homocysteine has been researched along with uracil in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hutson, NK; Shapiro, SK; Spence, KD | 1 |
| Coetzee, JN; Prozesky, OW | 1 |
| Gaté, L; Machover, D; Tapiero, H; Tew, KD | 1 |
| Cutler, RG; Evans, M; Haughey, N; Kruman, II; Kruman, Y; Kumaravel, TS; Lee, J; Lohani, A; Mattson, MP; Pedersen, WA | 1 |
| Basten, G; Duthie, SJ; Little, J; McConnell, J; Narayanan, S; Piyathilake, CJ; Powers, H; Sharp, L | 1 |
| Hu, ML; Lin, HG; Lin, PY; Yang, TH | 1 |
| Crott, JW; de Boer, SY; Friederich, P; Kampman, E; Keijer, J; Kok, FJ; Mason, JB; Nagengast, FM; Pellis, L; van Bergeijk, JD; van den Donk, M; van Engeland, M | 1 |
| Chanson, A; Ciappio, ED; Crott, JW; DeVos, L; Liu, Z; Mason, JB; Parnell, LD; Tucker, KL | 1 |
| Bell, GW; Cantu, E; Chao, WH; He, T; Jaenisch, R; Linhart, HG; Moran, E; Steine, E; Troen, A | 1 |
| Allen, RH; Gao, D; Girnary, HH; MacFarlane, AJ; Perry, CA; Shane, B; Stabler, SP; Stover, PJ | 1 |
| Austin, RC; Campan, M; Chiang, EP; Cho, RC; Choi, SW; Dickhout, J; Jang, H; Kim, YI; Laird, PW; Lucock, M; Sohn, KJ; Wang, YC; Weisenberger, DJ; Yates, Z | 1 |
| Cao, JM; Cao, Y; Gong, XJ; Guo, J; Guo, M; Li, D; Lun, YZ; Luo, N; Sun, WP; Tian, YJ; Zhou, SS | 1 |
| Chen, YM; Chiang, EP; Lin, WL; Lin, YJ; Tang, FY; Wang, YC | 1 |
| Chiang, EP; Ko, HA; Lin, YJ; Tang, FY; Wang, YC; Wu, MT | 1 |
1 review(s) available for homocysteine and uracil
| Article | Year |
|---|---|
Prevention of pathologies associated with oxidative stress and dietary intake deficiencies: folate deficiency and requirements.
Topics: Animals; Diet; DNA; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipid Peroxidation; Neoplasms; Nutritional Status; Oxidative Stress; Tetrahydrofolate Dehydrogenase; Uracil | 2001 |
1 trial(s) available for homocysteine and uracil
| Article | Year |
|---|---|
Folic acid and vitamin B-12 supplementation does not favorably influence uracil incorporation and promoter methylation in rectal mucosa DNA of subjects with previous colorectal adenomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; DNA Methylation; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Intestinal Mucosa; Male; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Promoter Regions, Genetic; Uracil; Vitamin B 12 | 2007 |
12 other study(ies) available for homocysteine and uracil
| Article | Year |
|---|---|
Sai-1 mutation: saccharomyces cerevisiae: characteristics of inhibition by S-adenosylmethonine and S-adenosylhomocysteine and protection by methionine.
Topics: Adenine; Carbon Isotopes; Cell Fractionation; Enterococcus faecalis; Genetics, Microbial; Homocysteine; Methionine; Mutation; Protein Biosynthesis; RNA; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Uracil | 1972 |
Linked transduction in Proteus mirabilis.
Topics: Arginine; Citrulline; Homocysteine; Methionine; Mutation; Proteus; Radiation Effects; Ultraviolet Rays; Uracil | 1966 |
Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cell Survival; Cells, Cultured; Diet; Disease Models, Animal; DNA Damage; DNA Repair; Folic Acid Deficiency; Hippocampus; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Transgenic; Neurons; Rats; Uracil | 2002 |
Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in vivo.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Colorectal Neoplasms; DNA Damage; DNA Methylation; Erythrocytes; Female; Folic Acid; Genetic Carrier Screening; Genetic Variation; Genotype; Homocysteine; Homozygote; Humans; Isoenzymes; Lymphocytes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk; Scotland; Tetrahydrofolates; Uracil; Vitamin B 12 | 2004 |
Synergistic effects of S-adenosylhomocysteine and homocysteine on DNA damage in a murine microglial cell line.
Topics: Animals; Cell Line; DNA; DNA Damage; DNA Methylation; Drug Synergism; Free Radical Scavengers; Homocysteine; Hydrogen Peroxide; Mice; Microglia; Reactive Oxygen Species; S-Adenosylhomocysteine; Uracil | 2007 |
Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations.
Topics: Aged; Chromosome Aberrations; Cohort Studies; DNA Damage; DNA Methylation; Female; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Male; Membrane Transport Proteins; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Uracil | 2008 |
Folate deficiency induces genomic uracil misincorporation and hypomethylation but does not increase DNA point mutations.
Topics: Animals; CpG Islands; DNA; DNA Methylation; Folic Acid Deficiency; Homocysteine; Lymphoma, Follicular; Mice; Mice, Inbred C57BL; Point Mutation; Uracil; Uracil-DNA Glycosidase | 2009 |
Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism.
Topics: Animals; Animals, Genetically Modified; Biomarkers; DNA; Folic Acid; Formate-Tetrahydrofolate Ligase; Formates; Glycine Hydroxymethyltransferase; Homocysteine; Methylation; Mice; Thymidine Monophosphate; Uracil | 2009 |
The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification.
Topics: Blotting, Western; Breast Neoplasms; Colonic Neoplasms; CpG Islands; DNA Damage; DNA Methylation; Folic Acid; Gene Expression Regulation, Neoplastic; Genotype; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymorphism, Genetic; Risk Factors; Tumor Cells, Cultured; Uracil | 2009 |
Nicotinamide supplementation induces detrimental metabolic and epigenetic changes in developing rats.
Topics: Animals; Betaine; Choline; CpG Islands; Dietary Supplements; DNA; DNA Damage; DNA Methylation; Epigenesis, Genetic; Glucose Intolerance; Homocysteine; Insulin Resistance; Liver; Male; Metabolic Diseases; Niacin; Niacinamide; Oxidative Stress; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Time Factors; Uracil; Vitamin B Complex; Weight Gain | 2013 |
A novel role of the tumor suppressor GNMT in cellular defense against DNA damage.
Topics: Adenosine; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleus; Cells, Cultured; Chromatography, High Pressure Liquid; Dietary Supplements; DNA Damage; DNA Methylation; Female; Fluorescent Antibody Technique, Indirect; Folic Acid; Glycine N-Methyltransferase; Hepatocytes; Homocysteine; Humans; Liver; Liver Neoplasms; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Knockout; Minor Histocompatibility Antigens; Protein Transport; Purines; Pyrimidines; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Uracil | 2014 |
Regulation of Folate-Mediated One-Carbon Metabolism by Glycine N-Methyltransferase (GNMT) and Methylenetetrahydrofolate Reductase (MTHFR).
Topics: Animals; Carbon; DNA Damage; DNA Methylation; Folic Acid; Genotype; Glycine N-Methyltransferase; Hep G2 Cells; Homocysteine; Humans; Liver; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Neoplasms; Nucleotides; Nutritional Status; Purines; S-Adenosylmethionine; Uracil | 2015 |