homocysteine and uracil

homocysteine has been researched along with uracil in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's0 (0.00)18.2507
2000's9 (64.29)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hutson, NK; Shapiro, SK; Spence, KD1
Coetzee, JN; Prozesky, OW1
Gaté, L; Machover, D; Tapiero, H; Tew, KD1
Cutler, RG; Evans, M; Haughey, N; Kruman, II; Kruman, Y; Kumaravel, TS; Lee, J; Lohani, A; Mattson, MP; Pedersen, WA1
Basten, G; Duthie, SJ; Little, J; McConnell, J; Narayanan, S; Piyathilake, CJ; Powers, H; Sharp, L1
Hu, ML; Lin, HG; Lin, PY; Yang, TH1
Crott, JW; de Boer, SY; Friederich, P; Kampman, E; Keijer, J; Kok, FJ; Mason, JB; Nagengast, FM; Pellis, L; van Bergeijk, JD; van den Donk, M; van Engeland, M1
Chanson, A; Ciappio, ED; Crott, JW; DeVos, L; Liu, Z; Mason, JB; Parnell, LD; Tucker, KL1
Bell, GW; Cantu, E; Chao, WH; He, T; Jaenisch, R; Linhart, HG; Moran, E; Steine, E; Troen, A1
Allen, RH; Gao, D; Girnary, HH; MacFarlane, AJ; Perry, CA; Shane, B; Stabler, SP; Stover, PJ1
Austin, RC; Campan, M; Chiang, EP; Cho, RC; Choi, SW; Dickhout, J; Jang, H; Kim, YI; Laird, PW; Lucock, M; Sohn, KJ; Wang, YC; Weisenberger, DJ; Yates, Z1
Cao, JM; Cao, Y; Gong, XJ; Guo, J; Guo, M; Li, D; Lun, YZ; Luo, N; Sun, WP; Tian, YJ; Zhou, SS1
Chen, YM; Chiang, EP; Lin, WL; Lin, YJ; Tang, FY; Wang, YC1
Chiang, EP; Ko, HA; Lin, YJ; Tang, FY; Wang, YC; Wu, MT1

Reviews

1 review(s) available for homocysteine and uracil

ArticleYear
Prevention of pathologies associated with oxidative stress and dietary intake deficiencies: folate deficiency and requirements.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2001, Volume: 55, Issue:7

    Topics: Animals; Diet; DNA; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipid Peroxidation; Neoplasms; Nutritional Status; Oxidative Stress; Tetrahydrofolate Dehydrogenase; Uracil

2001

Trials

1 trial(s) available for homocysteine and uracil

ArticleYear
Folic acid and vitamin B-12 supplementation does not favorably influence uracil incorporation and promoter methylation in rectal mucosa DNA of subjects with previous colorectal adenomas.
    The Journal of nutrition, 2007, Volume: 137, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; DNA Methylation; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Intestinal Mucosa; Male; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Promoter Regions, Genetic; Uracil; Vitamin B 12

2007

Other Studies

12 other study(ies) available for homocysteine and uracil

ArticleYear
Sai-1 mutation: saccharomyces cerevisiae: characteristics of inhibition by S-adenosylmethonine and S-adenosylhomocysteine and protection by methionine.
    Journal of bacteriology, 1972, Volume: 110, Issue:3

    Topics: Adenine; Carbon Isotopes; Cell Fractionation; Enterococcus faecalis; Genetics, Microbial; Homocysteine; Methionine; Mutation; Protein Biosynthesis; RNA; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Uracil

1972
Linked transduction in Proteus mirabilis.
    Nature, 1966, Mar-19, Volume: 209, Issue:5029

    Topics: Arginine; Citrulline; Homocysteine; Methionine; Mutation; Proteus; Radiation Effects; Ultraviolet Rays; Uracil

1966
Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Mar-01, Volume: 22, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cell Survival; Cells, Cultured; Diet; Disease Models, Animal; DNA Damage; DNA Repair; Folic Acid Deficiency; Hippocampus; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Transgenic; Neurons; Rats; Uracil

2002
Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in vivo.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Colorectal Neoplasms; DNA Damage; DNA Methylation; Erythrocytes; Female; Folic Acid; Genetic Carrier Screening; Genetic Variation; Genotype; Homocysteine; Homozygote; Humans; Isoenzymes; Lymphocytes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk; Scotland; Tetrahydrofolates; Uracil; Vitamin B 12

2004
Synergistic effects of S-adenosylhomocysteine and homocysteine on DNA damage in a murine microglial cell line.
    Clinica chimica acta; international journal of clinical chemistry, 2007, Volume: 379, Issue:1-2

    Topics: Animals; Cell Line; DNA; DNA Damage; DNA Methylation; Drug Synergism; Free Radical Scavengers; Homocysteine; Hydrogen Peroxide; Mice; Microglia; Reactive Oxygen Species; S-Adenosylhomocysteine; Uracil

2007
Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations.
    The American journal of clinical nutrition, 2008, Volume: 88, Issue:4

    Topics: Aged; Chromosome Aberrations; Cohort Studies; DNA Damage; DNA Methylation; Female; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Male; Membrane Transport Proteins; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Uracil

2008
Folate deficiency induces genomic uracil misincorporation and hypomethylation but does not increase DNA point mutations.
    Gastroenterology, 2009, Volume: 136, Issue:1

    Topics: Animals; CpG Islands; DNA; DNA Methylation; Folic Acid Deficiency; Homocysteine; Lymphoma, Follicular; Mice; Mice, Inbred C57BL; Point Mutation; Uracil; Uracil-DNA Glycosidase

2009
Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism.
    The Journal of biological chemistry, 2009, Jan-16, Volume: 284, Issue:3

    Topics: Animals; Animals, Genetically Modified; Biomarkers; DNA; Folic Acid; Formate-Tetrahydrofolate Ligase; Formates; Glycine Hydroxymethyltransferase; Homocysteine; Methylation; Mice; Thymidine Monophosphate; Uracil

2009
The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification.
    International journal of cancer, 2009, May-01, Volume: 124, Issue:9

    Topics: Blotting, Western; Breast Neoplasms; Colonic Neoplasms; CpG Islands; DNA Damage; DNA Methylation; Folic Acid; Gene Expression Regulation, Neoplastic; Genotype; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymorphism, Genetic; Risk Factors; Tumor Cells, Cultured; Uracil

2009
Nicotinamide supplementation induces detrimental metabolic and epigenetic changes in developing rats.
    The British journal of nutrition, 2013, Volume: 110, Issue:12

    Topics: Animals; Betaine; Choline; CpG Islands; Dietary Supplements; DNA; DNA Damage; DNA Methylation; Epigenesis, Genetic; Glucose Intolerance; Homocysteine; Insulin Resistance; Liver; Male; Metabolic Diseases; Niacin; Niacinamide; Oxidative Stress; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Time Factors; Uracil; Vitamin B Complex; Weight Gain

2013
A novel role of the tumor suppressor GNMT in cellular defense against DNA damage.
    International journal of cancer, 2014, Feb-15, Volume: 134, Issue:4

    Topics: Adenosine; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleus; Cells, Cultured; Chromatography, High Pressure Liquid; Dietary Supplements; DNA Damage; DNA Methylation; Female; Fluorescent Antibody Technique, Indirect; Folic Acid; Glycine N-Methyltransferase; Hepatocytes; Homocysteine; Humans; Liver; Liver Neoplasms; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Knockout; Minor Histocompatibility Antigens; Protein Transport; Purines; Pyrimidines; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Uracil

2014
Regulation of Folate-Mediated One-Carbon Metabolism by Glycine N-Methyltransferase (GNMT) and Methylenetetrahydrofolate Reductase (MTHFR).
    Journal of nutritional science and vitaminology, 2015, Volume: 61 Suppl

    Topics: Animals; Carbon; DNA Damage; DNA Methylation; Folic Acid; Genotype; Glycine N-Methyltransferase; Hep G2 Cells; Homocysteine; Humans; Liver; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Neoplasms; Nucleotides; Nutritional Status; Purines; S-Adenosylmethionine; Uracil

2015