homocysteine has been researched along with s-adenosylhomocysteine in 405 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 201 (49.63) | 18.7374 |
| 1990's | 28 (6.91) | 18.2507 |
| 2000's | 105 (25.93) | 29.6817 |
| 2010's | 66 (16.30) | 24.3611 |
| 2020's | 5 (1.23) | 2.80 |
| Authors | Studies |
|---|---|
| Butt, VS; Poulton, JE | 1 |
| Bidard, JN; Cronenberger, L; Pacheco, H; Sokoloff, P | 1 |
| Deconinck, M; Gelbcke, M; Gillet, L; Léonis, J; Looze, Y | 1 |
| Deconinck, M; Gillet, L; Léonis, J; Looze, Y | 2 |
| Barailler, J; Cronenberger, L; Fonlupt, P; Pacheco, H; Roche, M | 1 |
| Kuchino, Y; Nishimura, S; Yasuda, T | 1 |
| Brock, ML; Lodish, HF; Rose, JK | 1 |
| Huppert, J; Jacquemont, B | 1 |
| Lawrence, F; Pierré, A; Richou, M; Robert-Géro, M; Vigier, P | 1 |
| Coward, J; Kaehler, M; Rottman, F | 1 |
| Bader, JP; Cantoni, GL; Chiang, PK; Montgomery, JA; Shannon, WM; Thomas, HJ | 1 |
| Berneman, A; Blanchard, P; Farrugia, G; Lawrence, F; Lederer, E; Robert-Géro, M; Vigier, P | 1 |
| Saebø, J; Ueland, PM | 1 |
| Duncan, GS; Wolberg, G; Zimmerman, TP | 1 |
| Hershfield, MS; Kredich, NM | 4 |
| Saebø, J; Ueland, M | 1 |
| Enouf, J; Lawrence, F; Lederer, E; Robert-Gero, M; Tempete, C | 1 |
| Borisov, BN; Borovkova, TV; Ermil'chenko, GV; Fedorov, NA; Vaniushin, BF | 1 |
| Furuichi, Y | 1 |
| Mertens, PP; Payne, CC | 2 |
| Chastain, B; Shugart, L | 1 |
| Cornatzer, WE; Duerre, JA; Hoffman, DR | 1 |
| Coward, JK; Crooks, PA; Dreyer, RN | 1 |
| Johnston, JM; Kredich, NM | 1 |
| Cronenberger, L; Fonlupt, P; Pacheco, H; Roche, M | 3 |
| Coward, JK; Lesko, N; Michelot, RJ; Stout, RW | 1 |
| Mitsuda, H; Nadamoto, T; Nakajima, K | 1 |
| Eloranta, TO | 1 |
| Kredich, NM; Martin, DV | 1 |
| Yu, PH | 1 |
| Hoffman, JL | 2 |
| Hibasami, H; Pegg, AE | 1 |
| Casellas, P; Jeanteur, P | 1 |
| Borchardt, RT; Glick, JM; Haney, S; Leboy, PS; Steiner, FG | 1 |
| Fuller, RW; Nagarajan, R | 1 |
| Borchardt, RT; Wu, BS; Wu, YS | 3 |
| Finkelstein, JD; Grossman, MR; Harris, BJ; Morris, HP | 1 |
| Farrugia, G; Lederer, E; Legreverend, M; Michelot, R | 1 |
| Cox, R; Irving, CC; Prescott, C | 1 |
| Schatz, RA; Sellinger, OZ; Vunnam, CR | 1 |
| Cantoni, GL; Chiang, PK; Richards, HH | 1 |
| Borchardt, RT; Pugh, CS; Stone, HO | 1 |
| Kerr, SJ; Trewyn, RW | 1 |
| Legraverend, M; Michelot, R | 1 |
| Borchardt, RT; Huber, JA; Wu, YS | 2 |
| Eloranta, TO; Kajander, EO; Raina, AM | 2 |
| Borchardt, RT | 1 |
| Hoffman, J | 1 |
| Chang, CD; Coward, JK | 2 |
| Glick, JM; Leboy, PS; Ross, S | 1 |
| Borchardt, RT; Wu, Y | 1 |
| Doherty, NS; Gieske, TH; Raddatz, R; Stephens, D | 1 |
| Balzarini, J; Cools, M; De Clercq, E | 1 |
| Borchardt, RT; Cools, M; De Clercq, E; Hasobe, M | 1 |
| Bottiglieri, T; Chanarin, I; Metz, J; Van der Westhuyzen, J; Vieira-Makings, E | 1 |
| Borchardt, RT; Kramer, DL; Porter, CW; Sufrin, JR | 1 |
| Borchardt, RT; Borcherding, DR; Hasobe, M; Keller, BT; Mckee, JG | 1 |
| Daino, L; Feo, F; Garcea, R; Pascale, R; Puddu, M; Ruggiu, ME; Satta, G; Seddaiu, MA; Sequenza, MJ; Simile, MM | 1 |
| Ellis, M; Frost, P; Judde, JG | 1 |
| Henning, SM; McKee, RW; Swendseid, ME | 1 |
| Gharib, A; Reynaud, D; Sarda, N | 1 |
| Borchardt, RT; Hasobe, M; McKee, JG | 1 |
| Deussen, A; Lloyd, HG; Schrader, J | 1 |
| Borchardt, RT; Cools, M; De Clercq, E; Hasobe, M; Ishii, H; McKee, JG | 1 |
| Hua, P; Nuske, JH | 1 |
| DeMeester, CA; Pike, MC | 1 |
| Borchardt, RT; De Gunzburg, J; Guitton, MC; Keller, BT; Part, D; Véron, M | 1 |
| Hunt, DM; Hutchinson, KL; Mehta, R | 1 |
| Djurhuus, R; Svardal, AM; Ueland, PM | 1 |
| Allen, PT; Hernandez, L; Lijinsky, W; Poirier, LA | 1 |
| Dyer, JR; Greenwood, CE | 1 |
| Newman, ME | 1 |
| Martínez del Pozo, A; Mato, JM; Mérida, I; Pajares, MA; Varela, I; Villalba, M | 1 |
| Fronko, GE; Henderson, EE; Lindemeyer, RG; Long, WK; Wu, B | 1 |
| Carreau, S; Drosdowsky, MA; Kamtchouing, P; Papadopoulos, V | 1 |
| Blanchflower, J; Keating, S; Kennedy, DG; Kennedy, S; McPartlin, J; Molloy, A; Rice, D; Scott, JM; Weir, DG | 1 |
| Shimizu, S; Yamada, H | 1 |
| Djurhuus, R; Lillehaug, JR; Male, R; Svardal, AM; Ueland, PM | 1 |
| Aarsaether, N; Aarsland, A; Berge, RK; Lønning, PE; Refsum, H; Svardal, AM; Ueland, PM | 1 |
| Borst, M; Deussen, A; Schrader, J | 1 |
| Borst, M; Deussen, A; Kroll, K; Schrader, J | 1 |
| Brothers, P; Speedie, MK; Zulty, JJ | 1 |
| Deussen, A; Lloyd, HG; Schrader, J; Wuppermann, H | 1 |
| Brasitus, TA; Dudeja, PK; Halline, AG | 1 |
| Lillehaug, JR; Male, R; Refsum, H; Ueland, PM | 1 |
| Chiang, PK; Gordon, RK; Miura, GA; Montgomery, JA | 1 |
| Helland, S; Ueland, PM | 4 |
| Stipanuk, MH | 1 |
| Ghag, S; Kiechle, FL; Sykes, E | 1 |
| Duerre, JA; Wallwork, JC | 1 |
| Svardal, AM; Ueland, PM | 1 |
| Carrera, CJ; Carson, DA; Kajander, EO; Kubota, M; Montgomery, JA | 1 |
| Crooks, PA; Godin, CS | 1 |
| Coindet, J; Gharib, A; Jouvet, M; Pacheco, H; Sarda, N | 1 |
| Djurhuus, R; Svardal, A; Ueland, PM | 1 |
| Djurhuus, R; Refsum, H; Svardal, AM; Ueland, PM | 1 |
| Hoffman, RM; Stern, PH | 2 |
| Serafinowski, P | 1 |
| Aiyar, VN; Hershfield, MS; Kurtzberg, J; Schiff, R; Suh, EJ | 1 |
| Archer, S; Chan, VL; Ho, JH; Juranka, PF | 1 |
| Carson, DA; Iizasa, T | 1 |
| Helland, S; Refsum, H; Ueland, PM | 1 |
| Loo, G; Smith, JT | 1 |
| Fonlupt, P; Gharib, A; Pacheco, H; Rey, C; Sarda, N | 1 |
| Salama, AI; Saller, CF | 1 |
| Chiang, PK; Miura, GA | 1 |
| Cantoni, GL | 1 |
| Gill, MW; Schatz, RA | 1 |
| Hill, MW; Mann, SP | 1 |
| Crooks, PA; Pinney, RJ; Tribé, MJ | 1 |
| Fuller, RW; Hemrick-Leucke, SK; Perry, KW | 1 |
| Glazer, RI; Hartman, KD | 1 |
| Morita, Y; Siraganian, RP | 1 |
| Ahl, R | 1 |
| Baglioni, C; de Ferra, F | 1 |
| Coindet, J; Gharib, A; Jouvet, M; Sarda, N | 1 |
| Dev, VG; Mixon, JC | 1 |
| Biot, N; Fonlupt, P; Macovschi, O; Pacheco, H; Pacheco, Y; Perrin-Fayolle, M | 1 |
| Albers, RJ; Camper, SA; Coward, JK; Rottman, FM | 1 |
| Hoffman, RM | 1 |
| Jouvet, M; Louis-Coindet, J; Pacheco, H; Sarda, N | 1 |
| Comte, N; Dubois, M; Fonlupt, P; Pacheco, H; Rey, C | 1 |
| Fonlupt, P; Pacheco, H; Rey, C | 4 |
| Robert-Gero, M; Tempete, C; Vedel, M | 1 |
| Cornatzer, WE; Haning, JA; Hoffman, DR | 2 |
| Robert-Géro, M; Vedel, M | 1 |
| Foster, NG; Goldblum, RM; Mills, GC | 1 |
| Christoffersen, T; Døskeland, SO; Ogreid, D; Refsnes, M; Sand, TE; Schanche, JS; Ueland, PM | 1 |
| Tisdale, MJ | 1 |
| Borchardt, RT; Pugh, CS | 1 |
| Dalgat, LD; Fedorov, NA; Kasavina, BS; Maĭchuk, IuF | 1 |
| Coalson, DW; Hoffman, RM; Mecham, JO; Stern, PH | 1 |
| Tudball, N | 1 |
| Holý, A; Schanche, JS; Schanche, T; Ueland, PM; Votruba, I | 1 |
| Porta, R; Schatz, RA; Sellinger, OZ; Wilens, TE | 1 |
| Rutledge, CO; Samet, MK | 1 |
| Barber, JR; Clarke, S | 1 |
| Carson, DA; Kamatani, N; Willis, EH | 1 |
| Falletta, JM; Hershfield, MS; Kinney, TR; Koller, CA; Kredich, NM; Kurtzberg, J; Mitchell, BS | 1 |
| Hilton, MA; Hoffman, JL; Sparks, MK | 1 |
| Chabannes, B; Fonlupt, P; Macovski, O; Pacheco, H | 1 |
| Ito, S | 1 |
| Jaiswal, RK; Landon, EJ; Sastry, BV | 1 |
| Aarbakke, J; Bessesen, A; Gadeholt, G; Schanche, JS; Schanche, T; Ueland, PM | 1 |
| Broch, OJ; Helland, S; Schanche, JS; Ueland, PM | 1 |
| Hoffman, RM; Stern, PH; Wallace, CD | 1 |
| Bobillier, P; Gharib, A; Pacheco, H; Sarda, N | 1 |
| Lukey, T; Snyder, FF | 1 |
| Chiang, PK | 1 |
| Kuwano, R; Takahashi, Y | 2 |
| Finkelstein, JD; Martin, JJ | 1 |
| Ueland, PM | 1 |
| Fox, IH; Herring, C; Palella, TD; Thompson, D | 1 |
| Porta, R; Schatz, RA; Sellinger, OZ; Tatter, SB | 1 |
| Chabannes, B; Gharib, A; Pachéco, H; Sarda, N | 1 |
| Pusch, R; Reddington, M | 1 |
| Poirier, LA; Shivapurkar, N | 1 |
| Kendall, HE; Kredich, NM; Spence, FJ | 1 |
| Jove, R; Manley, JL | 1 |
| Fox, IH; Palella, TD; Schatz, RA; Wilens, TE | 1 |
| Aksamit, RR; Cantoni, GL; Falk, W | 1 |
| Chabannes, B; Cronenberger, L; Gharib, A; Pacheco, H; Sarda, N | 1 |
| Finkelstein, JD; Harris, BJ; Kyle, WE; Martin, JJ | 1 |
| Dubois, M; Gharib, A; Jouvet, M; Sarda, N; Valatx, JL | 1 |
| Samejima, K; Yamanoha, B | 1 |
| Aarbakke, J; Bessesen, A; Ueland, PM | 1 |
| Borchardt, RT; Huber, JA; Kuonen, D; Moorman, A | 1 |
| Jakubowski, H | 1 |
| Schanche, JS; Schanche, T; Ueland, PM | 2 |
| Chabannes, B; Cronenberger, L; Gharib, A; Pachéco, H | 1 |
| Schatz, RA; Sellinger, OZ; Wilens, TE | 2 |
| Aarbakke, J; Ueland, PM | 1 |
| Gupta, KC; Roy, P | 1 |
| Bardenheuer, H; Schrader, J; Schütz, W | 1 |
| Chiang, PK; Montgomery, JA; Thomas, HJ; Thorpe, MC | 1 |
| Della Ragione, F; Galletti, P; Manna, C; Porcelli, M; Romeo, G | 1 |
| Arrang, JM; Bidart, JM; Bohuon, C; Christa, L | 1 |
| Satake, N | 1 |
| Andre, AC; Cronenberger, L; Fonlupt, P; Pacheco, H; Roche, M | 1 |
| Cornatzer, WE; Duerre, JA; Hoffman, DR; Marion, DW | 1 |
| Branno, M | 1 |
| Alonso-Aperte, E; Alvarez, L; Caballería, J; Deulofeu, R; Gassó, M; Mato, JM; Rodés, J; Rubio, M; Varela-Moreiras, G | 1 |
| Buc-Calderon, P; Tinton, S | 1 |
| Blom, HJ; Copius Peereboom-Stegeman, JH; Deabreu, RA; Eskes, TK; Noordhoek, J; Trijbels, FJ; Vanaerts, LA | 1 |
| De Santo, NG; Galletti, P; Ingrosso, D; Perna, AF; Zappia, V | 2 |
| Linder, M; Scholtissek, C; Woyciniuk, P | 1 |
| García-Cuevas, M; Pérez-Olleros, L; Ruiz-Roso, B; Varela-Moreiras, G | 1 |
| Bergmann, S; Lehmann, V; Ratter, F; Schiemann, S; Schulze-Osthoff, K; Shatrov, V | 1 |
| Kroll, K; Martin, GV | 1 |
| Fredholm, BB; Lindström, K; Lloyd, HG | 1 |
| Sciotti, VM; Van Wylen, DG | 1 |
| Allen, RH; Chandler, CJ; Halsted, CH; James, SJ; Muskhelishvili, L; Poirier, L; Stabler, SP; Villanueva, J | 1 |
| Blom, HJ; Bökkerink, JP; De Abreu, RA; Keuzenkamp-Jansen, CW; Trijbels, JM | 1 |
| Angst, CP; Browne, G; Fowler, B; Frick, G; Haefeli, WE; Loehrer, FM | 1 |
| Aarbakke, J; Endresen, PC; Kildalsen, H; Loennechen, T | 1 |
| Joseph, JA; Miller, JW; Nadeau, MR; Selhub, J; Shukitt-Hale, B; Villalobos-Molina, R | 1 |
| Deussen, A; Flesche, CW; Loncar, R | 1 |
| Angst, CP; Fowler, B; Haefeli, WE; Loehrer, FM; Schwab, R | 1 |
| Haber, E; Lai, K; Lee, ME; Perrella, MA; Tsai, JC; Wang, H; Yoshizumi, M | 1 |
| Brunone, M; De Santo, NG; Galletti, P; Ingrosso, D; Perna, AF; Zappia, V | 1 |
| Alfheim, I; Faaren, AL; Frantzen, F; Nordhei, AK | 1 |
| Angst, CP; Brunner, FP; Fowler, B; Haefeli, WE; Loehrer, FM | 1 |
| Cornelis, R; De Kimpe, J; Vanholder, R | 1 |
| James, SJ; Melnyk, S; Pogribna, M; Pogribny, IP; Yi, P | 1 |
| Donnelly, JG; Pronovost, C | 1 |
| Dudman, NP; Fu, W; Perry, MA; Wang, XL; Young, K | 1 |
| Hine, RJ; James, SJ; Melnyk, S; Pogribna, M; Pogribny, IP; Yi, P | 1 |
| Finkelstein, JD | 1 |
| Cerbone, AM; Coppola, A; Davi, G; De Stefano, V; Di Minno, G; Mancini, FP | 1 |
| Angst, CP; Fowler, B; Haefeli, WE; Jäger, K; Litynski, P; Loehrer, FM; Tschöpl, M | 1 |
| Deussen, A | 1 |
| Castaldo, P; Cimmino, A; De Santo, NG; di Carlo, E; Galletti, P; Ingrosso, D; Perna, AF; Zappia, V | 1 |
| Chango, A; James, SJ; Melnyk, S; Pogribna, M; Pogribny, I; Yi, P | 1 |
| Arning, E; Bottiglieri, T; Dayal, S; Faraci, FM; Heistad, DD; Lentz, SR; Maeda, N; Malinow, MR; Sigmund, CD | 1 |
| Delongchamp, RR; Poirier, LA; Sinha, R; Wise, CK | 1 |
| Ashihara, H; Crozier, A; Kato, A; Koshiishi, C; Yama, S | 1 |
| Brown, AT; Cruz, C; Drouilhet, J; Eidt, J; Moursi, MM; Mukunyadzi, P; Poirier, LA; Southern, F; Wang, YF; Williams, DK | 1 |
| Brown, AT; Delongchamp, RR; Fink, LM; Fonseca, VA; Poirier, LA; Randolph, CJ; Wise, CK | 1 |
| Caudill, MA; Cogger, EA; Collins, MD; James, SJ; Jernigan, S; Melnyk, S; Pogribny, IP; Santos-Guzman, J; Swendseid, ME; Wang, JC | 1 |
| Capdevila, A; Kerins, DM; Koury, MJ; Rana, S; Wagner, C | 1 |
| Delabar, U; Kloor, D; Luippold, G; Mühlbauer, B; Osswald, H | 1 |
| Desouza, C; Dicker-Brown, A; Fonseca, V; Keebler, M; McNamara, DB; Murthy, SN; Poirier, LA | 1 |
| Christopher, SA; James, SJ; Kruger, WD; Melnyk, S | 1 |
| Bagley, PJ; Choi, SW; Choumenkovitch, SF; Maeda, N; Nadeau, MR; Selhub, J; Smith, DE | 1 |
| Caudill, MA; James, SJ; Melnyk, S; Pogribna, M; Pogribny, IP | 1 |
| Alonso-Aperte, E; Ubeda, N; Varela-Moreiras, G | 1 |
| Zhu, BT | 1 |
| Junker, E; Lauterburg, BH; Russmann, S | 1 |
| Kim, YI; Mason, JB; Reid, S; Shirwadkar, S; Sohn, KJ; Stempak, JM | 1 |
| Mason, JB | 1 |
| Maruyama, Y; Miyazawa, T; Nakagawa, K | 1 |
| Blom, HJ; Camilo, ME; Castro, R; Jakobs, C; Jansen, EE; Ravasco, P; Rivera, I; Struys, EA; Tavares de Almeida, I | 1 |
| Blom, HJ; Boers, GH; Riksen, NP; Rongen, GA; Russel, FG; Smits, P | 1 |
| Davis, CD; Uthus, EO | 1 |
| CHUNG, AE; LAW, JH | 1 |
| Chen, A; Davidson, AG; Dyer, R; Innis, SM; James, SJ; Melnyk, S | 1 |
| Nijhout, HF; Reed, MC; Sparks, R; Ulrich, CM | 1 |
| Clarke, S; Vitali, R | 1 |
| Selley, ML | 1 |
| de Meer, K; Jakobs, C; Kulik, W; Smith, DE; Stam, F; Stehouwer, CD; ter Wee, PM; van Guldener, C | 1 |
| Han, Q; Hoffman, RM; Sun, X; Tan, Y; Tang, L; Xu, M; Zhang, N | 1 |
| Garrow, TA; Nieman, KM; Rowling, MJ; Schalinske, KL | 1 |
| Barve, S; Chen, T; Kang, YJ; McClain, CJ; Song, Z; Uriarte, S; Wang, L; Zhou, Z | 1 |
| Allen, RH; D'Almeida, V; Guerra-Shinohara, EM; Irazusta, SP; Morita, OE; Pagliusi, RA; Peres, S; Sampaio Neto, LF; Stabler, SP | 1 |
| Chen, CS; Chern, JW; Chien, TC; Yu, FH | 1 |
| Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA | 1 |
| Kocki, T; Lazarewicz, J; Luchowska, E; Luchowski, P; Paczek, R; Turski, WA; Urbanska, EM; Wielosz, M; Ziembowicz, A | 1 |
| Cleves, MA; Hobbs, CA; James, SJ; Melnyk, S; Zhao, W | 2 |
| Allen, R; Boger, R; Doshi, S; Goodfellow, J; Lewis, M; McDowell, I; Moat, S; Newcombe, R; Stabler, S | 1 |
| Chen, AH; Davidson, AG; Innis, SM; James, SJ | 1 |
| Amanlou, M; Dehghani, M; Dehpour, AR; Ebrahimkhani, MR; Farsam, H; Honar, H; Kiani, S; Mirazi, N; Pasalar, P; Payabvash, S; Riazi, K; Sadeghipour, H | 1 |
| Fowler, B; Herrmann, W; Kuhlmann, MK; Makowski, J; Obeid, R; Schorr, H | 1 |
| Luchowski, P; Stazka, J; Urbanska, EM | 1 |
| Afman, LA; Blom, HJ; Brouns, MR; Drittij, MJ; van Straaten, HW | 1 |
| Dupont, WD; Jabs, K; Koury, MJ; Wagner, C | 1 |
| Bermejo, E; Castro, M; Desviat, LR; Leal, F; Mansilla, E; Martínez-Fernández, ML; Martínez-Frías, ML; Pérez, B; Prieto, D; Rodríguez, L; Rodríguez-Pinilla, E; Ugarte, M | 1 |
| Davis, CD; Ross, SA; Uthus, EO | 1 |
| Fernstrom, JD; Mudd, SH | 1 |
| Kuhn, W; Müller, T | 1 |
| Blacquiere, KD; Coykendall, CE; Hay, CM; Honsey, LE; Miller, RR; Striegnitz, TR | 1 |
| Fukada, S; Kawagishi, H; Morita, T; Sekiya, A; Sugiyama, K | 1 |
| Antenucci, M; De Sole, P; Fasanella, S; Giardina, B; Minucci, A; Neri, P; Persichilli, S; Scribano, D; Zappacosta, B | 1 |
| Hu, ML; Yang, TH | 1 |
| Hermes, M; Kloor, D; Osswald, H | 1 |
| Hayakawa, T; Isa, Y; Tsuge, H | 1 |
| Allen, RH; Blaia-d'Avila, VL; Guerra-Shinohara, EM; Morita, OE; Pagliusi, RA; Stabler, SP | 1 |
| Baggott, JE; Tamura, T | 3 |
| Hu, ML; Lin, HG; Lin, PY; Yang, TH | 1 |
| Hayakawa, T; Isa, Y; Mishima, T; Tsuge, H | 1 |
| Colombatto, S; Grillo, MA | 1 |
| Blom, HJ; Boers, GH; Heil, SG; Riksen, NP; Smulders, Y | 1 |
| Bottiglieri, T; Cross, JC; Elmore, CL; Gravel, RA; Krupenko, NI; Krupenko, SA; Leclerc, D; Matthews, RG; Rozen, R; Watson, ED; Wu, X | 1 |
| Alonso-Aperte, E; González, MP; Póo-Prieto, R; Varela-Moreiras, G | 1 |
| Achón, M; Alonso-Aperte, E; Ubeda, N; Varela-Moreiras, G | 1 |
| Cillessen, SA; Giroth, CP; Jakobs, C; Krijnen, PA; Meischl, C; Muller, A; Musters, RJ; Niessen, HW; Rauwerda, JA; Roos, D; Sipkens, JA; Smith, DE; Smulders, YM; Spreeuwenberg, MD; Stehouwer, CD; van Hinsbergh, VW | 1 |
| Allen, RH; Barbosa, PR; Braga, RC; Guerra-Shinohara, EM; Hirata, MH; Hirata, RD; Machado, AL; Sampaio-Neto, LF; Stabler, SP | 1 |
| Almo, SC; Fedorov, AA; Fedorov, E; Hermann, JC; Marti-Arbona, R; Raushel, FM; Shoichet, BK | 1 |
| Jianzhong, Z; Jinge, Z; Juan, S; Shenglan, W; Shuren, W; Xiaoqun, H; Yideng, J; Ying, H | 1 |
| Chan, C; Ji, C; Kaplowitz, N; Kuhlenkamp, J; Shinohara, M | 1 |
| Alberto, JM; Audonnet-Blaise, S; Blaise, SA; Daval, JL; Guéant, JL | 1 |
| Chen, YJ; Chen, YM; Chiang, EP; Hsiao, M; Huang, SF; Hwang, SF; Lee, YH; Li, AF; Li, YS; Liu, SP; Tsai, TF | 1 |
| Bouter, LM; Dekker, JM; Heine, RJ; Jakobs, C; Nijpels, G; Polak, BC; Stehouwer, CD; Stolk, RP; Teerlink, T; Van Hecke, MV | 1 |
| Miller, RR; Walcher, BN | 1 |
| Guizhong, L; Jiantuan, X; Jun, C; Shuren, W; Yideng, J; Zhihong, L | 1 |
| Allen, RH; Barbosa, PR; Carvalho, FR; Guerra-Shinohara, EM; Hirata, MH; Hirata, RD; Luchessi, AD; Stabler, SP; Trentin, R | 1 |
| Koury, MJ; Wagner, C | 2 |
| Guo, H; Hou, M; Hu, Y; Ling, W; Liu, C; Ma, J; Tang, Z; Wang, Q; Xia, M; Yuan, Q; Zhu, H | 1 |
| Eckert, R; Geisel, J; Herrmann, W; Hübner, U; Schorr, H | 1 |
| Breaker, RR; Lee, ER; Lim, J; Morales, DR; Wang, JX | 1 |
| Adams, ZF; Cole, NW; Miller, RR; Walcher, BN; Weaver, KR | 1 |
| Anderstam, B; Axelsson, J; Bárány, P; Carrero, JJ; Garibotto, G; Lindholm, B; Qureshi, AR; Stenvinkel, P; Suliman, ME; Valli, A | 1 |
| Chen, G; Liang, QL; Luo, GA; Song, XM; Wang, Y; Wang, YM; Wu, JX; Yang, HH; Zhang, HY; Zhang, T; Zheng, XY | 1 |
| Kohlwein, SD; Malanovic, N; Rechberger, G; Streith, I; Tehlivets, O; Wolinski, H | 1 |
| Han, T; James, SR; Karpf, AR; Melnyk, S; Pogribny, IP; Tryndyak, VP | 1 |
| Allen, RH; Carvalho, FR; Guerra-Shinohara, EM; Hirata, MH; Hirata, RD; Lopreato, FR; Robi, DL; Sampaio-Neto, LF; Stabler, SP | 1 |
| Blom, H; Linnebank, M; Moskau, S; Semmler, A; Smith, D; Smulders, Y; Struys, E | 1 |
| Garcia, P; Herrmann, M; Herrmann, W; Hübner, U; Ross, S; Schorr, H; Taban-Shomal, O; Umanskaya, N; Wagner, A; Wildemann, B; Wolny, M | 1 |
| Garcia, P; Herrmann, M; Herrmann, W; Hübner, U; Ross, S; Schorr, H; Taban-Shomal, O; Tami, A; Umanskaya, N; Wagner, A; Wildemann, B; Wolny, M | 1 |
| Kawakami, Y; Morita, T; Ohuchi, S; Sugiyama, K | 1 |
| Kharbanda, KK | 1 |
| Mori, M; Morita, T; Ohuchi, S; Sugiyama, K | 1 |
| Dai, Y; Lu, X; Pei, L; Yin, Y; Zhang, T; Zheng, X | 1 |
| Dillmann, U; Fassbender, K; Herrmann, W; Kostopoulos, P; Obeid, R; Schadt, A | 1 |
| Hu, ML; Lin, HC; Liu, CL; Yang, CM | 1 |
| de Jonge, R; de Vries, JH; Eijkemans, MJ; Steegers, EA; Steegers-Theunissen, RP; van Driel, LM; van Meurs, JB | 1 |
| Barone, P; De Bonis, ML; Galletti, P; Ingrosso, D; Longo, K; Pellecchia, MT; Russo, A; Salvatore, A; Tedeschi, G; Tessitore, A; Zappia, V | 1 |
| Ling, W; Mi, M; Yu, X | 1 |
| Devlin, AM; Green, TJ; Innis, SM; McMahon, JA; Skeaff, CM; Venn, BJ; Williams, SM | 1 |
| Jang, Y; Kwon, YH; Park, YJ | 1 |
| Capecci, LM; Chen, NC; Durante, W; Gu, Z; Schafer, AI; Wang, H; Yang, F; Yang, XF | 1 |
| Chang, PY; Chen, CH; Lu, SC | 1 |
| Garrow, TA; Gupta, S; Jiracek, J; Kruger, WD; Li, L; Rozen, R; Schalinske, KL; Strakova, J; Williams, KT | 1 |
| Chang, PY; Chen, YJ; Lu, SC | 1 |
| Wagner, C | 1 |
| Chen, SY; Chen, YM; Chiang, EP; Tang, FY; Wang, YC | 1 |
| Garcia, P; Herrmann, M; Herrmann, W; Histing, T; Holstein, JH; Klein, M; Kurz, K; Menger, MD; Pohlemann, T; Siebel, T; Splett, C | 1 |
| de Jonge, R; de Vries, JH; Looman, CW; Obermann-Borst, SA; Steegers, EA; Steegers-Theunissen, RP; Vujkovic, M; Wildhagen, MF | 1 |
| Benight, NM; Burrin, DG; Chacko, S; da Silva, VR; Gregory, JF; Marini, JC; Stabler, SP; Stoll, B | 1 |
| Hahn, NE; Krijnen, PA; Meischl, C; Musters, RJ; Niessen, HW; Rauwerda, JA; Sipkens, JA; Smith, DE; Stehouwer, CD; van Hinsbergh, VW; Wassink, M | 1 |
| Balasubramaniam, S; Bjursell, MK; Blom, HJ; Brandberg, G; Cayuela, JA; Engvall, ML; Falkenberg, M; Gustafsson, CM; Halldin, M; Jakobs, C; Lesko, N; Lundeberg, J; Smith, D; Struys, E; von Döbeln, U; Wedell, A | 1 |
| Blom, HJ; Hahn, NE; Krijnen, PA; Lougheed, SM; Niessen, HW; Rauwerda, JA; Sipkens, JA; Stehouwer, CD; van Hinsbergh, VW | 1 |
| Kim, BH; Kim, CH; Kim, SK; Lee, CH; Lee, HS; Lee, KS; Oh, JM; Ryu, CS; Yun, KU | 1 |
| de Jonge, R; Enneman, AW; Heil, SG; Hofman, A; Rivadeneira, F; Stolk, L; Uitterlinden, AG; van der Velde, N; van Meurs, JB; Zillikens, MC | 1 |
| Casson, RI; Dodds, L; Ho, V; King, WD; Massey, TE; Perkins, SL | 1 |
| Alpert, JE; Arning, E; Bottiglieri, T; Fava, M; Mischoulon, D; Papakostas, GI | 1 |
| Beurskens, LW; de Jonge, R; Schoonderwaldt, EM; Steegers-Theunissen, RP; Tibboel, D | 1 |
| Blom, HJ; Farkas, M; Jessen, F; Linnebank, M; Popp, J; Semmler, A; Smith, DE; Smulders, YM | 1 |
| Gong, H; Jiang, Y; Shi, Y; Sun, T; Sun, W; Wang, J; Wei, J; Yang, B; Zhang, H | 1 |
| Hamada, K; Hudec, R; Mikoshiba, K | 1 |
| Caudill, M; Jiang, X; Mikael, LG; Pancer, J; Rozen, R; Wu, Q | 1 |
| Aleliunas, RE; Bottiglieri, T; Devlin, AM; Glier, MB; Ngai, YF; Sulistyoningrum, DC | 1 |
| Bodis, M; Geisel, J; Herrmann, W; Hübner, U; Kirsch, SH; Klein, C; Kruse, V; Obeid, R | 1 |
| Bloom, L; Desiderio, DM; Gardner, LA; Groover, CJ; Hartzes, A; Levin, MC; Yates, CR; Zucker-Levin, AR | 1 |
| Bigler, L; Blom, H; Linnebank, M; Prost, JC; Semmler, A; Smith, D; Smulders, Y | 1 |
| Cole, D; Cox, SE; da Costa, KA; Dominguez-Salas, P; Dyer, RA; Fulford, AJ; Hennig, BJ; Innis, SM; Moore, SE; Prentice, AM; Waterland, RA; Zeisel, SH | 1 |
| Chen, YM; Chiang, EP; Lin, WL; Lin, YJ; Tang, FY; Wang, YC | 1 |
| Ahumada, V; Arraztoa, JA; Bustos, V; Dobierzewska, A; España-Perrot, PP; Fernández, XB; Figueroa-Diesel, H; Illanes, SE; Pérez-Sepúlveda, A; Rice, GE | 1 |
| Adachi, S; Heike, T; Kubota, M; Nakata, R; Shima, M; Takeshita, Y; Watanabe, K | 1 |
| Dekker, JM; Drevon, CA; Elshorbagy, AK; Nijpels, G; Nurk, E; Nygård, O; Refsum, H; Stehouwer, CD; Teerlink, T; Tell, GS; Ueland, PM; Vinknes, KJ; Vollset, SE | 1 |
| Li, Q; Mao, L; Wang, R; Xue, L; Zhu, L | 1 |
| Blom, HJ; Castro, R; Davids, M; Esse, R; Florindo, C; Gupta, S; Imbard, A; Kruger, WD; Quinlivan, EP; Tavares de Almeida, I; Teerlink, T | 1 |
| Berg, JT; Fliser, D; Friedrich, A; Geisel, J; Heine, GH; Hummel, B; Obeid, R; Rogacev, KS; Roth, HJ; Zawada, AM | 1 |
| Alam, S; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Liu, X; Niedzwiecki, MM; Siddique, AB; Slavkovich, V | 1 |
| Agamme, AL; D'Almeida, V; da Silva, VC; Fernandes, L; Guerra Shinohara, EM; Haseyama, EJ; Muniz, MT | 1 |
| Barroso, M; Blom, HJ; Carlson, BA; Castro, R; de Almeida, IT; Florindo, C; Gladyshev, VN; Handy, DE; Hatfield, DL; Kalwa, H; Loscalzo, J; Michel, T; Silva, Z; Turanov, AA | 1 |
| Converso, A; Fraley, ME; Garbaccio, RM; Hartingh, T; Hartman, GD; Huang, SY; Majercak, JM; McCampbell, A; Na, SJ; Ray, WJ; Savage, MJ; White, R; Wolffe, C; Yeh, S; Yu, Y; Zhang, R | 1 |
| Cao, CJ; Han, XB; Jiang, YD; Tian, J; Wang, J; Wang, YH; Xu, H; Yang, AN; Yang, XL; Zhang, HP | 1 |
| French, SW; Kharbanda, KK; Orlicky, DJ; Osna, NA; Thomes, PG; Todero, SL; Tuma, DJ | 1 |
| Guan, Z; Niu, B; Wang, J; Wang, X; Wang, Z; Xie, Q; Zhang, T; Zhao, X; Zhu, Z | 1 |
| Comparotto, H; Deminice, R; Jordao, AA | 1 |
| Akyuz, M; Bakan, N; Boyuk, A; Cikman, O; Gumustekin, K; Keles, MS; Taysi, S | 1 |
| Blanco-González, E; Cinti, M; Fernández de la Campa, MR; Iglesias González, T; Montes-Bayón, M | 1 |
| Kim, SK; Kim, YM; Kwak, HC; Oh, SJ | 1 |
| Bodis, M; Geisel, J; Herrmann, M; Herrmann, W; Hübner, U; Kirsch, SH; Laufs, U; Pusceddu, I; Wagenpfeil, S; Werner, C | 1 |
| Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Islam, T; Liu, X; Parvez, F; Peters, BA; Shahriar, H; Siddique, AB; Uddin, MN | 1 |
| Imiolczyk, B; Jaskolski, M; Manszewski, T; Singh, K | 1 |
| Chan, K; Kam, A; Razmovski-Naumovski, V; Troung, J; Zhou, X | 1 |
| Cao, J; Guo, X; He, Y; Jiang, Y; Kong, F; Liu, Z; Ma, S; Tian, J; Wang, Y; Xu, H; Yang, A; Yang, X; Zhang, H; Zhang, M | 1 |
| Andrews, AJ; Gupta, S; Kruger, WD; Kuo, YM; Lee, HO; Li, YS; Slifker, MJ; Wang, L | 1 |
| Bertolo, RF; Brunton, JA; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Apostolakos, MJ; Arning, E; Bottiglieri, T; Doolin, KP; Gough, MS; Mack, CM; Mooney, RA; Morgan, MAM; Pietropaoli, AP; Wexler, O | 1 |
| Augoustides-Savvopoulou, P; Barić, I; Blom, HJ; Chien, YH; Dobbelaere, D; Grünert, SC; Opladen, T; Petković Ramadža, D; Rakić, B; Staufner, C; Wedell, A | 1 |
| Feng, D; French, SW; Ganesan, M; Kharbanda, KK; Maillacheruvu, PF; Orlicky, DJ; Osna, NA; Tuma, DJ | 1 |
| Bertinetti, D; Herberg, FW; Kailing, LL; Pavlidis, IV | 1 |
| Cao, JC; He, YY; Jia, YX; Jiang, YD; Jiao, Y; Jin, SJ; Lu, GJ; Ma, SC; Tian, J; Wang, YH; Yang, AN; Yang, XL; Yang, XM; Zhang, H; Zhang, HP; Zhang, MH | 1 |
| Cella, PS; da Silva, LECM; Deminice, R; Jordao, AA; Riberio, DF | 1 |
| Blom, HJ; Castro, R; Esse, R; Koolwijk, P; Tavares de Almeida, I; Teerlink, T | 1 |
| Huse, K; Olecka, M; Platzer, M | 1 |
| Fan, L; Li, D; Li, L; Liang, S; Sun, C; Sun, Y; Wu, L; Xia, W; Zou, M | 1 |
| Coalson, DW; Douglas Wallace, C; Erbe, RW; Hoffman, RM; Stern, PH | 1 |
| Barroso, M; Castro, R; Esse, R; Tavares de Almeida, I | 1 |
| Bulgakova, PO; Fedoseev, AN; Grachev, SV; Ivanov, AV; Kruglova, MP; Kubatiev, AA; Samokhin, AS; Virus, ED | 1 |
| Kane, MA; Li, J; Liu, T; Petri, MA; Stojan, G | 1 |
| Arning, E; Bottiglieri, T; Collado, MC; Demerath, EW; Fields, DA; Isganaitis, E; Lerin, C; Wasek, B | 1 |
| Bito, T; Ishihara, A; Iwasaki, R; Watanabe, F; Yabuta, Y | 1 |
| Hou, Q; Lin, B; Ruan, Y; Xiang, L; Yuan, Z; Zhang, J | 1 |
15 review(s) available for homocysteine and s-adenosylhomocysteine
| Article | Year |
|---|---|
Metabolism of sulfur-containing amino acids.
Topics: Adenosylhomocysteinase; Animals; Carboxy-Lyases; Cysteine; Female; Homocysteine; Humans; Hydrolases; Isoenzymes; Liver; Male; Methionine; Methionine Adenosyltransferase; Methylation; Polyamines; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Taurine; Transaminases | 1986 |
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1984 |
Pharmacological and biochemical aspects of S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Catalysis; Chemical Phenomena; Chemistry, Physical; Genes; Homocysteine; Humans; Hydrolases; Kinetics; Protein Binding; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; S-Adenosylhomocysteine; Substrate Specificity; Tubercidin | 1982 |
Membrane protein damage and methylation reactions in chronic renal failure.
Topics: Homocysteine; Humans; Kidney Failure, Chronic; Membrane Proteins; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; S-Adenosylhomocysteine; Substrate Specificity | 1996 |
Pathways and regulation of homocysteine metabolism in mammals.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Heme; Homocysteine; Isoenzymes; Kinetics; Mammals; Methionine; Methionine Adenosyltransferase; Organ Specificity; Oxidation-Reduction; Pyridoxal Phosphate; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tetrahydrofolates | 2000 |
Homocysteine, coagulation, platelet function, and thrombosis.
Topics: Adolescent; Adult; Arteriosclerosis; Blood Coagulation; Cardiovascular Diseases; Cellular Senescence; Child; Endothelium, Vascular; Female; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Lipoproteins, LDL; Male; Methyltransferases; Oxidation-Reduction; Platelet Activation; Reactive Oxygen Species; Renal Insufficiency; Risk Factors; S-Adenosylhomocysteine; Thrombophilia; Thromboxane B2; Vitamin K | 2000 |
On the mechanism of homocysteine pathophysiology and pathogenesis: a unifying hypothesis.
Topics: Animals; Cardiovascular Diseases; Catechol O-Methyltransferase Inhibitors; Catecholamines; Homocysteine; Humans; S-Adenosylhomocysteine | 2002 |
Biomarkers of nutrient exposure and status in one-carbon (methyl) metabolism.
Topics: Biomarkers; Carbon; Diet; DNA Methylation; Folic Acid; Homocysteine; Humans; Methylation; Nutritional Status; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B Complex | 2003 |
Potential role for adenosine in the pathogenesis of the vascular complications of hyperhomocysteinemia.
Topics: Adenosine; Cardiovascular Diseases; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Receptors, Purinergic P1; S-Adenosylhomocysteine | 2003 |
S-adenosylmethionine and its products.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Glycine N-Methyltransferase; Homocysteine; Humans; Liver; Methionine Adenosyltransferase; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
S-Adenosylhomocysteine: a better indicator of vascular disease than homocysteine?
Topics: Homocysteine; Humans; S-Adenosylhomocysteine; Vascular Diseases | 2007 |
Alcoholic liver disease and methionine metabolism.
Topics: Alcohol Drinking; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Ethanol; Homocysteine; Humans; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 2009 |
Homocysteine, iron and cardiovascular disease: a hypothesis.
Topics: Biomarkers; Cardiovascular Diseases; Cystathionine; Dietary Supplements; Folic Acid; Free Radicals; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Lipoproteins, LDL; Methionine; Risk Factors; S-Adenosylhomocysteine; Vitamin B Complex | 2015 |
Consensus recommendations for the diagnosis, treatment and follow-up of inherited methylation disorders.
Topics: Consensus; Homocysteine; Humans; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methionine Adenosyltransferase; Methylation; Neonatal Screening; S-Adenosylhomocysteine; S-Adenosylmethionine | 2017 |
The Contribution of Homocysteine Metabolism Disruption to Endothelial Dysfunction: State-of-the-Art.
Topics: Atherosclerosis; Cardiovascular Diseases; Endothelial Cells; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Methionine; Nitric Oxide; Reactive Oxygen Species; S-Adenosylhomocysteine | 2019 |
10 trial(s) available for homocysteine and s-adenosylhomocysteine
| Article | Year |
|---|---|
Metabolic consequences of folate-induced reduction of hyperhomocysteinemia in uremia.
Topics: Erythrocyte Membrane; Homocysteine; Humans; Membrane Proteins; Methionine; Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Uremia | 1997 |
Measurement of plasma and intracellular S-adenosylmethionine and S-adenosylhomocysteine utilizing coulometric electrochemical detection: alterations with plasma homocysteine and pyridoxal 5'-phosphate concentrations.
Topics: Adult; Chromatography, High Pressure Liquid; Electrochemistry; Female; Homocysteine; Humans; Indicators and Reagents; Liver; Lymphocytes; Middle Aged; Pyridoxal Phosphate; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Sensitivity and Specificity; Trichloroacetic Acid | 2000 |
Blood S-adenosylmethionine concentrations and lymphocyte methylenetetrahydrofolate reductase activity in diabetes mellitus and diabetic nephropathy.
Topics: Adult; Albuminuria; Creatinine; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Disease Progression; Erythrocytes; Female; Homocysteine; Humans; Lymphocytes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Reference Values; Regression Analysis; Renal Dialysis; S-Adenosylhomocysteine; S-Adenosylmethionine | 2001 |
Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia.
Topics: Acetylcysteine; Adult; Arginine; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Cystathionine; Cysteine; Dipeptides; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Male; Methionine; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vasodilation | 2005 |
Tolcapone decreases plasma levels of S-adenosyl-L-homocysteine and homocysteine in treated Parkinson's disease patients.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benzophenones; Catechol O-Methyltransferase Inhibitors; Enzyme Inhibitors; Female; Homocysteine; Humans; Levodopa; Male; Middle Aged; Nitrophenols; Parkinson Disease; Prospective Studies; S-Adenosylhomocysteine; Tolcapone | 2006 |
Iron-dependent formation of homocysteine from methionine and other thioethers.
Topics: Adult; Area Under Curve; Cross-Over Studies; Cystathionine; Female; Homocysteine; Humans; Hydrogen-Ion Concentration; Iron; Iron Chelating Agents; Male; Methionine; S-Adenosylhomocysteine | 2007 |
Homocysteine-lowering vitamins do not lower plasma S-adenosylhomocysteine in older people with elevated homocysteine concentrations.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vascular Diseases; Vitamin B 12; Vitamin B 6; Vitamins | 2010 |
Bioavailability of S-adenosyl methionine and impact on response in a randomized, double-blind, placebo-controlled trial in major depressive disorder.
Topics: Biological Availability; Depressive Disorder, Major; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Psychiatric Status Rating Scales; S-Adenosylhomocysteine; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Tetrahydrofolates | 2012 |
Effect of 1 year B and D vitamin supplementation on LINE-1 repetitive element methylation in older subjects.
Topics: Aged; Aged, 80 and over; Calcium Carbonate; Cholecalciferol; Dietary Supplements; DNA Methylation; Drug Administration Schedule; Female; Homocysteine; Humans; Long Interspersed Nucleotide Elements; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B Complex | 2013 |
Low-Dose Creatine Supplementation Lowers Plasma Guanidinoacetate, but Not Plasma Homocysteine, in a Double-Blind, Randomized, Placebo-Controlled Trial.
Topics: Adult; Bangladesh; Biomarkers; Cohort Studies; Creatine; Dietary Supplements; Double-Blind Method; Down-Regulation; Female; Folic Acid; Glycine; Homocysteine; Humans; Hyperhomocysteinemia; Intention to Treat Analysis; Male; Middle Aged; Patient Dropouts; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
380 other study(ies) available for homocysteine and s-adenosylhomocysteine
| Article | Year |
|---|---|
Purification and properties of S-adenosyl-L-homocysteine hydrolase from leaves of spinach beet.
Topics: Adenine; Cysteine; Deoxyadenosines; Homocysteine; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Methionine; Plants; S-Adenosylhomocysteine; S-Adenosylmethionine | 1976 |
[Effect of S-adenosyl-L-homocysteine of dopamine catabolism].
Topics: Animals; Brain; Corpus Striatum; Deoxyepinephrine; Dopamine; Homocysteine; Hypothalamus; Male; Methyltransferases; Norepinephrine; Normetanephrine; Organ Specificity; Rats; S-Adenosylhomocysteine; Thalamus | 1979 |
S-Adenosyl-L-homocysteine and structurally related molecules: synthesis and analysis of the carbon-13 nuclear magnetic resonance spectra [proceedings].
Topics: Homocysteine; Magnetic Resonance Spectroscopy; Molecular Conformation; S-Adenosylhomocysteine; Structure-Activity Relationship | 1979 |
Inhibition of protein methyltransferases II from human erythrocytes by S-adenosyl-L-homocysteine and structurally related molecules [proceedings].
Topics: Erythrocytes; Homocysteine; Humans; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylhomocysteine; Structure-Activity Relationship | 1979 |
[Effects of S-adenosylmethionine and S-adenosylhomocysteine on in vivo synthesis of noradrenaline and serotonin in different parts of the rat brain].
Topics: Animals; Brain; Homocysteine; Norepinephrine; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Serotonin | 1979 |
Deficiency of S-adenosylmethionine-homocysteine methyltransferase activity in hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Female; Homocysteine; Hydrolases; Liver; Liver Neoplasms; Methyltransferases; Neoplasms, Experimental; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1977 |
Giant heterogeneous polyadenylic acid on vesicular stomatitis virus mRNA synthesized in vitro in the presence of S-adenosylhomocysteine.
Topics: Cell-Free System; Homocysteine; Methylation; Poly A; RNA-Dependent RNA Polymerase; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; Transcription, Genetic; Vesicular stomatitis Indiana virus | 1977 |
Inhibition of viral RNA methylation in herpes simplex virus type 1-infected cells by 5' S-isobutyl-adenosine.
Topics: Cell Line; Homocysteine; Methylation; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; Simplexvirus; Viral Proteins; Virus Replication | 1977 |
Decreased rate of S-adenosyl-L-homocysteine metabolism: an early event related to transformation in cells infected with Rous sarcoma virus.
Topics: Adenosine; Adenosine Deaminase; Amino Acid Oxidoreductases; Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Homocysteine; Hydrolases; Methylation; Neoplasm Proteins; Proteins; S-Adenosylhomocysteine; Tumor Virus Infections | 1977 |
In vivo inhibition of Novikoff cytoplasmic messenger RNA methylation by S-tubercidinylhomocysteine.
Topics: Carcinoma, Hepatocellular; Cell Line; Homocysteine; Liver Neoplasms; Neoplasms, Experimental; Oligoribonucleotides; Poly A; RNA, Messenger; S-Adenosylhomocysteine | 1977 |
Adenosylhomocysteine hydrolase inhibitors: synthesis of 5'-deoxy-5'-(isobutylthio)-3-deazaadenosine and its effect on Rous sarcoma virus and Gross murine leukemia virus.
Topics: AKR murine leukemia virus; Antiviral Agents; Avian Sarcoma Viruses; Cell Transformation, Viral; Homocysteine; Hydrolases; Kinetics; S-Adenosylhomocysteine; Structure-Activity Relationship; Tubercidin; Virus Replication | 1978 |
Inhibition of virus-induced cell transformation by synthetic analogues of S-adenosyl homocysteine.
Topics: Adenosine; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Fibroblasts; Homocysteine; S-Adenosylhomocysteine; Time Factors; Virus Replication | 1975 |
An adenosine 3':5'-monophosphate adenosine-binding protein from mouse liver. Association with S-adenosylhomocysteinase activity.
Topics: Adenosine; Animals; Carrier Proteins; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Homocysteine; Hydrolases; Hydrolysis; Liver; Mice; S-Adenosylhomocysteine | 1978 |
Inhibition of lymphocyte-mediated cytolysis by 3-deazaadenosine: evidence for a methylation reaction essential to cytolysis.
Topics: Cyclic AMP; Cytotoxicity, Immunologic; Homocysteine; Immunity, Cellular; Isomerism; Methyltransferases; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine; T-Lymphocytes; Tubercidin | 1978 |
S-adenosylhomocysteine toxicity in normal and adenosine kinase-deficient lymphoblasts of human origin.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Cell Division; Cell Line; Homocysteine; Humans; Lactones; Lymphocytes; Methylation; Phosphotransferases; S-Adenosylhomocysteine | 1979 |
Cyclic AMP-adenosine binding protein/S-adenosylhomocysteinase from mouse liver. A fraction of adenosine bound is converted to adenine.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Carrier Proteins; Chromatography, Gel; Chromatography, Thin Layer; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Homocysteine; Hydrolases; Hydrolysis; In Vitro Techniques; Inosine; Liver; Mice; Protein Denaturation; Ribose; S-Adenosylhomocysteine | 1979 |
Relationship between inhibition of protein methylase I and inhibition of Rous sarcoma virus-induced cell transformation.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Fibroblasts; Homocysteine; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; S-Adenosylhomocysteine; Structure-Activity Relationship | 1979 |
[Effect of 5-deoxy-5-S-isobutyladenosine on the synthesis and methylation of DNA in mouse lympholeukemia cells and human lymphocytes].
Topics: Animals; Antineoplastic Agents; Cell Line; Deoxyadenosines; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Homocysteine; Humans; Leukemia, Experimental; Leukemia, Lymphoid; Lymphocyte Activation; Lymphocytes; Mice; S-Adenosylhomocysteine; Thionucleosides | 1979 |
"Pretranscriptional capping" in the biosynthesis of cytoplasmic polyhedrosis virus mRNA.
Topics: Adenylyl Imidodiphosphate; Base Sequence; Guanine Nucleotides; Homocysteine; Insect Viruses; Methylation; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcription, Genetic | 1978 |
S-adenosyl-L-homocysteine as a stimulator of viral RNA synthesis by two distinct cytoplasmic polyhedrosis viruses.
Topics: Adenosine; Cell-Free System; Homocysteine; Insect Viruses; Methylation; RNA, Messenger; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; Stimulation, Chemical | 1978 |
Escherichia coli tRNA (uracil-5-)-methyltransferase: Inhibition by analogues of adenosylhomocysteine.
Topics: Amino Acids; Binding Sites; Escherichia coli; Homocysteine; S-Adenosylhomocysteine; Structure-Activity Relationship; tRNA Methyltransferases | 1979 |
Relationship between tissue levels of S-adenosylmethionine, S-adenylhomocysteine, and transmethylation reactions.
Topics: Aging; Animals; Female; Homocysteine; Liver; Methylation; Methyltransferases; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1979 |
Metabolism of S-adenosylhomocysteine and S-tubercidinylhomocysteine in neuroblastoma cells.
Topics: Animals; Cell Line; Chromatography, High Pressure Liquid; Homocysteine; Kinetics; Neuroblastoma; S-Adenosylhomocysteine | 1979 |
Inhibition of methylation by adenosine in adenosine deaminase-inhibited, phytohemagglutinin-stimulated human lymphocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; DNA; Homocysteine; Humans; Lymphocyte Activation; Methylation; Nucleoside Deaminases; Phytohemagglutinins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1979 |
Binding capacities of various analogues of S-adenosyl-L-homocysteine to protein methyltransferase II from human erythrocytes.
Topics: Erythrocytes; Homocysteine; Humans; Protein Binding; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylhomocysteine; Structure-Activity Relationship | 1979 |
Activation by S-adenosylhomocysteine of norepinephrine and serotonin in vitro uptake in synaptosomal preparations from rat brain.
Topics: Animals; Biological Transport; Brain; Dopamine; Homocysteine; Kinetics; Male; Norepinephrine; Rats; S-Adenosylhomocysteine; Serotonin; Synaptosomes | 1979 |
Action of S-adenosyl-L-homocysteine on the metabolism of dopamine, norepinephrine and serotonin in rat brain.
Topics: Animals; Brain; Dopamine; Dose-Response Relationship, Drug; Homocysteine; Male; Norepinephrine; Rats; S-Adenosylhomocysteine; Serotonin; Time Factors | 1979 |
Effect of S-adenosylhomocysteine and S-tubercidinylhomocysteine on catecholamine methylation in neuroblastoma cells.
Topics: Animals; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cells, Cultured; Dopamine; Homocysteine; Methylation; Mice; Neuroblastoma; S-Adenosylhomocysteine | 1977 |
The relation between purine metabolism and flavinogenesis in Eremothecium ashbyii. The identification of S-adenosylmethionine and S-adenosylhomocysteine accumulated in non-growing cells of E. ashbyii.
Topics: Adenine; Ascomycota; Culture Media; Dose-Response Relationship, Drug; Homocysteine; Riboflavin; S-Adenosylhomocysteine; S-Adenosylmethionine; Saccharomycetales | 1977 |
Tissue distribution of S-adenosylmethionine and S-adenosylhomocysteine in the rat. Effect of age, sex and methionine administration on the metabolism of S-adenosylmethionine, S-adenosylhomocysteine and polyamines.
Topics: Age Factors; Animals; Brain; Glycine; Homocysteine; Hydrolases; Kidney; Liver; Methionine; Methionine Adenosyltransferase; Polyamines; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors | 1977 |
Role of S-adenosylhomocysteine in adenosinemediated toxicity in cultured mouse T lymphoma cells.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Cell Line; DNA; DNA (Cytosine-5-)-Methyltransferases; Homocysteine; Homocystine; Lymphoma; S-Adenosylhomocysteine | 1977 |
A sensitive enzymatic procedure for the quantitative determination of S-adenosylhomocysteine in tissues.
Topics: Animals; Catechol O-Methyltransferase Inhibitors; Homocysteine; Liver; Male; Methods; Rats; S-Adenosylhomocysteine | 1978 |
Biosynthesis of S-N6-methyladenosylhomocysteine, an inhibitor of RNA methyltransferases.
Topics: Animals; Homocysteine; Hydrolases; Liver; Mice; S-Adenosylhomocysteine; tRNA Methyltransferases | 1978 |
Differential inhibition of mammalian aminopropyltransferase activities.
Topics: Adenosine; Animals; Diamines; Ethionine; Homocysteine; Male; Prostate; Rats; S-Adenosylhomocysteine; Spermidine Synthase; Spermine Synthase; Thionucleosides; Transferases | 1978 |
Protein methylation in animal cells. II. Inhibition of S-adenosyl-L-methionine:protein(arginine) N-methyltransferase by analogs of S-adenosyl-L-homocysteine.
Topics: Adenosine; Binding Sites; Homocysteine; Isomerism; Kinetics; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; S-Adenosylhomocysteine; Structure-Activity Relationship | 1978 |
S-adenosylhomocysteine analogues as inhibitors of specific tRNA methylation.
Topics: Animals; Homocysteine; Kinetics; Liver; Male; Rats; S-Adenosylhomocysteine; Structure-Activity Relationship; tRNA Methyltransferases | 1978 |
Inhibition of methyltransferases by some new analogs of S-adenosylhomocysteine.
Topics: Adrenal Glands; Animals; Brain; Guinea Pigs; Homocysteine; In Vitro Techniques; Liver; Methyltransferases; Rabbits; Rats; S-Adenosylhomocysteine | 1978 |
Affinity labeling of histamine N-methyltransferase by 2',3'-dialdehyde derivatives of S-adenosylhomocysteine and S-adenosylmethionine. Kinetics of inactivation.
Topics: Affinity Labels; Chemical Phenomena; Chemistry; Histamine N-Methyltransferase; Homocysteine; Kinetics; Magnetic Resonance Spectroscopy; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrophotometry, Infrared; Structure-Activity Relationship | 1978 |
S-adenosylhomocysteine metabolism in rat hepatomas.
Topics: Animals; Dietary Proteins; Homocysteine; Liver; Liver Neoplasms, Experimental; Male; Methyltransferases; Rats; S-Adenosylhomocysteine | 1978 |
Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 7. Role of the ribosyl moiety in enzymatic binding of S-adenosyl-L-homocysteine and S-adenosyl-L-methionine.
Topics: Animals; Cattle; Guinea Pigs; Homocysteine; In Vitro Techniques; Male; Methods; Methyltransferases; Oxidation-Reduction; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1978 |
[New studies on inhibition of tRNA N2 guanine methyltransferase by S-adenosyl-homocysteine and S-adenosyl-methionine analogs].
Topics: Animals; Escherichia coli; Guanine; Homocysteine; Kinetics; Liver; Rabbits; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; tRNA Methyltransferases | 1976 |
The effect of S-adenosylhomocysteine on DNA methylation in isolated rat liver nuclei.
Topics: Animals; Cell Nucleus; DNA; Dose-Response Relationship, Drug; Homocysteine; Liver; Liver Regeneration; Male; Methylation; Rats; S-Adenosylhomocysteine | 1977 |
Species and tissue differences in the catabolism of S-adenosyl-L-homocysteine: a quantitative, chromatographic study.
Topics: Adenine; Animals; Brain; Chromatography, High Pressure Liquid; Homocysteine; Hydrolases; Hypoxanthines; Inosine; Kidney; Liver; Male; Mice; Rats; S-Adenosylhomocysteine; Species Specificity; Uric Acid; Xanthines | 1977 |
S-Adenosyl-L-homocysteine hydrolase: analogues of S-adenosyl-L-homocysteine as potential inhibitors.
Topics: Animals; Cattle; Homocysteine; Hydrolases; In Vitro Techniques; Liver; Male; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1977 |
Inhibition of Newcastle disease virion messenger RNA (guanine-7-)-methyltransferase by analogues of S-adenosylhomocysteine.
Topics: Guanine; Homocysteine; Newcastle disease virus; S-Adenosylhomocysteine; Structure-Activity Relationship; tRNA Methyltransferases | 1977 |
The enzymatic synthesis of S-adenosyl-L-[2(n)-3H]homocysteine.
Topics: Animals; Glycine; Homocysteine; Hydrolases; Liver; Methyltransferases; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1977 |
S-adenosyl-L-homocysteine dialdehyde: an affinity labeling reagent for histamine-N-methyltransferase.
Topics: Affinity Labels; Animals; Binding Sites; Brain; Guinea Pigs; Histamine N-Methyltransferase; Homocysteine; Kinetics; Mathematics; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1977 |
[New syntheses of S-adenosylhomocysteine and S-adenosylmethionine analogs].
Topics: Homocysteine; Methods; S-Adenosylhomocysteine; S-Adenosylmethionine | 1976 |
Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 4. Further modifications of the amino and base portions of S-adenosyl-L-homocysteine.
Topics: Animals; Binding Sites; Cattle; Guinea Pigs; Homocysteine; In Vitro Techniques; Male; Methyltransferases; Rabbits; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1976 |
A new method for the assay of tissue. S-adenosylhomocysteine and S-adenosylmethione. Effect of pyridoxine deficiency on the metabolism of S-adenosylhomocysteine, S-adenosylmethionine and polyamines in rat liver.
Topics: Adenosylmethionine Decarboxylase; Animals; Chromatography; Homocysteine; Liver; Male; Polyamines; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Vitamin B 6 Deficiency | 1976 |
Inhibition of indolethylamine-N-methyltransferase by analogs of S-adenosylhomocysteine.
Topics: Animals; Homocysteine; In Vitro Techniques; Indoles; Kinetics; Lung; Methyltransferases; Rabbits; S-Adenosylhomocysteine; Structure-Activity Relationship | 1975 |
A rapid liquid chromatographic determination of S-adenosylhomocysteine in subgram amounts of tissue.
Topics: Animals; Chromatography, High Pressure Liquid; Ethionine; Female; Homocysteine; Liver; Mice; Mice, Inbred C57BL; Microchemistry; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1975 |
Effect of S-adenosylhomocysteine and S-tubercidinylhomocysteine on transfer ribonucleic acid methylation in phytohemagglutinin-stimulated lymphocytes.
Topics: Animals; DNA; Homocysteine; In Vitro Techniques; Lectins; Lymphocyte Activation; Lymphocytes; Male; Methylation; Rats; Rats, Inbred Strains; RNA, Transfer; S-Adenosylhomocysteine; Tubercidin | 1975 |
S-adenosylhomocysteine inhibition of three purified tRNA methyltransferases from rat liver.
Topics: Adenine; Animals; Guanine; Homocysteine; Isoenzymes; Kinetics; Liver; Male; Rats; S-Adenosylhomocysteine; Structure-Activity Relationship; tRNA Methyltransferases | 1975 |
A convenient preparation of S-adenosylhomocysteine and related compounds.
Topics: Deoxyribonucleosides; Homocysteine; Methods; S-Adenosylhomocysteine | 1976 |
S-Aristeromycinyl-L-homocysteine, a potent inhibitor of S-adenosylmethionine-dependent transmethylations.
Topics: Acetylserotonin O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Depression, Chemical; Histamine N-Methyltransferase; Homocysteine; Kinetics; Phenylethanolamine N-Methyltransferase; S-Adenosylhomocysteine | 1976 |
Analogues of S-adenosylhomocysteine as potential inhibitors of biological transmethylation. Synthesis of analogues with modifications at the 5'-thioether linkage.
Topics: Alkylation; Catechol O-Methyltransferase Inhibitors; Homocysteine; Methylation; S-Adenosylhomocysteine; Structure-Activity Relationship; tRNA Methyltransferases | 1976 |
S-adenosylhomocysteine levels are not involved in the spasmolytic activity of 3-deazaadenosine in guinea-pig lung parenchyma.
Topics: Adenosine; Animals; Cyclic AMP; Cyclic GMP; Guinea Pigs; Homocysteine; In Vitro Techniques; Lung; Male; Parasympatholytics; S-Adenosylhomocysteine; SRS-A; Tubercidin | 1991 |
Mechanism of antiviral and cytotoxic action of (+/-)-6' beta-fluoroaristeromycin, a potent inhibitor of S-adenosylhomocysteine hydrolase.
Topics: Adenine; Adenosylhomocysteinase; Animals; Antiviral Agents; Cell Division; Homocysteine; Hydrolases; Mice; Nucleic Acids; Phosphorylation; Protein Biosynthesis; S-Adenosylhomocysteine; S-Adenosylmethionine | 1991 |
Mechanism of the synergistic antiviral and cytostatic activity of (RS)-3-(adenin-9-yl)-2-hydroxypropanoic acid isobutyl ester and D,L-homocysteine.
Topics: Adenine; Adenosylhomocysteinase; Animals; Antiviral Agents; Cell Line; Drug Synergism; Homocysteine; Hydrolases; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Vaccinia virus | 1990 |
Cobalamin neuropathy. Is S-adenosylhomocysteine toxicity a factor?
Topics: Animals; Brain Chemistry; Chiroptera; Chromatography, High Pressure Liquid; Homocysteine; Liver; Methionine; Neuromuscular Diseases; S-Adenosylhomocysteine; S-Adenosylmethionine; Valine; Vitamin B 12 Deficiency | 1990 |
Combined modulation of S-adenosylmethionine biosynthesis and S-adenosylhomocysteine metabolism enhances inhibition of nucleic acid methylation and L1210 cell growth.
Topics: Adenosine; Animals; Cell Division; DNA, Neoplasm; Homocysteine; Leukemia L1210; Methylation; Polyamines; RNA, Neoplasm; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 1990 |
Effects of 9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl)-adenine and -3-deazaadenine on the metabolism of S-adenosylhomocysteine in mouse L929 cells.
Topics: Adenosine; Adenosine Kinase; Adenosylhomocysteinase; Animals; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Homocysteine; Hydrolases; Mice; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship | 1988 |
Protooncogene methylation and expression in regenerating liver and preneoplastic liver nodules induced in the rat by diethylnitrosamine: effect of variations of S-adenosylmethionine:S-adenosylhomocysteine ratio.
Topics: Animals; Diethylnitrosamine; Genes, ras; Homocysteine; Immunoblotting; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Methylation; Precancerous Conditions; Proto-Oncogenes; Rats; Rats, Inbred F344; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Biochemical analysis of the role of transmethylation in the methionine dependence of tumor cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biogenic Polyamines; Cell Division; Culture Media; Cystathionine beta-Synthase; Homocysteine; Humans; Methionine; Methionine Adenosyltransferase; Methylation; Phenotype; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1989 |
Hepatic content of S-adenosylmethionine, S-adenosylhomocysteine and glutathione in rats receiving treatments modulating methyl donor availability.
Topics: Animals; Biomarkers; Choline Deficiency; Cysteine; Diet; Fatty Liver; Folic Acid Deficiency; Glutathione; Homocysteine; Lipids; Liver; Male; Methionine; Methylation; Niacinamide; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
S-adenosylmethionine, S-adenosylhomocysteine and adenosine system. Age-dependent availability in rat brain.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Brain; Homocysteine; In Vitro Techniques; Kinetics; Male; Membranes; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Relationship between intracellular concentration of S-adenosylhomocysteine and inhibition of vaccinia virus replication and inhibition of murine L-929 cell growth.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Antibiotics, Antineoplastic; Cell Division; Chromatography, High Pressure Liquid; Homocysteine; Hydrolases; L Cells; Methylation; Mice; S-Adenosylhomocysteine; Time Factors; Vaccinia virus; Virus Replication | 1989 |
Contribution of S-adenosylhomocysteine to cardiac adenosine formation.
Topics: Adenine; Adenosine; Animals; Guinea Pigs; Heart; Homocysteine; In Vitro Techniques; Kinetics; Models, Theoretical; Myocardium; Perfusion; S-Adenosylhomocysteine | 1989 |
Elucidation of the mechanism by which homocysteine potentiates the anti-vaccinia virus effects of the S-adenosylhomocysteine hydrolase inhibitor 9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl)-adenine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Antiviral Agents; Drug Synergism; Homocysteine; Hydrolases; L Cells; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Vaccinia virus | 1989 |
Invertebrate phototransduction: involvement of cytoskeletal elements.
Topics: Animals; Astacoidea; Cattle; Colchicine; Cytoskeleton; Fibroblasts; Homocysteine; Horseshoe Crabs; Invertebrates; Isomerism; Membrane Potentials; Methyltransferases; Photoreceptor Cells; Retina; S-Adenosylhomocysteine; Signal Transduction; Tubercidin | 1989 |
Inhibition of phosphoinositide metabolism in human polymorphonuclear leukocytes by S-adenosylhomocysteine.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Homocysteine; Humans; In Vitro Techniques; Kinetics; Neutrophils; Phosphatidylinositols; S-Adenosylhomocysteine; Type C Phospholipases | 1988 |
S-adenosylmethionine, S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase variations during differentiation of Dictyostelium discoideum.
Topics: Adenosylhomocysteinase; Cell Differentiation; Cyclic AMP; Dictyostelium; Genetic Variation; Homocysteine; Hydrolases; S-Adenosylhomocysteine; S-Adenosylmethionine | 1988 |
The L protein of vesicular stomatitis virus modulates the response of the polyadenylic acid polymerase to S-adenosylhomocysteine.
Topics: Adenosine Monophosphate; Capsid; Homocysteine; Mutation; Nucleotidyltransferases; Polynucleotide Adenylyltransferase; RNA-Dependent RNA Polymerase; S-Adenosylhomocysteine; Species Specificity; Uridine Monophosphate; Vesicular stomatitis Indiana virus; Viral Core Proteins; Viral Nonstructural Proteins; Viral Proteins | 1988 |
Differential effects on growth, homocysteine, and related compounds of two inhibitors of S-adenosylhomocysteine catabolism, 3-deazaadenosine, and 3-deazaaristeromycin, in C3H/10T1/2 cells.
Topics: Adenosine; Aminoglycosides; Animals; Anti-Bacterial Agents; Cell Division; Cell Line; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; Homocysteine; Mice; Mice, Inbred C3H; S-Adenosylhomocysteine; Tubercidin | 1989 |
S-adenosylmethionine, S-adenosylhomocysteine and DNA methylation levels in the liver of rats fed methapyrilene and analogs.
Topics: Aminopyridines; Animals; Carcinogens; Deoxycytidine; DNA; Homocysteine; Liver; Male; Methapyrilene; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Evidence for altered methionine methyl-group utilization in the diabetic rat's brain.
Topics: Administration, Oral; Animals; Brain; Caseins; Diabetes Mellitus, Experimental; Diet; Female; Homocysteine; Male; Methionine; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Streptozocin; Time Factors | 1988 |
Adenosine-homocysteine interactions in controlling cyclic AMP in rat brain cortical slices.
Topics: Adenosine; Animals; Brain Chemistry; Cerebral Cortex; Cyclic AMP; Homocysteine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine | 1985 |
Modulation by the ratio S-adenosylmethionine/S-adenosylhomocysteine of cyclic AMP-dependent phosphorylation of the 50 kDa protein of rat liver phospholipid methyltransferase.
Topics: Animals; Cyclic AMP; Fluorides; Homocysteine; Kinetics; Liver; Methyltransferases; Molecular Weight; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylethanolamine N-Methyltransferase; Phosphorylation; Protein Kinases; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1985 |
Effects of S-adenosylhomocysteine and analogs on Epstein-Barr virus-induced transformation, expression of the Epstein-Barr virus capsid antigen, and methylation of Epstein-Barr virus DNA.
Topics: Capsid; Cell Line; Cell Transformation, Viral; DNA, Viral; Herpesvirus 4, Human; Homocysteine; Humans; Lymphocytes; Methylation; S-Adenosylhomocysteine; Structure-Activity Relationship | 1987 |
Effects of the transmethylation inhibitor S-adenosyl-homocysteine and of the methyl donor S-adenosyl-methionine on rat Leydig cell function in vitro.
Topics: Animals; Bucladesine; Cell Membrane; Chorionic Gonadotropin; Cyclic AMP; Dose-Response Relationship, Drug; Homocysteine; Leydig Cells; Luteinizing Hormone; Male; Methylation; Rats; Receptors, LH; S-Adenosylhomocysteine; S-Adenosylmethionine; Testosterone | 1987 |
Methylation deficiency causes vitamin B12-associated neuropathy in the pig.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Homocysteine; Methylation; Nervous System Diseases; Nitrous Oxide; S-Adenosylhomocysteine; S-Adenosylmethionine; Spinal Cord; Swine; Vitamin B 12 | 1988 |
Enzymatic process for the production of pharmacologically useful nucleosides.
Topics: Adenosylhomocysteinase; Alcaligenes; Enzymes, Immobilized; Homocysteine; Hydrolases; Kinetics; Nucleosides; S-Adenosylhomocysteine | 1988 |
Growth support and toxicity of homocysteine and its effects on methionine metabolism in non-transformed and chemically transformed C3H/10T1/2 cells.
Topics: Animals; Cell Division; Cell Line; Cysteine; Dose-Response Relationship, Drug; Glutathione; Homocysteine; Homocystine; Methionine; Mice; Mice, Inbred C3H; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1988 |
Effect of methotrexate on homocysteine and other sulfur compounds in tissues of rats fed a normal or a defined, choline-deficient diet.
Topics: Analysis of Variance; Animals; Choline Deficiency; Diet; Glutathione; Homocysteine; Kidney; Liver; Male; Methotrexate; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 1988 |
Formation of S-adenosylhomocysteine in the heart. I: An index of free intracellular adenosine.
Topics: Adenosine; Animals; Guinea Pigs; Homocysteine; Intracellular Fluid; Myocardium; S-Adenosylhomocysteine | 1988 |
Formation of S-adenosylhomocysteine in the heart. II: A sensitive index for regional myocardial underperfusion.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Coronary Circulation; Coronary Disease; Dogs; Endocardium; Homocysteine; Hydrogen-Ion Concentration; Hydrolases; Myocardium; Perfusion; S-Adenosylhomocysteine | 1988 |
S-adenosylhomocysteine metabolism in Streptomyces flocculus.
Topics: Chromatography, High Pressure Liquid; Homocysteine; Inosine; Magnetic Resonance Spectroscopy; S-Adenosylhomocysteine; Streptomyces | 1988 |
The transmethylation pathway as a source for adenosine in the isolated guinea-pig heart.
Topics: Adenosine; Animals; Guinea Pigs; Homocysteine; In Vitro Techniques; Methylation; Myocardium; Oxygen; Perfusion; S-Adenosylhomocysteine | 1988 |
1,2-Dimethylhydrazine-induced premalignant alterations in the S-adenosylmethionine/S-adenosylhomocysteine ratio and membrane lipid lateral diffusion of the rat distal colon.
Topics: 1,2-Dimethylhydrazine; Animals; Colonic Neoplasms; Decanoic Acids; Diffusion; Dimethylhydrazines; Homocysteine; Membrane Lipids; Methionine Adenosyltransferase; Methylhydrazines; Precancerous Conditions; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1988 |
Disposition of endogenous homocysteine by mouse fibroblast C3H/10T1/2 Cl 8 and the chemically transformed C3H/10T1/2 MCA Cl 16 cells following methotrexate exposure.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Chromatography, Ion Exchange; Culture Media; Fibroblasts; Homocysteine; Methotrexate; Methylcholanthrene; Mice; Mice, Inbred C3H; Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1986 |
4'-Thioadenosine as a novel inhibitor of S-adenosylhomocysteine hydrolase and an inducer for the differentiation of HL-60 human leukemia cells.
Topics: Adenosine; Adenosylhomocysteinase; Cell Differentiation; Cell Line; Chromatography, High Pressure Liquid; Homocysteine; Humans; Hydrolases; Leukemia, Myeloid, Acute; Purine Nucleotides; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1986 |
Determination of S-adenosylhomocysteine in tissues following pharmacological inhibition of S-adenosylhomocysteine catabolism.
Topics: Adenosylhomocysteinase; Animals; Coformycin; Freezing; Homocysteine; Hydrolases; Mice; Pentostatin; Ribonucleosides; S-Adenosylhomocysteine; Time Factors; Tissue Distribution; Vidarabine | 1986 |
Effect of S-adenosylhomocysteine on insulin-independent release of pyruvate dehydrogenase activator from rat adipocyte plasma membranes.
Topics: Adipose Tissue; Animals; Cell Membrane; Homocysteine; In Vitro Techniques; Insulin; Male; Methylation; Phospholipids; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine | 1987 |
Methionine metabolism in isolated perfused livers from rats fed on zinc-deficient and restricted diets.
Topics: Animals; Butyrates; Cystathionine; Diet; Homocysteine; In Vitro Techniques; Liver; Male; Methionine; Perfusion; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Zinc | 1986 |
Compartmentalization of S-adenosylhomocysteine in rat liver. Determination and characterization of the in vivo protein binding.
Topics: Animals; Cytosol; Homocysteine; Liver; Microsomes, Liver; Protein Binding; Rats; S-Adenosylhomocysteine | 1987 |
Resistance to multiple adenine nucleoside and methionine analogues in mutant murine lymphoma cells with enlarged S-adenosylmethionine pools.
Topics: Adenosine; Animals; Cells, Cultured; Drug Resistance; Homocysteine; Kinetics; Lymphoma; Methionine; Methionine Adenosyltransferase; Mice; Mutation; S-Adenosylhomocysteine; S-Adenosylmethionine | 1986 |
In vivo depletion of S-adenosyl-L-homocysteine and S-adenosyl-L-methionine in guinea pig lung after chronic S-(-)-nicotine administration.
Topics: Animals; Chromatography, High Pressure Liquid; Guinea Pigs; Homocysteine; Injections, Subcutaneous; Liver; Lung; Male; Nicotine; S-Adenosylhomocysteine; S-Adenosylmethionine; Stereoisomerism | 1986 |
Possible involvement of the S-adenosyl-L-homocysteine metabolites, adenosine and L-homocysteine, in sleep in rats.
Topics: Adenosine; Animals; Electroencephalography; Homocysteine; Male; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; Sleep Stages; Sleep, REM; Time Factors | 1986 |
Disposition of homocysteine and S-3-deazaadenosylhomocysteine in cells exposed to 3-deazaadenosine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Fibroblasts; Homocysteine; Hydrolases; Liver; Mice; Neoplasms, Experimental; Protein Binding; Rats; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1986 |
Disposition of homocysteine in rat hepatocytes and in nontransformed and malignant mouse embryo fibroblasts following exposure to inhibitors of S-adenosylhomocysteine catabolism.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Adenosylhomocysteinase; Animals; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Homocysteine; Hydrolases; In Vitro Techniques; Liver; Methionine; Rats; S-Adenosylhomocysteine | 1986 |
The chemical synthesis of high specific-activity [35S]adenosylhomocysteine.
Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Homocysteine; S-Adenosylhomocysteine; Sulfur Radioisotopes | 1986 |
Synthesis of some S-3'-deoxyadenosyl-L-homocysteine analogues.
Topics: Chromatography, Thin Layer; Homocysteine; Indicators and Reagents; Magnetic Resonance Spectroscopy; S-Adenosylhomocysteine; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1987 |
Abnormalities in S-adenosylhomocysteine hydrolysis, ATP catabolism, and lymphoid differentiation in adenosine deaminase deficiency.
Topics: Adenosine Deaminase; Adenosine Triphosphate; Adenosylhomocysteinase; Anemia, Hemolytic, Congenital; Cell Differentiation; Child; Chromosome Mapping; Erythrocytes; Hematopoietic Stem Cells; Homocysteine; Humans; Hydrolases; Hydrolysis; Lymphocytes; Nucleoside Deaminases; S-Adenosylhomocysteine | 1985 |
An analysis of multiple mechanisms of adenosine toxicity in baby hamster kidney cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cell Adhesion; Cell Line; Coformycin; Drug Resistance; Drug Synergism; Guinea Pigs; Homocysteine; Kidney; Nucleotides; Pentostatin; Ribonucleotide Reductases; S-Adenosylhomocysteine; Uridine | 1985 |
Differential regulation of polyamine synthesis and transmethylation reactions in methylthioadenosine phosphorylase deficient mammalian cells.
Topics: Adenosine; Animals; B-Lymphocytes; Cell Division; Cell Line; Deoxyadenosines; Fibroblasts; Homocysteine; Humans; Kinetics; Methylation; Mice; Pentosyltransferases; Polyamines; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; T-Lymphocytes; Thionucleosides | 1985 |
Radioenzymic determination of homocysteine in plasma and urine.
Topics: Adult; Blood Proteins; Chromatography, Gel; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Male; Middle Aged; Protein Binding; S-Adenosylhomocysteine; Specimen Handling | 1985 |
Effect of S-adenosylhomocysteine on sulfhydryl xenobiotic transmethylases in rat liver.
Topics: Animals; Homocysteine; Liver; Male; Methyltransferases; Microsomes, Liver; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1985 |
Phospholipid methylase activity, [3H]S-adenosyl-L-homocysteine binding, and S-adenosyl-L-methionine and S-adenosyl-L-homocysteine levels in rat brain during maturation.
Topics: Animals; Animals, Newborn; Brain; Cell Membrane; Cerebral Cortex; Homocysteine; Male; Methyltransferases; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylethanolamine N-Methyltransferase; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1985 |
Inhibition of protein carboxylmethylation and dopamine autoreceptor functioning.
Topics: Animals; Apomorphine; Corpus Striatum; Dopamine; Homocysteine; Male; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; Sulpiride; Synaptosomes | 1985 |
A radioisotope assay for 1-aminocyclopropane-1-carboxylic acid synthase: S-adenosylhomocysteine analogs as inhibitors of the enzyme involved in plant senescence.
Topics: Amino Acids; Amino Acids, Cyclic; Chromatography, High Pressure Liquid; Homocysteine; Lyases; Nucleosides; Plants; S-Adenosylhomocysteine | 1985 |
The role of S-adenosylhomocysteine in the biological utilization of S-adenosylmethionine.
Topics: Alcaligenes; Animals; Dictyostelium; Homocysteine; Humans; Kinetics; Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine | 1985 |
The effect of diazepam on brain levels of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine: possible correlation with protection from methionine sulfoximine seizures.
Topics: Animals; Brain Chemistry; Diazepam; Dose-Response Relationship, Drug; Homocysteine; Male; Methionine Sulfoximine; Methylation; Mice; Reaction Time; S-Adenosylhomocysteine; S-Adenosylmethionine; Seizures | 1985 |
Activation and inactivation of striatal tyrosine hydroxylase: the effects of pH, ATP and cyclic AMP, S-adenosylmethionine and S-adenosylhomocysteine.
Topics: Adenosine Triphosphate; Animals; Corpus Striatum; Cyclic AMP; Enzyme Activation; Haloperidol; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tyrosine 3-Monooxygenase | 1983 |
Inhibition of bacterial DNA cytosine-5-methyltransferase by S-adenosyl-L-homocysteine and some related compounds.
Topics: DNA (Cytosine-5-)-Methyltransferases; Escherichia coli; Homocysteine; Kinetics; Methyltransferases; Mutation; S-Adenosylhomocysteine | 1984 |
Tropolone antagonism of the L-dopa-induced elevation of S-adenosylhomocysteine: S-adenosylmethionine ratio but not depletion of adrenaline in rat hypothalamus.
Topics: Animals; Catechol O-Methyltransferase Inhibitors; Epinephrine; Homocysteine; Hypothalamus; Levodopa; Male; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tropolone | 1984 |
Evidence that the inhibitory effect of adenosine, but not cordycepin, on the methylation of nuclear RNA is mediated by S-adenosylhomocysteine hydrolase.
Topics: Adenosine; Adenosylhomocysteinase; Adult; Animals; Cell Nucleus; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Leukemia L1210; Methylation; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Inhibition of IgE-mediated histamine release from rat basophilic leukemia cells and rat mast cells by inhibitors of transmethylation.
Topics: Adenine; Adenosine; Animals; Basophils; Female; Histamine Release; Homocysteine; Immunoglobulin E; Leukemia; Mast Cells; Methylation; Mice; Rabbits; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1981 |
Effect of inhibitors of methylation on early and late interferon synthesis in bovine kidney cell cultures.
Topics: Adenine; Adenosine; Animals; Cattle; Cells, Cultured; Cycloheximide; Cycloleucine; Homocysteine; Interferons; Methylation; Newcastle disease virus; Poly I-C; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Increase in S-adenosylhomocysteine concentration in interferon-treated HeLa cells and inhibition of methylation of vesicular stomatitis virus mRNA.
Topics: Chromatography, High Pressure Liquid; HeLa Cells; Homocysteine; Humans; Interferons; Methylation; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Vesicular stomatitis Indiana virus | 1983 |
A comparison of the effects of S-adenosyl-L-homocysteine on sleep in normal and pinealectomized rats.
Topics: Animals; Homocysteine; Male; Pineal Gland; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; Sleep | 1983 |
Fragile X expression is decreased by 5-azacytidine and S-adenosylhomocysteine.
Topics: Azacitidine; Cell Line; Culture Media; DNA; Dose-Response Relationship, Drug; Floxuridine; Fragile X Syndrome; Homocysteine; Humans; Karyotyping; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Chromosome Aberrations | 1983 |
Modulation by S-adenosyl-methionine and S-adenosyl-homocysteine of the human leucocytes histamine release.
Topics: Allergens; Cromolyn Sodium; Histamine Release; Homocysteine; Humans; Leukocytes; S-Adenosylhomocysteine; S-Adenosylmethionine; Theophylline | 1984 |
Effect of undermethylation on mRNA cytoplasmic appearance and half-life.
Topics: Chromatography, High Pressure Liquid; Half-Life; HeLa Cells; Homocysteine; Humans; Kinetics; Methylation; Poly A; RNA; RNA, Messenger; RNA, Neoplasm; S-Adenosylhomocysteine | 1984 |
Effect of S-adenosyl-L-homocysteine upon sleep in p-chlorophenylalanine pretreated rats.
Topics: Animals; Circadian Rhythm; Drug Interactions; Fenclonine; Homocysteine; Male; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; Sleep | 1984 |
[Solubilization of cerebral binding sites of S-adenosyl-L-homocysteine].
Topics: Animals; Binding Sites; Brain; Cell Membrane; Detergents; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methyltransferases; Molecular Weight; Octoxynol; Phosphatidylethanolamine N-Methyltransferase; Polyethylene Glycols; Rats; S-Adenosylhomocysteine; Solubility | 1984 |
Resistance of an adenosine kinase-deficient human lymphoblastoid cell line to effects of deoxyadenosine on growth, S-adenosylhomocysteine hydrolase inactivation, and dATP accumulation.
Topics: Adenosine Kinase; Adenosylhomocysteinase; Cell Division; Cell Line; Deoxyadenine Nucleotides; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Immunologic Deficiency Syndromes; Lymphocytes; Phosphotransferases; S-Adenosylhomocysteine; Spleen | 1980 |
In vitro and in vivo binding of S-adenosyl-L-homocysteine to membranes from rat cerebral cortex.
Topics: Adenosine; Animals; Brain Chemistry; Calcium; Cell Membrane; Cerebral Cortex; Chromatography, High Pressure Liquid; Homocysteine; Magnesium; Male; Protein Binding; Rats; Receptors, Neurotransmitter; S-Adenosylhomocysteine; Time Factors | 1981 |
Lack of correlation between plasminogen activator production and the continous expression of the transformed phenotype of chicken and mammalian cells as shown with S-adenosyl homocysteine analogues.
Topics: Animals; Avian Sarcoma Viruses; Cattle; Cell Line; Cell Transformation, Viral; Chick Embryo; Cricetinae; Fibroblasts; Homocysteine; Humans; Mutation; Phenotype; Plasminogen Activators; S-Adenosylhomocysteine; Temperature | 1981 |
Microsomal phosphatidylethanolamine methyltransferase: effect of altered S-adenosylmethionine-S-adenosylhomocysteine ratios in rat liver.
Topics: Animals; Bromobenzenes; Diacylglycerol Cholinephosphotransferase; Female; Homocysteine; Liver; Methyltransferases; Microsomes, Liver; Phosphatidylethanolamine N-Methyltransferase; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Starvation | 1981 |
Comparative effect of S-adenosyl-homocysteine (SAH) and Sinefungin on tRNA-base methylation in whole cells and in vitro.
Topics: Adenine; Adenosine; Animals; Antifungal Agents; Avian Sarcoma Viruses; Cell Transformation, Viral; Escherichia coli; Guanine; Homocysteine; Methylation; RNA, Transfer; S-Adenosylhomocysteine | 1981 |
Determination of adenosylhomocysteine in urine of immunodeficient children.
Topics: Anions; Bicarbonates; Borates; Child; Child, Preschool; Chromatography, Ion Exchange; Female; Homocysteine; Humans; Hydrogen-Ion Concentration; Immunologic Deficiency Syndromes; Infant; Infant, Newborn; Male; S-Adenosylhomocysteine; Sodium Bicarbonate; Spectrometry, Fluorescence | 1981 |
Evidence against a requirement for phospholipid methylation in adenylate cyclase activation by hormones. Methyltransferase inhibitors do not impair cyclic AMP accumulation induced by glucagon or beta-adrenergic agents in rat hepatocytes.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Epinephrine; Glucagon; Homocysteine; Isomerism; Isoproterenol; Liver; Methyltransferases; Phospholipids; Rats; S-Adenosylhomocysteine; Tubercidin | 1982 |
Potentiation of the growth inhibitory effects of adenosine 3',5'-monophosphate analogues by homocysteine.
Topics: Animals; Bucladesine; Carcinoma 256, Walker; Drug Synergism; Homocysteine; Methylation; S-Adenosylhomocysteine | 1982 |
Effects of S-adenosylhomocysteine analogues on vaccinia viral messenger ribonucleic acid synthesis and methylation.
Topics: Adenosine; Chemical Phenomena; Chemistry; DNA-Directed RNA Polymerases; Homocysteine; Kinetics; Methyltransferases; Nucleotidyltransferases; RNA, Viral; S-Adenosylhomocysteine; Structure-Activity Relationship; Vaccinia virus | 1982 |
[Effect of S-adenosine homocysteine and dibutyril-3',5-AMP on lysosomal membranes of eye tissue in ocular herpes].
Topics: Animals; Bucladesine; Eye; Glycoside Hydrolases; Homocysteine; Keratitis, Dendritic; Lysosomes; Male; Malondialdehyde; Rabbits; S-Adenosylhomocysteine | 1982 |
Reduced availability of endogenously synthesized methionine for S-adenosylmethionine formation in methionine-dependent cancer cells.
Topics: Cell Division; Cell Line; Cell Transformation, Viral; Homocysteine; Humans; Methionine; Neoplasms, Experimental; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1982 |
The effects of S-adenosylhomocysteine and S-adenosylmethionine on some purine- and pyrimidine-metabolizing systems.
Topics: 5'-Nucleotidase; Adenosine Deaminase Inhibitors; Adenylate Kinase; AMP Deaminase; Homocysteine; Nucleoside-Phosphate Kinase; Nucleotidases; Purine-Nucleoside Phosphorylase; Purines; Pyrimidines; S-Adenosylhomocysteine; S-Adenosylmethionine | 1982 |
The effects of S-adenosyl methionine (AdoMet) and its analogues on the control of transcription and translation in vitro of the mRNA products of two cytoplasmic polyhedrosis viruses.
Topics: Adenosine; Cell-Free System; DNA-Directed RNA Polymerases; Ethionine; Homocysteine; Insect Viruses; Kinetics; Plants; Protein Biosynthesis; Ribonucleotides; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity; Transcription, Genetic; Triticum | 1983 |
[S-adenosyl-L-homocysteine: 1. Influence on sleep].
Topics: Animals; Cats; Drug Synergism; Female; Fenclonine; Homocysteine; Iproniazid; Male; Norepinephrine; Rabbits; Rats; Reserpine; S-Adenosylhomocysteine; Serotonin; Sleep; Sleep, REM; Time Factors | 1980 |
The effect of aliphatic adenine analogues on S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase in intact rat hepatocytes.
Topics: Adenine; Adenosylhomocysteinase; Animals; Enzyme Activation; Homocysteine; Hydrolases; In Vitro Techniques; Kinetics; Liver; Mice; S-Adenosylhomocysteine; Structure-Activity Relationship | 1984 |
Elevated overall rates of transmethylation in cell lines from diverse human tumors.
Topics: Adenosylhomocysteinase; Cell Line; Homocysteine; Humans; Hydrolases; Methionine; Methylation; Neoplasms, Experimental; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1984 |
Brain methylation and epileptogenesis: the case of methionine sulfoximine.
Topics: Adenosine; Animals; Brain; Epilepsy; Histamine; Homocysteine; Methionine; Methionine Sulfoximine; Methylation; Methylhistamines; Mice; Nerve Tissue Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Correlations between phospholipid methylation and neuronal catecholamine transport.
Topics: Adenine; Adenosine; Animals; Biological Transport; Cerebral Cortex; Cytosol; Homocysteine; Kinetics; Male; Membrane Lipids; Methylation; Norepinephrine; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; Synaptosomes | 1984 |
Inhibition of protein carboxyl methylation by S-adenosyl-L-homocysteine in intact erythrocytes. Physiological consequences.
Topics: Adenosine; Aspartic Acid; Erythrocyte Membrane; Erythrocytes; Homocysteine; Humans; Membrane Proteins; Methionine; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Selection and characterization of a murine lymphoid cell line partially deficient in S-adenosylhomocysteine hydrolase.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cell Line; Cell Separation; Clone Cells; Homocysteine; Hydrolases; Lymphoma; Mice; S-Adenosylhomocysteine; T-Lymphocytes | 1983 |
S-adenosylhomocysteine catabolism and basis for acquired resistance during treatment of T-cell acute lymphoblastic leukemia with 2'-deoxycoformycin alone and in combination with 9-beta-D-arabinofuranosyladenine.
Topics: Acute Disease; Adenosine; Adult; Coformycin; Deoxyadenosines; Drug Resistance; Drug Therapy, Combination; Erythrocytes; Homocysteine; Humans; Leukemia, Lymphoid; Lymphocytes; Male; Pentostatin; Ribonucleosides; S-Adenosylhomocysteine; Time Factors; Vidarabine | 1983 |
Effect of 2'-deoxycoformycin infusion on S-adenosylhomocysteine hydrolase and the amount of S-adenosylhomocysteine and related compounds in tissues of mice.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosylhomocysteinase; Animals; Coformycin; Deoxyadenosines; Homocysteine; Hydrolases; Infusions, Parenteral; Jejunum; Kidney; Kinetics; Liver; Mice; Nucleoside Deaminases; Organ Specificity; Pentostatin; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine | 1983 |
Effect of methotrexate with 5-methyltetrahydrofolate rescue and dietary homocystine on survival of leukemic mice and on concentrations of liver adenosylamino acids.
Topics: Animals; Diet; Homocysteine; Homocystine; Kinetics; Leukemia L1210; Leukemia L5178; Leukemia, Experimental; Liver; Male; Methotrexate; Mice; Mice, Inbred DBA; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 1983 |
A radioisotopic method for the determination of S-adenosyl-L-homocysteine in tissues in the 10(-7) M range.
Topics: Animals; Brain Chemistry; Homocysteine; Mathematics; Microchemistry; Rats; S-Adenosylhomocysteine | 1983 |
Isolation of S-adenosyl-3-thiopropylamine.
Topics: Animals; Chromatography, Ion Exchange; Eye; Fishes; Homocysteine; S-Adenosylhomocysteine | 1983 |
Methylation of phospholipids in microsomes of the rat aorta.
Topics: Animals; Aorta, Thoracic; Chromatography, Thin Layer; Fluorescence Polarization; Homocysteine; Male; Methylation; Microsomes; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Trypsin; Type C Phospholipases | 1983 |
Binding of S-adenosylhomocysteine to various domains of the plasma membrane and to the endoplasmic reticulum from rat liver: relation between binding and phospholipid methyltransferase activity.
Topics: Animals; Binding Sites; Cell Membrane; Endoplasmic Reticulum; Homocysteine; In Vitro Techniques; Liver; Male; Methyltransferases; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylethanolamine N-Methyltransferase; Protein Binding; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine | 1983 |
Homocysteine in tissues of the mouse and rat.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Homocysteine; Mice; Rats; S-Adenosylhomocysteine; Species Specificity; Tissue Distribution | 1984 |
Altered methionine metabolism occurs in all members of a set of diverse human tumor cell lines.
Topics: Cell Line; Homocysteine; Humans; Methionine; Models, Biological; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Autoradiographic localization of [14C]8-S-adenosyl-L-homocysteine in rat brain.
Topics: Animals; Autoradiography; Blood-Brain Barrier; Brain; Cerebral Ventricles; Choroid Plexus; Chromatography, High Pressure Liquid; Homocysteine; Male; Pineal Gland; Rats; S-Adenosylhomocysteine | 1984 |
Biochemical and immunological evaluation of long term coformycin administration in the mouse.
Topics: Adenosine Deaminase; Animals; Cells, Cultured; Coformycin; DNA Replication; Homocysteine; Lymphocyte Activation; Lymphocytes; Mice; Nucleoside Deaminases; Ribonucleosides; S-Adenosylhomocysteine; Tissue Distribution | 1984 |
S-adenosylhomocysteine hydrolase as a pharmacological target for the inhibition of transmethylation.
Topics: Adenosine; Animals; Enzyme Inhibitors; Homocysteine; Isomerism; Kinetics; Mice; Ribonucleosides; S-Adenosylhomocysteine; Structure-Activity Relationship; Tubercidin | 1984 |
Binding of S-adenosylhomocysteine to hydroxyindole O-methyltransferase.
Topics: Acetylserotonin O-Methyltransferase; Animals; Binding Sites; Cattle; Homocysteine; Kinetics; Methyltransferases; Pineal Gland; Protein Binding; S-Adenosylhomocysteine | 1984 |
Methionine metabolism in mammals. Distribution of homocysteine between competing pathways.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosine Deaminase; Adenosylhomocysteinase; Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Homocysteine; Hydrolases; In Vitro Techniques; Liver; Male; Methionine; Methyltransferases; Models, Biological; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
[Affinity of tritiated S-adenosyl-L-homocysteine for membrane preparations from various parts of rat the rat brain].
Topics: Animals; Binding Sites; Brain; Cell Membrane; Homocysteine; In Vitro Techniques; Kinetics; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Rats; S-Adenosylhomocysteine; Tritium | 1981 |
Adenosine metabolism: modification by S-adenosylhomocysteine and 5'-methylthioadenosine.
Topics: Adenosine; Adenosine Kinase; Adenosylhomocysteinase; B-Lymphocytes; Cells, Cultured; Deoxyadenosines; Erythrocytes; Homocysteine; Humans; Hydrolases; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; T-Lymphocytes; Thionucleosides | 1982 |
Biosynthesis of polyamines in mouse brain: effects of methionine sulfoximine and adenosylhomocysteine.
Topics: Animals; Brain; Homocysteine; Male; Methionine Sulfoximine; Methylation; Mice; Polyamines; Putrescine; S-Adenosylhomocysteine; Spermidine; Spermine | 1983 |
S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase in various tissues of mice given injections of 9-beta-D-arabinofuranosyladenine.
Topics: Adenosylhomocysteinase; Animals; Homocysteine; Hydrolases; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; S-Adenosylhomocysteine; Tissue Distribution; Vidarabine | 1983 |
In vivo elevation of mouse brain S-adenosyl-L-homocysteine after treatment with L-homocysteine.
Topics: Adenosine; Animals; Brain; Homocysteine; Kinetics; Male; Mice; S-Adenosylhomocysteine | 1983 |
Adenosine metabolism in a rat hippocampal slice preparation: incorporation into S-adenosylhomocysteine.
Topics: Adenosine; Animals; Carbon Radioisotopes; Hippocampus; Homocysteine; In Vitro Techniques; Kinetics; Male; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine | 1983 |
Tissue levels of S-adenosylmethionine and S-adenosylhomocysteine in rats fed methyl-deficient, amino acid-defined diets for one to five weeks.
Topics: Animals; Body Weight; Choline Deficiency; Diet; Folic Acid Deficiency; Homocysteine; Kinetics; Liver; Lung; Male; Methionine; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Testis; Tissue Distribution; Vitamin B 12 Deficiency | 1983 |
A sensitive radiochemical enzyme assay for S-adenosyl-L-homocysteine and L-homocysteine.
Topics: Adenosine; Adenosine Deaminase; Adenosylhomocysteinase; Animals; Aspergillus oryzae; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Homocysteine; Humans; Hydrolases; Leukemia, Lymphoid; Liver; Lymphocytes; Methods; Mice; S-Adenosylhomocysteine; Tritium | 1981 |
Transcription initiation by RNA polymerase II is inhibited by S-adenosylhomocysteine.
Topics: Adenoviruses, Human; Base Composition; DNA-Directed RNA Polymerases; DNA, Recombinant; HeLa Cells; Homocysteine; Humans; Protein Biosynthesis; RNA Polymerase II; RNA, Messenger; S-Adenosylhomocysteine; Transcription, Genetic | 1982 |
Perturbations in S-adenosylhomocysteine and S-adenosylmethionine metabolism: effects on transmethylation.
Topics: Adenosine; Adenosylhomocysteinase; Cell Line; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Lymphocytes; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 1980 |
S-Adenosylhomocysteine accumulation and selective cytotoxicity in cultured T- and B-lymphocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosylhomocysteinase; B-Lymphocytes; Cell Division; Cells, Cultured; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Nucleoside Deaminases; S-Adenosylhomocysteine; T-Lymphocytes | 1982 |
S-adenosylhomocysteine is bound to pineal hydroxyindole O-methyl transferase.
Topics: Acetylserotonin O-Methyltransferase; Animals; Cattle; Chromatography, Affinity; Chromatography, Thin Layer; Homocysteine; Immunosorbent Techniques; Methyltransferases; Pineal Gland; Rabbits; S-Adenosylhomocysteine; Spectrophotometry, Ultraviolet | 1980 |
Inhibition of chemotaxis by S-3-deazaadenosylhomocysteine in a mouse macrophage cell line.
Topics: Animals; Cell Line; Chemotaxis; Homocysteine; Isomerism; Kinetics; Macrophages; Mice; S-Adenosylhomocysteine; Structure-Activity Relationship; Tubercidin | 1982 |
The regional concentrations of S-adenosyl-L-methionine, S-adenosyl-L-homocysteine, and adenosine in rat brain.
Topics: Adenosine; Aging; Animals; Brain; Brain Chemistry; Homocysteine; Male; Pineal Gland; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tissue Distribution | 1982 |
Inactivation of S-adenosylhomocysteine hydrolase by 9-beta-D-arabinofuranosyladenine in intact cells.
Topics: Adenosylhomocysteinase; Animals; Biological Transport; Cells, Cultured; Chromatography, High Pressure Liquid; Enzyme Activation; Homocysteine; Humans; Hydrolases; Kinetics; Leukemia, Experimental; Liver; Mice; Plasmacytoma; S-Adenosylhomocysteine; S-Adenosylmethionine; Vidarabine | 1982 |
Methionine metabolism in mammals: concentration of metabolites in rat tissues.
Topics: Amino Acids, Sulfur; Animals; Cysteine; Cystine; Dietary Proteins; Homeostasis; Homocysteine; Male; Methionine; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfhydryl Compounds; Tissue Distribution | 1982 |
Increase of paradoxical sleep induced by S-adenosyl-L-homocysteine.
Topics: Acetylserotonin O-Methyltransferase; Animals; Dose-Response Relationship, Drug; Homocysteine; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; Sleep, REM; Stimulation, Chemical; Time Factors | 1982 |
Purification of spermidine synthase from rat ventral prostate by affinity chromatography on immobilized S-adenosyl(5')-3-thiopropylamine.
Topics: Animals; Chromatography, Affinity; Chromatography, Gel; Homocysteine; Kinetics; Male; Molecular Weight; Prostate; Rats; S-Adenosylhomocysteine; Spermidine Synthase; Transferases | 1982 |
SAH analogs, modified in the aminoacid region, inhibitors of phosphatidyl-ethanolamine methylase activity and 3H-SAH binding to rat brain membranes.
Topics: Animals; Brain; Homocysteine; In Vitro Techniques; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Rats; S-Adenosylhomocysteine; Structure-Activity Relationship; Tritium | 1982 |
Characterization of S-adenosylhomocysteine binding to isolated rat hepatocytes and purified rat liver plasma membranes. Effect of analogues of S-adenosylhomocysteine.
Topics: Animals; Cell Membrane; Cells, Cultured; Homocysteine; In Vitro Techniques; Kinetics; Liver; Protein Binding; Rats; S-Adenosylhomocysteine | 1982 |
Inhibition of calf thymus and rat hypothalamic synaptosomal protein carboxymethyltransferase by analogues of S-adenosylhomocysteine.
Topics: Animals; Cattle; Homocysteine; Hypothalamus; In Vitro Techniques; Male; Protein Methyltransferases; Protein O-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; Synaptosomes; Thymus Gland | 1982 |
The mechanism of inhibition of valyl-tRNA synthetase by S-adenosylhomocysteine.
Topics: Amino Acyl-tRNA Synthetases; Homocysteine; Kinetics; S-Adenosylhomocysteine; Seeds; Structure-Activity Relationship; Valine-tRNA Ligase | 1982 |
Effect of 9-beta-D-arabinofuranosyladenine and erythro-9-(2-hydroxy-3-nonyl) adenine on the metabolism of S-adenosylhomocysteine, S-adenosylmethionine, and adenosine in rat liver.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Female; Homocysteine; Hydrolases; Liver; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Vidarabine | 1982 |
Inhibition of phospholipid methylation in isolated rat hepatocytes by analogues of adenosine and S-adenosylhomocysteine.
Topics: Adenosine; Animals; Homocysteine; In Vitro Techniques; Liver; Methylation; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Rats; S-Adenosylhomocysteine | 1982 |
S-adenosyl-L-homocysteine: simplified enzymatical preparation with high yield.
Topics: Adenosylhomocysteinase; Animals; Cattle; Chemical Phenomena; Chemistry; Homocysteine; Hydrolases; Liver; S-Adenosylhomocysteine | 1982 |
Decreased in vivo protein and phospholipid methylation after in vivo elevation of brain S-adenosyl-homocysteine.
Topics: Adenosine; Animals; Brain; Homocysteine; Male; Methylation; Mice; Nerve Tissue Proteins; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Decreased transmethylation of biogenic amines after in vivo elevation of brain S-adenosyl-l-homocysteine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Biogenic Amines; Brain; Catechol O-Methyltransferase Inhibitors; Histamine; Histamine N-Methyltransferase; Homocysteine; Hydrolases; Liver; Male; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Interaction of S-adenosylhomocysteine with isolated rat hepatocytes.
Topics: Adenosine; Animals; Binding Sites; Binding, Competitive; Biological Transport, Active; Cell Membrane; Homocysteine; Hydrolysis; In Vitro Techniques; Kinetics; Liver; Rats; S-Adenosylhomocysteine | 1981 |
Stimulation of transcription by S-adenosyl-L-homocysteine and virion-encapsidated methyl donor in spring viraemia of carp virus.
Topics: Animals; Capsid; Carps; Homocysteine; Kinetics; Methylation; Rhabdoviridae; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcription, Genetic; Virion | 1981 |
Microsomal phosphatidylethanolamine methyltransferase: inhibition by S-adenosylhomocysteine.
Topics: Animals; Female; Guinea Pigs; Homocysteine; Kinetics; Methyltransferases; Mice; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rabbits; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Phosphatidylethanolamine methylation in membranes from rat cerebral cortex : effect of exogenous phospholipids and S-adenosylhomocysteine.
Topics: Animals; Cerebral Cortex; Homocysteine; In Vitro Techniques; Membranes; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phospholipids; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Role of S-adenosylhomocysteine hydrolase in adenosine metabolism in mammalian heart.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cats; Dogs; Guinea Pigs; Heart; Homocysteine; Hydrolases; Hypoxia; In Vitro Techniques; Kinetics; Myocardium; Rabbits; Rats; S-Adenosylhomocysteine; Species Specificity | 1981 |
Synthesis of S-(3-deazaadenosyl)-L-homocysteine.
Topics: Chemical Phenomena; Chemistry; Homocysteine; Magnetic Resonance Spectroscopy; S-Adenosylhomocysteine | 1981 |
Inhibition of phospholipid methyltransferase(s) from rat liver plasma membranes by analogues of S-adenosylhomocysteine.
Topics: Animals; Cell Membrane; Chemical Phenomena; Chemistry; Homocysteine; In Vitro Techniques; Kinetics; Liver; Methyltransferases; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Rats; S-Adenosylhomocysteine; Time Factors | 1981 |
[A new method for determination of adenosylmethionine, adenosyl-homocysteine and decarboxylated adenosylmethionine].
Topics: Animals; Chromatography, High Pressure Liquid; Homocysteine; Liver; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Inhibition by S-adenosyl-L-homocysteine of dopamine dependent adenylate cyclase in rat retina.
Topics: Adenylyl Cyclase Inhibitors; Animals; Dopamine; Homocysteine; Male; Rats; Retina; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Effect of S-adenosylhomocystein on color avoidance behavior.
Topics: Animals; Avoidance Learning; Color; Goldfish; Homocysteine; Lighting; S-Adenosylhomocysteine | 1980 |
[S-adenosyl-L-homocysteine: 2. An anticonvulsant].
Topics: Amino Acids; Animals; Anticonvulsants; Brain; Convulsants; Electric Stimulation; gamma-Aminobutyric Acid; Hippocampus; Homocysteine; In Vitro Techniques; Male; Mice; Rats; S-Adenosylhomocysteine | 1980 |
S-Adenosylhomocysteine metabolism in adenosine deaminase deficient cells.
Topics: Adenosine; Adenosine Deaminase; Adenosylhomocysteinase; Cell Survival; Cells, Cultured; Homocysteine; Humans; Hydrolases; Lymphocytes; Nucleoside Deaminases; S-Adenosylhomocysteine | 1980 |
S-Adenosylmethionine and S-adenosylhomocystein metabolism in isolated rat liver. Effects of L-methionine, L-homocystein, and adenosine.
Topics: Adenosine; Animals; DNA; Female; Histones; Homocysteine; Kinetics; Liver; Methionine; Perfusion; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
The rate of transmethylation in mouse liver as measured by trapping S-adenosylhomocysteine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Homocysteine; Hydrolases; Liver; Methylation; Mice; S-Adenosylhomocysteine | 1980 |
Determination of S-adenosylmethionine and S-adenosylhomocysteine in nuclei isolated from sea urchin embryos during early development.
Topics: Animals; Cell Nucleus; Embryo, Nonmammalian; Homocysteine; S-Adenosylhomocysteine; S-Adenosylmethionine; Sea Urchins | 1980 |
Carbon tetrachloride-induced hepatic injury is associated with global DNA hypomethylation and homocysteinemia: effect of S-adenosylmethionine treatment.
Topics: Animals; Carbon Tetrachloride; Cystathionine; DNA; Folic Acid; Homocysteine; Liver; Liver Cirrhosis, Experimental; Male; Methionine; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1995 |
Homocysteine enhances the inhibitory effect of extracellular adenosine on the synthesis of proteins in isolated rat hepatocytes.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cell Survival; Cells, Cultured; Drug Synergism; Homocysteine; Hydrolases; Inosine; Kinetics; Liver; Male; Protein Biosynthesis; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 1995 |
Prevention of neural tube defects by and toxicity of L-homocysteine in cultured postimplantation rat embryos.
Topics: Adenosylhomocysteinase; Animals; Catalase; Copper; Copper Sulfate; Culture Techniques; Drug Interactions; Embryonic and Fetal Development; Embryonic Development; Female; Homocysteine; Homocystine; Hydrolases; Methionine; Neural Tube Defects; Oxidation-Reduction; Pregnancy; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Stereoisomerism; Teratogens; Vitamin B 12 | 1994 |
Mechanism of erythrocyte accumulation of methylation inhibitor S-adenosylhomocysteine in uremia.
Topics: Adenosine; Adenosylhomocysteinase; Adult; Aspartate Aminotransferases; Erythrocytes; Female; Homocysteine; Humans; Hydrolases; Male; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Uremia | 1995 |
The methyltransferase inhibitor Neplanocin A interferes with influenza virus replication by a mechanism different from that of 3-deazaadenosine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Chick Embryo; Drug Synergism; Homocysteine; Hydrolases; Influenza A virus; Methionine; Methyltransferases; RNA Caps; RNA, Viral; S-Adenosylhomocysteine; Tubercidin; Viral Proteins; Virus Replication | 1995 |
Effects of ageing on folate metabolism in rats fed a long-term folate deficient diet.
Topics: Aging; Animals; Folic Acid; Folic Acid Deficiency; Homocysteine; Liver; Male; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1994 |
Adenosine and homocysteine together enhance TNF-mediated cytotoxicity but do not alter activation of nuclear factor-kappa B in L929 cells.
Topics: Adenosine; Cell Line; Cell Survival; Drug Synergism; Homocysteine; In Vitro Techniques; Methylation; NF-kappa B; Reactive Oxygen Species; S-Adenosylhomocysteine; Tumor Necrosis Factor-alpha | 1994 |
Steady-state catecholamine stimulation does not increase cytosolic adenosine in canine hearts.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Pressure; Cardiac Pacing, Artificial; Catecholamines; Coronary Circulation; Cytosol; Dogs; Heart; Heart Rate; Hemodynamics; Homocysteine; Homocystine; Myocardial Ischemia; Myocardium; Oxygen Consumption; Reference Values; S-Adenosylhomocysteine | 1994 |
Intracellular formation and release of adenosine from rat hippocampal slices evoked by electrical stimulation or energy depletion.
Topics: Adenosine; Adenosine Diphosphate; Animals; Electric Stimulation; Energy Metabolism; Hippocampus; Homocysteine; In Vitro Techniques; Intracellular Membranes; Male; Purines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine | 1993 |
Attenuation of ischemia-induced extracellular adenosine accumulation by homocysteine.
Topics: Adenosine; Analysis of Variance; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Extracellular Space; Homocysteine; Hypoxanthine; Hypoxanthines; Inosine; Male; Rats; Rats, Wistar; S-Adenosylhomocysteine | 1993 |
Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Administration, Oral; Analysis of Variance; Animal Feed; Animals; Apoptosis; Cell Division; Deoxyuracil Nucleotides; Ethanol; Folic Acid; Homocysteine; Liver; Male; Methionine; Proliferating Cell Nuclear Antigen; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Thymine Nucleotides | 1996 |
Effects on transmethylation by high-dose 6-mercaptopurine and methotrexate infusions during consolidation treatment of acute lymphoblastic leukemia.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Erythrocytes; Homocysteine; Humans; Mercaptopurine; Methionine; Methotrexate; Methylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purine Nucleotides; S-Adenosylhomocysteine; S-Adenosylmethionine | 1996 |
Effect of methionine loading on 5-methyltetrahydrofolate, S-adenosylmethionine and S-adenosylhomocysteine in plasma of healthy humans.
Topics: Adult; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Kinetics; Male; Methionine; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 1996 |
Apoptosis and transmethylation metabolites in HL-60 cells.
Topics: Adenosine; Apoptosis; DNA; DNA Fragmentation; Enzyme Inhibitors; HL-60 Cells; Homocysteine; Humans; Methylation; Methyltransferases; Nucleic Acid Synthesis Inhibitors; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1996 |
Effect of L-Dopa and the catechol-O-methyltransferase inhibitor Ro 41-0960 on sulfur amino acid metabolites in rats.
Topics: Animals; Benzophenones; Brain; Catechol O-Methyltransferase Inhibitors; Cerebellum; Cerebral Cortex; Corpus Striatum; Enzyme Inhibitors; Hippocampus; Homocysteine; Kidney; Levodopa; Liver; Male; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 1997 |
Determinants of the S-adenosylhomocysteine (SAH) technique for the local assessment of cardiac free cytosolic adenosine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cytosol; Dogs; Heart; Homocysteine; Hydrolases; Myocardium; S-Adenosylhomocysteine | 1997 |
Influence of oral S-adenosylmethionine on plasma 5-methyltetrahydrofolate, S-adenosylhomocysteine, homocysteine and methionine in healthy humans.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Administration, Oral; Adult; Female; Homocysteine; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases; Reference Values; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 1997 |
Inhibition of growth and p21ras methylation in vascular endothelial cells by homocysteine but not cysteine.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Division; Cell Membrane; Cells, Cultured; Cysteine; DNA; Endothelium, Vascular; Flow Cytometry; G1 Phase; Guanosine Diphosphate; Guanosine Triphosphate; Homocysteine; Humans; Kinetics; Methylation; Muscle, Smooth, Vascular; Proto-Oncogene Proteins p21(ras); S-Adenosylhomocysteine; Time Factors; Umbilical Veins | 1997 |
Enzyme conversion immunoassay for determining total homocysteine in plasma or serum.
Topics: Adenosylhomocysteinase; Antibodies, Monoclonal; Binding, Competitive; Enzyme-Linked Immunosorbent Assay; Homocysteine; Humans; Hydrolases; S-Adenosylhomocysteine | 1998 |
Evidence for disturbed S-adenosylmethionine : S-adenosylhomocysteine ratio in patients with end-stage renal failure: a cause for disturbed methylation reactions?
Topics: Adult; Aged; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylation; Middle Aged; Models, Biological; Renal Dialysis; S-Adenosylhomocysteine; S-Adenosylmethionine | 1998 |
In vitro methylation of arsenite by rabbit liver cytosol: effect of metal ions, metal chelating agents, methyltransferase inhibitors and uremic toxins.
Topics: Animals; Arsenites; Cresols; Cytosol; Edetic Acid; Enzyme Inhibitors; Homocysteine; Hypoxanthine; In Vitro Techniques; Inositol; Liver; Male; Metals, Heavy; Methylation; Oxalates; Pyrogallol; Rabbits; Radioisotopes; S-Adenosylhomocysteine; Substrate Specificity; Uremia | 1999 |
Evaluation of the Abbott IMx fluorescence polarization immunoassay and the bio-rad enzyme immunoassay for homocysteine: comparison with high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Fluorescence Polarization; Homocysteine; Humans; Immunoassay; Reagent Kits, Diagnostic; Regression Analysis; Reproducibility of Results; S-Adenosylhomocysteine; Sensitivity and Specificity | 2000 |
Interrelations between plasma homocysteine and intracellular S-adenosylhomocysteine.
Topics: Adult; Aged; Animals; Case-Control Studies; Chromatography, High Pressure Liquid; Erythrocytes; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Tissue Distribution; Vascular Diseases | 2000 |
Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylation.
Topics: Adult; DNA Methylation; Female; Homocysteine; Humans; Lymphocytes; Metabolic Diseases; Middle Aged; S-Adenosylhomocysteine | 2000 |
Disturbed ratio of erythrocyte and plasma S-adenosylmethionine/S-adenosylhomocysteine in peripheral arterial occlusive disease.
Topics: Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Erythrocytes; Female; Hematocrit; Homocysteine; Humans; Kidney; Male; Middle Aged; Odds Ratio; Reference Values; S-Adenosylhomocysteine; S-Adenosylmethionine | 2001 |
Quantitative integration of different sites of adenosine metabolism in the heart.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Binding, Competitive; Biological Transport; Blood Flow Velocity; Cell Membrane; Cells, Cultured; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Guinea Pigs; Homocysteine; In Vitro Techniques; Models, Cardiovascular; Muscle, Smooth, Vascular; Myocardium; S-Adenosylhomocysteine; Thioinosine | 2000 |
Plasma proteins containing damaged L-isoaspartyl residues are increased in uremia: implications for mechanism.
Topics: Aspartic Acid; Biomarkers; Blood Proteins; Chromatography, High Pressure Liquid; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Renal Dialysis; S-Adenosylhomocysteine; Serum Albumin; Uremia | 2001 |
Homocysteine metabolism in children with Down syndrome: in vitro modulation.
Topics: Adenosine; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cystathionine beta-Synthase; Cysteine; DNA Methylation; Down Syndrome; Glutathione; Homocysteine; Humans; Leucovorin; Lymphocytes; Methionine; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Superoxide Dismutase; Thymidine; Vitamin B 12 | 2001 |
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.
Topics: Animals; Aorta; Brain; Chronic Disease; Cystathionine beta-Synthase; Disease Models, Animal; Endothelium, Vascular; Folic Acid; Food, Fortified; Heterozygote; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine; Thrombomodulin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2001 |
Blood determinations of S-adenosylmethionine, S-adenosylhomocysteine, and homocysteine: correlations with diet.
Topics: Body Mass Index; Diet; Dietary Fats; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Neoplasms; Pyridoxine; Reference Values; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine | 2001 |
A new caffeine biosynthetic pathway in tea leaves: utilisation of adenosine released from the S-adenosyl-L-methionine cycle.
Topics: Adenosine; Adenosylhomocysteinase; Caffeine; Carbon Dioxide; Cell Extracts; Chloroplasts; Homocysteine; Hydrolases; Methionine Adenosyltransferase; Methylation; Plant Leaves; S-Adenosylhomocysteine; S-Adenosylmethionine; Tea; Theobromine | 2001 |
Increasing levels of dietary homocystine with carotid endarterectomy produced proportionate increases in plasma homocysteine and intimal hyperplasia.
Topics: Animals; Carotid Arteries; Cystathionine beta-Synthase; Endarterectomy, Carotid; Homocysteine; Homocystine; Hyperplasia; Liver; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Rats; Rats, Sprague-Dawley; Recurrence; S-Adenosylhomocysteine; S-Adenosylmethionine; Tunica Intima | 2001 |
Intracellular S-adenosylhomocysteine concentrations predict global DNA hypomethylation in tissues of methyl-deficient cystathionine beta-synthase heterozygous mice.
Topics: Analysis of Variance; Animals; Body Weight; Brain; Cystathionine beta-Synthase; Diet; DNA Methylation; Genotype; Homocysteine; Kidney; Liver; Mice; S-Adenosylhomocysteine | 2001 |
Plasma S-adenosylhomocysteine is a more sensitive indicator of cardiovascular disease than plasma homocysteine.
Topics: Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Sensitivity and Specificity; Vitamin B 12 | 2001 |
Tissue levels of S-adenosylhomocysteine in the rat kidney: effects of ischemia and homocysteine.
Topics: Adenosine; Animals; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Ischemia; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2002 |
The effect of troglitazone on plasma homocysteine, hepatic and red blood cell S-adenosyl methionine, and S-adenosyl homocysteine and enzymes in homocysteine metabolism in Zucker rats.
Topics: Animals; Chromans; Cystathionine beta-Synthase; Erythrocytes; Female; Homocysteine; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Methylenetetrahydrofolate Reductase (NADPH2); Obesity; Oxidoreductases Acting on CH-NH Group Donors; Rats; Rats, Zucker; S-Adenosylhomocysteine; S-Adenosylmethionine; Thiazoles; Thiazolidinediones; Thinness; Troglitazone | 2002 |
S-adenosylhomocysteine, but not homocysteine, is toxic to yeast lacking cystathionine beta-synthase.
Topics: Chromatography, High Pressure Liquid; Culture Media; Cystathionine beta-Synthase; Homocysteine; Homocystinuria; Humans; S-Adenosylhomocysteine; S-Adenosylmethionine; Yeasts | 2002 |
In the cystathionine beta-synthase knockout mouse, elevations in total plasma homocysteine increase tissue S-adenosylhomocysteine, but responses of S-adenosylmethionine and DNA methylation are tissue specific.
Topics: Animals; Base Sequence; Cystathionine beta-Synthase; DNA; DNA Methylation; DNA Primers; Genotype; Homocysteine; Mice; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine | 2002 |
Elevation in S-adenosylhomocysteine and DNA hypomethylation: potential epigenetic mechanism for homocysteine-related pathology.
Topics: Animals; Chronic Disease; DNA Methylation; Homocysteine; Humans; S-Adenosylhomocysteine | 2002 |
Acute valproate administration impairs methionine metabolism in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Anticonvulsants; Betaine-Homocysteine S-Methyltransferase; Female; Folic Acid; Glutathione; Glutathione Disulfide; Homocysteine; Liver; Methionine; Methionine Adenosyltransferase; Methyltransferases; Models, Animal; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Teratogens; Valproic Acid; Vitamin B 6 | 2002 |
Remethylation and transsulfuration of methionine in cirrhosis: studies with L-[H3-methyl-1-C]methionine.
Topics: Adult; Carbon Isotopes; Homocysteine; Humans; Kinetics; Liver Cirrhosis, Alcoholic; Male; Methionine; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tritium | 2002 |
The effect of dietary folate on genomic and p53-specific DNA methylation in rat colon.
Topics: Animals; Body Weight; Colon; Dietary Supplements; DNA Methylation; Folic Acid; Genome; Hemoglobins; Homocysteine; Rats; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Tumor Suppressor Protein p53 | 2003 |
Anthocyanin administration elevates plasma homocysteine in rats.
Topics: Animals; Anthocyanins; Female; Homocysteine; Kidney; Liver; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2002 |
Increased homocysteine and S-adenosylhomocysteine concentrations and DNA hypomethylation in vascular disease.
Topics: Cardiovascular Diseases; DNA Methylation; Homocysteine; Humans; Male; Middle Aged; S-Adenosylhomocysteine | 2003 |
Dietary folate and selenium affect dimethylhydrazine-induced aberrant crypt formation, global DNA methylation and one-carbon metabolism in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Antioxidants; Carbon; Carcinogens; Colon; Cystathionine beta-Synthase; Deficiency Diseases; Diet; Dimethylhydrazines; Disease Susceptibility; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Interactions; Folic Acid; Glutathione; Homocysteine; Injections, Intraperitoneal; Liver; Male; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; Selenium | 2003 |
BIOSYNTHESIS OF CYCLOPROPANE COMPOUNDS. VI. PRODUCT INHIBITION OF CYCLOPROPANE FATTY ACID SYNTHETASE BY S-ADENOSYLHOMOCYSTEINE AND REVERSAL OF INHIBITION BY A HYDROLYTIC ENZYME.
Topics: Chemical Phenomena; Chemistry; Chromatography; Clostridium; Cyclopropanes; Fatty Acids; Homocysteine; Hydrolases; Ligases; Methyltransferases; Phospholipids; Research; S-Adenosylhomocysteine | 1964 |
Increased plasma homocysteine and S-adenosylhomocysteine and decreased methionine is associated with altered phosphatidylcholine and phosphatidylethanolamine in cystic fibrosis.
Topics: Child; Cystic Fibrosis; Female; Homocysteine; Humans; Male; Methionine; Phosphatidylcholines; Phosphatidylethanolamines; S-Adenosylhomocysteine; Severity of Illness Index | 2003 |
A mathematical model of the methionine cycle.
Topics: Animals; Computational Biology; Cystathionine; Homocysteine; Methionine; Models, Biological; S-Adenosylhomocysteine; S-Adenosylmethionine | 2004 |
Improved rotorod performance and hyperactivity in mice deficient in a protein repair methyltransferase.
Topics: Age Factors; Aging; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Diet, Reducing; Exploratory Behavior; Genotype; Homocysteine; Hyperkinesis; Mice; Mice, Knockout; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Rotarod Performance Test; S-Adenosylhomocysteine; S-Adenosylmethionine; Stereotyped Behavior; Survival Rate; Time Factors | 2004 |
Increased homocysteine and decreased adenosine formation in Alzheimer's disease.
Topics: Adenosine; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cerebrovascular Disorders; Down-Regulation; Female; Homocysteine; Humans; Intracranial Arteriosclerosis; Male; Middle Aged; Neuroprotective Agents; Predictive Value of Tests; S-Adenosylhomocysteine; Up-Regulation | 2004 |
Homocysteine clearance and methylation flux rates in health and end-stage renal disease: association with S-adenosylhomocysteine.
Topics: Adult; Aged; Case-Control Studies; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur | 2004 |
3-Deazaadenosine, a stabilizer of whole-blood homocysteine content, does not interfere with the single-enzyme homocysteine assay while totally inhibiting the enzyme conversion homocysteine immunoassay.
Topics: Homocysteine; Humans; Immunoenzyme Techniques; Lyases; S-Adenosylhomocysteine; Tubercidin | 2004 |
Modulation of methyl group metabolism by streptozotocin-induced diabetes and all-trans-retinoic acid.
Topics: Animals; Cystathionine beta-Synthase; Diabetes Mellitus, Experimental; Glycine N-Methyltransferase; Homocysteine; Male; Methyltransferases; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Streptozocin; Tretinoin | 2004 |
S-adenosylhomocysteine sensitizes to TNF-alpha hepatotoxicity in mice and liver cells: a possible etiological factor in alcoholic liver disease.
Topics: Adenosine; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Caspase 8; Caspases; Cell Line, Tumor; Hepatocytes; Homocysteine; Humans; Liver Diseases, Alcoholic; Methylation; Mice; Mice, Inbred C57BL; NF-kappa B; S-Adenosylhomocysteine; Tumor Necrosis Factor-alpha | 2004 |
Low ratio of S-adenosylmethionine to S-adenosylhomocysteine is associated with vitamin deficiency in Brazilian pregnant women and newborns.
Topics: Adult; Birth Weight; Brazil; Female; Fetal Blood; Gestational Age; Homocysteine; Humans; Infant, Newborn; Pregnancy; ROC Curve; S-Adenosylhomocysteine; S-Adenosylmethionine; Social Class; Vitamin B 12 Deficiency | 2004 |
Nucleosides XI. Synthesis and antiviral evaluation of 5'-alkylthio-5'-deoxy quinazolinone nucleoside derivatives as S-adenosyl-L-homocysteine analogs.
Topics: Antiviral Agents; Homocysteine; Indicators and Reagents; Magnetic Resonance Spectroscopy; Nucleosides; Quinazolines; S-Adenosylhomocysteine; Spectrometry, Mass, Fast Atom Bombardment | 2004 |
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2004 |
Dual effect of DL-homocysteine and S-adenosylhomocysteine on brain synthesis of the glutamate receptor antagonist, kynurenic acid.
Topics: Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Down-Regulation; Excitatory Amino Acid Antagonists; Female; Hippocampus; Homocysteine; Kynurenic Acid; Leucine; Male; Organ Culture Techniques; Phenylalanine; Rabbits; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Metabotropic Glutamate; S-Adenosylhomocysteine; Sulfhydryl Compounds; Transaminases; Up-Regulation | 2005 |
Congenital heart defects and abnormal maternal biomarkers of methionine and homocysteine metabolism.
Topics: Adult; Arkansas; Biomarkers; Case-Control Studies; Female; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Life Style; Methionine; Pregnancy; Registries; Risk Factors; S-Adenosylhomocysteine | 2005 |
Phosphatidylcholine and lysophosphatidylcholine excretion is increased in children with cystic fibrosis and is associated with plasma homocysteine, S-adenosylhomocysteine, and S-adenosylmethionine.
Topics: Case-Control Studies; Child; Choline Deficiency; Cross-Sectional Studies; Cystic Fibrosis; Diet Records; Dietary Fats; Feces; Female; Homocysteine; Humans; Intestinal Absorption; Lysophosphatidylcholines; Male; Phosphatidylcholines; S-Adenosylhomocysteine; S-Adenosylmethionine | 2005 |
Homocysteine alterations in experimental cholestasis and its subsequent cirrhosis.
Topics: Analysis of Variance; Animals; Bile Ducts; Cholestasis; Cysteine; Glutathione; Homocysteine; Ligation; Liver; Liver Cirrhosis, Biliary; Male; Methionine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 2005 |
Disturbed homocysteine and methionine cycle intermediates S-adenosylhomocysteine and S-adenosylmethionine are related to degree of renal insufficiency in type 2 diabetes.
Topics: Aged; Cystathionine; Cysteine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Folic Acid; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Male; Methionine; Methylmalonic Acid; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcobalamins; Vitamin B 12; Vitamin B 6 | 2005 |
Homocysteine, a risk factor for atherosclerosis, biphasically changes the endothelial production of kynurenic acid.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Excitatory Amino Acid Antagonists; Glycine; Homocysteine; In Vitro Techniques; Injections, Intraperitoneal; Kynurenic Acid; Leucine; Male; Methionine; Phenylalanine; Pipecolic Acids; Rats; Rats, Wistar; Risk Factors; S-Adenosylhomocysteine | 2005 |
Inhibition of transmethylation disturbs neurulation in chick embryos.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Chick Embryo; Cycloleucine; Dose-Response Relationship, Drug; Drug Interactions; Embryonic Development; Homocysteine; Methylation; Models, Biological; Nervous System; Organogenesis; S-Adenosylhomocysteine; Time Factors; Tubercidin | 2005 |
Congenital heart defects and maternal biomarkers of oxidative stress.
Topics: Adult; Arkansas; Biomarkers; Case-Control Studies; Dipeptides; Female; Folic Acid; Glutathione; Glutathione Disulfide; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Life Style; Oxidative Stress; Pregnancy; Pregnancy Complications; Registries; Risk Factors; S-Adenosylhomocysteine; Vitamin B 6 | 2005 |
Relationship between plasma S-adenosylhomocysteine concentration and glomerular filtration rate in children.
Topics: Adolescent; Child; Child, Preschool; Congenital Hypothyroidism; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Infant; Kidney Diseases; S-Adenosylhomocysteine; Vitamin B 12 | 2006 |
Maternal polymorphisms 677C-T and 1298A-C of MTHFR, and 66A-G MTRR genes: is there any relationship between polymorphisms of the folate pathway, maternal homocysteine levels, and the risk for having a child with Down syndrome?
Topics: Case-Control Studies; Down Syndrome; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Homocysteine; Humans; Infant; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Mutation; Polymorphism, Single Nucleotide; Regression Analysis; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine | 2006 |
Differential effects of dietary selenium (se) and folate on methyl metabolism in liver and colon of rats.
Topics: Animals; Colon; Deficiency Diseases; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Folic Acid; Glutathione; Glutathione Peroxidase; Glycine N-Methyltransferase; Homocysteine; Liver; Male; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Selenium | 2006 |
The 5th workshop on the assessment of adequate intake of dietary amino acids: general discussion 1.
Topics: Amino Acids; Animals; Creatine; Cysteine; Diet; Glutathione; Homocysteine; Humans; Methionine; Nutritional Requirements; S-Adenosylhomocysteine; S-Adenosylmethionine | 2006 |
Exogenous glycine partially attenuates homocysteine-induced apoptosis and membrane peroxidation in chick embryos.
Topics: Animals; Apoptosis; Brain; Brain Chemistry; Caspase 3; Caspases; Chick Embryo; Fatty Acids; Glycine; Homocysteine; Lipid Peroxides; Liver; Membranes; S-Adenosylhomocysteine; S-Adenosylmethionine | 2006 |
Suppression of methionine-induced hyperhomocysteinemia by dietary eritadenine in rats.
Topics: Adenine; Animals; Cystathionine beta-Synthase; Diet; Dose-Response Relationship, Drug; Enzyme Activation; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 2006 |
Analytical evaluation of a new immunonephelometric method for homocysteine measurement.
Topics: Adenosylhomocysteinase; Adult; Aged; Chromatography, High Pressure Liquid; Dithiothreitol; Female; Homocysteine; Humans; Immunoassay; Male; Middle Aged; Nephelometry and Turbidimetry; Reproducibility of Results; S-Adenosylhomocysteine; Thyroglobulin | 2007 |
Intracellular levels of S-adenosylhomocysteine but not homocysteine are highly correlated to the expression of nm23-H1 and the level of 5-methyldeoxycytidine in human hepatoma cells with different invasion activities.
Topics: Cell Line, Tumor; Deoxycytidine; DNA Methylation; Down-Regulation; Homocysteine; Humans; Liver Neoplasms; Neoplasm Invasiveness; S-Adenosylhomocysteine | 2006 |
Role of S-adenosylhomocysteine hydrolase in adenosine-induced apoptosis in HepG2 cells.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosylhomocysteinase; Apoptosis; Caspase Inhibitors; Caspases; Dipyridamole; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Homocysteine; Humans; Methylation; Nucleoside Transport Proteins; Oligonucleotide Array Sequence Analysis; Pentostatin; Proto-Oncogene Proteins c-mdm2; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Effect of vitamin B6 deficiency on S-adenosylhomocysteine hydrolase activity as a target point for methionine metabolic regulation.
Topics: Adenosylhomocysteinase; Analysis of Variance; Animals; Body Weight; Homocysteine; Liver; Male; Methionine; Random Allocation; Rats; Rats, Wistar; S-Adenosylhomocysteine; Vitamin B Deficiency | 2006 |
Elevated serum S-adenosylhomocysteine in cobalamin-deficient megaloblastic anemia.
Topics: Adult; Aged; Anemia, Megaloblastic; Female; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; S-Adenosylhomocysteine; Vitamin B 12 Deficiency | 2007 |
Synergistic effects of S-adenosylhomocysteine and homocysteine on DNA damage in a murine microglial cell line.
Topics: Animals; Cell Line; DNA; DNA Damage; DNA Methylation; Drug Synergism; Free Radical Scavengers; Homocysteine; Hydrogen Peroxide; Mice; Microglia; Reactive Oxygen Species; S-Adenosylhomocysteine; Uracil | 2007 |
Increase in S-adenosylhomocysteine content and its effect on the S-adenosylhomocysteine hydrolase activity under transient high plasma homocysteine levels in rats.
Topics: Adenosylhomocysteinase; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Homocysteine; Infusions, Intravenous; Liver; Male; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Sodium Chloride | 2006 |
DNA methylation status is not impaired in treated cystathionine beta-synthase (CBS) deficient patients.
Topics: Chromatography, Liquid; Cystathionine beta-Synthase; DNA; DNA Methylation; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Analysis, DNA; Spectrometry, Mass, Electrospray Ionization | 2007 |
Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase.
Topics: Animals; Brain; Disease Models, Animal; Embryo, Mammalian; Female; Ferredoxin-NADP Reductase; Folic Acid; Heart; Homocysteine; Hyperhomocysteinemia; Kidney; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Folate status and S-adenosylmethionine/S-adenosylhomocysteine ratio in colorectal adenocarcinoma in humans.
Topics: Adenocarcinoma; Aged; Colon; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Intestinal Mucosa; Male; Nutritional Status; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
Supranormal dietary folic acid supplementation: effects on methionine metabolism in weanling rats.
Topics: Animals; Biomarkers; Dietary Supplements; DNA Methylation; Folic Acid; Homocysteine; Liver; Male; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamins; Weaning | 2007 |
Homocysteine affects cardiomyocyte viability: concentration-dependent effects on reversible flip-flop, apoptosis and necrosis.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Caspase 3; Cell Membrane; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression Regulation; Homocysteine; Membrane Fluidity; Membrane Glycoproteins; Membrane Potential, Mitochondrial; Mitochondria, Heart; Models, Biological; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Necrosis; Phospholipids; Protein Processing, Post-Translational; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Association between decreased vitamin levels and MTHFR, MTR and MTRR gene polymorphisms as determinants for elevated total homocysteine concentrations in pregnant women.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Alleles; Analysis of Variance; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Young Adult | 2008 |
Structure-based activity prediction for an enzyme of unknown function.
Topics: Adenine; Catalysis; Crystallography, X-Ray; Deamination; Deoxyadenosines; Enzymes; Homocysteine; Inosine; Models, Molecular; Nucleoside Deaminases; Protein Conformation; S-Adenosylhomocysteine; Structure-Activity Relationship; Substrate Specificity; Thermotoga maritima; Thionucleosides | 2007 |
Homocysteine-mediated expression of SAHH, DNMTs, MBD2, and DNA hypomethylation potential pathogenic mechanism in VSMCs.
Topics: Adenosylhomocysteinase; Atherosclerosis; Base Sequence; Blotting, Western; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA-Binding Proteins; Enzyme Induction; Homocysteine; Humans; Molecular Sequence Data; Muscle, Smooth, Vascular; Polymerase Chain Reaction; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes.
Topics: Animals; Apolipoproteins B; Betaine; Betaine-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Fatty Liver; Gene Transfer Techniques; Hepatocytes; Homocysteine; Humans; Lipid Metabolism; Liver Neoplasms; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Sterol Regulatory Element Binding Protein 1 | 2007 |
Influence of preconditioning-like hypoxia on the liver of developing methyl-deficient rats.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Proliferation; Choline Deficiency; Cystathionine beta-Synthase; Female; Folic Acid; Folic Acid Deficiency; Food, Formulated; Glutathione; Homocysteine; Hypoxia; Liver; Nitric Oxide Synthase Type II; Pregnancy; Rats; Rats, Wistar; Riboflavin; Riboflavin Deficiency; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Deficiency | 2007 |
Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver.
Topics: Alanine Transaminase; Animals; ATPases Associated with Diverse Cellular Activities; Chromosome Mapping; Disease Models, Animal; Down-Regulation; Embryo, Mammalian; Female; Gene Expression; Gene Expression Profiling; Glycine N-Methyltransferase; Glycogen; Glycogen Storage Disease; Hepatitis, Chronic; Homocysteine; Liver; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Polymerase Chain Reaction; Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Homocysteine, S-adenosylmethionine and S-adenosylhomocysteine are associated with retinal microvascular abnormalities: the Hoorn Study.
Topics: Aged; Aged, 80 and over; Arterioles; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Folic Acid; Follow-Up Studies; Glucose Tolerance Test; Homocysteine; Humans; Male; Middle Aged; Retinal Diseases; Retinal Vessels; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
Ethanol-induced increased endogenous homocysteine levels and decreased ratios of SAM/SAH are only partially attenuated by exogenous glycine in developing chick brains.
Topics: Animals; Apoptosis; Brain; Caspase 3; Central Nervous System Depressants; Chick Embryo; Chickens; Down-Regulation; Embryonic Development; Enzyme Activation; Ethanol; Glycine; Homocysteine; S-Adenosylhomocysteine; S-Adenosylmethionine; Up-Regulation | 2008 |
Homocysteine-mediated PPARalpha,gamma DNA methylation and its potential pathogenic mechanism in monocytes.
Topics: Base Sequence; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Activation; Foam Cells; Homocysteine; Humans; Lipoproteins, LDL; Macrophage Activation; Molecular Sequence Data; Monocytes; PPAR alpha; PPAR gamma; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetradecanoylphorbol Acetate | 2008 |
Evaluation of nutritional and genetic determinants of total homocysteine, methylmalonic acid and S-adenosylmethionine/S-adenosylhomocysteine values in Brazilian childbearing-age women.
Topics: Adult; Aging; Alleles; Anemia, Iron-Deficiency; Avitaminosis; Brazil; Female; Genotype; Homocysteine; Humans; Methylmalonic Acid; Nutritional Physiological Phenomena; Polymorphism, Genetic; Reproduction; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamins | 2008 |
Plasma S-adenosylhomocysteine is a better biomarker of atherosclerosis than homocysteine in apolipoprotein E-deficient mice fed high dietary methionine.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Biomarkers; Body Weight; Diet; DNA Methylation; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Male; Methionine; Mice; S-Adenosylhomocysteine; Vitamin B 12; Vitamin B 6 | 2008 |
Stability of plasma homocysteine, S-adenosylmethionine, and S-adenosylhomocysteine in EDTA, acidic citrate, and Primavette collection tubes.
Topics: Adult; Aged; Aged, 80 and over; Blood Specimen Collection; Citrates; Edetic Acid; Homocysteine; Humans; Hydrogen-Ion Concentration; Middle Aged; Plasma; S-Adenosylhomocysteine; S-Adenosylmethionine; Temperature | 2007 |
Riboswitches that sense S-adenosylhomocysteine and activate genes involved in coenzyme recycling.
Topics: 5' Untranslated Regions; Base Sequence; Binding Sites; Coenzymes; Conserved Sequence; Gene Expression Regulation; Homocysteine; Kinetics; Methionine; Nucleic Acid Conformation; RNA; RNA, Bacterial; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
Plasma S-adenosylhomocysteine versus homocysteine as a marker for vascular disease.
Topics: Animals; Biomarkers; Homocysteine; Mice; S-Adenosylhomocysteine; Vascular Diseases | 2008 |
Hyperglycemia-induced membrane lipid peroxidation and elevated homocysteine levels are poorly attenuated by exogenous folate in embryonic chick brains.
Topics: Animals; Blood Glucose; Brain; Chick Embryo; Fatty Acids; Folic Acid; Glucose; Homocysteine; Lipid Peroxidation; Lipid Peroxides; Membrane Lipids; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
Elevated serum levels of S-adenosylhomocysteine, but not homocysteine, are associated with cardiovascular disease in stage 5 chronic kidney disease patients.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Chronic Disease; Female; Homocysteine; Humans; Kidney Diseases; Kidney Function Tests; Male; Middle Aged; Predictive Value of Tests; S-Adenosylhomocysteine; S-Adenosylmethionine; Sensitivity and Specificity; Severity of Illness Index | 2008 |
Neural tube defects and disturbed maternal folate- and homocysteine-mediated one-carbon metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Carbon; Case-Control Studies; Chi-Square Distribution; Chromatography; Female; Folic Acid; Homocysteine; Humans; Maternal Age; Models, Biological; Neural Tube Defects; Pregnancy; S-Adenosylhomocysteine | 2008 |
S-adenosyl-L-homocysteine hydrolase, key enzyme of methylation metabolism, regulates phosphatidylcholine synthesis and triacylglycerol homeostasis in yeast: implications for homocysteine as a risk factor of atherosclerosis.
Topics: Adenosylhomocysteinase; Atherosclerosis; Down-Regulation; Endoplasmic Reticulum; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Homeostasis; Homocysteine; Humans; Membrane Proteins; Methylation; Myo-Inositol-1-Phosphate Synthase; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Repressor Proteins; Risk Factors; S-Adenosylhomocysteine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Triglycerides | 2008 |
In vitro formation of homocysteine in whole blood in the presence of anticoagulants.
Topics: Anticoagulants; Blood Chemical Analysis; Catalysis; Citric Acid; Edetic Acid; Homocysteine; Humans; In Vitro Techniques; Iron; Methionine; S-Adenosylhomocysteine | 2008 |
Epigenetic alterations in the brains of Fisher 344 rats induced by long-term administration of folate/methyl-deficient diet.
Topics: Animals; Brain; Diet, Reducing; DNA Modification Methylases; DNA-Binding Proteins; Epigenesis, Genetic; Folic Acid Deficiency; Homocysteine; Male; Methionine; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Regulatory Factor X Transcription Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Transcription Factors | 2008 |
Relationships between gene polymorphisms of folate-related proteins and vitamins and metabolites in pregnant women and neonates.
Topics: Adult; Brazil; DNA; Embryonic Development; Ethnicity; Female; Folic Acid; Glutamate Carboxypeptidase II; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Pregnancy; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylhomocysteine; S-Adenosylmethionine; Socioeconomic Factors; Vitamin B 12; Vitamin B Complex; Young Adult | 2008 |
Methionine metabolism in an animal model of sepsis.
Topics: Animals; Cysteine; Disease Models, Animal; Glutathione; Homocysteine; Lipopolysaccharides; Male; Methionine; Oxidation-Reduction; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Sepsis | 2008 |
Experimental folate and vitamin B12 deficiency does not alter bone quality in rats.
Topics: Animals; Biomarkers; Biomechanical Phenomena; Body Weight; Bone and Bones; Bone Remodeling; Disease Models, Animal; Female; Folic Acid Deficiency; Homocysteine; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2009 |
Hyperhomocysteinemia induces a tissue specific accumulation of homocysteine in bone by collagen binding and adversely affects bone.
Topics: Aged; Animals; Bone and Bones; Collagen; Female; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Methionine; Myocardium; Osteoporosis; Porosity; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Stress, Mechanical | 2009 |
Hypohomocysteinemic effect of cysteine is associated with increased plasma cysteine concentration in rats fed diets low in protein and methionine levels.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Caseins; Choline; Cystathionine beta-Synthase; Cysteic Acid; Cysteine; Diet, Protein-Restricted; Dietary Supplements; Glycine; Homocysteine; Hyperhomocysteinemia; Male; Mercaptoethylamines; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; Soybean Proteins | 2009 |
Hepatic cystathionine beta-synthase activity does not increase in response to methionine supplementation in rats fed a low casein diet: association with plasma homocysteine concentrations.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Caseins; Cystathionine beta-Synthase; Cysteine; Dietary Proteins; Dietary Supplements; Dose-Response Relationship, Drug; Energy Intake; Glycine; Homocysteine; Liver; Male; Methionine; Organ Size; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Weight Gain | 2009 |
Pilot study of association of anembryonic pregnancy with 55 elements in the urine, and serum level of folate, homocysteine and S-adenosylhomocysteine in Shanxi Province, China.
Topics: Adult; Case-Control Studies; China; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Multivariate Analysis; Nutritional Status; Pilot Projects; Pregnancy; Pregnancy Outcome; S-Adenosylhomocysteine; Trace Elements; Urine; Young Adult | 2009 |
Methylation status and neurodegenerative markers in Parkinson disease.
Topics: Aged; alpha-Synuclein; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Biomarkers; Blood Platelets; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Nerve Degeneration; Parkinson Disease; Peptide Fragments; S-Adenosylhomocysteine; S-Adenosylmethionine; Substantia Nigra; Ultrasonography; Vitamin B 6 | 2009 |
Synergistic effects of homocysteine, S-adenosylhomocysteine and adenosine on apoptosis in BV-2 murine microglial cells.
Topics: Adenosine; Animals; Apoptosis; Caspase 3; Caspase 9; Cell Line; Cell Survival; Drug Synergism; Homocysteine; Methylation; Mice; Microglia; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; S-Adenosylhomocysteine | 2008 |
Body mass index is an important determinant of methylation biomarkers in women of reproductive ages.
Topics: Adult; Biomarkers; Body Mass Index; Female; Fertility; Folic Acid; Homocysteine; Humans; Life Style; Methylation; Middle Aged; Multivariate Analysis; Netherlands; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2009 |
Impaired transmethylation potential in Parkinson's disease patients treated with L-Dopa.
Topics: Aged; Antiparkinson Agents; Cross-Sectional Studies; Erythrocytes; Female; Genotype; Homocysteine; Humans; Levodopa; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Relationship of impairment induced by intracellular S-adenosylhomocysteine accumulation with DNA methylation in human umbilical vein endothelial cells treated with 3-deazaadenosine.
Topics: Apoptosis; Atherosclerosis; Cell Proliferation; Chemokine CCL2; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Endothelial Cells; Estrogen Receptor alpha; Gene Expression; Homocysteine; Humans; Infant, Newborn; Intracellular Membranes; L-Lactate Dehydrogenase; Microscopy, Electron; Promoter Regions, Genetic; RNA, Messenger; S-Adenosylhomocysteine; Superoxide Dismutase; Tubercidin; Umbilical Veins | 2009 |
Protective effect of isoflavones against homocysteine-mediated neuronal degeneration in SH-SY5Y cells.
Topics: Alzheimer Disease; Apoptosis; Cell Line, Tumor; Endoplasmic Reticulum; Homocysteine; Humans; Isoflavones; Nerve Degeneration; Neurons; Protective Agents; S-Adenosylhomocysteine | 2010 |
Regulation of homocysteine metabolism and methylation in human and mouse tissues.
Topics: Animals; Computational Biology; Enzymes; Gene Expression Profiling; Gene Expression Regulation; Homocysteine; Humans; Infant, Newborn; Metabolic Networks and Pathways; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
S-adenosylhomocysteine: a better marker of the development of Alzheimer's disease than homocysteine?
Topics: Alzheimer Disease; Animals; Biomarkers; Homocysteine; Humans; S-Adenosylhomocysteine | 2010 |
Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.
Topics: Amino Acids; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine beta-Synthase; Diet; Enzyme Inhibitors; Glycine N-Methyltransferase; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Letter to the editor: Is homocysteine the culprit molecule in vascular diseases or just a bystander?
Topics: Adipose Tissue; Animals; Cell Movement; Homocysteine; Humans; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; S-Adenosylhomocysteine; Vascular Diseases | 2010 |
Some more comments on 'folate deficiency in chronic pancreatitis'.
Topics: Folic Acid Deficiency; Glycine N-Methyltransferase; Homocysteine; Humans; Metabolic Networks and Pathways; Methionine; Pancreatitis, Chronic; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.
Topics: Carcinoma, Hepatocellular; Cysteine; Cytidine; DNA Methylation; DNA Modification Methylases; Gene Expression; Glycine N-Methyltransferase; Hep G2 Cells; Hepatocytes; Homeostasis; Homocysteine; Humans; Kinetics; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Osmolar Concentration; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
High bone concentrations of homocysteine are associated with altered bone morphology in humans.
Topics: Adult; Aged; Aged, 80 and over; Bone and Bones; Collagen; Extracellular Matrix; Female; Femur; Hip; Homocysteine; Humans; Male; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
A maternal dietary pattern characterised by fish and seafood in association with the risk of congenital heart defects in the offspring.
Topics: Adult; Biomarkers; Case-Control Studies; Feeding Behavior; Female; Fish Products; Heart Defects, Congenital; Homocysteine; Humans; Methylation; Netherlands; Odds Ratio; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Seafood; Surveys and Questionnaires; Vitamin B Complex | 2011 |
B-vitamin deficiency is protective against DSS-induced colitis in mice.
Topics: Analysis of Variance; Animals; Body Weight; Colitis; Dextran Sulfate; Gene Expression; Glutathione; Homocysteine; Inflammation; Interleukin-10; Kaplan-Meier Estimate; Male; Metabolomics; Methionine; Methylmalonic Acid; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Peroxidase; Pyridoxal Phosphate; S-Adenosylhomocysteine; Severity of Illness Index; Tumor Necrosis Factor-alpha; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2011 |
Homocysteine-induced cardiomyocyte apoptosis and plasma membrane flip-flop are independent of S-adenosylhomocysteine: a crucial role for nuclear p47(phox).
Topics: Adenosine; Adenosine Triphosphate; Animals; Apoptosis; Caspase 3; Cell Membrane; Cell Nucleus; Cell Survival; Extracellular Space; Homocysteine; Intracellular Space; Membrane Glycoproteins; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Phospholipid Transfer Proteins; Rats; Reactive Oxygen Species; S-Adenosylhomocysteine; S-Adenosylmethionine; Tyrosine | 2011 |
Adenosine kinase deficiency disrupts the methionine cycle and causes hypermethioninemia, encephalopathy, and abnormal liver function.
Topics: Adenosine Kinase; Adult; Amino Acid Metabolism, Inborn Errors; Brain Diseases; Child; Developmental Disabilities; Family Health; Female; Fibroblasts; Homocysteine; Humans; Liver Diseases; Male; Methionine; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
S-Adenosylhomocysteine induces apoptosis and phosphatidylserine exposure in endothelial cells independent of homocysteine.
Topics: Adenosine; Apoptosis; Caspase 3; Cell Survival; Cells, Cultured; Cytochromes c; Endothelial Cells; Enzyme Inhibitors; Homocysteine; Humans; Hydrogen Peroxide; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Onium Compounds; Phosphatidylserines; S-Adenosylhomocysteine; Tyrosine | 2012 |
Plasma homocysteine level and hepatic sulfur amino acid metabolism in mice fed a high-fat diet.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Amino Acids, Sulfur; Animals; Cardiovascular Diseases; Cystathionine beta-Synthase; Cysteine Dioxygenase; Diet, High-Fat; Dipeptides; Down-Regulation; Homocysteine; Lipid Peroxidation; Liver; Male; Methionine Adenosyltransferase; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides; Up-Regulation | 2013 |
The association between plasma homocysteine levels, methylation capacity and incident osteoporotic fractures.
Topics: Aged; Bone Density; Female; Homocysteine; Humans; Incidence; Linear Models; Methylation; Middle Aged; Netherlands; Osteoporotic Fractures; Proportional Hazards Models; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine | 2012 |
Relationships among biomarkers of one-carbon metabolism.
Topics: Adult; Aging; Biomarkers; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; One-Carbon Group Transferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Characteristics; Vitamin B 12; Young Adult | 2012 |
Biomarkers of the one-carbon pathway in association with congenital diaphragmatic hernia.
Topics: Adult; Biomarkers; Birth Weight; Female; Fetal Blood; Gestational Age; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Homocysteine; Humans; Infant, Newborn; Male; Regression Analysis; S-Adenosylhomocysteine; S-Adenosylmethionine | 2012 |
Determinants of the essential one-carbon metabolism metabolites, homocysteine, S-adenosylmethionine, S-adenosylhomocysteine and folate, in cerebrospinal fluid.
Topics: Adult; Aged; Aging; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Immunoassay; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry; Vitamin B 12 | 2012 |
The comprehensive effects of hyperlipidemia and hyperhomocysteinemia on pathogenesis of atherosclerosis and DNA hypomethylation in ApoE-/- mice.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cholesterol; Cholesterol, Dietary; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Gene Expression; Homocysteine; Hyperhomocysteinemia; Hyperlipidemias; Lipids; Male; Methionine; Mice; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2012 |
A fluorescence-based assay for the measurement of S-adenosylhomocysteine hydrolase activity in biological samples.
Topics: Adenosine; Adenosylhomocysteinase; Biological Assay; Fluorescence; HeLa Cells; Homocysteine; Humans; S-Adenosylhomocysteine | 2013 |
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 2013 |
Tissue-specific relationship of S-adenosylhomocysteine with allele-specific H19/Igf2 methylation and imprinting in mice with hyperhomocysteinemia.
Topics: Alleles; Animals; Base Sequence; Body Weight; Brain; Crosses, Genetic; Diet; DNA Methylation; Female; Genetic Loci; Genomic Imprinting; Homocysteine; Hyperhomocysteinemia; Insulin-Like Growth Factor II; Liver; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Organ Specificity; RNA, Long Noncoding; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity | 2013 |
LC-MS/MS identification of the one-carbon cycle metabolites in human plasma.
Topics: Adult; Chromatography, Liquid; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Multiple Sclerosis; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry | 2013 |
Methylation metabolism in sepsis and systemic inflammatory response syndrome.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; DNA Methylation; Female; Homocysteine; Humans; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sepsis; Systemic Inflammatory Response Syndrome; Young Adult | 2013 |
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult | 2013 |
A novel role of the tumor suppressor GNMT in cellular defense against DNA damage.
Topics: Adenosine; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleus; Cells, Cultured; Chromatography, High Pressure Liquid; Dietary Supplements; DNA Damage; DNA Methylation; Female; Fluorescent Antibody Technique, Indirect; Folic Acid; Glycine N-Methyltransferase; Hepatocytes; Homocysteine; Humans; Liver; Liver Neoplasms; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Knockout; Minor Histocompatibility Antigens; Protein Transport; Purines; Pyrimidines; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Uracil | 2014 |
Levels of key enzymes of methionine-homocysteine metabolism in preeclampsia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Female; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Plasma homocysteine, methionine and S-adenosylhomocysteine levels following high-dose methotrexate treatment in pediatric patients with acute lymphoblastic leukemia or Burkitt lymphoma: association with hepatotoxicity.
Topics: Antimetabolites, Antineoplastic; Burkitt Lymphoma; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; Homocysteine; Humans; Liver Function Tests; Male; Methionine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; S-Adenosylhomocysteine | 2014 |
Plasma sulfur amino acids and stearoyl-CoA desaturase activity in two Caucasian populations.
Topics: Adipose Tissue; Aged; Aged, 80 and over; Amino Acids, Sulfur; Cohort Studies; Cross-Sectional Studies; Cystathionine; Cysteine; Diet; Dipeptides; Exercise; Fatty Acids; Female; Glutathione; Homocysteine; Humans; Male; Methionine; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Stearoyl-CoA Desaturase; Surveys and Questionnaires; White People | 2013 |
Overexpression of S-adenosylhomocysteine hydrolase (SAHH) in esophageal squamous cell carcinoma (ESCC) cell lines: effects on apoptosis, migration and adhesion of cells.
Topics: Adenosylhomocysteinase; Apoptosis; Carcinoma, Squamous Cell; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Gene Expression; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; Homocysteine; Humans; Neoplasm Proteins; Protein Binding; Receptors for Activated C Kinase; Receptors, Cell Surface; S-Adenosylhomocysteine | 2014 |
Protein arginine hypomethylation in a mouse model of cystathionine β-synthase deficiency.
Topics: Animals; Arginine; Brain; Cystathionine beta-Synthase; Disease Models, Animal; DNA Methylation; Histones; Homocysteine; Homocystinuria; Liver; Methylation; Mice; S-Adenosylhomocysteine | 2014 |
S-adenosylhomocysteine is associated with subclinical atherosclerosis and renal function in a cardiovascular low-risk population.
Topics: Asymptomatic Diseases; Atherosclerosis; Cardiovascular Diseases; Female; Glomerular Filtration Rate; Homocysteine; Humans; Male; Middle Aged; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine | 2014 |
Folate and cobalamin modify associations between S-adenosylmethionine and methylated arsenic metabolites in arsenic-exposed Bangladeshi adults.
Topics: Adult; Aged; Arsenic; Arsenic Poisoning; Arsenicals; Bangladesh; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2014 |
Effect of vitamin B deprivation during pregnancy and lactation on homocysteine metabolism and related metabolites in brain and plasma of mice offspring.
Topics: Animals; Brain; Female; Folic Acid; Homocysteine; Lactation; Male; Mice; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamin B Deficiency | 2014 |
Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression.
Topics: Cell Adhesion; Endothelial Cells; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Leukocytes; Methylation; Methyltransferases; Oxidative Stress; RNA, Transfer, Amino Acyl; RNA, Transfer, Ser; S-Adenosylhomocysteine; S-Adenosylmethionine; Selenium; Selenoproteins | 2014 |
Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase.
Topics: Adenosine; Animals; Brain Chemistry; Drug Design; Enzyme Activation; Enzyme Inhibitors; Homocysteine; Hydrogen Bonding; Hydrolases; Inhibitory Concentration 50; Models, Molecular; Rats; S-Adenosylhomocysteine; Substrate Specificity | 2014 |
Aberrant DNA methylation of the PDGF gene in homocysteine‑mediated VSMC proliferation and its underlying mechanism.
Topics: Cell Proliferation; Cells, Cultured; DNA Methylation; Folic Acid; G1 Phase Cell Cycle Checkpoints; Homocysteine; Humans; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Promoter Regions, Genetic; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Umbilical Cord | 2014 |
Increased methylation demand exacerbates ethanol-induced liver injury.
Topics: Alcohol Drinking; Amidinotransferases; Animals; Chemical and Drug Induced Liver Injury; Diet; Ethanol; Fatty Liver, Alcoholic; Glycine; Guanidinoacetate N-Methyltransferase; Homocysteine; Liver; Male; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2014 |
Quantification of folate metabolites in serum using ultraperformance liquid chromatography tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Leucovorin; Limit of Detection; Neural Tube Defects; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry; Tetrahydrofolates | 2014 |
Whey protein supplementation increases methionine intake but not homocysteine plasma concentration in rats.
Topics: Advanced Oxidation Protein Products; Animals; Biomarkers; Caseins; Dietary Supplements; Glutathione; Homocysteine; Hyperhomocysteinemia; Lipid Peroxidation; Liver; Male; Methionine; Muscle, Skeletal; Oxidation-Reduction; Oxidative Stress; Random Allocation; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Whey Proteins | 2015 |
Plasma homocysteine and liver tissue S-adenosylmethionine, S-adenosylhomocysteine status in vitamin B6-deficient rats.
Topics: Animals; Glutathione Peroxidase; Glutathione Transferase; Homocysteine; Liver; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 6 Deficiency | 2015 |
Reversed phase and cation exchange liquid chromatography with spectrophotometric and elemental/molecular mass spectrometric detection for S-adenosyl methionine/S-adenosyl homocysteine ratios as methylation index in cell cultures of ovarian cancer.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Reverse-Phase; Cisplatin; DNA Methylation; Drug Resistance, Neoplasm; Female; Homocysteine; Humans; Methylation; Molecular Weight; Ovarian Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2015 |
Sulfur amino acid metabolism in Zucker diabetic fatty rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Animals; Area Under Curve; Betaine; Betaine-Homocysteine S-Methyltransferase; Cysteine; Dipeptides; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Homocysteine; Liver; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Rats; Rats, Zucker; S-Adenosylhomocysteine; S-Adenosylmethionine; Spermidine; Spermine; Taurine | 2015 |
Prospective study of telomere length and LINE-1 methylation in peripheral blood cells: the role of B vitamins supplementation.
Topics: Aged; Blood Cells; Calcium; Cross-Sectional Studies; Dietary Supplements; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Long Interspersed Nucleotide Elements; Male; Middle Aged; Prospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Telomere; Tetrahydrofolates; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin D | 2016 |
An enzyme captured in two conformational states: crystal structure of S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii.
Topics: Adenosine; Adenosylhomocysteinase; Bacterial Proteins; Binding Sites; Biocatalysis; Bradyrhizobium; Crystallography, X-Ray; Escherichia coli; Gene Expression; Homocysteine; Models, Molecular; NAD; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
Nucleoside Transport Inhibition by Dipyridamole Prevents Angiogenesis Impairment by Homocysteine and Adenosine.
Topics: Adenosine; Biological Transport, Active; Capillaries; Cell Line; Cell Movement; Cell Proliferation; Dipyridamole; Endothelial Cells; Homocysteine; Humans; MAP Kinase Signaling System; Neovascularization, Pathologic; Nucleosides; Phosphorylation; S-Adenosylhomocysteine; Vasodilator Agents; Wound Healing | 2015 |
Ratio of S-adenosylmethionine to S-adenosylhomocysteine as a sensitive indicator of atherosclerosis.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Biomarkers; Chemokine CCL2; Disease Models, Animal; DNA Methylation; Fatty Acid-Binding Proteins; Homocysteine; Interspersed Repetitive Sequences; Male; Mice; Mice, Knockout; Plaque, Atherosclerotic; S-Adenosylhomocysteine; S-Adenosylmethionine; Superoxide Dismutase | 2016 |
Lack of global epigenetic methylation defects in CBS deficient mice.
Topics: Animals; Cystathionine beta-Synthase; Disease Models, Animal; DNA; DNA Methylation; Epigenesis, Genetic; Epigenomics; Homocysteine; Homocystinuria; Kidney; Liver; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine | 2017 |
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium | 2016 |
Methionine Metabolites in Patients With Sepsis.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Catheter-Related Infections; Cohort Studies; Female; Homocysteine; Hospital Mortality; Humans; Intraabdominal Infections; Logistic Models; Male; Methionine; Middle Aged; Prognosis; Prospective Studies; Respiratory Tract Infections; S-Adenosylhomocysteine; S-Adenosylmethionine; Sepsis; Skin Diseases, Infectious; Urinary Tract Infections | 2018 |
Prolonged feeding with guanidinoacetate, a methyl group consumer, exacerbates ethanol-induced liver injury.
Topics: Alanine Transaminase; Amidinotransferases; Animals; Aspartate Aminotransferases; Body Weight; Calcium-Binding Proteins; Cholesterol; Dietary Supplements; DNA-Binding Proteins; Ethanol; Fatty Acids; Fatty Liver; Glycine; Guanidinoacetate N-Methyltransferase; Homocysteine; Inflammation; Insulin; Liver; Liver Diseases; Male; Nerve Tissue Proteins; Nucleobindins; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2016 |
A coupled photometric assay for characterization of S-adenosyl-l-homocysteine hydrolases in the physiological hydrolytic direction.
Topics: Adenosine Monophosphate; Adenosylhomocysteinase; Bradyrhizobium; Homocysteine; Hydrogen-Ion Concentration; Hydrolysis; Photometry; S-Adenosylhomocysteine; Temperature | 2017 |
Aberrant promoter methylation of multiple genes in VSMC proliferation induced by Hcy.
Topics: Alu Elements; Atherosclerosis; Cell Proliferation; CpG Islands; DNA Methylation; Epigenesis, Genetic; Female; GTP Phosphohydrolases; Homocysteine; Humans; Long Interspersed Nucleotide Elements; Mitochondrial Proteins; Models, Biological; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Primary Cell Culture; Promoter Regions, Genetic; PTEN Phosphohydrolase; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Suppressor Protein p53; Umbilical Veins | 2017 |
Acute exercise alters homocysteine plasma concentration in an intensity-dependent manner due increased methyl flux in liver of rats.
Topics: Animals; Body Weight; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine Adenosyltransferase; Methylation; Physical Conditioning, Animal; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Swimming | 2018 |
Folinic Acid Increases Protein Arginine Methylation in Human Endothelial Cells.
Topics: Arginine; Cells, Cultured; Dose-Response Relationship, Drug; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Leucovorin; Methionine; Methylation; Protein Processing, Post-Translational; S-Adenosylhomocysteine | 2018 |
The high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) may explain naked mole-rat's distinct methionine metabolite profile compared to mouse.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Enzyme Activation; Homocysteine; Homocystinuria; Methionine; Mice; Mole Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 2018 |
Fisher discriminant analysis for classification of autism spectrum disorders based on folate-related metabolism markers.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Autism Spectrum Disorder; Biomarkers; Case-Control Studies; Child; Child, Preschool; Discriminant Analysis; Female; Folic Acid; Homocysteine; Humans; Male; Polymorphism, Single Nucleotide; S-Adenosylhomocysteine; Tetrahydrofolates; Transcobalamins; Vitamin B 12 | 2019 |
Altered Methionine Metabolism in Cancer Cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Homocysteine; Humans; Methionine; Methylation; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine | 2019 |
Urine S-Adenosylmethionine are Related to Degree of Renal Insufficiency in Patients with Chronic Kidney Disease.
Topics: Adult; Aged; Aged, 80 and over; Female; Glomerular Filtration Rate; Homocysteine; Humans; Male; Middle Aged; Renal Insufficiency, Chronic; S-Adenosylhomocysteine; S-Adenosylmethionine | 2021 |
Intracellular homocysteine metabolites in SLE: plasma S-adenosylhomocysteine correlates with coronary plaque burden.
Topics: Adult; Aged; Female; Homocysteine; Humans; Leukocytes, Mononuclear; Lupus Erythematosus, Systemic; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine | 2021 |
Revisiting One-Carbon Metabolites in Human Breast Milk: Focus on S-Adenosylmethionine.
Topics: Adult; Carbon; Child; Chromatography, Liquid; Female; Homocysteine; Humans; Infant; Methionine; Milk, Human; Racemethionine; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry | 2023 |
NAD+ enhances the activity and thermostability of S-adenosyl-L-homocysteine hydrolase from Pyrococcus horikoshii OT3.
Topics: Homocysteine; Hydrolases; NAD; Pyrococcus horikoshii; S-Adenosylhomocysteine; S-Adenosylmethionine | 2023 |
ReACT (redox-activated chemical tagging) chemistry enables direct derivatization and fluorescence detection of
Topics: Fluorescence; Homocysteine; Methyltransferases; Oxidation-Reduction; S-Adenosylhomocysteine | 2023 |