homocysteine has been researched along with triiodothyronine in 312 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 71 (22.76) | 18.7374 |
| 1990's | 36 (11.54) | 18.2507 |
| 2000's | 88 (28.21) | 29.6817 |
| 2010's | 99 (31.73) | 24.3611 |
| 2020's | 18 (5.77) | 2.80 |
| Authors | Studies |
|---|---|
| Aakvaag, A; Aanderud, S; Ericsson, UB; Lien, EA; Nedrebø, BG; Nygård, O; Refsum, H; Ueland, PM | 1 |
| Bicíková, M; Hill, M; Putz, Z; Tallová, J; Tomandl, J; Vañuga, A | 1 |
| Atabek, ME; Erkul, I; Pirgon, O | 1 |
| Garrow, TA; Schalinske, KL; Tanghe, KA | 1 |
| Akgul, EO; Beyhan, Z; Bilgi, C; Cakir, E; Erbil, MK; Erturk, K; Ozcan, O; Yaman, H | 1 |
| Gannon, MC; Nuttall, FQ | 1 |
| Bastemir, M; Enli, Y; Evrengul, H; Kaftan, A; Kilic, A; Kilic, M; Kuru, O; Seleci, D; Tanriverdi, H | 1 |
| Aral, Y; Cakal, B; Cakal, E; Demirbaş, B; Karaahmetoğlu, S; Ozkaya, M; Serter, R | 1 |
| Bukhari, SA; Ibrahim, Z; Jalal, F; Nagra, SA; Rajoka, MI; Rana, SM | 1 |
| Bai, F; Hong, B; Ma, SG; Xu, W; Yang, LX | 1 |
| Moraes, BS; Moraes, Rd; Tibiriçá, E; Van Bavel, D | 1 |
| Adamek, Ł; Gołyńska, M; Gołyński, M; Krumrych, W; Kurek, Ł; Lutnicki, K; Sitkowski, Ł; Szczepanik, M; Wilkołek, P | 1 |
| Han, A; Kwon, YH; Won, SB | 1 |
| Liu, J; Wang, G; Wang, Q; Zhang, L; Zhang, N; Zhao, J | 1 |
| Ding, X; Liu, J; Wang, G; Wang, Y | 1 |
| Bashir, N; Kakaraparthi, VN; Mir, MA; Zaman, FA; Zaman, GS | 1 |
| McCully, KS; Tzanakakis, GN; Vezeridis, MP | 1 |
| Borst, MM; Coenen, HH; Deussen, A; Feinendegen, LE; Hamacher, K; Henrich, M; Herzog, H; Schrader, J; Stöcklin, G | 1 |
| Loscalzo, J; Stamler, JS | 1 |
| Carney, DF; Papadimitriou, JC; Shin, ML | 1 |
| Amato, A; Civello, IM; De Giovanni, L; Fregnan, GB; Murari, G; Rabitti, C; Sovera, A | 1 |
| Andersson, A; Brattström, L; Hultberg, B; Isaksson, A; Israelsson, B | 1 |
| Djurhuus, R; Mansoor, MA; Svardal, AM; Ueland, PM | 1 |
| Jakubowski, H | 23 |
| Fraher, LJ; McFadden, RG | 1 |
| Ariyoshi, S; Fujisue, T; Ichida, S; Yoshioka, K | 1 |
| Greene, JL; Grunbaum, Z; Krohn, KA; Kroll, K; Rasey, JS | 1 |
| Benyon, RC; Church, MK; Holgate, ST | 2 |
| Levy, HL; Matorin, AI; Mudd, SH | 1 |
| McCully, KS | 1 |
| Hua, P; Nuske, JH | 1 |
| McCully, KS; Vezeridis, MP | 2 |
| DeMeester, CA; Pike, MC | 1 |
| Henson, PM; Riches, DW; Stanworth, DR; Watkins, JL | 1 |
| Llanos, MN; Pino, AM; Ronco, AM; Valladares, LE | 1 |
| Pike, MC; Snyderman, R | 2 |
| Aultman, M; Gerrard, TL; Kaplan, AM; Squire, C; Strawson, J | 1 |
| Bowman, BJ; Smith, RJ; Speziale, SC; Ulrich, RG | 1 |
| Bienvenue, A; Philippot, J; Sainte-Marie, J; Vidal, M | 1 |
| Braun, DE; Freed, WJ | 1 |
| Djurhuus, R; Lillehaug, JR; Male, R; Svardal, AM; Ueland, PM | 1 |
| Campochiaro, PA; Hackett, SF | 1 |
| Ariyoshi, S; Ichida, S; Okazaki, Y; Sobue, K; Tanaka, T; Yoshioka, K | 1 |
| Heike, T; Katamura, K; Kubota, M; Mikawa, H; Shinomiya, K | 1 |
| Ariyoshi, S; Ichida, S; Moriyama, M; Yoshioka, K | 1 |
| Carvalho, AC; McCully, KS | 1 |
| Ariyoshi, S; Ichida, S; Oda, Y; Oka, H; Yoshioka, K | 1 |
| de Weck-Gaudard, D; Fern, EB; Finot, PA; Hunt, M | 1 |
| Ichida, S | 1 |
| Clarke, S; Lou, LL | 1 |
| Silverstein, SC; Sung, SJ | 1 |
| Samet, MK | 1 |
| Archer, S; Chan, VL; Ho, JH; Juranka, PF | 1 |
| Drautz, H; Jizba, JV; Sedmera, P; Vanek, Z; Zähner, H | 1 |
| Brovold, AB; Hetland, O; Prydz, H | 1 |
| Loo, G; Smith, JT | 1 |
| Achterberg, PW; de Jong, JW; de Tombe, PP; Harmsen, E | 1 |
| Salama, AI; Saller, CF | 1 |
| Boyko, ER; Carpenter, GB; McCully, KS | 1 |
| Chet, I; Lisker, N; Paster, N | 1 |
| Freed, WJ; Hoffer, BJ; Wuerthele, SE; Yasuda, RP | 1 |
| Chiang, PK; Morita, Y; Siraganian, RP | 1 |
| Morita, Y; Siraganian, RP | 1 |
| Ahl, R | 1 |
| Evensen, SA; Galdal, KS; Lyberg, T; Nilsen, E; Prydz, H | 1 |
| Carson, DA; Kamatani, N | 1 |
| Mizel, D; Pick, E | 1 |
| Hattori, H; Kanfer, JN | 1 |
| Gebhart, E | 1 |
| Porta, R; Schatz, RA; Sellinger, OZ; Wilens, TE | 1 |
| Rutledge, CO; Samet, MK | 1 |
| Barber, JR; Clarke, S | 1 |
| Carson, DA; Kamatani, N; Willis, EH | 1 |
| Jaiswal, RK; Landon, EJ; Sastry, BV | 1 |
| Gregor, P; Schatz, RA; Sellinger, OZ; Tatter, SB; Wilens, TE | 1 |
| Chignard, M; Dray, F; Lecompte, T; Randon, J; Vargaftig, BB | 1 |
| Dewhurst, IC; Griffiths, R; Hagan, JJ; Morris, RG | 1 |
| Fox, IH; Palella, TD; Schatz, RA; Wilens, TE | 1 |
| Dudman, NP; Wilcken, DE | 1 |
| Reddy, GS; Wilcken, DE | 1 |
| Hoffman, RM; Mecham, JO; Stern, PH | 1 |
| Meizel, S | 1 |
| Schatz, RA; Sellinger, OZ; Wilens, TE | 1 |
| Gebhart, E; Kappauf, H | 1 |
| Bynum, JW | 1 |
| McGee, R; Rabe, CS; Williams, TP | 1 |
| Ali-Osman, F; Chin, L; Dwyer-Hansen, L; Grunbaum, Z; Krohn, KA; Livesey, J; Nelson, N; Rasey, JS; Spence, AM; Stein, D | 1 |
| Frauscher, G; Hoeger, H; Karnaukhova, E; Lubec, B; Muehl, A | 1 |
| Kroll, K; Martin, GV | 1 |
| Chen, H; McLennan, AG | 1 |
| Fredholm, BB; Lindström, K; Lloyd, HG | 1 |
| Goldman, E; Jakubowski, H | 1 |
| Sciotti, VM; Van Wylen, DG | 1 |
| Aarbakke, J; Endresen, PC; Kildalsen, H; Loennechen, T | 1 |
| Carotti, D; Lucarelli, M; Palitti, F; Scarpa, S; Strom, R | 1 |
| Ratashak, SA; Rosenquist, TH; Selhub, J | 1 |
| Matthews, JH | 1 |
| Deussen, A; Flesche, CW; Loncar, R | 1 |
| Abraham, AK; Antonio, CM; Nunes, MC; Refsum, H | 1 |
| Kagan, HM; Liu, G; Nellaiappan, K | 1 |
| Ferguson, E; Joseph, J; Kalyanaraman, B; Parthasarathy, S | 1 |
| Blom, HJ; Boers, GH; Fritzer-Szekeres, M; Lubec, B; Szekeres, T | 1 |
| Getoff, N; Lubec, G; Solar, S | 1 |
| Antholine, WE; Ferguson, E; Hogg, N; Joseph, J; Kalyanaraman, B; Parthasarathy, S; Singh, RJ | 1 |
| Ashizawa, K; Miyamoto, M; Tsuzuki, Y | 1 |
| Goodrich-Blair, H; Kolter, R | 1 |
| Aviv, A; Bardeguez, A; Jakubowski, H; Zhang, L | 1 |
| Barthe, C; Belloc, F; Bernard, P; Bihlou-Nabera, C; Boisseau, MR; Marit, G; Mercié, P; Pruvost, A; Renard, M; Seigneur, M | 1 |
| Ambrosius, WT; Jakubowski, H; Pratt, JH | 1 |
| Belloc, F; Boisseau, RM; Closse, C; Durrieu, F; Garnier, O; Lascoste, L; Marit, G; Mercié, P; Renard, M | 1 |
| Huang, RF; Huang, SM; Lin, BS; Liu, TZ; Wei, JS | 1 |
| Najib, S; Sánchez-Margalet, V | 2 |
| Fischer, JA; McCann, MP; Snetselaar, KM | 1 |
| DiBello, PM; Jacobsen, DW; Ketterer, ME; Majors, AK; Sengupta, S; Wehbe, C | 1 |
| Mukai, Y; Ohata, K; Suzuki, T; Tanabe, S; Togawa, T | 1 |
| Bakhtiar, R; Hop, CE | 1 |
| Hanyu, N; Motomiya, Y; Okabe, H; Uji, Y; Ukaji, F | 1 |
| Wu, JT; Wu, LL | 1 |
| Huang, RF; Huang, SM; Hung, CY; Lin, BS; Lu, HT | 1 |
| Cole, DE; Cuthbert, C; Daneshvar, P; Yazdanpanah, M | 1 |
| Bacchetti, T; Curatola, G; Ferretti, G; Marotti, E | 1 |
| TRUTSCHEL, W | 1 |
| ABADI, DM; WILCOX, PE | 1 |
| FRAENZ, J; KIRNBERGER, EJ; KLEMM, D; KOCH, R; WOLF, V | 1 |
| LEUKERT, G; ZICHA, L | 1 |
| SCHUNK, J | 1 |
| LUDWIG, EH; TYNDALL, RL | 1 |
| FREITAS, PA | 1 |
| MEHES, J; MOLNAR, Z; VARGA, F | 1 |
| TARVER, H; VIRUPAKSHA, TK | 1 |
| Chavarría, T; Martínez-Poveda, B; Medina, MA; Quesada, AR; Sánchez-Jiménez, F | 1 |
| Kazimir, M; Wilson, FR | 1 |
| Kamudhamas, A; Nelson, DM; Pang, L; Sadovsky, Y; Smith, SD | 1 |
| Bacchetti, T; Curatola, G; Ferretti, G; Mazzanti, L; Nanetti, L; Vignini, A | 1 |
| Chwatko, G; Jakubowski, H | 2 |
| Klevay, LM | 3 |
| Bełtowski, J | 1 |
| Chen, Z; Gao, Y; Hui, R; Liu, Y; Song, L; Wang, J; Xu, H; Yang, X; Yang, Y; Zhen, Y; Zhou, J | 1 |
| Garel, J; Tawfik, DS | 1 |
| Hoffman, M; Lenkowski, A; Lockhart, E; Sauls, DL; Warren, ME; Wilhelm, SE | 1 |
| Flatt, PR; McClenaghan, NH; Patterson, S | 2 |
| Bald, E; Turski, WA | 1 |
| Chuniaud, L; Kerkeni, M; Maaroufi, K; Miled, A; Tnani, M; Trivin, F | 1 |
| Endo, N; Kanouchi, H; Nishiyama, K; Oka, T; Otsuka, A; Taga, M | 1 |
| Bacchetti, T; Ferretti, G; Mazzanti, L; Moroni, C; Nanetti, L; Rabini, RA; Vignini, A | 1 |
| Au, AL; Chan, MS; Chan, SW; Kwan, YW; Seto, SW | 1 |
| Darvesh, S; Martin, E; Walsh, R | 1 |
| Daniels, R; De Keersmaecker, SC; De Vos, DE; Habel, LW; Janssens, JC; Metzger, K; Ptacek, D; Vanderleyden, J; Verhoeven, T | 1 |
| Brandsch, C; Dinger, C; Eder, K; Hirche, F; Stangl, GI; Weisse, K | 1 |
| Cui, RZ; Li, Y; Li, YL; Qin, Q; Wang, H; Zhao, BR; Zhao, FM | 1 |
| Jakubowski, H; Perła-Kaján, J; Twardowski, T | 1 |
| Boers, GH; Chwatko, G; Jakubowski, H; Shih, DM; Strauss, KA | 1 |
| Jakubowski, H; Kaján, L; Marczak, Ł; Perła-Kaján, J; Skowronek, P; Twardowski, T | 1 |
| Jakubowski, H; Sikora, M; Twardowski, T | 1 |
| Liu, LY; Liu, YH; Song, T; Wu, SJ; You, Y | 1 |
| Fletcher, KA; Gates, AT; Lowry, M; Murugeshu, A; Robinson, JW; Rusin, O; Strongin, RM; Warner, IM | 1 |
| Toohey, JI | 2 |
| Gugliucci, A | 1 |
| Fakayode, SO; Ganea, GM; Gates, AT; Lowry, M; Murugeshu, A; Robinson, JW; Strongin, RM; Warner, IM | 1 |
| Zimny, J | 1 |
| Vos, E | 1 |
| Huang, CC; Tseng, WL | 1 |
| Boers, GH; Jakubowski, H; Strauss, KA | 1 |
| Dou, J; Gu, W; Lu, J; Meng, J; Mu, Y; Pan, C; Yang, G | 1 |
| Djuric, D; Hrncić, D; Macut, D; Radosavljević, T; Rasić-Marković, A; Stanojlović, O; Susić, V | 1 |
| Kedzierska, M; Olas, B; Wachowicz, B | 1 |
| Lynch, SM | 1 |
| Badiou, S; Cristol, JP; Dupuy, AM; Durant, R; Jaussent, A; Jeandel, C; Morena, M; Picot, MC; Ventura, E | 1 |
| Karolczak, K; Olas, B | 1 |
| Cabrera, RM; Finnell, RH; Gupta, S; Jakubowski, H; Kraus, JP; Kruger, WD; Perla-Kaján, J; Shih, DM; Wang, H | 1 |
| Colović, M; Djuric, D; Hrncić, D; Krstić, D; Radosavljević, T; Rasić-Marković, A; Stanojlović, O; Susić, V | 1 |
| Jakubowski, H; Sikora, M | 1 |
| Kedzierska, M; Kołodziejczyk, J; Olas, B; Rywaniak, J; Wachowicz, B | 1 |
| de Andrade, CR; de Oliveira, AM; Eberlin, MN; Haddad, R; Iyomasa, MM; Ramalho, LN; Tirapelli, CR; Uyemura, SA | 1 |
| Clarke, SG; Gomez, T; Khare, S; Linster, CL | 1 |
| Djuric, D; Hrncić, D; Krstić, D; Macut, D; Rasić-Marković, A; Stanojlović, O | 1 |
| Jakubowski, H; Perla-Kaján, J | 1 |
| Beltowski, J; Jakubowski, H; Wójcicka, G | 1 |
| Brkić, P; Djuric, D; Djuro, M; Hrncić, D; Loncar-Stevanović, H; Mladenović, D; Rasić-Marković, A; Stanojević, I; Stanoljović, O; Vucević, D | 1 |
| Callegher, E; Millioni, R; Puricelli, L; Seraglia, R; Tessari, P; Vettore, M | 1 |
| Belló-Klein, A; Candido, GO; D'Almeida, V; Irigoyen, MC; Jacob, MH; Mendes, RH; Mostarda, C; Ribeiro, MF; Rigatto, K; Salemi, VM; Sirvente, RA | 1 |
| Li, G; Liu, T; Yang, J; Zhao, J; Zhu, W | 1 |
| Angayarkanni, N; Barathi, S; Dhupper, M; Muralidharan, C; Natarajan, SK; Pasupathi, A; Pukraj, R; Sivashanmugham, M; Velpandian, T | 1 |
| Kołodziejczyk, J; Malinowska, J; Olas, B | 1 |
| Ishimine, N; Kurihara, Y; Matsuda, K; Nakamura, K; Nogi, S; Okumura, N; Sumida, T; Tozuka, M; Usami, Y; Yamauchi, K | 1 |
| Bayrak, A; Bayrak, T; Demirpençe, E; Kilinç, K | 2 |
| Morakinyo, MK; Simoyi, RH; Strongin, RM | 1 |
| Malinowska, J; Olas, B; Rywaniak, J | 1 |
| Carru, C; Deiana, L; Pisanu, E; Sanna, M; Sati, S; Scanu, B; Sengupta, S; Sotgia, S; Zinellu, A | 1 |
| Collins, P; Cooney, MT; Graham, IM; Mayne, P; McGarrigle, SA; Monavari, A; Moran, N; O'Neill, S; Walsh, GM | 1 |
| Malinowska, J; Nowak, P; Olas, B | 1 |
| Erler, J; Kołodziejczyk, J; Malinowska, J; Olas, B; Oleszek, W; Stochmal, A | 1 |
| Jakubowski, H; Marczak, L; Sikora, M; Stobiecki, M | 1 |
| Djurić, D; Hrnčić, D; Lončar-Stevanović, H; Macut, D; Rašić-Marković, A; Stanojlović, O | 1 |
| Malinowska, J; Olas, B | 2 |
| Jalili, S; Moosavi-Movahedi, AA; Papari, MM; Yousefi, R | 1 |
| Djuric, D; Hrnčić, D; Macut, D; Marković, AR; Stanojlović, O | 1 |
| Chang, HH; Chen, BY; Chen, YS; Lin, DP; Lin, W; Liu, HJ; Teng, MC; Tsao, ZJ | 1 |
| Głowacki, R; Jakubowski, H | 1 |
| Kolodziejczyk-Czepas, J; Nowak, P; Olas, B; Talar, B; Wachowicz, B | 1 |
| Borowczyk, K; Jakubowski, H; Tisończyk, J | 1 |
| Babicz, K; Malinowska, J; Olas, B; Oleszek, W; Stochmal, A | 1 |
| Borowczyk, K; Jakubowski, H; Shih, DM | 1 |
| Djuric, D; Hrncić, D; Krstić, D; Macut, D; Rasić-Marković, A; Stanojlović, O; Susić, V | 1 |
| Kolodziejczyk, J; Malinowska, J; Olas, B | 1 |
| Alavi, P; Jalili, S; Moosavi-Movahedi, AA; Yousefi, R | 1 |
| Malinowska, J; Olas, B; Tomczynska, M | 1 |
| Jakubowski, H; Perła-Kaján, J | 1 |
| Malinowska, J; Olas, B; Oleszek, W; Stochmal, A | 1 |
| Barudzic, N; Djordjevic, D; Djuric, D; Jakovljevic, V; Vuletic, M; Zivkovic, V | 1 |
| Kowalska, I; Kołodziejczyk-Czepas, J; Malinowska, J; Moniuszko-Szajwaj, B; Olas, B; Oleszek, W; Stochmal, A | 1 |
| Juntapram, K; Muangsin, N; Praphairaksit, N; Siraleartmukul, K | 1 |
| Khazaei, S; Moosavi-Movahedi, AA; Yousefi, R | 1 |
| Bjekić-Macut, J; Djuric, D; Hrncić, D; Rasić-Marković, A; Stanojlović, O; Susić, V | 1 |
| Djuric, D; Hrnčić, D; Macut, D; Rašić-Marković, A; Stanojlović, O; Šušić, V | 1 |
| Bharathselvi, M; Biswas, J; Coral, K; Narayanasamy, A; Ramakrishnan, S; Selvi, R; Sulochana, KN | 1 |
| Bretes, E; Zimny, J | 1 |
| Colovic, M; Djuric, D; Hrncic, D; Krstic, D; Lekovic, J; Macut, D; Rasic-Markovic, A; Stanojlovic, O; Susic, V | 1 |
| Arora, B; Halder, N; Narayanasamy, A; Nirmal, J; Patnaik, S; Ravi, AK; Velpandian, T | 1 |
| Muangsin, N; Pengpong, T; Sangvanich, P; Sirilertmukul, K | 1 |
| Barudzic, N; Djuric, DM; Jakovljevic, V; Joksimovic, J; Pechanova, O; Selakovic, D; Srejovic, I; Zivkovic, V | 1 |
| Castañon, M; Genoud, V; Lauricella, AM; Quintana, I | 1 |
| Genoud, V; Kordich, LC; Lauricella, AM; Quintana, I | 1 |
| Chivangkul, T; Muangsin, N; Padungros, P; Pengprecha, S; Prasongsuk, S; Siraleartmukul, K | 1 |
| Furmaniak, P; Głowacki, R; Kubalczyk, P | 1 |
| Asriyantz, RA; Gaillard, C; Haertlé, T; Muronetz, VI; Semenyuk, PI; Stroylova, YY | 1 |
| Casas, M; de Paz, MV; Ferris, C; Jiménez-Castellanos, MR; Lucero, MJ | 1 |
| Kumar, T; Sharma, GS; Singh, LR | 2 |
| Barudzic, N; Djuric, DM; Jakovljevic, V; Radovanovic, A; Srejovic, I; Stanojlovic, O; Zivkovic, V | 1 |
| Gao, X; Ge, B; Meng, M; Wu, S; Yang, S; Yang, X | 1 |
| Dai, W; Li, P; Liu, LY; Tu, JH; Wang, SX; Yang, XH; Yin, YL | 1 |
| Kontek, B; Olas, B | 1 |
| Gurda, D; Handschuh, L; Jakubowski, H; Kotkowiak, W | 1 |
| Chen, J; Gao, J; Xu, L; Yang, P; Yu, H | 1 |
| Adamcikova, Z; Kruzliak, P; Smith, RM; Zulli, A | 1 |
| Djuric, D; Kipenko, AV; Krylov, BV; Lopatina, EV; Pasatetskaya, NA; Penniyaynen, VA | 1 |
| Dar, TA; Kumar, T; Sharma, GS; Singh, LR | 1 |
| Akulov, AE; Chubarov, AS; Godovikova, TS; Knorre, DG; Koptyug, IV; Koval, OA; Razumov, IA; Romaschenko, AV; Zakharova, OD; Zavjalov, EL | 1 |
| Hajjari, S; Hemmateenejad, B; Javadi, S; Masoudi, R; Yousefi, R | 1 |
| Arru, D; Carru, C; Cossu, A; Giordo, R; Mangoni, AA; Pintus, G; Posadino, AM; Scanu, B; Sotgia, S; Zinellu, A | 1 |
| Aitken, RJ; Baker, MA; Connaughton, H; Flanagan, HM; Hedges, A; Whiting, S | 1 |
| Fang, L; He, C; Li, H; Li, X; Liu, N; Sun, X; Wang, J; Yang, Z | 1 |
| Cárdenas, C; Díaz-Santiago, E; Medina, MÁ; Quesada, AR; Rodríguez-Caso, L; Serrano, JJ | 1 |
| Costa, LG; Furlong, CE; Jarvik, GP; Marsillach, J | 1 |
| Sawasdee, P; Tep-areenan, P; Wetchasit, P | 1 |
| Bełtowski, J; Pastryk, JE; Rusek, M | 1 |
| Jakubowski, H; Malinowska, A; Perła-Kajan, J; Rusek, M; Sitkiewicz, E; Utyro, O | 1 |
| Bartosik-Psujek, H; Bełtowski, J; Jamroz-Wiśniewska, A; Rejdak, K; Wójcicka, G | 1 |
| He, XD; Huang, L; Li, Y; Mei, XY; Nie, J; Qi, DS; Si, W; Zhao, SM | 1 |
| Khoshaman, K; Kurganov, BI; Moafian, Z; Oryan, A; Yousefi, R | 1 |
| Bharathselvi, M; Biswas, S; Coral, K; Narayanansamy, A; Ramakrishnan, S; Raman, R; Selvi, R; Sulochana, KN | 1 |
| Gluszek, J; Oszkinis, G; Pawlak, AL; Radziemski, A; Strauss, E; Supinski, W | 1 |
| Sharma, GS; Singh, LR | 1 |
| Aydın, AF; Doğru-Abbasoğlu, S; Kondakçı, G; Uysal, M | 1 |
| Baldessari, A; Genoud, V; Gionco, S; Quintana, I; Quintana, PG | 1 |
| Bollinger, KE; Cui, X; Kaidery, NA; Navneet, S; Smith, SB; Thomas, B; Wang, J; Yoon, Y; Zhao, J | 1 |
| Kontek, B; Olas, B; Oleszek, W; Stochmal, A | 1 |
| Chamorro, ME; Maltaneri, RE; Nesse, AB; Schiappacasse, A; Vittori, DC; Wetzler, DE | 1 |
| Bai, B; Cao, H; Ding, G; Huo, J; Mei, X; Qiu, Z; Wan, C; Wang, H; Wang, L; Wang, S; Wang, Z; Wu, J; Xie, Q; Zhang, M; Zhang, Q; Zhang, T; Zhao, J; Zhao, S | 1 |
| Bełtowski, J; Gałczyński, K; Nowakowski, Ł; Rechberger, T; Semczuk, A; Vasilevska, D | 1 |
| Borowczyk, K; Chwatko, G; Głowacki, R; Kubalczyk, P; Piechocka, J; Wrońska, M | 1 |
| Blackwell, HE; Boursier, ME; Combs, JB | 1 |
| Chen, N; Qiao, Z; Wang, C | 1 |
| Basak, T; Carru, C; Ray, A; Sabareesh, V; Sengupta, S; Silla, Y; Varshney, S; Zinellu, A | 1 |
| AnandBabu, K; Angayarkanni, N; Sen, P | 1 |
| Głowacki, R; Kośka, I; Kubalczyk, P; Olejarz, P; Purgat, K | 1 |
| Borowczyk, K; Gątarek, P; Głowacki, R; Kałużna-Czaplińska, J; Rosiak, A | 1 |
| Angelovski, G; Bowman, MK; Chubarov, A; Dobrynin, S; Gatilov, Y; Kirilyuk, I; Krumkacheva, O; Kutseikin, S; Morozov, D; Silnikov, V; Spitsyna, A | 1 |
| Chwatko, G; Głowacki, R; Jakubowski, H; Piechocka, J; Wrońska, M | 1 |
| Bavec, A; Goličnik, M; Taler-Verčič, A | 1 |
| Armstrong, DW; Krupčík, J; Májek, P; Portillo, AE; Šimon, P; Špánik, I | 1 |
| Hadwan, MH; Obeid, NJ | 1 |
| Ahn, JS; Jang, JH; Jang, JP; Ko, SK; Kwon, MC; Nogawa, T; Osada, H; Takahashi, S | 1 |
| Ghosh, S; Koren, TDT | 1 |
| Tsiasioti, A; Tzanavaras, PD; Zacharis, CK | 1 |
| Jakubowski, H; Perła-Kaján, J; Sikora, M; Skrzydlewski, P | 1 |
| Gupta, A; Kumari, K; Sharma, GS; Singh, KS; Singh, LR | 1 |
| Boudreault, PL; Comeau, C; Firdaus, SB; Klarskov, K; Komba, JE; Loubane, G; Naylor, S; Robert, G; Venne, P; Wagner, JR | 1 |
23 review(s) available for homocysteine and triiodothyronine
| Article | Year |
|---|---|
Homocysteine thiolactone: metabolic origin and protein homocysteinylation in humans.
Topics: Animals; Autoradiography; Cells, Cultured; Homocysteine; Humans; Radiation-Protective Agents | 2000 |
Protein N-homocysteinylation: implications for atherosclerosis.
Topics: Arteriosclerosis; Cardiovascular Diseases; Endothelium, Vascular; Homocysteine; Humans; Methionine; Models, Biological; Proteins | 2001 |
Hyperhomocysteinemia is a risk factor for cancer and a new potential tumor marker.
Topics: Biomarkers, Tumor; Homocysteine; Humans; Hyperhomocysteinemia; Neoplasms; Oxidative Stress; Risk Factors | 2002 |
Homocysteine-thiolactone and S-nitroso-homocysteine mediate incorporation of homocysteine into protein in humans.
Topics: Animals; Endothelium, Vascular; Homocysteine; Humans; Protein Binding; Proteins | 2003 |
Molecular basis of homocysteine toxicity in humans.
Topics: Homocysteine; Humans; Proteins | 2004 |
Ischemic heart disease as deficiency disease.
Topics: Animals; Aryldialkylphosphatase; Catalysis; Collagen; Coronary Artery Disease; Cross-Linking Reagents; Dietary Supplements; Elastin; Glucose; Heart Diseases; Homocysteine; Humans; Hydrolysis; Lipid Metabolism; Myocardial Ischemia; Vitamins | 2004 |
Protein homocysteinylation: a new mechanism of atherogenesis?
Topics: Animals; Atherosclerosis; Homocysteine; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Liver | 2005 |
[Molecular mechanisms of biotoxicity of homocysteine--facts and hypotheses].
Topics: Animals; Arginine; Atherosclerosis; Homocysteine; Humans; Hydrolysis; Methylation; Nitric Oxide; Oxidative Stress | 2005 |
Mechanisms of homocysteine toxicity in humans.
Topics: Animals; Aryldialkylphosphatase; Hemostasis; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Inflammation; Lipoproteins, HDL; Lipoproteins, LDL; Protein-Lysine 6-Oxidase; Proteins | 2007 |
[The role of homocysteine thiolactone in some of human diseases].
Topics: Animals; Aryldialkylphosphatase; Atherosclerosis; Biomarkers; Fibrinogen; Folic Acid; Homocysteine; Humans; Lipoproteins, HDL; Rabbits; Stroke; Vitamin B 12; Vitamin B 6 | 2006 |
How dietary deficiency, genes and a toxin can cooperate to produce arteriosclerosis and ischemic heart disease.
Topics: Animals; Arteriosclerosis; Aryldialkylphosphatase; Collagen; Copper; Diet; Elastin; Heart Diseases; Homocysteine; Humans; Malnutrition; Myocardial Ischemia | 2006 |
The molecular basis of homocysteine thiolactone-mediated vascular disease.
Topics: Fibrinogen; Homocysteine; Humans; Immunity, Innate; Proteins; Vascular Diseases | 2007 |
Dehydroascorbic acid as an anti-cancer agent.
Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Dehydroascorbic Acid; Homocysteine; Humans; Methionine; Mice; Neoplasms | 2008 |
[Mechanisms that protect against homocysteine toxicity].
Topics: Aryldialkylphosphatase; Cardiovascular Diseases; Cysteine Endopeptidases; Homocysteine; Humans; Hydrolases; Hydrolysis | 2008 |
Mechanism of action of homocysteine and its thiolactone in hemostasis system.
Topics: Animals; Blood Platelets; Endothelial Cells; Hemostasis; Homocysteine; Humans | 2009 |
The pathophysiological hypothesis of homocysteine thiolactone-mediated vascular disease.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Cystathionine beta-Synthase; Fibrinogen; Homocysteine; Humans; Hyperhomocysteinemia; Methionine-tRNA Ligase; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Thrombosis; Vascular Diseases | 2008 |
The role of paraoxonase 1 in the detoxification of homocysteine thiolactone.
Topics: Animals; Aryldialkylphosphatase; Autoimmunity; Fibrinogen; Homocysteine; Humans; Immune System; Methionine-tRNA Ligase; Mice; Mice, Transgenic; Models, Biological; Risk Factors; Thrombosis | 2010 |
Quality control in tRNA charging -- editing of homocysteine.
Topics: Amino Acyl-tRNA Synthetases; Animals; Brain Diseases; Catalytic Domain; Escherichia coli; Homocysteine; Humans; Hydrolysis; Hyperhomocysteinemia; Substrate Specificity; Transfer RNA Aminoacylation; Vascular Diseases | 2011 |
Chemical biology of homocysteine thiolactone and related metabolites.
Topics: Amyloid; Animals; Brain Diseases; Cardiovascular Diseases; Dipeptides; Homocysteine; Humans; Methionine; Methionine-tRNA Ligase; Mice; Protein Biosynthesis; Proteins; Proteolysis | 2011 |
The disturbance of hemostasis induced by hyperhomocysteinemia; the role of antioxidants.
Topics: Animals; Antioxidants; Blood Platelets; Blood Vessels; Endothelial Cells; Fibrinolysis; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia | 2012 |
Paraoxonase 1 and homocysteine metabolism.
Topics: Alzheimer Disease; Animals; Aryldialkylphosphatase; Atherosclerosis; Coronary Artery Disease; Diabetes Mellitus; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipoproteins, HDL; Mice; Oxidative Stress; Stroke | 2012 |
Protein N-homocysteinylation: From cellular toxicity to neurodegeneration.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Homocysteine; Humans; Neurodegenerative Diseases; Neurons; Prions; Protein Aggregates | 2015 |
The Structure and Function of Paraoxonase-1 and Its Comparison to Paraoxonase-2 and -3.
Topics: Amino Acid Sequence; Animals; Arachidonic Acid; Aryldialkylphosphatase; Carboxylic Ester Hydrolases; Catalytic Domain; Homocysteine; Humans; Mice; Protein Binding; Protein Conformation; Sequence Alignment; Substrate Specificity | 2020 |
3 trial(s) available for homocysteine and triiodothyronine
| Article | Year |
|---|---|
The metabolic response to a high-protein, low-carbohydrate diet in men with type 2 diabetes mellitus.
Topics: Aged; Aged, 80 and over; Aldosterone; Diabetes Mellitus, Type 2; Diet, Carbohydrate-Restricted; Dietary Carbohydrates; Dietary Proteins; Homocysteine; Human Growth Hormone; Humans; Hydrocortisone; Insulin-Like Growth Factor I; Male; Middle Aged; Thyrotropin; Thyroxine; Triiodothyronine | 2006 |
Lack of gastric adverse effects of erdosteine in rats and men.
Topics: Administration, Oral; Aged; Animals; Carbocysteine; Female; Gastric Mucosa; Homocysteine; Humans; Male; Middle Aged; Peptic Ulcer; Rats; Rats, Inbred Strains; Thioglycolates; Thiophenes; Tiopronin | 1991 |
Homocysteine thiolactone contributes to the prognostic value of fibrin clot structure/function in coronary artery disease.
Topics: Coronary Artery Disease; Fibrin; Folic Acid; Homocysteine; Humans; Myocardial Infarction; Prognosis; Risk Factors; Thrombosis; Vitamin B 12; Vitamin B Complex | 2022 |
286 other study(ies) available for homocysteine and triiodothyronine
| Article | Year |
|---|---|
Plasma total homocysteine levels in hyperthyroid and hypothyroid patients.
Topics: Adult; Aged; Arteriosclerosis; Cardiovascular Diseases; Cholesterol; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Multivariate Analysis; Risk Factors; Thyroxine; Triiodothyronine; Vitamin B 12 | 1998 |
Effect of treatment of hypothyroidism on the plasma concentrations of neuroactive steroids and homocysteine.
Topics: Adjuvants, Immunologic; Adult; Aged; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Homocysteine; Humans; Hypothyroidism; Male; Microsomes; Middle Aged; Pregnanolone; Pregnenolone; Progesterone; Thyrotropin; Thyroxine; Time Factors; Triiodothyronine | 2001 |
Plasma homocysteine concentrations in adolescents with subclinical hypothyroidism.
Topics: Adolescent; Cholesterol; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypothyroidism; Isoantibodies; Kidney; Kidney Function Tests; Thyroiditis, Autoimmune; Thyrotropin; Thyroxine; Triiodothyronine; Vitamin B 12 | 2003 |
Triiodothyronine treatment attenuates the induction of hepatic glycine N-methyltransferase by retinoic acid and elevates plasma homocysteine concentrations in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Enzyme Induction; Glycine N-Methyltransferase; Homocysteine; Hyperthyroidism; Hypothyroidism; Liver; Male; Methyltransferases; Rats; Rats, Sprague-Dawley; Tretinoin; Triiodothyronine | 2004 |
The effects of thyroxine replacement on the levels of serum asymmetric dimethylarginine (ADMA) and other biochemical cardiovascular risk markers in patients with subclinical hypothyroidism.
Topics: Adolescent; Adult; Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Enzyme Inhibitors; Female; Homocysteine; Hormone Replacement Therapy; Humans; Hypothyroidism; Lipoproteins, HDL; Lipoproteins, LDL; Middle Aged; Nitric Oxide; Risk Factors; Thyrotropin; Thyroxine; Triiodothyronine | 2005 |
Interaction of plasma homocysteine and thyroid hormone concentrations in the pathogenesis of the slow coronary flow phenomenon.
Topics: Aged; Angina Pectoris; Blood Flow Velocity; Case-Control Studies; Coronary Angiography; Coronary Circulation; Endothelium, Vascular; Female; Homocysteine; Humans; Male; Middle Aged; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine | 2007 |
Homocysteine and fibrinogen changes with L-thyroxine in subclinical hypothyroid patients.
Topics: Adult; Case-Control Studies; Female; Fibrinogen; Folic Acid; Homocysteine; Humans; Hypothyroidism; Kidney; Middle Aged; Thyrotropin; Thyroxine; Triiodothyronine; Vitamin B 12 | 2007 |
Oxidative stress elevated DNA damage and homocysteine level in normal pregnant women in a segment of Pakistani population.
Topics: Adult; Aspartate Aminotransferases; Body Temperature; Cholesterol; Cross-Sectional Studies; DNA Damage; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Immunoenzyme Techniques; Oxidative Stress; Pakistan; Pregnancy; Thyroxine; Triiodothyronine | 2011 |
Ischemia-modified albumin in patients with hyperthyroidism and hypothyroidism.
Topics: Adult; Antithyroid Agents; Autoantibodies; Biomarkers; C-Reactive Protein; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Female; Homocysteine; Humans; Hyperthyroidism; Hypothyroidism; Iodide Peroxidase; Male; Methimazole; Middle Aged; Oxidative Stress; Serum Albumin; Serum Albumin, Human; Thyroxine; Triglycerides; Triiodothyronine | 2012 |
Effects of dietary creatine supplementation on systemic microvascular density and reactivity in healthy young adults.
Topics: Adult; Capillaries; Cholesterol; Cholesterol, LDL; Creatine; Creatinine; Diet; Homocysteine; Humans; Male; Microvessels; Skin; Thyroxine; Triiodothyronine; Uric Acid; Vasodilation; Young Adult | 2014 |
Relationship between Total Homocysteine, Folic Acid, and Thyroid Hormones in Hypothyroid Dogs.
Topics: Animals; Case-Control Studies; Dog Diseases; Dogs; Female; Folic Acid; Homocysteine; Hypothyroidism; Male; Thyroid Hormones; Thyroxine; Triiodothyronine | 2017 |
Different Effects of Maternal Low-Isoflavone Soy Protein and Genistein Consumption on Hepatic Lipid Metabolism of 21-Day-Old Male Rat Offspring.
Topics: Adiponectin; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Blood Glucose; Caseins; Cholesterol; Dietary Supplements; Fatty Acids, Nonesterified; Female; Genistein; Homocysteine; Insulin; Isoflavones; Lipid Metabolism; Liver; Male; Maternal Nutritional Physiological Phenomena; PPAR alpha; Pregnancy; Rats; Rats, Sprague-Dawley; Soybean Proteins; Triglycerides; Triiodothyronine | 2017 |
Cerebrovascular risk factors associated with ischemic stroke in a young non-diabetic and non-hypertensive population: a retrospective case-control study.
Topics: Adult; Case-Control Studies; Cholesterol, HDL; Female; Homocysteine; Humans; Incidence; Ischemic Stroke; Male; Middle Aged; Neutrophils; Retrospective Studies; Risk Factors; Triiodothyronine | 2020 |
Impaired Sensitivity to Thyroid Hormones Is Associated With Elevated Homocysteine Levels in the Euthyroid Population.
Topics: Adult; Congenital Hypothyroidism; Homocysteine; Humans; Receptors, Thyrotropin; Thyroid Function Tests; Thyroid Hormone Resistance Syndrome; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine | 2022 |
Comparison of Creatine Kinase-MB, Troponin-I, Troponin-T, Triiodothyronine, Thyroxine, Apoprotein-B and Homocysteine between Non-smokers, Smokers at High Altitudes, and Smokers at Sea Level.
Topics: Altitude; Apoproteins; Creatine Kinase, MB Form; Homocysteine; Humans; Non-Smokers; Thyroxine; Triiodothyronine; Troponin I; Troponin T | 2023 |
Effect of the synthetic N-homocysteine thiolactonyl derivatives, thioretinaco, thioretinamide, and thioco on growth and lactate production by malignant cells.
Topics: Antineoplastic Agents; Cell Division; Cells, Cultured; Fibroblasts; Homocysteine; Humans; Lactates; Lactic Acid; Tretinoin; Tumor Cells, Cultured; Vitamin B 12 | 1992 |
Noninvasive assessment of regional cardiac adenosine using positron emission tomography.
Topics: Adenosine; Animals; Carbon Radioisotopes; Dogs; Energy Metabolism; Homocysteine; Myocardial Ischemia; Tissue Distribution; Tomography, Emission-Computed | 1992 |
Capillary zone electrophoretic detection of biological thiols and their S-nitrosated derivatives.
Topics: Bradykinin; Cysteine; Cystine; Disulfides; Electrodes; Electrophoresis; Glutathione; Homocysteine; Homocystine; Nitrosation; Sulfhydryl Compounds | 1992 |
Inhibitors of membrane lipid metabolism enhance complement-mediated nucleated cell killing through distinct mechanisms.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acylation; Adenine; Adenosine; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Complement C9; Complement Membrane Attack Complex; Complement System Proteins; Cytotoxicity, Immunologic; Flow Cytometry; Homocysteine; Immunosuppressive Agents; L-Lactate Dehydrogenase; Membrane Lipids; Methylation; Mice; Thimerosal | 1991 |
Influence of hydrolysis on plasma homocysteine determination in healthy subjects and patients with myocardial infarction.
Topics: Adult; Aged; Chromatography, Ion Exchange; Female; Homocysteine; Homocystine; Humans; Hydrolysis; Male; Middle Aged; Myocardial Infarction | 1991 |
Modulation of glutathione content and the effect on methionine auxotrophy and cellular distribution of homocysteine and cysteine in mouse cell lines.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cell Division; Cell Line; Culture Media; Cystamine; Cysteamine; Cysteine; Fibroblasts; Glutathione; Homocysteine; Intracellular Fluid; Leukemia, Experimental; Methionine; Methionine Sulfoximine; Mice | 1991 |
Proofreading in vivo: editing of homocysteine by methionyl-tRNA synthetase in the yeast Saccharomyces cerevisiae.
Topics: Autoradiography; Chromatography, Thin Layer; Genotype; Homocysteine; Kinetics; Methionine-tRNA Ligase; Mutagenesis, Site-Directed; Plasmids; Saccharomyces cerevisiae; Sulfur Radioisotopes | 1991 |
Inhibitors of membrane transmethylation reactions prevent the lymphocyte chemokinetic response.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Bradykinin; Chemotaxis, Leukocyte; Colchicine; Homocysteine; Humans; Interleukin-16; Leukocytes, Mononuclear; Lymphocytes; Lymphokines; Male; Membrane Lipids; Methylation; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Second Messenger Systems | 1990 |
Proofreading in vivo: editing of homocysteine by methionyl-tRNA synthetase in Escherichia coli.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Escherichia coli; Homocysteine; Kinetics; Methionine-tRNA Ligase; Mutation; Plasmids; Sulfates; Sulfur Radioisotopes | 1990 |
Enhancement by L-methionine on the contractile response of uterine segments to acetylcholine and high KCl is mainly due to enhancement of Ca uptake.
Topics: Acetylcholine; Animals; Calcium; Female; Homocysteine; In Vitro Techniques; Methionine; Potassium Chloride; Pregnancy; Rats; Tubercidin; Uterine Contraction; Uterus | 1990 |
Synthesis and radiobiological applications of [35S]L-homocysteine thiolactone.
Topics: Animals; Brain; Ferrets; Homocysteine; Isotope Labeling; Male; Mice; Mice, Inbred C3H; Myocardium; Neoplasms, Experimental; Oxygen; Rabbits; Radiation-Protective Agents; Sulfur Radioisotopes; Tissue Distribution | 1990 |
IgE-dependent activation of mast cells is not associated with enhanced phospholipid methylation.
Topics: Animals; Cyclic AMP; Histamine Release; Homocysteine; Immunoglobulin E; In Vitro Techniques; Male; Mast Cells; Methionine; Methylation; Phosphatidylserines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Tritium; Tubercidin | 1986 |
IgE-dependent activation of human lung mast cells is not associated with increased phospholipid methylation.
Topics: Antibodies, Anti-Idiotypic; Calcimycin; Cyclic AMP; Histamine Release; Homocysteine; Humans; Immunoglobulin E; Lung; Mast Cells; Methylation; Phospholipids; Tubercidin | 1988 |
Homocysteine thiolactone: failure to detect in human serum or plasma.
Topics: Adult; Aged; Child, Preschool; Chromatography; Female; Homocysteine; Humans; Hydrolysis; Infant; Male; Middle Aged | 1989 |
Homocysteinemia and arteriosclerosis: failure to isolate homocysteine thiolactone from plasma and lipoproteins.
Topics: Arteriosclerosis; Emphysema; Homocysteine; Humans; Lipoproteins | 1989 |
Invertebrate phototransduction: involvement of cytoskeletal elements.
Topics: Animals; Astacoidea; Cattle; Colchicine; Cytoskeleton; Fibroblasts; Homocysteine; Horseshoe Crabs; Invertebrates; Isomerism; Membrane Potentials; Methyltransferases; Photoreceptor Cells; Retina; S-Adenosylhomocysteine; Signal Transduction; Tubercidin | 1989 |
Histopathological effects of homocysteine thiolactone on epithelial and stromal tissues.
Topics: Administration, Topical; Animals; Blood Vessels; Epithelium; Female; Fibrosis; Homocysteine; Injections, Intramuscular; Injections, Intraperitoneal; Kidney; Liver; Mice; Mice, Inbred A; Muscles; Necrosis; Skin | 1989 |
Inhibition of phosphoinositide metabolism in human polymorphonuclear leukocytes by S-adenosylhomocysteine.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Homocysteine; Humans; In Vitro Techniques; Kinetics; Neutrophils; Phosphatidylinositols; S-Adenosylhomocysteine; Type C Phospholipases | 1988 |
Regulation of macrophage lysosomal secretion by adenosine, adenosine phosphate esters, and related structural analogues of adenosine.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Esterases; Homocysteine; Kinetics; Lysosomes; Macrophages; Male; Mice; Receptors, Cell Surface; Receptors, Purinergic; Secretory Rate; Structure-Activity Relationship; Theophylline; Tubercidin | 1985 |
The transmethylations inhibitor 3-deazaadenosine, inhibits in vitro testosterone production by rat testis interstitial cells stimulated with HCG.
Topics: Animals; Bucladesine; Chorionic Gonadotropin; Drug Synergism; Homocysteine; Leydig Cells; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, LH; Ribonucleosides; Testosterone; Tubercidin | 1985 |
Regulation of mononuclear leukocyte function by transmethylation reactions.
Topics: Animals; Cell Migration Inhibition; Enzyme Activation; Guinea Pigs; Homocysteine; Macrophages; Methylation; Oxygen; Phospholipases; S-Adenosylmethionine; Superoxides | 1985 |
Role of adenosine deaminase in human monocyte differentiation and tumor cell cytotoxicity.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Antibody-Dependent Cell Cytotoxicity; Carcinoma, Transitional Cell; Cell Differentiation; Cell Line; Cytotoxicity, Immunologic; Homocysteine; Humans; Lymphokines; Macrophage Activation; Monocytes; Nucleoside Deaminases; Phagocytosis; Superoxides; Urinary Bladder Neoplasms | 1985 |
Characteristics of aggregated immunoglobulin G as an immunologic phagocytic stimulus for granule enzyme release from human neutrophils.
Topics: Calcium; Calcium Channel Blockers; Cycloheximide; Cytoplasmic Granules; Dose-Response Relationship, Drug; Exocytosis; Homocysteine; Humans; Immunoglobulin G; Magnesium; Muramidase; Neutrophils; Peroxidase; Phagocytosis; Secretory Rate; Tubercidin | 1986 |
Thiolation of low-density lipoproteins and their interaction with L2C leukemic lymphocytes.
Topics: Animals; Cell Line; Guinea Pigs; Homocysteine; Humans; Kinetics; Leukemia, Experimental; Lipoproteins, LDL; Lymphocytes; Microscopy, Electron; Receptors, LDL | 1986 |
Anticonvulsant activity of deaminated analogues of glutamic acid diethyl ester (GDEE).
Topics: Animals; Anticonvulsants; Female; Glutamates; Glutarates; Homocysteine; Mice; Pentylenetetrazole; Seizures | 1988 |
Growth support and toxicity of homocysteine and its effects on methionine metabolism in non-transformed and chemically transformed C3H/10T1/2 cells.
Topics: Animals; Cell Division; Cell Line; Cysteine; Dose-Response Relationship, Drug; Glutathione; Homocysteine; Homocystine; Methionine; Mice; Mice, Inbred C3H; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1988 |
Homocysteine thiolactone in arteriosclerosis and cancer.
Topics: Adenocarcinoma; Adult; Aged; Arteriosclerosis; Chromatography, Ion Exchange; Chromatography, Thin Layer; Colonic Neoplasms; Female; Homocysteine; Humans; Male; Middle Aged; Myocardial Infarction; Neoplasms; Thymoma; Thymus Neoplasms | 1988 |
Implication of protein carboxymethylation in retinal pigment epithelial cell chemotaxis.
Topics: Adenine; Adenosine; Chemotaxis; Eye Proteins; Fibronectins; Homocysteine; Humans; Hydrolysis; Methanol; Pigment Epithelium of Eye; Platelet-Derived Growth Factor; Protein Methyltransferases; Protein O-Methyltransferase | 1988 |
General characteristics of the superprecipitation reaction of rat crude uterine myosin B: effects of L-methionine and/or transmethylation blockers on the reaction.
Topics: Animals; Chemical Precipitation; Chickens; Electrophoresis, Polyacrylamide Gel; Female; Homocysteine; Methionine; Methylation; Myosins; Rats; Rats, Inbred Strains; Tubercidin; Uterus | 1987 |
Inhibitor of 2', 5'-oligoadenylate synthetase induced in human T lymphoblastoid cell line treated with deoxyadenosine, deoxycoformycin and interferon.
Topics: 2',5'-Oligoadenylate Synthetase; Adenosine; Cell Line; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Enzyme Induction; Homocysteine; Humans; Interferon Type I; Pentostatin; Ribonucleosides; T-Lymphocytes; Vidarabine | 1986 |
Enhancement by L-methionine of contractile responses to acetylcholine and high KCl in uterine segment.
Topics: Acetylcholine; Animals; Calcium; Female; Homocysteine; In Vitro Techniques; Methionine; Methyltransferases; Muscle, Smooth; Ovariectomy; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylethanolamine N-Methyltransferase; Potassium Chloride; Protein O-Methyltransferase; Rats; Tubercidin; Uterine Contraction; Uterus | 1987 |
Homocysteine thiolactone, N-homocysteine thiolactonyl retinamide, and platelet aggregation.
Topics: Adenosine Triphosphate; Blood Platelets; Collagen; Homocysteine; Humans; In Vitro Techniques; Platelet Aggregation; Prostaglandins; Tretinoin | 1987 |
L-methionine enhances the contractile response to norepinephrine of rat vas deferens.
Topics: Animals; Calcium; Female; Guinea Pigs; Homocysteine; In Vitro Techniques; Male; Methionine; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rats; Rats, Inbred Strains; Tubercidin; Vas Deferens | 1987 |
Dietary substitution of methionine by its precursors: influence on body growth of rats.
Topics: Animals; Diet; Growth; Homocysteine; Homocystine; Methionine; Rats | 1987 |
L-methionine enhances the contractile responses of rat uterine smooth muscle to acetylcholine and high KCl.
Topics: Acetylcholine; Animals; Calcium Chloride; Female; Homocysteine; In Vitro Techniques; Methionine; Methylation; Phospholipids; Potassium Chloride; Proteins; Rats; Rats, Inbred Strains; Tubercidin; Uterine Contraction | 1986 |
Carboxyl methylation of human erythrocyte band 3 in intact cells. Relation to anion transport activity.
Topics: Adenosine; Anion Exchange Protein 1, Erythrocyte; Anions; Biological Transport; Cycloleucine; Erythrocytes; Homocysteine; Humans; Methylation; Phosphates | 1986 |
Inhibition of macrophage phagocytosis by methylation inhibitors. Lack of correlation of protein carboxymethylation and phospholipid methylation with phagocytosis.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cells, Cultured; Deoxyadenosines; Homocysteine; Kinetics; Macrophages; Methylation; Mice; Phagocytosis; Phospholipids; Proteins; Vidarabine | 1985 |
Inhibition of antibody production by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Antibody Formation; B-Lymphocytes; Cells, Cultured; DNA Replication; Homocysteine; Immunosuppressive Agents; Lymphocyte Activation; Male; Methylation; Mice; S-Adenosylmethionine | 1985 |
An analysis of multiple mechanisms of adenosine toxicity in baby hamster kidney cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cell Adhesion; Cell Line; Coformycin; Drug Resistance; Drug Synergism; Guinea Pigs; Homocysteine; Kidney; Nucleotides; Pentostatin; Ribonucleotide Reductases; S-Adenosylhomocysteine; Uridine | 1985 |
Two thiolactones from Streptomyces Tü 2476.
Topics: Homocysteine; Lactones; Streptomyces | 1985 |
Inhibitory effect of 3-deazaadenosine on the thromboplastin response of stimulated human monocytes.
Topics: Dose-Response Relationship, Drug; Homocysteine; Humans; In Vitro Techniques; Methylation; Monocytes; Phytohemagglutinins; Ribonucleosides; Thromboplastin; Tubercidin | 1985 |
Effect of S-adenosylhomocysteine on sulfhydryl xenobiotic transmethylases in rat liver.
Topics: Animals; Homocysteine; Liver; Male; Methyltransferases; Microsomes, Liver; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1985 |
Myocardial S-adenosylhomocysteine hydrolase is important for adenosine production during normoxia.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Coronary Disease; Homocysteine; Hydrolases; In Vitro Techniques; Kinetics; Male; Myocardium; Perfusion; Rats; Rats, Inbred Strains | 1985 |
Inhibition of protein carboxylmethylation and dopamine autoreceptor functioning.
Topics: Animals; Apomorphine; Corpus Striatum; Dopamine; Homocysteine; Male; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; Sulpiride; Synaptosomes | 1985 |
Homocysteine thiolactone perchlorate: X-ray crystallography of a lipophilic salt.
Topics: Crystallization; Homocysteine; X-Ray Diffraction | 1985 |
Effects of cysteine and structurally related compounds on ochratoxin production by Aspergillus ochraceus.
Topics: Aspergillus; Aspergillus ochraceus; Cysteine; Cystine; Ethionine; Glutathione; Homocysteine; Hydrogen-Ion Concentration; Methionine; Ochratoxins | 1985 |
The effect of local application of homocysteine on neuronal activity in the central nervous system of the rat.
Topics: Animals; Betaine; Brain; Convulsants; Electrophysiology; Glutamates; Glutamic Acid; Homocysteine; Male; Neurons; Rats; Rats, Inbred Strains | 1982 |
Effect of inhibitors of transmethylation on histamine release from human basophils.
Topics: Adenine; Adenosine; Basophils; Calcimycin; Histamine Release; Homocysteine; Humans; Immunoglobulin E; In Vitro Techniques; Methylation; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1981 |
Inhibition of IgE-mediated histamine release from rat basophilic leukemia cells and rat mast cells by inhibitors of transmethylation.
Topics: Adenine; Adenosine; Animals; Basophils; Female; Histamine Release; Homocysteine; Immunoglobulin E; Leukemia; Mast Cells; Methylation; Mice; Rabbits; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1981 |
Effect of inhibitors of methylation on early and late interferon synthesis in bovine kidney cell cultures.
Topics: Adenine; Adenosine; Animals; Cattle; Cells, Cultured; Cycloheximide; Cycloleucine; Homocysteine; Interferons; Methylation; Newcastle disease virus; Poly I-C; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Inhibition of the thromboplastin response of endothelial cells in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium; Endotoxins; Gallic Acid; Homocysteine; Humans; In Vitro Techniques; Tetradecanoylphorbol Acetate; Thromboplastin; Tubercidin | 1984 |
Differential cyst(e)ine requirements in human T and B lymphoblastoid cell lines.
Topics: B-Lymphocytes; Cell Line; Concanavalin A; Cystathionine; Cysteine; Cystine; Herpesvirus 4, Human; Homocysteine; Humans; Lymphocyte Activation; Staphylococcal Protein A; T-Lymphocytes | 1982 |
Role of transmethylation in the elicitation of an oxidative burst in macrophages.
Topics: Adenosine; Animals; Concanavalin A; Depression, Chemical; Guinea Pigs; Homocysteine; Lectins; Macrophage Activation; Macrophages; Methylation; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Oxygen; Superoxides; Tubercidin; Wheat Germ Agglutinins | 1982 |
Inhibition of rat brain microsomal Na+,K+-ATPase by S-adenosylmethionine.
Topics: Animals; Brain; Homocysteine; Lipid Metabolism; Methylation; Microsomes; Rats; S-Adenosylmethionine; Sodium-Potassium-Exchanging ATPase; Tubercidin | 1984 |
The action of anticlastogens on chemically induced SCE.
Topics: beta-Aminoethyl Isothiourea; Cells, Cultured; Chromosomes; Cysteine; Homocysteine; Humans; Lymphocytes; Mutagens; Mutation; Oxyquinoline; Sister Chromatid Exchange; Triaziquone | 1984 |
Brain methylation and epileptogenesis: the case of methionine sulfoximine.
Topics: Adenosine; Animals; Brain; Epilepsy; Histamine; Homocysteine; Methionine; Methionine Sulfoximine; Methylation; Methylhistamines; Mice; Nerve Tissue Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Correlations between phospholipid methylation and neuronal catecholamine transport.
Topics: Adenine; Adenosine; Animals; Biological Transport; Cerebral Cortex; Cytosol; Homocysteine; Kinetics; Male; Membrane Lipids; Methylation; Norepinephrine; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; Synaptosomes | 1984 |
Inhibition of protein carboxyl methylation by S-adenosyl-L-homocysteine in intact erythrocytes. Physiological consequences.
Topics: Adenosine; Aspartic Acid; Erythrocyte Membrane; Erythrocytes; Homocysteine; Humans; Membrane Proteins; Methionine; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Selection and characterization of a murine lymphoid cell line partially deficient in S-adenosylhomocysteine hydrolase.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cell Line; Cell Separation; Clone Cells; Homocysteine; Hydrolases; Lymphoma; Mice; S-Adenosylhomocysteine; T-Lymphocytes | 1983 |
Methylation of phospholipids in microsomes of the rat aorta.
Topics: Animals; Aorta, Thoracic; Chromatography, Thin Layer; Fluorescence Polarization; Homocysteine; Male; Methylation; Microsomes; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Trypsin; Type C Phospholipases | 1983 |
Possible role of increased brain methylation in methionine sulfoximine epileptogenesis: effects of administration of adenosine and homocysteine thiolactone.
Topics: Adenosine; Animals; Brain; Brain Chemistry; Histamine; Homocysteine; Methionine Sulfoximine; Methylation; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Phospholipids; Reaction Time; Seizures | 1983 |
Transmethylation reactions are required for initial morphologic and biochemical responses of human monocytes to chemoattractants.
Topics: Adenine; Adenosine; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemistry; Chemoreceptor Cells; Chemotaxis, Leukocyte; Homocysteine; Humans; Kinetics; Lipid Metabolism; Methylation; Monocytes | 1981 |
Interference of transmethylation inhibitors with thromboxane synthesis in rat platelets.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Homocysteine; Isomerism; Kinetics; Male; Methyltransferases; Rats; Rats, Inbred Strains; Ribonucleosides; Thromboxane B2; Thromboxanes; Tubercidin | 1982 |
Hippocampal electrical activity and gamma-aminobutyrate metabolism in brain tissue following administration of homocysteine.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain; Electrophysiology; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Homocysteine; Male; Rats; Seizures | 1983 |
S-Adenosylhomocysteine accumulation and selective cytotoxicity in cultured T- and B-lymphocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosylhomocysteinase; B-Lymphocytes; Cell Division; Cells, Cultured; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Nucleoside Deaminases; S-Adenosylhomocysteine; T-Lymphocytes | 1982 |
Homocysteine thiolactone and experimental homocysteinemia.
Topics: Animals; Carboxylic Ester Hydrolases; Esterases; Homocysteine; Humans; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Male; Serum Albumin, Bovine; Swine | 1982 |
Experimental homocysteinemia in pigs: comparison with studies in sixteen homocystinuric patients.
Topics: Adolescent; Adult; Amino Acids; Aminobutyrates; Animals; Child; Child, Preschool; Dipeptides; Disease Models, Animal; Homocysteine; Homocystine; Homocystinuria; Humans; Kinetics; Methionine; Middle Aged; Swine; Taurine | 1982 |
The preparation of [35S]homocysteine thiolactone free of [35S]methionine.
Topics: Homocysteine; Isotope Labeling; Methionine; Sulfur Radioisotopes | 1982 |
Inhibition of the hamster sperm acrosome reaction by transmethylation inhibitors.
Topics: Acrosome; Animals; Cricetinae; Homocysteine; In Vitro Techniques; Male; Mesocricetus; Methylation; Ribonucleosides; Sperm Capacitation; Sperm Motility; Spermatozoa; Tubercidin | 1981 |
Decreased transmethylation of biogenic amines after in vivo elevation of brain S-adenosyl-l-homocysteine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Biogenic Amines; Brain; Catechol O-Methyltransferase Inhibitors; Histamine; Histamine N-Methyltransferase; Homocysteine; Hydrolases; Liver; Male; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
The action of three anticlastogens on the induction of sister chromatid exchange by trenimon and 8-hydroxyquinoline sulfate in human lymphocyte cultures.
Topics: Alkylating Agents; beta-Aminoethyl Isothiourea; Cells, Cultured; Crossing Over, Genetic; Cysteine; DNA Repair; Homocysteine; Humans; Hydroxyquinolines; Lymphocytes; Sister Chromatid Exchange | 1980 |
Characterization of adenosine-induced cytostasis in melanoma cells.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Count; Cell Division; Cell Line; Guanosine; Homocysteine; Melanoma; Methylation; Mice; Neoplasms, Experimental; Pyrimidines; RNA, Neoplasm; Uridine | 1980 |
Enhancement of depolarization-dependent release of norepinephrine by an inhibitor of S-adenosylmethionine-dependent transmethylations.
Topics: Adrenal Gland Neoplasms; Animals; Carbachol; Cell Line; Clone Cells; Homocysteine; Kinetics; Norepinephrine; Pheochromocytoma; Potassium; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1980 |
Toxicity, biodistribution and radioprotective capacity of L-homocysteine thiolactone in CNS tissues and tumors in rodents: comparison with prior results with phosphorothioates.
Topics: Amifostine; Animals; Brain; Brain Neoplasms; Female; Homocysteine; Male; Mice; Mice, Inbred C3H; Radiation-Protective Agents; Rats; Rats, Inbred F344; Spinal Cord; Tissue Distribution; Tumor Cells, Cultured | 1995 |
Proofreading in vivo. Editing of homocysteine by aminoacyl-tRNA synthetases in Escherichia coli.
Topics: Amino Acid Sequence; Amino Acids; Amino Acyl-tRNA Synthetases; Escherichia coli; Homocysteine; Molecular Sequence Data; Plasmids; RNA Editing | 1995 |
Oral administration of homocysteine leads to increased plasma triglycerides and homocysteic acid-additional mechanisms in homocysteine induced endothelial damage?
Topics: Administration, Oral; Animals; Endothelium, Vascular; Female; Gas Chromatography-Mass Spectrometry; Homocysteine; Rats; Triglycerides | 1995 |
Steady-state catecholamine stimulation does not increase cytosolic adenosine in canine hearts.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Pressure; Cardiac Pacing, Artificial; Catecholamines; Coronary Circulation; Cytosol; Dogs; Heart; Heart Rate; Hemodynamics; Homocysteine; Homocystine; Myocardial Ischemia; Myocardium; Oxygen Consumption; Reference Values; S-Adenosylhomocysteine | 1994 |
Editing function of Escherichia coli cysteinyl-tRNA synthetase: cyclization of cysteine to cysteine thiolactone.
Topics: Amino Acyl-tRNA Synthetases; Chromatography, Thin Layer; Cysteine; Escherichia coli; Homocysteine; Pyrophosphatases; RNA Editing | 1994 |
The bis(adenosin-N6-yl) alkanes, a family of potential dinucleoside polyphosphate analogue precursors. Mechanism of growth inhibition and suppression of adenosine toxicity in lymphoid cells.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cell Division; Cell Line; Deoxyadenosines; Drug Interactions; Homocysteine; Hydrolases; Lymphocytes; Rats; Tumor Cells, Cultured; Uridine | 1993 |
Intracellular formation and release of adenosine from rat hippocampal slices evoked by electrical stimulation or energy depletion.
Topics: Adenosine; Adenosine Diphosphate; Animals; Electric Stimulation; Energy Metabolism; Hippocampus; Homocysteine; In Vitro Techniques; Intracellular Membranes; Male; Purines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine | 1993 |
Energy cost of proofreading in vivo: the charging of methionine tRNAs in Escherichia coli.
Topics: Energy Metabolism; Escherichia coli; Homocysteine; Methionine; Methionine-tRNA Ligase; Protein Biosynthesis; RNA Editing; RNA, Transfer, Met; Substrate Specificity | 1993 |
Synthesis of homocysteine thiolactone by methionyl-tRNA synthetase in cultured mammalian cells.
Topics: 3T3 Cells; Animals; Cell Line; CHO Cells; Cricetinae; HeLa Cells; Homocysteine; Humans; Methionine; Methionine-tRNA Ligase; Mice; Mutation; Sulfur Radioisotopes; Temperature; Tumor Cells, Cultured | 1993 |
Attenuation of ischemia-induced extracellular adenosine accumulation by homocysteine.
Topics: Adenosine; Analysis of Variance; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Extracellular Space; Homocysteine; Hypoxanthine; Hypoxanthines; Inosine; Male; Rats; Rats, Wistar; S-Adenosylhomocysteine | 1993 |
Apoptosis and transmethylation metabolites in HL-60 cells.
Topics: Adenosine; Apoptosis; DNA; DNA Fragmentation; Enzyme Inhibitors; HL-60 Cells; Homocysteine; Humans; Methylation; Methyltransferases; Nucleic Acid Synthesis Inhibitors; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1996 |
Simultaneous myogenin expression and overall DNA hypomethylation promote in vitro myoblast differentiation.
Topics: Animals; Blotting, Northern; Blotting, Southern; Cell Differentiation; Cells, Cultured; DNA; DNA Methylation; Homocysteine; Muscle Fibers, Skeletal; Muscle, Skeletal; Myogenin; Polymerase Chain Reaction; Rats; RNA, Messenger; Stem Cells; Tubercidin | 1996 |
Homocysteine induces congenital defects of the heart and neural tube: effect of folic acid.
Topics: Animals; Chick Embryo; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; Folic Acid; Gastrula; Heart Defects, Congenital; Homocysteine; Mice; Neural Tube Defects; Teratogens | 1996 |
Metabolism of homocysteine thiolactone in human cell cultures. Possible mechanism for pathological consequences of elevated homocysteine levels.
Topics: Amino Acids; Cells, Cultured; Culture Techniques; Homocysteine; Humans; Proteins | 1997 |
Cyanocobalamin [c-lactam] inhibits vitamin B12 and causes cytotoxicity in HL60 cells: methionine protects cells completely.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Death; Enzyme Inhibitors; Folic Acid; HL-60 Cells; Homocysteine; Humans; Hydroxocobalamin; Methionine; Methylmalonyl-CoA Mutase; Propionates; Tetrahydrofolates; Vitamin B 12 | 1997 |
Determinants of the S-adenosylhomocysteine (SAH) technique for the local assessment of cardiac free cytosolic adenosine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cytosol; Dogs; Heart; Homocysteine; Hydrolases; Myocardium; S-Adenosylhomocysteine | 1997 |
A novel pathway for the conversion of homocysteine to methionine in eukaryotes.
Topics: Animals; Homocysteine; Hydrogen-Ion Concentration; Hydrolysis; Liver; Methionine; Methionine-tRNA Ligase; Multienzyme Complexes; Rabbits; RNA, Transfer, Met; Sheep | 1997 |
Irreversible inhibition of lysyl oxidase by homocysteine thiolactone and its selenium and oxygen analogues. Implications for homocystinuria.
Topics: Animals; Cattle; Enzyme Inhibitors; Homocysteine; Homocystinuria; Isotope Labeling; Kinetics; Oxygen; Protein-Lysine 6-Oxidase; Selenium; Spectrum Analysis; Sulfhydryl Compounds; Sulfur Radioisotopes; Swine | 1997 |
Generation and initial characterization of a novel polyclonal antibody directed against homocysteine thiolactone-modified low density lipoprotein.
Topics: Antibody Specificity; Apolipoprotein B-100; Apolipoproteins B; Binding, Competitive; Cystamine; Enzyme-Linked Immunosorbent Assay; Homocysteine; Lipoproteins, LDL; Lysine; Vascular Diseases | 1998 |
Growth promotion by homocysteine but not by homocysteic acid: a role for excessive growth in homocystinuria or proliferation in hyperhomocysteinemia?
Topics: Adolescent; Adult; Aged; CDC2 Protein Kinase; Cell Division; Cystathionine beta-Synthase; Female; Homocysteine; Homocystinuria; Humans; Male; Middle Aged | 1998 |
Reactivity of homocysteine-thiolactone and alpha-methylhomocysteine-thiolactone with e-(aq) and OH-radical: a pulse radiolysis study.
Topics: Ammonia; Chromatography, Thin Layer; Electrons; Free Radical Scavengers; Homocysteine; Hydrogen Sulfide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxyl Radical; Kinetics; Protons; Pulse Radiolysis; Radiation-Protective Agents; Radiation, Ionizing | 1998 |
Characterization of the adduct formed from the reaction between homocysteine thiolactone and low-density lipoprotein: antioxidant implications.
Topics: Antioxidants; Electron Spin Resonance Spectroscopy; Homocysteine; Humans; Kinetics; Lipoproteins, LDL; Mesylates; Oxidation-Reduction; Protein Binding; Radiation-Protective Agents; Spin Labels; Thiosulfate Sulfurtransferase | 1999 |
Protein homocysteinylation: possible mechanism underlying pathological consequences of elevated homocysteine levels.
Topics: Blood Proteins; Escherichia coli; Homocysteine; Humans; In Vitro Techniques; Kinetics; Protein Denaturation; Sulfur Radioisotopes | 1999 |
Calcium-dependent human serum homocysteine thiolactone hydrolase. A protective mechanism against protein N-homocysteinylation.
Topics: Amino Acids; Arteriosclerosis; Aryldialkylphosphatase; Calcium; Enzyme Inhibitors; Esterases; Homocysteine; Humans; Kinetics; Lipoproteins, HDL; Penicillamine; Sequence Analysis; Substrate Specificity | 2000 |
The possible role of protein-carboxyl methylation in the regulation of flagellar movement of fowl spermatozoa.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium Chloride; Chickens; Enzyme Inhibitors; Homocysteine; Luminescent Measurements; Male; Marine Toxins; Methylation; Oxazoles; Proteins; Semen; Sperm Motility; Sperm Tail; Tubercidin | 2000 |
Homocysteine thiolactone is a positive effector of sigma(S) levels in Escherichia coli.
Topics: Bacterial Proteins; Culture Media; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Homocysteine; Methionine; Repressor Proteins; Sigma Factor; Vitamin B 12 | 2000 |
Homocysteine thiolactone and protein homocysteinylation in human endothelial cells: implications for atherosclerosis.
Topics: Arteriosclerosis; Cells, Cultured; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Infant, Newborn; Lipoproteins, HDL; Methionine; Proteins | 2000 |
Comparative methodologic study of NFkappaB activation in cultured endothelial cells.
Topics: Cells, Cultured; Endothelium, Vascular; Homocysteine; Humans; Interleukin-1; Microscopy, Fluorescence; NF-kappa B | 2000 |
Genetic determinants of homocysteine thiolactonase activity in humans: implications for atherosclerosis.
Topics: Adolescent; Adult; Alleles; Arteriosclerosis; Aryldialkylphosphatase; Black People; DNA; Esterases; Female; Homocysteine; Humans; Male; Polymorphism, Genetic; White People | 2001 |
Homocysteine-thiolactone induces caspase-independent vascular endothelial cell death with apoptotic features.
Topics: Apoptosis; Carbocyanines; Caspases; Cell Death; Cell Line; Cell Membrane; Culture Media; Dose-Response Relationship, Drug; Endothelium, Vascular; Fluorescent Dyes; Homocysteine; Humans; Membrane Potentials; Mitochondria; Peptide Hydrolases; Phosphatidylserines; Proteins | 2000 |
Homocysteine thiolactone induces apoptotic DNA damage mediated by increased intracellular hydrogen peroxide and caspase 3 activation in HL-60 cells.
Topics: Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Survival; DNA; DNA Damage; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Enzyme Activation; Flow Cytometry; HL-60 Cells; Homocysteine; Humans; Hydrogen Peroxide; Mutagenicity Tests; Mutagens; Reactive Oxygen Species | 2001 |
Homocysteine thiolactone inhibits insulin signaling, and glutathione has a protective effect.
Topics: Animals; Glutathione; Homocysteine; Insulin; Insulin Receptor Substrate Proteins; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Rats; Receptor, Insulin; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 2001 |
Methylation is involved in the Ustilago maydis mating response.
Topics: Cyclic AMP; Ethionine; Homocysteine; Methionine; Methylation; Methyltransferases; Mutation; Pheromones; Plants; Reproduction; S-Adenosylmethionine; Signal Transduction; Ustilago | 2001 |
Relative roles of albumin and ceruloplasmin in the formation of homocystine, homocysteine-cysteine-mixed disulfide, and cystine in circulation.
Topics: Ceruloplasmin; Chromatography, High Pressure Liquid; Copper; Cysteine; Disulfides; Dose-Response Relationship, Drug; Homocysteine; Homocystine; Humans; Models, Biological; Oxygen; Protein Binding; Serum Albumin; Sulfhydryl Compounds; Time Factors | 2001 |
Determination of homocysteine thiolactone and homocysteine in cell cultures using high-performance liquid chromatography with fluorescence detection.
Topics: Cell Culture Techniques; Chromatography, High Pressure Liquid; Culture Media; Homocysteine; Reference Standards; Reproducibility of Results; Spectrometry, Fluorescence | 2002 |
Homocysteine thiolactone and protein homocysteinylation: mechanistic studies with model peptides and proteins.
Topics: Homocysteine; Lysine; Mass Spectrometry; Peptides; Protein Binding | 2002 |
Protein-bound homocystamide measured in human plasma by HPLC.
Topics: Adult; Blood Proteins; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Male; Middle Aged; Plasma; Protein Binding; Renal Dialysis | 2002 |
N-Acetylcysteine, vitamin C and vitamin E diminish homocysteine thiolactone-induced apoptosis in human promyeloid HL-60 cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Folic Acid; HL-60 Cells; Homocysteine; Humans; Hydrogen Peroxide; Leukemia, Myeloid; Vitamin E | 2002 |
The determination of homocysteine-thiolactone in biological samples.
Topics: Calibration; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelium, Vascular; Escherichia coli; Extracellular Space; Homocysteine; Humans; Mycobacterium smegmatis; Sensitivity and Specificity | 2002 |
Quantitative assay of plasma homocysteine thiolactone by gas chromatography/mass spectrometry.
Topics: Biomarkers; Deuterium; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Molecular Structure; Reference Standards; Sensitivity and Specificity; Silicon Dioxide | 2003 |
Effect of homocysteinylation on human high-density lipoproteins: a correlation with paraoxonase activity.
Topics: Adult; Aryldialkylphosphatase; Esterases; Homocysteine; Humans; Lipoproteins, HDL; Male; Sulfhydryl Compounds | 2003 |
[Homocysteine-thiolactone, cysteine and fructose therapy of acute and chronic hepatitis].
Topics: Cysteine; Fructose; Hepatitis; Hepatitis A; Hepatitis, Chronic; Homocysteine; Humans; Propionates | 1957 |
Chemical derivatives of alpha-chymotrypsinogen. III. Reaction with N-acetyl-Dl-homocysteine thiolactone.
Topics: Chymotrypsin; Chymotrypsinogen; Homocysteine | 1960 |
[On the opening of the ring and oxidation of the sulfhydryl groups in homocysteine thiolactone].
Topics: Cysteine; Homocysteine; Oxidation-Reduction; Sulfhydryl Compounds | 1960 |
[The influence of 1-cysteine, d, 1-homocysteine thiolactone and d-fructose on the 17-ketosteroid fractions in the urine of patients with liver diseases].
Topics: 17-Ketosteroids; Body Fluids; Cysteine; Fructose; Homocysteine; Humans; Liver Diseases; Organic Chemicals | 1959 |
[On the protective effect of beta-aminoethyliso-thiuronium (AET) and alpha-homocysteine thiolactone (HCT) against nitrogen-lost in the mouse].
Topics: Animals; Cysteine; Homocysteine; Mechlorethamine; Mice; Nitrogen; Nitrogen Mustard Compounds; Sulfhydryl Compounds | 1960 |
L-CYSTINE REQUIREMENT FOR PRODUCTION OF COXSACKIE B3 VIRUS IN CULTURED MONKEY HEART CELLS.
Topics: Amino Acids; Animals; Cystine; Enterovirus; Ethionine; Glycine; Haplorhini; Heart; Homocysteine; Homocystine; Mercaptoethylamines; Research; Sulfhydryl Compounds; Tissue Culture Techniques; Virus Cultivation | 1963 |
[THERAPY OF ACUTE AND CHRONIC HEPATIC DISEASES WITH THE DRUG ASSOCIATION, HOMOCYSTEINE-THIOLACTONE, CYSTEINE AND FRUCTOSE].
Topics: Chemical and Drug Induced Liver Injury; Cysteine; Fructose; Hepatitis; Hepatitis A; Hepatitis B virus; Homocysteine; Humans; Lactones; Liver Cirrhosis; Liver Diseases | 1963 |
[THE LIVER PROTECTIVE EFFECT OF CYSTEINE, HOMOCYSTEINE THIOLACTONE AND N-ACETYLHOMOCYSTEINE THIOLACTONE IN EXPERIMENTAL LIVER DAMAGE].
Topics: Alcohols; Aspartate Aminotransferases; Benzene; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cysteine; Hepatitis; Homocysteine; Lactones; Liver Function Tests; Rats; Research; Sulfobromophthalein; Thiophenes; Toxicology | 1963 |
THE REACTION OF INSULIN WITH N-ACETYL-DL-HOMOCYSTEINE THIOLACTONE: SOME CHEMICAL AND BIOLOGICAL PROPERTIES OF THE PRODUCTS.
Topics: Animals; Blood Glucose; Chemical Phenomena; Chemistry; Chromatography; Homocysteine; Insulin; Iodoacetates; Lactones; Methionine; Pharmacology; Rabbits; Research; Sulfhydryl Compounds | 1964 |
An in vitro evaluation of the effects of homocysteine thiolactone on key steps of angiogenesis and tumor invasion.
Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Animals; Aorta; Cattle; Cell Differentiation; Cell Division; Cell Line, Tumor; Cell Movement; Collagen; Culture Media, Conditioned; Dose-Response Relationship, Drug; Drug Combinations; Endothelium, Vascular; Homocysteine; Humans; In Vitro Techniques; Laminin; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Proteoglycans; Time Factors | 2003 |
Prevention of homocysteine thiolactone induced atherogenesis in rats.
Topics: Animals; Aorta, Thoracic; Arterial Occlusive Diseases; Arteries; Arteriosclerosis; Cobamides; Female; Food; Homocysteine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Propylene Glycol; Rats; Tissue Fixation; Tretinoin; Vitamin B 12; Weight Gain | 2002 |
Homocysteine thiolactone induces apoptosis in cultured human trophoblasts: a mechanism for homocysteine-mediated placental dysfunction?
Topics: Apoptosis; Blotting, Western; Cells, Cultured; Female; Homocysteine; Humans; Placenta; Placenta Diseases; Pregnancy; Time Factors; Trophoblasts | 2004 |
Modification induced by homocysteine and low-density lipoprotein on human aortic endothelial cells: an in vitro study.
Topics: Adult; Aorta; Calcium; Cells, Cultured; Endothelial Cells; Homocysteine; Humans; Lipoproteins, LDL; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Sodium-Potassium-Exchanging ATPase | 2004 |
Urinary excretion of homocysteine-thiolactone in humans.
Topics: Adult; Chromatography, High Pressure Liquid; Fluorescence; Homocysteine; Humans; Middle Aged; Plasma | 2005 |
The determination of homocysteine-thiolactone in human plasma.
Topics: Calibration; Chromatography, High Pressure Liquid; Health; Homocysteine; Humans; Molecular Structure; Sensitivity and Specificity | 2005 |
Homocysteine thiolactone inhibits insulin-stimulated DNA and protein synthesis: possible role of mitogen-activated protein kinase (MAPK), glycogen synthase kinase-3 (GSK-3) and p70 S6K phosphorylation.
Topics: Animals; Cell Proliferation; DNA Replication; Glycogen Synthase Kinase 3; Homocysteine; Insulin; Mitogen-Activated Protein Kinases; Protein Biosynthesis; Rats; Ribosomal Protein S6 Kinases, 70-kDa | 2005 |
Plasma homocysteine thiolactone adducts associated with risk of coronary heart disease.
Topics: Adult; Alleles; Aryldialkylphosphatase; Coronary Disease; Enzyme-Linked Immunosorbent Assay; Female; Gene Frequency; Genotype; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors | 2006 |
Mechanism of hydrolysis and aminolysis of homocysteine thiolactone.
Topics: 4-Butyrolactone; Atherosclerosis; Homocysteine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Predictive Value of Tests | 2006 |
Modification of fibrinogen by homocysteine thiolactone increases resistance to fibrinolysis: a potential mechanism of the thrombotic tendency in hyperhomocysteinemia.
Topics: Amino Acid Sequence; Blood Coagulation; Dose-Response Relationship, Drug; Fibrin; Fibrinogen; Fibrinolysis; Homocysteine; Humans; Hyperhomocysteinemia; Lysine; Models, Biological; Molecular Sequence Data; Plasminogen; Protein Binding; Radiation-Protective Agents; Structure-Activity Relationship; Thrombosis; Tissue Plasminogen Activator | 2006 |
Homocysteine and other structurally-diverse amino thiols can alter pancreatic beta cell function without evoking cellular damage.
Topics: Animals; Cell Lineage; Cell Survival; Cysteic Acid; Glucose; Homocysteine; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Models, Chemical; Rats; Sulfhydryl Compounds; Sulfinic Acids | 2006 |
Pathophysiological consequences of homocysteine excess.
Topics: Autoantibodies; Blood Proteins; Cell Death; Diet; Endoplasmic Reticulum; Homocysteine; Humans; Hyperhomocysteinemia; Lysine; Methionine; Protein Binding | 2006 |
Comparative study on in vitro effects of homocysteine thiolactone and homocysteine on HUVEC cells: evidence for a stronger proapoptotic and proinflammative homocysteine thiolactone.
Topics: Antioxidants; Apoptosis; Caspase 3; Cell Survival; Cells, Cultured; DNA Fragmentation; Endothelial Cells; Homocysteine; Humans; Inflammation Mediators; Interleukin-8; L-Lactate Dehydrogenase; Umbilical Veins | 2006 |
Antioxidant activity of vitamin B6 delays homocysteine-induced atherosclerosis in rats.
Topics: Animals; Aorta; Atherosclerosis; Blood Glucose; Cholesterol; Homocysteine; Lipids; Male; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Wistar; Time Factors; Triglycerides; Vitamin B 6; Vitamin B 6 Deficiency; Vitamins | 2006 |
Homocysteinylation of low-density lipoproteins (LDL) from subjects with Type 1 diabetes: effect on oxidative damage of human endothelial cells.
Topics: Adult; Aorta; Atherosclerosis; Diabetes Mellitus, Type 1; Endothelial Cells; Homocysteine; Humans; Lipoproteins, LDL; Male; Peroxynitrous Acid; Radiation-Protective Agents | 2006 |
Modulation by homocysteine of the iberiotoxin-sensitive, Ca2+ -activated K+ channels of porcine coronary artery smooth muscle cells.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetophenones; Angiotensin II; Animals; Benzimidazoles; Calcium; Coronary Vessels; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Homocysteine; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Muscle, Smooth, Vascular; NAD; NADPH Oxidases; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Superoxides; Swine; Vasoconstrictor Agents | 2006 |
Mechanism of the condensation of homocysteine thiolactone with aldehydes.
Topics: Aldehydes; Homocysteine; Pyridines; Pyridoxal Phosphate; Thiazines | 2006 |
Homocysteine thiolactone and human cholinesterases.
Topics: Acetylcholinesterase; Butyrylcholinesterase; Enzyme Activation; Homocysteine; Humans; Models, Biological; Structure-Activity Relationship | 2007 |
Synthesis of N-acyl homoserine lactone analogues reveals strong activators of SdiA, the Salmonella enterica serovar Typhimurium LuxR homologue.
Topics: 4-Butyrolactone; Bacterial Proteins; Cyclohexanols; Gene Expression Regulation, Bacterial; Homocysteine; Humans; Quorum Sensing; Repressor Proteins; Salmonella typhimurium; Trans-Activators | 2007 |
Homocysteine thiolactone-induced hyperhomocysteinemia does not alter concentrations of cholesterol and SREBP-2 target gene mRNAS in rats.
Topics: Animals; Cholesterol; Diet; Disease Models, Animal; Gene Expression; Homocysteine; Hydroxymethylglutaryl CoA Reductases; Hyperhomocysteinemia; Intestine, Small; Lipoproteins; Liver; Rats; Rats, Sprague-Dawley; Receptors, LDL; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sterol Regulatory Element Binding Protein 2 | 2007 |
[Association of paraoxonase polymorphisms and serum homocysteine thiolactone complex with coronary heart disease].
Topics: Adult; Aged; Aryldialkylphosphatase; Coronary Disease; Cysteine; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Male; Middle Aged; Polymorphism, Genetic | 2006 |
Mutations in methylenetetrahydrofolate reductase or cystathionine beta-synthase gene, or a high-methionine diet, increase homocysteine thiolactone levels in humans and mice.
Topics: Animals; Cystathionine beta-Synthase; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mutation | 2007 |
Major metabolic homocysteine-derivative, homocysteine thiolactone, exerts changes in pancreatic beta-cell glucose-sensing, cellular signal transduction and integrity.
Topics: Animals; Cell Line; Glucose; Homocysteine; Insulin; Insulin Secretion; Insulin-Secreting Cells; Rats; Signal Transduction | 2007 |
Modification by homocysteine thiolactone affects redox status of cytochrome C.
Topics: Animals; Binding Sites; Circular Dichroism; Cytochromes c; Homocysteine; Horses; Hyperhomocysteinemia; Lysine; Oxidation-Reduction; Protein Processing, Post-Translational; Protein Structure, Secondary | 2007 |
Facile syntheses of [35S]homocysteine-thiolactone, [35S]homocystine, [35S]homocysteine, and [S-nitroso-35S]homocysteine.
Topics: Homocysteine; Homocystine; Isotope Labeling; Nitroso Compounds; Sulfur Isotopes | 2007 |
Impairment of endothelium-dependent relaxation of rat aortas by homocysteine thiolactone and attenuation by captopril.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Captopril; Dose-Response Relationship, Drug; Enalaprilat; Endothelium, Vascular; Free Radicals; Homocysteine; Losartan; Malondialdehyde; Nitric Oxide; Nitroprusside; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasodilation | 2007 |
Capillary electrophoretic screening for the inhibition of homocysteine thiolactone-induced protein oligomerization.
Topics: Animals; Cations; Cattle; Cytochromes c; Dose-Response Relationship, Drug; Electrophoresis, Capillary; Homocysteine; Polyethylenes; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Reproducibility of Results; Sensitivity and Specificity; Temperature; Time Factors | 2007 |
Mercaptopropionaldehyde from homocysteine: implications for Alzheimer's disease.
Topics: 3-Mercaptopropionic Acid; Aldehydes; Alzheimer Disease; Amyloid beta-Protein Precursor; Chemical Precipitation; Homocysteine; Humans; Neurofibrillary Tangles; Plaque, Amyloid | 2007 |
Antithrombin activity is inhibited by acrolein and homocysteine thiolactone: Protection by cysteine.
Topics: Acrolein; Antithrombins; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Homocysteine; Humans; Plasminogen; Time Factors | 2008 |
Gold nanoparticle sensor for homocysteine thiolactone-induced protein modification.
Topics: Gold; Homocysteine; Humans; Metal Nanoparticles; Microscopy, Electron, Transmission; Serum Albumin; Spectrophotometry; Temperature | 2008 |
New method for the determination of protein N-linked homocysteine.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Ferritins; Homocysteine; Humans; Milk; Proteins; Spectrometry, Fluorescence | 2008 |
Homocysteine levels, paraoxonase 1 (PON1) activity, and cardiovascular risk.
Topics: Aryldialkylphosphatase; Carboxylic Ester Hydrolases; Cardiovascular Diseases; Homocysteine; Humans; Oxidative Stress; Risk Assessment; Risk Factors | 2008 |
Role of fluorosurfactant-modified gold nanoparticles in selective detection of homocysteine thiolactone: remover and sensor.
Topics: Biosensing Techniques; Female; Fluorescent Dyes; Gold; Homocysteine; Humans; Metal Nanoparticles; Sensitivity and Specificity; Surface-Active Agents | 2008 |
Mutations in cystathionine beta-synthase or methylenetetrahydrofolate reductase gene increase N-homocysteinylated protein levels in humans.
Topics: Adolescent; Adult; Aged; Cystathionine beta-Synthase; Fibrinogen; Genes; Homocysteine; Homocystinuria; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation | 2008 |
Plasma homocysteine thiolactone associated with risk of macrovasculopathy in Chinese patients with type 2 diabetes mellitus.
Topics: Age Factors; Asian People; Body Mass Index; China; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Middle Aged; Risk Factors; Smoking; Time Factors; Vitamin B 12 | 2008 |
Two types of seizures in homocysteine thiolactone-treated adult rats, behavioral and electroencephalographic study.
Topics: Animals; Behavior, Animal; Electroencephalography; Homocysteine; Rats; Rats, Wistar; Seizures | 2009 |
Comparative studies on homocysteine and its metabolite-homocysteine thiolactone action in blood platelets in vitro.
Topics: Blood Platelets; Cells, Cultured; Dose-Response Relationship, Drug; Homocysteine; Homocystine; Humans; Nitrates; Platelet Activation; Platelet Aggregation; Protein Processing, Post-Translational; Superoxides; Thrombin; Tyrosine | 2008 |
Modification with homocysteine does not increase susceptibility of human low-density lipoprotein to iron-mediated oxidation.
Topics: Copper; Homocysteine; Humans; Iron; Lipid Peroxidation; Lipoproteins, LDL; Male; Sulfhydryl Compounds | 2008 |
Homocysteine and inflammation as main determinants of oxidative stress in the elderly.
Topics: Aged; Aged, 80 and over; Aging; C-Reactive Protein; Cell Line; Enzyme Activation; Female; Homocysteine; Humans; Inflammation; Lipid Metabolism; Male; Monocytes; NADPH Oxidases; Nutrition Assessment; Oxidative Stress; Prealbumin; Superoxides | 2009 |
Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice.
Topics: Animals; Cystathionine beta-Synthase; Diet; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver; Membrane Transport Proteins; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Mice, Knockout | 2009 |
The activity of erythrocyte and brain Na+/K+ and Mg2+-ATPases in rats subjected to acute homocysteine and homocysteine thiolactone administration.
Topics: Animals; Brain; Ca(2+) Mg(2+)-ATPase; Erythrocytes; Homocysteine; Male; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase | 2009 |
Homocysteine editing and growth inhibition in Escherichia coli.
Topics: Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Energy Metabolism; Escherichia coli; Homocysteine; Isoleucine; Leucine; Methionine; Protein Biosynthesis; Sodium Acetate | 2009 |
Modification of human blood platelet proteins induced by homocysteine and its thiolactone in vitro.
Topics: Adult; Blood Platelets; Blood Proteins; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Esters; Homocysteine; Humans; Platelet Aggregation; Platelet-Rich Plasma; Signal Transduction; Sulfhydryl Compounds; Thrombin; Tyrosine | 2009 |
Hyperhomocysteinemia induced by feeding rats diets rich in DL-homocysteine thiolactone promotes alterations on carotid reactivity independent of arterial structure.
Topics: Animals; Carotid Arteries; Feeding Methods; Homocysteine; Hyperhomocysteinemia; Male; Rats; Rats, Wistar; Vasoconstriction; Vasodilation | 2009 |
Defective responses to oxidative stress in protein l-isoaspartyl repair-deficient Caenorhabditis elegans.
Topics: Animals; Antioxidants; Ascorbic Acid; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Cycle Proteins; Genotype; Homocysteine; Larva; Metamorphosis, Biological; Methyltransferases; Mutation; Naphthoquinones; Oxidants; Oxidative Stress; Paraquat; Phenotype; Receptor, Insulin | 2009 |
The role of nitric oxide in homocysteine thiolactone-induced seizures in adult rats.
Topics: Animals; Anticonvulsants; Behavior, Animal; Electroencephalography; Enzyme Inhibitors; Homocysteine; Humans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Radiation-Protective Agents; Rats; Rats, Wistar; Seizures; Sodium-Potassium-Exchanging ATPase | 2010 |
Paraoxonase 1 protects against protein N-homocysteinylation in humans.
Topics: Adolescent; Adult; Aged; Aryldialkylphosphatase; Cystathionine beta-Synthase; Homocysteine; Homocystinuria; Humans; Middle Aged; Young Adult | 2010 |
Modulation of paraoxonase 1 and protein N-homocysteinylation by leptin and the synthetic liver X receptor agonist T0901317 in the rat.
Topics: Acetophenones; Animals; Aryldialkylphosphatase; Blood Proteins; Homocysteine; Hydrocarbons, Fluorinated; Leptin; Liver; Liver X Receptors; Male; NADPH Oxidases; Orphan Nuclear Receptors; Oxidative Stress; Rats; Rats, Wistar; Sulfonamides | 2010 |
High dose of ethanol decreases total spectral power density in seizures induced by D,L-homocysteine thiolactone in adult rats.
Topics: Animals; Dose-Response Relationship, Drug; Electroencephalography; Ethanol; Homocysteine; Male; Rats; Rats, Wistar; Seizures; Time Factors | 2009 |
Kinetics of albumin homocysteinylation measured with matrix-assisted laser/desorption ionization mass spectrometry versus with a radioactive tracer.
Topics: Dithiothreitol; Homocysteine; Humans; Isotope Labeling; Kinetics; Radioisotopes; Sensitivity and Specificity; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfur Isotopes; Time Factors | 2009 |
Homocysteine thiolactone induces cardiac dysfunction: role of oxidative stress.
Topics: Animals; Cardiovascular Diseases; Homocysteine; Male; Oxidative Stress; Rats; Rats, Wistar | 2010 |
Electrochemical probing into cytochrome c modification with homocysteine-thiolactone.
Topics: Animals; Cytochromes c; Electrochemistry; Homocysteine; Horses; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet | 2010 |
Homocysteinethiolactone and paraoxonase: novel markers of diabetic retinopathy.
Topics: Aged; Aryldialkylphosphatase; Cells, Cultured; Chromatography, High Pressure Liquid; Diabetic Retinopathy; Female; Homocysteine; Humans; Male; Middle Aged; Retinal Perforations; Tandem Mass Spectrometry; Vitreous Body | 2010 |
May modifications of human plasma proteins stimulated by homocysteine and its thiolactone induce changes of hemostatic function of plasma in vitro?
Topics: Acylation; Adult; Blood Coagulation; Blood Proteins; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia; In Vitro Techniques; Sulfhydryl Compounds | 2010 |
Identification of N-homocysteinylated apolipoprotein AI in normal human serum.
Topics: Apolipoprotein A-I; Atherosclerosis; Biomarkers; Blood Chemical Analysis; Homocysteine; Humans; Lipoproteins, HDL | 2010 |
Purification and kinetic properties of rabbit liver paraoxonase 1.
Topics: Animals; Aryldialkylphosphatase; Blotting, Western; Chromatography, Liquid; Electrophoresis, Polyacrylamide Gel; Homocysteine; Kinetics; Liver; Microsomes, Liver; Rabbits | 2010 |
Modulation of homocysteine toxicity by S-nitrosothiol formation: a mechanistic approach.
Topics: Copper; Electron Spin Resonance Spectroscopy; Homocysteine; Kinetics; Nitrites; S-Nitrosothiols; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfhydryl Compounds | 2010 |
Homocysteine and its thiolactone may promote apoptotic events in blood platelets in vitro.
Topics: Adult; Apoptosis; Blood Platelets; Female; Homocysteine; Humans; Male; Platelet Activation | 2010 |
Determination of homocysteine thiolactone, reduced homocysteine, homocystine, homocysteine-cysteine mixed disulfide, cysteine and cystine in a reaction mixture by overimposed pressure/voltage capillary electrophoresis.
Topics: Calibration; Electrophoresis, Capillary; Homocysteine; Homocystine; Pressure | 2010 |
Differential hydrolysis of homocysteine thiolactone by purified human serum (192)Q and (192)R PON1 isoenzymes.
Topics: Ammonium Sulfate; Aryldialkylphosphatase; Atherosclerosis; Blotting, Western; Chemical Precipitation; Chromatography, Liquid; Homocysteine; Humans; Isoenzymes; Kinetics; Paraoxon; Phenylacetates | 2011 |
Integrin α(IIb)β₃ exists in an activated state in subjects with elevated plasma homocysteine levels.
Topics: Antibodies; Binding Sites, Antibody; Blood Platelets; Case-Control Studies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Integrins; Male; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Risk Factors; Sulfhydryl Compounds; Thrombosis | 2011 |
Comparison of the effect of homocysteine in the reduced form, its thiolactone and protein homocysteinylation on hemostatic properties of plasma.
Topics: Adult; Blood Coagulation; Blood Proteins; Fibrinogen; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia; Lysine; Oxidation-Reduction; Sulfhydryl Compounds | 2011 |
The polyphenol-rich extract from grape seeds suppresses toxicity of homocysteine and its thiolactone on the fibrinolytic system.
Topics: Drug Interactions; Fibrinolysis; Flavonoids; Homocysteine; Humans; Phenols; Plant Extracts; Polyphenols; Seeds; Vitis | 2011 |
Analysis of site-specific N-homocysteinylation of human serum albumin in vitro and in vivo using MALDI-ToF and LC-MS/MS mass spectrometry.
Topics: Amino Acid Sequence; Chromatography, Liquid; Homocysteine; Humans; Lysine; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2011 |
The effect of N-methyl-D-aspartate receptor antagonists on D,L-homocysteine thiolactone induced seizures in adult rats.
Topics: Animals; Dizocilpine Maleate; Homocysteine; Male; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 2011 |
Response of blood platelets to resveratrol during a model of hyperhomocysteinemia.
Topics: Adult; Antioxidants; Blood Platelets; Homocysteine; Humans; Hyperhomocysteinemia; Platelet Aggregation; Resveratrol; Stilbenes; Superoxides; Young Adult | 2011 |
Effect of homocysteine thiolactone on structure and aggregation propensity of bovine pancreatic insulin.
Topics: Animals; Cattle; Circular Dichroism; Homocysteine; Insulin; Kinetics; Light; Pancreas; Protein Conformation; Protein Stability; Scattering, Radiation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2011 |
Anticonvulsive effect of folic acid in homocysteine thiolactone-induced seizures.
Topics: Animals; Anticonvulsants; Behavior, Animal; Electroencephalography; Folic Acid; Homocysteine; Male; Rats; Rats, Wistar; Seizures | 2011 |
Intravitreal homocysteine-thiolactone injection leads to the degeneration of multiple retinal cells, including photoreceptors.
Topics: Animals; Calbindins; Diabetic Retinopathy; Dose-Response Relationship, Drug; Eye Proteins; Female; Glial Fibrillary Acidic Protein; Homeodomain Proteins; Homocysteine; Hyperhomocysteinemia; Immunoblotting; Immunohistochemistry; Intravitreal Injections; LIM-Homeodomain Proteins; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Paired Box Transcription Factors; PAX6 Transcription Factor; Photoreceptor Cells; Repressor Proteins; Retina; Retinal Degeneration; Retinal Ganglion Cells; Rhodopsin; S100 Calcium Binding Protein G; Transcription Factors | 2011 |
Homocysteine and its thiolactone-mediated modification of fibrinogen affect blood platelet adhesion.
Topics: Adult; Blood Platelets; Fibrinogen; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia; Platelet Adhesiveness; Young Adult | 2012 |
Homocysteine and its thiolactone impair plasmin activity induced by urokinase or streptokinase in vitro.
Topics: Adult; Animals; Fibrinolysin; Homocysteine; Humans; Hydrolysis; Plasminogen; Proteolysis; Streptokinase; Urokinase-Type Plasminogen Activator; Young Adult | 2012 |
Metabolism and neurotoxicity of homocysteine thiolactone in mice: protective role of bleomycin hydrolase.
Topics: Animals; Blood Proteins; Brain; Cysteine Endopeptidases; Female; Half-Life; Homocysteine; Hyperhomocysteinemia; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurodegenerative Diseases; Organ Specificity; Seizures | 2012 |
Aronia melanocarpa extract suppresses the biotoxicity of homocysteine and its metabolite on the hemostatic activity of fibrinogen and plasma.
Topics: Adult; Anticoagulants; Antioxidants; Blood Coagulation; Cardiovascular Diseases; Coagulants; Dietary Supplements; Fibrinogen; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological; Oxidative Stress; Photinia; Plant Extracts; Poland; Polymerization; Resveratrol; Stilbenes | 2012 |
Metabolism and neurotoxicity of homocysteine thiolactone in mice: evidence for a protective role of paraoxonase 1.
Topics: Alzheimer Disease; Animals; Aryldialkylphosphatase; Brain; Epilepsy; Homocysteine; Hyperhomocysteinemia; Injections, Intraperitoneal; Kidney; Liver; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nerve Degeneration; Spleen | 2012 |
Inhibition of the neuronal nitric oxide synthase potentiates homocysteine thiolactone-induced seizures in adult rats.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Homocysteine; Indazoles; Male; Neurons; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Seizures | 2012 |
The enhancing effect of homocysteine thiolactone on insulin fibrillation and cytotoxicity of insulin fibril.
Topics: Animals; Cattle; Cell Line; Homocysteine; Humans; Hydrophobic and Hydrophilic Interactions; Insulin; Multiprotein Complexes; Protein Structure, Tertiary | 2012 |
Changes of blood platelet adhesion to collagen and fibrinogen induced by homocysteine and its thiolactone.
Topics: Adult; Analysis of Variance; Blood Platelets; Cell Adhesion; Collagen; Fibrinogen; Hemostasis; Homocysteine; Humans; Young Adult | 2012 |
The polyphenol-rich extracts from black chokeberry and grape seeds impair changes in the platelet adhesion and aggregation induced by a model of hyperhomocysteinemia.
Topics: Adult; Antioxidants; Blood Platelets; Cardiovascular Diseases; Collagen; Dietary Supplements; Fibrinogen; Fruit; Grape Seed Extract; Homocysteine; Humans; Hyperhomocysteinemia; Photinia; Plant Extracts; Platelet Activation; Platelet Aggregation Inhibitors; Polyphenols; Seeds; Superoxides; Vitis; Young Adult | 2013 |
The effects of homocysteine-related compounds on cardiac contractility, coronary flow, and oxidative stress markers in isolated rat heart.
Topics: Animals; Biomarkers; Coronary Circulation; Heart; Homocysteine; In Vitro Techniques; Male; Myocardial Contraction; Oxidative Stress; Rats; Rats, Wistar | 2012 |
Phenolic fractions from Trifolium pallidum and Trifolium scabrum aerial parts in human plasma protect against changes induced by hyperhomocysteinemia in vitro.
Topics: Adult; Antioxidants; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Homocysteine; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Oxidative Stress; Phenols; Plant Components, Aerial; Prothrombin Time; Thiobarbituric Acid Reactive Substances; Thrombin Time; Trifolium | 2012 |
Electrosprayed polyelectrolyte complexes between mucoadhesive N,N,N,-trimethylchitosan-homocysteine thiolactone and alginate/carrageenan for camptothecin delivery.
Topics: Alginates; Antineoplastic Agents, Phytogenic; Camptothecin; Carrageenan; Chitosan; Drug Carriers; Drug Delivery Systems; Electrochemical Techniques; Glucuronic Acid; Hexuronic Acids; Homocysteine; Microscopy, Electron, Scanning; Mucins; Polymers; Spectroscopy, Fourier Transform Infrared; Tissue Adhesives | 2012 |
Effect of homocysteinylation on structure, chaperone activity and fibrillation propensity of lens alpha-crystallin.
Topics: alpha-Crystallins; Amyloid; Animals; Cataract; Cattle; Circular Dichroism; Eye; Glycosylation; Homocysteine; Hydrophobic and Hydrophilic Interactions; Lens, Crystalline; Protein Conformation; Protein Structure, Secondary; Spectrometry, Fluorescence | 2013 |
Paradoxical sleep deprivation potentiates epilepsy induced by homocysteine thiolactone in adult rats.
Topics: Animals; Disease Models, Animal; Electroencephalography; Epilepsy; Homocysteine; Male; Rats; Rats, Wistar; Sleep Deprivation; Sleep, REM | 2013 |
Homocysteine thiolactone-induced seizures in adult rats are aggravated by inhibition of inducible nitric oxide synthase.
Topics: Animals; Behavior, Animal; Electroencephalography; Homocysteine; Male; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Seizures | 2014 |
Increased homocysteine, homocysteine-thiolactone, protein homocysteinylation and oxidative stress in the circulation of patients with Eales' disease.
Topics: Adolescent; Adult; Biomarkers; Homocysteine; Humans; Male; Neovascularization, Pathologic; Oxidative Stress; Retinal Vasculitis; Thiobarbituric Acid Reactive Substances; Young Adult | 2013 |
Homocysteine thiolactone affects protein ubiquitination in yeast.
Topics: Fungal Proteins; Homocysteine; Metabolic Engineering; Mutation; Proteasome Endopeptidase Complex; Proteolysis; Saccharomyces cerevisiae; Ubiquitinated Proteins; Ubiquitination | 2013 |
Exercise decreases susceptibility to homocysteine seizures: the role of oxidative stress.
Topics: Animals; Catalase; Disease Models, Animal; Electroencephalography; Hippocampus; Homocysteine; Male; Malondialdehyde; Oxidative Stress; Physical Conditioning, Animal; Rats, Wistar; Seizures; Superoxide Dismutase; Thiobarbiturates | 2014 |
Development and validation of a LC-MS/MS method for homocysteine thiolactone in plasma and evaluation of its stability in plasma samples.
Topics: Adult; Chromatography, High Pressure Liquid; Drug Stability; Female; Homocysteine; Humans; Limit of Detection; Male; Reproducibility of Results; Tandem Mass Spectrometry; Young Adult | 2014 |
Design, synthesis and in vitro evaluation of mucoadhesive p-coumarate-thiolated-chitosan as a hydrophobic drug carriers.
Topics: Adhesives; Animals; Chitosan; Coumaric Acids; Drug Carriers; Drug Design; Drug Evaluation, Preclinical; Homocysteine; Hydrophobic and Hydrophilic Interactions; Mucins; Propionates; Swine | 2014 |
Effects of DL-homocysteine thiolactone on cardiac contractility, coronary flow, and oxidative stress markers in the isolated rat heart: the role of different gasotransmitters.
Topics: Animals; Biomarkers; Coronary Circulation; Gasotransmitters; Heart; Homocysteine; Hydrogen Peroxide; Male; Muscle Contraction; Myocardial Contraction; Myocardium; Oxidative Stress; Rats; Rats, Wistar | 2013 |
Characterization of N-homocysteinylated albumin adducts.
Topics: Homocysteine; Humans; Lysine; Methionine; Serum Albumin | 2014 |
Impact of homocysteine-thiolactone on plasma fibrin networks.
Topics: Animals; Blood Coagulation; Cattle; Fibrin; Homocysteine; Humans; Plasma | 2014 |
Enhanced water-solubility and mucoadhesion of N,N,N-trimethyl-N-gluconate-N-homocysteine thiolactone chitosan.
Topics: Chitosan; Gluconates; Homocysteine; Lactones; Solubility; Water | 2014 |
Determination of homocysteine thiolactone in urine by field amplified sample injection and sweeping MEKC method with UV detection.
Topics: Chromatography, Micellar Electrokinetic Capillary; Homocysteine; Humans; Limit of Detection; Liquid-Liquid Extraction; Reproducibility of Results | 2014 |
Creation of catalytically active particles from enzymes crosslinked with a natural bifunctional agent--homocysteine thiolactone.
Topics: Animals; Calorimetry, Differential Scanning; Catalysis; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Homocysteine; Hydrodynamics; L-Lactate Dehydrogenase; Lysine; Microscopy, Electron, Transmission; Models, Molecular; NAD; Rabbits | 2014 |
Synthesis and characterization of a novel chitosan-N-acetyl-homocysteine thiolactone polymer using MES buffer.
Topics: Alkanesulfonic Acids; Buffers; Chitosan; Green Chemistry Technology; Homocysteine; Morpholines; Viscoelastic Substances; Viscosity | 2014 |
Existence of molten globule state in homocysteine-induced protein covalent modifications.
Topics: Animals; Cattle; Chemical Phenomena; Chickens; Circular Dichroism; Cytochromes c; Homocysteine; Lactalbumin; Muramidase; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins; Spectrometry, Fluorescence | 2014 |
The effects of the modulation of NMDA receptors by homocysteine thiolactone and dizocilpine on cardiodynamics and oxidative stress in isolated rat heart.
Topics: Animals; Biomarkers; Coronary Circulation; Dizocilpine Maleate; Heart; Heart Function Tests; Homocysteine; In Vitro Techniques; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2015 |
N-homocysteinylation induces different structural and functional consequences on acidic and basic proteins.
Topics: Animals; Cattle; Chickens; Circular Dichroism; Homocysteine; Lactalbumin; Muramidase; Protein Denaturation; Ribonuclease, Pancreatic | 2014 |
The role of endoplasmic reticulum stress in endothelial dysfunction induced by homocysteine thiolactone.
Topics: Active Transport, Cell Nucleus; Animals; Aorta; Cells, Cultured; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Endothelium, Vascular; Heat-Shock Proteins; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Inflammation Mediators; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Vasodilation; Vasodilator Agents | 2015 |
Rosiglitazone via PPARγ-dependent suppression of oxidative stress attenuates endothelial dysfunction in rats fed homocysteine thiolactone.
Topics: Animals; Aorta, Thoracic; Blotting, Western; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Male; Microscopy, Fluorescence; NADPH Oxidases; NF-kappa B; Oxidative Stress; PPAR gamma; Rats, Sprague-Dawley; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones; Vasodilation | 2015 |
Hydrogen sulfide decreases the plasma lipid peroxidation induced by homocysteine and its thiolactone.
Topics: Blood Coagulation; Blood Platelets; Fibrinolysis; Homocysteine; Humans; Hydrogen Sulfide; Lipid Peroxidation; Lipids; Superoxides | 2015 |
Homocysteine thiolactone and N-homocysteinylated protein induce pro-atherogenic changes in gene expression in human vascular endothelial cells.
Topics: Atherosclerosis; Cells, Cultured; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Metabolic Networks and Pathways; Transcriptional Activation; Transcriptome | 2015 |
Crosstalk of homocysteinylation, methylation and acetylation on histone H3.
Topics: Acetylation; Amino Acid Sequence; HCT116 Cells; HEK293 Cells; Histones; Homocysteine; Humans; Mass Spectrometry; Metabolic Networks and Pathways; Methylation; Molecular Sequence Data; Protein Processing, Post-Translational | 2015 |
Role of Nox inhibitors plumbagin, ML090 and gp91ds-tat peptide on homocysteine thiolactone induced blood vessel dysfunction.
Topics: Animals; Aorta, Abdominal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycoproteins; Homocysteine; Male; NADPH Oxidases; Naphthoquinones; Quinoxalines; Rabbits | 2015 |
Organotypic tissue culture investigation of homocysteine thiolactone cardiotoxic effect.
Topics: Animals; Cell Proliferation; Chick Embryo; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart; Homocysteine; Myocytes, Cardiac; Ouabain; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Tissue Culture Techniques | 2015 |
Design of protein homocystamides with enhanced tumor uptake properties for (19)F magnetic resonance imaging.
Topics: Animals; Brain; Cell Line, Tumor; Cell Survival; Contrast Media; Drug Design; Female; Fluorine-19 Magnetic Resonance Imaging; Free Radicals; Homocysteine; Humans; Mice; Mice, SCID; Microscopy, Fluorescence; Neoplasms; Radiography; Serum Albumin; Transplantation, Heterologous | 2015 |
The Structural Alteration and Aggregation of Bovine Lens Gamma-Crystallin by Homocysteinylation; The Pathomechanism Underlying Cataract Development During Hyperhomocysteinimia.
Topics: Animals; Cataract; Cattle; Circular Dichroism; Disulfides; gamma-Crystallins; Homocysteine; Hydrophobic and Hydrophilic Interactions; Hyperhomocysteinemia; Lens, Crystalline; Protein Aggregates | 2016 |
N- and S-homocysteinylation reduce the binding of human serum albumin to catechins.
Topics: Aminoacylation; Catechin; Cysteine; Electrophoresis, Capillary; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Ligands; Lysine; Protein Processing, Post-Translational; Serum Albumin; Serum Albumin, Human | 2017 |
Involvement of homocysteine, homocysteine thiolactone, and paraoxonase type 1 (PON-1) in the etiology of defective human sperm function.
Topics: Aryldialkylphosphatase; Homocysteine; Humans; Infertility, Male; Male; Sperm Motility; Spermatozoa | 2016 |
Berberine activates peroxisome proliferator-activated receptor gamma to increase atherosclerotic plaque stability in Apoe
Topics: Animals; Apolipoproteins E; Berberine; Carotid Arteries; Cell Survival; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Homocysteine; Hyperhomocysteinemia; Male; Mice; Mice, Knockout; Oxidative Stress; Plaque, Atherosclerotic; PPAR gamma | 2016 |
Homocysteine pre-treatment increases redox capacity in both endothelial and tumor cells.
Topics: Antioxidants; Cell Line, Tumor; Endothelial Cells; Homocysteine; Humans; Neoplasms; Oxidation-Reduction | 2017 |
Paraoxonases-1, -2 and -3: What are their functions?
Topics: Animals; Aryldialkylphosphatase; Astrocytes; Carotid Artery Diseases; Cells, Cultured; Clopidogrel; Endoplasmic Reticulum; Female; Genotype; Homocysteine; Humans; Inflammation; Lipid Metabolism; Lipoproteins, HDL; Male; Mice; Mice, Knockout; Mitochondria; Neurons; Organophosphorus Compounds; Oxidative Stress; Platelet Aggregation Inhibitors; Quorum Sensing; Ticlopidine | 2016 |
Extracted Anaxagorea luzonensis A. Gray Restored Impairment of Endothelium-Dependent Vasorelaxation Induced by Homocysteine Thiolactone in Rat Aortic Rings.
Topics: Animals; Annonaceae; Aorta, Thoracic; Endothelium, Vascular; Homocysteine; Male; Plant Extracts; Rats; Rats, Wistar; Vasodilation | 2015 |
Quantification of urinary S- and N-homocysteinylated protein and homocysteine-thiolactone in mice.
Topics: Animals; Chromatography, High Pressure Liquid; Cystathionine beta-Synthase; Homocysteine; Mice; Urinalysis | 2016 |
Modulation of paraoxonase 1 (PON1) activity and protein N-homocysteinylation by bisphosphonates in rats.
Topics: Animals; Aryldialkylphosphatase; Diphosphonates; Homocysteine; Male; Paraoxon; Phenylacetates; Rats, Wistar | 2016 |
N-Homocysteinylation impairs collagen cross-linking in cystathionine β-synthase-deficient mice: a novel mechanism of connective tissue abnormalities.
Topics: Animals; Collagen Type I; Collagen Type I, alpha 1 Chain; Connective Tissue; Cystathionine beta-Synthase; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Lysine; Mice, Knockout; Peptides | 2016 |
Processes of plasma protein N-homocysteinylation in multiple sclerosis.
Topics: Adult; Aryldialkylphosphatase; Biomarkers; Blood Proteins; Female; Homocysteine; Humans; Male; Middle Aged; Multiple Sclerosis; Serum Albumin | 2017 |
Dehomocysteinylation is catalysed by the sirtuin-2-like bacterial lysine deacetylase CobB.
Topics: Animals; Bacterial Proteins; Carboxylic Ester Hydrolases; Cattle; HEK293 Cells; Histone Deacetylases; Homocysteine; Humans; Immunoblotting; Kinetics; Lysine; Mice; Models, Chemical; Molecular Structure; Mutation; NIH 3T3 Cells; Protein Processing, Post-Translational; Serum Albumin, Bovine; Sirtuin 2 | 2016 |
Protective Effects of Acetylation on the Pathological Reactions of the Lens Crystallins with Homocysteine Thiolactone.
Topics: Acetylation; alpha-Crystallins; Animals; Cattle; Circular Dichroism; Homocysteine; Humans; Lens, Crystalline; Microscopy, Electron, Scanning; Protein Conformation; Protein Processing, Post-Translational; Protein Stability | 2016 |
Homocysteine & its metabolite homocysteine-thiolactone & deficiency of copper in patients with age related macular degeneration - A pilot study.
Topics: Aged; Copper; Female; Glutathione; Homocysteine; Humans; Macular Degeneration; Male; Middle Aged; Oxidative Stress; Thiobarbituric Acid Reactive Substances | 2016 |
Is hyperhomocysteinemia a causal factor for heart failure? The impact of the functional variants of MTHFR and PON1 on ischemic and non-ischemic etiology.
Topics: Aged; Aryldialkylphosphatase; Cardiomyopathy, Dilated; Causality; Female; Genetic Predisposition to Disease; Heart Failure; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Ischemia; Poland; Risk Factors; Stroke Volume | 2017 |
Conformational status of cytochrome c upon N-homocysteinylation: Implications to cytochrome c release.
Topics: Animals; Apoptosis; Cardiolipins; Cattle; Circular Dichroism; Cytochromes c; Electron Spin Resonance Spectroscopy; Heme; Homocysteine; Iron; Ligands; Methionine; Myocardium; Oxygen; Peroxidase; Peroxidases; Protein Conformation; Protein Processing, Post-Translational; Spectrophotometry, Ultraviolet | 2017 |
The effect of N-acetylcysteine supplementation on serum homocysteine levels and hepatic and renal oxidative stress in homocysteine thiolactone-treated rats.
Topics: Acetylcysteine; Animals; Antioxidants; Dietary Supplements; Free Radical Scavengers; Glutathione; Homocysteine; Kidney; Kidney Function Tests; Lipid Peroxidation; Liver; Liver Function Tests; Male; Malondialdehyde; Oxidants; Oxidation-Reduction; Oxidative Stress; Radiation-Protective Agents; Rats; Rats, Wistar | 2017 |
Structural changes of fibrinogen molecule mediated by the N-homocysteinylation reaction.
Topics: Electrophoresis, Capillary; Electrophoresis, Gel, Two-Dimensional; Fibrinogen; Homocysteine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Hyperhomocysteinemia; Isoelectric Focusing | 2018 |
Excess homocysteine upregulates the NRF2-antioxidant pathway in retinal Müller glial cells.
Topics: Animals; Antioxidant Response Elements; Cell Survival; Ependymoglial Cells; Glutathione; Homocysteine; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Radiation-Protective Agents; Up-Regulation | 2019 |
COMMERCIAL EXTRACT FROM ARONIA AS A MODULATOR OF ADHESIVE PROPERTIES OF FIBRINOGEN TREATED WITH HOMOCYSTEINE AND ITS THIOLACTONE IN VITRO.
Topics: Blood Platelets; Fibrinogen; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; In Vitro Techniques; Photinia; Plant Extracts; Platelet Adhesiveness; Polyphenols | 2016 |
Modification of erythropoietin structure by N-homocysteinylation affects its antiapoptotic and proliferative functions.
Topics: Apoptosis; Cell Proliferation; Cells, Cultured; Erythropoietin; Homocysteine; Humans; Lysine; Megakaryocytes; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Secondary | 2018 |
Elevated H3K79 homocysteinylation causes abnormal gene expression during neural development and subsequent neural tube defects.
Topics: Adult; Animals; Brain; Chick Embryo; DNA (Cytosine-5-)-Methyltransferases; DNA Helicases; DNA Methyltransferase 3B; Female; HEK293 Cells; Histones; Homocysteine; Humans; Male; Neural Tube Defects; Nuclear Proteins; Transcription Factors; Young Adult | 2018 |
Serum paraoxonase 1 activity and protein N-homocysteinylation in primary human endometrial cancer.
Topics: Aged; Aryldialkylphosphatase; Case-Control Studies; Endometrial Neoplasms; Female; Homocysteine; Humans; Lymphatic Metastasis; Middle Aged; Neoplasm Invasiveness; Prognosis; Protein Processing, Post-Translational | 2018 |
Application of GC-MS technique for the determination of homocysteine thiolactone in human urine.
Topics: Formates; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Limit of Detection; Linear Models; Liquid-Liquid Extraction; Reproducibility of Results | 2018 |
N-Acyl l-Homocysteine Thiolactones Are Potent and Stable Synthetic Modulators of the RhlR Quorum Sensing Receptor in Pseudomonas aeruginosa.
Topics: Bacterial Proteins; Dose-Response Relationship, Drug; Homocysteine; Pseudomonas aeruginosa; Quorum Sensing | 2019 |
A chemoselective reaction between protein N-homocysteinylation and azides catalyzed by heme(ii).
Topics: Animals; Azides; Biotin; Catalysis; Cattle; Heme; Homocysteine; Hydrogen-Ion Concentration; Myoglobin; Peptides; Protein Processing, Post-Translational; Proteins; Serum Albumin, Bovine; Tandem Mass Spectrometry; Temperature | 2019 |
Hydrolysis of homocysteine thiolactone results in the formation of Protein-Cys-S-S-homocysteinylation.
Topics: Cysteine; Homocysteine; Humans; Hydrolysis; Protein Binding; Serum Albumin, Human; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2019 |
Oxidized LDL, homocysteine, homocysteine thiolactone and advanced glycation end products act as pro-oxidant metabolites inducing cytokine release, macrophage infiltration and pro-angiogenic effect in ARPE-19 cells.
Topics: Cells, Cultured; Cytokines; Glycation End Products, Advanced; Homocysteine; Humans; Lipoproteins, LDL; Macrophages; Macular Degeneration; Neovascularization, Pathologic; Oxidative Stress; Retinal Pigment Epithelium | 2019 |
Determination of homocysteine thiolactone in human urine by capillary zone electrophoresis and single drop microextraction.
Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Healthy Volunteers; Homocysteine; Humans; Liquid Phase Microextraction; Time Factors | 2020 |
Higher Levels of Low Molecular Weight Sulfur Compounds and Homocysteine Thiolactone in the Urine of Autistic Children.
Topics: Adolescent; Autistic Disorder; Child; Child, Preschool; Cysteine; Dipeptides; Female; Homocysteine; Humans; Male; Molecular Weight; Sulfur Compounds | 2020 |
Human Serum Albumin Labelled with Sterically-Hindered Nitroxides as Potential MRI Contrast Agents.
Topics: Carboxylic Acids; Cell Death; Contrast Media; Electron Spin Resonance Spectroscopy; Homocysteine; Humans; Kinetics; Magnetic Resonance Imaging; Nitrogen Oxides; Phantoms, Imaging; Protein Structure, Secondary; Serum Albumin, Human; Staining and Labeling | 2020 |
Copper, heart disease and homocysteine thiolactone.
Topics: Copper; Heart Diseases; Homocysteine; Humans | 2021 |
Copper deficiency, heart disease and homocysteine thiolactone.
Topics: Copper; Heart Diseases; Homocysteine; Humans | 2021 |
Quantification of homocysteine thiolactone in human saliva and urine by gas chromatography-mass spectrometry.
Topics: Adult; Aged; Female; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Linear Models; Male; Middle Aged; Reproducibility of Results; Saliva; Sensitivity and Specificity; Young Adult | 2020 |
Headspace study of chiral interconversion of N-acetyl-homocysteine thiolactones.
Topics: Chemistry Techniques, Analytical; Chromatography, Gas; Homocysteine; Kinetics; Stereoisomerism; Thermodynamics | 2021 |
A quantitative method for the assessment of homocysteine thiolactonase enzyme activity.
Topics: Copper; HEPES; Homocysteine; Humans; Phenanthrolines; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2021 |
Thiolactomide: A New Homocysteine Thiolactone Derivative from
Topics: Cell Line, Tumor; Cell Survival; Homocysteine; Humans; Hydrogen Peroxide; Molecular Structure; Neuroprotective Agents; Oxidopamine; Soil Microbiology; Streptomyces | 2021 |
Homocysteine-Thiolactone Modulates Gating of Mitochondrial Voltage-Dependent Anion Channel (VDAC) and Protects It from Induced Oxidative Stress.
Topics: Animals; Homocysteine; Hydrogen Peroxide; Mitochondria; Oxidative Stress; Rats; Voltage-Dependent Anion Channels | 2022 |
Single-Step Hydrolysis and Derivatization of Homocysteine Thiolactone Using Zone Fluidics: Simultaneous Analysis of Mixtures with Homocysteine Following Separation by Fluorosurfactant-Modified Gold Nanoparticles.
Topics: Gold; Homocysteine; Hydrolysis; Metal Nanoparticles | 2022 |
Functionally active cross-linked protein oligomers formed by homocysteine thiolactone.
Topics: Homocysteine; Humans; Proteins | 2023 |
Conundrum of dehydroascorbic acid and homocysteine thiolactone reaction products: Structural characterization and effect on peptide and protein N-homocysteinylation.
Topics: Dehydroascorbic Acid; Homocysteine; Humans; Neurodegenerative Diseases; Peptides | 2023 |