; Homocysteine; Humans; Male; Polymorphism, Genetic; Vitamin B 12 | 2012 |
Modulator effects of the methylenetetrahydrofolate reductase C677T polymorphism on response to vitamin B12 therapy and homocysteine metabolism.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Vitamin B₁₂ deficiency & cognitive impairment in elderly population.
Topics: Diet, Vegetarian; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Vitamin B₁₂ deficiency & levels of metabolites in an apparently normal urban south Indian elderly population.
Topics: Aged; Diet, Vegetarian; Erythrocytes; Female; Folic Acid; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; India; Male; Methylmalonic Acid; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Do we need to reconsider the desirable blood level of vitamin B12?
Topics: Age Factors; Homocysteine; Humans; Methylmalonic Acid; Prognosis; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Folate and vitamin B12-related genes and risk for omphalocele.
Topics: Folic Acid; Genetic Predisposition to Disease; Genotype; Hernia, Umbilical; Homocysteine; Humans; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Pilot Projects; Polymorphism, Single Nucleotide; Receptors, Cell Surface; Risk; Vitamin B 12 | 2012 |
Comments on "Vitamin supplementation reduces the level of homocysteine in the urine of autistic children".
Topics: Autistic Disorder; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12; Vitamin B 6 | 2011 |
Vitamin B12 and homocysteine levels and 6-year change in peripheral nerve function and neurological signs.
Topics: Aged; Analysis of Variance; Chi-Square Distribution; Female; Follow-Up Studies; Homocysteine; Humans; Logistic Models; Longitudinal Studies; Male; Middle Aged; Neural Conduction; Neurologic Examination; Peripheral Nervous System Diseases; Peroneal Nerve; Surveys and Questionnaires; Vitamin B 12 | 2012 |
Suppression of homocysteine levels by vitamin B12 and folates: age and gender dependency in the Jackson Heart Study.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Black or African American; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Middle Aged; Mississippi; Sex Factors; Vitamin B 12; Young Adult | 2012 |
Serum holotranscobalamine, vitamin B12, folic acid and homocysteine levels in patients with vitiligo.
Topics: Adult; Biomarkers; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Logistic Models; Male; Middle Aged; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Vitiligo; Young Adult | 2012 |
Understanding the complexity of homocysteine lowering with vitamins: the potential role of subgroup analyses.
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Data Interpretation, Statistical; Homocysteine; Humans; Kidney; Meta-Analysis as Topic; Methylenetetrahydrofolate Dehydrogenase (NADP); Polymorphism, Genetic; Reproducibility of Results; Risk Assessment; Stroke; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2011 |
Hyperhomocysteinemia among Omani autistic children: a case-control study.
Topics: Autistic Disorder; Biomarkers; Case-Control Studies; Child, Preschool; Fasting; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Reference Values; Vitamin B 12 | 2011 |
Holotranscobalamin: not ready for prime time.
Topics: Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Folate, vitamin B12 and homocysteine status in an Italian blood donor population.
Topics: Adolescent; Adult; Aged; Blood Donors; Chromatography, High Pressure Liquid; Feeding Behavior; Female; Folic Acid; Fruit; Homocysteine; Humans; Italy; Logistic Models; Male; Middle Aged; Motor Activity; Specimen Handling; Surveys and Questionnaires; Vegetables; Vitamin B 12; Young Adult | 2013 |
[Approaches to vitamin B12 deficiency].
Topics: Adult; Aged; Anemia, Iron-Deficiency; Diagnostic Services; Diet, Vegetarian; Female; Homocysteine; Humans; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Association of methylentetraydrofolate reductase (MTHFR) 677 C > T gene polymorphism and homocysteine levels in psoriasis vulgaris patients from Malaysia: a case-control study.
Topics: Adult; Case-Control Studies; Ethnicity; Female; Folic Acid; Genotype; Homocysteine; Humans; Malaysia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Psoriasis; Vitamin B 12 | 2012 |
Effect on risk of anencephaly of gene-nutrient interactions between methylenetetrahydrofolate reductase C677T polymorphism and maternal folate, vitamin B12 and homocysteine profile.
Topics: Adult; Anencephaly; Case-Control Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Mexico; Polymorphism, Genetic; Pregnancy; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex | 2012 |
Serum homocysteine level and its association with folic acid and vitamin B12 in the third trimester of pregnancies complicated with intrauterine growth restriction.
Topics: Adult; Female; Fetal Growth Retardation; Fetal Weight; Folic Acid; Homocysteine; Humans; Pregnancy; Pregnancy Trimester, Third; Vitamin B 12; Young Adult | 2011 |
Hepatitis C virus co-infection and sexual risk behaviour are associated with a high homocysteine serum level in HIV-infected patients.
Topics: Adult; Cardiovascular Diseases; Coinfection; Cross-Sectional Studies; Female; Folic Acid; Hepacivirus; Hepatitis C; HIV; HIV Infections; Homocysteine; Humans; Male; Risk Factors; Risk-Taking; Sexual Behavior; Vitamin B 12 | 2012 |
Methylmalonic acid and homocysteine assessment in the detection of vitamin B12 deficiency in patients with bilateral visual loss.
Topics: Adult; Aged, 80 and over; Blindness; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2012 |
Vision changes after spaceflight are related to alterations in folate- and vitamin B-12-dependent one-carbon metabolism.
Topics: Adult; Astronauts; Carbon Dioxide; Citrates; Cystathionine; Female; Folic Acid; Homocysteine; Humans; Male; Metabolic Networks and Pathways; Methylmalonic Acid; Middle Aged; Models, Biological; Refraction, Ocular; Space Flight; Vision Disorders; Vitamin B 12 | 2012 |
MTHFR C677T polymorphism, homocysteine and B-vitamins status in a sample of Chinese and Malay subjects in Universiti Putra Malaysia.
Topics: Adult; Asian People; Coronary Artery Disease; Cross-Sectional Studies; DNA; DNA Primers; Female; Homocysteine; Humans; Malaysia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Genetic; Students; Vitamin B 12; Young Adult | 2011 |
Elevated plasma homocysteine in association with decreased vitamin B(12), folate, serotonin, lipids and lipoproteins in depressed patients.
Topics: Adult; Cholesterol; Depressive Disorder; Female; Folic Acid; Homocysteine; Humans; Lipids; Lipoproteins; Male; Middle Aged; Risk Factors; Serotonin; Sex Distribution; Vitamin B 12; Young Adult | 2012 |
The Mediterranean diet and fetal size parameters: the Generation R Study.
Topics: Adult; Birth Weight; C-Reactive Protein; Diet, Mediterranean; Energy Intake; Feeding Behavior; Female; Fetal Development; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Logistic Models; Netherlands; Organ Size; Patient Compliance; Placenta; Pregnancy; Prenatal Nutritional Physiological Phenomena; Prospective Studies; Qualitative Research; Surveys and Questionnaires; Vitamin B 12; White People | 2012 |
Coenzyme Q10, hyperhomocysteinemia and MTHFR C677T polymorphism in levodopa-treated Parkinson's disease patients.
Topics: Aged; Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic; Ubiquinone; Vitamin B 12 | 2012 |
Reductive elimination pathway for homocysteine to methionine conversion in cobalamin-dependent methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Homocysteine; Methionine; Models, Molecular; Oxidation-Reduction; Quantum Theory; Vitamin B 12 | 2012 |
Plasma homocysteine concentrations in mothers and term and preterm newborns.
Topics: Adult; Female; Gestational Age; Homocysteine; Humans; Infant, Newborn; Infant, Premature; Mothers; Pregnancy; Pregnancy Complications; Prenatal Diagnosis; Reference Values; Vitamin B 12; Young Adult | 2011 |
Marked gender difference in plasma total homocysteine concentrations in indian adults with low vitamin B₁₂.
Topics: Adult; Age Factors; Body Composition; Erythrocytes; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Role of folic acid depletion on homocysteine serum level in children and adolescents with epilepsy and different MTHFR C677T genotypes.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Vitamin B 12 | 2012 |
[Skin lesions induced by malnutrition in an infant with methylmalonic aciduria and homocysteic acidemia].
Topics: Homocysteine; Humans; Infant; Infant Nutrition Disorders; Male; Methylmalonic Acid; Skin Diseases; Vitamin B 12 | 2012 |
Homocysteine and hydroxyproline levels in patients with primary open-angle glaucoma.
Topics: Aged; Aqueous Humor; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Folic Acid; Glaucoma, Open-Angle; Homocysteine; Humans; Hydroxyproline; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Spectrum Analysis; Vitamin B 12; Vitamin B 6 | 2012 |
Polymorphisms in MTHFR, MS and CBS genes and homocysteine levels in a Pakistani population.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Cystathionine beta-Synthase; Female; Folic Acid; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Pakistan; Polymorphism, Single Nucleotide; Pyridoxal Phosphate; Risk Factors; Sex Factors; Vitamin B 12; Young Adult | 2012 |
Homocysteine and folate concentrations in early pregnancy and the risk of adverse pregnancy outcomes: the Generation R Study.
Topics: Adult; Birth Weight; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Male; Netherlands; Organ Size; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Risk Factors; Vitamin B 12; Young Adult | 2012 |
Folate intake and incidence of hypertension among American young adults: a 20-y follow-up study.
Topics: Adolescent; Adult; Black or African American; Blood Pressure; Diet; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hypertension; Incidence; Interviews as Topic; Longitudinal Studies; Male; Proportional Hazards Models; Prospective Studies; Regression Analysis; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; White People; Young Adult | 2012 |
Serum folate, total homocysteine levels and methylenetetrahydrofolate reductase 677C>T polymorphism in young healthy female Japanese.
Topics: Adolescent; Amplified Fragment Length Polymorphism Analysis; Child; Diet; Female; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Health Surveys; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Japan; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Vascular Diseases; Vitamin B 12; Vitamin B 6 | 2012 |
A case-control nutrigenomic study on the synergistic activity of folate and vitamin B12 in cervical cancer progression.
Topics: Case-Control Studies; Drug Synergism; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; India; Logistic Models; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Nutrigenomics; Odds Ratio; Polymorphism, Genetic; Risk Assessment; Uterine Cervical Neoplasms; Vitamin B 12; Vitamin B Complex | 2012 |
Relationships among biomarkers of one-carbon metabolism.
Topics: Adult; Aging; Biomarkers; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; One-Carbon Group Transferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Characteristics; Vitamin B 12; Young Adult | 2012 |
Relationship between vitamin B12, folate and homocysteine levels and H. pylori infection in patients with functional dyspepsia: a cross-section study.
Topics: Adult; Aged; Cross-Sectional Studies; Dyspepsia; Female; Folic Acid; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12 | 2012 |
[Correlation of homocysteine in plasma with NOS and endogenous CO in the penile corpus cavernosum of type 2 diabetic rats].
Topics: Animals; Carbon Monoxide; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Folic Acid; Homocysteine; Insulin; Male; Nitric Oxide Synthase; Penis; Rats; Rats, Wistar; Vitamin B 12 | 2012 |
Serum holotranscobalamine, vitamin B12, folic acid and homocysteine levels in alopecia areata patients.
Topics: Adolescent; Adult; Aged; Alopecia Areata; Child; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Male; Middle Aged; Transcobalamins; Vitamin B 12; Young Adult | 2013 |
Metabolic adaptation of Ralstonia solanacearum during plant infection: a methionine biosynthesis case study.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Homocysteine; Methionine; Methyltransferases; Plant Cells; Plant Diseases; Ralstonia solanacearum; Trans-Activators; Vitamin B 12 | 2012 |
Role of homocysteine & MTHFR C677T gene polymorphism as risk factors for coronary artery disease in young Indians.
Topics: Adult; Cholesterol; Coronary Artery Disease; Female; Folic Acid; Genetic Association Studies; Homocysteine; Humans; Hyperhomocysteinemia; India; Lipoproteins, HDL; Lipoproteins, LDL; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Smoking; Triglycerides; Vitamin B 12 | 2012 |
Plasma phospholipid polyunsaturated fatty acids and homocysteine in Chinese type 2 diabetes patients.
Topics: Adult; Aged; Algorithms; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Outpatient Clinics, Hospital; Phospholipids; Prevalence; Vitamin B 12 | 2012 |
Homocysteinylation of neuronal proteins contributes to folate deficiency-associated alterations of differentiation, vesicular transport, and plasticity in hippocampal neuronal cells.
Topics: Animals; Blotting, Western; Cell Differentiation; Cell Line; Cell Movement; Cell Survival; Cells, Cultured; Folic Acid; Folic Acid Deficiency; Hep G2 Cells; Hippocampus; Homocysteine; Humans; Immunohistochemistry; Neurons; Protein Binding; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Vitamin B 12 | 2012 |
Cervical cancer pathogenesis is associated with one-carbon metabolism.
Topics: Adult; Aged; Antigens, CD; Cadherins; Carbon; DNA Methylation; Female; Folic Acid; Genotype; Homocysteine; Humans; Kruppel-Like Transcription Factors; Middle Aged; Papillomaviridae; Papillomavirus Infections; Receptors, Retinoic Acid; Uterine Cervical Neoplasms; Vitamin B 12 | 2012 |
Status of vitamins B-12 and B-6 but not of folate, homocysteine, and the methylenetetrahydrofolate reductase C677T polymorphism are associated with impaired cognition and depression in adults.
Topics: Adult; Aged; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Depression; Female; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6 | 2012 |
Reduced folate, increased vitamin B(12) and homocysteine concentrations in women delivering preterm.
Topics: Adult; Birth Weight; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Maternal Nutritional Physiological Phenomena; Micronutrients; Nutrition Assessment; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Premature Birth; Vitamin B 12; Vitamin B Complex; Young Adult | 2012 |
A study of neurobehavioral, clinical psychometric, and P3 changes in vitamin B12 deficiency neurological syndrome.
Topics: Adolescent; Adult; Aged; Child; Cognition; Cognition Disorders; Event-Related Potentials, P300; Female; Follow-Up Studies; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Psychometrics; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2013 |
[The relation between plasma homocysteine level and amyotrophic lateral sclerosis].
Topics: Adult; Amyotrophic Lateral Sclerosis; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12 | 2012 |
Prevalence of MTHFR C677T and MS A2756G polymorphisms in major depressive disorder, and their impact on response to fluoxetine treatment.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Female; Fluoxetine; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pharmacogenetics; Polymorphism, Genetic; Prevalence; Psychiatric Status Rating Scales; Statistics, Nonparametric; Vitamin B 12; Young Adult | 2012 |
Cobalamin status in sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Black or African American; Cross-Sectional Studies; District of Columbia; Homocysteine; Hospitals, Teaching; Humans; Male; Methylmalonic Acid; Middle Aged; Nutritional Status; Prevalence; Prospective Studies; Renal Insufficiency, Chronic; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2013 |
Serum homocysteine, vitamin B12, folic acid levels and methylenetetrahydrofolate reductase (MTHFR) gene polymorphism in vitiligo.
Topics: Adolescent; Adult; Child; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Vitiligo | 2012 |
Serum cobalamin, urine methylmalonic acid, and plasma total homocysteine concentrations in Border Collies and dogs of other breeds.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Biomarkers; Chromatography, Gas; Chromatography, High Pressure Liquid; Dog Diseases; Dogs; Female; Homocysteine; Luminescence; Male; Methylmalonic Acid; Reference Values; Species Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Unmetabolized folic acid prevalence is widespread in the older Irish population despite the lack of a mandatory fortification program.
Topics: Aged; Aged, 80 and over; Aging; Cohort Studies; Cross-Sectional Studies; Diet; Erythrocytes; Female; Folic Acid; Food, Fortified; Health Promotion; Homocysteine; Humans; Ireland; Male; Middle Aged; Nutrition Policy; Vitamin B 12; Vitamin B 12 Deficiency; Voluntary Programs | 2012 |
Homocysteine, folate, vitamin B12 and B6 in mothers of children with neural tube defects in Xinjiang, China.
Topics: Adult; Biomarkers; Case-Control Studies; China; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Risk Factors; Vitamin B 12; Vitamin B 6 | 2012 |
Higher plasma homocysteine is associated with lower vitamin B6 status in critically ill surgical patients.
Topics: Aged; Critical Illness; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intensive Care Units; Male; Middle Aged; Nutritional Status; Postoperative Complications; Prevalence; Pyridoxal Phosphate; Vitamin B 12; Vitamin B 6 Deficiency; Vitamin B Complex | 2012 |
Association between ischemia-modified albumin, homocysteine, vitamin B(12) and folic acid in patients with severe sepsis.
Topics: Adolescent; Adult; Aged; Bacteremia; Biomarkers; C-Reactive Protein; Case-Control Studies; Female; Folic Acid; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Homocysteine; Humans; Male; Middle Aged; Serum Albumin; Serum Albumin, Human; Vitamin B 12; Young Adult | 2012 |
Effects of unconjugated bilirubin on chromosomal damage in individuals with Gilbert's syndrome measured with the micronucleus cytome assay.
Topics: Adult; Aged; Aged, 80 and over; Bilirubin; Chromosome Aberrations; Colorectal Neoplasms; Comet Assay; Cytokinesis; DNA Damage; Endpoint Determination; Female; Folic Acid; Gilbert Disease; Homocysteine; Humans; Lung Neoplasms; Lymphocytes; Male; Micronucleus Tests; Middle Aged; Vitamin B 12; Young Adult | 2012 |
Association of COMT, MTHFR, and SLC19A1(RFC-1) polymorphisms with homocysteine blood levels and cognitive impairment in Parkinson's disease.
Topics: Catechol O-Methyltransferase; Cognition Disorders; Female; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Parkinson Disease; Polymorphism, Genetic; Reduced Folate Carrier Protein; Vitamin B 12 | 2012 |
[Abnormal findings during newborn period of 160 patients with early-onset methylmalonic aciduria].
Topics: Amino Acid Metabolism, Inborn Errors; Carnitine; Child; Child, Preschool; China; Female; Folic Acid; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Male; Methylmalonic Acid; Neonatal Screening; Retrospective Studies; Vitamin B 12 | 2012 |
Do all the patients with gastric parietal cell antibodies have pernicious anemia?
Topics: Adult; Aged; Aged, 80 and over; Anemia, Pernicious; Antibodies; Autoantibodies; Case-Control Studies; Erythrocyte Indices; Female; Folic Acid; Hematinics; Hemoglobins; Homocysteine; Humans; Intrinsic Factor; Iron; Male; Middle Aged; Parietal Cells, Gastric; Sex Factors; Vitamin B 12; World Health Organization; Young Adult | 2013 |
Determinants of the essential one-carbon metabolism metabolites, homocysteine, S-adenosylmethionine, S-adenosylhomocysteine and folate, in cerebrospinal fluid.
Topics: Adult; Aged; Aging; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Immunoassay; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry; Vitamin B 12 | 2012 |
Maternal B vitamin status in pregnancy week 18 according to reported use of folic acid supplements.
Topics: Adult; Biomarkers; Dietary Supplements; Fatty Acids, Omega-3; Female; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methylmalonic Acid; Micronutrients; Norway; Pregnancy; Prospective Studies; Riboflavin; Socioeconomic Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2013 |
Elevated plasma homocysteine level is not primarily related to Alzheimer's disease.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Insufficiency; Risk Factors; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Relationship of cognitive function with B vitamin status, homocysteine, and tissue factor pathway inhibitor in cognitively impaired elderly: a cross-sectional survey.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins; Male; Mental Status Schedule; Neuropsychological Tests; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Efficacy of a 28-day oral cyanocobalamin supplementation on vitamin B status in Spanish institutionalized elderly.
Topics: Aged; Aged, 80 and over; Dietary Supplements; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Institutionalization; Male; Nutritional Status; Spain; Transcobalamins; Vitamin B 12; Vitamin B Deficiency | 2012 |
Homocysteine, folic acid and vitamin B12 levels in females with severe acne vulgaris.
Topics: Acne Vulgaris; Female; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 2012 |
Plasma homocysteine and vitamin B12 serum levels, red blood cell folate concentrations, C677T methylenetetrahydrofolate reductase gene mutation and risk of recurrent miscarriage: a case-control study in Spain.
Topics: Abortion, Spontaneous; Adult; Case-Control Studies; Erythrocytes; Female; Folic Acid; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Odds Ratio; Polymorphism, Single Nucleotide; Spain; Vitamin B 12 | 2013 |
Significant reduction of homocysteine level with multiple B vitamins in atrophic glossitis patients.
Topics: Adult; Aged; Aged, 80 and over; Atrophy; Dietary Supplements; Female; Folic Acid; Glossitis; Hematinics; Homocysteine; Humans; Iron; Male; Middle Aged; Tongue; Vitamin B 12; Vitamin B Complex; Young Adult | 2013 |
DNA damage response in monozygotic twins discordant for smoking habits.
Topics: Apoptosis; Comet Assay; Cross-Sectional Studies; DNA Damage; DNA Repair; Endpoint Determination; Environmental Exposure; Female; Folic Acid; Gamma Rays; Histones; Homocysteine; Humans; Kinetics; Linear Models; Lymphocytes; Male; Phosphorylation; Radiation Tolerance; Smoking; Twins, Monozygotic; Vitamin B 12 | 2013 |
Plasma homocysteine levels in dry eye patients.
Topics: Dry Eye Syndromes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoenzyme Techniques; Luminescent Measurements; Male; Middle Aged; Prospective Studies; Surveys and Questionnaires; Vitamin B 12 | 2013 |
Homocysteine, folate, vitamin B-12, and physical function in older adults: cross-sectional findings from the Singapore Longitudinal Ageing Study.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Gait; Geriatric Assessment; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Middle Aged; Mobility Limitation; Postural Balance; Prospective Studies; Singapore; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Lowering homocysteine levels may prevent cardiovascular impairments? Possible therapeutic behaviors.
Topics: Acetylcysteine; Aspirin; Blood Vessels; Cardiovascular Diseases; Clopidogrel; Diuretics; Fatty Acids, Omega-3; Folic Acid; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Platelet Aggregation Inhibitors; S-Adenosylmethionine; Ticlopidine; Vitamin B 12; Vitamin B 6 | 2012 |
Gender and age influence blood folate, vitamin B12, vitamin B6, and homocysteine levels in European adolescents: the Helena Study.
Topics: Adolescent; Age Factors; Child; Cross-Sectional Studies; Europe; Female; Folic Acid; Homocysteine; Humans; Male; Nutritional Status; Reference Values; Sex Factors; Vitamin B 12; Vitamin B 6 | 2012 |
Total blood mercury and rubella antibody concentrations in US children aged 6-11 years, NHANES 2003-2004.
Topics: Antibodies, Viral; Child; Cross-Sectional Studies; Environmental Pollutants; Female; Folic Acid; Homocysteine; Humans; Immunoglobulin G; Linear Models; Male; Measles; Mercury; Methylmalonic Acid; Nutrition Surveys; United States; Vitamin B 12 | 2013 |
Combined cobalamin and iron deficiency anemia: a diagnostic approach using a model based on age and homocysteine assessment.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anemia, Iron-Deficiency; Case-Control Studies; Decision Support Techniques; Diagnostic Techniques and Procedures; Female; Hematology; Homocysteine; Humans; Male; Middle Aged; Regression Analysis; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
[Biological markers for the status of vitamins B12 and D: the importance of some analytical aspects in relation to clinical interpretation of results].
Topics: Biomarkers; Homocysteine; Humans; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D; Vitamin D Deficiency | 2012 |
The effects of normalizing hyperhomocysteinemia on clinical and operative outcomes in patients with critical limb ischemia.
Topics: Aged; Aged, 80 and over; Amputation, Surgical; Biomarkers; Chi-Square Distribution; Critical Illness; Disease-Free Survival; Drug Therapy, Combination; Endovascular Procedures; Female; Folic Acid; Hemodynamics; Homocysteine; Humans; Hyperhomocysteinemia; Ischemia; Kaplan-Meier Estimate; Limb Salvage; Logistic Models; Lower Extremity; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Risk Factors; Time Factors; Treatment Outcome; Vascular Patency; Vitamin B 12; Vitamin B Complex | 2012 |
Cognitive function in an elderly population: interaction between vitamin B12 status, depression, and apolipoprotein E ε4: the Hordaland Homocysteine Study.
Topics: Aged; Apolipoprotein E4; Cognition; Cognition Disorders; Cross-Sectional Studies; Depression; Female; Homocysteine; Humans; Linear Models; Male; Methylmalonic Acid; Neuropsychological Tests; Norway; Regression Analysis; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Association of homocysteine levels with blood lead levels and micronutrients in the US general population.
Topics: Adult; Aged; Female; Folic Acid; Homocysteine; Humans; Lead; Male; Micronutrients; Middle Aged; Nutrition Surveys; Odds Ratio; United States; Vitamin B 12; Vitamin B 6 | 2012 |
Effect of carbamazepine therapy on homocysteine, vitamin B12 and folic acid levels in children with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Neurocysticercosis; Prospective Studies; Vitamin B 12 | 2013 |
Systemic folate status, rectal mucosal folate concentration and dietary intake in patients at differential risk of bowel cancer (The FAB2 Study).
Topics: Cohort Studies; Colorectal Neoplasms; Diet; Erythrocytes; Female; Folic Acid; Glutathione Reductase; Homocysteine; Humans; Intestinal Mucosa; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutrition Assessment; Nutritional Status; Risk Factors; Surveys and Questionnaires; Tetrahydrofolates; Vitamin B 12 | 2013 |
Low folate and vitamin B12 nourishment is common in Omani children with newly diagnosed autism.
Topics: Autistic Disorder; Case-Control Studies; Child, Preschool; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Nutrition Assessment; Nutritional Status; Odds Ratio; Oman; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Significant reduction of serum homocysteine level and oral symptoms after different vitamin-supplement treatments in patients with burning mouth syndrome.
Topics: Adult; Aged; Aged, 80 and over; Anemia, Iron-Deficiency; Burning Mouth Syndrome; Calcium; Female; Ferric Compounds; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Hematinics; Hemoglobins; Homocysteine; Humans; Iron; Male; Middle Aged; Niacinamide; Pantothenic Acid; Remission Induction; Riboflavin; Thiamine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B Complex | 2013 |
[Correlation between plasma concentrations of homocysteine and diabetic polyneuropathy evaluated with the Semmes-Weinstein monofilament test in patients with type 2 diabetes mellitus].
Topics: Age Factors; Aged; Alcohol Drinking; Cardiovascular Diseases; Case-Control Studies; Creatinine; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Progression; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Hypesthesia; Hypoglycemic Agents; Hypolipidemic Agents; Male; Middle Aged; Overweight; Physical Examination; Risk Factors; Severity of Illness Index; Smoking; Vitamin B 12 | 2013 |
Associations between elevated homocysteine, cognitive impairment, and reduced white matter volume in healthy old adults.
Topics: Age Factors; Aged; Asian People; Brain; Cardiovascular Diseases; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Linear Models; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated; Neuropsychological Tests; Organ Size; Singapore; Vitamin B 12 | 2013 |
Vitamin B(12) intake and status in early pregnancy among urban South Indian women.
Topics: Adolescent; Adult; Anthropometry; Cross-Sectional Studies; Diet; Dietary Supplements; Erythrocytes; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; India; Methylmalonic Acid; Nutritional Status; Parity; Pregnancy; Prevalence; Socioeconomic Factors; Surveys and Questionnaires; Urban Population; Vitamin B 12; Vitamin B 12 Deficiency; White People; Young Adult | 2013 |
Reliability of selected antioxidants and compounds involved in one-carbon metabolism in two Dutch cohorts.
Topics: Adult; Aged; Antioxidants; Ascorbic Acid; Biomarkers; Carbon; Carotenoids; Cohort Studies; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Netherlands; Nutritional Status; Tocopherols; Vitamin A; Vitamin B 12; Vitamin B 6; Young Adult | 2013 |
Homocysteine plasma levels in patients treated with antiepileptic drugs depend on folate and vitamin B12 serum levels, but not on genetic variants of homocysteine metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Anticonvulsants; Cystathionine beta-Synthase; Epilepsy; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Variation; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Tetrahydrofolate Dehydrogenase; Transcobalamins; Vitamin B 12 | 2013 |
Association between hypocobalaminaemia and hyperhomocysteinaemia in dogs.
Topics: Animals; Breeding; Dog Diseases; Dogs; Female; Folic Acid; Gastrointestinal Diseases; Homocysteine; Hyperhomocysteinemia; Male; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Detection of vitamin B12 deficiency in alcohol abuse.
Topics: Alcohol Abstinence; Alcoholism; Homocysteine; Humans; Methylmalonic Acid; Optic Atrophy, Hereditary, Leber; Smoking; Vision Disorders; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Homocysteine levels in patients with primary and secondary Raynaud's phenomenon. Its association with microangiopathy severity.
Topics: Adult; Aged; Capillaries; Female; Folic Acid; Homocysteine; Humans; Microcirculation; Middle Aged; Raynaud Disease; Vitamin B 12; Young Adult | 2014 |
Higher plasma homocysteine is associated with increased risk of developing colorectal polyps.
Topics: Case-Control Studies; Colonic Polyps; Confidence Intervals; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Pyridoxal Phosphate; Risk Factors; Taiwan; Vitamin B 12; Vitamin B Complex | 2013 |
[Association of serum homocysteine and methionine levels with cognition and functioning in bipolar disorder].
Topics: Bipolar Disorder; Case-Control Studies; Cognition; Folic Acid; Homocysteine; Humans; Methionine; Psychiatric Status Rating Scales; Severity of Illness Index; Vitamin B 12 | 2013 |
Vitamin B12 deficiency and hyperhomocysteinemia as correlates of cardiovascular risk factors in Indian subjects with coronary artery disease.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Coronary Artery Disease; Dyslipidemias; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Serum folate and vitamin B12 concentrations in relation to prostate cancer risk--a Norwegian population-based nested case-control study of 3000 cases and 3000 controls within the JANUS cohort.
Topics: Adult; Aged; Case-Control Studies; Confidence Intervals; Folic Acid; Genotype; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Norway; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Genetic; Population Surveillance; Prospective Studies; Prostatic Neoplasms; Risk Factors; Socioeconomic Factors; Vitamin B 12 | 2013 |
Advanced age as a risk factor for folate-associated functional cobalamin deficiency.
Topics: Aged; Aged, 80 and over; Causality; Cognition Disorders; Comorbidity; Female; Folic Acid; Geriatric Assessment; Homocysteine; Humans; Male; Methylmalonic Acid; Risk Factors; Severity of Illness Index; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Maternal first-trimester dietary intake and childhood blood pressure: the Generation R Study.
Topics: Blood Pressure; Child; Cohort Studies; Diet; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hypertension; Male; Maternal Nutritional Physiological Phenomena; Micronutrients; Netherlands; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Vitamin B 12 | 2013 |
The distribution of serum folate concentration and red blood cell indices in alcoholics.
Topics: Adult; Aged; Alcohol Drinking; Alcoholics; Alcoholism; Case-Control Studies; Erythrocytes; Ethanol; Folic Acid; Folic Acid Deficiency; Hematocrit; Hemoglobins; Homocysteine; Humans; Male; Middle Aged; Poland; Vitamin B 12; Young Adult | 2013 |
Plasmatic higher levels of homocysteine in non-alcoholic fatty liver disease (NAFLD).
Topics: Adult; Biomarkers; Brazil; Cholesterol; Chronic Disease; Fatty Liver; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Leukocytes, Mononuclear; Liver; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Non-alcoholic Fatty Liver Disease; Polymorphism, Genetic; Triglycerides; Vitamin B 12 | 2013 |
Glutathione metabolism in cobalamin deficiency type C (cblC).
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Carrier Proteins; Case-Control Studies; Child; Child, Preschool; Cysteine; Disease Progression; Female; Glutathione; Homocysteine; Homocystinuria; Humans; Infant; Lymphocytes; Male; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Oxygen; Reactive Oxygen Species; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Vitamin B12 deficiency: a treatable cause of developmental delay in infancy.
Topics: Atrophy; Developmental Disabilities; Female; Fever; Homocysteine; Humans; Infant; Muscle Hypotonia; Neuroimaging; Seizures; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult | 2013 |
Homocysteine and MTHFR C677T polymorphism in children and adolescents with psychotic and mood disorders.
Topics: Adolescent; Base Sequence; Case-Control Studies; Child; DNA Primers; Female; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mood Disorders; Polymerase Chain Reaction; Polymorphism, Genetic; Schizophrenia; Vitamin B 12 | 2014 |
Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine.
Topics: Adult; Betaine; Choline; Dietary Supplements; Fasting; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Nutritional Status; Pregnancy; Sarcosine; Spain; Vitamin B 12 | 2013 |
MTHFR C677T polymorphism, folate, vitamin B12 and homocysteine in recurrent pregnancy losses: a case control study among North Indian women.
Topics: Abortion, Habitual; Adolescent; Adult; Amino Acid Substitution; Case-Control Studies; Female; Folic Acid; Gene Frequency; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; India; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2013 |
Homocysteine, antioxidant micronutrients and late onset dementia.
Topics: Aged; Aged, 80 and over; Antioxidants; Body Mass Index; Cognition; Dementia; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Micronutrients; Nutrition Assessment; Proportional Hazards Models; Risk Factors; Socioeconomic Factors; Surveys and Questionnaires; Vitamin B 12 | 2014 |
Homocysteine, folate, vitamin B-12, and 10-y incidence of age-related macular degeneration.
Topics: Aged; Animals; Female; Fishes; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Incidence; Leukocyte Count; Macular Degeneration; Male; Middle Aged; Prospective Studies; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Impact of gluten-free diet on cardiovascular risk factors. A retrospective analysis in a large cohort of coeliac patients.
Topics: Adult; Body Mass Index; Cardiovascular Diseases; Celiac Disease; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diet, Gluten-Free; Female; Folic Acid; gamma-Glutamyltransferase; Homocysteine; Humans; Insulin Resistance; Male; Middle Aged; Retrospective Studies; Risk Factors; Triglycerides; Vitamin B 12; Young Adult | 2013 |
Neonatal folate, homocysteine, vitamin B12 levels and methylenetetrahydrofolate reductase variants in childhood asthma and eczema.
Topics: Asthma; Biomarkers; Child; Child, Preschool; Dermatitis, Atopic; Female; Fetal Blood; Folic Acid; Follow-Up Studies; Genetic Markers; Genotype; Homocysteine; Humans; Infant; Infant, Newborn; Linear Models; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Prospective Studies; Surveys and Questionnaires; Vitamin B 12 | 2013 |
Plasma folate, but not homocysteine, is associated with Apolipoprotein A1 levels in a non-fortified population.
Topics: Adult; Apolipoprotein A-I; Apolipoproteins B; Female; Folic Acid; Genetic Association Studies; Genetics, Population; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Infarction; Polymorphism, Genetic; Risk Factors; Vitamin B 12 | 2013 |
Maternal first-trimester diet and childhood bone mass: the Generation R Study.
Topics: Absorptiometry, Photon; Adult; Bone Density; Calcium, Dietary; Child; Diet; Female; Folic Acid; Homocysteine; Humans; Life Style; Magnesium; Male; Maternal Nutritional Physiological Phenomena; Phosphorus, Dietary; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Socioeconomic Factors; Surveys and Questionnaires; Vitamin B 12 | 2013 |
Should we be taking B vitamins to prevent age-related macular degeneration? Not yet, but worth doing more research.
Topics: Animals; Female; Folic Acid; Homocysteine; Humans; Macular Degeneration; Male; Vitamin B 12 | 2013 |
Homocysteine, vitamin B12 and folate levels in Iranian patients with Multiple Sclerosis: a case control study.
Topics: Adult; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Interferon-beta; Iran; Male; Multiple Sclerosis, Chronic Progressive; Prospective Studies; Vitamin B 12 | 2013 |
Are vitamin B(12) levels really increased in women delivering preterm?
Topics: Female; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Pregnancy; Premature Birth; Vitamin B 12; Vitamin B Complex | 2013 |
A prospective study of maternal fatty acids, micronutrients and homocysteine and their association with birth outcome.
Topics: Adult; Birth Weight; Chromatography, Gas; Fatty Acids; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; India; Longitudinal Studies; Luminescent Measurements; Micronutrients; Mothers; Pregnancy; Prospective Studies; Vitamin B 12; Young Adult | 2015 |
Effect of multivitamins on plasma homocysteine in patients with the 5,10 methylenetetrahydrofolate reductase C677T homozygous state.
Topics: Adult; Female; Folic Acid; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Vitamin B 12; Vitamins | 2013 |
Problems related to the diagnosis of vitamin B12 deficiency optic neuropathy.
Topics: False Positive Reactions; Homocysteine; Humans; Methylmalonic Acid; Optic Nerve Diseases; Predictive Value of Tests; Reproducibility of Results; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Neuropathy and levodopa in Parkinson's disease: evidence from a multicenter study.
Topics: Aged; Antiparkinson Agents; Female; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Logistic Models; Male; Middle Aged; Neural Conduction; Parkinson Disease; Peripheral Nervous System Diseases; Prevalence; Risk; Vitamin B 12 | 2013 |
Early biochemical and hematological response to intramuscular cyanocobalamin therapy in vitamin B(12)-deficient patients.
Topics: Aged; Chromatography, High Pressure Liquid; Cysteine; Erythrocyte Indices; Female; Folic Acid; Homocysteine; Humans; Injections, Intramuscular; Male; Methionine; Methylmalonic Acid; Middle Aged; Statistics, Nonparametric; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Prenatal omega 3 fatty acid supplementation to a micronutrient imbalanced diet protects brain neurotrophins in both the cortex and hippocampus in the adult rat offspring.
Topics: Animal Nutritional Physiological Phenomena; Animals; Brain; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Cognition; Diet; Dietary Supplements; Fatty Acids, Omega-3; Female; Folic Acid; Folic Acid Deficiency; Hippocampus; Homocysteine; Maze Learning; Micronutrients; Nerve Growth Factor; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Plasma homocysteine concentrations in the acute phase after central retinal vein occlusion in a Chinese population.
Topics: Acute Disease; Aged; Asian People; Cardiovascular Diseases; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2013 |
Influence of maternal vitamin B12 and folate on growth and insulin resistance in the offspring.
Topics: Adiposity; Adolescent; Adult; Animals; Body Weight; Carbon; Cardiovascular Diseases; Child; Chronic Disease; Diabetes Mellitus; Female; Folic Acid; Folic Acid Deficiency; Growth; Homocysteine; Humans; India; Infant; Infant, Newborn; Insulin Resistance; Maternal Nutritional Physiological Phenomena; Neural Tube Defects; Nutritional Status; Pregnancy; Pregnancy Complications; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2013 |
Determinants of plasma homocysteine in coal miners.
Topics: Adult; Body Mass Index; Case-Control Studies; Coal Mining; Cystatin C; Folic Acid; Homocysteine; Humans; Luminescent Measurements; Male; Middle Aged; Occupational Exposure; Risk Factors; Urea; Vitamin B 12 | 2013 |
Homocysteine levels and dementia risk in Yoruba and African Americans.
Topics: Aged; Aged, 80 and over; Black or African American; Black People; Dementia; Female; Folic Acid; Homocysteine; Humans; Incidence; Indiana; Longitudinal Studies; Male; Neuropsychological Tests; Nigeria; Vitamin B 12 | 2013 |
Impact of hyperhomocysteinemia on breast cancer initiation and progression: epigenetic perspective.
Topics: BRCA1 Protein; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Homocysteine; Humans; Hyperhomocysteinemia; MCF-7 Cells; Membrane Proteins; Microtubule-Associated Proteins; Proto-Oncogene Proteins; Transcriptome; Tumor Suppressor Proteins; Vitamin B 12 | 2014 |
Low birthweight (LBW) and neonatal hyperbilirubinemia (NNH) in an Indian cohort: association of homocysteine, its metabolic pathway genes and micronutrients as risk factors.
Topics: Cohort Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperbilirubinemia, Neonatal; Incidence; India; Infant, Low Birth Weight; Infant, Newborn; Male; Micronutrients; Pregnancy; Risk Factors; Vitamin B 12 | 2013 |
Dyslipidemia in pediatric systemic lupus erythematosus: the relationship with disease activity and plasma homocysteine and cysteine concentrations.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Child; Cholesterol, HDL; Cholesterol, LDL; Cross-Sectional Studies; Cysteine; Dyslipidemias; Energy Intake; Female; Folic Acid; Homocysteine; Humans; Lupus Erythematosus, Systemic; Multivariate Analysis; Nutritional Status; Puberty; Risk Factors; Triglycerides; Vitamin B 12; Waist Circumference; Young Adult | 2013 |
Relationship between metformin use, vitamin B12 deficiency, hyperhomocysteinemia and vascular complications in patients with type 2 diabetes.
Topics: Aged; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Retinopathy; Dietary Supplements; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Japan; Male; Metformin; Middle Aged; Prevalence; Risk Factors; Severity of Illness Index; Stroke; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Nutrients related to the incidence of early and late age-related macular degeneration.
Topics: Animals; Female; Folic Acid; Homocysteine; Humans; Macular Degeneration; Male; Vitamin B 12 | 2013 |
Role of serum holotranscobalamin (holoTC) in the diagnosis of patients with low serum cobalamin. Comparison with methylmalonic acid and homocysteine.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2014 |
Prevalence and features of peripheral neuropathy in Parkinson's disease patients under different therapeutic regimens.
Topics: Aged; Antiparkinson Agents; Cross-Sectional Studies; Electromyography; Female; Folic Acid; Homocysteine; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Peripheral Nervous System Diseases; Prevalence; Vitamin B 12 | 2014 |
Oral manifestations and blood profile in patients with thalassemia trait.
Topics: Adult; Aged; Aged, 80 and over; Atrophy; Case-Control Studies; Erythrocyte Count; Erythrocyte Indices; Female; Folic Acid; Glossitis; Hemoglobins; Homocysteine; Humans; Hypesthesia; Iron; Male; Middle Aged; Mouth Mucosa; Thalassemia; Tongue; Varicose Veins; Vitamin B 12; Xerostomia; Young Adult | 2013 |
Association between maternal folate concentrations during pregnancy and insulin resistance in Indian children.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Insulin Resistance; Pregnancy; Vitamin B 12; Young Adult | 2014 |
Reply to Kawada.
Topics: Animals; Female; Folic Acid; Homocysteine; Humans; Macular Degeneration; Male; Vitamin B 12 | 2013 |
Role of plasma homocysteine levels and MTHFR polymorphisms on IQ scores in children and young adults with epilepsy treated with antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Child; Cognition Disorders; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Intelligence Tests; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neuropsychological Tests; Polymorphism, Genetic; Statistics, Nonparametric; Vitamin B 12; Young Adult | 2013 |
Hyperhomocysteinemia in bipolar depression: clinical and biochemical correlates.
Topics: Adult; Aged; Biomarkers; Bipolar Disorder; E-Selectin; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intercellular Adhesion Molecule-1; Male; Middle Aged; Vitamin B 12; Young Adult | 2013 |
The MTHFR 677T allele may influence the severity and biochemical risk factors of Alzheimer's disease in an Egyptian population.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cholesterol; Egypt; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12 | 2013 |
Vitamin B12 deficiency in relation to functional disabilities.
Topics: Activities of Daily Living; Aged; Biomarkers; Cognition; Disability Evaluation; Disabled Persons; Female; Geriatric Assessment; Homocysteine; Humans; Male; Methylmalonic Acid; Odds Ratio; Peripheral Nervous System Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Interactions between plasma concentrations of folate and markers of vitamin B(12) status with cognitive performance in elderly people not exposed to folic acid fortification: the Hordaland Health Study.
Topics: Aged; Biomarkers; Cognition Disorders; Cross-Sectional Studies; Diet; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methylmalonic Acid; Norway; Nutritional Status; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Plasma homocysteine, folic acid, and vitamin B₁₂ levels in patients with pseudoexfoliation syndrome, pseudoexfoliation glaucoma, and normotensive glaucoma.
Topics: Aged; Exfoliation Syndrome; Female; Folic Acid; Glaucoma; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12 | 2013 |
Homocysteine in dogs with systemic inflammatory response syndrome.
Topics: Animals; Case-Control Studies; Dog Diseases; Dogs; Female; Folic Acid; Homocysteine; Male; Sepsis; Systemic Inflammatory Response Syndrome; Vitamin B 12 | 2013 |
Homocysteine and serotonin: association with postpartum depression.
Topics: Adult; Depression, Postpartum; Female; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Serotonin; Vitamin B 12 | 2013 |
[Prevention of ischemic stroke by homocysteine-lowering therapy: lack of consistent evidence].
Topics: Down-Regulation; Homocysteine; Humans; Recurrence; Stroke; Vitamin B 12; Vitamin B 6 | 2013 |
Serum and red blood cell folate testing for folate deficiency: new features?
Topics: Erythrocyte Indices; Erythrocytes; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Retrospective Studies; Vitamin B 12 | 2014 |
Smokeless tobacco use: a risk factor for hyperhomocysteinemia in a Pakistani population.
Topics: Adolescent; Adult; Cities; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Income; Male; Middle Aged; Pakistan; Pyridoxal Phosphate; Risk Factors; Tobacco, Smokeless; Vitamin B 12; Young Adult | 2013 |
Systemic chemotherapy interferes in homocysteine metabolism in breast cancer patients.
Topics: Antineoplastic Agents; Blood Platelets; Breast Neoplasms; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Vitamin B 12 | 2014 |
Imbalance of folic acid and vitamin B12 is associated with birth outcome: an Indian pregnant women study.
Topics: Anthropometry; Birth Weight; Body Size; Dietary Supplements; Female; Folic Acid; Head; Hematinics; Homocysteine; Humans; India; Nutritional Requirements; Pregnancy; Pregnancy Complications; Thorax; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Young Adult | 2014 |
Homocysteine metabolism in children with idiopathic nephrotic syndrome.
Topics: Case-Control Studies; Child; Cholesterol; Cysteine; Demography; Female; Folic Acid; Homocysteine; Humans; Male; Nephrotic Syndrome; Proteinuria; Remission Induction; Serum Albumin; Vitamin B 12 | 2014 |
MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification.
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Denmark; Dyslipidemias; Female; Folic Acid; Follow-Up Studies; Genotype; Genotyping Techniques; Homocysteine; Humans; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Stroke; Triglycerides; Vitamin B 12; Young Adult | 2014 |
Water-soluble vitamin deficiencies in complicated peptic ulcer patients soon after ulcer onset in Japan.
Topics: Adult; Aged; Aged, 80 and over; Ascorbic Acid; Cohort Studies; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Japan; Male; Middle Aged; Peptic Ulcer; Prospective Studies; Riboflavin; Thiamine; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2013 |
C677T methylenetetrahydrofolate reductase and plasma homocysteine levels among Thai vegans and omnivores.
Topics: Adult; Diet, Vegetarian; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Vitamin B 12 | 2013 |
Gene promoter methylation in colorectal cancer and healthy adjacent mucosa specimens: correlation with physiological and pathological characteristics, and with biomarkers of one-carbon metabolism.
Topics: Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Colon; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Intestinal Mucosa; Male; Metabolic Networks and Pathways; Middle Aged; Polymorphism, Genetic; Promoter Regions, Genetic; Rectum; Vitamin B 12 | 2014 |
Prevalence and predictors of anemia in a population of North Indian children.
Topics: Anemia; Anemia, Iron-Deficiency; Biomarkers; Body Height; Child, Preschool; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Income; India; Infant; Iron; Iron Deficiencies; Male; Nutritional Status; Prevalence; Receptors, Transferrin; Vitamin B 12 | 2014 |
Folate and cobalamin modify associations between S-adenosylmethionine and methylated arsenic metabolites in arsenic-exposed Bangladeshi adults.
Topics: Adult; Aged; Arsenic; Arsenic Poisoning; Arsenicals; Bangladesh; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2014 |
Hemoglobin, iron, and vitamin B12 deficiencies and high blood homocysteine levels in patients with anti-thyroid autoantibodies.
Topics: Adult; Aged; Aged, 80 and over; Autoantibodies; Biomarkers; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Hemoglobins; Homocysteine; Humans; Hyperthyroidism; Hypothyroidism; Iron; Iron Deficiencies; Male; Middle Aged; Parietal Cells, Gastric; Thyroiditis, Autoimmune; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Biomarkers of one-carbon metabolism are associated with biomarkers of inflammation in women.
Topics: Aged; Biomarkers; C-Reactive Protein; Carbon; Chronic Disease; Cross-Sectional Studies; Cysteine; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Inflammation; Linear Models; Middle Aged; Nutritional Status; Risk Factors; Serum Amyloid A Protein; Vitamin B 12; Vitamin B 6 | 2014 |
Hyperhomocysteinemia is a risk factor for Alzheimer's disease in an Algerian population.
Topics: Aged; Aged, 80 and over; Algeria; Alzheimer Disease; Case-Control Studies; Cholesterol; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Risk Factors; Thyrotropin; Uric Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2014 |
Elevated homocysteine level in first-episode schizophrenia patients--the relevance of family history of schizophrenia and lifetime diagnosis of cannabis abuse.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Lipoproteins, HDL; Male; Marijuana Abuse; Schizophrenia; Vitamin B 12; Young Adult | 2014 |
Effect of vitamin B deprivation during pregnancy and lactation on homocysteine metabolism and related metabolites in brain and plasma of mice offspring.
Topics: Animals; Brain; Female; Folic Acid; Homocysteine; Lactation; Male; Mice; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamin B Deficiency | 2014 |
High-dose compared with low-dose vitamin B-12 supplement use is not associated with higher vitamin B-12 status in children, adolescents, and older adults.
Topics: Adolescent; Adult; Aged; Canada; Child; Cross-Sectional Studies; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12; Young Adult | 2014 |
[Posterior-predominant leukoencephalopathy which was caused by methylenetetrahydrofolate reductase deficiency and successfully treated with folic acid].
Topics: Adult; Biomarkers; Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Leukoencephalopathies; Magnetic Resonance Imaging; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Mutation, Missense; Polymorphism, Single Nucleotide; Psychotic Disorders; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2014 |
[Borderline vitamin B 12 level. Is it clinically relevant?].
Topics: Administration, Oral; Homocysteine; Humans; Injections, Intramuscular; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Homocysteine-lowering therapy and risk of recurrent stroke, myocardial infarction and death: the impact of age in the VISP trial.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Female; Homocysteine; Humans; Male; Middle Aged; Myocardial Infarction; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Stroke; Vitamin B 12; Vitamins | 2014 |
Vitamin B12 levels are not affected by radioiodine ablation of the thyroid.
Topics: Adenoma; Adult; Aged; Carcinoma, Papillary, Follicular; Case-Control Studies; Cross-Sectional Studies; Female; Goiter, Nodular; Graves Disease; Homocysteine; Humans; Iodine Radioisotopes; Male; Middle Aged; Thyroid Neoplasms; Vitamin B 12 | 2014 |
Plasma vitamin B12, methylmalonic acid and heart rate variability in healthy young Indian adults.
Topics: Adult; Heart Rate; Homocysteine; Humans; India; Male; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2013 |
Serum one-carbon metabolites and risk of cervical cancer.
Topics: Adult; Aged; DNA-Binding Proteins; Down-Regulation; Female; Folic Acid; Heterogeneous-Nuclear Ribonucleoproteins; Homocysteine; Humans; Middle Aged; Oncogene Proteins, Viral; Papillomavirus Infections; Repressor Proteins; Risk Factors; RNA-Binding Proteins; RNA, Messenger; Squamous Intraepithelial Lesions of the Cervix; Uterine Cervical Neoplasms; Viral Proteins; Vitamin B 12 | 2014 |
[Correlation between serum levels of homocysteine and folate and cognitive dysfunction in first-episode schizophrenics].
Topics: Adolescent; Adult; Case-Control Studies; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Schizophrenia; Vitamin B 12; Young Adult | 2014 |
Closing the gaps in pediatric reference intervals: an update on the CALIPER project.
Topics: Adolescent; Biomarkers; Canada; Child; Child, Preschool; Female; Ferritins; Homocysteine; Hormones; Humans; Infant; Infant, Newborn; Male; Reference Values; Vitamin B 12; Young Adult | 2014 |
Vascular function and risk factors in children with epilepsy: associations with sodium valproate and carbamazepine.
Topics: Adolescent; Anticonvulsants; Aorta; Blood Glucose; Brachial Artery; Carbamazepine; Carotid Arteries; Cholesterol; Cholesterol, HDL; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Phosphoric Monoester Hydrolases; Risk Factors; Ultrasonography; Valproic Acid; Vitamin B 12 | 2014 |
Lead exposure, B vitamins, and plasma homocysteine in men 55 years of age and older: the VA normative aging study.
Topics: Aged; Aged, 80 and over; Bone and Bones; Cohort Studies; Cross-Sectional Studies; Diet; Environmental Exposure; Environmental Pollutants; Folic Acid; Homocysteine; Humans; Lead; Lead Poisoning; Male; Middle Aged; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2014 |
Plasma homocysteine concentrations in acute and convalescent changes of central retinal vein occlusion in a Chinese population.
Topics: Aged; Biomarkers; China; DNA; Electroretinography; Female; Folic Acid; Follow-Up Studies; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Methylenetetrahydrofolate Reductase (NADPH2); Microscopy, Acoustic; Middle Aged; Ophthalmoscopy; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Prognosis; Retinal Vein Occlusion; Retrospective Studies; Risk Factors; Time Factors; Tomography, Optical Coherence; Vitamin B 12 | 2014 |
Vitamin B12 deficiency in Jordan: a population-based study.
Topics: Adult; Aged; Aged, 80 and over; Female; Folic Acid Deficiency; Homocysteine; Humans; Jordan; Logistic Models; Male; Middle Aged; Multivariate Analysis; Nutritional Status; Pilot Projects; Prevalence; Socioeconomic Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Young Adult | 2014 |
Hyperhomocysteinemia and assessment of its associated factors in renal transplant recipients: a single-center study in northern Iran.
Topics: Adult; Biomarkers; Blood Urea Nitrogen; Chi-Square Distribution; Creatinine; Cross-Sectional Studies; Cyclosporine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Iran; Kidney Failure, Chronic; Kidney Transplantation; Linear Models; Male; Middle Aged; Multivariate Analysis; Prevalence; Risk Factors; Time Factors; Vitamin B 12 | 2014 |
Domain specific changes in cognition at high altitude and its correlation with hyperhomocysteinemia.
Topics: Acclimatization; Adult; Altitude; Cognition; Cognitive Dysfunction; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Neuropsychological Tests; Vitamin B 12 | 2014 |
Associations between medication use and homocysteine levels in an older population, and potential mediation by vitamin B12 and folate: data from the B-PROOF Study.
Topics: Aged; Diuretics; Female; Folic Acid; Health Services for the Aged; Homocysteine; Humans; Male; Metformin; Netherlands; Osteoporosis; Population Surveillance; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Homocysteine Levels and Oxidative Stress Parameters in Patients With Adult ADHD.
Topics: Adult; Antioxidants; Attention Deficit Disorder with Hyperactivity; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Oxidants; Oxidative Stress; Vitamin B 12 | 2017 |
Vitamin status as a determinant of serum homocysteine concentration in type 2 diabetic retinopathy.
Topics: Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Prevalence; Regression Analysis; Risk Factors; Vitamin B 12; Vitamins | 2014 |
Homocysteine levels and bad obstetric outcome among female operating room personnel occupationally exposed to nitrous oxide.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Nitrous Oxide; Occupational Exposure; Operating Room Technicians; Pregnancy; Pregnancy Outcome; Reproductive History; Vitamin B 12 | 2014 |
Maternal homocysteine in pregnancy and offspring birthweight: epidemiological associations and Mendelian randomization analysis.
Topics: Adult; Biomarkers; Birth Weight; Cohort Studies; Female; Fetal Development; Folic Acid; Genotype; Gestational Age; Homocysteine; Humans; India; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Prenatal Exposure Delayed Effects; Vitamin B 12 | 2014 |
B12 deficiency increases with age in hospitalized patients: a study on 14,904 samples.
Topics: Adolescent; Adult; Age Distribution; Age Factors; Aged; Aged, 80 and over; Aging; Female; Follow-Up Studies; Hemoglobins; Homocysteine; Humans; Inpatients; Male; Middle Aged; Morbidity; Paris; Retrospective Studies; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2014 |
Early markers of occult megaloblastosis for low-cost detection of hyperhomocysteinemia in patients with ischaemic stroke: preventive approach for primary health care.
Topics: Anemia, Megaloblastic; Biomarkers; Brain Ischemia; Early Diagnosis; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neutrophils; Primary Health Care; Stroke; Vitamin B 12 | 2014 |
Homocysteine, cysteine, folate and vitamin B₁₂ status in type 2 diabetic patients with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Biomarkers; Chromatography, High Pressure Liquid; Cysteine; Diabetes Mellitus, Type 2; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Male; Renal Insufficiency, Chronic; Vitamin B 12 | 2015 |
The roles of methylenetetrahydrofolate reductase 677C>T and 1298A>C polymorphisms in moyamoya disease patients.
Topics: Adolescent; Adult; Case-Control Studies; Child; Child, Preschool; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Moyamoya Disease; Nitric Oxide; Polymorphism, Single Nucleotide; Republic of Korea; Vitamin B 12; Young Adult | 2014 |
Serum nutritional biomarkers and their associations with sleep among US adults in recent national surveys.
Topics: Adult; Aged; Aged, 80 and over; Ascorbic Acid; Carotenoids; Dyssomnias; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Models, Statistical; Nutrition Surveys; Nutritional Status; Sleep; United States; Vitamin A; Vitamin B 12; Vitamin D; Vitamin E | 2014 |
Plasma total homocysteine level in association with folate, pyridoxine, and cobalamin status among Iranian primary breast cancer patients.
Topics: Adult; Aged; Biomarkers; Body Mass Index; Breast Neoplasms; Fasting; Female; Folic Acid; Homocysteine; Humans; Iran; Linear Models; Logistic Models; Middle Aged; Multivariate Analysis; Nutrition Assessment; Nutritional Status; Prospective Studies; Pyridoxal Phosphate; Pyridoxine; Surveys and Questionnaires; Vitamin B 12; White People | 2014 |
MTHFR polymorphisms and serum cobalamin affect plasma homocysteine concentrations differentially in females and males.
Topics: Adult; Female; Gene Frequency; Genetic Association Studies; Haplotypes; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Sex Characteristics; Spain; Vitamin B 12 | 2014 |
Increase in the risk of ST elevation myocardial infarction is associated with homocysteine level.
Topics: Adult; Biomarkers; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Myocardial Infarction; Risk Assessment; Risk Factors; Vitamin B 12 | 2014 |
Maternal vitamin B12 deficiency detected in expanded newborn screening.
Topics: Carnitine; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Neonatal Screening; Pregnancy; Pregnancy Complications; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Nutritional status of the elderly in rural North China: a cross-sectional study.
Topics: Aged; Aged, 80 and over; Body Mass Index; China; Cholesterol; Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutrition Surveys; Nutritional Status; Obesity; Prevalence; Rural Health; Rural Population; Thinness; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Effects of second-generation antipsychotics on selected markers of one-carbon metabolism and metabolic syndrome components in first-episode schizophrenia patients.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Body Mass Index; Carbon; Cholesterol; Female; Folic Acid; Homocysteine; Humans; Lipid Metabolism; Male; Metabolic Syndrome; Olanzapine; Risperidone; Schizophrenia; Sex Factors; Triglycerides; Vitamin B 12; Young Adult | 2014 |
The changing of serum vitamin B12 and homocysteine levels after gastrectomy in patients with gastric cancer: do they associate with clinicopathological factors?
Topics: Adult; Aged; Aged, 80 and over; Female; Folic Acid; Gastrectomy; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Stomach Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Severe motor neuropathy or neuronopathy due to nitrous oxide toxicity after correction of vitamin B12 deficiency.
Topics: Homocysteine; Humans; Male; Motor Neuron Disease; Nitrous Oxide; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2015 |
Plasma homocysteine, B vitamins and bone mineral density in osteoporosis: a possible risk for bone fracture.
Topics: Body Mass Index; Bone Density; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nigeria; Osteoporosis; Osteoporotic Fractures; Risk Factors; Vitamin B 12; Vitamin B 6 | 2014 |
Reliable and powerful laboratory markers of cobalamin deficiency in the newborn: plasma and urinary methylmalonic acid.
Topics: Adult; Biomarkers; Cohort Studies; Female; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Pregnancy; Pregnancy Complications; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2016 |
Chronic maternal vitamin B12 restriction induced changes in body composition & glucose metabolism in the Wistar rat offspring are partly correctable by rehabilitation.
Topics: Animals; Animals, Newborn; Antioxidants; Blood Glucose; Body Composition; Body Weight; Catalase; Female; Glucose; Homocysteine; Insulin; Liver; Male; Malnutrition; Maternal Nutritional Physiological Phenomena; Models, Animal; Oxidative Stress; Phosphoenolpyruvate Carboxykinase (ATP); Pregnancy; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin B 12 | 2014 |
Micronutrient status in female university students: iron, zinc, copper, selenium, vitamin B12 and folate.
Topics: Adolescent; Adult; Anemia, Iron-Deficiency; Australia; Biomarkers; Body Mass Index; Copper; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Iron, Dietary; Methylmalonic Acid; Micronutrients; Prevalence; Selenium; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult; Zinc | 2014 |
Plasma homocysteine and B vitamins levels in Nigerian children with nephrotic syndrome.
Topics: Case-Control Studies; Child; Female; Folic Acid; Homocysteine; Humans; Male; Nephrotic Syndrome; Nigeria; Serum Albumin; Vitamin B 12; Vitamin B Complex | 2014 |
Serum homocysteine, vitamin B12, and folate, and the prevalence and incidence of posterior subcapsular cataract.
Topics: Aged; Biomarkers; Cataract; Cross-Sectional Studies; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Incidence; Male; Middle Aged; New South Wales; Population Surveillance; Prevalence; Retrospective Studies; Vitamin B 12 | 2014 |
Anemias due to essential nutrient deficiencies.
Topics: Anemia; Anemia, Iron-Deficiency; Dose-Response Relationship, Drug; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Iron, Dietary; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Effects of differences in serum total homocysteine, folate, and vitamin B12 on cognitive impairment in stroke patients.
Topics: Adult; Aged; Brain; Case-Control Studies; Cognition; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Stroke; Vitamin B 12 | 2014 |
Folates from metabolically engineered rice: a long-term study in rats.
Topics: Animals; Body Weight; Erythrocytes; Female; Folic Acid; Food, Fortified; Hematocrit; Homocysteine; Longitudinal Studies; Oryza; Plants, Genetically Modified; Rats, Wistar; Vitamin B 12 | 2015 |
Heterozygous carriers of classical homocystinuria tend to have higher fasting serum homocysteine concentrations than non-carriers in the presence of folate deficiency.
Topics: Aged; Cardiovascular Diseases; Case-Control Studies; Cystathionine beta-Synthase; Dietary Supplements; Fasting; Female; Folic Acid; Folic Acid Deficiency; Genotyping Techniques; Heterozygote; Homocysteine; Homocystinuria; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Prevalence; Risk Factors; Taiwan; Vitamin B 12 | 2015 |
Association between intake of B vitamins and cognitive function in elderly Koreans with cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cognition Disorders; Diet; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Republic of Korea; Vitamin B 12; Vitamin B Complex | 2014 |
Associations between Alzheimer's disease and blood homocysteine, vitamin B12, and folate: a case-control study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Chromatography, High Pressure Liquid; Cognition Disorders; Confidence Intervals; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Psychiatric Status Rating Scales; Retrospective Studies; Surveys and Questionnaires; Vitamin B 12 | 2015 |
Influence of microelement concentration on the intensity of alcohol withdrawal syndrome.
Topics: Adult; Alcohol Withdrawal Delirium; Calcitriol; Case-Control Studies; Deficiency Diseases; Ferritins; Folic Acid; Homocysteine; Humans; Iron; Magnesium; Male; Micronutrients; Middle Aged; Severity of Illness Index; Transferrin; Tretinoin; Vitamin B 12; Young Adult; Zinc | 2015 |
Significant association of deficiencies of hemoglobin, iron, folic acid, and vitamin B12 and high homocysteine level with oral lichen planus.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Hemoglobins; Homocysteine; Humans; Iron; Iron Deficiencies; Lichen Planus, Oral; Male; Middle Aged; Severity of Illness Index; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2015 |
Functional cobalamin (vitamin B12) deficiency: role of advanced age and disorders associated with increased oxidative stress.
Topics: Aged; Aged, 80 and over; Aging; Alcohol Drinking; Connecticut; Diabetes Mellitus; Dietary Supplements; Female; Homocysteine; Humans; Injections, Intramuscular; Male; Methylmalonic Acid; Neurocognitive Disorders; Oxidative Stress; Primary Health Care; Renal Insufficiency; Retrospective Studies; Risk Factors; Smoking; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Genetic and environmental factors associated with vitamin B12 status in Amazonian children.
Topics: Alleles; Body Mass Index; Body Weight; Brazil; Child; Child, Preschool; Cross-Sectional Studies; Folic Acid; Gene-Environment Interaction; Genotyping Techniques; Growth Disorders; Homocysteine; Humans; Infant; Linear Models; Nutrition Assessment; Nutritional Status; Overweight; Polymorphism, Single Nucleotide; Prevalence; Risk Factors; Socioeconomic Factors; Vitamin A; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Age dependent levels of plasma homocysteine and cognitive performance.
Topics: Adolescent; Adult; Aged; Aging; Attention; C-Reactive Protein; Cognition; Depression; Female; Folic Acid; Homocysteine; Humans; India; Interleukin-6; Male; Mental Recall; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2015 |
Plasma folate, vitamin B12, and homocysteine and cancers of the esophagus, stomach, and liver in a Chinese population.
Topics: Adult; Aged; Case-Control Studies; China; Esophageal Neoplasms; Female; Folic Acid; Homocysteine; Humans; Liver Neoplasms; Male; Middle Aged; Odds Ratio; Risk Factors; Stomach Neoplasms; Surveys and Questionnaires; Vitamin B 12 | 2015 |
Serum folate, cobalamin, homocysteine and methylmalonic acid concentrations in pigs with acute, chronic or subclinical Lawsonia intracellularis infection.
Topics: Animals; Asymptomatic Infections; Desulfovibrionaceae Infections; Folic Acid; Homocysteine; Lawsonia Bacteria; Methylmalonic Acid; Swine; Swine Diseases; Vitamin B 12 | 2015 |
The association between vitamin B12, albuminuria and reduced kidney function: an observational cohort study.
Topics: Adult; Aged; Albuminuria; Biomarkers; Cohort Studies; Female; Glomerular Filtration Rate; Homocysteine; Humans; Kidney Function Tests; Logistic Models; Male; Middle Aged; Nutrition Surveys; Predictive Value of Tests; Prognosis; Renal Insufficiency; Risk Assessment; Vitamin B 12 | 2015 |
The influence of a whole food vegan diet with Nori algae and wild mushrooms on selected blood parameters.
Topics: Agaricales; Biomarkers; Blood Chemical Analysis; Cholecalciferol; Creatinine; Diet, Vegetarian; Dietary Supplements; Ergocalciferols; Ferritins; Folic Acid; Hemoglobins; Homocysteine; Humans; Meat; Methylmalonic Acid; Nutrition Assessment; Nutritional Status; Porphyra; Prospective Studies; Recommended Dietary Allowances; Thyrotropin; Time Factors; Transcobalamins; Vitamin B 12; Zinc | 2014 |
Vitamin B12-responsive neuropathies: A case series.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antioxidants; Biotransformation; Female; Homocysteine; Humans; Injections, Intramuscular; Male; Medical Records; Methylmalonic Acid; Middle Aged; Nervous System Diseases; Nutritional Status; Oxidative Stress; Retrospective Studies; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Combined indicator of vitamin B12 status: modification for missing biomarkers and folate status and recommendations for revised cut-points.
Topics: Biomarkers; Folic Acid; Healthy Volunteers; Homocysteine; Humans; Methylmalonic Acid; Transcobalamins; Vitamin B 12 | 2015 |
Comparison of four automated serum vitamin B12 assays.
Topics: Automation; Homocysteine; Humans; Immunoassay; Methylmalonic Acid; Regression Analysis; Vitamin B 12 | 2015 |
Metabolism and gene polymorphisms of the folate pathway in Brazilian women with history of recurrent abortion.
Topics: Abortion, Habitual; Adolescent; Adult; Brazil; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Polymorphism, Genetic; Signal Transduction; Vitamin B 12; Young Adult | 2015 |
Nitrous oxide related behavioral and histopathological changes may be related to oxidative stress.
Topics: Animals; Antioxidants; Behavior, Animal; Brain; Demyelinating Diseases; Disease Models, Animal; Glutathione; Homocysteine; Hyperhomocysteinemia; Male; Motor Activity; Muscle Strength; Nitrous Oxide; Oxidative Stress; Rats, Wistar; Spinal Cord; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Folate and homocysteine levels and their association with dietary intakes in Iranian patients infected with Helicobacter pylori: a case-control study.
Topics: Case-Control Studies; Diet; Folic Acid; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Iran; Logistic Models; Vitamin B 12 | 2015 |
Formate metabolism in fetal and neonatal sheep.
Topics: Amniotic Fluid; Animals; Animals, Newborn; Female; Fetus; Folic Acid; Formates; Homocysteine; Postpartum Period; Pregnancy; Pregnancy, Animal; Sheep; Vitamin B 12 | 2015 |
Gene promoter methylation and DNA repair capacity in monozygotic twins with discordant smoking habits.
Topics: Adult; Cross-Sectional Studies; DNA Methylation; DNA Repair; Female; Folic Acid; Homocysteine; Humans; Life Style; Lymphocytes; Male; Middle Aged; Promoter Regions, Genetic; Smoking; Twins, Monozygotic; Vitamin B 12; Young Adult | 2015 |
Low maternal vitamin B12 status is associated with lower cord blood HDL cholesterol in white Caucasians living in the UK.
Topics: Adult; Blood Glucose; Body Mass Index; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Cross-Sectional Studies; Diet, Vegetarian; Female; Fetal Blood; Folic Acid; Gestational Age; Homocysteine; Humans; Insulin; Insulin Resistance; Maternal Nutritional Physiological Phenomena; Nutritional Status; Pregnancy; Risk Factors; Triglycerides; United Kingdom; Vitamin B 12; White People | 2015 |
Folate, vitamin B12 and Homocysteine status in the post-folic acid fortification era in different subgroups of the Brazilian population attended to at a public health care center.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Brazil; Carboxypeptidases; Child; Child, Preschool; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant; Lactation; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pregnancy; Prevalence; Reduced Folate Carrier Protein; Risk Factors; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2015 |
Blood profile of oral mucosal disease patients with both vitamin B12 and iron deficiencies.
Topics: Adult; Aged; Autoantibodies; Case-Control Studies; Erythrocyte Indices; Female; Folic Acid; Folic Acid Deficiency; Hemoglobins; Homocysteine; Humans; Iron; Iron Deficiencies; Male; Middle Aged; Mouth Diseases; Parietal Cells, Gastric; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Nephrotic syndrome and thrombotic microangiopathy caused by cobalamin C deficiency.
Topics: Anemia; Angiotensin-Converting Enzyme Inhibitors; Biopsy; Carrier Proteins; Child, Preschool; Homocysteine; Humans; Hydroxocobalamin; Hypertension, Renal; Kidney; Male; Nephrotic Syndrome; Oxidoreductases; Thrombotic Microangiopathies; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Effects of antiepileptic drug monotherapy on one-carbon metabolism and DNA methylation in patients with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Case-Control Studies; Cross-Sectional Studies; DNA Methylation; Epilepsy; Female; Folic Acid; Heterocyclic Compounds; Homocysteine; Humans; Lamotrigine; Long Interspersed Nucleotide Elements; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Triazines; Valproic Acid; Vitamin B 12; Young Adult | 2015 |
Apolipoprotein E genotype modulates effects of vitamin B12 and homocysteine on grey matter volume in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Apolipoprotein E4; Case-Control Studies; Female; Genotype; Gray Matter; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Republic of Korea; Vitamin B 12 | 2016 |
Serum levels of homocysteine, folate and vitamin B12 in patients with vitiligo before and after treatment with narrow band ultraviolet B phototherapy and in a group of controls.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Ultraviolet Therapy; Vitamin B 12; Vitiligo | 2015 |
Genetic modifiers of folate, vitamin B-12, and homocysteine status in a cross-sectional study of the Canadian population.
Topics: Adult; Biomarkers; Canada; Case-Control Studies; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Genotype; Genotyping Techniques; Health Surveys; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neural Tube Defects; Nutritional Status; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2015 |
Fitting homocysteine to disease models, as well as adjusting the models to the disease.
Topics: Animals; Cardiovascular Diseases; Disease Models, Animal; Folic Acid; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidative Stress; Risk Factors; Signal Transduction; Vitamin B 12 | 2015 |
Pitfalls in the diagnostic evaluation of subacute combined degeneration.
Topics: Adult; Dietary Supplements; Homocysteine; Humans; Male; Methylmalonic Acid; Subacute Combined Degeneration; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2015 |
Do all the patients with vitamin B12 deficiency have pernicious anemia?
Topics: Adult; Aged; Aged, 80 and over; Anemia, Pernicious; Autoantibodies; Case-Control Studies; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Iron; Male; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2016 |
Impact of physical activity and cardiovascular fitness on total homocysteine concentrations in European adolescents: The HELENA study.
Topics: Adipose Tissue; Adiposity; Adolescent; Body Mass Index; Cardiovascular System; Cross-Sectional Studies; Europe; Exercise; Exercise Test; Female; Folic Acid; Homocysteine; Humans; Male; Oxygen Consumption; Physical Fitness; Sex Factors; Skinfold Thickness; Vitamin B 12; White People | 2015 |
Vitamin B12 and omega-3 fatty acids together regulate lipid metabolism in Wistar rats.
Topics: Adiponectin; Animals; Blood Pressure; Cholesterol; Diet; Dietary Supplements; Fatty Acids, Omega-3; Female; Homocysteine; Lipid Metabolism; Liver; Male; Pregnancy; Prenatal Nutritional Physiological Phenomena; Rats, Wistar; RNA, Messenger; Triglycerides; Vitamin B 12 | 2015 |
Cognitive Status According to Homocysteine and B-Group Vitamins in Elderly Adults.
Topics: Aged; Aged, 80 and over; Cognition; Cognition Disorders; Comorbidity; Confidence Intervals; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Male; Odds Ratio; Prevalence; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2015 |
MTHFR 677C/T and 1298A/C mutations and non-alcoholic fatty liver disease.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Non-alcoholic Fatty Liver Disease; Vitamin B 12 | 2015 |
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Chickens; Choline; Cystathionine gamma-Lyase; Cysteine; Dietary Proteins; Folic Acid; Glycine; Homocysteine; Liver; Male; Meat; Methionine; Rats; Rats, Wistar; Riboflavin; RNA, Messenger; Sarcosine; Serine; Vitamin B 12; Vitamin B 6 | 2015 |
Gene polymorphisms as risk factors for predicting the cardiovascular manifestations in Marfan syndrome. Role of folic acid metabolism enzyme gene polymorphisms in Marfan syndrome.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Aortic Aneurysm; Aortic Dissection; Biomarkers; Case-Control Studies; Chi-Square Distribution; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Heterozygote; Homocysteine; Homozygote; Humans; Logistic Models; Male; Marfan Syndrome; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Predictive Value of Tests; Risk Factors; Severity of Illness Index; Up-Regulation; Vitamin B 12; Young Adult | 2015 |
Methylation analysis of multiple genes in blood DNA of Alzheimer's disease and healthy individuals.
Topics: 5' Untranslated Regions; Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid Precursor Protein Secretases; Apolipoprotein E4; Aspartic Acid Endopeptidases; Biomarkers; Case-Control Studies; CpG Islands; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Presenilin-1; Promoter Regions, Genetic; Sex Factors; Vitamin B 12 | 2015 |
Altered one-carbon metabolism in posttraumatic stress disorder.
Topics: Adult; Case-Control Studies; Dehydroepiandrosterone; Depression; Female; Folic Acid; Homocysteine; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Middle Aged; Pituitary-Adrenal System; Psychological Trauma; Risk Factors; Stress Disorders, Post-Traumatic; Vitamin B 12; Vitamin B 6 | 2015 |
Association of Vitamin B12 Deficiency with Homozygosity of the TT MTHFR C677T Genotype, Hyperhomocysteinemia, and Endothelial Cell Dysfunction.
Topics: Adult; Cardiovascular Diseases; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Physical Endurance; Polymorphism, Genetic; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2015 |
Metagenomic sequencing reveals altered metabolic pathways in the oral microbiota of sailors during a long sea voyage.
Topics: Biodiversity; Folic Acid; Homocysteine; Humans; Metabolic Networks and Pathways; Metagenome; Metagenomics; Microbiota; Mouth; Mouth Mucosa; RNA, Ribosomal, 16S; Vitamin B 12 | 2015 |
Vitamin B12 and folate levels in healthy Swiss senior citizens: a prospective study evaluating reference intervals and decision limits.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Biomarkers; Erythrocyte Count; Female; Folic Acid; Homocysteine; Humans; Kidney Function Tests; Male; Methylmalonic Acid; Middle Aged; Prospective Studies; Reference Values; ROC Curve; Sex Factors; Switzerland; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Accurate measurement of the essential micronutrients methionine, homocysteine, vitamins B6, B12, B9 and their metabolites in plasma, brain and maternal milk of mice using LC/MS ion trap analysis.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Male; Mass Spectrometry; Methionine; Mice; Mice, Inbred C57BL; Micronutrients; Milk; Vitamin B 12; Vitamin B 6 | 2015 |
[CME - laboratory 41. Evaluating vitamin B12 status].
Topics: Clinical Laboratory Techniques; Homocysteine; Humans; Methylmalonic Acid; Reference Values; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Correlation between MTHFR gene methylation and pre-eclampsia, and its clinical significance.
Topics: Adult; Case-Control Studies; DNA Methylation; Electrophoresis, Agar Gel; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Pre-Eclampsia; Pregnancy; Vitamin B 12 | 2015 |
Buccal Cytome Biomarkers and Their Association with Plasma Folate, Vitamin B12 and Homocysteine in Alzheimer's Disease.
Topics: Aged; Alzheimer Disease; Biomarkers; Cheek; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12 | 2015 |
Diabetic neuropathy is not associated with homocysteine, folate, vitamin B12 levels, and MTHFR C677T mutation in type 2 diabetic outpatients taking metformin.
Topics: Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Folic Acid; Follow-Up Studies; Genotype; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Outpatients; Prognosis; Vitamin B 12 | 2016 |
Low Cobalamin Levels as Predictors of Cobalamin Deficiency: Importance of Comorbidities Associated with Increased Oxidative Stress.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Comorbidity; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Oxidative Stress; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2016 |
Clinical characteristics of hemolytic uremic syndrome secondary to cobalamin C disorder in Chinese children.
Topics: Carrier Proteins; Child, Preschool; China; Female; Follow-Up Studies; Genetic Predisposition to Disease; Hemolytic-Uremic Syndrome; Homocysteine; Humans; Infant; Male; Mutation; Oxidoreductases; Rare Diseases; Retrospective Studies; Risk Assessment; Sampling Studies; Severity of Illness Index; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Erythrocyte fatty acid profiles and plasma homocysteine, folate and vitamin B6 and B12 in recurrent depression: Implications for co-morbidity with cardiovascular disease.
Topics: Adult; Cardiovascular Diseases; Comorbidity; Depressive Disorder, Major; Erythrocytes; Fatty Acids; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Oxidative Stress; Recurrence; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2015 |
Novel relationships between B12, folate and markers of inflammation, oxidative stress and NAD(H) levels, systemically and in the CNS of a healthy human cohort.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Antioxidants; Biomarkers; Central Nervous System; Deoxyguanosine; F2-Isoprostanes; Female; Folic Acid; Homocysteine; Humans; Inflammation; Interleukin-6; Linear Models; Male; Middle Aged; NAD; Oxidative Stress; Vitamin B 12 | 2015 |
The Dihydrofolate Reductase 19 bp Polymorphism Is Not Associated with Biomarkers of Folate Status in Healthy Young Adults, Irrespective of Folic Acid Intake.
Topics: Adult; Biomarkers; Cohort Studies; Diet; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Genetic Association Studies; Homocysteine; Humans; Introns; Ireland; Male; Nutritional Status; Polymorphism, Genetic; Tetrahydrofolate Dehydrogenase; Vitamin B 12; Young Adult | 2015 |
False-normal vitamin B12 results in a patient with pernicious anaemia.
Topics: Anemia, Pernicious; Diagnostic Errors; False Positive Reactions; Female; Homocysteine; Humans; Immunoassay; Methylmalonic Acid; Middle Aged; Vitamin B 12 | 2015 |
Plasma Homocysteine, Vitamin B12 and Folate Levels in Multiple System Atrophy: A Case-Control Study.
Topics: Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Multiple System Atrophy; Risk Factors; Vitamin B 12 | 2015 |
Assessing the association between homocysteine and cognition: reflections on Bradford Hill, meta-analyses, and causality.
Topics: Cognition; Cognition Disorders; Dementia; Dietary Supplements; Folic Acid; Homocysteine; Humans; Meta-Analysis as Topic; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2015 |
Prospective study of telomere length and LINE-1 methylation in peripheral blood cells: the role of B vitamins supplementation.
Topics: Aged; Blood Cells; Calcium; Cross-Sectional Studies; Dietary Supplements; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Long Interspersed Nucleotide Elements; Male; Middle Aged; Prospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Telomere; Tetrahydrofolates; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin D | 2016 |
Effects of an antioxidant beverage on biomarkers of oxidative stress in Alzheimer's patients.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Aged, 80 and over; Alanine Transaminase; Alzheimer Disease; Antioxidants; Aspartate Aminotransferases; Beverages; Biomarkers; Body Mass Index; C-Reactive Protein; Case-Control Studies; Deoxyguanosine; Female; Ferritins; Folic Acid; Glutathione Peroxidase; Homocysteine; Humans; Isoprostanes; Lipids; Male; Malus; Oxidative Stress; Plant Extracts; Protein Carbonylation; Superoxide Dismutase; Tea; Vitamin B 12 | 2016 |
Biochemical Identification of Vitamin B12 Deficiency in a Medical Office.
Topics: Ambulatory Care; Area Under Curve; Biomarkers; Cross-Sectional Studies; Early Diagnosis; Homocysteine; Humans; Immunoassay; Luminescent Measurements; Male; Methylmalonic Acid; Middle Aged; Office Visits; Predictive Value of Tests; ROC Curve; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Subjective well-being in older adults: folate and vitamin B12 independently predict positive affect.
Topics: Affect; Aged; Aged, 80 and over; Body Mass Index; Cross-Sectional Studies; Energy Intake; Energy Metabolism; Fatty Acids, Omega-3; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Socioeconomic Factors; Vitamin B 12 | 2015 |
Plasma Folate, Vitamin B12 and Homocysteine Levels in Children with Solid Tumors at Diagnosis; Results from a Pediatric Referral Centre.
Topics: Carcinogenesis; Case-Control Studies; Child, Preschool; Female; Folic Acid; Folic Acid Deficiency; Greece; Homocysteine; Humans; Male; Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Effect of multi-nutrient insufficiency on markers of one carbon metabolism in young women: response to a methionine load.
Topics: Adult; Amino Acids; Biomarkers; Body Height; Carbon; Female; Folic Acid; Food; Glutathione; Homocysteine; Humans; India; Malnutrition; Methionine; Ohio; Vitamin B 12; Vitamin B Complex | 2016 |
Evaluation of fatty acids in pregnancy: plasma or erythrocyte membrane?
Topics: Birth Weight; Fatty Acids; Female; Folic Acid; Homocysteine; Humans; Mothers; Pregnancy; Vitamin B 12 | 2015 |
Plasma homocysteine, folate and vitamin B12 levels in patients with lung cancer.
Topics: Adult; Aged; Case-Control Studies; Cell Transformation, Neoplastic; Folic Acid; Homocysteine; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Retrospective Studies; Vitamin B 12 | 2015 |
Evaluate the Effect of Valproate Monotherapy on the Serum Homocysteine, Folate and Vitamin B12 Levels in Epileptic Children.
Topics: Adolescent; Age Factors; Anticonvulsants; Case-Control Studies; Child; Child, Preschool; Drug Monitoring; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Risk Factors; Time Factors; Treatment Outcome; Valproic Acid; Vitamin B 12 | 2015 |
High red blood cell folate is associated with an increased risk of death among adults with diabetes, a 15-year follow-up of a national cohort.
Topics: Aged; Cause of Death; Cerebrovascular Disorders; Cohort Studies; Cotinine; Diabetes Mellitus, Type 2; Dietary Supplements; Dose-Response Relationship, Drug; Erythrocytes; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Nutrition Surveys; Proportional Hazards Models; Risk Factors; Socioeconomic Factors; Vitamin B 12 | 2015 |
The levels of vitamın B12, folate and homocysteine in mothers and their babies with neural tube defects.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Middle Aged; Neural Tube Defects; Pregnancy; Prevalence; Risk Factors; Turkey; Vitamin B 12; Young Adult | 2016 |
Nutritional Supplementation with Chlorella pyrenoidosa Lowers Serum Methylmalonic Acid in Vegans and Vegetarians with a Suspected Vitamin B₁₂ Deficiency.
Topics: Adult; Biological Availability; Chlorella; Diet, Vegan; Diet, Vegetarian; Dietary Supplements; Hematocrit; Hemoglobins; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Vegans; Vegetarians; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2015 |
B vitamins related to homocysteine metabolism in adults celiac disease patients: a cross-sectional study.
Topics: Adult; Celiac Disease; Cross-Sectional Studies; Diet Records; Diet, Gluten-Free; Female; Folic Acid; Homocysteine; Humans; Male; Nutritional Requirements; Nutritional Status; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2015 |
Effect of the one‑carbon unit cycle on overall DNA methylation in children with Down's syndrome.
Topics: Age Factors; Biomarkers; Carbon; Child; Child, Preschool; DNA Methylation; Down Syndrome; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12 | 2015 |
Elevated fibrinogen and lowered homocysteine-vitamin determinants and their association with left atrial thrombus in patients with rheumatic mitral stenosis.
Topics: Adult; Biomarkers; Blood Platelets; Cross-Sectional Studies; Female; Fibrinogen; Folic Acid; Heart Atria; Homocysteine; Humans; Male; Middle Aged; Mitral Valve; Mitral Valve Stenosis; Platelet Aggregation; Rheumatic Heart Disease; Thrombosis; Ultrasonography; Vitamin B 12 | 2015 |
Increased homocysteine levels exist in women with preeclampsia from early pregnancy.
Topics: Adult; Diet; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Prospective Studies; Vitamin B 12 | 2016 |
Hyperhomocysteinemia predicts renal function decline: a prospective study in hypertensive adults.
Topics: Aged; Blood Pressure; Cohort Studies; Demography; Female; Folic Acid; Follow-Up Studies; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Kidney; Male; Middle Aged; Prospective Studies; Renal Insufficiency, Chronic; Risk Factors; Vitamin B 12 | 2015 |
Laughing Gas in a Pediatric Emergency Department-Fun for All Participants: Vitamin B12 Status Among Medical Staff Working With Nitrous Oxide.
Topics: Adult; Anesthetics, Inhalation; Case-Control Studies; Cross-Sectional Studies; Emergency Service, Hospital; Female; Homocysteine; Humans; Male; Medical Staff; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Nitrous Oxide; Occupational Diseases; Occupational Exposure; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Associations of Polymorphisms in MTHFR Gene with the Risk of Age-Related Cataract in Chinese Han Population: A Genotype-Phenotype Analysis.
Topics: Aged; Aged, 80 and over; Aging; Asian People; Case-Control Studies; Cataract; Female; Genetic Predisposition to Disease; Haplotypes; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamin B 6 | 2015 |
Serum folate levels and fatality among diabetic adults: A 15-y follow-up study of a national cohort.
Topics: Aged; Cardiovascular Diseases; Cotinine; Diabetes Mellitus; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Neoplasms; Nutrition Surveys; Proportional Hazards Models; Retrospective Studies; Risk Factors; Socioeconomic Factors; Vitamin B 12 | 2016 |
Evaluation of oxidant and antioxidant status in patients with vitamin B12 deficiency.
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Case-Control Studies; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Oxidants; Oxidative Stress; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Young Adult | 2015 |
Homocysteine Levels Show Significant Differences among Mediterranean Dietary Quality Index Variables Compared to Folate and Vitamin B(12) Status in Women.
Topics: Adult; Aged; Aged, 80 and over; Diet Records; Diet, Mediterranean; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Vitamin B 12 | 2015 |
Maternal B vitamins: effects on offspring weight and DNA methylation at genomically imprinted domains.
Topics: Adult; Birth Weight; Cell Cycle Proteins; Child, Preschool; DNA Methylation; Female; Homocysteine; Humans; Infant, Newborn; Male; Pregnancy; RNA, Long Noncoding; Sarcoglycans; Transcription Factors; Tumor Suppressor Proteins; Vitamin B 12; Vitamin B 6; Weight Gain; Young Adult | 2016 |
Moderately elevated maternal homocysteine at preconception is inversely associated with cognitive performance in children 4 months and 6 years after birth.
Topics: Adult; Body Height; Body Mass Index; Body Weight; Brain; Child; Child Development; Cognition; Cross-Sectional Studies; Dietary Supplements; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Infant; Logistic Models; Male; Maternal Nutritional Physiological Phenomena; Micronutrients; Pregnancy; Prenatal Care; Prenatal Exposure Delayed Effects; Prospective Studies; Socioeconomic Factors; Spain; Vitamin B 12 | 2017 |
Effect of physical activity on levels of homocysteine, folate, and vitamin B12 in the elderly.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Exercise; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Motor Activity; Risk Factors; Vitamin B 12; Young Adult | 2016 |
Folic Acid and Vitamins D and B12 Correlate With Homocysteine in Chinese Patients With Type-2 Diabetes Mellitus, Hypertension, or Cardiovascular Disease.
Topics: Aged; Aged, 80 and over; Asian People; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hypertension; Male; Vitamin B 12; Vitamin D | 2016 |
Effects of Multivitamin Supplements on Cognitive Function, Serum Homocysteine Level, and Depression of Korean Older Adults With Mild Cognitive Impairment in Care Facilities.
Topics: Aged; Cognitive Dysfunction; Depression; Dietary Supplements; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Male; Republic of Korea; Residential Facilities; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2016 |
Low Serum Vitamin B-12 Concentrations Are Prevalent in a Cohort of Pregnant Canadian Women.
Topics: Adult; Canada; Diet; Dietary Supplements; DNA Methylation; Female; Fetal Blood; Fetus; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Prevalence; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2016 |
Metabolic dysregulation in first-episode schizophrenia patients with respect to genetic variation in one-carbon metabolism.
Topics: Adult; Betaine-Homocysteine S-Methyltransferase; Blood Glucose; Carbon; Case-Control Studies; Dyslipidemias; Fasting; Female; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, HDL; Male; Metabolic Syndrome; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Minor Histocompatibility Antigens; One-Carbon Group Transferases; Polymorphism, Genetic; Prevalence; Psychotic Disorders; Schizophrenia; Triglycerides; Vitamin B 12; Young Adult | 2016 |
Comparative case-control study of homocysteine, vitamin B
Topics: Adult; Anticonvulsants; Carbamazepine; Cardiovascular Diseases; Case-Control Studies; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Vitamin B 12 | 2017 |
Association of Vitamin B12, Folate, and Sulfur Amino Acids With Brain Magnetic Resonance Imaging Measures in Older Adults: A Longitudinal Population-Based Study.
Topics: Aged; Alzheimer Disease; Amino Acids, Sulfur; Atrophy; Brain; Female; Folic Acid; Homocysteine; Humans; Linear Models; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Risk Factors; Statistics as Topic; Sweden; Vitamin B 12; White Matter | 2016 |
Plasma Riboflavin and Vitamin B-6, but Not Homocysteine, Folate, or Vitamin B-12, Are Inversely Associated with Breast Cancer Risk in the European Prospective Investigation into Cancer and Nutrition-Varese Cohort.
Topics: Adult; Body Mass Index; Breast Neoplasms; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Italy; Logistic Models; Middle Aged; Nutritional Status; Premenopause; Prospective Studies; Riboflavin; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6 | 2016 |
Homocysteine metabolism and the associations of global DNA methylation with selected gene polymorphisms and nutritional factors in patients with dementia.
Topics: Aged; Aryldialkylphosphatase; Case-Control Studies; Dementia; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Interleukin-1beta; Male; Middle Aged; Poland; Polymorphism, Restriction Fragment Length; Tetrahydrofolates; Vitamin B 12 | 2016 |
Homocysteine, Liver Function Derangement and Brain Atrophy in Alcoholics.
Topics: Alcoholism; Atrophy; Brain; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Liver; Male; Middle Aged; Tomography, X-Ray Computed; Vitamin B 12; Vitamin B 6 | 2016 |
Maternal and Neonatal Markers of the Homocysteine Pathway and Fetal Growth: The Generation R Study.
Topics: Adult; Biomarkers; Birth Weight; Female; Fetal Blood; Fetal Development; Folic Acid; Homocysteine; Humans; Infant, Newborn; Male; Maternal Nutritional Physiological Phenomena; Netherlands; Pregnancy; Pregnancy Proteins; Prenatal Exposure Delayed Effects; Prospective Studies; Vascular Endothelial Growth Factor Receptor-1; Vitamin B 12 | 2016 |
Lack of association between the methylenetetrahydropholate reductase gene A1298C polymorphism and neural tube defects in a Turkish study group.
Topics: Adult; Child; Child, Preschool; Female; Gene Frequency; Genetic Association Studies; Genotype; Homocysteine; Humans; Infant; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube; Neural Tube Defects; Risk Factors; Turkey; Vitamin B 12 | 2016 |
Plasma-aminothiols status and inverse correlation of total homocysteine with B-vitamins in arsenic exposed population of West Bengal, India.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arsenic; Bangladesh; Calibration; Case-Control Studies; Chromatography, High Pressure Liquid; Creatinine; Cysteine; Dipeptides; Drinking Water; Environmental Exposure; Environmental Health; Female; Folic Acid; Glutathione; Homocysteine; Humans; India; Male; Malnutrition; Middle Aged; Nutritional Status; Socioeconomic Factors; Vitamin B 12; Vitamin B Complex; Young Adult | 2016 |
Nutritional Intake and Status of Cobalamin and Folate among Non-Pregnant Women of Reproductive Age in Bhaktapur, Nepal.
Topics: Adolescent; Adult; Body Mass Index; Body Weight; Cross-Sectional Studies; Energy Intake; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Linear Models; Methylmalonic Acid; Nepal; Nutritional Status; Prevalence; Socioeconomic Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2016 |
Artificial Neural Networks Link One-Carbon Metabolism to Gene-Promoter Methylation in Alzheimer's Disease.
Topics: Age Factors; Aged; Alzheimer Disease; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Biomarkers; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neural Networks, Computer; Presenilin-1; Promoter Regions, Genetic; Sex Factors; Vitamin B 12 | 2016 |
Association between Plasma Homocysteine Levels and Neuronal Injury in HIV Infection.
Topics: Adult; Antiretroviral Therapy, Highly Active; Female; Folic Acid; HIV Infections; Homocysteine; Humans; Male; Middle Aged; Neurofilament Proteins; Neurons; Vitamin B 12 | 2016 |
Multi-Vitamin B Supplementation Reverses Hypoxia-Induced Tau Hyperphosphorylation and Improves Memory Function in Adult Mice.
Topics: Animals; Avoidance Learning; Cerebral Cortex; Choline; Dietary Supplements; Disease Models, Animal; Folic Acid; Glycogen Synthase Kinase 3 beta; Hippocampus; Homocysteine; Hypoxia; Male; Maze Learning; Memory; Memory Disorders; Mice; Phosphorylation; tau Proteins; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2016 |
Homocysteine metabolism is associated with cerebrospinal fluid levels of soluble amyloid precursor protein and amyloid beta.
Topics: Adult; Albumins; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Apolipoprotein E4; Female; Folic Acid; Healthy Volunteers; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Peptide Fragments; Reference Values; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 2016 |
Evaluation of maternal serum folate, vitamin B12, and homocysteine levels andfactor V Leiden, factor II g.20210G>A, and MTHFR variations in prenatallydiagnosed neural tube defects.
Topics: Female; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Pregnancy; Prothrombin; Vitamin B 12 | 2016 |
Influence of food groups on plasma total homocysteine for specific MTHFR C677T genotypes in Chinese population.
Topics: Adult; Aged; Asian People; Diet; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Vitamin B 12 | 2017 |
Vitamin B12 status in women of childbearing age in the UK and its relationship with national nutrient intake guidelines: results from two National Diet and Nutrition Surveys.
Topics: Adult; Cross-Sectional Studies; Diet; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Malnutrition; Nutrition Policy; Nutrition Surveys; Prevalence; United Kingdom; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2016 |
[Association of Crohn's disease with transcobalamin Ⅱ gene polymorphisms and serum homocysteine, folate and vitamin B12 levels in Chinese patients].
Topics: Alleles; Crohn Disease; Folic Acid; Folic Acid Deficiency; Genotype; Haplotypes; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Mutation; Polymorphism, Genetic; Prevalence; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Impaired homocysteine metabolism in patients with alcoholic liver disease in Taiwan.
Topics: Adult; Case-Control Studies; Folic Acid; Glutathione; Homocysteine; Humans; Liver Diseases, Alcoholic; Male; Taiwan; Thiobarbituric Acid Reactive Substances; Vitamin B 12; Young Adult | 2016 |
Lipid profile status and other related factors in patients with Hyperphenylalaninaemia.
Topics: Apolipoproteins A; Apolipoproteins B; Blood Pressure; C-Reactive Protein; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Cross-Sectional Studies; Female; Homocysteine; Humans; Lipids; Male; Methionine; Phenylketonurias; Risk Factors; Triglycerides; Vitamin B 12 | 2016 |
Prospective associations of maternal betaine status with offspring weight and body composition at birth: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort study.
Topics: Adipose Tissue; Adolescent; Adult; Betaine; Birth Weight; Body Composition; Body Mass Index; Choline; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Infant; Linear Models; Male; Methionine; Middle Aged; Nutritional Status; Prospective Studies; Sensitivity and Specificity; Singapore; Vitamin B 12; Young Adult | 2016 |
Molecular and cellular effects of vitamin B12 forms on human trophoblast cells in presence of excessive folate.
Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Chorionic Gonadotropin, beta Subunit, Human; Cobamides; Cytoprotection; Dietary Supplements; Dose-Response Relationship, Drug; ErbB Receptors; Female; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Malondialdehyde; Pregnancy; Protective Agents; Trophoblasts; Tumor Necrosis Factor-alpha; Vitamin B 12 | 2016 |
Plant-based diet and vitamin B12.
Topics: Atherosclerosis; Diet, Vegetarian; Homocysteine; Humans; Vitamin B 12; Vitamin B Complex | 2016 |
Lower serum B12 vitamin concentrations are not accompanied by hyperhomocysteinaemia in chronic spontaneous urticaria.
Topics: Adult; Atherosclerosis; Biomarkers; C-Reactive Protein; Chronic Disease; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Immunoturbidimetry; Luminescent Measurements; Male; Severity of Illness Index; Time Factors; Urticaria; Vitamin B 12 | 2017 |
Evaluation of Homocysteine, Vitamin B12 and Folic Acid Levels During all the Trimesters in Pregnant and Preeclamptic Womens.
Topics: Case-Control Studies; Female; Fetal Blood; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Pregnancy; Pregnancy Trimesters; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Associations of Milk Consumption and Vitamin B₂ and Β
Topics: Adolescent; Animals; Anthropometry; Calcium, Dietary; Child; Child Development; Child Nutritional Physiological Phenomena; Cross-Sectional Studies; Diet; Female; Greece; Homocysteine; Humans; Male; Methylmalonic Acid; Milk; Physical Endurance; Physical Fitness; Regression Analysis; Riboflavin; Vitamin B 12; Zinc | 2016 |
Serum folate predicts muscle strength: a pilot cross-sectional study of the association between serum vitamin levels and muscle strength and gait measures in patients >65 years old with diabetes mellitus in a primary care setting.
Topics: Accidental Falls; Aged; Cross-Sectional Studies; Diabetes Mellitus; Female; Folic Acid; Folic Acid Deficiency; Gait; Hand Strength; Homocysteine; Humans; Hyperhomocysteinemia; Male; Muscle Strength; Pilot Projects; Primary Health Care; Risk Factors; Singapore; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D; Vitamin D Deficiency | 2016 |
Serum Homocysteine, Vitamin B12 and Folic Acid Levels in Patients with Metabolic Syndrome.
Topics: Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Metabolic Syndrome; Middle Aged; Vitamin B 12 | 2016 |
Methylfolate Trap Promotes Bacterial Thymineless Death by Sulfa Drugs.
Topics: Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Folic Acid; Homocysteine; Methionine; Microbial Sensitivity Tests; Vitamin B 12 | 2016 |
Comparative Assessment of Vitamin-B12, Folic Acid and Homocysteine Levels in Relation to p53 Expression in Megaloblastic Anemia.
Topics: Aged; Aged, 80 and over; Anemia, Megaloblastic; Bone Marrow Examination; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Tumor Suppressor Protein p53; Up-Regulation; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Red blood cell distribution width predicts homocysteine levels in adult population without vitamin B
Topics: Adult; Biomarkers; Erythrocyte Indices; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Physical Examination; Platelet Count; Predictive Value of Tests; Vitamin B 12 | 2017 |
Characteristic peripheral blood smear findings in disorders of cobalamin metabolism.
Topics: Erythrocytes, Abnormal; Ferredoxin-NADP Reductase; Homocysteine; Humans; Infant; Male; Methionine; Mutation; Neutrophils; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Homocysteine-reducing B vitamins and ischemic heart disease: a separate-sample Mendelian randomization analysis.
Topics: Adult; Aged; Case-Control Studies; Coronary Artery Disease; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Mendelian Randomization Analysis; Middle Aged; Myocardial Infarction; Odds Ratio; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamin B Complex | 2017 |
Folate, homocysteine and selected vitamins and minerals status in infertile women.
Topics: Adult; Cross-Sectional Studies; Female; Ferritins; Folic Acid; Homocysteine; Humans; Infertility, Female; Iron; Trace Elements; Vitamin A; Vitamin B 12; Vitamin B Complex; Vitamin E | 2017 |
Increased Coagulation With Aging: Importance of Homocysteine and Vitamin B12.
Topics: Adult; Aged; Aged, 80 and over; Aging; Atrial Fibrillation; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Thrombophilia; Vitamin B 12 | 2017 |
Increased Coagulation With Aging: Importance of Homocysteine and Vitamin B12 - Reply.
Topics: Aging; Homocysteine; Humans; Hyperhomocysteinemia; Thrombophilia; Vitamin B 12 | 2017 |
Communication: Homocysteine, Thioretinaco Ozonide, Oxidative Phosphorylation, Biosynthesis of Phosphoadenosine Phosphosulfate and the Pathogenesis of Atherosclerosis.
Topics: Animals; Atherosclerosis; Guinea Pigs; Homocysteine; Humans; Oxidation-Reduction; Oxidative Phosphorylation; Phosphoadenosine Phosphosulfate; Vitamin B 12 | 2016 |
Increased serum level of homocysteine correlates with retinal nerve fiber layer thinning in diabetic retinopathy.
Topics: Adult; Aged; Cross-Sectional Studies; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nerve Fibers; Prospective Studies; Retinal Ganglion Cells; Tomography, Optical Coherence; Vitamin B 12 | 2016 |
Blood folic acid, vitamin B12, and homocysteine levels in pregnant women with fetal growth restriction.
Topics: Adult; China; Female; Fetal Growth Retardation; Folic Acid; Folic Acid Deficiency; Gestational Age; Homocysteine; Humans; Infant, Newborn; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2016 |
Association between the MTHFR C677T polymorphism, blood folate and vitamin B12 deficiency, and elevated serum total homocysteine in healthy individuals in Yunnan Province, China.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2017 |
Periconceptional maternal one-carbon biomarkers are associated with embryonic development according to the Carnegie stages.
Topics: Adult; Biomarkers; Cohort Studies; Crown-Rump Length; Embryonic Development; Female; Folic Acid; Homocysteine; Humans; Pregnancy; Prospective Studies; Ultrasonography, Prenatal; Vitamin B 12; Young Adult | 2017 |
Serum high concentrations of homocysteine and low levels of folic acid and vitamin B
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; China; Coronary Artery Disease; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Incidence; Male; Middle Aged; Prevalence; Retrospective Studies; Risk Factors; Severity of Illness Index; Vitamin B 12 | 2017 |
Patterns of Biomarkers in Cord Blood During Pregnancy and Preeclampsia.
Topics: Apoprotein(a); Biomarkers; Female; Fetal Blood; Folic Acid; Heme Oxygenase-1; Homocysteine; Humans; Infant, Newborn; Lipids; Pre-Eclampsia; Pregnancy; Thyroid Hormones; Thyrotropin; Vitamin B 12 | 2017 |
Maternal and Fetal Folate, Vitamin B
Topics: Albuminuria; Child; Child, Preschool; Cohort Studies; Female; Fetal Blood; Folic Acid; Follow-Up Studies; Glomerular Filtration Rate; Homocysteine; Humans; Infant; Infant, Newborn; Kidney Function Tests; Male; Maternal-Fetal Exchange; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Vitamin B 12 | 2017 |
Vitamin B
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Depression; Female; Homocysteine; Humans; Incidence; Linear Models; Longitudinal Studies; Male; Multivariate Analysis; Netherlands; Proportional Hazards Models; Prospective Studies; Vitamin B 12 | 2017 |
Serum Homocysteine, Folate, and Vitamin B12 Levels in Carbamazepine Treated Epileptic Children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12 | 2016 |
Regular breakfast consumption is associated with higher blood vitamin status in adolescents: the HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence) Study.
Topics: Adolescent; Ascorbic Acid; Body Composition; Body Mass Index; Body Weight; Breakfast; Child; Cross-Sectional Studies; Diet; Female; Folic Acid; Health Behavior; Healthy Lifestyle; Homocysteine; Humans; Male; Mental Recall; Nutrition Assessment; Nutritional Status; Socioeconomic Factors; Specimen Handling; Surveys and Questionnaires; Transcobalamins; Vitamin B 12; Vitamin D; Vitamins | 2017 |
Interactions among methylenetetrahydrofolate reductase (MTHFR) and cystathionine β-synthase (CBS) polymorphisms - a cross-sectional study: multiple heterozygosis as a risk factor for higher homocysteine levels and vaso-occlusive episodes.
Topics: Adolescent; Adult; Brazil; Cross-Sectional Studies; Cystathionine beta-Synthase; Epistasis, Genetic; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Linkage Disequilibrium; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Thrombophilia; Thrombosis; Vitamin B 12; Young Adult | 2017 |
Association between hyperhomocysteinemia and stroke with atherosclerosis and small artery occlusion depends on homocysteine metabolism-related vitamin levels in Chinese patients with normal renal function.
Topics: Aged; Aged, 80 and over; Asian People; Case-Control Studies; Cerebrovascular Disorders; China; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Arteriosclerosis; Kidney; Male; Middle Aged; Retrospective Studies; Stroke; Vitamin B 12 | 2017 |
Anemia and hematinic deficiencies in gastric parietal cell antibody-positive and -negative oral mucosal disease patients with microcytosis.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Autoantibodies; Erythrocyte Count; Erythrocyte Indices; Female; Homocysteine; Humans; Male; Middle Aged; Mouth Diseases; Mouth Mucosa; Parietal Cells, Gastric; Vitamin B 12 | 2017 |
Vitamin B-12 status in infancy is positively associated with development and cognitive functioning 5 y later in Nepalese children.
Topics: Adult; Asia; Child Development; Cognition; Cognitive Dysfunction; Female; Homocysteine; Humans; Infant; Male; Methylmalonic Acid; Nepal; Neurodevelopmental Disorders; Neuropsychological Tests; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2017 |
High folate and low vitamin B12 status during pregnancy is associated with gestational diabetes mellitus.
Topics: Adult; China; Cohort Studies; Comorbidity; Cross-Sectional Studies; Diabetes, Gestational; Female; Folic Acid; Homocysteine; Humans; India; Malaysia; Male; Nutritional Status; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2018 |
Ratios of One-Carbon Metabolites Are Functional Markers of B-Vitamin Status in a Norwegian Coronary Angiography Screening Cohort.
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Biomarkers; Carbon; Creatinine; Cross-Sectional Studies; Cystathionine beta-Synthase; Cysteine; Female; Genetic Variation; Homocysteine; Humans; Male; Metabolic Networks and Pathways; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Norway; Nutritional Status; Vitamin B 12; Vitamin B Complex; Young Adult | 2017 |
Plasma homocysteine levels are associated with macular thickness in type 2 diabetes without diabetic macular edema.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Macula Lutea; Macular Edema; Male; Middle Aged; Regression Analysis; Vitamin B 12 | 2018 |
The Impact of Homocysteine, Vitamin B12, and Vitamin D Levels on Functional Outcome after First-Ever Ischaemic Stroke.
Topics: Aged; Aged, 80 and over; Brain Ischemia; Female; Homocysteine; Humans; Male; Middle Aged; Recovery of Function; Stroke; Vitamin B 12; Vitamin D | 2017 |
Effect of B9 and B12 vitamin intake on semen parameters and fertility of men with MTHFR polymorphisms.
Topics: Adult; Azoospermia; Case-Control Studies; Dietary Supplements; Fertility; Folic Acid; Gene Frequency; Heterozygote; Homocysteine; Homozygote; Humans; Iran; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oligospermia; Phenotype; Polymorphism, Genetic; Severity of Illness Index; Vitamin B 12 | 2017 |
Joint effect of maternal plasma homocysteine and prepregnancy obesity on child blood pressure: a prospective birth cohort study.
Topics: Adult; Biomarkers; Blood Pressure; Body Mass Index; Boston; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Male; Mothers; Obesity; Oxidative Stress; Preconception Care; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Risk Factors; Time Factors; Vitamin B 12 | 2017 |
An Analysis of Transcobalamin II Gene Polymorphisms and Serum Levels of Homocysteine, Folate and Vitamin B12 in Chinese Patients with Crohn's Disease.
Topics: Adult; Asian People; Case-Control Studies; Crohn Disease; Female; Folic Acid; Genetic Association Studies; Haplotypes; Homocysteine; Humans; Hyperhomocysteinemia; Male; Polymorphism, Single Nucleotide; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2017 |
Vitamin B12, folic acid, homocysteine and vitamin D levels in children and adolescents with obsessive compulsive disorder.
Topics: Adolescent; Biomarkers; Child; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Vitamin B 12; Vitamin D; Vitamin D Deficiency | 2017 |
B vitamins and pollution, an interesting, emerging, yet incomplete picture of folate and the exposome.
Topics: Environmental Pollution; Folic Acid; Homocysteine; Humans; Vitamin B 12; Vitamin B Complex | 2017 |
Diagnostic Values of Serum Levels of Homocysteine and Uric Acid for Predicting Vascular Mild Cognitive Impairment in Patients with Cerebral Small Vessel Disease.
Topics: Aged; Case-Control Studies; Cerebral Small Vessel Diseases; Cholesterol; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Middle Aged; ROC Curve; Uric Acid; Vitamin B 12 | 2017 |
Vitamin B12, folate and homocysteine status in obese and atopic children: a preliminary study.
Topics: Child; Child, Preschool; Folic Acid; Homocysteine; Humans; Hypersensitivity; Pediatric Obesity; Respiratory Tract Infections; Vitamin B 12 | 2018 |
Toxoplasma Gondii Moderates the Association between Multiple Folate-Cycle Factors and Cognitive Function in U.S. Adults.
Topics: Adult; Biomarkers; Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nutrition Surveys; Sample Size; Socioeconomic Factors; Toxoplasma; Toxoplasmosis; Vitamin B 12; Young Adult | 2017 |
A Black Cohosh Extract Causes Hematologic and Biochemical Changes Consistent with a Functional Cobalamin Deficiency in Female B6C3F1/N Mice.
Topics: Anemia, Megaloblastic; Animals; Body Weight; Cimicifuga; Female; Folic Acid; Homocysteine; Kidney; Liver; Methylmalonic Acid; Mice; Plant Extracts; Tetrahydrofolate Dehydrogenase; Vitamin B 12; Vitamin B 12 Deficiency | 2017 |
One-Carbon Metabolism Biomarkers and Cognitive Decline in the Very Old: The Newcastle 85+ Study.
Topics: Aged, 80 and over; Biomarkers; Cognitive Dysfunction; England; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Prospective Studies; Vitamin B 12 | 2017 |
Influence of phenylketonuria's diet on dimethylated arginines and methylation cycle.
Topics: Arginine; Biomarkers; Child; Chromatography, High Pressure Liquid; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Mass Spectrometry; Methylation; Patient Compliance; Phenylketonurias; Severity of Illness Index; Vitamin B 12 | 2017 |
The importance of folate, vitamins B6 and B12 for the lowering of homocysteine concentrations for patients with recurrent pregnancy loss and MTHFR mutations.
Topics: Abortion, Habitual; Adult; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Pregnancy; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2017 |
Plasma Homocysteine and Serum Folate and Vitamin B
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Male; Odds Ratio; Psychiatric Status Rating Scales; Risk Factors; Vitamin B 12 | 2017 |
Folate serum levels in Italian women entering an in vitro fertilization program.
Topics: Adult; Female; Fertilization in Vitro; Folic Acid; Homocysteine; Humans; Infertility, Female; Vitamin B 12 | 2017 |
Serum methylmalonic acid correlates with neuropathic pain in idiopathic Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Biomarkers; Cross-Sectional Studies; Female; Homocysteine; Humans; Levodopa; Male; Methylmalonic Acid; Middle Aged; Neural Conduction; Neuralgia; Pain Measurement; Parkinson Disease; Prevalence; Severity of Illness Index; Vitamin B 12 | 2017 |
Relevance of plasma levels of free homocysteine and methionine as risk predictors for ischemic stroke in the young.
Topics: Adolescent; Adult; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Odds Ratio; Risk Factors; Stroke; Vitamin B 12; Vitamin B 6; Young Adult | 2018 |
Folate and vitamin B12 status is associated with insulin resistance and metabolic syndrome in morbid obesity.
Topics: Adult; Body Mass Index; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Insulin Resistance; Male; Metabolic Syndrome; Methylmalonic Acid; Middle Aged; Obesity, Morbid; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Blood lead, cadmium and mercury in relation to homocysteine and C-reactive protein in women of reproductive age: a panel study.
Topics: Adolescent; Adult; C-Reactive Protein; Cadmium; Diet; Female; Folic Acid; Homocysteine; Humans; Lead; Linear Models; Mercury; Metals, Heavy; New York; Prospective Studies; Vitamin B 12; Vitamin B 6; Young Adult | 2017 |
Homocysteine Metabolism and Hematological Parameters in Early Stage of Phenytoin Treated Epileptic Children.
Topics: Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Phenytoin; Vitamin B 12 | 2017 |
Homocysteine Biochemistry and Cognitive Decline in the Elderly.
Topics: Aged; Biomarkers; Carbon; Cognitive Dysfunction; Homocysteine; Humans; Vitamin B 12 | 2017 |
Folate, vitamin B12, homocysteine and polymorphisms in folate metabolizing genes in children with congenital heart disease and their mothers.
Topics: Adult; Case-Control Studies; Child; Child, Preschool; Ferredoxin-NADP Reductase; Folic Acid; Gene-Environment Interaction; Genetic Predisposition to Disease; Heart Defects, Congenital; Homocysteine; Humans; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Polymorphism, Single Nucleotide; Risk Factors; Socioeconomic Factors; Vitamin B 12; Young Adult | 2017 |
Pregnant women of South Asian ethnicity in Canada have substantially lower vitamin B12 status compared with pregnant women of European ethnicity.
Topics: Adult; Asia; Asian People; Biomarkers; Canada; Europe; Female; Homocysteine; Humans; Pregnancy; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency; White People; Young Adult | 2017 |
The Association of Thyroid Function With Maternal and Neonatal Homocysteine Concentrations.
Topics: Adult; Birth Weight; Cohort Studies; Dietary Supplements; Female; Fetal Blood; Folic Acid; Genetic Variation; Homocysteine; Humans; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Prospective Studies; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Vitamin B 12; Vitamins | 2017 |
Hyperhomocysteinemia as a Risk Factor for Saccular Intracranial Aneurysm: A Cohort Study in a Chinese Han Population.
Topics: Adult; Aged; Asian People; Biomarkers; Case-Control Studies; Chi-Square Distribution; China; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Intracranial Aneurysm; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Prospective Studies; Protective Factors; Risk Factors; Up-Regulation; Vitamin B 12 | 2017 |
[Association of transcobalamine II gene polymorphisms and serum homocysteine, vitamin B
Topics: Adult; Colitis, Ulcerative; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12 | 2017 |
Homocysteine concentrations in the cognitive progression of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition; Disease Progression; Female; Folic Acid; Geriatric Assessment; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Mental Status and Dementia Tests; Neuropsychological Tests; Nutrition Assessment; Nutritional Status; Surveys and Questionnaires; Time Factors; Up-Regulation; Vitamin B 12 | 2017 |
Vitamin Status and the Development of Postoperative Cognitive Decline in Elderly Surgical Oncologic Patients.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neoplasms; Preoperative Period; Vitamin B 12 | 2018 |
Correlation of Maternal Serum Homocysteine in the First Trimester with the Development of Gestational Hypertension and Preeclampsia.
Topics: Adult; Biomarkers; Blood Pressure; Body Mass Index; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Hypertension, Pregnancy-Induced; Logistic Models; Odds Ratio; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Retrospective Studies; Risk Assessment; Risk Factors; Vitamin B 12 | 2017 |
Folate: a possible role in erectile dysfunction?
Topics: Adult; Case-Control Studies; Erectile Dysfunction; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Severity of Illness Index; Surveys and Questionnaires; Ultrasonography; Vitamin B 12 | 2018 |
Vitamin B12 and Homocysteine Associations with Gait Speed in Older Adults: The Baltimore Longitudinal Study of Aging.
Topics: Aged; Aged, 80 and over; Aging; Baltimore; Female; Folic Acid; Gait; Homocysteine; Humans; Linear Models; Longitudinal Studies; Male; Middle Aged; Vitamin B 12; Walking Speed | 2017 |
Homocysteine pathway and in vitro fertilization outcome.
Topics: Adolescent; Adult; Erythrocytes; Female; Fertilization in Vitro; Folic Acid; Homocysteine; Humans; Pregnancy; Pregnancy Rate; Prospective Studies; Vitamin B 12; Young Adult | 2018 |
Color Doppler imaging of the retrobulbar circulation and plasmatic biomarkers of vascular risk in age-related macular degeneration: A pilot study.
Topics: Aged; Aged, 80 and over; Biomarkers; Blood Circulation; C-Reactive Protein; Ciliary Arteries; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Ophthalmic Artery; Orbit; Pilot Projects; Retinal Artery; Severity of Illness Index; Ultrasonography, Doppler, Color; Vitamin B 12; Wet Macular Degeneration | 2018 |
Association between Maternal and Infantile Markers of Cobalamin Status During the First Month Post-Delivery.
Topics: Breast Feeding; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant; Infant, Newborn; Male; Pregnancy; Prenatal Exposure Delayed Effects; Turkey; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Cognitive impairment is associated with elevated serum homocysteine levels among older adults.
Topics: Aged; Causality; Cognitive Dysfunction; Cohort Studies; Comorbidity; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Prevalence; Republic of Korea; Vitamin B 12 | 2019 |
Relation of serum levels of homocysteine, vitamin B12 and folate to cognitive functions in multiple sclerosis patients.
Topics: Adult; Brain; Case-Control Studies; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Linear Models; Magnetic Resonance Imaging; Male; Multiple Sclerosis; Psychometrics; Statistics, Nonparametric; Vitamin B 12 | 2018 |
Evaluation of Vitamin B12 Deficiency and Associated Factors in Patients With Systemic Sclerosis.
Topics: Correlation of Data; Cross-Sectional Studies; Female; Gastrointestinal Tract; Helicobacter pylori; Homocysteine; Humans; Immunoglobulin G; Male; Middle Aged; Nutritional Status; Scleroderma, Systemic; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Association of elevated homocysteine levels and Methylenetetrahydrofolate reductase (MTHFR) 1298 A > C polymorphism with Vitiligo susceptibility in Gujarat.
Topics: Adolescent; Adult; Case-Control Studies; Child; Computer Simulation; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Vitamin B 12; Vitiligo; Young Adult | 2018 |
Identification of vitamin B12 deficiency in vegetarian Indians.
Topics: Adult; Biomarkers; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Sample Size; Vegetarians; Vitamin B 12; Vitamin B 12 Deficiency; White People | 2018 |
Unilateral Apraxic Agraphia without Ideomotor Apraxia from a callosal lesion in a patient with Marchiafava-Bignami disease.
Topics: Adult; Agraphia; Apraxias; Corpus Callosum; Female; Folic Acid; Functional Laterality; Homocysteine; Humans; Magnetic Resonance Imaging; Marchiafava-Bignami Disease; Vitamin B 12 | 2018 |
Interplay of vitamin D, vitamin B
Topics: Absorptiometry, Photon; Aged; Bone Density; Cross-Sectional Studies; Female; Homocysteine; Humans; Middle Aged; Osteoporosis, Postmenopausal; Postmenopause; Vitamin B 12; Vitamin D | 2018 |
Early changes in vitamin B12 uptake and biomarker status following Roux-en-Y gastric bypass and sleeve gastrectomy.
Topics: Adult; Aged; Avitaminosis; Biomarkers; Female; Gastrectomy; Gastric Bypass; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Obesity, Morbid; Postoperative Complications; Prospective Studies; Transcobalamins; Vitamin B 12 | 2019 |
Early pregnancy folate-cobalamin interactions and their effects on cobalamin status and hematologic variables throughout pregnancy.
Topics: Adult; Anemia, Iron-Deficiency; Body Mass Index; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Iron, Dietary; Longitudinal Studies; Methylmalonic Acid; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Prevalence; Socioeconomic Factors; Vitamin B 12 | 2018 |
Elevated Total Homocysteine in All Participants and Plasma Vitamin B12 Concentrations in Women Are Associated With All-Cause and Cardiovascular Mortality in the Very Old: The Newcastle 85+ Study.
Topics: Aged, 80 and over; Aging; Biomarkers; Cardiovascular Diseases; Correlation of Data; Demography; Erythrocytes; Female; Folic Acid; Health Status Disparities; Homocysteine; Humans; Male; Risk Assessment; Risk Factors; Sex Factors; Socioeconomic Factors; United Kingdom; Vitamin B 12 | 2018 |
Topics: Atherosclerosis; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Melatonin; Mitochondria; Oxidative Phosphorylation; Oxidative Stress; S-Adenosylmethionine; Vitamin B 12 | 2018 |
S100B, Homocysteine, Vitamin B12, Folic Acid, and Procalcitonin Serum Levels in Remitters to Electroconvulsive Therapy: A Pilot Study.
Topics: Adult; Aged; Biomarkers; Calcitonin; Depressive Disorder, Major; Electroconvulsive Therapy; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Pilot Projects; Remission Induction; S100 Calcium Binding Protein beta Subunit; Severity of Illness Index; Treatment Outcome; Vitamin B 12 | 2018 |
Oxidative stress and dietary micronutrient deficiencies contribute to overexpression of epigenetically regulated genes by lupus T cells.
Topics: Adult; Aged; Case-Control Studies; CD4-Positive T-Lymphocytes; Choline; Diet; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Female; Flow Cytometry; Folic Acid; Gene Expression Regulation; Homocysteine; Humans; Lupus Erythematosus, Systemic; Male; Methionine; Micronutrients; Middle Aged; Oxidative Stress; Peroxynitrous Acid; Riboflavin; T-Lymphocytes; Vitamin B 12; Vitamin B 6; Young Adult; Zinc | 2018 |
Relationship between plasma levels of homocysteine and the related B vitamins in patients with hemodialysis adequacy or inadequacy.
Topics: Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Renal Dialysis; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2018 |
Metabolic distress in lipid & one carbon metabolic pathway through low vitamin B-12: a population based study from North India.
Topics: Adult; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cross-Sectional Studies; Dyslipidemias; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Obesity; Triglycerides; Vitamin B 12; Vitamin B 12 Deficiency; Waist Circumference | 2018 |
Significantly higher frequencies of hemoglobin, iron, vitamin B12, and folic acid deficiencies and of hyperhomocysteinemia in patients with Behcet's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia; Behcet Syndrome; Case-Control Studies; Erythrocyte Indices; Female; Folic Acid; Folic Acid Deficiency; Hematinics; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2018 |
One-carbon metabolite ratios as functional B-vitamin markers and in relation to colorectal cancer risk.
Topics: Betaine; Biomarkers, Tumor; Carbon; Case-Control Studies; Colorectal Neoplasms; Creatinine; Cysteine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Riboflavin; Vitamin B 12; Vitamin B Complex | 2019 |
Evaluation of tracer labelled methionine load test in vitamin B-12 deficient adolescent women.
Topics: Administration, Oral; Adolescent; Body Mass Index; Carbon Dioxide; Carbon Isotopes; Dietary Supplements; Fasting; Female; Folic Acid; Homocysteine; Humans; Iron; Methionine; Serologic Tests; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Association of hyperhomocysteinemia with genetic variants in key enzymes of homocysteine metabolism and methotrexate toxicity in rheumatoid arthritis patients.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Thymidylate Synthase; Tunisia; Vitamin B 12 | 2018 |
Classical Homocystinuria in a Juvenile Patient.
Topics: Child, Preschool; Chromatography, Ion Exchange; Cystathionine beta-Synthase; Folic Acid; Homocysteine; Homocystinuria; Humans; Male; Pyridoxine; Treatment Outcome; Vitamin B 12 | 2018 |
Maternal and infant vitamin B12 status during infancy predict linear growth at 5 years.
Topics: Adolescent; Adult; Breast Feeding; Child, Preschool; Diet; Female; Folic Acid; Growth; Homocysteine; Humans; Infant; Lactation; Limit of Detection; Male; Methylmalonic Acid; Middle Aged; Nepal; Random Allocation; Vitamin B 12; Young Adult | 2018 |
Loss of the Thioretinaco Ozonide Oxygen Adenosine Triphosphate Complex from Mitochondria Produces Mitochondrial Dysfunction and Carcinogenesis.
Topics: Adenosine Triphosphate; Carcinogenesis; Catalytic Domain; Heterocyclic Compounds; Homocysteine; Humans; Mitochondria; Mitochondrial Diseases; Neoplasms; Oxidation-Reduction; Oxidative Phosphorylation; Oxidative Stress; Oxygen; Reactive Oxygen Species; Vitamin B 12 | 2018 |
A dietary pattern derived using B-vitamins and its relationship with vascular markers over the life course.
Topics: Adult; Carotid Intima-Media Thickness; Cohort Studies; Diet; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Pulse Wave Analysis; United Kingdom; Vitamin B 12; Vitamin B Complex | 2019 |
Maternal one carbon metabolism and arsenic methylation in a pregnancy cohort in Mexico.
Topics: Adult; Arsenic; Biomarkers; Cohort Studies; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Male; Methylation; Mexico; Pregnancy; Pregnant Women; Regression Analysis; Vitamin B 12; Young Adult | 2018 |
Subclinical atherosclerosis and impaired cardiac autonomic control in pediatric patients with Vitamin B12 deficiency.
Topics: Adolescent; Atherosclerosis; Autonomic Nervous System; Biomarkers; Carotid Artery, Common; Carotid Intima-Media Thickness; Case-Control Studies; Child; Echocardiography; Female; Heart; Heart Rate; Homocysteine; Humans; Hyperhomocysteinemia; Male; Microscopy, Acoustic; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Clinical and imaging characteristics of subacute combined degeneration complicated with white matter lesions in the brain: a report of five cases.
Topics: Aged; Atrophy; Cognition Disorders; Female; Homocysteine; Humans; Leukoencephalopathies; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Retrospective Studies; Subacute Combined Degeneration; Vitamin B 12 | 2018 |
Association between increased plasma levels of homocysteine and depression observed in individuals with primary lactose malabsorption.
Topics: Adult; Body Mass Index; Depression; Female; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Lactase; Lactose Intolerance; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2018 |
Vitamin D Supplementation and Nordic Walking Training Decreases Serum Homocysteine and Ferritin in Elderly Women.
Topics: Aged; Aged, 80 and over; Calcium-Regulating Hormones and Agents; Cholecalciferol; Dietary Supplements; Female; Ferritins; Folic Acid; Homocysteine; Humans; Middle Aged; Vitamin B 12; Walking | 2018 |
Development of a Dietary Methyl Donor Food Frequency Questionnaire to Assess Folate and Vitamin B
Topics: Adolescent; Biomarkers; Child; Child, Preschool; CpG Islands; DNA Methylation; DNA, Viral; Epigenesis, Genetic; Erythrocytes; Female; Folic Acid; Hepatitis B virus; Hepatitis B, Chronic; Homocysteine; Humans; Male; Surveys and Questionnaires; Vitamin B 12 | 2018 |
Association of vitamin B12 mediated hyperhomocysteinemia and methylenetetrafolate reductase (C677T) gene polymorphism with cognitive impairment: A population based study from North India.
Topics: Adult; Aged; Cognitive Dysfunction; Comorbidity; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Vitamin B 12 | 2018 |
A case report of branch retinal artery occlusion in a teenager due to hyperhomocysteinaemia; the interplay of genetic and nutritional defects.
Topics: Adolescent; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Malnutrition; Methylenetetrahydrofolate Reductase (NADPH2); Retinal Artery Occlusion; Vision Disorders; Visual Acuity; Visual Field Tests; Visual Fields; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Folate/Vitamin B Alleviates Hyperhomocysteinemia-Induced Alzheimer-Like Pathologies in Rat Retina.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Dietary Supplements; Disease Models, Animal; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Rats, Sprague-Dawley; Retina; Retinal Vessels; tau Proteins; Vitamin B 12 | 2019 |
Homocysteine, Pyridoxine, Folate and Vitamin B12 Levels in Children with Attention Deficit Hyperactivity Disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Behavior Rating Scale; Child; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Pyridoxine; Reference Values; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency; Wechsler Scales | 2018 |
Impaired Homocysteine Metabolism Associated with High Plasma Interleukin-17A Levels, a Pro-Atherogenic Marker, in an Endogamous Population of North India.
Topics: Adult; Biomarkers; Female; Forkhead Transcription Factors; Homocysteine; Humans; Hyperhomocysteinemia; India; Interleukin-10; Interleukin-17; Leukocytes, Mononuclear; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Population Surveillance; Prevalence; Vitamin B 12 | 2018 |
Fisher discriminant analysis for classification of autism spectrum disorders based on folate-related metabolism markers.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Autism Spectrum Disorder; Biomarkers; Case-Control Studies; Child; Child, Preschool; Discriminant Analysis; Female; Folic Acid; Homocysteine; Humans; Male; Polymorphism, Single Nucleotide; S-Adenosylhomocysteine; Tetrahydrofolates; Transcobalamins; Vitamin B 12 | 2019 |
Predictors of serum cobalamin and its association with homocysteine in community-dwelling older adults.
Topics: Age Factors; Aged; Body Composition; Cross-Sectional Studies; Diet; Female; Folic Acid; Homocysteine; Humans; Independent Living; Inflammatory Bowel Diseases; Male; Neoplasms; Sex Factors; Vitamin B 12 | 2019 |
Association of pre-eclampsia risk with maternal levels of folate, homocysteine and vitamin B12 in Colombia: A case-control study.
Topics: Adolescent; Adult; Biomarkers; Case-Control Studies; Colombia; Female; Folic Acid; Homocysteine; Humans; Pre-Eclampsia; Pregnancy; Vitamin B 12; Young Adult | 2018 |
Higher maternal plasma folate, vitamin B
Topics: Adolescent; Adult; Biomarkers; Birth Weight; Blood Pressure; Case-Control Studies; Female; Fetal Blood; Folic Acid; Gestational Age; Homocysteine; Humans; Infant, Newborn; Infant, Premature; Nutritional Status; Pre-Eclampsia; Pregnancy; Premature Birth; Up-Regulation; Vitamin B 12; Young Adult | 2019 |
Prudent dietary pattern influences homocysteine level more than folate, vitamin B12, and docosahexaenoic acid: a structural equation model approach.
Topics: Adolescent; Adult; Cross-Sectional Studies; Diet; Docosahexaenoic Acids; Female; Folic Acid; Homocysteine; Humans; Life Style; Male; Middle Aged; Models, Theoretical; Socioeconomic Factors; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2020 |
Patients with cobalamin G or J defect missed by the current newborn screening program: diagnosis and novel mutations.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Metabolism, Inborn Errors; ATP-Binding Cassette Transporters; Child; Child, Preschool; China; Exome Sequencing; Female; Homocysteine; Humans; Infant; Infant, Newborn; Male; Mutation; Neonatal Screening; Tandem Mass Spectrometry; Vitamin B 12 | 2019 |
The Revised D-A-CH-Reference Values for the Intake of Vitamin B
Topics: Adolescent; Adult; Biological Availability; Child; Child, Preschool; Female; Homocysteine; Humans; Infant; Male; Pregnancy; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2019 |
B-vitamins in Relation to Depression in Older Adults Over 60 Years of Age: The Trinity Ulster Department of Agriculture (TUDA) Cohort Study.
Topics: Aged; Aging; Biomarkers; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Depression; Female; Folic Acid; Homocysteine; Humans; Ireland; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Pyridoxine; Vitamin B 12; Vitamin B Complex | 2019 |
One-carbon metabolism biomarkers and risk of urothelial cell carcinoma in the European prospective investigation into cancer and nutrition.
Topics: Aged; Biomarkers, Tumor; Carcinoma, Transitional Cell; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Prospective Studies; Risk Assessment; Smoking; Urinary Bladder Neoplasms; Vitamin B 12; Vitamin B 6 | 2019 |
Is the routine screening for hyperhomocysteinaemia recommended in patients with chronic plaque psoriasis?
Topics: Chronic Disease; Folic Acid; Homocysteine; Humans; Psoriasis; Vitamin B 12 | 2019 |
The impact of homocysteine, B
Topics: Adult; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; HIV; HIV Seropositivity; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12; Vitamin D; Vitamin D Deficiency; Vitamins | 2019 |
Reference values of a new serum folate assay traceable to the WHO International Standard.
Topics: Adolescent; Adult; Aged; Biomarkers; Blood Chemical Analysis; Folic Acid; Homocysteine; Humans; Middle Aged; Reference Values; Vitamin B 12; World Health Organization; Young Adult | 2019 |
Homocysteine and small vessel stroke: A mendelian randomization analysis.
Topics: Brain Ischemia; Homocysteine; Humans; Mendelian Randomization Analysis; Microvessels; Polymorphism, Single Nucleotide; Stroke; Vitamin B 12 | 2019 |
Methylmalonic Acid and Homocysteine as Indicators of Vitamin B12 Deficiency in Patients with Gastric Cancer after Gastrectomy.
Topics: Adult; Aged; Biomarkers; Female; Gastrectomy; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Postoperative Complications; Retrospective Studies; Stomach Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Developmental Impairments in a Rat Model of Methyl Donor Deficiency: Effects of a Late Maternal Supplementation with Folic Acid.
Topics: Animals; Behavior, Animal; Dietary Supplements; Disease Models, Animal; Female; Folic Acid; Growth and Development; Homocysteine; Methylation; MicroRNAs; Nervous System; Pregnancy; Rats, Wistar; Vitamin B 12 | 2019 |
Relationship between Homocysteine, Folate, Vitamin B
Topics: Aged; Aged, 80 and over; Female; Folic Acid; Hand Strength; Homes for the Aged; Homocysteine; Humans; Hyperhomocysteinemia; Lower Extremity; Male; Muscle Strength; Nutritional Status; Physical Functional Performance; Regression Analysis; Sex Factors; Vitamin B 12 | 2019 |
Serum folate and vitamin B
Topics: Adult; Aged; Atherosclerosis; Cohort Studies; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Incidence; Male; Middle Aged; Republic of Korea; Risk Factors; Surveys and Questionnaires; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Homocysteine Metabolism in Children and Adolescents: Influence of Age on Plasma Biomarkers and Correspondent Genotype Interactions.
Topics: Adolescent; Age Factors; Biomarkers; Child; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Vitamin B 12; Vitamin B Complex | 2019 |
Klotho, vitamin D and homocysteine levels during acute episode and remission periods in schizophrenia patients.
Topics: Acute Disease; Adult; Aged; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Glucuronidase; Homocysteine; Humans; Klotho Proteins; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Vitamin B 12; Vitamin D; Young Adult | 2019 |
Co-relation of Cerebral Venous Sinus Thrombosis with Vitamin B12 and Homocysteine Levels in a Tertiary Care Centre.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Sinus Thrombosis, Intracranial; Tertiary Care Centers; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Associations among serum folate, waist-to-hip ratio, lipid profile, and eating habits with homocysteine in an elderly Thai population.
Topics: Aged; Cross-Sectional Studies; Feeding Behavior; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Thailand; Vitamin B 12; Waist-Hip Ratio | 2019 |
Maternal vitamin D deficiency increases the thromboxane/prostacyclin ratio through alterations in the one-carbon cycle in Wistar rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcium; Cyclooxygenase 2; Cystathionine beta-Synthase; Disease Models, Animal; Female; Folic Acid; Gene Expression Regulation; Group II Phospholipases A2; Homocysteine; Humans; Malondialdehyde; Parathyroid Hormone; Phosphates; Placenta; Pregnancy; Rats; Rats, Wistar; Signal Transduction; Thromboxane B2; Vitamin B 12; Vitamin D Deficiency | 2019 |
The relationship between homocysteine level and vitamins B12, B9 and B6 status in patients with chronic kidney disease.
Topics: Folic Acid; Homocysteine; Humans; Renal Insufficiency, Chronic; Ukraine; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2019 |
Investigating vitamin B12 deficiency.
Topics: Adult; Aged; Biomarkers; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Infant; Malabsorption Syndromes; Male; Malnutrition; Methylmalonic Acid; Physical Examination; Practice Guidelines as Topic; Pregnancy; Referral and Consultation; Risk Factors; United Kingdom; Vitamin B 12; Vitamin B 12 Deficiency; Vulnerable Populations | 2019 |
Is there a possible relationship between gastric intestinal metaplasia and systemic arterial stiffness?
Topics: Adult; Aged; Chronic Disease; Female; Folic Acid; Gastritis; Gastritis, Atrophic; Homocysteine; Humans; Intestines; Male; Metaplasia; Middle Aged; Pulse Wave Analysis; Stomach; Vascular Stiffness; Vitamin B 12 | 2019 |
Association between homocysteine, vitamin B
Topics: Adult; Aged; China; Cross-Sectional Studies; Erectile Dysfunction; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Surveys and Questionnaires; Vitamin B 12 | 2019 |
The concomitant lower concentrations of vitamins B6, B9 and B12 may cause methylation deficiency in autistic children.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Autism Spectrum Disorder; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cystathionine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Male; Mass Spectrometry; Methionine; Methylation; Mutation; Oxidation-Reduction; Phenotype; Vitamin B 12; Vitamin B 6 | 2019 |
Association Between Cognitive Impairment and Vitamin B12, Folate, and Homocysteine Status in Elderly Adults: A Retrospective Study.
Topics: Aged; Aged, 80 and over; Biomarkers; Cognitive Dysfunction; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Homocysteine Serum Levels as Prognostic Marker of Hepatocellular Carcinoma with Portal Vein Thrombosis.
Topics: Adult; Aged; Biomarkers, Tumor; Budd-Chiari Syndrome; Carcinoma, Hepatocellular; Cholesterol, LDL; Female; Folic Acid; Homocysteine; Humans; Liver Neoplasms; Male; Middle Aged; Portal Vein; Prognosis; Vitamin B 12; Vitamin B 6 | 2019 |
A genetic epidemiological study in British adults and older adults shows a high heritability of the combined indicator of vitamin B
Topics: Adult; Aged; Aged, 80 and over; Alkyl and Aryl Transferases; Biomarkers; Energy Metabolism; Female; Ferredoxin-NADP Reductase; Genome-Wide Association Study; Homocysteine; Humans; Male; Metabolism, Inborn Errors; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Middle Aged; Mitochondria; Molecular Epidemiology; Polymorphism, Single Nucleotide; Thiolester Hydrolases; Transcobalamins; Valine; Vitamin B 12 | 2019 |
Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in atrophic glossitis patients with or without microcytosis.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Atrophy; Autoantibodies; Case-Control Studies; Erythrocyte Indices; Erythropoiesis; Female; Folic Acid; Folic Acid Deficiency; Glossitis; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Iron Deficiencies; Male; Middle Aged; Parietal Cells, Gastric; Tongue; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2019 |
Maternal and cord blood homocysteine, vitamin B12, folate, and B-type natriuretic peptide levels at term for predicting congenital heart disease of the neonate: A case-control study.
Topics: Case-Control Studies; Female; Fetal Blood; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Natriuretic Peptide, Brain; Pregnancy; Vitamin B 12 | 2020 |
Does serum gastric parietal cell antibody titer have influence on anemia and vitamin B12 deficiency in atrophic glossitis patients?
Topics: Adult; Aged; Aged, 80 and over; Anemia, Macrocytic; Atrophy; Autoantibodies; Case-Control Studies; Erythrocyte Indices; Female; Folic Acid; Glossitis; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Parietal Cells, Gastric; Tongue; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in atrophic glossitis patients with macrocytosis.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Anemia, Macrocytic; Atrophy; Autoantibodies; Case-Control Studies; Erythrocyte Indices; Female; Folic Acid; Glossitis; Hematinics; Hematologic Diseases; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Parietal Cells, Gastric; Tongue; Vitamin B 12; Young Adult | 2019 |
Association of Serum Homocysteine, Vitamin B12 and Folic Acid Levels with Metabolic Syndrome.
Topics: Folic Acid; Homocysteine; Humans; Metabolic Syndrome; Vitamin B 12 | 2018 |
Hyperhomocysteinemia is key for increased susceptibility to PND in aged mice.
Topics: Animals; Cognition; Dietary Supplements; Folic Acid; Homocysteine; Hyperhomocysteinemia; Mice; Postoperative Cognitive Complications; Postoperative Period; Preoperative Period; Risk Factors; S-Adenosylmethionine; Vitamin B 12 | 2019 |
A novel approach in the management of hyperhomocysteinemia.
Topics: Alcohol Oxidoreductases; Animals; Choline; Cytidine Diphosphate Choline; Dietary Supplements; Endothelial Cells; Folic Acid; Homocysteine; Humans; Hydrolysis; Hyperhomocysteinemia; Kidney; Life Style; Liver; Methionine; Models, Theoretical; Vitamin B 12; Vitamin B 6 | 2019 |
Relationship between folate, vitamin B
Topics: Aged; Case-Control Studies; China; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Transaminases; Vitamin B 12 | 2020 |
Serum homocysteine and vitamin B12 levels in women with gestational diabetes mellitus.
Topics: Adult; Blood Glucose; Body Mass Index; Case-Control Studies; Diabetes, Gestational; Female; Glucose Tolerance Test; Glycated Hemoglobin; Homocysteine; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Pregnancy; Prospective Studies; Vitamin B 12; Young Adult | 2019 |
Serum Vitamin B12 and Methylmalonic Acid Status in Migraineurs: A Case-Control Study.
Topics: Adolescent; Adult; Anthropometry; Case-Control Studies; Cost of Illness; Disease Progression; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Migraine Disorders; Nutritional Status; Pain Measurement; Social Class; Vitamin B 12; Young Adult | 2019 |
Changes in intracellular folate metabolism during high-dose methotrexate and Leucovorin rescue therapy in children with acute lymphoblastic leukemia.
Topics: Adolescent; Antidotes; Child; Child, Preschool; Erythrocytes; Female; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Infant; Leucovorin; Male; Metabolic Networks and Pathways; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Vitamin B 12 | 2019 |
Blood concentrations of vitamins B1, B6, B12, C and D and folate in palliative care patients: Results of a cross-sectional study.
Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Palliative Care; Thiamine; Vitamin B 12; Vitamin B 6 | 2019 |
Isolated subacute combined degeneration in late-onset cobalamin C deficiency in children: Two case reports and literature review.
Topics: Adolescent; Ataxia; Brain; Carrier Proteins; Child; Female; Homocysteine; Homocystinuria; Humans; Injections, Intravenous; Late Onset Disorders; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Mutation; Oxidoreductases; Subacute Combined Degeneration; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2019 |
Serum total homocysteine level in Iraqi woman with unexplained recurrent Miscarriage.
Topics: Abortion, Habitual; Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; ROC Curve; Sensitivity and Specificity; Vitamin B 12 | 2019 |
A Cross-Sectional Study of Serum Folate and Vitamin B12 Levels in Psychiatric Inpatients.
Topics: Adult; Comorbidity; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; India; Inpatients; Male; Mental Disorders; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Prenatal folate, homocysteine and vitamin B
Topics: Brain; Child; Child Behavior Disorders; Cognition Disorders; Cohort Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Language Development Disorders; Magnetic Resonance Imaging; Male; Netherlands; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Hyperhomocysteinemia induced locked-in syndrome in a young adult due to folic acid deficiency.
Topics: Adolescent; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Locked-In Syndrome; Male; Vitamin B 12; Young Adult | 2021 |
Comment on 'The effects of isotretinoin therapy on serum homocysteine, folate and vitamin B12 levels in patients with acne': may retinoids be useful to treat hyperhomocysteinemia found in patients affected by hidradenitis suppurativa?
Topics: Acne Vulgaris; Folic Acid; Hidradenitis Suppurativa; Homocysteine; Humans; Hyperhomocysteinemia; Isotretinoin; Retinoids; Vitamin B 12 | 2020 |
Association between metformin dose and vitamin B12 deficiency in patients with type 2 diabetes.
Topics: Age Factors; Aged; Alcohol Drinking; Anemia; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Odds Ratio; Republic of Korea; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2019 |
Interictal epileptiform discharges on electroencephalography in children with methylenetetrahydrofolate reductase (MTHFR) polymorphisms.
Topics: Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Infant; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Vitamin B 12 | 2020 |
The relationship between cognitive impairment and homocysteine in a B12 and folate deficient population in China: A cross-sectional study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; China; Cognitive Dysfunction; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
A prospective observational study of on-treatment plasma homocysteine levels as a biomarker of toxicity, depression and vitamin supplementation lead-in time pre pemetrexed, in patients with non-small cell lung cancer and malignant mesothelioma.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Carcinoma, Non-Small-Cell Lung; Depression; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Lung Neoplasms; Male; Mesothelioma; Mesothelioma, Malignant; Middle Aged; Pemetrexed; Prospective Studies; Treatment Outcome; Vitamin B 12; Vitamins | 2019 |
Effect of imbalance in folate and vitamin B12 in maternal/parental diet on global methylation and regulatory miRNAs.
Topics: Animals; Brain; Carrier Proteins; Diet; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Fetal Growth Retardation; Fetus; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Developmental; Homocysteine; Kidney; Liver; Male; Maternal Exposure; Mice; Mice, Inbred C57BL; MicroRNAs; Paternal Exposure; Placenta; Pregnancy; Pregnancy Complications; Reverse Transcriptase Polymerase Chain Reaction; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Reduced serum concentrations of vitamin B
Topics: Adult; Cross-Sectional Studies; Diabetes, Gestational; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Pregnancy; Pregnancy Trimester, First; Saudi Arabia; Thyrotropin; Vitamin B 12; Vitamins | 2019 |
Relationship between metformin use and vitamin B
Topics: Aged; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Erythrocyte Indices; Female; Hemoglobins; Homocysteine; Humans; Hypoglycemic Agents; Japan; Male; Metformin; Middle Aged; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Trends of folate, vitamin B
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; India; Pregnancy; Pregnancy Outcome; Pregnancy Trimesters; Vitamin B 12; Vitamin B Complex; Young Adult | 2020 |
Assessment of cellular cobalamin metabolism in Gaucher disease.
Topics: beta-Glucosidase; Cell Culture Techniques; Female; Fibroblasts; Gaucher Disease; Glucosylceramidase; Homocysteine; Humans; Lysosomes; Male; Methylmalonic Acid; Mutation; Phenotype; Saposins; Transcobalamins; Vitamin B 12 | 2020 |
Normal serum cobalamin levels do not exclude the diagnosis of pernicious anaemia: a case report.
Topics: Anemia, Pernicious; Female; Folic Acid Deficiency; Gastritis, Atrophic; Homocysteine; Humans; Hydroxocobalamin; Methylmalonic Acid; Middle Aged; Tetrahydrofolates; Vitamin B 12; Vitamin B Complex | 2020 |
A Clinical study to determine levels of vitamin B12,Folic acid and Homocysteine in patients of Ischemic stroke.
Topics: Brain Ischemia; Folic Acid; Homocysteine; Humans; Ischemic Stroke; Stroke; Vitamin B 12 | 2020 |
Trace Element Status in Children with Infantile Tremor Syndrome: An Inductively Coupled Plasma-Mass Spectrometry Based Study.
Topics: Adolescent; Child; Cross-Sectional Studies; Female; Ferritins; Homocysteine; Humans; India; Magnesium; Male; Mass Spectrometry; Plasma; Selenium; Trace Elements; Tremor; Vitamin B 12; Vitamin B 12 Deficiency; Zinc | 2020 |
Identification and characterization of a bacterial core methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Chloroflexi; Dehalococcoides; Escherichia coli; Genome, Bacterial; Homocysteine; Methionine; Methylation; Phylogeny; Vitamin B 12 | 2020 |
Plasma homocysteine levels in patients with keratoconus.
Topics: Folic Acid; Homocysteine; Humans; Keratoconus; Prospective Studies; Vitamin B 12 | 2020 |
The relationship between dietary patterns and depression mediated by serum levels of Folate and vitamin B12.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Depression; Depressive Disorder, Major; Female; Folic Acid; Homocysteine; Humans; Iran; Logistic Models; Male; Middle Aged; Tryptophan; Vitamin B 12; Young Adult | 2020 |
Association of MTHFR C677T polymorphism with elevated homocysteine level and disease development in vitiligo.
Topics: Adolescent; Adult; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Homozygote; Humans; Iran; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Vitamin B 12; Vitiligo; Young Adult | 2020 |
Elevated cerebrospinal fluid homocysteine is associated with blood-brain barrier disruption in amyotrophic lateral sclerosis patients.
Topics: Amyotrophic Lateral Sclerosis; Blood-Brain Barrier; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 2020 |
Diagnostic Accuracy of Holotranscobalamin, Vitamin B12, Methylmalonic Acid, and Homocysteine in Detecting B12 Deficiency in a Large, Mixed Patient Population.
Topics: Adult; Aged; Biomarkers; Cohort Studies; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Retrospective Studies; ROC Curve; Sensitivity and Specificity; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Assessment of folate and cobalamin concentrations in relation to their dependent intracellular metabolites in serum of pigs between 6 and 26 weeks of age.
Topics: Animals; Cytoplasm; Folic Acid; Homocysteine; Methylmalonic Acid; Serum; Sus scrofa; Vitamin B 12 | 2020 |
Serum homocysteine and folate concentrations in early pregnancy and subsequent events of adverse pregnancy outcome: the Sichuan Homocysteine study.
Topics: Adult; Case-Control Studies; China; Female; Folic Acid; Homocysteine; Humans; Infant, Low Birth Weight; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Premature Birth; Retrospective Studies; Risk Factors; Vitamin B 12 | 2020 |
An unusually high plasma concentration of homocysteine resulting from a combination of so-called "secondary" etiologies.
Topics: Aged; Betaine; Female; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Leucovorin; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Psychotic Disorders; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2020 |
Maternal B12, Folate and Homocysteine Concentrations and Offspring Cortisol and Cardiovascular Responses to Stress.
Topics: Adolescent; Adult; Cardiovascular System; Female; Folic Acid; Homocysteine; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Stress, Psychological; Vitamin B 12; Young Adult | 2020 |
Comparison of Vitamin B12, Vitamin D, and Folic Acid Blood Levels in Plumbism Patients and Controls in Eastern Iran.
Topics: Case-Control Studies; Folic Acid; Homocysteine; Humans; Iran; Lead Poisoning; Vitamin B 12; Vitamin D; Vitamins | 2021 |
Relationship between cobalt transporter II gene rs9606756 site mutant and serum homocysteine level and recurrent cerebral infarction in young and middle-aged people.
Topics: Adult; Age Factors; Alleles; Cerebral Infarction; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Middle Aged; Point Mutation; Polymorphism, Genetic; Recurrence; Transcobalamins; Vitamin B 12 | 2021 |
[Correlation of the levels of seminal plasma homocysteine, folate and cobalamin with semen parameters in obese men].
Topics: Folic Acid; Homocysteine; Humans; Infertility, Male; Male; Obesity; Semen; Semen Analysis; Sperm Count; Sperm Motility; Spermatozoa; Vitamin B 12 | 2018 |
The relationship of severity of depression with homocysteine, folate, vitamin B12, and vitamin D levels in children and adolescents.
Topics: Adolescent; Child; Depressive Disorder; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Severity of Illness Index; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D | 2020 |
Homocysteine is associated with severity of microvasculopathy in sickle cell disease patients.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Child; Child, Preschool; Creatine; Folic Acid; Homocysteine; Humans; Intravital Microscopy; Microcirculation; Middle Aged; Pyridoxal Phosphate; Severity of Illness Index; Thrombotic Microangiopathies; Vitamin B 12 | 2020 |
A pilot study to assess the effect of a three-month vitamin supplementation containing L-methylfolate on systemic homocysteine plasma concentrations and retinal blood flow in patients with diabetes.
Topics: Adolescent; Adult; Aged; Blood Circulation; Diabetes Mellitus; Dietary Supplements; Female; Homocysteine; Humans; Male; Middle Aged; Pilot Projects; Retina; Retinal Vessels; Tetrahydrofolates; Tomography, Optical Coherence; Vitamin B 12; Vitamins | 2020 |
Effects of MTHFR C677T polymorphism on vitamin D, homocysteine and natural killer cell cytotoxicity in women with recurrent pregnancy losses.
Topics: Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Killer Cells, Natural; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pregnancy; Retrospective Studies; Vitamin B 12; Vitamin D; Vitamins | 2020 |
Functional vitamin B12 deficiency in phenylketonuria patients and healthy controls: An evaluation with combined indicator of vitamin B12 status as a biochemical index.
Topics: Adolescent; Biomarkers; Case-Control Studies; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Phenylketonurias; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Distribution characteristics of circulating homocysteine and folate and related factors in agriculture, stock-raising and urban populations: a cross-sectional survey.
Topics: Agriculture; Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12 | 2021 |
Hyperhomocysteinemia in patients with acute porphyrias: A potentially dangerous metabolic crossroad?
Topics: Cystathionine beta-Synthase; Homocysteine; Humans; Hyperhomocysteinemia; Porphyria, Acute Intermittent; Vitamin B 12 | 2020 |
Hyperhomocysteinemia is Associated with Inflammation, Bone Resorption, Vitamin B12 and Folate Deficiency and MTHFR C677T Polymorphism in Postmenopausal Women with Decreased Bone Mineral Density.
Topics: Bone Density; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Osteitis; Osteoporosis, Postmenopausal; Oxidoreductases; Polymorphism, Genetic; Postmenopause; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Dynamics and interactions of cobalamin and folate status during advanced aging - a longitudinal study in a community-dwelling cohort with multiple follow-ups.
Topics: Aged; Aging; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Independent Living; Longitudinal Studies; Vitamin B 12 | 2020 |
Hyperhomocysteinemia and Low Folate and Vitamin B12 Are Associated with Vascular Dysfunction and Impaired Nitric Oxide Sensitivity in Morbidly Obese Patients.
Topics: Adult; Alcohol Drinking; Arterioles; Bariatric Surgery; Brachial Artery; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nitric Oxide; Nutritional Status; Obesity, Morbid; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Assessment of Reference Range of Serum Homocysteine from the Post-therapy Values of Cobalamin and Folate Deficiency Patients.
Topics: Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Which one, gastric parietal cell antibody positivity or hyperhomocysteinemia, is a better biomarker to predict oral mucosal disease patients with vitamin B12 deficiency?
Topics: Biomarkers; Case-Control Studies; Folic Acid; Folic Acid Deficiency; Glossitis; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Parietal Cells, Gastric; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
Relationship between intake and plasma concentrations of vitamin B12 and folate in 873 adults with a physically active lifestyle: a cross-sectional study.
Topics: Adult; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Life Style; Male; Nutritional Status; Vitamin B 12 | 2021 |
Adolescent/adult-onset homocysteine remethylation disorders characterized by gait disturbance with/without psychiatric symptoms and cognitive decline: a series of seven cases.
Topics: Adolescent; Adult; Cognitive Dysfunction; Gait Disorders, Neurologic; Homocysteine; Homocystinuria; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2021 |
B-vitamins and metabolic syndrome in Mesoamerican children and their adult parents.
Topics: Adult; Child; Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Metabolic Syndrome; Parents; Vitamin B 12; Vitamin B Complex | 2021 |
Associations of Plasma Folate and Vitamin B6 With Blood DNA Methylation Age: An Analysis of One-Carbon Metabolites in the VA Normative Aging Study.
Topics: Aged; Aging; Biomarkers; CpG Islands; DNA Methylation; Epigenesis, Genetic; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Regression Analysis; Veterans; Vitamin B 12; Vitamin B 6 | 2021 |
Lipid Risk Factors in Vitiligo: Homocysteine the Connecting Link?
Topics: Adult; Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Lipids; Risk Factors; Vitamin B 12; Vitiligo | 2020 |
Diagnostic Characteristics of 3-Parameter and 2-Parameter Equations for the Calculation of a Combined Indicator of Vitamin B12 Status to Predict Cobalamin Deficiency in a Large Mixed Patient Population.
Topics: Biomarkers; Homocysteine; Humans; Methylmalonic Acid; ROC Curve; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Association between plasma levels of homocysteine, folate, and vitamin B
Topics: Aged; Blood Pressure; Cross-Sectional Studies; Diet; Female; Folic Acid; Homocysteine; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Prevalence; Preventive Medicine; Risk; Surveys and Questionnaires; Vitamin B 12 | 2020 |
Test utilization for the diagnosis of vitamin B12 and folate deficiency in local clinics in Korea.
Topics: Adult; Anemia, Macrocytic; Blood Chemical Analysis; Erythrocyte Indices; Folic Acid; Folic Acid Deficiency; Hematologic Tests; Homocysteine; Humans; Methylmalonic Acid; Republic of Korea; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Vitamin B12, folate levels and somatoform dissociation in conversion disorder.
Topics: Adolescent; Adult; Case-Control Studies; Conversion Disorder; Dissociative Disorders; Folic Acid; Homocysteine; Humans; Turkey; Vitamin B 12; Young Adult | 2020 |
The effect of folate and VitB
Topics: Aged; Cognition; Cognitive Dysfunction; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Treatment Outcome; Vitamin B 12 | 2020 |
[Remethylation disorders: about two cases].
Topics: Alcoholism; Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Infant, Newborn; Metabolic Networks and Pathways; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle Spasticity; Psychotic Disorders; Vitamin B 12 | 2020 |
Peripheral Neuropathy in
Topics: Adult; Aged; Case-Control Studies; Female; Homocysteine; Humans; Levodopa; Male; Middle Aged; Neural Conduction; Parkinson Disease; Peripheral Nervous System Diseases; Prevalence; Risk Factors; Uric Acid; Vitamin B 12 | 2020 |
B vitamin blood concentrations and one-carbon metabolism polymorphisms in a sample of Italian women and men attending a unit of transfusion medicine: a cross-sectional study.
Topics: Carbon; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Italy; Male; Transfusion Medicine; Vitamin B 12; Vitamin B Complex | 2021 |
Metabolic Groups Related to Blood Vitamin Levels and Inflammatory Biomarkers in Brazilian Children and Adolescents.
Topics: Adolescent; Biomarkers; Child; Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Vitamin B 12; Vitamin B Complex | 2020 |
Sex Differences in Folate Levels: A Cross Sectional Study of a Large Cohort from Israel.
Topics: Cardiometabolic Risk Factors; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Israel; Male; Middle Aged; Prevalence; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
The relationship between exacerbated diabetic peripheral neuropathy and metformin treatment in type 2 diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Homocysteine; Humans; Male; Metformin; Methylmalonic Acid; Middle Aged; Peripheral Nervous System Diseases; Risk Factors; Vitamin B 12 | 2021 |
A high frequency and geographical distribution of MMACHC R132* mutation in children with cobalamin C defect.
Topics: Adolescent; Child; Child, Preschool; Exons; Female; Homocysteine; Humans; India; Infant; Infant, Newborn; Male; Methylmalonic Acid; Oxidoreductases; Point Mutation; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
Association between serum folate with inflammatory markers, disease clinical activity and serum homocysteine in patients with inflammatory bowel disease. Does folate level have an effect on maintaining clinical remission?
Topics: Colitis; Folic Acid; Homocysteine; Humans; Inflammatory Bowel Diseases; Vitamin B 12 | 2020 |
POSITIVE EFFECT OF BETAINE-ARGININE SUPPLEMENT ON IMPROVED HYPERHOMOCYSTEINEMIA TREATMENT IN MARRIED COUPLES WITH REPRODUCTIVE DISORDERS.
Topics: Arginine; Betaine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12 | 2020 |
Four families of folate-independent methionine synthases.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Archaeal Proteins; Bacterial Proteins; Biosynthetic Pathways; Folic Acid; Homocysteine; Iron-Sulfur Proteins; Methionine; Models, Chemical; Molecular Structure; Multigene Family; Oxygen; Tetrahydrofolates; Vitamin B 12 | 2021 |
Effect of zinc supplementation on hemogram parameters and circulating concentrations of homocysteine, vitamin B
Topics: Adolescent; Child; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Prospective Studies; Vitamin B 12; Zinc | 2021 |
Cross-sectional association between vitamin B12 status and probable postpartum depression in Indian women.
Topics: Adolescent; Adult; Cesarean Section; Cross-Sectional Studies; Depression, Postpartum; Diet; Female; Homocysteine; Humans; India; Methylmalonic Acid; Pregnancy; Pregnancy, Unplanned; Risk Factors; S-Adenosylmethionine; Serotonin; Social Class; Tetrahydrofolates; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2021 |
Maternal vitamin B
Topics: Canada; Female; Homocysteine; Humans; Infant, Newborn; Mothers; Pregnancy; Premature Birth; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2021 |
Value of amniotic fluid homocysteine assay in prenatal diagnosis of combined methylmalonic acidemia and homocystinuria, cobalamin C type.
Topics: Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Female; Homocysteine; Homocystinuria; Humans; Methylmalonic Acid; Oxidoreductases; Pregnancy; Prenatal Diagnosis; Reproducibility of Results; Retrospective Studies; Vitamin B 12 | 2021 |
Cardiovascular manifestations of intermediate and major hyperhomocysteinemia due to vitamin B12 and folate deficiency and/or inherited disorders of one-carbon metabolism: a 3.5-year retrospective cross-sectional study of consecutive patients.
Topics: Adult; Cardiovascular Diseases; Child, Preschool; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Metabolism, Inborn Errors; Methylmalonic Acid; Middle Aged; Retrospective Studies; Vitamin B 12 | 2021 |
Associations of Early Pregnancy and Neonatal Circulating Folate, Vitamin B-12, and Homocysteine Concentrations with Cardiometabolic Risk Factors in Children at 10 y of Age.
Topics: Cardiometabolic Risk Factors; Cardiovascular Diseases; Child; Female; Folic Acid; Glucose; Homocysteine; Humans; Infant, Newborn; Micronutrients; Overweight; Pregnancy; Prospective Studies; Risk Factors; Vitamin B 12; Vitamins | 2021 |
Causal Effects of Homocysteine, Folate, and Cobalamin on Kidney Function: A Mendelian Randomization Study.
Topics: Alleles; Female; Folic Acid; Genome-Wide Association Study; Glomerular Filtration Rate; Homocysteine; Humans; Kidney; Male; Mendelian Randomization Analysis; Polymorphism, Single Nucleotide; Vitamin B 12 | 2021 |
Serum B12, homocysteine, and anti-parietal cell antibody levels in children with autism.
Topics: Autistic Disorder; Case-Control Studies; Child; Homocysteine; Humans; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
PECULIARITIES OF CHANGES IN HOMOCYSTEINE LEVELS DEPENDING ON VITAMIN STATUS IN PATIENTS WITH CHRONIC PANCREATITIS AND TYPE 2 DIABETES.
Topics: Diabetes Mellitus, Type 2; Folic Acid; Homocysteine; Humans; Pancreatitis, Chronic; Vitamin B 12 | 2021 |
Reference Interval for Korean Serum Folate Assay Traceable to the WHO International Standard.
Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Reference Values; Republic of Korea; Retrospective Studies; Vitamin B 12; World Health Organization | 2021 |
Homocysteine, B vitamins, and cardiovascular disease: a Mendelian randomization study.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Mendelian Randomization Analysis; Risk Factors; Vitamin B 12; Vitamin B Complex | 2021 |
Associations of circulating folate, vitamin B12 and homocysteine concentrations in early pregnancy and cord blood with epigenetic gestational age: the Generation R Study.
Topics: Adult; Cohort Studies; Epigenesis, Genetic; Epigenomics; Female; Fetal Blood; Folic Acid; Gestational Age; Homocysteine; Humans; Infant, Newborn; Male; Pregnancy; Prospective Studies; Vitamin B 12 | 2021 |
Implementation of second-tier tests in newborn screening for the detection of vitamin B
Topics: Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Neonatal Screening; Propionic Acidemia; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2021 |
Hyperhomocysteinemia-related serum metabolome alterations not normalized by short-term folic acid treatment.
Topics: Adolescent; Adult; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Metabolome; Vitamin B 12; Young Adult | 2021 |
Folate and vitamin B12 status: associations with maternal glucose and neonatal DNA methylation sites related to dysglycaemia, in pregnant women with obesity.
Topics: Diabetes, Gestational; DNA Methylation; Female; Folic Acid; Glucose; Homocysteine; Humans; Infant, Newborn; Obesity; Pregnancy; Pregnant Women; Vitamin B 12 | 2022 |
Association Between Homocysteine and Vitamin Levels in Demented Patients.
Topics: Aged; Aged, 80 and over; Dementia; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Thiamine; Vitamin B 12; Vitamin B 6 | 2021 |
Different dietary combinations of folic acid and vitamin B12 in parental diet results in epigenetic reprogramming of IGF2R and KCNQ1OT1 in placenta and fetal tissues in mice.
Topics: Animals; Body Weight; Brain; Diet; Dose-Response Relationship, Drug; Drug Interactions; Epigenesis, Genetic; Female; Fetus; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Developmental; Genomic Imprinting; Homocysteine; Kidney; Liver; Male; Mice; Placenta; Pregnancy; Pregnancy Complications; Receptor, IGF Type 2; RNA, Long Noncoding; RNA, Messenger; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
The marker of cobalamin deficiency, plasma methylmalonic acid, may help identifying lysosomal iron trapping in patients. Its possible utility for heart failure.
Topics: Heart Failure; Homocysteine; Humans; Iron; Lysosomes; Methylmalonic Acid; Vitamin B 12 | 2021 |
Reclaiming the importance of homocysteine as a marker of cardiovascular and neurologic disease.
Topics: Biomarkers; Cardiovascular System; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 2021 |
A study of hyperhomocysteinemia in cerebral venous sinus thrombosis.
Topics: Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; India; Methylenetetrahydrofolate Reductase (NADPH2); Risk Factors; Sinus Thrombosis, Intracranial; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Absence of MMACHC in peripheral retinal cells does not lead to an ocular phenotype in mice.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Metabolism, Inborn Errors; Animals; Female; Homocysteine; Homocystinuria; Humans; Male; Methylmalonic Acid; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Mutation; Oxidoreductases; Phenotype; Retina; Retinal Degeneration; Vitamin B 12; Young Adult | 2021 |
Homocysteine, vitamin B status and MTHFR polymorphisms in Italian infertile women.
Topics: Female; Folic Acid; Genotype; Homocysteine; Humans; Infertility, Female; Italy; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12; Vitamin B Complex | 2021 |
Higher serum homocysteine level and frequency of hyperhomocysteinemia in carcinoembryonic antigen-positive or squamous cell carcinoma-antigen-positive oral leukoplakia patients.
Topics: Antigens, Neoplasm; Autoantibodies; Carcinoembryonic Antigen; Erythrocyte Indices; Folic Acid; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Leukoplakia, Oral; Parietal Cells, Gastric; Serpins; Vitamin B 12 | 2021 |
Hyperhomocysteinemia in patients with acute porphyrias: a possible effect of ALAS1 modulation by siRNAm therapy and its control by vitamin supplementation.
Topics: Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Porphyria, Acute Intermittent; Vitamin B 12; Vitamins | 2021 |
Serum pyridoxine, folate, cobalamin, and homocysteine levels in children presenting with vasovagal syncope.
Topics: Adolescent; Blood Pressure Monitoring, Ambulatory; Child; Folic Acid; Homocysteine; Humans; Pyridoxine; Syncope, Vasovagal; Vitamin B 12 | 2022 |
Investigating the causality of metabolites involved in one-carbon metabolism with the risk and age at onset of Parkinson's disease: A two-sample mendelian randomization study.
Topics: Age of Onset; Dietary Supplements; Disease Susceptibility; Folic Acid; Genome-Wide Association Study; Homocysteine; Mendelian Randomization Analysis; Negative Results; Parkinson Disease; Risk; Vitamin B 12; Vitamin B 6 | 2021 |
Letter to the editor regarding megaloblastic anemia with elevated vitamin B12.
Topics: Aged; Anemia, Megaloblastic; Anemia, Pernicious; Folic Acid; Homocysteine; Humans; Injections, Intramuscular; Male; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
Insufficient S-Sulfhydration of Methylenetetrahydrofolate Reductase Contributes to the Progress of Hyperhomocysteinemia.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidation-Reduction; Vitamin B 12 | 2022 |
Effect of nickel on red blood cell parameters and on serum vitamin B12, folate and homocysteine concentrations during pregnancy with and without anemia.
Topics: Anemia; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Nickel; Pregnancy; Vitamin B 12 | 2021 |
Vitamin B12, folate and homocysteine concentrations during pregnancy and early signs of atherosclerosis at school-age.
Topics: Adult; Atherosclerosis; Cardiometabolic Risk Factors; Carotid Intima-Media Thickness; Child; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Male; Maternal Exposure; Maternal Nutritional Physiological Phenomena; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Vitamin B 12 | 2021 |
Prevalence of hyperhomocysteinemia (HHcy) and its major determinants among hypertensive patients over 35 years of age.
Topics: Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Prevalence; Risk Factors; Vitamin B 12 | 2022 |
Association between folic acid, homocysteine, vitamin B12 and erectile dysfunction-A cross-sectional study.
Topics: Cross-Sectional Studies; Erectile Dysfunction; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12 | 2021 |
Genetically predicted circulating homocysteine, vitamin B12, and folate levels and risk of multiple sclerosis: evidence from a two-sample Mendelian randomization analysis.
Topics: Folic Acid; Genome-Wide Association Study; Homocysteine; Humans; Mendelian Randomization Analysis; Multiple Sclerosis; Vitamin B 12 | 2021 |
Variation of homocysteine levels in rheumatoid arthritis patients: relationship to inflammation, cardiovascular risk factors, and methotrexate.
Topics: Adult; Arthritis, Rheumatoid; Cardiovascular Diseases; Creatine; Cross-Sectional Studies; Folic Acid; Heart Disease Risk Factors; Homocysteine; Humans; Inflammation; Male; Methotrexate; Middle Aged; Risk Factors; Vitamin B 12 | 2023 |
The Relationship between Folic Acid and Vitamin B12 Serum Levels with High Sensitivity C-reactive Protein and Homocysteine in Chronic Hemodialysis Patients: A Cross-sectional Study.
Topics: C-Reactive Protein; Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Renal Dialysis; Vitamin B 12 | 2021 |
Methionine synthase deficiency: Variable clinical presentation and benefit of early diagnosis and treatment.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Amino Acid Metabolism, Inborn Errors; Early Diagnosis; Homocysteine; Humans; Metabolism, Inborn Errors; Methionine; Vitamin B 12 | 2022 |
Perspective: The High-Folate-Low-Vitamin B-12 Interaction Is a Novel Cause of Vitamin B-12 Depletion with a Specific Etiology-A Hypothesis.
Topics: Folic Acid; Homocysteine; Humans; Malnutrition; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
Clinical relevance of testing for metabolic vitamin B12 deficiency in patients with polyneuropathy.
Topics: Homocysteine; Humans; Methylmalonic Acid; Polyneuropathies; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
The characteristics of clinical laboratory indicators in anticardiolipin antibody positive cerebral infarction patients.
Topics: Aged; Aged, 80 and over; Antibodies, Anticardiolipin; Blood Coagulation; Blood Platelets; Cerebral Infarction; Clinical Laboratory Techniques; Creatine Kinase; Diabetes Complications; Diabetes Mellitus; Female; Folic Acid; Homocysteine; Humans; Hypertension; Immunity; L-Lactate Dehydrogenase; Lipids; Male; Middle Aged; Thyroid Hormones; Vitamin B 12 | 2022 |
Imbalanced Folate and Vitamin B12 in the Third Trimester of Pregnancy and its Association with Birthweight and Child Growth up to 2 Years.
Topics: Birth Weight; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Pregnancy; Pregnancy Trimester, Third; Vitamin B 12 | 2022 |
The roles of homocysteinemia and methylmalonic acidemia in kidney injury in atypical hemolytic uremic syndrome caused by cobalamin C deficiency.
Topics: Acute Kidney Injury; Amino Acid Metabolism, Inborn Errors; Atypical Hemolytic Uremic Syndrome; Female; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Kidney; Methylmalonic Acid; Oxidoreductases; Thrombotic Microangiopathies; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
5-Methyltetrahydrofolate and Vitamin B12 Supplementation Is Associated with Clinical Pregnancy and Live Birth in Women Undergoing Assisted Reproductive Technology.
Topics: Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Infertility, Female; Live Birth; Pregnancy; Reproductive Techniques, Assisted; Retrospective Studies; Tetrahydrofolates; Vitamin B 12; Vitamin B Complex | 2021 |
Vitamin B
Topics: Creatinine; Homocysteine; Humans; Methylmalonic Acid; Nitrous Oxide; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
Polymorphisms in vitamin B12 and folate metabolising genes and their association with adverse pregnancy outcome: secondary analysis of a population based case control study.
Topics: Case-Control Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Infant; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Pregnancy Outcome; Premature Birth; Vitamin B 12 | 2022 |
One-carbon metabolism during the menstrual cycle and pregnancy.
Topics: Carbon; Estradiol; Female; Folic Acid; Homocysteine; Humans; Menstrual Cycle; Pregnancy; S-Adenosylmethionine; Vitamin B 12 | 2021 |
Plasma homocysteine is associated with nonproliferative retinopathy in patients with type 2 diabetes without renal disease.
Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 2022 |
Reference intervals for plasma vitamin B12 and plasma/serum methylmalonic acid in Danish children, adults and elderly.
Topics: Adult; Aged; Child; Denmark; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Associations of Homocysteine with B Vitamins and Zinc in Serum Levels of Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study.
Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 12; Vitamin B Complex; Zinc | 2021 |
Vitamin B12 levels in patients with retinal vein occlusion and their relation with clinical outcome: a retrospective study.
Topics: Homocysteine; Humans; Retinal Vein Occlusion; Retrospective Studies; Vitamin B 12; Vitamins | 2022 |
Does Metformin Treatment in Pediatric Population Cause Vitamin B12 Deficiency?
Topics: Adolescent; Child; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Male; Metabolic Syndrome; Metformin; Methylmalonic Acid; Prospective Studies; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Folate Deficiency: A Possible Association with Congenital Heart Defects.
Topics: Cross-Sectional Studies; Folic Acid; Folic Acid Deficiency; Heart Defects, Congenital; Homocysteine; Humans; Infant; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
RBC Folate and Serum Folate, Vitamin B-12, and Homocysteine in Chinese Couples Prepregnancy in the Shanghai Preconception Cohort.
Topics: Biomarkers; China; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
Vitamin B12 and chronic kidney disease.
Topics: Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Renal Insufficiency, Chronic; Vitamin B 12 | 2022 |
Influences of Vitamin B
Topics: Aged; Aged, 80 and over; Atrophy; Cognition; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Homocysteine; Humans; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
Breastfed Infants With Spells, Tremor, or Irritability: Rule Out Vitamin B12 Deficiency.
Topics: Breast Feeding; Case-Control Studies; Child; Female; Homocysteine; Humans; Infant; Infant, Newborn; Nitrous Oxide; Seizures; Tremor; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
A Study of Srum Homocysteine Level in Ischaemic Stoke.
Topics: Aged; Homocysteine; Humans; Hyperhomocysteinemia; Ischemia; Ischemic Stroke; Lipids; Risk Factors; Stroke; Vitamin B 12 | 2022 |
A Study on the Levels of Folic Acid, Vitamin B12 and Plasma Homocysteine in Patients with Chronic Kidney Disease.
Topics: Adult; Aged; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Renal Insufficiency, Chronic; Vitamin B 12 | 2022 |
The association between vitamin B12 and plasma homocysteine levels with episodic memory and the volume of memory related brain structures in middle-aged individuals: a retrospective correlational study.
Topics: Adult; Brain; Female; Folic Acid; Homocysteine; Humans; Male; Memory, Episodic; Middle Aged; Retrospective Studies; Vitamin B 12 | 2022 |
Vitamin B12 as a cholinergic system modulator and blood brain barrier integrity restorer in Alzheimer's disease.
Topics: Alzheimer Disease; Blood-Brain Barrier; Cholinergic Agents; Folic Acid; Homocysteine; Humans; Receptors, Cholinergic; Vitamin B 12 | 2022 |
Vitamin B-12 malabsorption and renal function are critical considerations in studies of folate and vitamin B-12 interactions in cognitive performance: NHANES 2011-2014.
Topics: Aged; Cognition; Dietary Supplements; Folic Acid; Homocysteine; Humans; Kidney; Methylmalonic Acid; Nutrition Surveys; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
Muddy water: Additional observational data cannot aid in determining whether there is a physiological interaction between low vitamin B12 and high folate in cognitive health.
Topics: Cognition; Folic Acid; Homocysteine; Humans; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Pregnancy homocysteine and cobalamin status predict childhood metabolic health in the offspring.
Topics: Birth Weight; Child; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Pregnancy; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2023 |
Circulating folate concentrations and the risk of mild cognitive impairment: A prospective study on the older Chinese population without folic acid fortification.
Topics: Aged; Apolipoprotein E4; China; Cognitive Dysfunction; Cohort Studies; Folic Acid; Homocysteine; Humans; Prospective Studies; Vitamin B 12 | 2022 |
Fetal hyperhomocysteinemia is associated with placental inflammation and early breakdown of maternal-fetal tolerance in pre-term birth.
Topics: Biomarkers; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Inflammation; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Placenta; Pregnancy; Premature Birth; Term Birth; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vitamin B 12 | 2022 |
Tetrahydrobiopterin deficiency in schizophrenia: Biochemical and clinical aspects.
Topics: C-Reactive Protein; Case-Control Studies; Folic Acid; Homocysteine; Humans; Phenylketonurias; Schizophrenia; Vitamin B 12 | 2022 |
Vitamin B
Topics: Animals; Fatty Acids; Fibrosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Qa-SNARE Proteins; Vitamin B 12; Vitamins | 2022 |
The association between vitamin B12, folate, homocysteine levels, and carotid intima-media thickness in children with obesity: a cross-sectional study.
Topics: Adolescent; Adult; Carotid Intima-Media Thickness; Child; Child, Preschool; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Insulin Resistance; Obesity; Risk Factors; Vitamin B 12 | 2022 |
Association of methylenetetrahydrofolate reductase
Topics: Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; India; Infant, Newborn; Longitudinal Studies; Methylenetetrahydrofolate Reductase (NADPH2); Parturition; Polymorphism, Genetic; Pregnancy; Pregnant Women; Premature Birth; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Relationships of Serum Homocysteine, Vitamin B
Topics: Case-Control Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Rosacea; Vitamin B 12; Vitamins | 2022 |
Maternal serum concentrations of one-carbon metabolism factors modify the association between biomarkers of arsenic methylation efficiency and birth weight.
Topics: Adult; Arsenic; Arsenicals; Biomarkers; Birth Weight; Carbon; Female; Folic Acid; Homocysteine; Humans; Methylation; Pregnancy; Prenatal Exposure Delayed Effects; Vitamin B 12 | 2022 |
Ischemic Stroke and Dietary Vitamin B12 Deficiency in Old-Aged Females: Impaired Motor Function, Increased Ischemic Damage Size, and Changed Metabolite Profiles in Brain and Cecum Tissue.
Topics: Animals; Brain; Cecum; Diet; Female; Folic Acid; Homocysteine; Ischemic Stroke; Mice; Stroke; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Proton pump inhibitor use and its effect on vitamin B12 and homocysteine levels among men and women: A large cross-sectional study.
Topics: Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Proton Pump Inhibitors; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Association between MTHFR polymorphism and seizure control in epileptic patients with hyperhomocysteinaemia
Topics: Epilepsy; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Seizures; Vitamin B 12; Vitamins | 2022 |
Effect of methylenetetrahydrofolate reductase C677T polymorphism on serum folate but not vitamin B12 levels in patients with H-type hypertension.
Topics: Antihypertensive Agents; Female; Folic Acid; Genotype; Homocysteine; Humans; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12 | 2022 |
Nitrous oxide in labour predicted newborn screening total homocysteine and is a potential risk factor for infant vitamin B12 deficiency.
Topics: Case-Control Studies; Homocysteine; Humans; Infant; Infant, Newborn; Methylmalonic Acid; Neonatal Screening; Nitrous Oxide; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
A Retrospective Study on Clinical Assessment of Cognitive Impairment in a Swedish Cohort: Is There Inequality Between Natives and Foreign-Born?
Topics: Albumins; Alzheimer Disease; Atrophy; Biomarkers; Calcium; Cognitive Dysfunction; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Retrospective Studies; Sweden; Thyrotropin; Vitamin B 12 | 2022 |
One-Carbon Metabolism Biomarkers and Risks of Incident Neurocognitive Disorder among Cognitively Normal Older Adults.
Topics: Aged; Biomarkers; Carbon; Cognitive Dysfunction; Dementia; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 2022 |
An unusual case of subacute combined degeneration due to nitrous oxide abuse, which relapsed after bariatric surgery: A case report.
Topics: Adolescent; Bariatric Surgery; Female; Gait Disorders, Neurologic; Homocysteine; Humans; Nitrous Oxide; Paresthesia; Subacute Combined Degeneration; Vitamin B 12; Vitamin B Complex | 2022 |
Overlapping sperm damages from vitamin B or D deficiency in mice: Insights into the role of clinical supplementations.
Topics: Animals; Body Weight; Dietary Supplements; Folic Acid; Homocysteine; Male; Mice; Semen; Spermatozoa; Vitamin B 12; Vitamins | 2022 |
Clinical features of different stage subacute combined degeneration of the spinal cord.
Topics: Blood Glucose; Cholesterol; Glycated Hemoglobin; Homocysteine; Humans; Retrospective Studies; Sodium Oxybate; Subacute Combined Degeneration; Vitamin B 12 | 2022 |
Maternal Vitamin B
Topics: Child; Female; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Neonatal Screening; Pregnancy; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
Serum Homocysteine, Vitamin B12, Folate, and Their Association with Mild Cognitive Impairment and Subtypes of Dementia.
Topics: Alzheimer Disease; Cognitive Dysfunction; Dementia, Vascular; Folic Acid; Frontotemporal Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12 | 2022 |
Clinical characteristics and genotype analysis of five infants with cblX type of methylmalonic acidemia.
Topics: Acetylcarnitine; Amino Acid Metabolism, Inborn Errors; China; Drug Resistant Epilepsy; Female; Genotype; Homocysteine; Host Cell Factor C1; Humans; Infant; Infant, Newborn; Male; Methylmalonic Acid; Vitamin B 12 | 2022 |
Dietary-derived vitamin B12 protects Caenorhabditis elegans from thiol-reducing agents.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Caenorhabditis elegans; Carbon; Dithiothreitol; Folic Acid; Homocysteine; Hydrogen Sulfide; Ligases; Lipids; Mercaptoethanol; Methionine; Methyltransferases; Nucleic Acids; Oxygen; Reducing Agents; S-Adenosylmethionine; Sulfhydryl Compounds; Vitamin B 12; Vitamins | 2022 |
Simultaneous estimation of total homocysteine and methylmalonic-acid using LC-MS/MS: Clinical application in adult and pediatric.
Topics: Adult; Biomarkers; Child; Chromatography, Liquid; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Pediatrics; Tandem Mass Spectrometry; Vitamin B 12 | 2022 |
Elevated homocysteine levels: What inborn errors of metabolism might we be missing?
Topics: Adult; Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Metabolism, Inborn Errors; Retrospective Studies; Vitamin B 12 | 2023 |
Diagnostic reliability of serum active B12 (holo-transcobalamin) in true evaluation of vitamin B12 deficiency: Relevance in current perspective.
Topics: Biomarkers; Homocysteine; Humans; Reproducibility of Results; Retrospective Studies; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Hearing Function and Nutritional Status in Aviation Pilots from Spain Exposed to High Acoustic Damage.
Topics: Acoustics; Aviation; Biomarkers; Folic Acid; Hearing; Homocysteine; Nutritional Status; Spain; Vitamin B 12; Vitamins | 2022 |
Acquired Vitamin B12 Deficiency in Newborns: Positive Impact on Newborn Health through Early Detection.
Topics: Biomarkers; Early Diagnosis; Female; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant Health; Infant, Newborn; Male; Methylmalonic Acid; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Reduced circulating folate among older adults caused by continuous work: nested cross-sectional study conducted in a country with folic acid fortification program.
Topics: Aged; Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
Inferring causal effects of homocysteine and B-vitamin concentrations on bone mineral density and fractures: Mendelian randomization analyses.
Topics: Bone Density; Female; Fractures, Bone; Genome-Wide Association Study; Homocysteine; Humans; Male; Mendelian Randomization Analysis; Middle Aged; Vitamin B 12; Vitamin B Complex | 2022 |
The role of the deficiency of vitamin B12 and folic acid on homocysteinemia in children with Turner syndrome.
Topics: Child; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Turner Syndrome; Vitamin B 12; Vitamin B 12 Deficiency | 2023 |
The acute postprandial response of homocysteine to multivitamin and mineral supplementation with a standard meal is not impaired in older compared to younger adults.
Topics: Aged; Dietary Supplements; Folic Acid; Homocysteine; Humans; Minerals; Vitamin B 12; Vitamin B Complex | 2023 |
An assessment of serum vitamin B12 and folate in patients with Crohn's disease.
Topics: Crohn Disease; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Pre-natal dietary imbalance of folic acid and vitamin B12 deficiency adversely impacts placental development and fetal growth.
Topics: Animals; Diet; Female; Fetal Development; Fetal Weight; Folic Acid; Homocysteine; Mice; Placenta; Placentation; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency | 2023 |
Association of methylene tetrahydrofolate reductase (MTHFR) gene polymorphisms with serum folate, cobalanin and homocysteine concentrations in Greek adults.
Topics: Adult; Female; Folic Acid; Genotype; Greece; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Vitamin B 12 | 2023 |
Low Magnesium in Conjunction with High Homocysteine and Less Sleep Accelerates Telomere Attrition in Healthy Elderly Australian.
Topics: Aged; Australia; Folic Acid; Homocysteine; Humans; Magnesium; Micronutrients; Sleep; Telomere; Vitamin B 12 | 2023 |
Comparison of blood levels of vitamin B12, folic acid, riboflavin, and homocysteine in keratoconus and healthy subjects.
Topics: Adolescent; Adult; Cross-Sectional Studies; Folic Acid; Healthy Volunteers; Homocysteine; Humans; Keratoconus; Riboflavin; Vitamin B 12; Young Adult | 2023 |
Phenome-wide association study of genetically predicted B vitamins and homocysteine biomarkers with multiple health and disease outcomes: analysis of the UK Biobank.
Topics: Biological Specimen Banks; Biomarkers; Female; Folic Acid; Homocysteine; Humans; Mendelian Randomization Analysis; Pregnancy; United Kingdom; Vitamin A; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin K | 2023 |
Possible Combined Effects of Plasma Folate Levels, Global DNA Methylation, and Blood Cadmium Concentrations on Renal Cell Carcinoma.
Topics: Cadmium; Carcinoma, Renal Cell; Case-Control Studies; DNA Methylation; Folic Acid; Homocysteine; Humans; Kidney Neoplasms; Vitamin B 12; Vitamins | 2023 |
Diagnostic Value of ATG5, Apo-Lipoprotein B-48, Thyroid Hormones, and Homocysteine in Patients with Alzheimer's Disease.
Topics: Aged; Alzheimer Disease; Apolipoprotein B-48; Autophagy-Related Protein 5; Folic Acid; Homocysteine; Humans; Middle Aged; Thyroid Hormones; Vitamin B 12 | 2023 |
Homocysteine exchange across skeletal muscle in patients with chronic kidney disease.
Topics: Folic Acid; Homocysteine; Humans; Muscle, Skeletal; Renal Dialysis; Renal Insufficiency, Chronic; Vitamin B 12 | 2023 |
Use of serum folate and vitamin B
Topics: Coronary Artery Disease; Folic Acid; Homocysteine; Humans; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2023 |
An incorrect cutoff was used, leading to null results.
Topics: Folic Acid; Homocysteine; Humans; Negative Results; Vitamin B 12; Vitamin B 12 Deficiency | 2023 |
Homocysteine serum levels correlate with the number of failed IVF cycles even when within normal range.
Topics: Adult; Embryo Transfer; Female; Fertilization in Vitro; Homocysteine; Humans; Reference Values; Retrospective Studies; Vitamin B 12 | 2023 |
Associations of Homocysteine, Folate, and Vitamin B12 with Osteoarthritis: A Mendelian Randomization Study.
Topics: Female; Folic Acid; Homocysteine; Humans; Mendelian Randomization Analysis; Osteoarthritis; Risk Factors; Vitamin B 12 | 2023 |
Vitamin B6 Levels and Impaired Folate Status but Not Vitamin B12 Associated with Low Birth Weight: Results from the MAASTHI Birth Cohort in South India.
Topics: Birth Cohort; Birth Weight; Female; Folic Acid; Homocysteine; Humans; India; Infant, Low Birth Weight; Infant, Newborn; Pregnancy; Prospective Studies; Pyridoxine; Vitamin B 12; Vitamin B 6 | 2023 |
Evaluation of homocysteine, vitamin, and trace element levels in women with gallstones.
Topics: Copper; Female; Folic Acid; Gallstones; Homocysteine; Humans; Nickel; Selenium; Trace Elements; Vitamin B 12; Vitamins; Zinc | 2023 |
Ischaemic stroke with multi-focal venous and arterial thrombosis due to hyperhomocysteinemia: anabolic androgenic steroid use and MTHFR c.667 C > T variant - a case report.
Topics: Anabolic Androgenic Steroids; Brain Ischemia; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Stroke; Male; Methylenetetrahydrofolate Reductase (NADPH2); Risk Factors; Stroke; Thrombosis; Vitamin B 12 | 2023 |
Association of MTHFR C667T Polymorphism, Homocysteine, and B Vitamins with Senile Cataract.
Topics: Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Vitamin B 12; Vitamin B Complex | 2023 |
Serum vitamin B12 is a promising auxiliary index for the diagnosis of methylmalonic acidemia in children: A single center study in China.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Child; China; Homocysteine; Humans; Vitamin B 12 | 2023 |
The Importance of Serum Homocysteine as a Biomarker in Diabetic and Obese COVID-19 Patients.
Topics: Biomarkers; COVID-19; Diabetes Mellitus; Female; Folic Acid; Homocysteine; Humans; Interleukin-6; Male; Obesity; Vitamin B 12 | 2023 |
High prevalence of vitamin B-12 deficiency before and early after gastrectomy in patients with gastric cancer.
Topics: Anemia, Iron-Deficiency; Gastrectomy; Homocysteine; Humans; Iron Deficiencies; Prevalence; Stomach Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2023 |
Bacteroides ovatus accelerates metformin-induced vitamin B12 deficiency in type 2 diabetes patients by accumulating cobalamin.
Topics: Animals; Diabetes Mellitus, Type 2; Homocysteine; Humans; Metformin; Mice; Vitamin B 12; Vitamin B 12 Deficiency | 2023 |
The Utilization of Serum Folate and Homocysteine Tests and the Prevalence of Folate Deficiency in Reproductive-Age Korean Women during the COVID-19 Pandemic.
Topics: COVID-19; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Pandemics; Prevalence; Republic of Korea; Vitamin B 12; Vitamin B 12 Deficiency | 2023 |
Association of B vitamin intake and total homocysteine levels with all-cause and cause-specific mortality in central obesity.
Topics: Adult; Cause of Death; Folic Acid; Homocysteine; Humans; Middle Aged; Nutrition Surveys; Obesity, Abdominal; Pyridoxine; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2023 |
The association between methylmalonic acid, a biomarker of mitochondria dysfunction, and phenotypic age acceleration: A population-based study.
Topics: Aged; Biomarkers; Cross-Sectional Studies; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Nutrition Surveys; Vitamin B 12; Vitamin B 12 Deficiency | 2024 |
Exploring the Interplay Between Vitamin B
Topics: Biomarkers; Carbon; DNA Methylation; Folic Acid; Homocysteine; Humans; Male; Nutritional Status; Vitamin B 12; Vitamins | 2023 |
Shedding Light on Lysosomal Malondialdehyde Affecting Vitamin B
Topics: Animals; Brain Ischemia; Endothelial Cells; Homocysteine; Lysosomes; Malondialdehyde; Mice; Reperfusion Injury; Vitamin B 12; Vitamins | 2023 |
Neurovascular Correlates of Cobalamin, Folate, and Homocysteine in Dementia.
Topics: Alzheimer Disease; Brain; Brain Ischemia; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Vitamin B 12 | 2023 |
Relationship between Serum Homocysteine Concentration and Dietary Factors in Young Japanese Women.
Topics: Antioxidants; Diet; Dietary Fiber; East Asian People; Female; Folic Acid; Homocysteine; Humans; Vitamin B 12; Vitamins | 2023 |
The association between homocysteine and bacterial vaginosis: results from NHANES 2001-2004.
Topics: Female; Homocysteine; Humans; Nutrition Surveys; Regression Analysis; Vaginosis, Bacterial; Vitamin B 12 | 2023 |