homocysteine has been researched along with serine in 132 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 70 (53.03) | 18.7374 |
| 1990's | 9 (6.82) | 18.2507 |
| 2000's | 32 (24.24) | 29.6817 |
| 2010's | 17 (12.88) | 24.3611 |
| 2020's | 4 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Wiederanders, B; Willhardt, I | 1 |
| Beaton, JM; Bradley, RJ; Smythies, JR | 1 |
| Canfield, CJ; McCormick, GJ; Smith, CC | 2 |
| Hems, R; Krebs, HA; Viña, J | 1 |
| Chanarin, I; Taguchi, H | 1 |
| Hems, R; Krebs, HA | 1 |
| Beaton, JM | 1 |
| Burton, EG; Sallach, HJ | 1 |
| Fernandez-Checa, JC; Kaplowitz, N; Maddatu, T; Ookhtens, M | 1 |
| Schalinske, KL; Steele, RD | 1 |
| Allen, IC; Grieve, A; Griffiths, R | 1 |
| Finkelstein, JD; Harris, BJ; Martin, JJ | 1 |
| Boss, GR | 1 |
| Dudman, NP; Tyrrell, PA; Wilcken, DE | 2 |
| Brattström, LE; Hardebo, JE; Hultberg, BL | 1 |
| Chatagner, F; de Billy, G; Ipaktchi, M; Lefauconnier, JM; Portemer, C | 1 |
| Cheah, KS; Watkins, JC | 1 |
| Beaton, JM; Bradley, RJ; Bridgers, WF; McClain, LD; Pegram, GV; Smythies, JR | 1 |
| Botsford, JL; Parks, LW | 2 |
| Josephs, JA; Magazino, J; Parker, CM; Sprince, H | 1 |
| Paszewski, A; Pieniazek, N; Stepień, PP | 1 |
| Grabski, J; Paszewski, A | 1 |
| Collins, JM; Monty, KJ | 1 |
| Foster, MA; Pattison, JR; Salem, AR | 1 |
| Foster, MA; Salem, AR | 1 |
| Conerly, EB; Mudd, SH; Uhlendorf, BW | 1 |
| Hill, LJ; Martin, WG | 1 |
| Erbe, RW; Rosenblatt, DS | 1 |
| Florentiev, VL; Goryachenkova, EV; Polyakova, LA; Yefremova, LL | 1 |
| Beratis, NG; Fleisher, LD; Gaull, GE; Hirschhorn, K; Tallan, HH | 1 |
| Boguslawski, J; Klopotowski, T; Walczak, W | 1 |
| Bertino, JR; Hillcoat, BL | 1 |
| Harada, T; Murooka, Y; Seto, K | 1 |
| Corcino, JJ; Herbert, V; Waxman, S | 1 |
| Carr, HS; Rosenkranz, HS; Zyroff, J | 1 |
| Dawes, J; Foster, MA | 1 |
| Smith, DA | 1 |
| Braunstein, AE; Goryachenkova, EV; Tolosa, EA; Willhardt, IH; Yefremova, LL | 1 |
| Wainwright, T | 2 |
| Cauthen, SE; Foster, MA; Woods, DD | 1 |
| Schlesinger, S | 1 |
| Josephs, JA; Parker, CM; Sprince, H | 1 |
| Abbott, EH; Martell, AE | 1 |
| Cherest, H; Robichon-Szulmajster, H; Talbot, G | 1 |
| Gilmour, DG; Manowitz, P; Racevskis, J | 1 |
| Hammar, UB; Strecker, HJ; Volpe, P | 1 |
| Foster, MA; Salem, AR; Wilson, RH | 1 |
| Giovanelli, J; Mudd, SH | 2 |
| Spence, KD | 1 |
| Brown, FC; Gordon, PH | 2 |
| Cherest, H; Eichler, F; Robichon-Szulmajster, H | 1 |
| Braunstein, AE; Goryachenkova, EV; Lac, ND | 1 |
| Cossins, EA; Sinha, SK | 1 |
| Brown, FC; Mallady, BJ; Roszell, JA | 1 |
| Landi, L; Marchetti, M; Pasquali, P | 1 |
| Crooks, SL; Freund, RK; Johnson, RL; Koerner, JF; Robinson, MB | 1 |
| Abeles, RH; Borcsok, E | 1 |
| Bostom, AG; Hartman, W; Lapane, KL; Miller, JW; Nadeau, M; Prior, R; Seyoum, E; Shemin, D; Sutherland, P; Wilson, PW | 1 |
| Bannai, S; Fujiwara, K; Sagara, J; Sato, H | 1 |
| Bukovska, G; Kery, V; Kraus, JP | 2 |
| Dawson, PA; Dudman, NP; Gordon, RB; Guo, XW; Wilcken, DE | 1 |
| Brosnan, JT; Brosnan, ME; House, JD | 1 |
| Burnett, JP; Clark, B; Cockerham, SL; Evans, N; Kingston, AE; Lodge, D; Lowndes, J; Mayne, NG; Tomlinson, R | 1 |
| Bottiglieri, T; Charles, HC; Gray, L; Hyland, K; Jaeken, J; Kahler, SG; Lazeyras, F; Van Hove, JL; Zeisel, SH | 1 |
| Cuskelly, GJ; Gregory, JF; Martinez, M; Toth, JP; Williamson, J | 1 |
| Bruno, S; Burkhard, P; Janosik, M; Kraus, JP; Mozzarelli, A; Schiaretti, F | 1 |
| Cook, RJ | 1 |
| Baumgartner, TG; Cuskelly, GJ; Gregory, JF; Shane, B; Stacpoole, PW; Toth, JP | 1 |
| Fowler, B | 1 |
| Dunn, MF; Jhee, KH; McPhie, P; Miles, EW; Niks, D | 2 |
| Baumgartner, TG; Cuskelly, GJ; Gregory, JF; Stacpoole, PW; Williamson, J | 1 |
| Hawkesford, MJ; Warrilow, AG | 1 |
| Arroo, RR; Baguet, E; Garlick, AP; Girard, S; Lebreton, J; Mesnard, F; Ratcliffe, G; Robins, RJ; Roscher, A | 1 |
| Banerjee, R; Taoka, S | 1 |
| de Meer, K; Finglas, P; Smulders, Y; Stam, F; Stehouwer, CD; van den Akker, JT | 1 |
| Aitken, SM; Kirsch, JF | 1 |
| Fowler, B; Kozich, V; Pristoupilová, K; Suormala, T; Zavad'áková, P; Zavadakova, P; Zeman, J | 1 |
| Ishikawa, K; Mino, K | 1 |
| ALEXANDER, GJ | 1 |
| MULLER, P | 1 |
| MARCHETTI, M; MORUZZI, G; VIVIANI, R | 1 |
| LANGER, BW | 1 |
| ROWBURY, RJ; WOODS, DD | 1 |
| FLAVIN, M; SLAUGHTER, C | 1 |
| KORITZ, SB; MUNCK, A | 1 |
| AURAND, LW; KIZER, DE; SPECK, ML | 1 |
| Bailey, LB; Coats, BS; Davis, SR; Gregory, JF; Kick, LS; Quinlivan, EP; Shane, B; Stacpoole, PW; Williamson, J | 1 |
| Davis, SR; Gregory, JF; Mackey, AD; Townsend, JH | 1 |
| Castro, C; Garrow, TA; Leclerc, D; Lussier-Cacan, S; Mar, MH; Rozen, R; Schwahn, BC; Wendel, U; Zeisel, SH | 1 |
| Boelsma, E; Katan, MB; Olthof, MR; Steenge, GR; van Vliet, T; Verhoef, P | 1 |
| Bell, CE; Hu, X; Pei, D; Rajan, R; Zhu, J | 1 |
| Coats, BS; Davis, SR; Gregory, JF; Quinlivan, EP; Scheer, JB; Stacpoole, PW | 1 |
| Bailey, LB; Capdevila, A; Coats, BS; Davis, SR; Ghandour, H; Gregory, JF; Quinlivan, EP; Selhub, J; Shane, B; Shelnutt, KP; Shuster, JJ; Stacpoole, PW; Wagner, C | 1 |
| Arseth, O; Kvalheim, G; Ueland, PM; Windelberg, A | 1 |
| Blanaru, M; Bloch, B; Ermilov, M; Heresco-Levy, U; Javitt, DC; Kremer, I; Neeman, G | 1 |
| Baroni, S; Daloiso, PD; De Sole, P; Fasanella, S; Giardina, B; Minucci, A; Neri, P; Persichilli, S; Scribano, D; Zappacosta, B | 1 |
| Amao, M; Kawamata, Y; Kimura, T; Kodama, R; Sakai, R; Toue, S | 1 |
| Auger, S; Barzu, O; Danchin, A; Hullo, MF; Martin-Verstraete, I; Soutourina, O; Yvon, M | 1 |
| Luo, Y; Wang, J; Yang, X; Zhou, X | 1 |
| Matsumoto, Y; Morita, T; Ohuchi, S; Sugiyama, K | 2 |
| Agrawal, N; Banerjee, R | 1 |
| Mori, M; Morita, T; Ohuchi, S; Sugiyama, K | 1 |
| Nakahara, A; Ozaki, S; Sakaguchi, C; Yoshiya, M | 1 |
| Gould, TJ; Kruger, WD; Portugal, GS; Pratico, D; Wang, H; Zhuo, JM | 1 |
| Goossens, L | 1 |
| Liu, Y; Liu, YQ; Mori, M; Morita, T; Sugiyama, K | 1 |
| Banerjee, R; Yadav, PK | 1 |
| Hall, CD; Katritzky, AR; Oliferenko, AA; Panda, SS | 1 |
| Choi, HS; Choi, YJ; Kim, SK; Kwak, HC; Lee, BH; Sim, WC; Yin, HQ | 1 |
| Berge, RK; Bjørndal, B; Lysne, V; Nordrehaug, JE; Nygård, O; Skorve, J; Vik, R | 1 |
| Chi, YY; Coats, B; Gregory, JF; Midttun, Ø; Ralat, M; Rios-Avila, L; Stacpoole, PW; Ueland, PM | 1 |
| Adams, PD; Labuschagne, CF; Maddocks, OD; Vousden, KH | 1 |
| Choi, YJ; Han, I; Jung, SH; Kim, DG; Lee, BH; Lee, KY; Lee, W; Oh, SH; Sim, WC | 1 |
| An, YM; Cong, X; Dou, D; Feng, H; Wu, LL; Zhang, XZ; Zhao, Q | 1 |
| He, L; Wu, C; Wu, X; Yin, Y; Zhang, Y; Zhou, X | 1 |
| Gregory, JF; Kent, J; Kožich, V; Kraus, JP; Krijt, J; Křížková, M; Majtan, T; Ralat, MA; Sokolová, J | 1 |
| Abdul Rehman, SA; Ali, MF; Devi, S; Gourinath, S; Tarique, KF | 1 |
| Haufroid, M; Leherte, L; Mirgaux, M; Wouters, J | 1 |
| Hayes, A; Kruzliak, P; Rai, S; Smith, RM; Zulli, A | 1 |
| Astegno, A; Conter, C; Dominici, P; Fernández-Rodríguez, C; Fruncillo, S; Martínez-Cruz, LA | 1 |
| Danshiitsoodol, N; Ezumi, Y; Izuhara-Kihara, H; Kumagai, T; Matoba, Y; Noda, M; Oda, K; Sugiyama, M; Yasutake, C; Yoshida, T | 1 |
| Stipanuk, MH | 1 |
| Cai, Y; Deng, Z; Hao, H; Li, S; Shi, C; Song, J; Yang, Q; Zhuang, G | 1 |
7 review(s) available for homocysteine and serine
| Article | Year |
|---|---|
Methylation & schizophrenia.
Topics: Amines; Amino Acids; Animals; Behavior, Animal; Catecholamines; Cats; Cystathionine; Cysteine; Dihydroxyphenylalanine; Drug Tolerance; Hallucinogens; Homocysteine; Humans; Indoles; Methionine; Methylation; Mice; Schizophrenia; Serine; Taurine | 1975 |
Regulation of dihydrofolate reductase and other folate-requiring enzymes.
Topics: Alcohol Oxidoreductases; Animals; Enzyme Induction; Erythrocytes; Escherichia coli; Folic Acid; Folic Acid Antagonists; Formates; Guinea Pigs; Homocysteine; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Leukemia; Leukocytes; Ligases; Methotrexate; Oxidoreductases; Rats; Salmonella typhimurium; Serine; Streptococcus; Tetrahydrofolate Dehydrogenase | 1968 |
Drugs, toxins and dietary amino acids affecting vitamin B12 or folic acid absorption or utilization.
Topics: Amino Acids; Anemia, Macrocytic; Contraceptives, Oral; Diet; DNA; Ethanol; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Glycine; Homocysteine; Humans; Malabsorption Syndromes; Methionine; Pharmacology; Serine; Toxins, Biological; Vitamin B 12 | 1970 |
S-amino acid metabolism and its regulation in Escherichia coli and Salmonella typhimurium.
Topics: Amino Acids; Aspartic Acid; Chromosome Mapping; Chromosomes, Bacterial; Conjugation, Genetic; Cysteine; Escherichia coli; Feedback; Genes; Genes, Regulator; Homocysteine; Methionine; Methylation; Salmonella; Salmonella typhimurium; Serine; Sulfates; Transduction, Genetic | 1971 |
The folate cycle and disease in humans.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5,10-Methylenetetrahydrofolate Reductase (FADH2); Aminohydrolases; Biological Transport, Active; Folic Acid; Formate-Tetrahydrofolate Ligase; Histidine; Homeostasis; Homocysteine; Humans; Intestinal Mucosa; Kidney Diseases; Metabolism, Inborn Errors; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Multienzyme Complexes; Oxidoreductases; Polyglutamic Acid; Purine Nucleotides; Serine; Tetrahydrofolates | 2001 |
In vivo stable isotope measurements of methyl metabolism: applications in pathophysiology and interventions.
Topics: Deuterium Oxide; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infusions, Intravenous; Kidney Failure, Chronic; Methionine; Methylation; Serine; Tomography, Emission-Computed; Tritium | 2002 |
Metabolism of Sulfur-Containing Amino Acids: How the Body Copes with Excess Methionine, Cysteine, and Sulfide.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Cystathionine beta-Synthase; Cysteine; Glycine N-Methyltransferase; Homocysteine; Humans; Hydrogen Sulfide; Liver; Methionine; S-Adenosylmethionine; Serine; Sulfides; Sulfur; Thiosulfates | 2020 |
2 trial(s) available for homocysteine and serine
| Article | Year |
|---|---|
Deficiencies of folate and vitamin B(6) exert distinct effects on homocysteine, serine, and methionine kinetics.
Topics: Adult; Amino Acids; Diet; Folic Acid Deficiency; Homocysteine; Humans; Leucine; Male; Methionine; Methylation; Nutritional Physiological Phenomena; Nutritional Status; Polymorphism, Genetic; Serine; Vitamin B 6 Deficiency | 2001 |
Dietary serine and cystine attenuate the homocysteine-raising effect of dietary methionine: a randomized crossover trial in humans.
Topics: Adult; Analysis of Variance; Area Under Curve; Cardiovascular Diseases; Cross-Over Studies; Cystine; Dietary Proteins; Fasting; Homocysteine; Humans; Male; Methionine; Serine | 2004 |
123 other study(ies) available for homocysteine and serine
| Article | Year |
|---|---|
Activity staining of cystathionine-beta-synthetase and related enzymes.
Topics: Electrophoresis, Disc; Homocysteine; Hydro-Lyases; Lead; Saccharomyces cerevisiae; Serine; Staining and Labeling; Sulfides | 1975 |
The behavioral effects of L-methionine and related compounds in rats and mice.
Topics: Animals; Avoidance Learning; Behavior, Animal; Betaine; Brain; Brain Chemistry; Circadian Rhythm; Conditioning, Operant; Cysteine; Electroencephalography; Eye Movements; Histidine; Homocysteine; Methionine; Mice; Mice, Inbred C57BL; Niacinamide; Rats; Serine; Sleep; Sleep, REM; Wakefulness | 1975 |
Plasmodium knowlesi: in vitro biosynthesis of methionine and thymidylic acid.
Topics: Animals; Betaine; Cells, Cultured; Choline; Erythrocytes; Folic Acid; Formaldehyde; Formyltetrahydrofolates; Haplorhini; Histidine; Homocysteine; Macaca mulatta; Methionine; Plasmodium; Sarcosine; Serine; Thymidine Monophosphate; Thymine Nucleotides | 1977 |
Maintenance of glutathione content is isolated hepatocyctes.
Topics: Animals; Cell Separation; Cysteine; Female; Glutathione; Homocysteine; In Vitro Techniques; Liver; Methionine; Rats; Serine | 1978 |
The effect of homocysteine, methionine, serine and glycine on DNA synthesis by human normoblastic and megaloblastic bone marrow cells.
Topics: Bone Marrow Cells; Cell Survival; Deoxyuridine; DNA; Erythrocytes, Abnormal; Glycine; Homocysteine; Humans; Megaloblasts; Methionine; Serine; Thymidine | 1978 |
Plasmodium knowlesi: in vitro biosynthesis of methionine.
Topics: Animals; Erythrocytes; Haplorhini; Homocysteine; In Vitro Techniques; Macaca mulatta; Methionine; Plasmodium; Serine; Tetrahydrofolates; Thymidine Monophosphate | 1976 |
The regulation of the degradation of methionine and of the one-carbon units derived from histidine, serine and glycine.
Topics: Animals; Carbon Dioxide; Enzyme Activation; Folic Acid; Formates; Formiminoglutamic Acid; Gluconeogenesis; Glucose; Glycine; Histidine; Homocysteine; In Vitro Techniques; Liver; Methionine; Oxidoreductases Acting on CH-NH Group Donors; Perfusion; Rats; Serine; Tetrahydrofolates | 1976 |
Methylenetetrahydrofolate reductase in the rat central nervous system: intracellular and regional distribution.
Topics: Alcohol Oxidoreductases; Animals; Brain; Chromatography, Ion Exchange; Homocysteine; Liver; Methyltransferases; Microsomes; Organ Specificity; Rats; Serine; Subcellular Fractions; Synaptosomes; Tetrahydrofolates | 1975 |
Inhibition of GSH efflux from rat liver by methionine: effects of GSH synthesis in cells and perfused organ.
Topics: Alkynes; Amino Acids; Animals; Cells, Cultured; Cysteine; Glutathione; Glycine; Homocysteine; Kinetics; Liver; Male; Methionine; Pargyline; Perfusion; Rats; Rats, Inbred Strains; Serine | 1990 |
Quantitation of carbon flow through the hepatic folate-dependent one-carbon pool in rats.
Topics: Animals; Biological Transport; Carbon; Homocysteine; Liver; Male; Methionine; Rats; Rats, Inbred Strains; Serine; Tetrahydrofolates; Time Factors | 1989 |
Differential changes in the content of amino acid neurotransmitters in discrete regions of the rat brain prior to the onset and during the course of homocysteine-induced seizures.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Corpus Striatum; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hippocampus; Homocysteine; Hypothalamus; Inferior Colliculi; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Substantia Nigra; Taurine; Tissue Distribution | 1986 |
Effect of dietary cystine on methionine metabolism in rat liver.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Cystine; Dietary Proteins; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Serine | 1986 |
Cobalamin inactivation decreases purine and methionine synthesis in cultured human lymphoblasts.
Topics: Folic Acid; Homocysteine; Humans; Lymphocytes; Methionine; Nitrous Oxide; Oxidation-Reduction; Purines; Serine; Vitamin B 12 | 1986 |
Homocysteinemia: depressed plasma serine levels.
Topics: Adult; Betaine; Carbon-Oxygen Lyases; Child, Preschool; Folic Acid; Glycine; Homocysteine; Humans; Isoleucine; Kidney Transplantation; Lyases; Male; Serine | 1987 |
Folic acid responsive postmenopausal homocysteinemia.
Topics: Adult; Aging; Cystine; Dipeptides; Fasting; Female; Folic Acid; Glycine; Homocysteine; Humans; Male; Menopause; Methionine; Middle Aged; Serine | 1985 |
Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients.
Topics: Adolescent; Adult; Betaine; Child; Cystathionine beta-Synthase; Cysteine; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Hydro-Lyases; Male; Methionine; Middle Aged; Pyridoxine; Serine | 1985 |
Redistribution of pyridoxal phosphate in the male rat liver as a result of repeated injections of hydrocortisone.
Topics: Alanine Transaminase; Animals; Aspartic Acid; Carboxy-Lyases; Cystathionine; Cysteine; Dose-Response Relationship, Drug; Homocysteine; Homoserine; Hydro-Lyases; Hydrocortisone; L-Serine Dehydratase; Liver; Lyases; Male; Pyridoxal Phosphate; Rats; Seasons; Serine; Time Factors; Tyrosine Transaminase | 1973 |
Further syntheses in the study of structure-activity relationships of neuropharmacologically active amino acids.
Topics: Amino Alcohols; Animals; Aspartic Acid; Cats; Central Nervous System; Choline; Cysteine; Homocysteine; Muscle Spindles; Neurons; Serine; Sulfinic Acids | 1965 |
A study of the behavioral disruption of mice induced by l-methionine and related compounds.
Topics: Amphetamine; Animals; Behavior, Animal; Betaine; Chlorpromazine; Cystathionine; Folic Acid; Histidine; Homocysteine; Homoserine; Male; Mescaline; Methionine; Mice; N,N-Dimethyltryptamine; Niacinamide; Serine; Social Behavior | 1974 |
Role of S-adenosylmethionine in methionine biosynthesis in yeast.
Topics: Adenine Nucleotides; Carbon Isotopes; Cell-Free System; Culture Media; Escherichia coli; Ethanol; Flavin-Adenine Dinucleotide; Hexosephosphates; Homocysteine; Magnesium; Methionine; NAD; Nucleosides; Pyridoxal Phosphate; Saccharomyces; Serine | 1967 |
Convulsant activity of homocysteine and other short-chain mercaptoacids: protection therefrom.
Topics: Animals; Betaine; Central Nervous System Stimulants; Cysteine; Glycine; Homocysteine; Male; Methionine; Phenobarbital; Pyridoxine; Rats; Serine | 1969 |
An Aspergillus nidulans mutant lacking cystathionine -synthase: identity of L-serine sulfhydrylase with cystathionine -synthase and its distinctness from O-acetyl-L-serine sulfhydrylase.
Topics: Aspergillus; Aspergillus nidulans; Carbon Isotopes; Cell-Free System; Culture Media; Cystathionine; Cysteine; Homocysteine; Hydro-Lyases; Molecular Weight; Mutation; Selenium; Serine; Species Specificity | 1973 |
Studies on beta-cystathionase and omicron-acetylhomoserine sulfhydrylase as the enzymes of alternative methionine biosynthetic pathways in Aspergillus nidulans.
Topics: Acetylation; Aspergillus; Aspergillus nidulans; Cystathionine; Enzyme Repression; Homocysteine; Homoserine; Hydrogen Sulfide; Lyases; Methionine; Serine | 1973 |
The cysteine desulfhydrase of Salmonella typhimurium. Kinetic and catalytic properties.
Topics: Binding Sites; Cell-Free System; Centrifugation, Density Gradient; Chromatography, Gel; Cystathionine; Cysteine; Drug Stability; Enzyme Activation; Enzyme Induction; Homocysteine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Lyases; Mathematics; Mercaptoethanol; Methionine; Mutation; Salmonella typhimurium; Serine; Stereoisomerism; Structure-Activity Relationship; Sulfhydryl Compounds | 1973 |
Folic acid and the methylation of homocysteine by Bacillus subtilis.
Topics: Alcohol Oxidoreductases; Bacillus subtilis; Chromatography, Gel; Chromatography, Thin Layer; Cobamides; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Serine; Ultrasonics; Vitamin B 12 | 1972 |
The microbial biosynthesis of methionine.
Topics: Bacillus megaterium; Basidiomycota; Candida; Carbon Isotopes; Catalase; Escherichia coli; Homocysteine; Methionine; Methylation; Methyltransferases; Serine; Tetrahydrofolate Dehydrogenase | 1972 |
Homocystinuria: studies in tissue culture.
Topics: Culture Techniques; Fibroblasts; Heterozygote; Homocysteine; Homocystine; Homocystinuria; Humans; Hydro-Lyases; L-Serine Dehydratase; Methionine; Methyltransferases; Oxidoreductases; Parents; Proteins; Pyridoxal Phosphate; Pyridoxine; Serine; Skin; Stimulation, Chemical; Tetrahydrofolates | 1973 |
The synthesis of taurine from sulfate. V. Regulatory modifiers of the chick liver enzyme system.
Topics: Adenosine Monophosphate; Alanine; Allosteric Regulation; Animals; Chickens; Cysteine; Ethionine; Homocysteine; Liver; Methionine; Organophosphorus Compounds; S-Adenosylmethionine; Serine; Sulfinic Acids; Sulfonic Acids; Sulfur Radioisotopes; Sulfuric Acids; Sulfurtransferases; Taurine | 1973 |
Reciprocal changes in the levels of functionally related folate enzymes during the culture cycle in human fibroblasts.
Topics: Alcohol Oxidoreductases; Carbon Radioisotopes; Cell Division; Cells, Cultured; Fibroblasts; Homocysteine; Humans; Ligases; Serine; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Time Factors; Transferases | 1973 |
Interaction of pyridoxal phosphate analogues with apoenzymes of gamma-cystathionase and serine sulphhydrase.
Topics: Animals; Apoproteins; Binding Sites; Borohydrides; Chickens; Circular Dichroism; Cystathionine; Homocysteine; Hydro-Lyases; Hydrogen Sulfide; Kinetics; Liver; Lyases; Methylation; Penicillamine; Protein Binding; Pyridoxal Phosphate; Rats; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1973 |
Cystathionine synthase deficiency: heterozygote detection using cultured skin fibroblasts.
Topics: Amino Acid Metabolism, Inborn Errors; Biopsy; Cells, Cultured; Fibroblasts; Heterozygote; Homocysteine; Homozygote; Humans; Hydro-Lyases; Hydrogen-Ion Concentration; Kinetics; Pyridoxal Phosphate; Serine; Skin | 1973 |
Reversal by serine and potentiation by glycine of the inhibitory effect of 1,2,4-triazole on growth of Salmonella typhimurium.
Topics: Adenine; Amino Acids; Cysteine; Drug Resistance, Microbial; Drug Synergism; Glycine; Homocysteine; Methionine; Mutation; Salmonella typhimurium; Serine; Triazoles | 1967 |
O-alkylhomoserine and methionine biosynthesis in Corynebacterium.
Topics: Amino Acids; Corynebacterium; Culture Media; Cysteine; Escherichia coli; Homocysteine; Methionine; Serine; Threonine | 1969 |
Synergism between cysteine and alkylating agents.
Topics: Alkanes; Alkylating Agents; Anti-Bacterial Agents; Cysteine; Drug Resistance, Microbial; Drug Synergism; Escherichia coli; Homocysteine; Nitroso Compounds; Serine; Stereoisomerism; Sulfonic Acids; Urethane | 1970 |
Vitamin B 12 and methionine synthesis in Escherichia coli.
Topics: Acyltransferases; Aerobiosis; Alcohol Oxidoreductases; Anilides; Carbon Isotopes; Chromatography, Ion Exchange; Enzyme Repression; Escherichia coli; Flavin-Adenine Dinucleotide; Folic Acid; Genetics, Microbial; Homocysteine; Homoserine; Kinetics; Methionine; Methyltransferases; Mutation; Serine; Succinates; Transferases; Vitamin B 12 | 1971 |
Specificity and some other properties of liver serine sulphhydrase: evidence for its identity with cystathionine -synthase.
Topics: Acetates; Alanine; Amino Acids; Animals; Catalysis; Chickens; Chlorine; Chromatography, Gel; Chromatography, Paper; Cycloserine; Cysteamine; Cysteine; Electrophoresis, Paper; Glycolates; Homocysteine; Hydro-Lyases; Hydroxylamines; Isoelectric Focusing; Kinetics; L-Serine Dehydratase; Liver; Mercaptoethanol; Nitriles; Penicillamine; Propionates; Pyridoxal Phosphate; Rats; Serine; Species Specificity; Sulfhydryl Compounds; Sulfides; Sulfuric Acids; Thioglycolates | 1971 |
Pyridoxine, pantothenate and methionine effects of H2S formation by Saccharomyces cerevisiae.
Topics: Culture Media; Homocysteine; Hydrogen; Methionine; Pantothenic Acid; Pyridoxine; Saccharomyces; Serine; Sulfides | 1969 |
Methionine synthesis by extracts of Salmonella typhimurium.
Topics: Alcohol Oxidoreductases; Alkylation; Homocysteine; In Vitro Techniques; Methionine; Molecular Biology; Salmonella typhimurium; Serine; Vitamin B 12 | 1966 |
Inhibition of growth of Escherichia coli and of homoserine O-transsuccinylase by alpha-methylmethionine.
Topics: Amino Acids; Enzyme Repression; Escherichia coli; Homocysteine; Methionine; Serine; Transferases; Tritium | 1967 |
Homocysteine-induced convulsions in the rat: protection by homoserine, serine, betaine, glycine and glucose.
Topics: Animals; Betaine; Glucose; Glycine; Homocysteine; Male; Rats; Seizures; Serine; Time Factors | 1969 |
Pyridoxine and pyridoxal analogs. 13. A nuclear magnetic resonance study of the condensation of polyfunctional amino acids with pyridoxal.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Cycloserine; Histidine; Homocysteine; Homocystine; Imidazoles; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Serine; Threonine | 1970 |
Role of homocysteine synthetase in an alternate route for methionine biosynthesis in Saccharomyces cerevisiae.
Topics: Amino Acids; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Gas; Crosses, Genetic; Diploidy; Ethionine; Genetics, Microbial; Haploidy; Homocysteine; Methionine; Mutation; Saccharomyces; Serine; Sulfur Isotopes; Transferases | 1970 |
A modified assay for cystathionine synthase.
Topics: Adult; Aged; Amino Acids; Animals; Carbon Isotopes; Chromatography, Paper; Homocysteine; Humans; Hydro-Lyases; L-Serine Dehydratase; Liver; Male; Methods; Pyridoxal Phosphate; Pyruvates; Rats; Serine; Taurine | 1970 |
Methionine toxicity and ornithine delta-aminotransferase in Chang's liver cells.
Topics: Arginine; Carbon Isotopes; Cell Division; Cell Line; Glycine; Histidine; Homocysteine; Humans; Kidney; Leucine; Liver; Methionine; Ornithine; Proteins; Serine; Stimulation, Chemical; Transaminases; Tryptophan; Tyrosine | 1970 |
Methylation of homocysteine in Coprinus lagopus.
Topics: Basidiomycota; Folic Acid; Homocysteine; Methionine; Methylation; Serine; Transferases | 1970 |
Hydrogen sulphide production by yeast under conditions of methionine, pantothenate or vitamin B6 deficiency.
Topics: Homocysteine; Methionine; Mutation; Pantothenic Acid; Pyridoxine; Saccharomyces; Serine; Sulfides | 1970 |
Transsulfuration in higher plants. Partial purification and properties of beta-cystathionase of spinach.
Topics: Alanine; Amino Acids; Benzoates; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Cysteine; Drug Stability; Edible Grain; Ethylmaleimide; Homocysteine; Hydro-Lyases; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; Models, Structural; Plants; Pyridoxal Phosphate; Pyruvates; Quaternary Ammonium Compounds; Serine; Species Specificity; Spectrophotometry; Stereoisomerism; Sulfates; Sulfides; Sulfur; Triticum | 1971 |
Mutation of Saccharomyces cerevisiae preventing uptake of S-adenosylmethionine.
Topics: Adenine; Carbon Isotopes; Colorimetry; Crosses, Genetic; Culture Media; Cysteine; Genetics, Microbial; Homocysteine; Methionine; Mutation; Nucleosides; S-Adenosylmethionine; Saccharomyces; Serine; Threonine | 1971 |
Cystathionine synthase from rat liver: partial purification and properties.
Topics: Amino Acids; Animals; Benzoates; Boron Compounds; Calcium Phosphates; Carbon Isotopes; Chromatography, Gel; Cysteine; Drug Stability; Electrophoresis; Enzyme Activation; Homocysteine; Hydro-Lyases; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; L-Serine Dehydratase; Liver; Mercury; Oxidation-Reduction; Protamines; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Rats; Serine; Spectrophotometry; Sulfates; Sulfides; Temperature | 1971 |
A study of L-(14C)cystathionine metabolism in the brain, kidney, and liver of pyridoxine-deficient rats.
Topics: Amino Acids; Ammonia; Animals; Biological Transport; Brain; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Cysteine; Homocysteine; Hydro-Lyases; Injections; Keto Acids; Kidney; L-Serine Dehydratase; Liver; Male; Proteins; Pyridoxine; Rats; Serine; Time Factors; Vitamin B 6 Deficiency | 1971 |
Genetic and regulatory aspects of methionine biosynthesis in Saccharomyces cerevisiae.
Topics: Alcohol Oxidoreductases; Electrophoresis; Enzyme Repression; Genes, Dominant; Heterozygote; Homocysteine; Homozygote; Kinetics; Ligases; Methionine; Molecular Biology; Nucleosides; Nucleotidyltransferases; Saccharomyces; Serine; Transferases | 1969 |
Reactions catalysed by serine sulfhydrase from chicken liver.
Topics: Animals; Chickens; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Cysteamine; Cysteine; Homocysteine; Hydro-Lyases; Liver; Mercaptoethanol; Serine; Sulfides | 1969 |
Serine transhydroxymethylase in methionine biosynthesis in Saccharomyces cerevisiae.
Topics: Cell-Free System; Enzyme Repression; Glycine; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methionine; Methylation; Saccharomyces; Serine; Transferases | 1969 |
The utilization of carbon-1 compounds by plants. II. The formation and metabolism of formate by higher plant tissues.
Topics: Edible Grain; Formates; Glycine; Glyoxylates; Homocysteine; In Vitro Techniques; Methionine; Plants; Plants, Toxic; Ricinus; Serine; Zea mays | 1965 |
The separation of rat liver serine dehydratase and cystathionine synthase.
Topics: Acetone; Amino Acids; Animals; Calcium Phosphates; Chromatography; Homocysteine; Hot Temperature; Hydro-Lyases; Hydroxyapatites; In Vitro Techniques; Liver; Pyruvates; Rats; Serine; Sulfates | 1966 |
Folic acid and biotin on the metabolism of 1 carbon unit: utilization of beta-carbon of serine for the synthesis of methionine.
Topics: Animals; Biotin; Folic Acid Deficiency; Homocysteine; In Vitro Techniques; Liver; Methionine; Rats; Serine; Vitamin B Deficiency | 1966 |
Synthesis of homocysteine and cysteine by enzyme extracts of spinach.
Topics: Amino Acids; Chromatography, Paper; Cysteine; Electrophoresis; Homocysteine; In Vitro Techniques; Methionine; Plant Extracts; Plants, Edible; Serine; Sulfides; Sulfur Isotopes; Threonine; Vegetables | 1967 |
Structure - function relationships for gamma-substituted glutamate analogues on dentate granule cells.
Topics: Aminobutyrates; Animals; Chemical Phenomena; Chemistry; Glutamates; Hippocampus; Homocysteine; In Vitro Techniques; Male; Neural Pathways; Phosphoserine; Rats; Serine | 1983 |
Mechanism of action of cystathionine synthase.
Topics: Animals; Cystathionine beta-Synthase; Homocysteine; Hydro-Lyases; Hydrogen; Kinetics; Molecular Weight; Rats; Serine; Stereoisomerism | 1982 |
Hyperhomocysteinemia and traditional cardiovascular disease risk factors in end-stage renal disease patients on dialysis: a case-control study.
Topics: Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Confidence Intervals; Embolism, Cholesterol; Female; Homocysteine; Humans; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Prevalence; Renal Dialysis; Risk Factors; Serine; Vitamin B Complex | 1995 |
Induction of cystine transport activity in mouse peritoneal macrophages by bacterial lipopolysaccharide.
Topics: Amino Acids; Animals; Biological Transport; Cells, Cultured; Cystine; Dose-Response Relationship, Drug; Female; Glutamic Acid; Glutathione; Homocysteine; Interferon-gamma; Interleukin-1; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Maleates; Mice; Mice, Inbred C57BL; Recombinant Proteins; Salmonella typhi; Serine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 1995 |
Expression of human cystathionine beta-synthase in Escherichia coli: purification and characterization.
Topics: Amino Acid Sequence; beta-Galactosidase; Chromatography, DEAE-Cellulose; Cystathionine beta-Synthase; Enzyme Activation; Escherichia coli; Factor Xa; Homocysteine; Humans; Molecular Sequence Data; Recombinant Proteins; S-Adenosylmethionine; Serine; Spectrophotometry | 1994 |
Transsulfuration depends on heme in addition to pyridoxal 5'-phosphate. Cystathionine beta-synthase is a heme protein.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Escherichia coli; Heme; Hemeproteins; Homocysteine; Humans; Kinetics; Liver; Pyridoxal Phosphate; Rats; Recombinant Proteins; Serine; Spectrophotometry; Sulfur | 1994 |
Human homocysteine catabolism: three major pathways and their relevance to development of arterial occlusive disease.
Topics: Arterial Occlusive Diseases; Betaine; Homocysteine; Homocystinuria; Humans; Male; Serine | 1996 |
Characterization of homocysteine metabolism in the rat kidney.
Topics: Animals; Chemical Fractionation; Cystathionine beta-Synthase; Homocysteine; Kidney Cortex; Kidney Tubules; Kidney Tubules, Proximal; Lyases; Male; Methylation; Rats; Rats, Sprague-Dawley; Serine; Sulfur | 1997 |
Sulphur-containing amino acids are agonists for group 1 metabotropic receptors expressed in clonal RGT cell lines.
Topics: Amino Acids, Sulfur; Animals; Cell Line; Cricetinae; Cysteic Acid; Cysteine; Glutamic Acid; Homocysteine; Humans; Mesocricetus; Neurotransmitter Agents; Phosphatidylinositols; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Serine | 1998 |
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
Topics: Amino Acid Metabolism, Inborn Errors; Benzoic Acid; Brain Diseases; Choline; Coma; Female; Glycine; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methionine; Methylation; Phosphatidylcholines; S-Adenosylmethionine; Seizures; Serine; Tetrahydrofolates | 1998 |
Vitamin B-6 deficiency in rats reduces hepatic serine hydroxymethyltransferase and cystathionine beta-synthase activities and rates of in vivo protein turnover, homocysteine remethylation and transsulfuration.
Topics: Animals; Chromatography, High Pressure Liquid; Cystathionine beta-Synthase; Diet; Glycine Hydroxymethyltransferase; Homocysteine; Liver; Male; Methylation; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Serine; Sulfurtransferases; Vitamin B 6 Deficiency | 2000 |
Functional properties of the active core of human cystathionine beta-synthase crystals.
Topics: Binding Sites; Carbon Monoxide; Cystathionine beta-Synthase; Heme; Homocysteine; Humans; Microspectrophotometry; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Pyridoxal Phosphate; Recombinant Proteins; Serine; Structure-Activity Relationship | 2001 |
Defining the steps of the folate one-carbon shuffle and homocysteine metabolism.
Topics: Folic Acid; Glycine; Homocysteine; Humans; Methionine; Methylation; Serine | 2000 |
Primed, constant infusion with [2H3]serine allows in vivo kinetic measurement of serine turnover, homocysteine remethylation, and transsulfuration processes in human one-carbon metabolism.
Topics: Adult; Amino Acids; Cytosol; Folic Acid; Homocysteine; Humans; Infusions, Intravenous; Kinetics; Male; Methionine; Methylation; Mitochondria; Nutritional Status; Pilot Projects; Serine | 2000 |
The reaction of yeast cystathionine beta-synthase is rate-limited by the conversion of aminoacrylate to cystathionine.
Topics: Cystathionine; Cystathionine beta-Synthase; Feedback; Homocysteine; Kinetics; Models, Chemical; Saccharomyces cerevisiae; Serine; Spectrophotometry | 2001 |
Yeast cystathionine beta-synthase reacts with L-allothreonine, a non-natural substrate, and L-homocysteine to form a new amino acid, 3-methyl-L-cystathionine.
Topics: Circular Dichroism; Cystathionine; Cystathionine beta-Synthase; Homocysteine; Kinetics; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Saccharomyces cerevisiae; Serine; Spectrophotometry; Substrate Specificity; Threonine | 2002 |
Modulation of cyanoalanine synthase and O-acetylserine (thiol) lyases A and B activity by beta-substituted alanyl and anion inhibitors.
Topics: Alanine; Allosteric Regulation; Allosteric Site; Anions; Carbon-Oxygen Lyases; Cysteine; Cysteine Synthase; Dimerization; Homocysteine; Hydrogen Bonding; Intracellular Membranes; Isoenzymes; Kinetics; Lyases; Mitochondria; Models, Biological; Multienzyme Complexes; Potassium Cyanide; Saccharomyces cerevisiae Proteins; Serine; Spinacia oleracea | 2002 |
Evidence for the involvement of tetrahydrofolate in the demethylation of nicotine by Nicotiana plumbaginifolia cell-suspension cultures.
Topics: Carbon Radioisotopes; Cells, Cultured; Cysteine; Homocysteine; Magnetic Resonance Spectroscopy; Methionine; Methylation; Models, Chemical; Nicotiana; Nicotine; Plant Extracts; Serine; Tetrahydrofolates | 2002 |
Stopped-flow kinetic analysis of the reaction catalyzed by the full-length yeast cystathionine beta-synthase.
Topics: Catalysis; Cystathionine; Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Heme; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae; Serine; Spectrophotometry; Time Factors | 2002 |
Kinetics of the yeast cystathionine beta-synthase forward and reverse reactions: continuous assays and the equilibrium constant for the reaction.
Topics: Catalysis; Cystathionine; Cystathionine beta-Synthase; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Recombinant Proteins; Saccharomyces cerevisiae Proteins; Sequence Deletion; Serine; Spectrophotometry; Substrate Specificity | 2003 |
CblE type of homocystinuria due to methionine synthase reductase deficiency: clinical and molecular studies and prenatal diagnosis in two families.
Topics: Adult; Anemia, Megaloblastic; Base Sequence; Cells, Cultured; Child; Chromatography, Ion Exchange; DNA; Female; Ferredoxin-NADP Reductase; Fibroblasts; Folic Acid; Homocysteine; Homocystinuria; Humans; Methionine; Molecular Sequence Data; Mutation; Prenatal Diagnosis; Reverse Transcriptase Polymerase Chain Reaction; Serine; Vitamin B 12 | 2002 |
Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
Topics: Amino Acid Sequence; Archaeal Proteins; Binding Sites; Cystathionine; Cysteine; Cysteine Synthase; Desulfurococcaceae; Dithiothreitol; Enzyme Activation; Enzyme Stability; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Sequence Homology, Amino Acid; Serine; Substrate Specificity; Sulfides; Temperature | 2003 |
Choline biogenesis II. The effect of homocysteine on serine metabolism.
Topics: Choline; Cysteine; Homocysteine; Humans; Serine | 1961 |
[Synthesis of natural sulfurated amino acids].
Topics: Amino Acids; Cysteine; Cystine; Homocysteine; Methionine; Serine | 1962 |
OROTIC ACID AND METABOLISM OF ONE CARBON UNIT: CONVERSION OF FOLIC ACID TO CITROVORUM FACTOR AND METHIONINE SYNTHESIS IN CHICK LIVER.
Topics: Animals; Carbon; Chickens; Folic Acid; Homocysteine; Leuconostoc; Leucovorin; Liver; Metabolism; Methionine; Orotic Acid; Poultry; Proteins; Research; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 1963 |
ORGAN AND INTRACELLULAR LOCATION OF THE METHIONINE METHYL GROUP SYNTHESIZING SYSTEM OF THE RAT.
Topics: Adenosine Triphosphate; Brain; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Glucose; Homocysteine; Kidney; Leuconostoc; Liver; Magnesium; Methionine; Muscles; NAD; Pectoralis Muscles; Proteins; Pyridoxal Phosphate; Rats; Research; Serine; Spectrophotometry | 1964 |
REPRESSION BY METHIONINE OF CYSTATHIONASE FORMATION IN ESCHERICHIA COLI.
Topics: Amino Acids; Chloramphenicol; Cystathionine gamma-Lyase; Cysteine; Enzymes; Escherichia coli; Homocysteine; Methionine; Proteins; Pyruvates; Research; Salmonella; Serine | 1964 |
CYSTATHIONINE CLEAVAGE ENZYMES OF NEUROSPORA.
Topics: Amino Acid Oxidoreductases; Amino Acids; Butyrates; Cystathionine; Cysteine; Homocysteine; Iodoacetates; L-Lactate Dehydrogenase; Maleates; Neurospora; Pyridoxal Phosphate; Pyruvates; Research; Serine; Sulfhydryl Compounds | 1964 |
THE INFLUENCE OF ETHIONINE, METHIONINE, CHOLINE, AND RELATED COMPOUNDS ON LIVER GLYCOGEN DEPOSITION IN ADRENALECTOMIZED RATS: RELATION TO THE MODE OF ACTION OF GLUCOCORTICOIDS.
Topics: Adrenalectomy; Choline; Cysteine; Ethionine; Glucocorticoids; Glucose; Homocysteine; Hydrocortisone; Liver; Liver Glycogen; Methionine; Pharmacology; Research; Serine; Tyrosine | 1964 |
The involvement of phosphorylated serine in the conversion of homocysteine to methionine by Streptococcus lactis.
Topics: Butyrates; Homocysteine; Humans; Lactococcus lactis; Lipid Metabolism; Methionine; Phosphorylation; Serine; Streptococcus | 1955 |
Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor.
Topics: Adult; Carbon; Carbon Isotopes; Female; Folic Acid; Homocysteine; Humans; Leucine; Methionine; Methylation; Reference Values; Serine | 2004 |
Folate deprivation reduces homocysteine remethylation in a human intestinal epithelial cell culture model: role of serine in one-carbon donation.
Topics: Amino Acids; Caco-2 Cells; Culture Media; Epithelial Cells; Folic Acid Deficiency; Homocysteine; Humans; Intestinal Mucosa; Intestines; Kinetics; Methionine; Methylation; Serine | 2004 |
Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency.
Topics: Animal Feed; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine beta-Synthase; Cysteine; Female; Heterozygote; Homocysteine; Hyperhomocysteinemia; Lipotropic Agents; Liver; Male; Methionine; Methyltransferases; Mice; Mice, Inbred C57BL; Regression Analysis; Serine | 2004 |
Crystal structure of S-ribosylhomocysteinase (LuxS) in complex with a catalytic 2-ketone intermediate.
Topics: Alanine; Arginine; Bacillus subtilis; Bacterial Proteins; Binding Sites; Carbon-Sulfur Lyases; Catalysis; Cobalt; Crystallization; Crystallography, X-Ray; Cysteine; Ferrous Compounds; Histidine; Homocysteine; Hydrolases; Ketones; Models, Molecular; Mutagenesis, Site-Directed; Serine; Spectrophotometry, Ultraviolet; Substrate Specificity; Vibrio | 2005 |
Dietary vitamin B-6 restriction does not alter rates of homocysteine remethylation or synthesis in healthy young women and men.
Topics: Adult; Carbon Isotopes; Deuterium; Female; Glycine; Homocysteine; Humans; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pyridoxal Phosphate; Serine; Vitamin B 6 | 2005 |
Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women.
Topics: Adult; Amino Acids; Female; Folic Acid; Folic Acid Deficiency; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Leucine; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Serine | 2005 |
Automated assay for the determination of methylmalonic acid, total homocysteine, and related amino acids in human serum or plasma by means of methylchloroformate derivatization and gas chromatography-mass spectrometry.
Topics: Amino Acids; Autoanalysis; Formates; Gas Chromatography-Mass Spectrometry; Glycine; Homocysteine; Humans; Indicators and Reagents; Methionine; Methylmalonic Acid; Plasma; Reference Values; Sensitivity and Specificity; Serine; Serum | 2005 |
Relation of plasma glycine, serine, and homocysteine levels to schizophrenia symptoms and medication type.
Topics: Adult; Amino Acids; Antipsychotic Agents; Clozapine; Female; Glycine; Homocysteine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Serine | 2005 |
Evaluation of a new enzymatic method for homocysteine measurement.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Cystathionine beta-Synthase; Female; Homocysteine; Humans; Immunoenzyme Techniques; L-Lactate Dehydrogenase; Male; Middle Aged; NAD; Serine; Spectrophotometry | 2006 |
Screening of toxicity biomarkers for methionine excess in rats.
Topics: Amino Acids; Analysis of Variance; Animals; Bilirubin; Biomarkers; Cystathionine; Diet; Gas Chromatography-Mass Spectrometry; Glycine; Hemolysis; Homocysteine; Iron; Male; Methionine; Rats; Rats, Inbred F344; Serine; Spleen | 2006 |
Conversion of methionine to cysteine in Bacillus subtilis and its regulation.
Topics: Bacillus subtilis; Bacterial Proteins; Carbon-Oxygen Lyases; Cystathionine; Cystathionine beta-Synthase; Cysteine; Gene Expression Regulation, Bacterial; Genes, Bacterial; Homocysteine; Lyases; Methionine; Operon; Promoter Regions, Genetic; Serine; Substrate Specificity | 2007 |
Homocysteine induces tau hyperphosphorylation in rats.
Topics: Alzheimer Disease; Animals; Binding Sites; Brain; Brain Chemistry; Homocysteine; Hyperhomocysteinemia; Injections, Intraventricular; Male; Neurofibrillary Tangles; Phosphorylation; Protein Phosphatase 2; Rats; Rats, Wistar; Serine; tau Proteins; Time Factors | 2007 |
High-casein diet suppresses guanidinoacetic acid-induced hyperhomocysteinemia and potentiates the hypohomocysteinemic effect of serine in rats.
Topics: Animals; Caseins; Cysteine; Diet; Glycine; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats; Rats, Wistar; Serine | 2008 |
Human polycomb 2 protein is a SUMO E3 ligase and alleviates substrate-induced inhibition of cystathionine beta-synthase sumoylation.
Topics: Cystathionine beta-Synthase; Cysteine; Enzyme Activation; Homocysteine; Humans; Ligases; Models, Molecular; Polycomb-Group Proteins; Protein Processing, Post-Translational; Repressor Proteins; S-Adenosylmethionine; Serine; SUMO-1 Protein; Ubiquitin-Protein Ligases | 2008 |
High casein diet decreases plasma homocysteine concentration in rats.
Topics: Amino Acids; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Cystathionine beta-Synthase; Diet; Dose-Response Relationship, Drug; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats; Rats, Wistar; Serine | 2009 |
Hepatic cystathionine beta-synthase activity does not increase in response to methionine supplementation in rats fed a low casein diet: association with plasma homocysteine concentrations.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Caseins; Cystathionine beta-Synthase; Cysteine; Dietary Proteins; Dietary Supplements; Dose-Response Relationship, Drug; Energy Intake; Glycine; Homocysteine; Liver; Male; Methionine; Organ Size; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Weight Gain | 2009 |
Mutagenesis studies of human cystathionine beta-synthase: residues important for heme binding and substrate interactions.
Topics: Catalytic Domain; Cystathionine beta-Synthase; Heme; Homocysteine; Humans; Hydrogen Sulfide; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Serine; Spectrophotometry; Structure-Activity Relationship | 2010 |
Diet-induced hyperhomocysteinemia increases amyloid-beta formation and deposition in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Brain; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Down-Regulation; Female; Food, Formulated; Glycogen Synthase Kinase 3; Homocysteine; Hyperhomocysteinemia; Mice; Mice, Transgenic; Plaque, Amyloid; Serine | 2010 |
Effects of gamma-ray-induced free radicals on the metal content and amino acid composition of human metallothionein-1.
Topics: Butyrates; Cystathionine; Cysteine; Gamma Rays; Homocysteine; Humans; Metallothionein; Methionine; Serine; Zinc | 2011 |
Factors contributing to the resistivity of a higher casein diet against choline deficiency-induced hyperhomocysteinemia in rats.
Topics: Animals; Caseins; Choline; Choline Deficiency; Diet; Glycine; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats; Rats, Wistar; Serine | 2012 |
Detection of reaction intermediates during human cystathionine β-synthase-monitored turnover and H2S production.
Topics: Cystathionine beta-Synthase; Cysteine; Heme; Homocysteine; Humans; Hydrogen Sulfide; Kinetics; Serine | 2012 |
Traceless chemical ligation from S-, O-, and N-acyl isopeptides.
Topics: Acylation; Biochemistry; Cysteine; Homocysteine; Peptides; Peptides, Cyclic; Serine; Solid-Phase Synthesis Techniques; Tryptophan; Tyrosine | 2014 |
L-serine supplementation attenuates alcoholic fatty liver by enhancing homocysteine metabolism in mice and rats.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Dietary Supplements; Energy Intake; Ethanol; Fatty Liver, Alcoholic; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Rats; Rats, Wistar; S-Adenosylmethionine; Serine; Triglycerides | 2015 |
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Chickens; Choline; Cystathionine gamma-Lyase; Cysteine; Dietary Proteins; Folic Acid; Glycine; Homocysteine; Liver; Male; Meat; Methionine; Rats; Rats, Wistar; Riboflavin; RNA, Messenger; Sarcosine; Serine; Vitamin B 12; Vitamin B 6 | 2015 |
Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users.
Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Carbon; Contraceptives, Oral; Cystathionine; Dietary Supplements; Female; Glycine; Homocysteine; Humans; Kynurenine; Leucine; Methionine; Methylamines; Multivariate Analysis; Pyridoxal Phosphate; Pyridoxine; Serine; Tryptophan; Vitamin B 6 Deficiency; Young Adult | 2015 |
Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Cell Line, Tumor; Colorectal Neoplasms; DNA Methylation; Homocysteine; Humans; Methionine; Neoplasms; RNA; S-Adenosylmethionine; Serine; Stress, Physiological | 2016 |
Inhibition of homocysteine-induced endoplasmic reticulum stress and endothelial cell damage by l-serine and glycine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Apoptosis; Cell Line; Cell Survival; Cystathionine beta-Synthase; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Endothelial Cells; Glycine; Glycine Hydroxymethyltransferase; Heat-Shock Proteins; Homocysteine; Humans; RNA Interference; RNA, Small Interfering; Serine; Transcription Factor CHOP; X-Box Binding Protein 1 | 2016 |
Homocysteine ameliorates the endothelium-independent hypoxic vasoconstriction via the suppression of phosphatidylinositol 3-kinase/Akt pathway in porcine coronary arteries.
Topics: Animals; Blotting, Western; Class Ia Phosphatidylinositol 3-Kinase; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Homocysteine; Hypoxia; In Vitro Techniques; Myosin Light Chains; Phosphorylation; Protein Subunits; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Swine; Time Factors; Tyrosine; Vasoconstriction | 2017 |
Serine alleviates oxidative stress via supporting glutathione synthesis and methionine cycle in mice.
Topics: Animals; Antioxidants; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cycloleucine; Cystathionine beta-Synthase; Defoliants, Chemical; Dietary Supplements; Diquat; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glutathione; Hepatocytes; Homocysteine; Male; Methionine; Methionine Adenosyltransferase; Mice, Inbred C57BL; Oxidative Stress; Random Allocation; RNA Interference; Serine; Specific Pathogen-Free Organisms | 2017 |
Biogenesis of Hydrogen Sulfide and Thioethers by Cystathionine Beta-Synthase.
Topics: Alanine; Animals; Biomarkers; Catalysis; Cystathionine beta-Synthase; Cysteine; Haplorhini; Homocysteine; Hydrogen Sulfide; Kinetics; Mice; Mice, Knockout; Serine; Sulfides; Sulfur | 2018 |
Identification and characterization of Helicobacter pylori O-acetylserine-dependent cystathionine β-synthase, a distinct member of the PLP-II family.
Topics: Bacterial Proteins; Binding Sites; Catalytic Domain; Cystathionine; Cystathionine beta-Synthase; Enzyme Stability; Helicobacter pylori; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methionine; Serine; Substrate Specificity | 2019 |
Crystal structures and snapshots along the reaction pathway of human phosphoserine phosphatase.
Topics: Binding Sites; Crystallization; Crystallography, X-Ray; Escherichia coli; Homocysteine; Humans; Ligands; Molecular Dynamics Simulation; Phosphoric Monoester Hydrolases; Phosphoserine; Protein Interaction Domains and Motifs; Serine | 2019 |
Putative Nox2 inhibitors worsen homocysteine-induced impaired acetylcholine-mediated relaxation.
Topics: Acetophenones; Acetylcholine; Animals; Aorta; Enzyme Inhibitors; Glycoproteins; Homocysteine; In Vitro Techniques; Male; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; Nitric Oxide Synthase Type III; Phosphorylation; Rabbits; Serine; Threonine; Vasodilation; Vasodilator Agents | 2019 |
Cystathionine β-synthase is involved in cysteine biosynthesis and H
Topics: Biocatalysis; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; DNA, Complementary; Genes, Protozoan; Heme; Homocysteine; Hydrogen Sulfide; Kinetics; Serine; Toxoplasma | 2020 |
Catalytic specificity of the Lactobacillus plantarum cystathionine γ-lyase presumed by the crystallographic analysis.
Topics: Catalysis; Crystallography, X-Ray; Cystathionine; Cystathionine gamma-Lyase; Homocysteine; Lactobacillus plantarum; Serine; Substrate Specificity | 2020 |
Discrimination of blood metabolomics profiles in neonates with idiopathic polyhydramnios.
Topics: Alanine; Asparagine; Aspartic Acid; Cesarean Section; Child; Chromatography, Liquid; Female; Glutamates; Homocysteine; Humans; Infant, Newborn; Phenylalanine; Polyhydramnios; Pregnancy; RNA, Transfer; Serine; Tandem Mass Spectrometry | 2023 |