homocysteine has been researched along with s-adenosylmethionine in 463 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 169 (36.50) | 18.7374 |
| 1990's | 39 (8.42) | 18.2507 |
| 2000's | 138 (29.81) | 29.6817 |
| 2010's | 93 (20.09) | 24.3611 |
| 2020's | 24 (5.18) | 2.80 |
| Authors | Studies |
|---|---|
| Campbell, CD; Ficicioglu, C; Ganesh, J | 1 |
| Aydin, A; Cansever, S; Kiykim, E; Soyucen, E; Yalcinkaya, C; Zeybek, CA; Zubarioglu, T | 1 |
| Chen, LQ; Chen, RY; Chen, XQ; Li, XZ; Lin, Q; Shen, YY; Wu, HY; Xu, QY; Zhu, XM; Zhu, Y | 1 |
| Butt, VS; Poulton, JE | 1 |
| Barailler, J; Cronenberger, L; Fonlupt, P; Pacheco, H; Roche, M | 1 |
| Kuchino, Y; Nishimura, S; Yasuda, T | 1 |
| Duncan, GS; Wolberg, G; Zimmerman, TP | 1 |
| Kass, L; Peters, CL; Toler, LA | 1 |
| Furuichi, Y | 1 |
| Mertens, PP; Payne, CC | 2 |
| Benesh, FC; Carl, GF | 1 |
| Cornatzer, WE; Duerre, JA; Hoffman, DR | 1 |
| Johnston, JM; Kredich, NM | 1 |
| Chrin, LR; Jaffe, JJ | 1 |
| Deeprose, RD; Duncan, GS; Harvey, RJ; Wolberg, G; Zimmerman, TP | 1 |
| Mitsuda, H; Nadamoto, T; Nakajima, K | 1 |
| Eloranta, TO | 1 |
| Borchardt, RT; Wu, BS; Wu, YS | 3 |
| Farrugia, G; Lederer, E; Legreverend, M; Michelot, R | 1 |
| Cantoni, GL; Chiang, PK; Richards, HH | 1 |
| Kerr, SJ; Trewyn, RW | 1 |
| Legraverend, M; Michelot, R | 1 |
| Borchardt, RT; Huber, JA; Wu, YS | 2 |
| Eloranta, TO; Kajander, EO; Raina, AM | 2 |
| Lin, RL; Narasimhachari, N | 1 |
| Dainko, JL; Schlenk, F | 1 |
| de Robichon-Szulmajster, H; Surdin-Kerjan, Y | 1 |
| Petrotta-Simpson, TF; Spence, KD; Talmadge, JE | 1 |
| Jamaluddin, M; Kim, S; Paik, WK | 1 |
| Halper, LA; Norton, SJ | 1 |
| Borchardt, RT; Wu, YS | 2 |
| Follmann, H; Kuntz, I; Zacharias, W | 1 |
| Hoffman, J | 1 |
| Barbey, R; Henry, D; Surdin-Kerjan, Y; Thomas, D | 1 |
| Miller, JW; Selhub, J | 1 |
| Cherest, H; Surdin-Kerjan, Y; Thomas, D | 1 |
| Balzarini, J; Cools, M; De Clercq, E | 1 |
| Fraher, LJ; McFadden, RG | 1 |
| Borchardt, RT; Cools, M; De Clercq, E; Hasobe, M | 1 |
| Liteplo, RG | 2 |
| Bottiglieri, T; Chanarin, I; Metz, J; Van der Westhuyzen, J; Vieira-Makings, E | 1 |
| Borchardt, RT; Kramer, DL; Porter, CW; Sufrin, JR | 1 |
| Benyon, RC; Church, MK; Holgate, ST | 1 |
| Borchardt, RT; Borcherding, DR; Hasobe, M; Keller, BT; Mckee, JG | 1 |
| Daino, L; Feo, F; Garcea, R; Pascale, R; Puddu, M; Ruggiu, ME; Satta, G; Seddaiu, MA; Sequenza, MJ; Simile, MM | 1 |
| Ellis, M; Frost, P; Judde, JG | 1 |
| Henning, SM; McKee, RW; Swendseid, ME | 1 |
| Hipwell, SE; Liteplo, RG | 1 |
| Gharib, A; Reynaud, D; Sarda, N | 1 |
| Anders, MW; Cooper, AJ; Hollander, MM | 1 |
| Gharib, A; Greenland, T; Hamidi, J; Khatchadourian, C; Menezo, Y; Sarda, N | 1 |
| Borchardt, RT; Cools, M; De Clercq, E; Hasobe, M; Ishii, H; McKee, JG | 1 |
| Borchardt, RT; De Gunzburg, J; Guitton, MC; Keller, BT; Part, D; Véron, M | 1 |
| Allen, PT; Hernandez, L; Lijinsky, W; Poirier, LA | 1 |
| Dyer, JR; Greenwood, CE | 1 |
| Martínez del Pozo, A; Mato, JM; Mérida, I; Pajares, MA; Varela, I; Villalba, M | 1 |
| Pike, MC; Snyderman, R | 2 |
| Carreau, S; Drosdowsky, MA; Kamtchouing, P; Papadopoulos, V | 1 |
| Finkelstein, JD; Harris, BJ; Martin, JJ | 2 |
| Blanchflower, J; Keating, S; Kennedy, DG; Kennedy, S; McPartlin, J; Molloy, A; Rice, D; Scott, JM; Weir, DG | 1 |
| Djurhuus, R; Lillehaug, JR; Male, R; Svardal, AM; Ueland, PM | 1 |
| Aarsaether, N; Aarsland, A; Berge, RK; Svardal, AM; Ueland, PM | 1 |
| Aarsaether, N; Aarsland, A; Berge, RK; Lønning, PE; Refsum, H; Svardal, AM; Ueland, PM | 1 |
| Brasitus, TA; Dudeja, PK; Halline, AG | 1 |
| Lillehaug, JR; Male, R; Refsum, H; Ueland, PM | 1 |
| Chiang, PK; Gordon, RK; Miura, GA; Montgomery, JA | 1 |
| Stipanuk, MH | 2 |
| Hampton, A; Kappler, F; Vrudhula, VM | 1 |
| Duerre, JA; Wallwork, JC | 1 |
| Carrera, CJ; Carson, DA; Kajander, EO; Kubota, M; Montgomery, JA | 1 |
| Crooks, PA; Godin, CS | 1 |
| Djurhuus, R; Svardal, A; Ueland, PM | 1 |
| Samet, MK | 1 |
| Refsum, H; Svardal, A; Ueland, PM | 1 |
| Loo, G; Smith, JT | 1 |
| Fonlupt, P; Gharib, A; Pacheco, H; Rey, C; Sarda, N | 1 |
| Cantoni, GL | 1 |
| Gill, MW; Schatz, RA | 1 |
| Kim, S | 1 |
| Carnegie, PR; Jones, GM | 1 |
| Gawthorne, JM; Smith, RM | 1 |
| Eskin, B; Linn, S | 2 |
| Salvatore, F; Shapiro, SK; Utili, R; Zappia, V | 1 |
| Kerr, SJ | 1 |
| Baxter, CS; Byvoet, P | 2 |
| Nakamura, KD; Schlenk, F | 1 |
| Banerjee, AK; Moyer, SA; Rhodes, DP | 1 |
| Kutzbach, C; Stokstad, EL | 1 |
| Inukai, S; Sato, K; Shimizu, S | 1 |
| Hanna, ML; Hutton, JJ; Taylor, RT | 1 |
| Cello, JP; Finkelstein, JD; Kyle, WE | 1 |
| Bussolotti, DL; Chang, CD; Coward, JK | 1 |
| Geller, I | 1 |
| Domino, EF; Krause, RR | 1 |
| Murphy, JT; Spence, KD | 1 |
| Chou, TC; Talalay, P | 1 |
| Flavin, M; Savin, MA; Slaughter, C | 1 |
| Lautenberger, JA; Linn, S | 1 |
| Balish, E | 2 |
| Antoniewski, J; Cherest, H; de Robichon-Szulmajster, H; Surdin-Kerjan, Y | 1 |
| Greene, RC; Kung, HF; Spears, C; Weissbach, H; Williams, RD | 1 |
| Ferro, AJ; Spence, KD | 1 |
| Jaenicke, L; Rüdiger, H | 1 |
| Cartenì-Farina, M; Galletti, P; Servillo, L; Zappia, V | 1 |
| Coulter, AW; Lombardini, JB; Talalay, P | 1 |
| Ariga, N; Hatanaka, H; Katsuki, H; Nagai, J | 1 |
| Grabski, J; Paszewski, A | 1 |
| Hutson, NK; Shapiro, SK; Spence, KD | 1 |
| Hildesheim, J; Hildesheim, R; Lederer, E | 1 |
| Jungermann, K; Wood, NP | 1 |
| Boucher, Y; Lachance, RA; Paquin, R | 1 |
| Hill, LJ; Martin, WG | 1 |
| Himwich, HE; Lin, RL; Narasimhachari, N | 1 |
| Pendleton, RG; Snow, IB | 1 |
| Finkelstein, JD; Harris, B | 1 |
| Taylor, RT; Weissbach, H | 1 |
| Mangum, JH; North, JA; Steuart, BW | 1 |
| Draper, MW; Mangum, JH; North, JA | 1 |
| Killick, KA | 1 |
| Mangum, JH; North, JA | 1 |
| Brodie, JD; Burke, GT; Mangum, JH | 1 |
| Chen, SS; Duerre, JA; Walgate, JH | 1 |
| Spence, KD | 1 |
| Barchas, J; Deguchi, T | 1 |
| Demain, AL; White, RF | 1 |
| Hill, MW; Mann, SP | 1 |
| Fuller, RW; Hemrick-Leucke, SK; Perry, KW | 1 |
| Glazer, RI; Hartman, KD | 1 |
| Chiang, PK; Morita, Y; Siraganian, RP | 1 |
| Morita, Y; Siraganian, RP | 1 |
| Ahl, R | 1 |
| Baglioni, C; de Ferra, F | 1 |
| Dev, VG; Mixon, JC | 1 |
| Biot, N; Fonlupt, P; Macovschi, O; Pacheco, H; Pacheco, Y; Perrin-Fayolle, M | 1 |
| Hoffman, RM | 1 |
| Cornatzer, WE; Haning, JA; Hoffman, DR | 2 |
| Coalson, DW; Hoffman, RM; Mecham, JO; Stern, PH | 1 |
| Tudball, N | 1 |
| Hattori, H; Kanfer, JN | 1 |
| Cooper, AJ | 1 |
| Hyman, C; Lever, OW; White, HL | 1 |
| Hoffman, RM; Stern, PH | 1 |
| Porta, R; Schatz, RA; Sellinger, OZ; Wilens, TE | 1 |
| Barber, JR; Clarke, S | 1 |
| Helland, S; Ueland, PM | 2 |
| Hilton, MA; Hoffman, JL; Sparks, MK | 1 |
| Jaiswal, RK; Landon, EJ; Sastry, BV | 1 |
| Hoffman, RM; Stern, PH; Wallace, CD | 1 |
| Finkelstein, JD; Martin, JJ | 1 |
| Poirier, LA; Shivapurkar, N | 1 |
| Bloch, CA; German, DC; Kredich, NM | 1 |
| Hershfield, MS; Kredich, NM | 1 |
| Chabannes, B; Cronenberger, L; Gharib, A; Pacheco, H; Sarda, N | 1 |
| Finkelstein, JD; Harris, BJ; Kyle, WE; Martin, JJ | 1 |
| Schatz, RA; Sellinger, OZ; Wilens, TE | 2 |
| Gupta, KC; Roy, P | 1 |
| Fonlupt, P; Pacheco, H; Rey, C | 1 |
| Della Ragione, F; Galletti, P; Manna, C; Porcelli, M; Romeo, G | 1 |
| Arrang, JM; Bidart, JM; Bohuon, C; Christa, L | 1 |
| Cornatzer, WE; Duerre, JA; Hoffman, DR; Marion, DW | 1 |
| Branno, M | 1 |
| McGee, R; Rabe, CS; Williams, TP | 1 |
| Alonso-Aperte, E; Alvarez, L; Caballería, J; Deulofeu, R; Gassó, M; Mato, JM; Rodés, J; Rubio, M; Varela-Moreiras, G | 1 |
| Buc-Calderon, P; Tinton, S | 1 |
| Boers, GH; de Franchis, R; Fowler, B; Graham, I; Kozich, V; Kraus, E; Kraus, JP | 1 |
| Blom, HJ; Copius Peereboom-Stegeman, JH; Deabreu, RA; Eskes, TK; Noordhoek, J; Trijbels, FJ; Vanaerts, LA | 1 |
| De Santo, NG; Galletti, P; Ingrosso, D; Perna, AF; Zappia, V | 1 |
| Bukovska, G; Kery, V; Kraus, JP | 1 |
| Croteau, S; Menezo, Y | 1 |
| García-Cuevas, M; Pérez-Olleros, L; Ruiz-Roso, B; Varela-Moreiras, G | 1 |
| Miller, JW; Nadeau, MR; Selhub, J; Smith, D; Smith, J | 1 |
| Drummond, JT; Matthews, RG | 1 |
| Miller, JW; Nadeau, MR; Selhub, J; Smith, D | 1 |
| Christensen, B; Ueland, PM | 1 |
| Blumenthal, RM; Drummond, JT; Huang, S; Matthews, RG | 1 |
| Balińska, M; Natorff, R; Paszewski, A | 1 |
| Allen, RH; Chandler, CJ; Halsted, CH; James, SJ; Muskhelishvili, L; Poirier, L; Stabler, SP; Villanueva, J | 1 |
| Angst, CP; Fowler, B; Haefeli, WE; Jordan, PP; Loehrer, FM; Ritz, R | 1 |
| Blom, HJ; Bökkerink, JP; De Abreu, RA; Keuzenkamp-Jansen, CW; Trijbels, JM | 1 |
| Angst, CP; Browne, G; Fowler, B; Frick, G; Haefeli, WE; Loehrer, FM | 1 |
| Aarbakke, J; Endresen, PC; Kildalsen, H; Loennechen, T | 1 |
| Joseph, JA; Miller, JW; Nadeau, MR; Selhub, J; Shukitt-Hale, B; Villalobos-Molina, R | 1 |
| Goulding, CW; Matthews, RG; Postigo, D | 1 |
| Angst, CP; Fowler, B; Haefeli, WE; Loehrer, FM; Schwab, R | 1 |
| Aletta, JM; Cimato, TR; Ettinger, MJ; Zhou, X | 1 |
| Brunone, M; De Santo, NG; Galletti, P; Ingrosso, D; Perna, AF; Zappia, V | 1 |
| Angst, CP; Brunner, FP; Fowler, B; Haefeli, WE; Loehrer, FM | 1 |
| Finkelstein, JD | 3 |
| Banerjee, R; Chen, Z | 1 |
| Bottiglieri, T; Charles, HC; Gray, L; Hyland, K; Jaeken, J; Kahler, SG; Lazeyras, F; Van Hove, JL; Zeisel, SH | 1 |
| Allman-Farinelli, MA; Jacob, RA; Jenden, DJ; Swendseid, ME | 1 |
| Banerjee, R; Kabil, O | 1 |
| James, SJ; Melnyk, S; Pogribna, M; Pogribny, IP; Yi, P | 1 |
| Dudman, NP; Fu, W; Perry, MA; Wang, XL; Young, K | 1 |
| Bottiglieri, T; Carney, MW; Crellin, R; Laundy, M; Reynolds, EH; Toone, BK | 1 |
| McCarty, MF | 1 |
| Bailey, LB; Cerda, JJ; Hutson, AD; Kauwell, GP; Rampersaud, GC | 1 |
| Angst, CP; Fowler, B; Haefeli, WE; Jäger, K; Litynski, P; Loehrer, FM; Tschöpl, M | 1 |
| Goto, K; Ichioka, K; Iwama, T; Mizuno, Y; Yamagata, S | 1 |
| Blache, D; Durand, P; Loreau, N; Lussier-Cacan, S; Prost, M | 1 |
| Chango, A; James, SJ; Melnyk, S; Pogribna, M; Pogribny, I; Yi, P | 1 |
| Arning, E; Bottiglieri, T; Dayal, S; Faraci, FM; Heistad, DD; Lentz, SR; Maeda, N; Malinow, MR; Sigmund, CD | 1 |
| Delongchamp, RR; Poirier, LA; Sinha, R; Wise, CK | 1 |
| Ashihara, H; Crozier, A; Kato, A; Koshiishi, C; Yama, S | 1 |
| Fowler, B; Hauptmann, B; Kuhn, W; Müller, T; Woitalla, D | 1 |
| Amores-Sánchez, MI; Medina, M; Urdiales, JL | 1 |
| Bassler, BL; Schauder, S; Shokat, K; Surette, MG | 1 |
| Brown, AT; Cruz, C; Drouilhet, J; Eidt, J; Moursi, MM; Mukunyadzi, P; Poirier, LA; Southern, F; Wang, YF; Williams, DK | 1 |
| Brown, AT; Delongchamp, RR; Fink, LM; Fonseca, VA; Poirier, LA; Randolph, CJ; Wise, CK | 1 |
| Fischer, JA; McCann, MP; Snetselaar, KM | 1 |
| Goodman, JE; Helzlsouer, KJ; Lavigne, JA; Selhub, J; Strickland, PT; Wu, K; Yager, JD | 1 |
| Varela-Moreiras, G | 1 |
| Kettunen, H; Peuranen, S; Remus, JC; Saarinen, MT; Tiihonen, K | 1 |
| Capdevila, A; Kerins, DM; Koury, MJ; Rana, S; Wagner, C | 1 |
| Bottiglieri, T; Di Rocco, A; Geraci, A; Godbold, J; Morgello, S; Simpson, D; Werner, P | 1 |
| Delabar, U; Kloor, D; Luippold, G; Mühlbauer, B; Osswald, H | 1 |
| Allen, RH; Gaustadnes, M; Ingerslev, J; Janosík, M; Kery, V; Kozich, V; Kraus, E; Kraus, JP; Maclean, KN; Oliveriusová, J; Rüdiger, N; Skovby, F; Stabler, SP | 1 |
| Desouza, C; Dicker-Brown, A; Fonseca, V; Keebler, M; McNamara, DB; Murthy, SN; Poirier, LA | 1 |
| Christopher, SA; James, SJ; Kruger, WD; Melnyk, S | 1 |
| Arima, K; Asada, T; Eto, K; Kimura, H; Makifuchi, T | 1 |
| Chiang, EP; Herbig, K; Hills, J; Lee, LR; Shane, B; Stover, PJ | 1 |
| Bagley, PJ; Choi, SW; Choumenkovitch, SF; Maeda, N; Nadeau, MR; Selhub, J; Smith, DE | 1 |
| Alonso-Aperte, E; Ubeda, N; Varela-Moreiras, G | 1 |
| Junker, E; Lauterburg, BH; Russmann, S | 1 |
| Borchardt, RT; Ewing, GJ; Miles, RW; Nielsen, LP; Robins, MJ; Yin, D | 1 |
| Ho, PI; Ortiz, D; Rogers, E; Shea, TB | 1 |
| Carmel, R; James, SJ; Melnyk, S | 1 |
| Kim, YI; Mason, JB; Reid, S; Shirwadkar, S; Sohn, KJ; Stempak, JM | 1 |
| Mason, JB | 1 |
| Maruyama, Y; Miyazawa, T; Nakagawa, K | 1 |
| Favier, A; Galan, P; Guilland, JC; Hercberg, S; Potier de Courcy, G | 1 |
| Bandarian, V; Ludwig, ML; Matthews, RG | 1 |
| Agellon, LB; Altarejos, JY; Shields, DJ; Vance, DE; Wang, X | 1 |
| Becker, A; Bouter, LM; Dekker, JM; Heine, RJ; Henry, RM; Jakobs, C; Kostense, PJ; Nijpels, G; Smulders, YM; Stehouwer, CD; Teerlink, T; Zweegman, S | 1 |
| Appling, DR; Chan, SY | 1 |
| ALMENAS, A; SHAPIRO, SK; YPHANTIS, DA | 2 |
| BUCHANAN, JM; ROSENTHAL, S; SMITH, LC | 1 |
| ALMENAS, A; SHAPIRO, SK; THOMSON, JF | 1 |
| Nijhout, HF; Reed, MC; Sparks, R; Ulrich, CM | 1 |
| Di Rocco, A; Werner, P | 1 |
| Block, MA; Curien, G; Douce, R; Jabrin, S; Ravanel, S; Rébeillé, F; Rippert, P | 1 |
| Diaz-Arrastia, R; O'Suilleabhain, P | 1 |
| Clarke, S; Vitali, R | 1 |
| de Meer, K; Jakobs, C; Kulik, W; Smith, DE; Stam, F; Stehouwer, CD; ter Wee, PM; van Guldener, C | 1 |
| Garrow, TA; Nieman, KM; Rowling, MJ; Schalinske, KL | 1 |
| Bottiglieri, T; Di Rocco, A; Godbold, J; Liu, M; Scarano, A; Simpson, D; Tagliati, M; Werner, P | 1 |
| Allen, RH; D'Almeida, V; Guerra-Shinohara, EM; Irazusta, SP; Morita, OE; Pagliusi, RA; Peres, S; Sampaio Neto, LF; Stabler, SP | 1 |
| Cohen, BM; Damico, KE; Gören, JL; Sarmiento, IA; Stoll, AL | 1 |
| Brosnan, JT; Brosnan, ME; Jacobs, RL; Stead, LM | 1 |
| Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA | 1 |
| Cavallaro, RA; D'Anselmi, F; Fuso, A; Scarpa, S; Seminara, L | 1 |
| Becker, A; Bouter, LM; Dekker, JM; Heine, RJ; Henry, RM; Jakobs, C; Kostense, PJ; Nijpels, G; Smulders, YM; Spijkerman, AM; Stehouwer, CD; Teerlink, T | 1 |
| Allen, R; Boger, R; Doshi, S; Goodfellow, J; Lewis, M; McDowell, I; Moat, S; Newcombe, R; Stabler, S | 1 |
| Chen, AH; Davidson, AG; Innis, SM; James, SJ | 1 |
| Amanlou, M; Dehghani, M; Dehpour, AR; Ebrahimkhani, MR; Farsam, H; Honar, H; Kiani, S; Mirazi, N; Pasalar, P; Payabvash, S; Riazi, K; Sadeghipour, H | 1 |
| Fowler, B; Herrmann, W; Kuhlmann, MK; Makowski, J; Obeid, R; Schorr, H | 1 |
| Andrews, LG; Liu, L; Tollefsbol, TO; Ulrey, CL | 1 |
| Bücheler, R; Delabar, U; Fux, R; Gleiter, CH; Grenz, A; Hermes, M; Igel, S; Kloor, D; Mörike, K; Osswald, H; Proksch, B; Röck, T | 1 |
| Beulens, JW; Hendriks, HF; Jakobs, C; Kok, FJ; Schaafsma, G; Sierksma, A; Struys, EA | 1 |
| Allegrucci, C; Denning, C; Lucas, E; Priddle, H; Sinclair, K; Singh, R; Steele, W; Young, L | 1 |
| Artillo, R; Carreras, O; Murillo, ML; Murillo-Fuentes, ML; Ubeda, N; Varela-Moreiras, G | 1 |
| Bermejo, E; Castro, M; Desviat, LR; Leal, F; Mansilla, E; Martínez-Fernández, ML; Martínez-Frías, ML; Pérez, B; Prieto, D; Rodríguez, L; Rodríguez-Pinilla, E; Ugarte, M | 1 |
| Toohey, JI | 1 |
| Davis, CD; Ross, SA; Uthus, EO | 1 |
| Brosnan, JT; Brosnan, ME | 1 |
| Maloney, CA; Rees, WD; Wilson, FA | 1 |
| Fernstrom, JD; Mudd, SH | 1 |
| Blacquiere, KD; Coykendall, CE; Hay, CM; Honsey, LE; Miller, RR; Striegnitz, TR | 1 |
| Fukada, S; Kawagishi, H; Morita, T; Sekiya, A; Sugiyama, K | 1 |
| Shea, TB | 1 |
| Tchantchou, F | 1 |
| Boynton, A; Gregory, JF; James, SJ; Neuhouser, ML; Nijhout, HF; Reed, MC; Shane, B; Ulrich, CM | 1 |
| Hermes, M; Kloor, D; Osswald, H | 1 |
| Burrin, DG; Stoll, B | 1 |
| Chen, D; Fang, M; Yang, CS | 1 |
| Morita, T; Okawa, H; Sugiyama, K | 1 |
| Schalinske, KL; Williams, KT | 1 |
| Clarke, SG; Vinci, CR | 1 |
| Hayakawa, T; Isa, Y; Mishima, T; Tsuge, H | 1 |
| Colombatto, S; Grillo, MA | 1 |
| Blom, HJ; Boers, GH; Heil, SG; Riksen, NP; Smulders, Y | 1 |
| Bottiglieri, T; Cross, JC; Elmore, CL; Gravel, RA; Krupenko, NI; Krupenko, SA; Leclerc, D; Matthews, RG; Rozen, R; Watson, ED; Wu, X | 1 |
| Alonso-Aperte, E; González, MP; Póo-Prieto, R; Varela-Moreiras, G | 1 |
| Benevenga, NJ | 1 |
| Achón, M; Alonso-Aperte, E; Ubeda, N; Varela-Moreiras, G | 1 |
| Cillessen, SA; Giroth, CP; Jakobs, C; Krijnen, PA; Meischl, C; Muller, A; Musters, RJ; Niessen, HW; Rauwerda, JA; Roos, D; Sipkens, JA; Smith, DE; Smulders, YM; Spreeuwenberg, MD; Stehouwer, CD; van Hinsbergh, VW | 1 |
| Chen, J; Matharu, KS; Perry, C; Stover, PJ; Yu, S | 1 |
| Reeves, PG; Saari, JT; Uthus, EO | 1 |
| Allen, RH; Barbosa, PR; Braga, RC; Guerra-Shinohara, EM; Hirata, MH; Hirata, RD; Machado, AL; Sampaio-Neto, LF; Stabler, SP | 1 |
| Banerjee, R; Dayal, S; Lentz, SR; Prudova, A; Stabler, S; Vitvitsky, V | 1 |
| Herrmann, W; Obeid, R | 2 |
| Jianzhong, Z; Jinge, Z; Juan, S; Shenglan, W; Shuren, W; Xiaoqun, H; Yideng, J; Ying, H | 1 |
| Chan, C; Ji, C; Kaplowitz, N; Kuhlenkamp, J; Shinohara, M | 1 |
| Alberto, JM; Audonnet-Blaise, S; Blaise, SA; Daval, JL; Guéant, JL | 1 |
| Cavallaro, RA; Confaloni, A; D'Anselmi, F; Fuso, A; Piscopo, P; Scarpa, S; Zampelli, A | 1 |
| Becker, A; Bode, U; Jaehde, U; Linnebank, M; Pels, H; Schlegel, U; Vezmar, S | 1 |
| Chen, YJ; Chen, YM; Chiang, EP; Hsiao, M; Huang, SF; Hwang, SF; Lee, YH; Li, AF; Li, YS; Liu, SP; Tsai, TF | 1 |
| Bouter, LM; Dekker, JM; Heine, RJ; Jakobs, C; Nijpels, G; Polak, BC; Stehouwer, CD; Stolk, RP; Teerlink, T; Van Hecke, MV | 1 |
| Miller, RR; Walcher, BN | 1 |
| Antelava, NA; Gogoluari, LI; Gogoluari, MI; Okudzhava, MV; Pirtskhalaĭshvili, NN | 1 |
| Guizhong, L; Jiantuan, X; Jun, C; Shuren, W; Yideng, J; Zhihong, L | 1 |
| Allen, RH; Barbosa, PR; Carvalho, FR; Guerra-Shinohara, EM; Hirata, MH; Hirata, RD; Luchessi, AD; Stabler, SP; Trentin, R | 1 |
| Castro, CC; Garrow, TA; Koutmos, M; Szegedi, SS | 1 |
| Eckert, R; Geisel, J; Herrmann, W; Hübner, U; Schorr, H | 1 |
| Alsaraby, A; Chan, AY; Shea, TB | 1 |
| Breaker, RR; Lee, ER; Lim, J; Morales, DR; Wang, JX | 1 |
| Martínez-Frías, ML | 1 |
| Adams, ZF; Cole, NW; Miller, RR; Walcher, BN; Weaver, KR | 1 |
| Coppin, JF; Qu, W; Waalkes, MP | 1 |
| Anderstam, B; Axelsson, J; Bárány, P; Carrero, JJ; Garibotto, G; Lindholm, B; Qureshi, AR; Stenvinkel, P; Suliman, ME; Valli, A | 1 |
| Han, T; James, SR; Karpf, AR; Melnyk, S; Pogribny, IP; Tryndyak, VP | 1 |
| Allen, RH; Carvalho, FR; Guerra-Shinohara, EM; Hirata, MH; Hirata, RD; Lopreato, FR; Robi, DL; Sampaio-Neto, LF; Stabler, SP | 1 |
| Blom, H; Linnebank, M; Moskau, S; Semmler, A; Smith, D; Smulders, Y; Struys, E | 1 |
| Bunout, D; de la Maza, MP; Hirsch, S; Leiva, L; Llanos, M; Montequin, MJ; Pinardi, G; Ronco, AM | 1 |
| Kraus, JP; Kruger, WD; Majtan, T; Singh, LR; Wang, L | 1 |
| Miller, AL | 1 |
| Garcia, P; Herrmann, M; Herrmann, W; Hübner, U; Ross, S; Schorr, H; Taban-Shomal, O; Umanskaya, N; Wagner, A; Wildemann, B; Wolny, M | 1 |
| Garcia, P; Herrmann, M; Herrmann, W; Hübner, U; Ross, S; Schorr, H; Taban-Shomal, O; Tami, A; Umanskaya, N; Wagner, A; Wildemann, B; Wolny, M | 1 |
| Chen, WW; Chiang, EP; Tang, FY; Wang, YC | 1 |
| Agrawal, N; Banerjee, R | 1 |
| Kharbanda, KK | 1 |
| Bauer, BA; Cha, SS; Loehrer, LL; Mandrekar, JN; Sood, A; Thompson, MA; Wahner-Roedler, DL | 1 |
| Mori, M; Morita, T; Ohuchi, S; Sugiyama, K | 1 |
| Nielsen, FH | 1 |
| Chambers, ST; Elmslie, JL; Fink, JN; George, PM; Lever, M; Richards, AM; Scott, RS; Slow, S | 1 |
| Cvetanovska, G; Frommann, I; Jessen, F; Kölsch, H; Kornhuber, J; Lewczuk, P; Linnebank, M; Maier, W; Popp, J; Smulders, Y | 1 |
| Dillmann, U; Fassbender, K; Herrmann, W; Kostopoulos, P; Obeid, R; Schadt, A | 1 |
| Elias, MS; Green, RM; Henkel, AS | 1 |
| de Jonge, R; de Vries, JH; Eijkemans, MJ; Steegers, EA; Steegers-Theunissen, RP; van Driel, LM; van Meurs, JB | 1 |
| Barone, P; De Bonis, ML; Galletti, P; Ingrosso, D; Longo, K; Pellecchia, MT; Russo, A; Salvatore, A; Tedeschi, G; Tessitore, A; Zappia, V | 1 |
| Batra, V; Devasagayam, TP; Sridhar, S | 1 |
| Devlin, AM; Green, TJ; Innis, SM; McMahon, JA; Skeaff, CM; Venn, BJ; Williams, SM | 1 |
| Basten, GP; de Roos, B; Duncan, G; Duthie, SJ; Horgan, G; Pirie, L; Powers, HJ; Reid, M; Rucklidge, G | 1 |
| Capecci, LM; Chen, NC; Durante, W; Gu, Z; Schafer, AI; Wang, H; Yang, F; Yang, XF | 1 |
| Cavallaro, RA; Fuso, A; Nicolia, V; Scarpa, S | 1 |
| Blom, H; Cvetanovska, G; Farkas, M; Jessen, F; Kölsch, H; Kulic, L; Linnebank, M; Popp, J; Semmler, A; Smith, D; Smulders, Y; Stoffel-Wagner, B; Weller, M | 1 |
| Eckert, R; Herrmann, W; Kasoha, M; Kirsch, SH; Obeid, R | 1 |
| Garrow, TA; Gupta, S; Jiracek, J; Kruger, WD; Li, L; Rozen, R; Schalinske, KL; Strakova, J; Williams, KT | 1 |
| Cheng, K; Geoghagen, NS; Holt, TG; Jensen, KK; Jin, L; Luo, MJ; Luo, Q; Malkowitz, L; Ni, W; Quan, S; Waters, MG; Zhang, A; Zhou, HH | 1 |
| Wagner, C | 1 |
| Chen, SY; Chen, YM; Chiang, EP; Tang, FY; Wang, YC | 1 |
| Garcia, P; Herrmann, M; Herrmann, W; Histing, T; Holstein, JH; Klein, M; Kurz, K; Menger, MD; Pohlemann, T; Siebel, T; Splett, C | 1 |
| de Jonge, R; de Vries, JH; Looman, CW; Obermann-Borst, SA; Steegers, EA; Steegers-Theunissen, RP; Vujkovic, M; Wildhagen, MF | 1 |
| Hahn, NE; Krijnen, PA; Meischl, C; Musters, RJ; Niessen, HW; Rauwerda, JA; Sipkens, JA; Smith, DE; Stehouwer, CD; van Hinsbergh, VW; Wassink, M | 1 |
| Dilger, RN; Garrow, TA; Gupta, S; Kruger, WD; Li, L; Strakova, J; Tryon, K | 1 |
| Balasubramaniam, S; Bjursell, MK; Blom, HJ; Brandberg, G; Cayuela, JA; Engvall, ML; Falkenberg, M; Gustafsson, CM; Halldin, M; Jakobs, C; Lesko, N; Lundeberg, J; Smith, D; Struys, E; von Döbeln, U; Wedell, A | 1 |
| Kim, BH; Kim, CH; Kim, SK; Lee, CH; Lee, HS; Lee, KS; Oh, JM; Ryu, CS; Yun, KU | 1 |
| de Jonge, R; Enneman, AW; Heil, SG; Hofman, A; Rivadeneira, F; Stolk, L; Uitterlinden, AG; van der Velde, N; van Meurs, JB; Zillikens, MC | 1 |
| Casson, RI; Dodds, L; Ho, V; King, WD; Massey, TE; Perkins, SL | 1 |
| Alpert, JE; Arning, E; Bottiglieri, T; Fava, M; Mischoulon, D; Papakostas, GI | 1 |
| Arlt, S; Böger, RH; Jahn, H; Jessen, F; Kölsch, H; Linnebank, M; Popp, J; Schwedhelm, E; Smulders, Y | 1 |
| Beurskens, LW; de Jonge, R; Schoonderwaldt, EM; Steegers-Theunissen, RP; Tibboel, D | 1 |
| Blom, HJ; Farkas, M; Jessen, F; Linnebank, M; Popp, J; Semmler, A; Smith, DE; Smulders, YM | 1 |
| Gong, H; Jiang, Y; Shi, Y; Sun, T; Sun, W; Wang, J; Wei, J; Yang, B; Zhang, H | 1 |
| Caudill, M; Jiang, X; Mikael, LG; Pancer, J; Rozen, R; Wu, Q | 1 |
| Cacciapuoti, F | 1 |
| Duncan, TM; Nijhout, HF; Reed, MC | 1 |
| Booher, K; Borrego, SL; Kaiser, P; Lin, DW | 1 |
| Kang, JS; Kim, BH; Kim, SK; Lee, CH; Lee, HS; Lee, JY; Noh, JR; Park, SK; Ryu, CS; Yun, KU | 1 |
| Aleliunas, RE; Bottiglieri, T; Devlin, AM; Glier, MB; Ngai, YF; Sulistyoningrum, DC | 1 |
| Bodis, M; Geisel, J; Herrmann, W; Hübner, U; Kirsch, SH; Klein, C; Kruse, V; Obeid, R | 1 |
| Baurley, J; Crott, JW; Figueiredo, JC; Haile, RW; Levine, AJ | 1 |
| Bloom, L; Desiderio, DM; Gardner, LA; Groover, CJ; Hartzes, A; Levin, MC; Yates, CR; Zucker-Levin, AR | 1 |
| Bigler, L; Blom, H; Linnebank, M; Prost, JC; Semmler, A; Smith, D; Smulders, Y | 1 |
| Cole, D; Cox, SE; da Costa, KA; Dominguez-Salas, P; Dyer, RA; Fulford, AJ; Hennig, BJ; Innis, SM; Moore, SE; Prentice, AM; Waterland, RA; Zeisel, SH | 1 |
| Chrudinová, M; Demianová, Z; Jiráček, J; Kořínek, M; Mládková, J; Selicharová, I | 1 |
| Chen, YM; Chiang, EP; Lin, WL; Lin, YJ; Tang, FY; Wang, YC | 1 |
| Obeid, R | 1 |
| Ahumada, V; Arraztoa, JA; Bustos, V; Dobierzewska, A; España-Perrot, PP; Fernández, XB; Figueroa-Diesel, H; Illanes, SE; Pérez-Sepúlveda, A; Rice, GE | 1 |
| Dekker, JM; Drevon, CA; Elshorbagy, AK; Nijpels, G; Nurk, E; Nygård, O; Refsum, H; Stehouwer, CD; Teerlink, T; Tell, GS; Ueland, PM; Vinknes, KJ; Vollset, SE | 1 |
| da Cunha, SF; de Freitas, EC; Deminice, R; Franco, GS; Jordao, AA; Rosa, FT | 1 |
| Campion, J; Cordero, P; Martinez, JA; Milagro, FI | 1 |
| Gröber, U; Kisters, K; Schmidt, J | 1 |
| Bain, N; Farkas, M; Ineichen, BV; Kallweit, U; Keskitalo, S; Klotz, L; Linnebank, M; Weller, M | 1 |
| Rogers, E; Shea, TB | 1 |
| Berg, JT; Fliser, D; Friedrich, A; Geisel, J; Heine, GH; Hummel, B; Obeid, R; Rogacev, KS; Roth, HJ; Zawada, AM | 1 |
| Alam, S; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Liu, X; Niedzwiecki, MM; Siddique, AB; Slavkovich, V | 1 |
| Agamme, AL; D'Almeida, V; da Silva, VC; Fernandes, L; Guerra Shinohara, EM; Haseyama, EJ; Muniz, MT | 1 |
| Barroso, M; Blom, HJ; Carlson, BA; Castro, R; de Almeida, IT; Florindo, C; Gladyshev, VN; Handy, DE; Hatfield, DL; Kalwa, H; Loscalzo, J; Michel, T; Silva, Z; Turanov, AA | 1 |
| Cao, CJ; Han, XB; Jiang, YD; Tian, J; Wang, J; Wang, YH; Xu, H; Yang, AN; Yang, XL; Zhang, HP | 1 |
| French, SW; Kharbanda, KK; Orlicky, DJ; Osna, NA; Thomes, PG; Todero, SL; Tuma, DJ | 1 |
| Guan, Z; Niu, B; Wang, J; Wang, X; Wang, Z; Xie, Q; Zhang, T; Zhao, X; Zhu, Z | 1 |
| Chae, SW; Park, SW; Song, JJ; Yadav, MK | 1 |
| Cui, W; Liu, J; Sun, X; Xie, X; Zhang, D; Zhu, Y | 1 |
| Comparotto, H; Deminice, R; Jordao, AA | 1 |
| Akyuz, M; Bakan, N; Boyuk, A; Cikman, O; Gumustekin, K; Keles, MS; Taysi, S | 1 |
| Choi, HS; Choi, YJ; Kim, SK; Kwak, HC; Lee, BH; Sim, WC; Yin, HQ | 1 |
| Cavallaro, RA; Desiderio, C; Di Napoli, A; Fuso, A; Gervasoni, J; Giardina, B; Nicolia, V; Persichilli, S; Scarpa, S | 1 |
| Blanco-González, E; Cinti, M; Fernández de la Campa, MR; Iglesias González, T; Montes-Bayón, M | 1 |
| Miller, D; White, RH; Xu, H | 1 |
| Kim, SK; Kim, YM; Kwak, HC; Oh, SJ | 1 |
| Boonla, C; Kloypan, C; Mutirangura, A; Srisa-art, M | 1 |
| Bodis, M; Geisel, J; Herrmann, M; Herrmann, W; Hübner, U; Kirsch, SH; Laufs, U; Pusceddu, I; Wagenpfeil, S; Werner, C | 1 |
| Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Islam, T; Liu, X; Parvez, F; Peters, BA; Shahriar, H; Siddique, AB; Uddin, MN | 1 |
| Bhatia, P; Singh, N | 1 |
| Anilkumar, N; Brandes, RP; Brewer, AC; Burr, S; Caldwell, A; Dew, T; Dong, X; Halket, J; Hughes, RD; Martin, D; Mistry, RK; Murray, TV; Quaglia, A; Sawyer, GJ; Schröder, K; Shah, AM; Sherwood, R | 1 |
| Chiang, EP; Ko, HA; Lin, YJ; Tang, FY; Wang, YC; Wu, MT | 1 |
| Imiolczyk, B; Jaskolski, M; Manszewski, T; Singh, K | 1 |
| Fontecilla-Camps, JC; Martin, L; Nicolet, Y; Pagnier, A; Zeppieri, L | 1 |
| Adams, PD; Labuschagne, CF; Maddocks, OD; Vousden, KH | 1 |
| Cao, J; Guo, X; He, Y; Jiang, Y; Kong, F; Liu, Z; Ma, S; Tian, J; Wang, Y; Xu, H; Yang, A; Yang, X; Zhang, H; Zhang, M | 1 |
| Andrews, AJ; Gupta, S; Kruger, WD; Kuo, YM; Lee, HO; Li, YS; Slifker, MJ; Wang, L | 1 |
| Bertolo, RF; Brunton, JA; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Bertics, SJ; Luchini, ND; White, HM; Zhang, Q | 1 |
| Kornhuber, J; Lewczuk, P; Linnebank, M; Oikonomidi, A; Popp, J; Semmler, A; Smulders, Y | 1 |
| Apostolakos, MJ; Arning, E; Bottiglieri, T; Doolin, KP; Gough, MS; Mack, CM; Mooney, RA; Morgan, MAM; Pietropaoli, AP; Wexler, O | 1 |
| Karas Kuželički, N | 1 |
| Augoustides-Savvopoulou, P; Barić, I; Blom, HJ; Chien, YH; Dobbelaere, D; Grünert, SC; Opladen, T; Petković Ramadža, D; Rakić, B; Staufner, C; Wedell, A | 1 |
| Feng, D; French, SW; Ganesan, M; Kharbanda, KK; Maillacheruvu, PF; Orlicky, DJ; Osna, NA; Tuma, DJ | 1 |
| Ingenbleek, Y | 1 |
| Cao, JC; He, YY; Jia, YX; Jiang, YD; Jiao, Y; Jin, SJ; Lu, GJ; Ma, SC; Tian, J; Wang, YH; Yang, AN; Yang, XL; Yang, XM; Zhang, H; Zhang, HP; Zhang, MH | 1 |
| Ereño-Orbea, J; Giménez-Mascarell, P; Klaudiny, J; Kraus, JP; Majtan, J; Majtan, T; Martínez-Cruz, LA; Oyenarte, I | 1 |
| Cella, PS; da Silva, LECM; Deminice, R; Jordao, AA; Riberio, DF | 1 |
| Awwad, HM; Eskelund, AR; Geisel, J; Obeid, R; Tillmann, S; Treccani, G; Wegener, G | 1 |
| McCully, KS | 1 |
| Chmurzynska, A; Malinowska, AM; Mlodzik, MA; Nowacka-Woszuk, J; Radziejewska, A; Szwengiel, A | 1 |
| Huse, K; Olecka, M; Platzer, M | 1 |
| Ali, MA; Bakir, MB; Kamel, MA; Khalifa, EA; Refaat, R; Salama, MA | 1 |
| Coalson, DW; Douglas Wallace, C; Erbe, RW; Hoffman, RM; Stern, PH | 1 |
| Flitton, M; Knight, HM; Macdonald, IA; Rielly, N; Smith, AD; Warden, D; Warman, R | 1 |
| Deng, J; Dong, H; Shen, Y; Xie, Z; Xiong, L; Zhang, P; Zhao, G | 1 |
| Corrales, F; Franco, L; Guerrero, L; López-Rodas, G; Martí-Andrés, P; Paradela, A; Pérez, S; Rius-Pérez, S; Sastre, J; Taléns-Visconti, R; Torres, L; Torres-Cuevas, I | 1 |
| Bulko, I; Dmytrenko, I; Korda, M; Nechyporuk, V; Pentiuk, L | 1 |
| Bentley, WE; Bhokisham, N; Brown, AD; Culver, JN; Liu, Y; Payne, GF | 1 |
| Bulgakova, PO; Fedoseev, AN; Grachev, SV; Ivanov, AV; Kruglova, MP; Kubatiev, AA; Samokhin, AS; Virus, ED | 1 |
| Kožich, V; Stabler, S | 1 |
| Elango, R | 1 |
| Kane, MA; Li, J; Liu, T; Petri, MA; Stojan, G | 1 |
| Bharadwaj, B; Dhiman, P; Pillai, RR; Premkumar, N; Rajendiran, S; Ranjan, VP; Wilson, AB | 1 |
| Ha, E; Ha, TK; Heo, Y; Hwang, GS; Jung, J; Kim, M; Park, R; Rho, Y; Seo, JH; Seo, YK | 1 |
| Al-Dhabi, NA; Arasu, MV; Arockiaraj, J; C, M; Chatterjee, S; Choi, KC; Karuppiah, K; Natarajan, S; Raj, V; Ramanujam, GM; Ramasamy, M | 1 |
| Kim, R; Nijhout, HF; Reed, MC | 1 |
| Lin, B; Liu, Q; Tao, Y | 1 |
| G, G; Singh, J | 1 |
| Beltrán, LJ; Bulleid, NJ; Johnstone, IL; Page, AP; Tjahjono, E; Winter, AD | 1 |
| Alberti, C; Benoist, JF; de Baulny, HO; Feillet, F; Garcia-Segarra, N; Guilmin-Crépon, S; Haignere, J; Imbard, A; Kaguelidou, F; Kuster, A; Magréault, S; Perronneau, I; Schiff, M; Schlemmer, D; Toumazi, A | 1 |
| Arning, E; Bottiglieri, T; Collado, MC; Demerath, EW; Fields, DA; Isganaitis, E; Lerin, C; Wasek, B | 1 |
| Bah, S; Cisse, K; Coulibaly, B; Dehbi, H; Diakite, B; Diarra, F; Dolo, G; Holl, JL; Hou, L; Joyce, B; Kamate, B; Kassogue, O; Kassogue, Y; Keita, ML; Kim, K; Ly, M; Maiga, M; Murphy, R; Nadifi, S; Sidibe, FM; Sissoko, AS; Sissoko, SB; Teguete, I; Traore, CB; Traore, D; Wang, J | 1 |
| Fang, H; Gong, D; Kang, Q; Tu, X; Xiang, M; Xiao, K; Zhang, D | 1 |
| Bito, T; Ishihara, A; Iwasaki, R; Watanabe, F; Yabuta, Y | 1 |
| Andexer, JN; Cornelissen, NV; Mohr, MKF; Saleem-Batcha, R | 1 |
| Fukuoka, H; Horiguchi, S; Kagawa, Y; Kawabata, T; Kubo, Y; Nishikawa, M; Shoji, K; Tajima, A | 1 |
| Clément, A; Clément, P; Menezo, YJR; Viot, G | 1 |
39 review(s) available for homocysteine and s-adenosylmethionine
| Article | Year |
|---|---|
Methyl biogenesis.
Topics: Folic Acid; Homocysteine; Humans; Leucovorin; Mental Disorders; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Tetrahydrofolates | 1978 |
The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine.
Topics: Amino Acid Metabolism, Inborn Errors; Cystathionine; Homocysteine; Humans; Methionine; Methylation; S-Adenosylmethionine | 1992 |
Formation of highly reactive vinylglyoxylate (2-oxo-3-butenoate) from amino acids with good leaving groups in the gamma-position. Toxicological implications and therapeutic potential.
Topics: Amino Acids; Animals; Canavanine; Fatty Acids, Monounsaturated; Homocysteine; Methionine Sulfoximine; S-Adenosylmethionine | 1989 |
Metabolism of sulfur-containing amino acids.
Topics: Adenosylhomocysteinase; Animals; Carboxy-Lyases; Cysteine; Female; Homocysteine; Humans; Hydrolases; Isoenzymes; Liver; Male; Methionine; Methionine Adenosyltransferase; Methylation; Polyamines; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Taurine; Transaminases | 1986 |
The biosynthesis of methionine.
Topics: Animals; Apoproteins; Bacteria; Catalysis; Chemical Phenomena; Chemistry; Cobamides; Drug Stability; Enzyme Activation; Escherichia coli; Flavins; Homocysteine; Methionine; Methyltransferases; Molecular Weight; Oxidation-Reduction; Plants; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1973 |
Roles of vitamin B 12 and folic acid in methionine synthesis.
Topics: Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Transferases; Vitamin B 12 | 1970 |
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1984 |
Biochemistry of sulfur-containing amino acids.
Topics: Adenosine; Amino Acid Metabolism, Inborn Errors; Animals; Cysteine; Deoxyadenosines; Homocysteine; Humans; Methionine; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; S-Adenosylmethionine; Structure-Activity Relationship; Sulfur; Sulfurtransferases; Thionucleosides; Thiosulfate Sulfurtransferase | 1983 |
The metabolism of homocysteine: pathways and regulation.
Topics: Animals; Homocysteine; Humans; Hydrolysis; Methionine; Methylation; S-Adenosylmethionine | 1998 |
Homocysteine: a history in progress.
Topics: History, 19th Century; History, 20th Century; Homocysteine; Homocystinuria; Humans; Insulin; Methionine; Neural Tube Defects; North America; Research; S-Adenosylmethionine; Workforce | 2000 |
Pathways and regulation of homocysteine metabolism in mammals.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Heme; Homocysteine; Isoenzymes; Kinetics; Mammals; Methionine; Methionine Adenosyltransferase; Organ Specificity; Oxidation-Reduction; Pyridoxal Phosphate; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tetrahydrofolates | 2000 |
Impaired homocysteine metabolism and atherothrombotic disease.
Topics: Age Factors; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Models, Chemical; Risk Factors; S-Adenosylmethionine; Sex Factors | 2001 |
Roles of homocysteine in cell metabolism: old and new functions.
Topics: Cardiovascular Diseases; Cell Physiological Phenomena; Female; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Nervous System Malformations; Pregnancy; Pregnancy Complications; RNA, Transfer, Amino Acyl; S-Adenosylmethionine | 2001 |
Nutritional regulation of homocysteine: effects of drugs.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Drug Interactions; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Methionine; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; S-Adenosylmethionine; Vitamin B 12; Vitamin B 6 | 2001 |
Biomarkers of nutrient exposure and status in one-carbon (methyl) metabolism.
Topics: Biomarkers; Carbon; Diet; DNA Methylation; Folic Acid; Homocysteine; Humans; Methylation; Nutritional Status; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B Complex | 2003 |
[Hyperhomocysteinemia: an independent risk factor or a simple marker of vascular disease?. 1. Basic data].
Topics: Animals; Arteriosclerosis; Biomarkers; Cystathionine beta-Synthase; Folic Acid Deficiency; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Nitric Oxide; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Rats; Risk Factors; S-Adenosylmethionine; Signal Transduction; Thrombophilia; Vascular Diseases; Vasodilation; Vitamin B 6 Deficiency | 2003 |
Methylation demand and homocysteine metabolism.
Topics: Animals; Homocysteine; Humans; Levodopa; Methionine Adenosyltransferase; Methylation; Methyltransferases; Niacin; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylmethionine | 2004 |
The impact of metabolism on DNA methylation.
Topics: Alzheimer Disease; Animals; Arteriosclerosis; DNA Methylation; Folic Acid; Gene Expression Regulation; Glycine N-Methyltransferase; Homocysteine; Humans; Methionine; Methyltransferases; Models, Biological; S-Adenosylmethionine | 2005 |
Vitamin B12 and methionine synthesis: a critical review. Is nature's most beautiful cofactor misunderstood?
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biological Transport; Bone Marrow; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Myelin Sheath; Nerve Tissue; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
The sulfur-containing amino acids: an overview.
Topics: Allosteric Regulation; Amino Acids, Sulfur; Animals; Cysteine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Proteins; S-Adenosylmethionine; Taurine | 2006 |
Sulfur amino acid metabolism in pregnancy: the impact of methionine in the maternal diet.
Topics: Amino Acids, Sulfur; Animals; Choline; Diet; DNA Methylation; Drug Interactions; Endocrine System; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Methylation; Nutritional Requirements; Pregnancy; Proteins; S-Adenosylmethionine | 2006 |
Homocysteine metabolism and various consequences of folate deficiency.
Topics: Apolipoproteins E; Brain; DNA Methylation; Folic Acid Deficiency; Glutathione Transferase; Homocysteine; Humans; Oxidative Stress; S-Adenosylmethionine | 2006 |
Emerging aspects of gut sulfur amino acid metabolism.
Topics: Amino Acids, Sulfur; Biological Availability; Cysteine; DNA Methylation; Gastrointestinal Diseases; Homocysteine; Humans; Intestinal Absorption; Intestinal Mucosa; Methionine; Nutritional Physiological Phenomena; Oxidation-Reduction; S-Adenosylmethionine | 2007 |
S-adenosylmethionine and its products.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Glycine N-Methyltransferase; Homocysteine; Humans; Liver; Methionine Adenosyltransferase; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
The biochemical structure and function of methylenetetrahydrofolate reductase provide the rationale to interpret the epidemiological results on the risk for infants with Down syndrome.
Topics: Cystathionine beta-Synthase; Down Syndrome; Female; Flavin-Adenine Dinucleotide; Flavins; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Risk Factors; S-Adenosylmethionine; Structure-Activity Relationship | 2008 |
The methylation, neurotransmitter, and antioxidant connections between folate and depression.
Topics: Antioxidants; Biopterins; Depression; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Neurotransmitter Agents; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Tetrahydrofolates | 2008 |
Homocysteine and lipids: S-adenosyl methionine as a key intermediate.
Topics: Alcoholism; Dyslipidemias; Fatty Liver; Homeostasis; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; S-Adenosylmethionine | 2009 |
Alcoholic liver disease and methionine metabolism.
Topics: Alcohol Drinking; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Ethanol; Homocysteine; Humans; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 2009 |
Folate-genetics and colorectal neoplasia: what we know and need to know next.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Colorectal Neoplasms; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Meta-Analysis as Topic; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Single Nucleotide; Randomized Controlled Trials as Topic; Risk Factors; S-Adenosylmethionine; Thymidylate Synthase | 2013 |
The metabolic burden of methyl donor deficiency with focus on the betaine homocysteine methyltransferase pathway.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Dietary Supplements; Disease Models, Animal; DNA Methylation; Fasting; Fatty Liver; Folic Acid; Homocysteine; Humans; Liver; Metabolic Networks and Pathways; Methionine; Muscular Diseases; S-Adenosylmethionine | 2013 |
Neuroenhancement with vitamin B12-underestimated neurological significance.
Topics: Alzheimer Disease; Brain; Cognition; Homocysteine; Humans; Incidence; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2013 |
Lifetime requirement of the methionine cycle for neuronal development and maintenance.
Topics: Developmental Disabilities; Female; Folic Acid; Homocysteine; Humans; Methionine; Pregnancy; Prenatal Care; S-Adenosylmethionine; Vitamin B 12; Vitamin B Complex | 2014 |
Homocysteine excess: delineating the possible mechanism of neurotoxicity and depression.
Topics: Cysteine; Depression; Homocysteine; Humans; Hyperhomocysteinemia; Neurotoxicity Syndromes; S-Adenosylmethionine | 2015 |
S-Adenosyl Methionine in the Therapy of Depression and Other Psychiatric Disorders.
Topics: Animals; Depression; DNA Methylation; Epigenesis, Genetic; Homocysteine; Humans; Mental Disorders; Methylation; S-Adenosylmethionine; Time Factors | 2016 |
Consensus recommendations for the diagnosis, treatment and follow-up of inherited methylation disorders.
Topics: Consensus; Homocysteine; Humans; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methionine Adenosyltransferase; Methylation; Neonatal Screening; S-Adenosylhomocysteine; S-Adenosylmethionine | 2017 |
Lean Body Mass Harbors Sensing Mechanisms that Allow Safeguarding of Methionine Homeostasis.
Topics: Betaine-Homocysteine S-Methyltransferase; Biomarkers; Body Composition; Body Mass Index; Cystathionine beta-Synthase; Diet, Protein-Restricted; Dietary Proteins; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Liver; Methionine; S-Adenosylmethionine | 2017 |
Metabolism of Sulfur-Containing Amino Acids: How the Body Copes with Excess Methionine, Cysteine, and Sulfide.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Cystathionine beta-Synthase; Cysteine; Glycine N-Methyltransferase; Homocysteine; Humans; Hydrogen Sulfide; Liver; Methionine; S-Adenosylmethionine; Serine; Sulfides; Sulfur; Thiosulfates | 2020 |
Lessons Learned from Inherited Metabolic Disorders of Sulfur-Containing Amino Acids Metabolism.
Topics: Amino Acids, Sulfur; Animals; Brain Diseases; Cysteine; Glutathione; Homocysteine; Homocystinuria; Humans; Hydrogen Sulfide; Liver; Metabolic Diseases; Metabolism, Inborn Errors; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Sulfites; Sulfur; Sulfur Compounds | 2020 |
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur | 2020 |
23 trial(s) available for homocysteine and s-adenosylmethionine
| Article | Year |
|---|---|
Metabolic consequences of folate-induced reduction of hyperhomocysteinemia in uremia.
Topics: Erythrocyte Membrane; Homocysteine; Humans; Membrane Proteins; Methionine; Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Uremia | 1997 |
Folate nutriture alters choline status of women and men fed low choline diets.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Choline; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipids; Male; Methionine; Methylation; Middle Aged; Nutritional Physiological Phenomena; Nutritional Status; Phosphatidylcholines; Reference Values; S-Adenosylmethionine | 1999 |
Measurement of plasma and intracellular S-adenosylmethionine and S-adenosylhomocysteine utilizing coulometric electrochemical detection: alterations with plasma homocysteine and pyridoxal 5'-phosphate concentrations.
Topics: Adult; Chromatography, High Pressure Liquid; Electrochemistry; Female; Homocysteine; Humans; Indicators and Reagents; Liver; Lymphocytes; Middle Aged; Pyridoxal Phosphate; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Sensitivity and Specificity; Trichloroacetic Acid | 2000 |
Homocysteine, folate, methylation, and monoamine metabolism in depression.
Topics: Adult; Biogenic Monoamines; Blood Cell Count; Body Weight; Depression; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Methylation; Middle Aged; S-Adenosylmethionine; Vitamin B 12 | 2000 |
Genomic DNA methylation decreases in response to moderate folate depletion in elderly women.
Topics: Aged; Aged, 80 and over; Dietary Supplements; DNA; DNA Methylation; DNA-Cytosine Methylases; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Least-Squares Analysis; Leukocytes; Middle Aged; Nutrition Policy; S-Adenosylmethionine; Scintillation Counting; Statistics, Nonparametric | 2000 |
Blood S-adenosylmethionine concentrations and lymphocyte methylenetetrahydrofolate reductase activity in diabetes mellitus and diabetic nephropathy.
Topics: Adult; Albuminuria; Creatinine; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Disease Progression; Erythrocytes; Female; Homocysteine; Humans; Lymphocytes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Reference Values; Regression Analysis; Renal Dialysis; S-Adenosylhomocysteine; S-Adenosylmethionine | 2001 |
Plasma homocysteine and S-adenosylmethionine in erythrocytes as determinants of carotid intima-media thickness: different effects in diabetic and non-diabetic individuals. The Hoorn Study.
Topics: Aged; Arteriosclerosis; Carotid Arteries; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Erythrocytes; Female; Homocysteine; Humans; Male; Middle Aged; S-Adenosylmethionine; Tunica Intima; Tunica Media; Vitamin B 12; Vitamin B 6 | 2003 |
Treatment of AIDS-associated myelopathy with L-methionine: a placebo-controlled study.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Double-Blind Method; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Muscles; Neural Conduction; S-Adenosylmethionine; Spinal Cord Diseases; Urination | 2004 |
S-adenosylmethionine and 5-methyltetrahydrofolate are associated with endothelial function after controlling for confounding by homocysteine: the Hoorn Study.
Topics: Aged; Brachial Artery; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nitroglycerin; Regional Blood Flow; Risk Factors; S-Adenosylmethionine; Tetrahydrofolates; Ultrasonography; Vasodilation; Vasodilator Agents; Vitamin B 12; Vitamin B 6 | 2005 |
Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia.
Topics: Acetylcysteine; Adult; Arginine; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Cystathionine; Cysteine; Dipeptides; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Male; Methionine; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vasodilation | 2005 |
Effect of acute hyperhomocysteinemia on methylation potential of erythrocytes and on DNA methylation of lymphocytes in healthy male volunteers.
Topics: Adult; Cross-Over Studies; DNA Methylation; Erythrocytes; Genotype; Half-Life; Heterozygote; Homocysteine; Humans; Inulin; Kinetics; Lymphocytes; Male; S-Adenosylmethionine | 2005 |
Kinetics of homocysteine metabolism after moderate alcohol consumption.
Topics: Aged; Amino Acids, Sulfur; Beer; Central Nervous System Depressants; Cross-Over Studies; Diet; Ethanol; Female; Homocysteine; Humans; Kinetics; Male; Middle Aged; S-Adenosylmethionine; Vitamin B Complex | 2005 |
Marked elevation in homocysteine and homocysteine sulfinic acid in the cerebrospinal fluid of lymphoma patients receiving intensive treatment with methotrexate.
Topics: Adult; Aged; Alleles; Antimetabolites, Antineoplastic; Brain Chemistry; Central Nervous System Neoplasms; Cytarabine; Excitatory Amino Acids; Female; Homocysteine; Humans; Injections, Intravenous; Injections, Intraventricular; Lymphoma; Male; Methotrexate; Middle Aged; Neurotoxicity Syndromes; Pilot Projects; S-Adenosylmethionine; Statistics, Nonparametric; Time Factors | 2007 |
Dietary supplement S-adenosyl-L-methionine (AdoMet) effects on plasma homocysteine levels in healthy human subjects: a double-blind, placebo-controlled, randomized clinical trial.
Topics: Adolescent; Adult; Alanine Transaminase; C-Reactive Protein; Cholesterol; Dietary Supplements; Double-Blind Method; Female; Homocysteine; Humans; Male; Middle Aged; S-Adenosylmethionine; Young Adult | 2009 |
Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine.
Topics: Acute Coronary Syndrome; Aged; Betaine; Clofibric Acid; Cohort Studies; Diabetes Complications; Female; Homocysteine; Humans; Hypolipidemic Agents; Lipids; Male; S-Adenosylmethionine; Stroke | 2009 |
Homocysteine-lowering vitamins do not lower plasma S-adenosylhomocysteine in older people with elevated homocysteine concentrations.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vascular Diseases; Vitamin B 12; Vitamin B 6; Vitamins | 2010 |
Blood folate status and expression of proteins involved in immune function, inflammation, and coagulation: biochemical and proteomic changes in the plasma of humans in response to long-term synthetic folic acid supplementation.
Topics: Adult; Blood Coagulation; Blood Proteins; Dietary Supplements; Drug Administration Schedule; Female; Folic Acid; Homocysteine; Humans; Immunity; Inflammation; Male; Proteome; Proteomics; S-Adenosylmethionine; Tetrahydrofolates | 2010 |
Concentrations of unmetabolized folic acid and primary folate forms in plasma after folic acid treatment in older adults.
Topics: Aged; Aged, 80 and over; Aging; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B Complex | 2011 |
Bioavailability of S-adenosyl methionine and impact on response in a randomized, double-blind, placebo-controlled trial in major depressive disorder.
Topics: Biological Availability; Depressive Disorder, Major; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Psychiatric Status Rating Scales; S-Adenosylhomocysteine; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Tetrahydrofolates | 2012 |
Effect of 1 year B and D vitamin supplementation on LINE-1 repetitive element methylation in older subjects.
Topics: Aged; Aged, 80 and over; Calcium Carbonate; Cholecalciferol; Dietary Supplements; DNA Methylation; Drug Administration Schedule; Female; Homocysteine; Humans; Long Interspersed Nucleotide Elements; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B Complex | 2013 |
Short-term creatine supplementation does not reduce increased homocysteine concentration induced by acute exercise in humans.
Topics: Adolescent; Creatine; Cysteine; Dietary Supplements; Double-Blind Method; Energy Intake; Exercise; Feeding Behavior; Folic Acid; Glycine; Healthy Volunteers; Homocysteine; Humans; Male; Methionine; S-Adenosylmethionine; Soccer; Vitamin B 12 | 2014 |
Low-Dose Creatine Supplementation Lowers Plasma Guanidinoacetate, but Not Plasma Homocysteine, in a Double-Blind, Randomized, Placebo-Controlled Trial.
Topics: Adult; Bangladesh; Biomarkers; Cohort Studies; Creatine; Dietary Supplements; Double-Blind Method; Down-Regulation; Female; Folic Acid; Glycine; Homocysteine; Humans; Hyperhomocysteinemia; Intention to Treat Analysis; Male; Middle Aged; Patient Dropouts; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial.
Topics: Betaine; Child; Cystathionine beta-Synthase; Homocysteine; Homocystinuria; Humans; Methionine; Prospective Studies; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2022 |
401 other study(ies) available for homocysteine and s-adenosylmethionine
| Article | Year |
|---|---|
Two newborns with nutritional vitamin B12 deficiency: challenges in newborn screening for vitamin B12 deficiency.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Anemia, Pernicious; Autoimmune Diseases; Biomarkers; Carnitine; Citrates; Cystathionine; False Negative Reactions; Female; Gastric Bypass; Heterozygote; Homocysteine; Humans; Hydroxocobalamin; Infant Food; Infant, Newborn; Malabsorption Syndromes; Male; Mass Spectrometry; Maternal-Fetal Exchange; Methylmalonic Acid; Neonatal Screening; Pregnancy; Pregnancy Complications; Vitamin B 12 Deficiency | 2005 |
Inherited metabolic disorders in Turkish patients with autism spectrum disorders.
Topics: Adolescent; Adult; Amino Acids; Ammonia; Autism Spectrum Disorder; Blood Gas Analysis; Carnitine; Child; Child, Preschool; Comorbidity; Female; Glycosaminoglycans; Homocysteine; Humans; Infant; Lactic Acid; Male; Metabolism, Inborn Errors; Prevalence; Retrospective Studies; Tandem Mass Spectrometry; Turkey; Young Adult | 2016 |
Proteinuria as a presenting sign of combined methylmalonic acidemia and homocysteinemia: case report.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Base Sequence; Carnitine; Child, Preschool; DNA; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Proteinuria | 2020 |
Purification and properties of S-adenosyl-L-homocysteine hydrolase from leaves of spinach beet.
Topics: Adenine; Cysteine; Deoxyadenosines; Homocysteine; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Methionine; Plants; S-Adenosylhomocysteine; S-Adenosylmethionine | 1976 |
[Effects of S-adenosylmethionine and S-adenosylhomocysteine on in vivo synthesis of noradrenaline and serotonin in different parts of the rat brain].
Topics: Animals; Brain; Homocysteine; Norepinephrine; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Serotonin | 1979 |
Deficiency of S-adenosylmethionine-homocysteine methyltransferase activity in hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Female; Homocysteine; Hydrolases; Liver; Liver Neoplasms; Methyltransferases; Neoplasms, Experimental; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1977 |
Inhibition of lymphocyte-mediated cytolysis by 3-deazaadenosine: evidence for a methylation reaction essential to cytolysis.
Topics: Cyclic AMP; Cytotoxicity, Immunologic; Homocysteine; Immunity, Cellular; Isomerism; Methyltransferases; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine; T-Lymphocytes; Tubercidin | 1978 |
N5-Methyltetrahydrofolate-homocysteine cobalamin methyltransferase activity in chronic erythremic myelosis (Di Guglielmo syndrome).
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Pernicious; Apoenzymes; Bone Marrow; Homocysteine; Humans; Leukemia, Erythroblastic, Acute; Methyltransferases; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1977 |
"Pretranscriptional capping" in the biosynthesis of cytoplasmic polyhedrosis virus mRNA.
Topics: Adenylyl Imidodiphosphate; Base Sequence; Guanine Nucleotides; Homocysteine; Insect Viruses; Methylation; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcription, Genetic | 1978 |
S-adenosyl-L-homocysteine as a stimulator of viral RNA synthesis by two distinct cytoplasmic polyhedrosis viruses.
Topics: Adenosine; Cell-Free System; Homocysteine; Insect Viruses; Methylation; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; Stimulation, Chemical | 1978 |
Relationship between tissue levels of S-adenosylmethionine, S-adenylhomocysteine, and transmethylation reactions.
Topics: Aging; Animals; Female; Homocysteine; Liver; Methylation; Methyltransferases; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1979 |
Inhibition of methylation by adenosine in adenosine deaminase-inhibited, phytohemagglutinin-stimulated human lymphocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; DNA; Homocysteine; Humans; Lymphocyte Activation; Methylation; Nucleoside Deaminases; Phytohemagglutinins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1979 |
De novo synthesis of methionine in normal and Brugia-infected Aedes aegypti.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aedes; Animals; Brugia; Cell-Free System; Female; Filarioidea; Homocysteine; Male; Methionine; Molecular Weight; S-Adenosylmethionine; Tetrahydrofolates; Tissue Extracts; Vitamin B 12 | 1979 |
Inhibition of immune cell function by adenosine: biochemical studies.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Adenosine; Animals; Cytotoxicity, Immunologic; Homocysteine; Imidazoles; Lymphocytes; Methionine; Mice; S-Adenosylmethionine; Theophylline; Uridine | 1979 |
The relation between purine metabolism and flavinogenesis in Eremothecium ashbyii. The identification of S-adenosylmethionine and S-adenosylhomocysteine accumulated in non-growing cells of E. ashbyii.
Topics: Adenine; Ascomycota; Culture Media; Dose-Response Relationship, Drug; Homocysteine; Riboflavin; S-Adenosylhomocysteine; S-Adenosylmethionine; Saccharomycetales | 1977 |
Tissue distribution of S-adenosylmethionine and S-adenosylhomocysteine in the rat. Effect of age, sex and methionine administration on the metabolism of S-adenosylmethionine, S-adenosylhomocysteine and polyamines.
Topics: Age Factors; Animals; Brain; Glycine; Homocysteine; Hydrolases; Kidney; Liver; Methionine; Methionine Adenosyltransferase; Polyamines; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors | 1977 |
Affinity labeling of histamine N-methyltransferase by 2',3'-dialdehyde derivatives of S-adenosylhomocysteine and S-adenosylmethionine. Kinetics of inactivation.
Topics: Affinity Labels; Chemical Phenomena; Chemistry; Histamine N-Methyltransferase; Homocysteine; Kinetics; Magnetic Resonance Spectroscopy; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrophotometry, Infrared; Structure-Activity Relationship | 1978 |
Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 7. Role of the ribosyl moiety in enzymatic binding of S-adenosyl-L-homocysteine and S-adenosyl-L-methionine.
Topics: Animals; Cattle; Guinea Pigs; Homocysteine; In Vitro Techniques; Male; Methods; Methyltransferases; Oxidation-Reduction; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1978 |
[New studies on inhibition of tRNA N2 guanine methyltransferase by S-adenosyl-homocysteine and S-adenosyl-methionine analogs].
Topics: Animals; Escherichia coli; Guanine; Homocysteine; Kinetics; Liver; Rabbits; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; tRNA Methyltransferases | 1976 |
S-Adenosyl-L-homocysteine hydrolase: analogues of S-adenosyl-L-homocysteine as potential inhibitors.
Topics: Animals; Cattle; Homocysteine; Hydrolases; In Vitro Techniques; Liver; Male; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1977 |
The enzymatic synthesis of S-adenosyl-L-[2(n)-3H]homocysteine.
Topics: Animals; Glycine; Homocysteine; Hydrolases; Liver; Methyltransferases; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1977 |
S-adenosyl-L-homocysteine dialdehyde: an affinity labeling reagent for histamine-N-methyltransferase.
Topics: Affinity Labels; Animals; Binding Sites; Brain; Guinea Pigs; Histamine N-Methyltransferase; Homocysteine; Kinetics; Mathematics; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1977 |
[New syntheses of S-adenosylhomocysteine and S-adenosylmethionine analogs].
Topics: Homocysteine; Methods; S-Adenosylhomocysteine; S-Adenosylmethionine | 1976 |
Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 4. Further modifications of the amino and base portions of S-adenosyl-L-homocysteine.
Topics: Animals; Binding Sites; Cattle; Guinea Pigs; Homocysteine; In Vitro Techniques; Male; Methyltransferases; Rabbits; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1976 |
A new method for the assay of tissue. S-adenosylhomocysteine and S-adenosylmethione. Effect of pyridoxine deficiency on the metabolism of S-adenosylhomocysteine, S-adenosylmethionine and polyamines in rat liver.
Topics: Adenosylmethionine Decarboxylase; Animals; Chromatography; Homocysteine; Liver; Male; Polyamines; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Vitamin B 6 Deficiency | 1976 |
Tetrahydrofolic acid: an inhibitor of the methyltetrahydrofolic acid-mediated methylation of indolethylamines.
Topics: Adenosine; Animals; Binding, Competitive; Bufotenin; Ethylamines; Homocysteine; Indoles; Lung; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Rabbits; S-Adenosylmethionine; Serotonin; Tetrahydrofolates | 1975 |
The S-n-propyl analogue of S-adenosylmethionine.
Topics: Acetates; Adenosine; Guanidines; Histamine; Homocysteine; Methyltransferases; S-Adenosylmethionine; Saccharomyces cerevisiae; Serotonin; Structure-Activity Relationship; Sulfides | 1975 |
Existence of two levels of repression in the biosynthesis of methionine in Saccharomyces cerevisiae: effect of lomofungin on enzyme synthesis.
Topics: Antifungal Agents; Cycloheximide; Enzyme Repression; Fungal Proteins; Homocysteine; Homoserine; Lyases; Methionine; Phenazines; RNA; RNA, Messenger; S-Adenosylmethionine; Saccharomyces cerevisiae | 1975 |
Specificity and genetics of S-adenosylmethionine transport in Saccharomyces cerevisiae.
Topics: Bacterial Proteins; Binding Sites; Binding, Competitive; Biological Transport, Active; Ethionine; Genes; Genetic Linkage; Homocysteine; Kinetics; Mutation; Protein Conformation; S-Adenosylmethionine; Saccharomyces cerevisiae; Structure-Activity Relationship | 1975 |
Studies on the kinetic mechanism of S-adenosylmethionine: protein O-methyltransferase of calf thymus.
Topics: Animals; Cattle; Homocysteine; Kinetics; Mathematics; Methyltransferases; Ribonucleases; S-Adenosylmethionine; Thymus Gland | 1975 |
Regulation of cyclopropane fatty acid biosynthesis by variations in enzyme activities.
Topics: Adenosine; Cell Division; Cyclopropanes; Fatty Acids; Homocysteine; Lactobacillus; Methyltransferases; N-Glycosyl Hydrolases; S-Adenosylmethionine; Time Factors | 1975 |
Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 3. Modifications of the sugar portion of S-adenosylhomocysteine.
Topics: Adenosine; Adrenal Medulla; Animals; Binding Sites; Brain; Catechol O-Methyltransferase Inhibitors; Cattle; Deoxy Sugars; Guinea Pigs; Homocysteine; Liver; Magnetic Resonance Spectroscopy; Male; Methyltransferases; Phenylethanolamine N-Methyltransferase; Pineal Gland; Rats; S-Adenosylmethionine; Serotonin | 1975 |
Adenine nucleosides in solution: circular dichroism studies and base conformation.
Topics: Adenosine; Adenosine Monophosphate; Anti-Bacterial Agents; Circular Dichroism; Homocysteine; Molecular Conformation; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1975 |
A rapid liquid chromatographic determination of S-adenosylhomocysteine in subgram amounts of tissue.
Topics: Animals; Chromatography, High Pressure Liquid; Ethionine; Female; Homocysteine; Liver; Mice; Mice, Inbred C57BL; Microchemistry; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1975 |
Physiological analysis of mutants of Saccharomyces cerevisiae impaired in sulphate assimilation.
Topics: Cysteine; Genes, Fungal; Homocysteine; Methionine; Mutation; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfates; Sulfides; Sulfites; Thiosulfates | 1992 |
Identification of the structural gene for glucose-6-phosphate dehydrogenase in yeast. Inactivation leads to a nutritional requirement for organic sulfur.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cysteine; Escherichia coli; Gene Expression Regulation, Fungal; Genes, Fungal; Genotype; Glucosephosphate Dehydrogenase; Glutathione; Homocysteine; Humans; Kinetics; Methionine; Molecular Sequence Data; Mutagenesis; Phenotype; Restriction Mapping; S-Adenosylmethionine; Saccharomyces cerevisiae; Sequence Homology, Nucleic Acid; Transcription, Genetic | 1991 |
Mechanism of antiviral and cytotoxic action of (+/-)-6' beta-fluoroaristeromycin, a potent inhibitor of S-adenosylhomocysteine hydrolase.
Topics: Adenine; Adenosylhomocysteinase; Animals; Antiviral Agents; Cell Division; Homocysteine; Hydrolases; Mice; Nucleic Acids; Phosphorylation; Protein Biosynthesis; S-Adenosylhomocysteine; S-Adenosylmethionine | 1991 |
Inhibitors of membrane transmethylation reactions prevent the lymphocyte chemokinetic response.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Bradykinin; Chemotaxis, Leukocyte; Colchicine; Homocysteine; Humans; Interleukin-16; Leukocytes, Mononuclear; Lymphocytes; Lymphokines; Male; Membrane Lipids; Methylation; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Second Messenger Systems | 1990 |
Mechanism of the synergistic antiviral and cytostatic activity of (RS)-3-(adenin-9-yl)-2-hydroxypropanoic acid isobutyl ester and D,L-homocysteine.
Topics: Adenine; Adenosylhomocysteinase; Animals; Antiviral Agents; Cell Line; Drug Synergism; Homocysteine; Hydrolases; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Vaccinia virus | 1990 |
Reversion to a homocysteine-responsive phenotype in a human melanoma cell line is associated with diminished growth potential and increased methionine biosynthesis.
Topics: Adenosine; Cell Division; Culture Media; Deoxyadenosines; Homocysteine; Humans; Melanoma, Experimental; Methionine; Phenotype; S-Adenosylmethionine; Tetrahydrofolates; Thionucleosides; Tumor Cells, Cultured | 1990 |
Cobalamin neuropathy. Is S-adenosylhomocysteine toxicity a factor?
Topics: Animals; Brain Chemistry; Chiroptera; Chromatography, High Pressure Liquid; Homocysteine; Liver; Methionine; Neuromuscular Diseases; S-Adenosylhomocysteine; S-Adenosylmethionine; Valine; Vitamin B 12 Deficiency | 1990 |
Combined modulation of S-adenosylmethionine biosynthesis and S-adenosylhomocysteine metabolism enhances inhibition of nucleic acid methylation and L1210 cell growth.
Topics: Adenosine; Animals; Cell Division; DNA, Neoplasm; Homocysteine; Leukemia L1210; Methylation; Polyamines; RNA, Neoplasm; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 1990 |
IgE-dependent activation of mast cells is not associated with enhanced phospholipid methylation.
Topics: Animals; Cyclic AMP; Histamine Release; Homocysteine; Immunoglobulin E; In Vitro Techniques; Male; Mast Cells; Methionine; Methylation; Phosphatidylserines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Tritium; Tubercidin | 1986 |
Effects of 9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl)-adenine and -3-deazaadenine on the metabolism of S-adenosylhomocysteine in mouse L929 cells.
Topics: Adenosine; Adenosine Kinase; Adenosylhomocysteinase; Animals; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Homocysteine; Hydrolases; Mice; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1988 |
Protooncogene methylation and expression in regenerating liver and preneoplastic liver nodules induced in the rat by diethylnitrosamine: effect of variations of S-adenosylmethionine:S-adenosylhomocysteine ratio.
Topics: Animals; Diethylnitrosamine; Genes, ras; Homocysteine; Immunoblotting; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Methylation; Precancerous Conditions; Proto-Oncogenes; Rats; Rats, Inbred F344; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Biochemical analysis of the role of transmethylation in the methionine dependence of tumor cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biogenic Polyamines; Cell Division; Culture Media; Cystathionine beta-Synthase; Homocysteine; Humans; Methionine; Methionine Adenosyltransferase; Methylation; Phenotype; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1989 |
Hepatic content of S-adenosylmethionine, S-adenosylhomocysteine and glutathione in rats receiving treatments modulating methyl donor availability.
Topics: Animals; Biomarkers; Choline Deficiency; Cysteine; Diet; Fatty Liver; Folic Acid Deficiency; Glutathione; Homocysteine; Lipids; Liver; Male; Methionine; Methylation; Niacinamide; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Agarose-selected variants of two human tumor cell lines exhibit altered methionine auxotrophy.
Topics: Cell Line; Cell Transformation, Neoplastic; Genetic Variation; Homocysteine; Humans; Melanoma; Methionine; Neuroblastoma; Nucleic Acids; S-Adenosylmethionine; Sepharose; Tumor Cells, Cultured | 1989 |
S-adenosylmethionine, S-adenosylhomocysteine and adenosine system. Age-dependent availability in rat brain.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Brain; Homocysteine; In Vitro Techniques; Kinetics; Male; Membranes; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Regulation of S-adenosyl methionine synthesis in the mouse embryo.
Topics: Animals; Binding, Competitive; Blastocyst; Embryo, Mammalian; Ethionine; Homocysteine; Humans; Methionine; Methylation; Mice; Mice, Inbred Strains; Morula; Oocytes; S-Adenosylmethionine | 1989 |
Elucidation of the mechanism by which homocysteine potentiates the anti-vaccinia virus effects of the S-adenosylhomocysteine hydrolase inhibitor 9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl)-adenine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Antiviral Agents; Drug Synergism; Homocysteine; Hydrolases; L Cells; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Vaccinia virus | 1989 |
S-adenosylmethionine, S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase variations during differentiation of Dictyostelium discoideum.
Topics: Adenosylhomocysteinase; Cell Differentiation; Cyclic AMP; Dictyostelium; Genetic Variation; Homocysteine; Hydrolases; S-Adenosylhomocysteine; S-Adenosylmethionine | 1988 |
Altered methionine metabolism in metastatic variants of a human melanoma cell line.
Topics: Cell Division; Culture Media; Homocysteine; Humans; Melanoma; Methionine; Neoplasm Metastasis; S-Adenosylmethionine; Tumor Cells, Cultured; Vitamin B 12 | 1989 |
S-adenosylmethionine, S-adenosylhomocysteine and DNA methylation levels in the liver of rats fed methapyrilene and analogs.
Topics: Aminopyridines; Animals; Carcinogens; Deoxycytidine; DNA; Homocysteine; Liver; Male; Methapyrilene; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Evidence for altered methionine methyl-group utilization in the diabetic rat's brain.
Topics: Administration, Oral; Animals; Brain; Caseins; Diabetes Mellitus, Experimental; Diet; Female; Homocysteine; Male; Methionine; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Streptozocin; Time Factors | 1988 |
Modulation by the ratio S-adenosylmethionine/S-adenosylhomocysteine of cyclic AMP-dependent phosphorylation of the 50 kDa protein of rat liver phospholipid methyltransferase.
Topics: Animals; Cyclic AMP; Fluorides; Homocysteine; Kinetics; Liver; Methyltransferases; Molecular Weight; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylethanolamine N-Methyltransferase; Phosphorylation; Protein Kinases; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1985 |
Regulation of mononuclear leukocyte function by transmethylation reactions.
Topics: Animals; Cell Migration Inhibition; Enzyme Activation; Guinea Pigs; Homocysteine; Macrophages; Methylation; Oxygen; Phospholipases; S-Adenosylmethionine; Superoxides | 1985 |
Effects of the transmethylation inhibitor S-adenosyl-homocysteine and of the methyl donor S-adenosyl-methionine on rat Leydig cell function in vitro.
Topics: Animals; Bucladesine; Cell Membrane; Chorionic Gonadotropin; Cyclic AMP; Dose-Response Relationship, Drug; Homocysteine; Leydig Cells; Luteinizing Hormone; Male; Methylation; Rats; Receptors, LH; S-Adenosylhomocysteine; S-Adenosylmethionine; Testosterone | 1987 |
Effect of dietary cystine on methionine metabolism in rat liver.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Cystine; Dietary Proteins; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Serine | 1986 |
Methylation deficiency causes vitamin B12-associated neuropathy in the pig.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Homocysteine; Methylation; Nervous System Diseases; Nitrous Oxide; S-Adenosylhomocysteine; S-Adenosylmethionine; Spinal Cord; Swine; Vitamin B 12 | 1988 |
Growth support and toxicity of homocysteine and its effects on methionine metabolism in non-transformed and chemically transformed C3H/10T1/2 cells.
Topics: Animals; Cell Division; Cell Line; Cysteine; Dose-Response Relationship, Drug; Glutathione; Homocysteine; Homocystine; Methionine; Mice; Mice, Inbred C3H; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1988 |
Differential metabolic response of rat liver, kidney and spleen to ethionine exposure. S-adenosylamino acids, homocysteine and reduced glutathione in tissues.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Ethionine; Glutathione; Homocysteine; Kidney; Liver; Male; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Spleen; Time Factors | 1988 |
Effect of methotrexate on homocysteine and other sulfur compounds in tissues of rats fed a normal or a defined, choline-deficient diet.
Topics: Analysis of Variance; Animals; Choline Deficiency; Diet; Glutathione; Homocysteine; Kidney; Liver; Male; Methotrexate; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 1988 |
Methionine metabolism in mammals. The methionine-sparing effect of cystine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine; Cystathionine beta-Synthase; Cystine; Diet; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1988 |
1,2-Dimethylhydrazine-induced premalignant alterations in the S-adenosylmethionine/S-adenosylhomocysteine ratio and membrane lipid lateral diffusion of the rat distal colon.
Topics: 1,2-Dimethylhydrazine; Animals; Colonic Neoplasms; Decanoic Acids; Diffusion; Dimethylhydrazines; Homocysteine; Membrane Lipids; Methionine Adenosyltransferase; Methylhydrazines; Precancerous Conditions; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1988 |
Disposition of endogenous homocysteine by mouse fibroblast C3H/10T1/2 Cl 8 and the chemically transformed C3H/10T1/2 MCA Cl 16 cells following methotrexate exposure.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Chromatography, Ion Exchange; Culture Media; Fibroblasts; Homocysteine; Methotrexate; Methylcholanthrene; Mice; Mice, Inbred C3H; Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1986 |
4'-Thioadenosine as a novel inhibitor of S-adenosylhomocysteine hydrolase and an inducer for the differentiation of HL-60 human leukemia cells.
Topics: Adenosine; Adenosylhomocysteinase; Cell Differentiation; Cell Line; Chromatography, High Pressure Liquid; Homocysteine; Humans; Hydrolases; Leukemia, Myeloid, Acute; Purine Nucleotides; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1986 |
Isozyme-specific enzyme inhibitors. 13. S-[5'(R)-[(N-triphosphoamino)methyl]adenosyl]-L-homocysteine, a potent inhibitor of rat methionine adenosyltransferases.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Chemical Phenomena; Chemistry; Homocysteine; Isoenzymes; Kinetics; Methionine; Methionine Adenosyltransferase; Polyphosphates; Rats; S-Adenosylmethionine; Transferases | 1987 |
Methionine metabolism in isolated perfused livers from rats fed on zinc-deficient and restricted diets.
Topics: Animals; Butyrates; Cystathionine; Diet; Homocysteine; In Vitro Techniques; Liver; Male; Methionine; Perfusion; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Zinc | 1986 |
Resistance to multiple adenine nucleoside and methionine analogues in mutant murine lymphoma cells with enlarged S-adenosylmethionine pools.
Topics: Adenosine; Animals; Cells, Cultured; Drug Resistance; Homocysteine; Kinetics; Lymphoma; Methionine; Methionine Adenosyltransferase; Mice; Mutation; S-Adenosylhomocysteine; S-Adenosylmethionine | 1986 |
In vivo depletion of S-adenosyl-L-homocysteine and S-adenosyl-L-methionine in guinea pig lung after chronic S-(-)-nicotine administration.
Topics: Animals; Chromatography, High Pressure Liquid; Guinea Pigs; Homocysteine; Injections, Subcutaneous; Liver; Lung; Male; Nicotine; S-Adenosylhomocysteine; S-Adenosylmethionine; Stereoisomerism | 1986 |
Disposition of homocysteine and S-3-deazaadenosylhomocysteine in cells exposed to 3-deazaadenosine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Fibroblasts; Homocysteine; Hydrolases; Liver; Mice; Neoplasms, Experimental; Protein Binding; Rats; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1986 |
Inhibition of antibody production by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Antibody Formation; B-Lymphocytes; Cells, Cultured; DNA Replication; Homocysteine; Immunosuppressive Agents; Lymphocyte Activation; Male; Methylation; Mice; S-Adenosylmethionine | 1985 |
Determination of in vivo protein binding of homocysteine and its relation to free homocysteine in the liver and other tissues of the rat.
Topics: Adenine; Animals; Dithioerythritol; Half-Life; Homocysteine; Liver; Methionine; Methods; Proteins; Rats; S-Adenosylmethionine; Sulfur; Time Factors; Tissue Distribution | 1986 |
Effect of S-adenosylhomocysteine on sulfhydryl xenobiotic transmethylases in rat liver.
Topics: Animals; Homocysteine; Liver; Male; Methyltransferases; Microsomes, Liver; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1985 |
Phospholipid methylase activity, [3H]S-adenosyl-L-homocysteine binding, and S-adenosyl-L-methionine and S-adenosyl-L-homocysteine levels in rat brain during maturation.
Topics: Animals; Animals, Newborn; Brain; Cell Membrane; Cerebral Cortex; Homocysteine; Male; Methyltransferases; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylethanolamine N-Methyltransferase; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1985 |
The role of S-adenosylhomocysteine in the biological utilization of S-adenosylmethionine.
Topics: Alcaligenes; Animals; Dictyostelium; Homocysteine; Humans; Kinetics; Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine | 1985 |
The effect of diazepam on brain levels of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine: possible correlation with protection from methionine sulfoximine seizures.
Topics: Animals; Brain Chemistry; Diazepam; Dose-Response Relationship, Drug; Homocysteine; Male; Methionine Sulfoximine; Methylation; Mice; Reaction Time; S-Adenosylhomocysteine; S-Adenosylmethionine; Seizures | 1985 |
S-adenosylmethionine: protein-carboxyl methyltransferase from erythrocyte.
Topics: Animals; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Ion Exchange; Erythrocytes; Fibrinogen; gamma-Globulins; Homocysteine; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Kinetics; Male; Methyltransferases; Molecular Weight; Proteins; S-Adenosylmethionine; Species Specificity; Thymus Gland | 1974 |
Methylation of myelin basic protein by enzymes from rat brain.
Topics: Adenosine; Aging; Animals; Arginine; Brain; Carbon Radioisotopes; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cytoplasm; Homocysteine; Methylation; Methyltransferases; Microsomes; Mitochondria; Myelin Basic Protein; Myelin Sheath; Rats; Ribosomes; S-Adenosylmethionine; Time Factors; Tritium; Ultrafiltration | 1974 |
Folic acid metabolism in vitamin B12-deficient sheep. Effects of injected methionine on methotrexate transport and the activity of enzymes associated with folate metabolism in liver.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Female; Folic Acid; Homocysteine; Liver; Membranes; Methionine; Methotrexate; Methyltransferases; NAD; NADP; S-Adenosylmethionine; Serum Albumin, Bovine; Sheep; Tetrahydrofolate Dehydrogenase; Tritium; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
The deoxyribonucleic acid modification and restriction enzymes of Escherichia coli B.
Topics: Adenosine; Adenosine Triphosphatases; Carbon Isotopes; Chromatography, DEAE-Cellulose; Coliphages; Deoxyribonucleases; DNA, Bacterial; DNA, Viral; Endonucleases; Enzyme Activation; Escherichia coli; Ethionine; Homocysteine; Kinetics; Phosphorus Isotopes; S-Adenosylmethionine; Sulfides | 1972 |
Quantitative analysis of S-adenosylmethionine and S-adenosylhomocysteine in animal tissues.
Topics: Animals; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; Homocysteine; Hydrolysis; Liver; Methionine; Methods; Nucleosides; Perchlorates; Rabbits; Radioisotope Dilution Technique; Rats; S-Adenosylmethionine | 1971 |
Competing methyltransferase systems.
Topics: Adenosine; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Nucleus; Cytoplasm; Glycine; Homocysteine; Kidney; Liver; Liver Neoplasms; Methylation; Methyltransferases; Mice; Molecular Weight; Pancreas; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine | 1972 |
Effects of carcinogens and other agents on histone methylation by a histone arginine methyltransferase purified from rat liver cytoplasm.
Topics: Acridines; Adenine; Adenosine; Animals; Arginine; Azo Compounds; Carbon Radioisotopes; Carcinogens; Cytoplasm; Dimethylformamide; Ethidium; Ethionine; Fluorenes; Histones; Homocysteine; Liver; Male; Mesylates; Methylation; Methyltransferases; Nitrosamines; Nitrosoguanidines; Nitrosourea Compounds; Pyrimidines; Pyrroles; Rats; Ribonucleosides; S-Adenosylmethionine | 1974 |
Effects of carcinogens and other agents on histone methylation in rat liver nuclei by endogenous histone lysine methyltransferase.
Topics: Adenosine; Animals; Azo Compounds; Benz(a)Anthracenes; Carbon Radioisotopes; Carcinogens; Cell Nucleus; Dimethylformamide; Ethionine; Fluorenes; Histones; Homocysteine; Liver; Lysine; Mesylates; Methylation; Methyltransferases; Nitrosamines; Nitrosoguanidines; Nitrosourea Compounds; Pyrimidines; Pyrroles; Rats; Ribonucleosides; S-Adenosylmethionine | 1974 |
Active transport of exogenous S-adenosylmethionine and related compounds into cells and vacuoles of Saccharomyces cerevisiae.
Topics: Aerobiosis; Biological Transport, Active; Buffers; Carbon Radioisotopes; Ethionine; Glucose; Homocysteine; Inclusion Bodies; Microscopy, Ultraviolet; Phosphates; S-Adenosylmethionine; Saccharomyces cerevisiae; Stereoisomerism; Vacuoles | 1974 |
In vitro synthesis of methylated messenger RNA by the virion-associated RNA polymerase of vesicular stomatitis virus.
Topics: Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; DNA-Directed RNA Polymerases; Homocysteine; Methylation; Phosphorus Radioisotopes; Ribonucleotides; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; Tritium; Uracil Nucleotides; Vesicular stomatitis Indiana virus; Viral Proteins | 1974 |
Mammalian methylenetetrahydrofolate reductase. Partial purification, properties, and inhibition by S-adenosylmethionine.
Topics: Adenosine; Alcohol Oxidoreductases; Ammonium Sulfate; Animals; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Drug Stability; Flavin-Adenine Dinucleotide; Folic Acid; Formaldehyde; Homocysteine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Liver; NAD; NADP; Rats; S-Adenosylmethionine; Spectrophotometry; Swine; Vitamin K | 1971 |
Vitamin B12-dependent methionine synthesis in Rhizobium meliloti.
Topics: Carbon Radioisotopes; Cell-Free System; Chromatography, Ion Exchange; Dithiothreitol; Flavin Mononucleotide; Homocysteine; Kinetics; Magnesium; Methionine; Methyltransferases; Oxidation-Reduction; Rhizobium; S-Adenosylmethionine; Tetrahydrofolates; Time Factors; Vitamin B 12 | 1974 |
5-methyltetrahydrofolate homocysteine cobalamin methyltransferase in human bone marrow and its relationship to pernicious anemia.
Topics: Anemia, Pernicious; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Cell-Free System; Chromatography, Ion Exchange; Erythrocytes; Homocysteine; Humans; Kinetics; Methyltransferases; S-Adenosylmethionine; Tetrahydrofolates; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Ethanol-induced changes in methionine metabolism in rat liver.
Topics: Animals; Cystathionine; Dietary Proteins; Ethanol; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; S-Adenosylmethionine | 1974 |
Analogs of S-adenosylhomocysteine as potential inhibitors of biological transmethylation. Inhibition of several methylases by S-tubercidinylhomocysteine.
Topics: Adenosine; Animals; Anti-Bacterial Agents; Catechol O-Methyltransferase Inhibitors; Homocysteine; Indoles; Kinetics; Liver; Lung; Methyltransferases; Pyrimidines; Pyrroles; Rabbits; Rats; Ribonucleosides; S-Adenosylmethionine; tRNA Methyltransferases | 1974 |
Ethanol preference in the rat following inhibition of liver alcohol dehydrogenase and S-adenosyl methionine.
Topics: Alcohol Drinking; Alcohol Oxidoreductases; Animals; Homocysteine; Homoserine; Liver; Male; Pyrazoles; Rats; S-Adenosylmethionine | 1974 |
Kinetics of product inhibition of rabbit lung N-methyltransferase.
Topics: Animals; Carbon Radioisotopes; Feedback; Homocysteine; Kinetics; Lung; Male; Methyltransferases; N,N-Dimethyltryptamine; Rabbits; S-Adenosylmethionine; Tryptamines | 1974 |
Transport of S-adenosylmethionine in Saccharomyces cerevisiae.
Topics: Adenosine; Azides; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Culture Media; Cyanides; Cycloheximide; Diploidy; Ethionine; Genes; Genetics, Microbial; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Membrane Transport Proteins; Methionine; Mutation; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Temperature | 1972 |
The mechanism of S-adenosyl-L-methionine synthesis by purified preparations of bakers' yeast.
Topics: Adenosine Triphosphate; Amino Acids; Ammonium Sulfate; Carbon Isotopes; Catalysis; Chemical Precipitation; Chromatography, Ion Exchange; Cyclopentanes; Enzyme Activation; Ethanol; Fluorine; Guanosine Triphosphate; Homocysteine; Kinetics; Methionine; Models, Chemical; Pentosyltransferases; Phosphoric Acids; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Sulfides | 1972 |
Regulation of homocysteine biosynthesis in Salmonella typhimurium.
Topics: Acyltransferases; Bacteriological Techniques; Carbon Isotopes; Enzyme Repression; Feedback; Genetics, Microbial; Homocysteine; Homoserine; Hydro-Lyases; L-Serine Dehydratase; Lyases; Methionine; Molecular Biology; Mutation; S-Adenosylmethionine; Salmonella typhimurium; Spectrophotometry; Succinates; Tetrahydrofolates; Tritium; Vitamin B 12 | 1972 |
The deoxyribonucleic acid modification and restriction enzymes of Escherichia coli B. I. Purification, subunit structure, and catalytic properties of the modification methylase.
Topics: Adenosine; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Coliphages; DNA; DNA, Bacterial; DNA, Viral; Drug Stability; Electrophoresis, Disc; Escherichia coli; Ethionine; Homocysteine; Hydrogen-Ion Concentration; Macromolecular Substances; Methyltransferases; Molecular Weight; Osmolar Concentration; S-Adenosylmethionine; Sodium Dodecyl Sulfate; Species Specificity; Sulfides; Tritium | 1972 |
The deoxyribonucleic acid modification and restriction enzymes of Escherichia coli B. II. Purification, subunit structure, and catalytic properties of the restriction endonuclease.
Topics: Adenosine; Adenosine Triphosphate; Catalysis; Cations, Divalent; Centrifugation, Density Gradient; Coliphages; DNA, Bacterial; DNA, Viral; Electrophoresis, Disc; Endonucleases; Escherichia coli; Ethionine; Exonucleases; Homocysteine; Kinetics; Macromolecular Substances; Molecular Weight; Phosphorus Isotopes; S-Adenosylmethionine; Sodium Dodecyl Sulfate; Sulfides; Tritium | 1972 |
Methionine biosynthesis and S-adenosylmethionine degradation during an induced morphogenesis of Candida albicans.
Topics: Candida albicans; Carbon Isotopes; Cell-Free System; Culture Media; Glycine; Homocysteine; Methionine; Methyltransferases; Morphogenesis; S-Adenosylmethionine | 1973 |
Effects of regulatory mutations upon methionine biosynthesis in Saccharomyces cerevisiae: loci eth2-eth3-eth10.
Topics: Adenosine Triphosphate; Benzene; Cell-Free System; Enzyme Repression; Ethionine; Genes; Homocysteine; Methionine; Methyltransferases; Mutation; Nucleotidyltransferases; Oxidoreductases; S-Adenosylmethionine; Saccharomyces cerevisiae; Stereoisomerism; Sulfites; Transferases | 1973 |
Effect of methionine and vitamin B-12 on the activities of methionine biosynthetic enzymes in metJ mutants of Escherichia coli K12.
Topics: Adenosine Triphosphate; Culture Media; Cystathionine; Enzyme Repression; Escherichia coli; Folic Acid; Homocysteine; Hydro-Lyases; L-Serine Dehydratase; Methionine; Methyltransferases; Mutation; Oxidoreductases; S-Adenosylmethionine; Time Factors; Transferases; Vitamin B 12 | 1973 |
Induction and repression in the S-adenosylmethionine and methionine biosynthetic systems of Saccharomyces cerevisiae.
Topics: Adenosine Triphosphate; Carbon Radioisotopes; Culture Media; Enzyme Induction; Enzyme Repression; Homocysteine; Methionine; Methyltransferases; Nucleotidyltransferases; S-Adenosylmethionine; Saccharomyces cerevisiae; Time Factors | 1973 |
S-adenosylmethionine metabolism by members of the genus Candida.
Topics: Candida; Candida albicans; Carbon Radioisotopes; Cell-Free System; Chromatography; Culture Media; Homocysteine; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet | 1973 |
A coupled spectrophotometric enzyme assay for methyltransferases.
Topics: Adenosine; Aminohydrolases; Animals; Aspergillus; Brain; Chromatography, Ion Exchange; Chromatography, Thin Layer; Electrophoresis, Paper; Evaluation Studies as Topic; Guinea Pigs; Histamine; Homocysteine; Kinetics; Methods; Methyltransferases; Microchemistry; Pineal Gland; S-Adenosylmethionine; Saccharomyces cerevisiae; Serotonin; Spectrophotometry, Ultraviolet; Temperature | 1974 |
Structural and conformational analogues of L-methionine as inhibitors of the enzymatic synthesis of S-adenosyl-L-methionine. II. Aromatic amino acids.
Topics: Adenosine; Amino Acids; Animals; Electron Transport; Escherichia coli; Homocysteine; Homoserine; Hydrolysis; Liver; Malonates; Methionine; Molecular Conformation; Nitro Compounds; Phenylalanine; Rats; S-Adenosylmethionine; Structure-Activity Relationship; Transferases; Tyrosine; Valerates; Yeasts | 1974 |
Accumulation of a sterol intermediate during reaction in the presence of homocysteine with cell-free extract of yeast.
Topics: Carbon Radioisotopes; Cell-Free System; Cholestadienols; Chromatography, Gas; Chromatography, Thin Layer; Ergosterol; Homocysteine; Methyltransferases; Mevalonic Acid; Oxidation-Reduction; S-Adenosylmethionine; Saccharomyces cerevisiae; Time Factors | 1974 |
Regulation of S-amino acids biosynthesis in Aspergillus nidulans. Role of cysteine and-or homocysteine as regulatory effectors.
Topics: Acetylation; Amino Acids; Aspergillus nidulans; Carboxy-Lyases; Cysteine; Genetics, Microbial; Homocysteine; Hydro-Lyases; Lyases; Molecular Biology; Mutation; S-Adenosylmethionine | 1974 |
Sai-1 mutation: saccharomyces cerevisiae: characteristics of inhibition by S-adenosylmethonine and S-adenosylhomocysteine and protection by methionine.
Topics: Adenine; Carbon Isotopes; Cell Fractionation; Enterococcus faecalis; Genetics, Microbial; Homocysteine; Methionine; Mutation; Protein Biosynthesis; RNA; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Uracil | 1972 |
[New syntheses of S-adenosyl homocysteine analogues, potential methyltransferase inhibitors].
Topics: Adenosine; Carboxy-Lyases; Chromatography, Thin Layer; Homocysteine; Mass Spectrometry; Methods; Methyltransferases; Nucleosides; S-Adenosylmethionine; Spectrum Analysis | 1972 |
[Inactivation of pyruvate-formiate lyase from Clostridium butyricum].
Topics: Alkylation; Clostridium; Ferredoxins; Formates; Homocysteine; Lyases; Oxidation-Reduction; Pyruvates; S-Adenosylmethionine | 1972 |
[Role of sulfated amino acids in the growth of Corynebacterium sepedonicum (Spieck, et Kott) Skapt. et Burkh].
Topics: Amino Acids; Chromatography, Paper; Colorimetry; Corynebacterium; Culture Media; Cystathionine; Glutathione; Homocysteine; Homocystine; Methionine; S-Adenosylmethionine; Stereoisomerism; Sulfur | 1973 |
The synthesis of taurine from sulfate. V. Regulatory modifiers of the chick liver enzyme system.
Topics: Adenosine Monophosphate; Alanine; Allosteric Regulation; Animals; Chickens; Cysteine; Ethionine; Homocysteine; Liver; Methionine; Organophosphorus Compounds; S-Adenosylmethionine; Serine; Sulfinic Acids; Sulfonic Acids; Sulfur Radioisotopes; Sulfuric Acids; Sulfurtransferases; Taurine | 1973 |
Inhibition of indolethylamine-N-methyltransferase by S-adenosylhomocysteine.
Topics: Adenosine; Animals; Binding, Competitive; Chromatography, Gel; Chromatography, Thin Layer; Dialysis; Ethylamines; Homocysteine; Indoles; Kinetics; Lung; Methyltransferases; Protein Binding; Rabbits; S-Adenosylmethionine; Serotonin; Spectrometry, Fluorescence; Time Factors | 1973 |
The binding order of substrates to phenylethanolamine N-methyltransferase.
Topics: Adenosine; Adrenal Glands; Animals; Binding, Competitive; Carbon Radioisotopes; Chlorobenzenes; Cyclopropanes; Dose-Response Relationship, Drug; Homocysteine; In Vitro Techniques; Kinetics; Norepinephrine; Phenylethanolamine N-Methyltransferase; Propylamines; Protein Binding; Rabbits; S-Adenosylmethionine | 1973 |
Methionine metabolism in mammals: synthesis of S-adenosylhomocysteine in rat tissues.
Topics: Adenosine; Animals; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Paper; Cysteine; Dithiothreitol; Glucagon; Glutathione; Growth Hormone; Homocysteine; Hydrocortisone; Isotope Labeling; Liver; Male; Methionine; Organ Specificity; Rats; S-Adenosylmethionine; Thyroxine; Tritium | 1973 |
Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 1. Modification of the amino acid portion of S-adenosylhomocysteine.
Topics: Adenosine; Adrenal Medulla; Animals; Binding Sites; Brain; Catechol O-Methyltransferase Inhibitors; Cattle; Computers; Guinea Pigs; Histamine; Homocysteine; Indoles; Kinetics; Liver; Male; Methyltransferases; Phenylethanolamine N-Methyltransferase; Pineal Gland; Protein Binding; Rats; S-Adenosylmethionine; Structure-Activity Relationship | 1974 |
Potential inhibitor of S-adenosylmethionine-dependent methyltransferases. 2. Modification of the base portion of S-adenosylhomocysteine.
Topics: Adenosine; Adrenal Medulla; Animals; Binding Sites; Brain; Catechol O-Methyltransferase Inhibitors; Cattle; Guinea Pigs; Histamine; Homocysteine; Indoles; Kinetics; Liver; Male; Methyltransferases; Phenylethanolamine N-Methyltransferase; Pineal Gland; Protein Binding; Rats; S-Adenosylmethionine; Structure-Activity Relationship | 1974 |
The isolation of N 5 -methyltetrahydrofolate-homocysteine transmethylase from bovine brain.
Topics: Ammonium Sulfate; Animals; Brain; Carbon Isotopes; Cattle; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Disc; Flavin-Adenine Dinucleotide; Folic Acid; Homocysteine; Kidney; Liver; Methyltransferases; Organ Specificity; Protamines; S-Adenosylmethionine; Spectrophotometry | 1972 |
An assay for N 5 -methyltetrahydrofolate-homocysteine transmethylase activity using instant thin-layer chromatography.
Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Folic Acid; Formaldehyde; Homocysteine; Kidney; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine | 1972 |
Modification of pigmentation and cell-wall structure of Rhodotorula aurantiaca by culture in the presence of sulfur amino acids.
Topics: Acetone; Carbohydrates; Carotenoids; Cell Aggregation; Cell Fractionation; Cell Wall; Culture Media; Glycoside Hydrolases; Homocysteine; Lipids; Methionine; Mitosporic Fungi; Phosphorus; Pigmentation; Polysaccharides; Proteins; S-Adenosylmethionine; Snails; Solvents; Spectrum Analysis; Spheroplasts | 1972 |
Isolation of a cobalamin containing 5-methyltetrahydrofolate-homocysteine transmethylase from mammalian kidney.
Topics: Ammonium Sulfate; Animals; Calcium Phosphates; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Drug Stability; Flavin-Adenine Dinucleotide; Folic Acid; Homocysteine; Kidney; Methods; Methyltransferases; Protamines; S-Adenosylmethionine; Spectrophotometry; Sulfuric Acids; Swine; Ultraviolet Rays; Vitamin B 12 | 1971 |
Mechanism of mammalian cobalamin-dependent methionine biosynthesis.
Topics: Alkylation; Animals; Carbon Isotopes; Darkness; Dithiothreitol; Electrophoresis, Disc; Enzyme Activation; Flavin Mononucleotide; Folic Acid; Homocysteine; Hydroxocobalamin; Iodides; Kidney; Kinetics; Light; Mathematics; Mercaptoethanol; Methionine; Methylation; Methyltransferases; Models, Biological; Models, Chemical; Oxidation-Reduction; Radiation Effects; S-Adenosylmethionine; Swine; Tritium | 1971 |
Oxidative deamination of sulfur amino acids by bacterial and snake venom L-amino acid oxidase.
Topics: Adenosine; Alanine; Amino Acid Oxidoreductases; Animals; Catalase; Cattle; Chromatography, Thin Layer; Cysteine; Cystine; Homocysteine; Homocystine; Hydrogen-Ion Concentration; Kinetics; Liver; Methionine; Models, Biological; Models, Structural; Oxygen Consumption; Proteus; S-Adenosylmethionine; Snakes; Species Specificity; Sulfides; Sulfur; Venoms | 1971 |
Mutation of Saccharomyces cerevisiae preventing uptake of S-adenosylmethionine.
Topics: Adenine; Carbon Isotopes; Colorimetry; Crosses, Genetic; Culture Media; Cysteine; Genetics, Microbial; Homocysteine; Methionine; Mutation; Nucleosides; S-Adenosylmethionine; Saccharomyces; Serine; Threonine | 1971 |
Inhibition of transmethylations of biogenic amines by S-adenosylhomocysteine. Enhancement of transmethylation by adenosylhomocysteinase.
Topics: Adrenal Glands; Animals; Brain; Carbon Isotopes; Catechols; Epinephrine; Homocysteine; Hydrolases; Indoles; Methylation; Methyltransferases; Nucleosides; Rabbits; Rats; S-Adenosylmethionine | 1971 |
Catabolism of betaine and its relationship to cobalamin overproduction.
Topics: Betaine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Choline; Coenzyme A; Glycine; Homocysteine; Methionine; Methylation; Nucleosides; Porphyrins; Pseudomonas; S-Adenosylmethionine; Succinates; Sucrose; Vitamin B 12 | 1971 |
Activation and inactivation of striatal tyrosine hydroxylase: the effects of pH, ATP and cyclic AMP, S-adenosylmethionine and S-adenosylhomocysteine.
Topics: Adenosine Triphosphate; Animals; Corpus Striatum; Cyclic AMP; Enzyme Activation; Haloperidol; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tyrosine 3-Monooxygenase | 1983 |
Tropolone antagonism of the L-dopa-induced elevation of S-adenosylhomocysteine: S-adenosylmethionine ratio but not depletion of adrenaline in rat hypothalamus.
Topics: Animals; Catechol O-Methyltransferase Inhibitors; Epinephrine; Homocysteine; Hypothalamus; Levodopa; Male; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tropolone | 1984 |
Evidence that the inhibitory effect of adenosine, but not cordycepin, on the methylation of nuclear RNA is mediated by S-adenosylhomocysteine hydrolase.
Topics: Adenosine; Adenosylhomocysteinase; Adult; Animals; Cell Nucleus; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Leukemia L1210; Methylation; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Effect of inhibitors of transmethylation on histamine release from human basophils.
Topics: Adenine; Adenosine; Basophils; Calcimycin; Histamine Release; Homocysteine; Humans; Immunoglobulin E; In Vitro Techniques; Methylation; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1981 |
Inhibition of IgE-mediated histamine release from rat basophilic leukemia cells and rat mast cells by inhibitors of transmethylation.
Topics: Adenine; Adenosine; Animals; Basophils; Female; Histamine Release; Homocysteine; Immunoglobulin E; Leukemia; Mast Cells; Methylation; Mice; Rabbits; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1981 |
Effect of inhibitors of methylation on early and late interferon synthesis in bovine kidney cell cultures.
Topics: Adenine; Adenosine; Animals; Cattle; Cells, Cultured; Cycloheximide; Cycloleucine; Homocysteine; Interferons; Methylation; Newcastle disease virus; Poly I-C; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Increase in S-adenosylhomocysteine concentration in interferon-treated HeLa cells and inhibition of methylation of vesicular stomatitis virus mRNA.
Topics: Chromatography, High Pressure Liquid; HeLa Cells; Homocysteine; Humans; Interferons; Methylation; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Vesicular stomatitis Indiana virus | 1983 |
Fragile X expression is decreased by 5-azacytidine and S-adenosylhomocysteine.
Topics: Azacitidine; Cell Line; Culture Media; DNA; Dose-Response Relationship, Drug; Floxuridine; Fragile X Syndrome; Homocysteine; Humans; Karyotyping; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Chromosome Aberrations | 1983 |
Modulation by S-adenosyl-methionine and S-adenosyl-homocysteine of the human leucocytes histamine release.
Topics: Allergens; Cromolyn Sodium; Histamine Release; Homocysteine; Humans; Leukocytes; S-Adenosylhomocysteine; S-Adenosylmethionine; Theophylline | 1984 |
Microsomal phosphatidylethanolamine methyltransferase: effect of altered S-adenosylmethionine-S-adenosylhomocysteine ratios in rat liver.
Topics: Animals; Bromobenzenes; Diacylglycerol Cholinephosphotransferase; Female; Homocysteine; Liver; Methyltransferases; Microsomes, Liver; Phosphatidylethanolamine N-Methyltransferase; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Starvation | 1981 |
Transmethylation reactions regulate affinity and functional activity of chemotactic factor receptors on macrophages.
Topics: Adenosine; Animals; Arachidonic Acid; Arachidonic Acids; Cell Membrane; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Guinea Pigs; Homocysteine; Isoproterenol; Kinetics; Methylation; Receptors, Cell Surface; Receptors, Formyl Peptide; S-Adenosylmethionine; Superoxides; Theophylline | 1982 |
Reduced availability of endogenously synthesized methionine for S-adenosylmethionine formation in methionine-dependent cancer cells.
Topics: Cell Division; Cell Line; Cell Transformation, Viral; Homocysteine; Humans; Methionine; Neoplasms, Experimental; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1982 |
The effects of S-adenosylhomocysteine and S-adenosylmethionine on some purine- and pyrimidine-metabolizing systems.
Topics: 5'-Nucleotidase; Adenosine Deaminase Inhibitors; Adenylate Kinase; AMP Deaminase; Homocysteine; Nucleoside-Phosphate Kinase; Nucleotidases; Purine-Nucleoside Phosphorylase; Purines; Pyrimidines; S-Adenosylhomocysteine; S-Adenosylmethionine | 1982 |
Inhibition of rat brain microsomal Na+,K+-ATPase by S-adenosylmethionine.
Topics: Animals; Brain; Homocysteine; Lipid Metabolism; Methylation; Microsomes; Rats; S-Adenosylmethionine; Sodium-Potassium-Exchanging ATPase; Tubercidin | 1984 |
The effects of S-adenosyl methionine (AdoMet) and its analogues on the control of transcription and translation in vitro of the mRNA products of two cytoplasmic polyhedrosis viruses.
Topics: Adenosine; Cell-Free System; DNA-Directed RNA Polymerases; Ethionine; Homocysteine; Insect Viruses; Kinetics; Plants; Protein Biosynthesis; Ribonucleotides; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity; Transcription, Genetic; Triticum | 1983 |
Synthesis of bridged catechol-homocysteine derivatives as potential inhibitors of catechol O-methyltransferase.
Topics: Animals; Catechol O-Methyltransferase Inhibitors; Catechols; Chemical Phenomena; Chemistry; Homocysteine; In Vitro Techniques; Rats; S-Adenosylmethionine | 1984 |
Elevated overall rates of transmethylation in cell lines from diverse human tumors.
Topics: Adenosylhomocysteinase; Cell Line; Homocysteine; Humans; Hydrolases; Methionine; Methylation; Neoplasms, Experimental; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1984 |
Brain methylation and epileptogenesis: the case of methionine sulfoximine.
Topics: Adenosine; Animals; Brain; Epilepsy; Histamine; Homocysteine; Methionine; Methionine Sulfoximine; Methylation; Methylhistamines; Mice; Nerve Tissue Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Inhibition of protein carboxyl methylation by S-adenosyl-L-homocysteine in intact erythrocytes. Physiological consequences.
Topics: Adenosine; Aspartic Acid; Erythrocyte Membrane; Erythrocytes; Homocysteine; Humans; Membrane Proteins; Methionine; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Effect of 2'-deoxycoformycin infusion on S-adenosylhomocysteine hydrolase and the amount of S-adenosylhomocysteine and related compounds in tissues of mice.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosylhomocysteinase; Animals; Coformycin; Deoxyadenosines; Homocysteine; Hydrolases; Infusions, Parenteral; Jejunum; Kidney; Kinetics; Liver; Mice; Nucleoside Deaminases; Organ Specificity; Pentostatin; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine | 1983 |
Effect of methotrexate with 5-methyltetrahydrofolate rescue and dietary homocystine on survival of leukemic mice and on concentrations of liver adenosylamino acids.
Topics: Animals; Diet; Homocysteine; Homocystine; Kinetics; Leukemia L1210; Leukemia L5178; Leukemia, Experimental; Liver; Male; Methotrexate; Mice; Mice, Inbred DBA; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 1983 |
Methylation of phospholipids in microsomes of the rat aorta.
Topics: Animals; Aorta, Thoracic; Chromatography, Thin Layer; Fluorescence Polarization; Homocysteine; Male; Methylation; Microsomes; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Trypsin; Type C Phospholipases | 1983 |
Altered methionine metabolism occurs in all members of a set of diverse human tumor cell lines.
Topics: Cell Line; Homocysteine; Humans; Methionine; Models, Biological; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Methionine metabolism in mammals. Distribution of homocysteine between competing pathways.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosine Deaminase; Adenosylhomocysteinase; Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Homocysteine; Hydrolases; In Vitro Techniques; Liver; Male; Methionine; Methyltransferases; Models, Biological; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Tissue levels of S-adenosylmethionine and S-adenosylhomocysteine in rats fed methyl-deficient, amino acid-defined diets for one to five weeks.
Topics: Animals; Body Weight; Choline Deficiency; Diet; Folic Acid Deficiency; Homocysteine; Kinetics; Liver; Lung; Male; Methionine; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Testis; Tissue Distribution; Vitamin B 12 Deficiency | 1983 |
Measurements of S-adenosylmethionine and L-homocysteine metabolism in cultured human lymphoid cells.
Topics: Cells, Cultured; Homocysteine; Humans; Lymphocytes; Mathematics; Methionine; S-Adenosylmethionine; Time Factors | 1983 |
Perturbations in S-adenosylhomocysteine and S-adenosylmethionine metabolism: effects on transmethylation.
Topics: Adenosine; Adenosylhomocysteinase; Cell Line; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Lymphocytes; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 1980 |
The regional concentrations of S-adenosyl-L-methionine, S-adenosyl-L-homocysteine, and adenosine in rat brain.
Topics: Adenosine; Aging; Animals; Brain; Brain Chemistry; Homocysteine; Male; Pineal Gland; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tissue Distribution | 1982 |
Inactivation of S-adenosylhomocysteine hydrolase by 9-beta-D-arabinofuranosyladenine in intact cells.
Topics: Adenosylhomocysteinase; Animals; Biological Transport; Cells, Cultured; Chromatography, High Pressure Liquid; Enzyme Activation; Homocysteine; Humans; Hydrolases; Kinetics; Leukemia, Experimental; Liver; Mice; Plasmacytoma; S-Adenosylhomocysteine; S-Adenosylmethionine; Vidarabine | 1982 |
Methionine metabolism in mammals: concentration of metabolites in rat tissues.
Topics: Amino Acids, Sulfur; Animals; Cysteine; Cystine; Dietary Proteins; Homeostasis; Homocysteine; Male; Methionine; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfhydryl Compounds; Tissue Distribution | 1982 |
Effect of 9-beta-D-arabinofuranosyladenine and erythro-9-(2-hydroxy-3-nonyl) adenine on the metabolism of S-adenosylhomocysteine, S-adenosylmethionine, and adenosine in rat liver.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Female; Homocysteine; Hydrolases; Liver; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Vidarabine | 1982 |
Decreased in vivo protein and phospholipid methylation after in vivo elevation of brain S-adenosyl-homocysteine.
Topics: Adenosine; Animals; Brain; Homocysteine; Male; Methylation; Mice; Nerve Tissue Proteins; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Decreased transmethylation of biogenic amines after in vivo elevation of brain S-adenosyl-l-homocysteine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Biogenic Amines; Brain; Catechol O-Methyltransferase Inhibitors; Histamine; Histamine N-Methyltransferase; Homocysteine; Hydrolases; Liver; Male; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Stimulation of transcription by S-adenosyl-L-homocysteine and virion-encapsidated methyl donor in spring viraemia of carp virus.
Topics: Animals; Capsid; Carps; Homocysteine; Kinetics; Methylation; Rhabdoviridae; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcription, Genetic; Virion | 1981 |
Microsomal phosphatidylethanolamine methyltransferase: inhibition by S-adenosylhomocysteine.
Topics: Animals; Female; Guinea Pigs; Homocysteine; Kinetics; Methyltransferases; Mice; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rabbits; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Phosphatidylethanolamine methylation in membranes from rat cerebral cortex : effect of exogenous phospholipids and S-adenosylhomocysteine.
Topics: Animals; Cerebral Cortex; Homocysteine; In Vitro Techniques; Membranes; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phospholipids; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
[A new method for determination of adenosylmethionine, adenosyl-homocysteine and decarboxylated adenosylmethionine].
Topics: Animals; Chromatography, High Pressure Liquid; Homocysteine; Liver; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Inhibition by S-adenosyl-L-homocysteine of dopamine dependent adenylate cyclase in rat retina.
Topics: Adenylyl Cyclase Inhibitors; Animals; Dopamine; Homocysteine; Male; Rats; Retina; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
S-Adenosylmethionine and S-adenosylhomocystein metabolism in isolated rat liver. Effects of L-methionine, L-homocystein, and adenosine.
Topics: Adenosine; Animals; DNA; Female; Histones; Homocysteine; Kinetics; Liver; Methionine; Perfusion; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Determination of S-adenosylmethionine and S-adenosylhomocysteine in nuclei isolated from sea urchin embryos during early development.
Topics: Animals; Cell Nucleus; Embryo, Nonmammalian; Homocysteine; S-Adenosylhomocysteine; S-Adenosylmethionine; Sea Urchins | 1980 |
Enhancement of depolarization-dependent release of norepinephrine by an inhibitor of S-adenosylmethionine-dependent transmethylations.
Topics: Adrenal Gland Neoplasms; Animals; Carbachol; Cell Line; Clone Cells; Homocysteine; Kinetics; Norepinephrine; Pheochromocytoma; Potassium; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1980 |
Carbon tetrachloride-induced hepatic injury is associated with global DNA hypomethylation and homocysteinemia: effect of S-adenosylmethionine treatment.
Topics: Animals; Carbon Tetrachloride; Cystathionine; DNA; Folic Acid; Homocysteine; Liver; Liver Cirrhosis, Experimental; Male; Methionine; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1995 |
Homocysteine enhances the inhibitory effect of extracellular adenosine on the synthesis of proteins in isolated rat hepatocytes.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cell Survival; Cells, Cultured; Drug Synergism; Homocysteine; Hydrolases; Inosine; Kinetics; Liver; Male; Protein Biosynthesis; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 1995 |
Hyperhomocysteinemia in premature arterial disease: examination of cystathionine beta-synthase alleles at the molecular level.
Topics: Alleles; Arterial Occlusive Diseases; Base Sequence; Blotting, Western; Cell Line; Cloning, Molecular; Cystathionine beta-Synthase; DNA, Complementary; Enzyme Activation; Female; Homocysteine; Humans; Molecular Sequence Data; Polymorphism, Genetic; S-Adenosylmethionine | 1995 |
Prevention of neural tube defects by and toxicity of L-homocysteine in cultured postimplantation rat embryos.
Topics: Adenosylhomocysteinase; Animals; Catalase; Copper; Copper Sulfate; Culture Techniques; Drug Interactions; Embryonic and Fetal Development; Embryonic Development; Female; Homocysteine; Homocystine; Hydrolases; Methionine; Neural Tube Defects; Oxidation-Reduction; Pregnancy; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Stereoisomerism; Teratogens; Vitamin B 12 | 1994 |
Mechanism of erythrocyte accumulation of methylation inhibitor S-adenosylhomocysteine in uremia.
Topics: Adenosine; Adenosylhomocysteinase; Adult; Aspartate Aminotransferases; Erythrocytes; Female; Homocysteine; Humans; Hydrolases; Male; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Uremia | 1995 |
Expression of human cystathionine beta-synthase in Escherichia coli: purification and characterization.
Topics: Amino Acid Sequence; beta-Galactosidase; Chromatography, DEAE-Cellulose; Cystathionine beta-Synthase; Enzyme Activation; Escherichia coli; Factor Xa; Homocysteine; Humans; Molecular Sequence Data; Recombinant Proteins; S-Adenosylmethionine; Serine; Spectrophotometry | 1994 |
Methylation in fertilised and parthenogenetic preimplantation mouse embryos.
Topics: Animals; DNA Modification Methylases; Embryo, Mammalian; Embryonic Development; Female; Fertilization; Genomic Imprinting; Homocysteine; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Parthenogenesis; Pregnancy; S-Adenosylmethionine | 1994 |
Effects of ageing on folate metabolism in rats fed a long-term folate deficient diet.
Topics: Aging; Animals; Folic Acid; Folic Acid Deficiency; Homocysteine; Liver; Male; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1994 |
Folate-deficiency-induced homocysteinaemia in rats: disruption of S-adenosylmethionine's co-ordinate regulation of homocysteine metabolism.
Topics: Animals; Ethionine; Folic Acid Deficiency; Homocysteine; Liver; Male; Methylation; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1994 |
Nitrous oxide inactivation of cobalamin-dependent methionine synthase from Escherichia coli: characterization of the damage to the enzyme and prosthetic group.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Binding Sites; Electrochemistry; Escherichia coli; Homocysteine; Methionine; Molecular Sequence Data; Nitrous Oxide; Oxidation-Reduction; Peptide Fragments; Peptide Mapping; S-Adenosylmethionine; Tetrahydrofolates; Trypsin; Vitamin B 12 | 1994 |
Vitamin B-6 deficiency vs folate deficiency: comparison of responses to methionine loading in rats.
Topics: Animals; Folic Acid Deficiency; Homocysteine; Kinetics; Liver; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Vitamin B 6 Deficiency | 1994 |
Methionine synthase inactivation by nitrous oxide during methionine loading of normal human fibroblasts. Homocysteine remethylation as determinant of enzyme inactivation and homocysteine export.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Division; Cell Line; Enzyme Activation; Extracellular Space; Fetus; Fibroblasts; Folic Acid; Homocysteine; Humans; Infant; Lung; Male; Methionine; Methylation; Nitrous Oxide; S-Adenosylmethionine | 1993 |
Assignment of enzymatic function to specific protein regions of cobalamin-dependent methionine synthase from Escherichia coli.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Binding Sites; Catalysis; Escherichia coli; Homocysteine; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1993 |
At least four regulatory genes control sulphur metabolite repression in Aspergillus nidulans.
Topics: Arylsulfatases; Aspergillus nidulans; Carbon-Oxygen Lyases; Chromosome Mapping; Chromosomes, Fungal; Crosses, Genetic; Cysteine Synthase; Genes, Fungal; Genes, Regulator; Genes, Suppressor; Genetic Linkage; Homocysteine; Lyases; Methionine; Multienzyme Complexes; S-Adenosylmethionine; Saccharomyces cerevisiae Proteins; Sulfate Adenylyltransferase; Sulfur | 1993 |
Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Administration, Oral; Analysis of Variance; Animal Feed; Animals; Apoptosis; Cell Division; Deoxyuracil Nucleotides; Ethanol; Folic Acid; Homocysteine; Liver; Male; Methionine; Proliferating Cell Nuclear Antigen; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Thymine Nucleotides | 1996 |
Low whole-blood S-adenosylmethionine and correlation between 5-methyltetrahydrofolate and homocysteine in coronary artery disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Case-Control Studies; Cohort Studies; Coronary Disease; Erythrocytes; Female; Follow-Up Studies; Homocysteine; Humans; Isoenzymes; Lymphocytes; Male; Methionine Adenosyltransferase; Methylation; Middle Aged; Risk Factors; S-Adenosylmethionine; Tetrahydrofolates | 1996 |
Effects on transmethylation by high-dose 6-mercaptopurine and methotrexate infusions during consolidation treatment of acute lymphoblastic leukemia.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Erythrocytes; Homocysteine; Humans; Mercaptopurine; Methionine; Methotrexate; Methylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purine Nucleotides; S-Adenosylhomocysteine; S-Adenosylmethionine | 1996 |
Effect of methionine loading on 5-methyltetrahydrofolate, S-adenosylmethionine and S-adenosylhomocysteine in plasma of healthy humans.
Topics: Adult; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Kinetics; Male; Methionine; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 1996 |
Apoptosis and transmethylation metabolites in HL-60 cells.
Topics: Adenosine; Apoptosis; DNA; DNA Fragmentation; Enzyme Inhibitors; HL-60 Cells; Homocysteine; Humans; Methylation; Methyltransferases; Nucleic Acid Synthesis Inhibitors; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1996 |
Effect of L-Dopa and the catechol-O-methyltransferase inhibitor Ro 41-0960 on sulfur amino acid metabolites in rats.
Topics: Animals; Benzophenones; Brain; Catechol O-Methyltransferase Inhibitors; Cerebellum; Cerebral Cortex; Corpus Striatum; Enzyme Inhibitors; Hippocampus; Homocysteine; Kidney; Levodopa; Liver; Male; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 1997 |
Cobalamin-dependent methionine synthase is a modular protein with distinct regions for binding homocysteine, methyltetrahydrofolate, cobalamin, and adenosylmethionine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Binding Sites; Escherichia coli; Homocysteine; Methylation; Protein Binding; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1997 |
Influence of oral S-adenosylmethionine on plasma 5-methyltetrahydrofolate, S-adenosylhomocysteine, homocysteine and methionine in healthy humans.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Administration, Oral; Adult; Female; Homocysteine; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases; Reference Values; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 1997 |
Nerve growth factor-specific regulation of protein methylation during neuronal differentiation of PC12 cells.
Topics: Adenosine; Animals; Cell Differentiation; Cell-Free System; DNA Methylation; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Homocysteine; Kinetics; Methionine; Methylation; Nerve Growth Factors; Nerve Tissue Proteins; Neurites; Neurons; PC12 Cells; Protein Processing, Post-Translational; Rats; S-Adenosylmethionine; Signal Transduction; Tritium | 1997 |
Evidence for disturbed S-adenosylmethionine : S-adenosylhomocysteine ratio in patients with end-stage renal failure: a cause for disturbed methylation reactions?
Topics: Adult; Aged; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylation; Middle Aged; Models, Biological; Renal Dialysis; S-Adenosylhomocysteine; S-Adenosylmethionine | 1998 |
Purification of soluble cytochrome b5 as a component of the reductive activation of porcine methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Bacterial Proteins; Cytochromes b5; Cytoplasm; Electron Transport; Enzyme Activation; Erythrocytes; Homocysteine; Liver; Mass Spectrometry; Methemoglobin; Microsomes; NADH, NADPH Oxidoreductases; NADP; NADPH-Ferrihemoprotein Reductase; S-Adenosylmethionine; Solubility; Spectrophotometry; Swine | 1998 |
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
Topics: Amino Acid Metabolism, Inborn Errors; Benzoic Acid; Brain Diseases; Choline; Coma; Female; Glycine; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methionine; Methylation; Phosphatidylcholines; S-Adenosylmethionine; Seizures; Serine; Tetrahydrofolates | 1998 |
Deletion of the regulatory domain in the pyridoxal phosphate-dependent heme protein cystathionine beta-synthase alleviates the defect observed in a catalytic site mutant.
Topics: Catalytic Domain; Cystathionine beta-Synthase; Hemeproteins; Homocysteine; Homocystinuria; Humans; Models, Molecular; Protein Structure, Tertiary; Pyridoxal Phosphate; S-Adenosylmethionine; Sequence Deletion; Suppression, Genetic | 1999 |
Interrelations between plasma homocysteine and intracellular S-adenosylhomocysteine.
Topics: Adult; Aged; Animals; Case-Control Studies; Chromatography, High Pressure Liquid; Erythrocytes; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Tissue Distribution; Vascular Diseases | 2000 |
Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy.
Topics: Animals; Betaine; Homocysteine; Hyperlipidemias; Liver; Niacin; Rats; S-Adenosylmethionine | 2000 |
Disturbed ratio of erythrocyte and plasma S-adenosylmethionine/S-adenosylhomocysteine in peripheral arterial occlusive disease.
Topics: Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Erythrocytes; Female; Hematocrit; Homocysteine; Humans; Kidney; Male; Middle Aged; Odds Ratio; Reference Values; S-Adenosylhomocysteine; S-Adenosylmethionine | 2001 |
Occurrence of transsulfuration in synthesis of L-homocysteine in an extremely thermophilic bacterium, Thermus thermophilus HB8.
Topics: Culture Media; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Cysteine Synthase; Gene Expression Regulation, Bacterial; Homocysteine; Lyases; Methionine; S-Adenosylmethionine; Sulfur; Temperature; Thermus thermophilus | 2001 |
Homocysteine metabolism in children with Down syndrome: in vitro modulation.
Topics: Adenosine; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cystathionine beta-Synthase; Cysteine; DNA Methylation; Down Syndrome; Glutathione; Homocysteine; Humans; Leucovorin; Lymphocytes; Methionine; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Superoxide Dismutase; Thymidine; Vitamin B 12 | 2001 |
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.
Topics: Animals; Aorta; Brain; Chronic Disease; Cystathionine beta-Synthase; Disease Models, Animal; Endothelium, Vascular; Folic Acid; Food, Fortified; Heterozygote; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine; Thrombomodulin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2001 |
Blood determinations of S-adenosylmethionine, S-adenosylhomocysteine, and homocysteine: correlations with diet.
Topics: Body Mass Index; Diet; Dietary Fats; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Neoplasms; Pyridoxine; Reference Values; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine | 2001 |
A new caffeine biosynthetic pathway in tea leaves: utilisation of adenosine released from the S-adenosyl-L-methionine cycle.
Topics: Adenosine; Adenosylhomocysteinase; Caffeine; Carbon Dioxide; Cell Extracts; Chloroplasts; Homocysteine; Hydrolases; Methionine Adenosyltransferase; Methylation; Plant Leaves; S-Adenosylhomocysteine; S-Adenosylmethionine; Tea; Theobromine | 2001 |
Decrease of methionine and S-adenosylmethionine and increase of homocysteine in treated patients with Parkinson's disease.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Cardiovascular Diseases; Dopa Decarboxylase; Down-Regulation; Drug Interactions; Enzyme Inhibitors; Female; Homocysteine; Humans; Levodopa; Male; Methionine; Middle Aged; Parkinson Disease; S-Adenosylmethionine; Up-Regulation | 2001 |
The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule.
Topics: 4-Butyrolactone; Bacterial Proteins; Carbon-Sulfur Lyases; Cell Extracts; Cell-Free System; Dialysis; Genomics; Homocysteine; Homoserine; Lactones; Luminescent Measurements; Mass Spectrometry; Multigene Family; S-Adenosylmethionine; Salmonella typhimurium; Signal Transduction; Vibrio | 2001 |
Increasing levels of dietary homocystine with carotid endarterectomy produced proportionate increases in plasma homocysteine and intimal hyperplasia.
Topics: Animals; Carotid Arteries; Cystathionine beta-Synthase; Endarterectomy, Carotid; Homocysteine; Homocystine; Hyperplasia; Liver; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Rats; Rats, Sprague-Dawley; Recurrence; S-Adenosylhomocysteine; S-Adenosylmethionine; Tunica Intima | 2001 |
Methylation is involved in the Ustilago maydis mating response.
Topics: Cyclic AMP; Ethionine; Homocysteine; Methionine; Methylation; Methyltransferases; Mutation; Pheromones; Plants; Reproduction; S-Adenosylmethionine; Signal Transduction; Ustilago | 2001 |
COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk.
Topics: Breast Neoplasms; Case-Control Studies; Catechol O-Methyltransferase; Cysteine; Estrogens, Catechol; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylation; Micronutrients; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyridoxal Phosphate; Risk Factors; S-Adenosylmethionine; Vitamin B 12 | 2001 |
Dietary betaine accumulates in the liver and intestinal tissue and stabilizes the intestinal epithelial structure in healthy and coccidia-infected broiler chicks.
Topics: Animals; Betaine; Chickens; Chromatography, High Pressure Liquid; Coccidia; Coccidiosis; Epithelium; Female; Gastrointestinal Agents; Homocysteine; Intestines; Jejunum; Liver; Male; Models, Biological; S-Adenosylmethionine | 2001 |
Plasma S-adenosylhomocysteine is a more sensitive indicator of cardiovascular disease than plasma homocysteine.
Topics: Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Sensitivity and Specificity; Vitamin B 12 | 2001 |
Abnormal cobalamin-dependent transmethylation in AIDS-associated myelopathy.
Topics: Adult; Female; Glutathione; HIV Infections; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged; S-Adenosylmethionine; Spinal Cord Diseases; Vitamin B 12 | 2002 |
Tissue levels of S-adenosylhomocysteine in the rat kidney: effects of ischemia and homocysteine.
Topics: Adenosine; Animals; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Ischemia; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2002 |
High homocysteine and thrombosis without connective tissue disorders are associated with a novel class of cystathionine beta-synthase (CBS) mutations.
Topics: Adult; Animals; Cell Line; Connective Tissue; Cricetinae; Cricetulus; Cystathionine beta-Synthase; DNA Mutational Analysis; Enzyme Stability; Escherichia coli; Female; Fibroblasts; Homocysteine; Humans; Male; Middle Aged; Mutation, Missense; Phenotype; S-Adenosylmethionine; Thrombosis | 2002 |
The effect of troglitazone on plasma homocysteine, hepatic and red blood cell S-adenosyl methionine, and S-adenosyl homocysteine and enzymes in homocysteine metabolism in Zucker rats.
Topics: Animals; Chromans; Cystathionine beta-Synthase; Erythrocytes; Female; Homocysteine; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Methylenetetrahydrofolate Reductase (NADPH2); Obesity; Oxidoreductases Acting on CH-NH Group Donors; Rats; Rats, Zucker; S-Adenosylhomocysteine; S-Adenosylmethionine; Thiazoles; Thiazolidinediones; Thinness; Troglitazone | 2002 |
S-adenosylhomocysteine, but not homocysteine, is toxic to yeast lacking cystathionine beta-synthase.
Topics: Chromatography, High Pressure Liquid; Culture Media; Cystathionine beta-Synthase; Homocysteine; Homocystinuria; Humans; S-Adenosylhomocysteine; S-Adenosylmethionine; Yeasts | 2002 |
Brain hydrogen sulfide is severely decreased in Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acids; Blotting, Western; Brain; Cysteine; Dose-Response Relationship, Drug; Homocysteine; Humans; Hydrogen Sulfide; S-Adenosylmethionine | 2002 |
Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses.
Topics: Animals; Cell Line; Cytoplasm; Deoxyribonucleotides; DNA; Folic Acid; Glycine; Glycine Hydroxymethyltransferase; Homocysteine; Humans; Methylation; S-Adenosylmethionine; Tetrahydrofolates; Thymidine Monophosphate | 2002 |
In the cystathionine beta-synthase knockout mouse, elevations in total plasma homocysteine increase tissue S-adenosylhomocysteine, but responses of S-adenosylmethionine and DNA methylation are tissue specific.
Topics: Animals; Base Sequence; Cystathionine beta-Synthase; DNA; DNA Methylation; DNA Primers; Genotype; Homocysteine; Mice; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine | 2002 |
Acute valproate administration impairs methionine metabolism in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Anticonvulsants; Betaine-Homocysteine S-Methyltransferase; Female; Folic Acid; Glutathione; Glutathione Disulfide; Homocysteine; Liver; Methionine; Methionine Adenosyltransferase; Methyltransferases; Models, Animal; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Teratogens; Valproic Acid; Vitamin B 6 | 2002 |
Remethylation and transsulfuration of methionine in cirrhosis: studies with L-[H3-methyl-1-C]methionine.
Topics: Adult; Carbon Isotopes; Homocysteine; Humans; Kinetics; Liver Cirrhosis, Alcoholic; Male; Methionine; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tritium | 2002 |
S-homoadenosyl-L-cysteine and S-homoadenosyl-L-homocysteine. Synthesis and binding studies of hon-hydrolyzed substrate analogues with S-adenosyl-L-homocysteine hydrolase.
Topics: Adenosylhomocysteinase; Cysteine; Enzyme Inhibitors; Homocysteine; Humans; Hydrolases; Kinetics; Placenta; Protein Binding; S-Adenosylmethionine | 2002 |
Multiple aspects of homocysteine neurotoxicity: glutamate excitotoxicity, kinase hyperactivation and DNA damage.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; DNA Damage; Dose-Response Relationship, Drug; Enzyme Activation; Glutamic Acid; Homocysteine; Mice; Mitogen-Activated Protein Kinases; Neurons; Neurotoxins; Oxidative Stress; Phosphorylation; Protein Kinases; Receptors, N-Methyl-D-Aspartate; S-Adenosylmethionine; tau Proteins | 2002 |
Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism.
Topics: Anemia; Anemia, Pernicious; Cysteine; Dipeptides; Folic Acid; Glutathione; Homocysteine; Humans; Memory Disorders; Methionine; Movement Disorders; Nervous System Diseases; Retrospective Studies; S-Adenosylmethionine; Sensation Disorders; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
The effect of dietary folate on genomic and p53-specific DNA methylation in rat colon.
Topics: Animals; Body Weight; Colon; Dietary Supplements; DNA Methylation; Folic Acid; Genome; Hemoglobins; Homocysteine; Rats; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Tumor Suppressor Protein p53 | 2003 |
Anthocyanin administration elevates plasma homocysteine in rats.
Topics: Animals; Anthocyanins; Female; Homocysteine; Kidney; Liver; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2002 |
Factors modulating conformational equilibria in large modular proteins: a case study with cobalamin-dependent methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Substitution; Catalysis; Escherichia coli; Escherichia coli Proteins; Homocysteine; Methionine; Methylation; Mutation, Missense; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity; Temperature; Tetrahydrofolates; Vitamin B 12 | 2003 |
Molecular dissection of the S-adenosylmethionine-binding site of phosphatidylethanolamine N-methyltransferase.
Topics: Amino Acid Sequence; Animals; Base Sequence; Chlorocebus aethiops; Computational Biology; Conserved Sequence; COS Cells; DNA Primers; Homocysteine; Humans; Hydrolysis; Methylation; Methyltransferases; Mice; Models, Molecular; Mutagenesis, Site-Directed; Phosphatidylethanolamine N-Methyltransferase; Polymerase Chain Reaction; Protein Conformation; Recombinant Proteins; S-Adenosylmethionine; Transfection | 2003 |
Regulation of S-adenosylmethionine levels in Saccharomyces cerevisiae.
Topics: Cell Division; Cysteine; Formates; Gene Deletion; Gene Expression Regulation, Fungal; Genotype; Glycine; Homocysteine; Microscopy, Fluorescence; Models, Biological; Mutation; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfur; Time Factors; Vacuoles | 2003 |
BIOSYNTHESIS OF METHIONINE IN SACCHAROMYCES CEREVISIAE; PARTIAL PURIFICATION AND PROPERTIES OF S-ADENOSYLMETHIONINE: HOMOCYSTEINE METHYLTRANSFERASE. ANL-6823.
Topics: Carbon Isotopes; Chromatography; Homocysteine; Homocysteine S-Methyltransferase; Metabolism; Methionine; Research; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Sulfur Isotopes; Toluene; Transferases | 1964 |
BIOSYNTHESIS OF METHIONINE IN SACCHAROMYCES CEREVISIAE. PARTIAL PURIFICATION AND PROPERTIES OF S-ADENOSYLMETHIONINE: HOMOCYSTEINE METHYLTRANSFERASE.
Topics: Amino Acids; Chromatography; Homocysteine; Homocysteine S-Methyltransferase; Methionine; Nucleosides; Research; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Transferases | 1964 |
ENZYMATIC SYNTHESIS OF THE METHYL GROUP OF METHIONINE. IX. TRANSMETHYLATION FROM S-ADENOSYLMETHIONINE AND 5-METHYLTETRAHYDROFOLATE TO 2-MERCAPTOETHANOL AND HOMOCYSTEINE.
Topics: Alkylation; Biological Assay; Carbon Isotopes; Folic Acid; Homocysteine; Kinetics; Lactobacillus; Mercaptoethanol; Methionine; Nucleosides; Research; S-Adenosylmethionine; Spectrophotometry; Sulfhydryl Compounds; Tetrahydrofolates; Transferases | 1965 |
BIOSYNTHESIS OF METHIONINE IN SACCHAROMYCES CEREVISIAE. KINETICS AND MECHANISM OF REACTION OF S-ADENOSYLMETHIONINE:HOMOCYSTEINE METHYLTRANSFERASE.
Topics: Amino Acids; Chromatography; Homocysteine; Homocysteine S-Methyltransferase; Ions; Kinetics; Mercaptoethanol; Methionine; Nucleosides; Research; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Sulfhydryl Compounds; Transferases | 1965 |
A mathematical model of the methionine cycle.
Topics: Animals; Computational Biology; Cystathionine; Homocysteine; Methionine; Models, Biological; S-Adenosylhomocysteine; S-Adenosylmethionine | 2004 |
Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status.
Topics: Antiparkinson Agents; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Methylation; Parkinson Disease; S-Adenosylmethionine; Vitamin B Complex | 2004 |
Methionine metabolism in plants: chloroplasts are autonomous for de novo methionine synthesis and can import S-adenosylmethionine from the cytosol.
Topics: Arabidopsis; Blotting, Western; Chloroplasts; Cloning, Molecular; Cytosol; Diffusion; DNA, Complementary; Dose-Response Relationship, Drug; Escherichia coli; Green Fluorescent Proteins; Homocysteine; Immunoblotting; Kinetics; Luminescent Proteins; Methionine; Mitochondria; Models, Biological; Molecular Sequence Data; Phylogeny; Pisum sativum; Plastids; Protein Isoforms; S-Adenosylmethionine; Time Factors; Vitamin B 12 | 2004 |
Levodopa elevates homocysteine: is this a problem?
Topics: Antiparkinson Agents; Brain; Homocysteine; Humans; Levodopa; Parkinson Disease; Peripheral Nervous System Diseases; S-Adenosylmethionine | 2004 |
Improved rotorod performance and hyperactivity in mice deficient in a protein repair methyltransferase.
Topics: Age Factors; Aging; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Diet, Reducing; Exploratory Behavior; Genotype; Homocysteine; Hyperkinesis; Mice; Mice, Knockout; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Rotarod Performance Test; S-Adenosylhomocysteine; S-Adenosylmethionine; Stereotyped Behavior; Survival Rate; Time Factors | 2004 |
Homocysteine clearance and methylation flux rates in health and end-stage renal disease: association with S-adenosylhomocysteine.
Topics: Adult; Aged; Case-Control Studies; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur | 2004 |
Modulation of methyl group metabolism by streptozotocin-induced diabetes and all-trans-retinoic acid.
Topics: Animals; Cystathionine beta-Synthase; Diabetes Mellitus, Experimental; Glycine N-Methyltransferase; Homocysteine; Male; Methyltransferases; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Streptozocin; Tretinoin | 2004 |
Low ratio of S-adenosylmethionine to S-adenosylhomocysteine is associated with vitamin deficiency in Brazilian pregnant women and newborns.
Topics: Adult; Birth Weight; Brazil; Female; Fetal Blood; Gestational Age; Homocysteine; Humans; Infant, Newborn; Pregnancy; ROC Curve; S-Adenosylhomocysteine; S-Adenosylmethionine; Social Class; Vitamin B 12 Deficiency | 2004 |
Bioavailability and lack of toxicity of S-adenosyl-L-methionine (SAMe) in humans.
Topics: Administration, Oral; Adult; Biological Availability; Bipolar Disorder; Female; Formaldehyde; Formates; Homocysteine; Humans; Male; S-Adenosylmethionine | 2004 |
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2004 |
S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Brain; Cell Line, Tumor; Culture Media, Serum-Free; DNA Methylation; Endopeptidases; Folic Acid Deficiency; Gene Expression; Homocysteine; Humans; Membrane Proteins; Presenilin-1; Promoter Regions, Genetic; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2005 |
Phosphatidylcholine and lysophosphatidylcholine excretion is increased in children with cystic fibrosis and is associated with plasma homocysteine, S-adenosylhomocysteine, and S-adenosylmethionine.
Topics: Case-Control Studies; Child; Choline Deficiency; Cross-Sectional Studies; Cystic Fibrosis; Diet Records; Dietary Fats; Feces; Female; Homocysteine; Humans; Intestinal Absorption; Lysophosphatidylcholines; Male; Phosphatidylcholines; S-Adenosylhomocysteine; S-Adenosylmethionine | 2005 |
Homocysteine alterations in experimental cholestasis and its subsequent cirrhosis.
Topics: Analysis of Variance; Animals; Bile Ducts; Cholestasis; Cysteine; Glutathione; Homocysteine; Ligation; Liver; Liver Cirrhosis, Biliary; Male; Methionine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 2005 |
Disturbed homocysteine and methionine cycle intermediates S-adenosylhomocysteine and S-adenosylmethionine are related to degree of renal insufficiency in type 2 diabetes.
Topics: Aged; Cystathionine; Cysteine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Folic Acid; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Male; Methionine; Methylmalonic Acid; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcobalamins; Vitamin B 12; Vitamin B 6 | 2005 |
Human embryonic stem cell methyl cycle enzyme expression: modelling epigenetic programming in assisted reproduction?
Topics: Cell Proliferation; Cells, Cultured; DNA Modification Methylases; Embryo, Mammalian; Enzymes; Epigenesis, Genetic; Folic Acid; Folic Acid Antagonists; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Methotrexate; Reproductive Techniques, Assisted; S-Adenosylmethionine; Stem Cells | 2005 |
Hepatic S-adenosylmethionine after maternal alcohol exposure on offspring rats.
Topics: Animals; Animals, Newborn; Cysteine; DNA Methylation; Drug Administration Schedule; Ethanol; Female; Homocysteine; Lactation; Liver; Male; Maternal Behavior; Nutritional Status; Pregnancy; Pregnancy, Animal; Random Allocation; Rats; Rats, Wistar; S-Adenosylmethionine | 2005 |
Maternal polymorphisms 677C-T and 1298A-C of MTHFR, and 66A-G MTRR genes: is there any relationship between polymorphisms of the folate pathway, maternal homocysteine levels, and the risk for having a child with Down syndrome?
Topics: Case-Control Studies; Down Syndrome; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Homocysteine; Humans; Infant; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Mutation; Polymorphism, Single Nucleotide; Regression Analysis; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine | 2006 |
Differential effects of dietary selenium (se) and folate on methyl metabolism in liver and colon of rats.
Topics: Animals; Colon; Deficiency Diseases; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Folic Acid; Glutathione; Glutathione Peroxidase; Glycine N-Methyltransferase; Homocysteine; Liver; Male; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Selenium | 2006 |
The 5th workshop on the assessment of adequate intake of dietary amino acids: general discussion 1.
Topics: Amino Acids; Animals; Creatine; Cysteine; Diet; Glutathione; Homocysteine; Humans; Methionine; Nutritional Requirements; S-Adenosylhomocysteine; S-Adenosylmethionine | 2006 |
Exogenous glycine partially attenuates homocysteine-induced apoptosis and membrane peroxidation in chick embryos.
Topics: Animals; Apoptosis; Brain; Brain Chemistry; Caspase 3; Caspases; Chick Embryo; Fatty Acids; Glycine; Homocysteine; Lipid Peroxides; Liver; Membranes; S-Adenosylhomocysteine; S-Adenosylmethionine | 2006 |
Suppression of methionine-induced hyperhomocysteinemia by dietary eritadenine in rats.
Topics: Adenine; Animals; Cystathionine beta-Synthase; Diet; Dose-Response Relationship, Drug; Enzyme Activation; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 2006 |
Folate, the methionine cycle, and Alzheimer's disease.
Topics: Alzheimer Disease; Brain; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Reactive Oxygen Species; S-Adenosylmethionine | 2006 |
A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism.
Topics: Betaine; Carbon; DNA Methylation; Folic Acid; Formate-Tetrahydrofolate Ligase; Homocysteine; Humans; Kinetics; Mathematics; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Molecular Biology; Nutritional Physiological Phenomena; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Polymorphism, Genetic; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2006 |
Role of S-adenosylhomocysteine hydrolase in adenosine-induced apoptosis in HepG2 cells.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosylhomocysteinase; Apoptosis; Caspase Inhibitors; Caspases; Dipyridamole; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Homocysteine; Humans; Methylation; Nucleoside Transport Proteins; Oligonucleotide Array Sequence Analysis; Pentostatin; Proto-Oncogene Proteins c-mdm2; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Dietary polyphenols may affect DNA methylation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carrier Proteins; Catechin; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cyclin-Dependent Kinase Inhibitor p16; Diet; DNA Methylation; DNA Modification Methylases; Flavonoids; Genistein; Homocysteine; Humans; Mice; MutL Protein Homolog 1; Nuclear Proteins; Phenols; Polyphenols; Promoter Regions, Genetic; Receptors, Retinoic Acid; S-Adenosylmethionine; Tumor Suppressor Protein p14ARF | 2007 |
Cysteine supplementation decreases plasma homocysteine concentration in rats fed on a low-casein diet in rats.
Topics: Animal Feed; Animals; Body Weight; Caseins; Cysteine; Dietary Supplements; Homocysteine; Liver; Male; Organ Size; Rats; Rats, Wistar; S-Adenosylmethionine | 2007 |
New insights into the regulation of methyl group and homocysteine metabolism.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Folic Acid; Glycine N-Methyltransferase; Homocysteine; Humans; Mice; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylmethionine | 2007 |
Recognition of age-damaged (R,S)-adenosyl-L-methionine by two methyltransferases in the yeast Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Animals; Arabidopsis; Caenorhabditis elegans; Drosophila melanogaster; Homocysteine; Homocysteine S-Methyltransferase; Kinetics; Methionine; Methyltransferases; Mice; Molecular Sequence Data; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Substrate Specificity | 2007 |
Increase in S-adenosylhomocysteine content and its effect on the S-adenosylhomocysteine hydrolase activity under transient high plasma homocysteine levels in rats.
Topics: Adenosylhomocysteinase; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Homocysteine; Infusions, Intravenous; Liver; Male; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Sodium Chloride | 2006 |
DNA methylation status is not impaired in treated cystathionine beta-synthase (CBS) deficient patients.
Topics: Chromatography, Liquid; Cystathionine beta-Synthase; DNA; DNA Methylation; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Analysis, DNA; Spectrometry, Mass, Electrospray Ionization | 2007 |
Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase.
Topics: Animals; Brain; Disease Models, Animal; Embryo, Mammalian; Female; Ferredoxin-NADP Reductase; Folic Acid; Heart; Homocysteine; Hyperhomocysteinemia; Kidney; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Folate status and S-adenosylmethionine/S-adenosylhomocysteine ratio in colorectal adenocarcinoma in humans.
Topics: Adenocarcinoma; Aged; Colon; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Intestinal Mucosa; Male; Nutritional Status; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
Consideration of betaine and one-carbon sources of N5-methyltetrahydrofolate for use in homocystinuria and neural tube defects.
Topics: Betaine; Dietary Supplements; Folic Acid; Homocysteine; Homocystinuria; Humans; Methionine; Methylation; Neural Tube Defects; Nutritional Physiological Phenomena; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B Complex | 2007 |
Supranormal dietary folic acid supplementation: effects on methionine metabolism in weanling rats.
Topics: Animals; Biomarkers; Dietary Supplements; DNA Methylation; Folic Acid; Homocysteine; Liver; Male; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamins; Weaning | 2007 |
Homocysteine affects cardiomyocyte viability: concentration-dependent effects on reversible flip-flop, apoptosis and necrosis.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Caspase 3; Cell Membrane; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression Regulation; Homocysteine; Membrane Fluidity; Membrane Glycoproteins; Membrane Potential, Mitochondrial; Mitochondria, Heart; Models, Biological; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Necrosis; Phospholipids; Protein Processing, Post-Translational; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells.
Topics: Cell Line, Tumor; Cytoplasm; Dose-Response Relationship, Drug; Folic Acid; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glycine Hydroxymethyltransferase; Homocysteine; Humans; Kinetics; Mitochondria; Protein Isoforms; Pyridoxine; S-Adenosylmethionine; Vitamin B 6 | 2007 |
Copper deficiency decreases plasma homocysteine in rats.
Topics: Animals; Ceruloplasmin; Copper; Glutathione; Homocysteine; Liver; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine | 2007 |
Association between decreased vitamin levels and MTHFR, MTR and MTRR gene polymorphisms as determinants for elevated total homocysteine concentrations in pregnant women.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Alleles; Analysis of Variance; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Young Adult | 2008 |
Testosterone regulation of renal cystathionine beta-synthase: implications for sex-dependent differences in plasma homocysteine levels.
Topics: Animals; Blotting, Northern; Blotting, Western; Cricetinae; Cystathionine beta-Synthase; Female; Gene Expression Regulation, Enzymologic; Glutathione; Guinea Pigs; Homocysteine; Humans; Kidney; Kidney Cortex; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Rabbits; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Sex Characteristics; Species Specificity; Testosterone | 2007 |
Priorities in the discovery of the implications of water channels in epilepsy and Duchenne muscular dystrophy.
Topics: Aquaporins; Brain; Epilepsy; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Muscular Dystrophy, Duchenne; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Homocysteine-mediated expression of SAHH, DNMTs, MBD2, and DNA hypomethylation potential pathogenic mechanism in VSMCs.
Topics: Adenosylhomocysteinase; Atherosclerosis; Base Sequence; Blotting, Western; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA-Binding Proteins; Enzyme Induction; Homocysteine; Humans; Molecular Sequence Data; Muscle, Smooth, Vascular; Polymerase Chain Reaction; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes.
Topics: Animals; Apolipoproteins B; Betaine; Betaine-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Fatty Liver; Gene Transfer Techniques; Hepatocytes; Homocysteine; Humans; Lipid Metabolism; Liver Neoplasms; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Sterol Regulatory Element Binding Protein 1 | 2007 |
Influence of preconditioning-like hypoxia on the liver of developing methyl-deficient rats.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Proliferation; Choline Deficiency; Cystathionine beta-Synthase; Female; Folic Acid; Folic Acid Deficiency; Food, Formulated; Glutathione; Homocysteine; Hypoxia; Liver; Nitric Oxide Synthase Type II; Pregnancy; Rats; Rats, Wistar; Riboflavin; Riboflavin Deficiency; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Deficiency | 2007 |
gamma-Secretase is differentially modulated by alterations of homocysteine cycle in neuroblastoma and glioblastoma cells.
Topics: Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Antioxidants; Aspartic Acid Endopeptidases; Blotting, Western; Cell Line, Tumor; DNA Methylation; DNA Primers; Folic Acid; Glioblastoma; Homocysteine; Humans; Neuroblastoma; Oxidative Stress; Polymerase Chain Reaction; Presenilin-1; S-Adenosylmethionine; Up-Regulation; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2007 |
Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver.
Topics: Alanine Transaminase; Animals; ATPases Associated with Diverse Cellular Activities; Chromosome Mapping; Disease Models, Animal; Down-Regulation; Embryo, Mammalian; Female; Gene Expression; Gene Expression Profiling; Glycine N-Methyltransferase; Glycogen; Glycogen Storage Disease; Hepatitis, Chronic; Homocysteine; Liver; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Polymerase Chain Reaction; Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Homocysteine, S-adenosylmethionine and S-adenosylhomocysteine are associated with retinal microvascular abnormalities: the Hoorn Study.
Topics: Aged; Aged, 80 and over; Arterioles; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Folic Acid; Follow-Up Studies; Glucose Tolerance Test; Homocysteine; Humans; Male; Middle Aged; Retinal Diseases; Retinal Vessels; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
Ethanol-induced increased endogenous homocysteine levels and decreased ratios of SAM/SAH are only partially attenuated by exogenous glycine in developing chick brains.
Topics: Animals; Apoptosis; Brain; Caspase 3; Central Nervous System Depressants; Chick Embryo; Chickens; Down-Regulation; Embryonic Development; Enzyme Activation; Ethanol; Glycine; Homocysteine; S-Adenosylhomocysteine; S-Adenosylmethionine; Up-Regulation | 2008 |
[Efficacy and safety of heptral, vitamin B6 and folic acid during toxic hepatitis induced by CCL4].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Cytochromes b5; Disease Models, Animal; Drug Therapy, Combination; Female; Folic Acid; Follow-Up Studies; Hepatocytes; Homocysteine; Male; Rats; S-Adenosylmethionine; Treatment Outcome; Vitamin B 6; Vitamin B Complex | 2007 |
Homocysteine-mediated PPARalpha,gamma DNA methylation and its potential pathogenic mechanism in monocytes.
Topics: Base Sequence; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Activation; Foam Cells; Homocysteine; Humans; Lipoproteins, LDL; Macrophage Activation; Molecular Sequence Data; Monocytes; PPAR alpha; PPAR gamma; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetradecanoylphorbol Acetate | 2008 |
Evaluation of nutritional and genetic determinants of total homocysteine, methylmalonic acid and S-adenosylmethionine/S-adenosylhomocysteine values in Brazilian childbearing-age women.
Topics: Adult; Aging; Alleles; Anemia, Iron-Deficiency; Avitaminosis; Brazil; Female; Genotype; Homocysteine; Humans; Methylmalonic Acid; Nutritional Physiological Phenomena; Polymorphism, Genetic; Reproduction; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamins | 2008 |
Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.
Topics: Betaine; Betaine-Homocysteine S-Methyltransferase; Homocysteine; Homocysteine S-Methyltransferase; Humans; Metalloproteins; Methylation; Recombinant Proteins; S-Adenosylmethionine; Sarcosine; Substrate Specificity; Vitamin U; Zinc | 2008 |
Stability of plasma homocysteine, S-adenosylmethionine, and S-adenosylhomocysteine in EDTA, acidic citrate, and Primavette collection tubes.
Topics: Adult; Aged; Aged, 80 and over; Blood Specimen Collection; Citrates; Edetic Acid; Homocysteine; Humans; Hydrogen-Ion Concentration; Middle Aged; Plasma; S-Adenosylhomocysteine; S-Adenosylmethionine; Temperature | 2007 |
Folate deprivation increases tau phosphorylation by homocysteine-induced calcium influx and by inhibition of phosphatase activity: Alleviation by S-adenosyl methionine.
Topics: Calcium; Cell Line, Tumor; Drug Interactions; Enzyme Inhibitors; Folic Acid Deficiency; Homocysteine; Humans; N-Methylaspartate; Neuroblastoma; Okadaic Acid; Phosphoric Monoester Hydrolases; Phosphorylation; S-Adenosylmethionine; tau Proteins | 2008 |
Riboswitches that sense S-adenosylhomocysteine and activate genes involved in coenzyme recycling.
Topics: 5' Untranslated Regions; Base Sequence; Binding Sites; Coenzymes; Conserved Sequence; Gene Expression Regulation; Homocysteine; Kinetics; Methionine; Nucleic Acid Conformation; RNA; RNA, Bacterial; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
Hyperglycemia-induced membrane lipid peroxidation and elevated homocysteine levels are poorly attenuated by exogenous folate in embryonic chick brains.
Topics: Animals; Blood Glucose; Brain; Chick Embryo; Fatty Acids; Folic Acid; Glucose; Homocysteine; Lipid Peroxidation; Lipid Peroxides; Membrane Lipids; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
Interplay between cellular methyl metabolism and adaptive efflux during oncogenic transformation from chronic arsenic exposure in human cells.
Topics: Adenosylhomocysteinase; Arsenites; Cell Line; Cell Transformation, Neoplastic; Cystathionine beta-Synthase; DNA Methylation; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione; Homocysteine; Humans; Male; Methionine Adenosyltransferase; Multidrug Resistance-Associated Proteins; Prostate; S-Adenosylmethionine; Sodium Compounds | 2008 |
Elevated serum levels of S-adenosylhomocysteine, but not homocysteine, are associated with cardiovascular disease in stage 5 chronic kidney disease patients.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Chronic Disease; Female; Homocysteine; Humans; Kidney Diseases; Kidney Function Tests; Male; Middle Aged; Predictive Value of Tests; S-Adenosylhomocysteine; S-Adenosylmethionine; Sensitivity and Specificity; Severity of Illness Index | 2008 |
Epigenetic alterations in the brains of Fisher 344 rats induced by long-term administration of folate/methyl-deficient diet.
Topics: Animals; Brain; Diet, Reducing; DNA Modification Methylases; DNA-Binding Proteins; Epigenesis, Genetic; Folic Acid Deficiency; Homocysteine; Male; Methionine; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Regulatory Factor X Transcription Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Transcription Factors | 2008 |
Relationships between gene polymorphisms of folate-related proteins and vitamins and metabolites in pregnant women and neonates.
Topics: Adult; Brazil; DNA; Embryonic Development; Ethnicity; Female; Folic Acid; Glutamate Carboxypeptidase II; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Pregnancy; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylhomocysteine; S-Adenosylmethionine; Socioeconomic Factors; Vitamin B 12; Vitamin B Complex; Young Adult | 2008 |
Methionine metabolism in an animal model of sepsis.
Topics: Animals; Cysteine; Disease Models, Animal; Glutathione; Homocysteine; Lipopolysaccharides; Male; Methionine; Oxidation-Reduction; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Sepsis | 2008 |
Lack of effect of diet-induced hypomethylation on endothelium-dependent relaxation in rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atherosclerosis; Endothelium, Vascular; Folic Acid Deficiency; Homocysteine; In Vitro Techniques; Liver; Male; Methylation; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; S-Adenosylmethionine; Vasodilation; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Active cystathionine beta-synthase can be expressed in heme-free systems in the presence of metal-substituted porphyrins or a chemical chaperone.
Topics: Allosteric Site; Cobalt; Cystathionine beta-Synthase; Escherichia coli; Heme; Homocysteine; Humans; Manganese; Metals; Methylamines; Porphyrins; Protein Denaturation; Protein Folding; Recombinant Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae | 2008 |
Experimental folate and vitamin B12 deficiency does not alter bone quality in rats.
Topics: Animals; Biomarkers; Biomechanical Phenomena; Body Weight; Bone and Bones; Bone Remodeling; Disease Models, Animal; Female; Folic Acid Deficiency; Homocysteine; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2009 |
Hyperhomocysteinemia induces a tissue specific accumulation of homocysteine in bone by collagen binding and adversely affects bone.
Topics: Aged; Animals; Bone and Bones; Collagen; Female; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Methionine; Myocardium; Osteoporosis; Porosity; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Stress, Mechanical | 2009 |
Effects of insulin and glucose on cellular metabolic fluxes in homocysteine transsulfuration, remethylation, S-adenosylmethionine synthesis, and global deoxyribonucleic acid methylation.
Topics: Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Folic Acid; Glucose; Homocysteine; Humans; Insulin; Methionine; Methylation; S-Adenosylmethionine; Sulfur | 2009 |
Human polycomb 2 protein is a SUMO E3 ligase and alleviates substrate-induced inhibition of cystathionine beta-synthase sumoylation.
Topics: Cystathionine beta-Synthase; Cysteine; Enzyme Activation; Homocysteine; Humans; Ligases; Models, Molecular; Polycomb-Group Proteins; Protein Processing, Post-Translational; Repressor Proteins; S-Adenosylmethionine; Serine; SUMO-1 Protein; Ubiquitin-Protein Ligases | 2008 |
Hepatic cystathionine beta-synthase activity does not increase in response to methionine supplementation in rats fed a low casein diet: association with plasma homocysteine concentrations.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Caseins; Cystathionine beta-Synthase; Cysteine; Dietary Proteins; Dietary Supplements; Dose-Response Relationship, Drug; Energy Intake; Glycine; Homocysteine; Liver; Male; Methionine; Organ Size; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Weight Gain | 2009 |
Boron deprivation decreases liver S-adenosylmethionine and spermidine and increases plasma homocysteine and cysteine in rats.
Topics: Animals; Boron; Cysteine; Dinoprost; Female; Fish Oils; Homocysteine; Liver; Male; Oxidative Stress; Rats; S-Adenosylmethionine; Spermidine | 2009 |
Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Biomarkers; Case-Control Studies; Female; Genotype; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Neuropsychological Tests; Peptide Fragments; S-Adenosylmethionine; tau Proteins; Tetrahydrofolates; Young Adult | 2009 |
Methylation status and neurodegenerative markers in Parkinson disease.
Topics: Aged; alpha-Synuclein; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Biomarkers; Blood Platelets; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Nerve Degeneration; Parkinson Disease; Peptide Fragments; S-Adenosylhomocysteine; S-Adenosylmethionine; Substantia Nigra; Ultrasonography; Vitamin B 6 | 2009 |
Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis.
Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cells, Cultured; Choline Deficiency; Dietary Supplements; Disease Models, Animal; Fatty Liver; Female; Homocysteine; Liver; Liver Neoplasms; Methionine; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Unfolded Protein Response | 2009 |
Body mass index is an important determinant of methylation biomarkers in women of reproductive ages.
Topics: Adult; Biomarkers; Body Mass Index; Female; Fertility; Folic Acid; Homocysteine; Humans; Life Style; Methylation; Middle Aged; Multivariate Analysis; Netherlands; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2009 |
Impaired transmethylation potential in Parkinson's disease patients treated with L-Dopa.
Topics: Aged; Antiparkinson Agents; Cross-Sectional Studies; Erythrocytes; Female; Genotype; Homocysteine; Humans; Levodopa; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Enhanced one-carbon flux towards DNA methylation: Effect of dietary methyl supplements against gamma-radiation-induced epigenetic modifications.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carbon; Choline; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gamma Rays; Homocysteine; Male; Mice; S-Adenosylmethionine; Time Factors | 2010 |
Regulation of homocysteine metabolism and methylation in human and mouse tissues.
Topics: Animals; Computational Biology; Enzymes; Gene Expression Profiling; Gene Expression Regulation; Homocysteine; Humans; Infant, Newborn; Metabolic Networks and Pathways; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
S-adenosylmethionine prevents oxidative stress and modulates glutathione metabolism in TgCRND8 mice fed a B-vitamin deficient diet.
Topics: Animals; Diet; Dietary Supplements; Erythrocytes; Glutathione; Glutathione Transferase; Homocysteine; Lipid Peroxidation; Methylation; Mice; Oxidative Stress; S-Adenosylmethionine; Superoxide Dismutase; Vitamin B Deficiency | 2010 |
S-adenosylmethionine is decreased in the cerebrospinal fluid of patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Apolipoprotein E4; Chi-Square Distribution; Cross-Sectional Studies; Fasting; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Mental Status Schedule; Middle Aged; S-Adenosylmethionine; White People | 2010 |
Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.
Topics: Amino Acids; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine beta-Synthase; Diet; Enzyme Inhibitors; Glycine N-Methyltransferase; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Pharmacological activation and genetic manipulation of cystathionine beta-synthase alter circulating levels of homocysteine and hydrogen sulfide in mice.
Topics: Adenoviridae; Animals; Cystathionine beta-Synthase; Enzyme Activation; Genetic Engineering; Homocysteine; Humans; Hydrogen Sulfide; Male; Mice; Mice, Inbred C57BL; Mutation; Recombinant Proteins; S-Adenosylmethionine | 2011 |
Some more comments on 'folate deficiency in chronic pancreatitis'.
Topics: Folic Acid Deficiency; Glycine N-Methyltransferase; Homocysteine; Humans; Metabolic Networks and Pathways; Methionine; Pancreatitis, Chronic; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.
Topics: Carcinoma, Hepatocellular; Cysteine; Cytidine; DNA Methylation; DNA Modification Methylases; Gene Expression; Glycine N-Methyltransferase; Hep G2 Cells; Hepatocytes; Homeostasis; Homocysteine; Humans; Kinetics; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Osmolar Concentration; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
High bone concentrations of homocysteine are associated with altered bone morphology in humans.
Topics: Adult; Aged; Aged, 80 and over; Bone and Bones; Collagen; Extracellular Matrix; Female; Femur; Hip; Homocysteine; Humans; Male; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
A maternal dietary pattern characterised by fish and seafood in association with the risk of congenital heart defects in the offspring.
Topics: Adult; Biomarkers; Case-Control Studies; Feeding Behavior; Female; Fish Products; Heart Defects, Congenital; Homocysteine; Humans; Methylation; Netherlands; Odds Ratio; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Seafood; Surveys and Questionnaires; Vitamin B Complex | 2011 |
Homocysteine-induced cardiomyocyte apoptosis and plasma membrane flip-flop are independent of S-adenosylhomocysteine: a crucial role for nuclear p47(phox).
Topics: Adenosine; Adenosine Triphosphate; Animals; Apoptosis; Caspase 3; Cell Membrane; Cell Nucleus; Cell Survival; Extracellular Space; Homocysteine; Intracellular Space; Membrane Glycoproteins; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Phospholipid Transfer Proteins; Rats; Reactive Oxygen Species; S-Adenosylhomocysteine; S-Adenosylmethionine; Tyrosine | 2011 |
Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Cysteine; Diet; Enzyme Inhibitors; Fatty Liver; Glutathione; Homeostasis; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 2011 |
Adenosine kinase deficiency disrupts the methionine cycle and causes hypermethioninemia, encephalopathy, and abnormal liver function.
Topics: Adenosine Kinase; Adult; Amino Acid Metabolism, Inborn Errors; Brain Diseases; Child; Developmental Disabilities; Family Health; Female; Fibroblasts; Homocysteine; Humans; Liver Diseases; Male; Methionine; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
Plasma homocysteine level and hepatic sulfur amino acid metabolism in mice fed a high-fat diet.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Amino Acids, Sulfur; Animals; Cardiovascular Diseases; Cystathionine beta-Synthase; Cysteine Dioxygenase; Diet, High-Fat; Dipeptides; Down-Regulation; Homocysteine; Lipid Peroxidation; Liver; Male; Methionine Adenosyltransferase; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides; Up-Regulation | 2013 |
The association between plasma homocysteine levels, methylation capacity and incident osteoporotic fractures.
Topics: Aged; Bone Density; Female; Homocysteine; Humans; Incidence; Linear Models; Methylation; Middle Aged; Netherlands; Osteoporotic Fractures; Proportional Hazards Models; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine | 2012 |
Relationships among biomarkers of one-carbon metabolism.
Topics: Adult; Aging; Biomarkers; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; One-Carbon Group Transferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Characteristics; Vitamin B 12; Young Adult | 2012 |
Dimethylarginines, homocysteine metabolism, and cerebrospinal fluid markers for Alzheimer's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Biomarkers; Female; Homocysteine; Humans; Male; Middle Aged; S-Adenosylmethionine; Young Adult | 2012 |
Biomarkers of the one-carbon pathway in association with congenital diaphragmatic hernia.
Topics: Adult; Biomarkers; Birth Weight; Female; Fetal Blood; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Homocysteine; Humans; Infant, Newborn; Male; Regression Analysis; S-Adenosylhomocysteine; S-Adenosylmethionine | 2012 |
Determinants of the essential one-carbon metabolism metabolites, homocysteine, S-adenosylmethionine, S-adenosylhomocysteine and folate, in cerebrospinal fluid.
Topics: Adult; Aged; Aging; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Immunoassay; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry; Vitamin B 12 | 2012 |
The comprehensive effects of hyperlipidemia and hyperhomocysteinemia on pathogenesis of atherosclerosis and DNA hypomethylation in ApoE-/- mice.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cholesterol; Cholesterol, Dietary; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Gene Expression; Homocysteine; Hyperhomocysteinemia; Hyperlipidemias; Lipids; Male; Methionine; Mice; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2012 |
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 2013 |
Lowering homocysteine levels may prevent cardiovascular impairments? Possible therapeutic behaviors.
Topics: Acetylcysteine; Aspirin; Blood Vessels; Cardiovascular Diseases; Clopidogrel; Diuretics; Fatty Acids, Omega-3; Folic Acid; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Platelet Aggregation Inhibitors; S-Adenosylmethionine; Ticlopidine; Vitamin B 12; Vitamin B 6 | 2012 |
The relationship between intracellular and plasma levels of folate and metabolites in the methionine cycle: a model.
Topics: Cystathionine beta-Synthase; Down Syndrome; Folic Acid; Folic Acid Deficiency; Half-Life; Homocysteine; Humans; Methionine; Methylation; Models, Theoretical; Nutrition Surveys; Nutritional Status; Oxidative Stress; S-Adenosylmethionine; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamins | 2013 |
Downregulation of Cdc6 and pre-replication complexes in response to methionine stress in breast cancer cells.
Topics: Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Chromatin; Cyclin-Dependent Kinase 2; Down-Regulation; Female; G1 Phase Cell Cycle Checkpoints; Homocysteine; Humans; MCF-7 Cells; Mechanistic Target of Rapamycin Complex 1; Methionine; Multiprotein Complexes; Nuclear Proteins; Phosphorylation; Proteins; Proto-Oncogene Proteins c-akt; S-Adenosylmethionine; TOR Serine-Threonine Kinases | 2012 |
Hepatic metabolism of sulfur amino acids in db/db mice.
Topics: Amino Acids, Sulfur; Animals; Betaine-Homocysteine S-Methyltransferase; Cysteine; Cysteine Dioxygenase; Diabetes Mellitus, Experimental; Dipeptides; Glutathione; Homocysteine; Ligases; Lipid Peroxidation; Liver; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred C57BL; Putrescine; Receptors, Leptin; S-Adenosylmethionine; Spermidine; Taurine; Triglycerides; Up-Regulation | 2013 |
Tissue-specific relationship of S-adenosylhomocysteine with allele-specific H19/Igf2 methylation and imprinting in mice with hyperhomocysteinemia.
Topics: Alleles; Animals; Base Sequence; Body Weight; Brain; Crosses, Genetic; Diet; DNA Methylation; Female; Genetic Loci; Genomic Imprinting; Homocysteine; Hyperhomocysteinemia; Insulin-Like Growth Factor II; Liver; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Organ Specificity; RNA, Long Noncoding; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity | 2013 |
LC-MS/MS identification of the one-carbon cycle metabolites in human plasma.
Topics: Adult; Chromatography, Liquid; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Multiple Sclerosis; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry | 2013 |
Methylation metabolism in sepsis and systemic inflammatory response syndrome.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; DNA Methylation; Female; Homocysteine; Humans; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sepsis; Systemic Inflammatory Response Syndrome; Young Adult | 2013 |
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult | 2013 |
Effects of hyperhomocysteinemia and betaine-homocysteine S-methyltransferase inhibition on hepatocyte metabolites and the proteome.
Topics: Apolipoprotein A-I; Apoptosis; Betaine-Homocysteine S-Methyltransferase; Blotting, Western; Cell Proliferation; Cells, Cultured; Colorectal Neoplasms; Electrophoresis, Gel, Two-Dimensional; Fibrinogen; Hepatocytes; Homocysteine; Humans; Hyperhomocysteinemia; Liver Neoplasms; Male; Metabolomics; Middle Aged; Protein Multimerization; Proteome; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
A novel role of the tumor suppressor GNMT in cellular defense against DNA damage.
Topics: Adenosine; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleus; Cells, Cultured; Chromatography, High Pressure Liquid; Dietary Supplements; DNA Damage; DNA Methylation; Female; Fluorescent Antibody Technique, Indirect; Folic Acid; Glycine N-Methyltransferase; Hepatocytes; Homocysteine; Humans; Liver; Liver Neoplasms; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Knockout; Minor Histocompatibility Antigens; Protein Transport; Purines; Pyrimidines; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Uracil | 2014 |
Levels of key enzymes of methionine-homocysteine metabolism in preeclampsia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Female; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Plasma sulfur amino acids and stearoyl-CoA desaturase activity in two Caucasian populations.
Topics: Adipose Tissue; Aged; Aged, 80 and over; Amino Acids, Sulfur; Cohort Studies; Cross-Sectional Studies; Cystathionine; Cysteine; Diet; Dipeptides; Exercise; Fatty Acids; Female; Glutathione; Homocysteine; Humans; Male; Methionine; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Stearoyl-CoA Desaturase; Surveys and Questionnaires; White People | 2013 |
Maternal methyl donors supplementation during lactation prevents the hyperhomocysteinemia induced by a high-fat-sucrose intake by dams.
Topics: Animals; Body Weight; Diet, High-Fat; Dietary Sucrose; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Female; Homocysteine; Hyperhomocysteinemia; Lactation; Male; Maternal Nutritional Physiological Phenomena; Obesity; Pregnancy; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylmethionine | 2013 |
Genetic variants of homocysteine metabolism and multiple sclerosis: a case-control study.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Case-Control Studies; Cystathionine beta-Synthase; Female; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multiple Sclerosis; Polymorphism, Genetic; S-Adenosylmethionine | 2014 |
S-adenosylhomocysteine is associated with subclinical atherosclerosis and renal function in a cardiovascular low-risk population.
Topics: Asymptomatic Diseases; Atherosclerosis; Cardiovascular Diseases; Female; Glomerular Filtration Rate; Homocysteine; Humans; Male; Middle Aged; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine | 2014 |
Folate and cobalamin modify associations between S-adenosylmethionine and methylated arsenic metabolites in arsenic-exposed Bangladeshi adults.
Topics: Adult; Aged; Arsenic; Arsenic Poisoning; Arsenicals; Bangladesh; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2014 |
Effect of vitamin B deprivation during pregnancy and lactation on homocysteine metabolism and related metabolites in brain and plasma of mice offspring.
Topics: Animals; Brain; Female; Folic Acid; Homocysteine; Lactation; Male; Mice; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamin B Deficiency | 2014 |
Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression.
Topics: Cell Adhesion; Endothelial Cells; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Leukocytes; Methylation; Methyltransferases; Oxidative Stress; RNA, Transfer, Amino Acyl; RNA, Transfer, Ser; S-Adenosylhomocysteine; S-Adenosylmethionine; Selenium; Selenoproteins | 2014 |
Aberrant DNA methylation of the PDGF gene in homocysteine‑mediated VSMC proliferation and its underlying mechanism.
Topics: Cell Proliferation; Cells, Cultured; DNA Methylation; Folic Acid; G1 Phase Cell Cycle Checkpoints; Homocysteine; Humans; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Promoter Regions, Genetic; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Umbilical Cord | 2014 |
Increased methylation demand exacerbates ethanol-induced liver injury.
Topics: Alcohol Drinking; Amidinotransferases; Animals; Chemical and Drug Induced Liver Injury; Diet; Ethanol; Fatty Liver, Alcoholic; Glycine; Guanidinoacetate N-Methyltransferase; Homocysteine; Liver; Male; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2014 |
Quantification of folate metabolites in serum using ultraperformance liquid chromatography tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Leucovorin; Limit of Detection; Neural Tube Defects; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry; Tetrahydrofolates | 2014 |
Sinefungin, a natural nucleoside analogue of S-adenosylmethionine, inhibits Streptococcus pneumoniae biofilm growth.
Topics: Adenosine; Animals; Biofilms; Colony Count, Microbial; Gene Expression Regulation, Bacterial; Homocysteine; Otitis Media; Plankton; Rats, Sprague-Dawley; S-Adenosylmethionine; Streptococcus pneumoniae | 2014 |
Homocysteine accelerates senescence of endothelial cells via DNA hypomethylation of human telomerase reverse transcriptase.
Topics: Angiotensin II; Animals; Binding Sites; CCCTC-Binding Factor; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; DNA Methylation; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Male; Mice, Inbred C57BL; Promoter Regions, Genetic; Repressor Proteins; RNA Interference; S-Adenosylmethionine; Sp1 Transcription Factor; Telomerase; Telomere; Telomere Shortening; Time Factors; Transfection; Tumor Suppressor Protein p53 | 2015 |
Whey protein supplementation increases methionine intake but not homocysteine plasma concentration in rats.
Topics: Advanced Oxidation Protein Products; Animals; Biomarkers; Caseins; Dietary Supplements; Glutathione; Homocysteine; Hyperhomocysteinemia; Lipid Peroxidation; Liver; Male; Methionine; Muscle, Skeletal; Oxidation-Reduction; Oxidative Stress; Random Allocation; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Whey Proteins | 2015 |
Plasma homocysteine and liver tissue S-adenosylmethionine, S-adenosylhomocysteine status in vitamin B6-deficient rats.
Topics: Animals; Glutathione Peroxidase; Glutathione Transferase; Homocysteine; Liver; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 6 Deficiency | 2015 |
L-serine supplementation attenuates alcoholic fatty liver by enhancing homocysteine metabolism in mice and rats.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Dietary Supplements; Energy Intake; Ethanol; Fatty Liver, Alcoholic; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Rats; Rats, Wistar; S-Adenosylmethionine; Serine; Triglycerides | 2015 |
Plasma thiols levels in Alzheimer's disease mice under diet-induced hyperhomocysteinemia: effect of S-adenosylmethionine and superoxide-dismutase supplementation.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Chromatography; Chromatography, High Pressure Liquid; Disease Models, Animal; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; S-Adenosylmethionine; Sulfhydryl Compounds; Superoxide Dismutase | 2015 |
Reversed phase and cation exchange liquid chromatography with spectrophotometric and elemental/molecular mass spectrometric detection for S-adenosyl methionine/S-adenosyl homocysteine ratios as methylation index in cell cultures of ovarian cancer.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Reverse-Phase; Cisplatin; DNA Methylation; Drug Resistance, Neoplasm; Female; Homocysteine; Humans; Methylation; Molecular Weight; Ovarian Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2015 |
S-Inosyl-L-Homocysteine Hydrolase, a Novel Enzyme Involved in S-Adenosyl-L-Methionine Recycling.
Topics: Amino Acid Sequence; Bacterial Proteins; Cloning, Molecular; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Homocysteine; Hydrolases; Inosine; Kinetics; Methanocaldococcus; Molecular Sequence Data; Molecular Structure; S-Adenosylmethionine; Substrate Specificity | 2015 |
Sulfur amino acid metabolism in Zucker diabetic fatty rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Animals; Area Under Curve; Betaine; Betaine-Homocysteine S-Methyltransferase; Cysteine; Dipeptides; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Homocysteine; Liver; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Rats; Rats, Zucker; S-Adenosylhomocysteine; S-Adenosylmethionine; Spermidine; Spermine; Taurine | 2015 |
LINE-1 hypomethylation induced by reactive oxygen species is mediated via depletion of S-adenosylmethionine.
Topics: Antioxidants; Cell Line; DNA Methylation; Glutathione; Homocysteine; Humans; Hydrogen Peroxide; Kidney; Long Interspersed Nucleotide Elements; Oxidants; Oxidative Stress; Reactive Oxygen Species; S-Adenosylmethionine; Urothelium | 2015 |
Prospective study of telomere length and LINE-1 methylation in peripheral blood cells: the role of B vitamins supplementation.
Topics: Aged; Blood Cells; Calcium; Cross-Sectional Studies; Dietary Supplements; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Long Interspersed Nucleotide Elements; Male; Middle Aged; Prospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Telomere; Tetrahydrofolates; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin D | 2016 |
NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Betaine; Blotting, Western; Cells, Cultured; Cysteine; Female; Glutathione; Hep G2 Cells; Homocysteine; Humans; Immunoenzyme Techniques; Liver; Liver Diseases; Methionine; Mice; Mice, Knockout; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; S-Adenosylmethionine | 2015 |
Regulation of Folate-Mediated One-Carbon Metabolism by Glycine N-Methyltransferase (GNMT) and Methylenetetrahydrofolate Reductase (MTHFR).
Topics: Animals; Carbon; DNA Damage; DNA Methylation; Folic Acid; Genotype; Glycine N-Methyltransferase; Hep G2 Cells; Homocysteine; Humans; Liver; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Neoplasms; Nucleotides; Nutritional Status; Purines; S-Adenosylmethionine; Uracil | 2015 |
An enzyme captured in two conformational states: crystal structure of S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii.
Topics: Adenosine; Adenosylhomocysteinase; Bacterial Proteins; Binding Sites; Biocatalysis; Bradyrhizobium; Crystallography, X-Ray; Escherichia coli; Gene Expression; Homocysteine; Models, Molecular; NAD; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
CO and CN- syntheses by [FeFe]-hydrogenase maturase HydG are catalytically differentiated events.
Topics: Carbon Monoxide; Catalysis; Catalytic Domain; Cyanides; Cysteine; Desulfovibrio desulfuricans; Homocysteine; Hydrogenase; Iron-Sulfur Proteins; Ligands; Protein Structure, Secondary; S-Adenosylmethionine; Tyrosine | 2016 |
Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Cell Line, Tumor; Colorectal Neoplasms; DNA Methylation; Homocysteine; Humans; Methionine; Neoplasms; RNA; S-Adenosylmethionine; Serine; Stress, Physiological | 2016 |
Ratio of S-adenosylmethionine to S-adenosylhomocysteine as a sensitive indicator of atherosclerosis.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Biomarkers; Chemokine CCL2; Disease Models, Animal; DNA Methylation; Fatty Acid-Binding Proteins; Homocysteine; Interspersed Repetitive Sequences; Male; Mice; Mice, Knockout; Plaque, Atherosclerotic; S-Adenosylhomocysteine; S-Adenosylmethionine; Superoxide Dismutase | 2016 |
Lack of global epigenetic methylation defects in CBS deficient mice.
Topics: Animals; Cystathionine beta-Synthase; Disease Models, Animal; DNA; DNA Methylation; Epigenesis, Genetic; Epigenomics; Homocysteine; Homocystinuria; Kidney; Liver; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine | 2017 |
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium | 2016 |
The effect of increasing concentrations of dl-methionine and 2-hydroxy-4-(methylthio) butanoic acid on hepatic genes controlling methionine regeneration and gluconeogenesis.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Animals; Animals, Newborn; Betaine; Betaine-Homocysteine S-Methyltransferase; Carnitine O-Palmitoyltransferase; Cattle; Down-Regulation; Gluconeogenesis; Glucose-6-Phosphatase; Hepatocytes; Homocysteine; Liver; Methionine; Methionine Adenosyltransferase; Methylenetetrahydrofolate Reductase (NADPH2); Phosphoenolpyruvate Carboxykinase (GTP); S-Adenosylmethionine; Up-Regulation | 2016 |
Homocysteine metabolism is associated with cerebrospinal fluid levels of soluble amyloid precursor protein and amyloid beta.
Topics: Adult; Albumins; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Apolipoprotein E4; Female; Folic Acid; Healthy Volunteers; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Peptide Fragments; Reference Values; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 2016 |
Methionine Metabolites in Patients With Sepsis.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Catheter-Related Infections; Cohort Studies; Female; Homocysteine; Hospital Mortality; Humans; Intraabdominal Infections; Logistic Models; Male; Methionine; Middle Aged; Prognosis; Prospective Studies; Respiratory Tract Infections; S-Adenosylhomocysteine; S-Adenosylmethionine; Sepsis; Skin Diseases, Infectious; Urinary Tract Infections | 2018 |
Prolonged feeding with guanidinoacetate, a methyl group consumer, exacerbates ethanol-induced liver injury.
Topics: Alanine Transaminase; Amidinotransferases; Animals; Aspartate Aminotransferases; Body Weight; Calcium-Binding Proteins; Cholesterol; Dietary Supplements; DNA-Binding Proteins; Ethanol; Fatty Acids; Fatty Liver; Glycine; Guanidinoacetate N-Methyltransferase; Homocysteine; Inflammation; Insulin; Liver; Liver Diseases; Male; Nerve Tissue Proteins; Nucleobindins; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2016 |
Aberrant promoter methylation of multiple genes in VSMC proliferation induced by Hcy.
Topics: Alu Elements; Atherosclerosis; Cell Proliferation; CpG Islands; DNA Methylation; Epigenesis, Genetic; Female; GTP Phosphohydrolases; Homocysteine; Humans; Long Interspersed Nucleotide Elements; Mitochondrial Proteins; Models, Biological; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Primary Cell Culture; Promoter Regions, Genetic; PTEN Phosphohydrolase; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Suppressor Protein p53; Umbilical Veins | 2017 |
Crystal structure of cystathionine β-synthase from honeybee Apis mellifera.
Topics: Amino Acid Sequence; Animals; Bees; Crystallography, X-Ray; Cystathionine beta-Synthase; Cysteine; Homocysteine; Humans; Insect Proteins; Models, Molecular; Protein Conformation; Protein Multimerization; S-Adenosylmethionine; Sequence Homology, Amino Acid; Substrate Specificity | 2018 |
Acute exercise alters homocysteine plasma concentration in an intensity-dependent manner due increased methyl flux in liver of rats.
Topics: Animals; Body Weight; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine Adenosyltransferase; Methylation; Physical Conditioning, Animal; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Swimming | 2018 |
Probiotics Affect One-Carbon Metabolites and Catecholamines in a Genetic Rat Model of Depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium longum; Biomarkers; Depression; Dopamine; Dopamine Antagonists; Freeze Drying; Hippocampus; Homocysteine; Lactobacillus helveticus; Liver; Male; Methylation; Neurons; Norepinephrine; Prefrontal Cortex; Probiotics; Random Allocation; Rats, Mutant Strains; S-Adenosylmethionine | 2018 |
Topics: Atherosclerosis; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Melatonin; Mitochondria; Oxidative Phosphorylation; Oxidative Stress; S-Adenosylmethionine; Vitamin B 12 | 2018 |
Caloric restriction can affect one-carbon metabolism during pregnancy in the rat: A transgenerational model.
Topics: Animals; Betaine; Caloric Restriction; Carbon; Choline; DNA Methylation; Female; Gene Expression; Homocysteine; Hydrolases; Liver; Male; Methylamines; Models, Biological; Pregnancy; Pregnancy, Animal; Rats, Wistar; S-Adenosylmethionine | 2018 |
The high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) may explain naked mole-rat's distinct methionine metabolite profile compared to mouse.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Enzyme Activation; Homocysteine; Homocystinuria; Methionine; Mice; Mole Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 2018 |
Evaluating the therapeutic potential of one-carbon donors in nonalcoholic fatty liver disease.
Topics: Animals; Betaine; Carbon; Choline; Diet, High-Fat; Dietary Supplements; DNA Methylation; Folic Acid; Glutathione; Homocysteine; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; S-Adenosylmethionine | 2019 |
Altered Methionine Metabolism in Cancer Cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Homocysteine; Humans; Methionine; Methylation; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine | 2019 |
Interaction of nutrition and genetics via DNMT3L-mediated DNA methylation determines cognitive decline.
Topics: Aged; Aged, 80 and over; Atrophy; Brain; Cognition; Cognitive Dysfunction; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Homocysteine; Humans; Male; S-Adenosylmethionine; Spatial Memory; Vitamin B Complex | 2019 |
Hyperhomocysteinemia is key for increased susceptibility to PND in aged mice.
Topics: Animals; Cognition; Dietary Supplements; Folic Acid; Homocysteine; Hyperhomocysteinemia; Mice; Postoperative Cognitive Complications; Postoperative Period; Preoperative Period; Risk Factors; S-Adenosylmethionine; Vitamin B 12 | 2019 |
Blockade of the trans-sulfuration pathway in acute pancreatitis due to nitration of cystathionine β-synthase.
Topics: Animals; Ceruletide; Cystathionine; Cystathionine beta-Synthase; Cysteine; Disease Models, Animal; Glutathione; Homocysteine; Male; Mice; Nitric Oxide Synthase Type II; Pancreatitis; S-Adenosylmethionine; Up-Regulation | 2020 |
The impact of B vitamins on the functioning of methylation cycle in the liver and the kidneys of hyper- and hypothyroid rats.
Topics: Animals; Homocysteine; Humans; Hypothyroidism; Liver; Methylation; Rats; S-Adenosylmethionine; Vitamin B Complex | 2020 |
Transglutaminase-mediated assembly of multi-enzyme pathway onto TMV brush surfaces for synthesis of bacterial autoinducer-2.
Topics: Bacteria; Genetic Engineering; Gold; Homocysteine; Homoserine; Lactones; Metabolic Networks and Pathways; Microarray Analysis; S-Adenosylmethionine; Tobacco Mosaic Virus; Transglutaminases; Virion | 2020 |
Urine S-Adenosylmethionine are Related to Degree of Renal Insufficiency in Patients with Chronic Kidney Disease.
Topics: Adult; Aged; Aged, 80 and over; Female; Glomerular Filtration Rate; Homocysteine; Humans; Male; Middle Aged; Renal Insufficiency, Chronic; S-Adenosylhomocysteine; S-Adenosylmethionine | 2021 |
Intracellular homocysteine metabolites in SLE: plasma S-adenosylhomocysteine correlates with coronary plaque burden.
Topics: Adult; Aged; Female; Homocysteine; Humans; Leukocytes, Mononuclear; Lupus Erythematosus, Systemic; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine | 2021 |
Cross-sectional association between vitamin B12 status and probable postpartum depression in Indian women.
Topics: Adolescent; Adult; Cesarean Section; Cross-Sectional Studies; Depression, Postpartum; Diet; Female; Homocysteine; Humans; India; Methylmalonic Acid; Pregnancy; Pregnancy, Unplanned; Risk Factors; S-Adenosylmethionine; Serotonin; Social Class; Tetrahydrofolates; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2021 |
Duodenal-jejunal bypass maintains hepatic S-adenosylmethionine/S-homocysteine ratio in diet-induced obese rats.
Topics: Animals; Diet, High-Fat; Duodenum; Homocysteine; Jejunum; Liver; Mice; Obesity; Phosphatidylethanolamine N-Methyltransferase; Rats; S-Adenosylmethionine | 2021 |
Cholecalciferol and metformin protect against lipopolysaccharide-induced endothelial dysfunction and senescence by modulating sirtuin-1 and protein arginine methyltransferase-1.
Topics: Antioxidants; Arginine; Cell Cycle Checkpoints; Cell Line; Cellular Senescence; Cholecalciferol; Endothelium; Homocysteine; Humans; Lipopolysaccharides; Metformin; Methylation; NAD; Nitric Oxide; Protective Agents; Protein-Arginine N-Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Sirtuin 1; Telomerase; Vitamin D Response Element | 2021 |
One-carbon metabolism during the menstrual cycle and pregnancy.
Topics: Carbon; Estradiol; Female; Folic Acid; Homocysteine; Humans; Menstrual Cycle; Pregnancy; S-Adenosylmethionine; Vitamin B 12 | 2021 |
Improved methylation in E. coli via an efficient methyl supply system driven by betaine.
Topics: Adenosine Triphosphate; Betaine; Escherichia coli; Homocysteine; Methylation; Methyltransferases; S-Adenosylmethionine | 2022 |
Dithiothreitol causes toxicity in
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dithiothreitol; Endoplasmic Reticulum; Homocysteine; S-Adenosylmethionine | 2022 |
Dietary-derived vitamin B12 protects Caenorhabditis elegans from thiol-reducing agents.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Caenorhabditis elegans; Carbon; Dithiothreitol; Folic Acid; Homocysteine; Hydrogen Sulfide; Ligases; Lipids; Mercaptoethanol; Methionine; Methyltransferases; Nucleic Acids; Oxygen; Reducing Agents; S-Adenosylmethionine; Sulfhydryl Compounds; Vitamin B 12; Vitamins | 2022 |
Revisiting One-Carbon Metabolites in Human Breast Milk: Focus on S-Adenosylmethionine.
Topics: Adult; Carbon; Child; Chromatography, Liquid; Female; Homocysteine; Humans; Infant; Methionine; Milk, Human; Racemethionine; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry | 2023 |
Lack of Association of
Topics: Breast Neoplasms; Female; Homocysteine; Humans; Mali; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); S-Adenosylmethionine | 2023 |
Optimization of Hydrogenobyrinic Acid Synthesis in a Cell-Free Multienzyme Reaction by Novel
Topics: Cell-Free System; Homocysteine; Methionine; Methyltransferases; S-Adenosylmethionine | 2023 |
NAD+ enhances the activity and thermostability of S-adenosyl-L-homocysteine hydrolase from Pyrococcus horikoshii OT3.
Topics: Homocysteine; Hydrolases; NAD; Pyrococcus horikoshii; S-Adenosylhomocysteine; S-Adenosylmethionine | 2023 |
Enzymatic Synthesis of l-Methionine Analogues and Application in a Methyltransferase Catalysed Alkylation Cascade.
Topics: Alkylation; Catalysis; Homocysteine; Homoserine; Methionine; Methyltransferases; S-Adenosylmethionine | 2023 |
Serum 5-Methyltetrahydrofolate Status Is Associated with One-Carbon Metabolism-Related Metabolite Concentrations and Enzyme Activity Indicators in Young Women.
Topics: Adolescent; Adult; Betaine; Carbon; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Pregnancy; S-Adenosylmethionine; Young Adult | 2023 |
The importance of preconception Hcy testing: identification of a folate trap syndrome in a woman attending an assisted reproduction program.
Topics: Female; Folic Acid; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Reproduction; S-Adenosylmethionine | 2023 |