homocysteine has been researched along with methylmalonic acid in 439 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (0.91) | 18.7374 |
1990's | 77 (17.54) | 18.2507 |
2000's | 175 (39.86) | 29.6817 |
2010's | 150 (34.17) | 24.3611 |
2020's | 33 (7.52) | 2.80 |
Authors | Studies |
---|---|
Lou, W; Yao, G; Yao, SL; Yao, SS; Yao, Y | 1 |
Allen, RH; Grigsby, J; Kaye, K; Kelly, JP; Lindenbaum, J; Matthews, LM; Pennypacker, LC; Stabler, SP | 1 |
McCully, KS | 1 |
Allen, RH; Brass, EP; Marcell, PD; Stabler, SP | 1 |
Refsum, H; Schneede, J; Slørdal, L; Svardal, A; Ueland, PM | 1 |
Beck, WS | 1 |
Baumgartner, R; Bubl, R; Kühne, T | 1 |
Allen, RH; Lindenbaum, J; Savage, DG; Stabler, SP | 4 |
Allen, RH; Kliegman, RM; Shenker, N; Shurin, S; Skidmore, MD | 1 |
Allen, RH; Brust, JC; Garrett, TJ; Healton, EB; Lindenbaum, J; Marcell, PD; Podell, ER; Savage, DG; Stabler, SP | 1 |
Hogenkamp, HP; Hrushesky, WJ; Roelofs, R; Trugman, J | 1 |
Bedros, AA; Carmel, R; Goodman, SI; Mace, JW | 1 |
Allen, RH; Joosten, E; Lindenbaum, J; Naurath, HJ; Riezler, R; Stabler, SP | 1 |
Gräsbeck, R; Hansen, M; Lindgren, A; Nexø, E; Rasmussen, K | 1 |
Bennett, M; Bottiglieri, T; Hyland, K; McGrath, K; Metz, J | 1 |
Conley, MR; Kirke, PN; Lee, YJ; McPartlin, JM; Mills, JL; Scott, JM; Weir, DG | 1 |
Bosley, TM; Campellone, JV; Malloy, TR | 1 |
Glueck, CJ; Lang, JE; Shaw, P; Sieve-Smith, L; Tracy, T; Wang, Y | 1 |
Bennie, A; Gangaidzo, I; Gwanzura, C; Kiire, C; Lindenbaum, J; Moyo, A; Mudenge, B; Mukiibi, JM; Savage, D; Sitima, J | 1 |
Dagnelie, PC; Refsum, H; Schneede, J; Ueland, PM; van Staveren, WA; Vollset, SE | 1 |
Daughtry, M; Galvez, N; Goodkin, DE; Green, R; Jacobsen, DW; Secic, M | 1 |
Brett, AS; Roberts, MS | 1 |
Allen, RH; Lindenbaum, J; Rosenberg, IH; Stabler, SP; Wilson, PW | 1 |
Allen, RH; Kolhouse, JF; Stabler, SP | 1 |
Criel, A; Devos, P; Goossens, W; Joosten, E; Lesaffre, E; Pelemans, W; Verhaeghe, R | 1 |
Guttormsen, AB; Refsum, H; Schneede, J; Ueland, PM | 1 |
Abrahm, JL; Allen, RH; Berry, GT; Chin, MM; Gracely, EJ; Stabler, SP; Sumner, AE | 1 |
Dybkjaer, L; Lyngbak, M; Møller, J; Pedersen, AM; Rasmussen, K | 1 |
Bose, S; Gilfix, B; Komorowski, R; Rosenblatt, DS; Seetharam, B; Seetharam, S | 1 |
Allen, RH; Lindenbaum, J; Stabler, SP | 4 |
Adjalla, C; Belleville, F; Benhayoun, S; Felden, F; Gaucher, P; Gelot, MA; Gerard, P; Guéant, JL; Lambert, D; Nicolas, JP; Renkes, P | 1 |
Rasmussen, K | 1 |
Allen, RH; Baumgartner, RN; Garry, PJ; Koehler, KM; Liang, HC; Pareo-Tubbeh, SL; Romero, LJ; Stabler, SP; Stauber, PM | 1 |
Kapadia, CR | 1 |
Leeming, RJ | 1 |
Joosten, E; Lesaffre, E; Riezler, R | 1 |
Berentsen, S; Talstad, I | 1 |
Azen, C; Carmel, R; Green, R; Howard, JM; Jacobsen, DW | 2 |
Adjalla, C; Belleville, F; Benhayoun, S; Felden, F; Gaucher, P; Gélot, MM; Gérard, P; Guéant, JL; Lambert, D; Nicolas, JP; Renkes, P | 1 |
Alm, B; Anderson, A; Fäldt, R; Gustafson, L; Hultberg, B; Nilsson, K; Nilsson, R; Vaara, I | 1 |
Dejaeger, E; Dereymaeker, L; Ghekiere, V; Joosten, E; Lesaffre, E; Pelemans, W; Riezler, R | 1 |
Delva, MD | 1 |
Allen, RH; Buccellato, FR; Lindenbaum, J; Lorenzini, EC; Morabito, A; Scalabrino, G; Tredici, G | 1 |
Adjalla, C; Beliah, M; Benhayoun, S; Gélot, MA; Guéant, JL; Lambert, D; Messing, B; Nicolas, JP; Thuillier, F | 1 |
Chanarin, I; Metz, J | 1 |
Bjerve, KS; Carlsen, SM; Følling, I; Grill, V; Refsum, H; Schneede, J | 1 |
Cicchetti, G; Marín, GH; Tentoni, J | 1 |
Johansson, KW; Kilander, AF; Lindgren, A; Nilsson, O; Swolin, B | 1 |
Christensen, L; Møller, J; Rasmussen, K | 2 |
Gérard, M; Ogier de Baulny, H; Saudubray, JM; Zittoun, J | 1 |
Abrahamsson, L; Friman, C; Nilsson, B; Norberg, B; Pettersson, T | 1 |
Sato, K | 1 |
Allen, RH; Del Giacco, EJ; Kuzminski, AM; Lindenbaum, J; Stabler, SP | 1 |
Bernard, MA; Kashner, TM; Nakonezny, PA | 1 |
Chadefaux-Vekemans, B; Garcia, MJ; Jakobs, C; Kamoun, P; Merinero, B; Pérez-Cerdá, C; Tonetti, C; Ugarte, M; Zittoun, J | 1 |
Kilander, AF; Lindgren, A; Lindstedt, G | 1 |
Hultdin, J | 1 |
Hølleland, G; Lund, PK; Refsum, H; Sandberg, S; Schneede, J; Ueland, PM | 1 |
Bagge, E; Kilander, A; Lindgren, A; Nexø, E | 1 |
Ambrosch, A; Dierkes, J; Domröse, U; Guttormsen, AB; Luley, C; Neumann, KH; Schneede, J | 1 |
Snow, CF | 1 |
Bächli, E; Fehr, J | 1 |
van den Ingh, TS; Vellema, P; Wouda, W | 1 |
Norberg, B | 2 |
Björkegren, K; Svärdsudd, K | 5 |
Allen, RH; Cohen, JA; Estacio, R; Jeffers, BW; Schrier, RW; Stabler, SP | 1 |
Bagge, E; Cederblad, A; Kilander, AF; Lindgren, A; Nilsson, O; Persson, H | 1 |
Azen, C; Carmel, R; Florea, M; Green, R; Jacobsen, DW; Rasmussen, K | 1 |
Allen, RH; Fried, LP; Guralnik, JM; Kittner, SJ; Pahor, M; Penninx, BW; Stabler, SP | 1 |
Graefe, U; Henning, BF; Langer, K; Raidt, H; Riezler, R; Tepel, M; Zidek, W | 1 |
Bar, J; Hod, M; Orvieto, R; Pardo, J; Peled, Y; Rafael, ZB; Sela, BA | 1 |
Dehlin, O; Hagberg, B; Hultberg, B; Jensen, E; Samuelsson, G; Svensson, T | 1 |
Stabler, SP | 2 |
Gustafson, L; Hultberg, B; Nilsson, K | 2 |
Allen, RH; Lindenbaum, J; Ogundipe, A; Savage, DG; Stabler, SP | 1 |
Allen, RH; Barbé, FM; Droesch, S; Gaire, D; Lambert, DA; Nicolas, JP; Sponne, IE; Stabler, SP | 1 |
Klee, GG | 1 |
Applegarth, DA; Hadorn, HB; Randak, C; Rolinski, B; Roscher, AA; Roschinger, W | 1 |
Fäldt, R; Gustafson, L; Hultberg, B; Nilsson, K; Warkentin, S | 1 |
Lindgren, A | 1 |
Bie, RB; Bolann, BJ; Grøttum, KA; Loraas, A; Refsum, H; Schjøth, A; Schneede, J; Solli, JD; Stallemo, A; Stokkeland, M; Ueland, PM | 1 |
Gustafson, L; Hultberg, B; Isaksson, A; Nilsson, K | 2 |
Bagnoli, F; Bellieni, CV; Buonocore, G; Cioni, M; De Felice, C; Farnetani, M; Ferrari, F; Gatti, MG | 1 |
Freedman, M; Garcia, A; Smith, M | 1 |
Cohen, AM; Gardyn, J; Mittelman, M; Sela, BA; Zlotnik, J | 1 |
Bodis, M; Geisel, J; Herrmann, W; Knapp, JP; Müller, A; Schorr, H; Stein, G | 1 |
Chin A Paw, MJ; de Groot, LC; de Jong, N; Kok, FJ; Rutten, RA; Swinkels, DW; van Staveren, WA | 1 |
Kirchgessner, M; Müller, H; Schwarz, FJ; Stangl, GI | 1 |
Allen, RH; Baumgartner, RN; Garry, PJ; Koehler, KM; Rimm, EB; Stabler, SP | 1 |
Hoffer, LJ; Kaplan, LN; Mamer, OA | 1 |
Aguirre Errasti, C | 1 |
Aguirre Errasti, C; Alonso Alonso, JJ; Barreiro García, G; Cánovas Fernández, A; de la Prieta López, R | 1 |
Ellegaard, J; Hvas, AM; Nexø, E | 2 |
Gadkari, M; Guttormsen, AB; Joglekar, A; Orning, L; Refsum, H; Sayyad, MG; Schneede, J; Ueland, PM; Ulvik, A; Vollset, SE; Yajnik, CS | 1 |
Hultdin, J; Lökk, J; Nilsson, M; Norberg, B; Sandström, H; Westman, G | 1 |
Bjørke Monsen, AL; Guttormsen, AB; Markestad, T; Refsum, H; Solheim, E; Ueland, PM; Vollset, SE | 1 |
Bailie, KE; Lappin, TR; McMullin, MF; Savage, GA; White, R; Young, PB | 1 |
Bodis, M; Geisel, J; Herrmann, W; Hübner, U; Knapp, JP; Schorr, H; Zimbelmann, I | 1 |
Geisel, J; Herrmann, W; Riegel, W; Schorr, H | 1 |
Naurath, HJ; Pütter, S; Riezler, R; Ubbink, JB | 1 |
Bondevik, GT; Kvåle, G; Lie, RT; Refsum, H; Schneede, J; Ulstein, M | 1 |
Baumgartner, ER; Bosk, A; Fowler, B; Heinemann, MK; Sieverding, L; Tomaske, M; Trefz, FK | 1 |
Allen, RH; Berthold, HK; Look, MP; Riezler, R; Rockstroh, JK; Sauerbruch, T; Schliefer, K; Stabler, SP | 1 |
Abrahamov, A; Algur, N; Elstein, D; Elstein, Y; Gielchinsky, Y; Green, R; Lahad, A; Miller, JW; Shinar, E; Zimran, A | 1 |
Bjørke Monsen, AL; Ueland, PM | 2 |
Ruaux, CG; Steiner, JM; Williams, DA | 1 |
Jonsson, O; Kilander, A; Lindgren, A; Olofsson, G; Ung, KA | 1 |
Bond, CM; Golden, MH; Rydlewicz, A; Simpson, JA; Taylor, RJ | 1 |
Schneede, J | 1 |
Hvas, AM; Nexø, E | 1 |
Page, RL; Ruscin, JM; Valuck, RJ | 1 |
Funamizu, M; Hata, A; Hayashi, K; Hiejima, Y; Hirayama, H; Kawabata, M; Makita, Y; Nakamura, T; Saionji, K; Tago, K; Tajiri, M; Takano, H | 1 |
Bale, A; Balling, R; Christensen, B; Colmenares, C; Ernest, S; Gilfix, BM; Hosack, A; Mamer, OA; McGrath, J; Nadeau, JH; Rodier, M; Rosenblatt, DS; Sankoff, D | 1 |
Biancheri, R; Caruso, U; Cerone, R; Minniti, G; Perrone, MV; Rossi, A; Schiaffino, MC; Tortori-Donati, P; Veneselli, E | 1 |
Abd-el-Gawa, G; Abrahamsson, K; Hanson, E; Hjälmås, K; Norlén, L | 1 |
Elian, KM; Hoffer, LJ | 1 |
Flynn, MA; Garrod, MG; Green, R; Miller, JW; Ramos, MI | 1 |
Day, A; Evans, L; Freedman, M; Garcia, A; Paris-Pombo, A | 1 |
Arnout, J; Baumgartner, ER; Fowler, B; Fryns, JP; Grünewald, S; Peters, H; Van Damme, B; Van Damme-Lombaerts, R; Van Hove, JL; Wevers, R | 1 |
Jacques, PF; Morris, MS; Rosenberg, IH; Selhub, J | 3 |
Abrahamsson, L; Ahola, L; Møller, J | 1 |
Herrmann, W; Jouma, M; Obeid, R | 2 |
Allen, RH; Beresford, SA; Brodkin, KI; Rajan, S; Stabler, SP; Wallace, JI | 1 |
Geisel, J; Herrmann, W | 1 |
Allen, RH; Baker, SD; Calvert, AH; Nelson, K; Niyikiza, C; Paoletti, P; Rusthoven, JJ; Seitz, DE; Stabler, SP; Walling, JM | 1 |
Allen, LH; Boy, E; Chew, F; Green, R; Miller, JW; Rodriguez, M; Rogers, LM | 1 |
Allen, LH; Boy, E; Green, R; Miller, JW; Rogers, LM; Sabel, JC | 1 |
Bates, CJ; Mansoor, MA; Mishra, G; Prentice, A; Schneede, J | 1 |
Allen, R; Bunn, PA; Calvert, AH; Hanauske, AR; Niyikiza, C; Paoletti, P; Rusthoven, JJ | 1 |
Bridge, PJ; Fung, E; Hyndman, ME; Manns, BJ; Parsons, HG; Scott-Douglas, NW; Snyder, FF | 1 |
Busch, M; Franke, S; Kientsch-Engel, R; Müller, A; Sommer, M; Stein, G | 1 |
Chin A Paw, MJ; De Groot, LC; de Jong, N; Dhonukshe-Rutten, RA; Hiddink, GJ; Lips, M; van Dusseldorp, M; van Staveren, WA | 1 |
Arnadottir, M; Hultberg, B | 1 |
Birks, J; Clarke, R; Evans, JG; Johnston, C; McPartlin, J; Nexo, E; Refsum, H; Schneede, J; Scott, JM; Sherliker, P; Ueland, PM | 1 |
Baumoehl, Y; Caspi, D; Elkayam, O; Habot, B; Leibovitz, A; Levartovsky, D; Litinsky, I; Paran, D; Segal, R; Sela, BA; Wigler, I | 1 |
Geisel, J; Herrmann, W; Obeid, R; Schorr, H; Zarzour, W | 1 |
Avşar, K; Cetin, M; Gök, M; Gültepe, M; Ozcan, O; Ozdemir, AS | 1 |
Balla, B; Brattström, L; Hebelka, H; Hultgren, M; Kågedal, B; Landtblom, AM; Leerbeck, K; Mattsson, E; Nilsson, H; Osterberg, A; Vrethem, M | 1 |
Geisel, J; Herrmann, W; Obeid, R; Schorr, H | 2 |
Hamilton, V; Juhasz-Pocsine, K; Luzzio, CC; Waclawik, AJ | 1 |
Barohn, RJ; Bryan, WW; Gronseth, GS; Herbelin, LL; Nations, SP; Saperstein, DS; Wolfe, GI | 1 |
Borch, K; Marcusson, J; Mårdh, E; Mårdh, S; Nägga, K; Rajani, R | 1 |
Hahn, A; Hermann, S; Wolters, M | 2 |
Benoist, JF; Bolgert, F; Demeret, S; Gervais, D; Ogier de Baulny, H; Pierrot-Deseilligny, C; Roze, E; Said, G; Zittoun, J | 1 |
Lewerin, C; Lindstedt, G; Matousek, M; Nilsson-Ehle, H; Steen, B | 1 |
Kjaerstad, SI; Schneede, J; Ueland, PM | 1 |
Markestad, T; Monsen, AL; Refsum, H; Ueland, PM | 1 |
Hvas, AM; Nexo, E | 2 |
Georg, T; Herrmann, M; Herrmann, W; Kindermann, W; Obeid, R; Scharhag, J; Schorr, H; Urhausen, A; Wilkinson, J | 1 |
Evans, LR; Freedman, M; Garcia, AA; Haron, Y; Roman, GC; Smith, MG | 1 |
Eckert, R; Herrmann, W; Obeid, R; Schorr, H | 1 |
Bjørke Monsen, AL; Markestad, T; Refsum, H; Ueland, PM; Vollset, SE | 1 |
Cole, DE; Delgado, DH; Evrovski, J; Keren, ES; Langman, LJ; Mamer, OA; Miner, SE; Miriuka, SG; Ross, HJ | 1 |
Albanes, D; Baer, DJ; Brown, ED; Campbell, WS; Clevidence, BA; Dorgan, JF; Gunter, EW; Hartman, TJ; Judd, JT; Laufer, EM; Taylor, PR | 1 |
Norman, EJ | 1 |
Allen, R; Anand, K; Boden-Albala, B; Lee, HS; Paik, MC; Sacco, RL; Stabler, S | 1 |
Solomon, LR | 5 |
Antonello, RM; Bava, A; Cattaruzza, T; Cazzato, G; Moretti, R; Torre, P | 1 |
Herrmann, W; Köhler, H; Kuhlmann, MK; Obeid, R | 1 |
Geisel, J; Herrmann, W; Hübner, U; Koch, I; Obeid, R; Retzke, U | 1 |
Herrmann, W; Kirsch, CM; Kuhlmann, M; Obeid, R | 1 |
Girard, CL; Matte, JJ | 1 |
Bjørke Monsen, AL; Riedel, B; Schneede, J; Ueland, PM | 1 |
Cole, DE; Ray, JG | 1 |
Hahn, A; Ströhle, A; Wolters, M | 1 |
Fowler, B; Herrmann, W; Kuhlmann, MK; Makowski, J; Obeid, R; Schorr, H | 1 |
Beaudet, AL; Bodamer, OA; Bottiglieri, T; O'Brien, WE; Sahoo, T; Scaglia, F; Stöckler-Ipsiroglu, S; Wagner, C | 1 |
Boxer, AL; Finley, R; Goldman, J; Johnston, K; Kramer, JH; Miller, BL | 1 |
Johansson, B; Lewerin, C; Matousek, M; Nilsson-Ehle, H; Steen, B; Steen, G | 1 |
Clarke, R; de Groot, LC; Eussen, SJ; Hoefnagels, WH; Schneede, J; Ueland, PM; van Staveren, WA | 1 |
Jacques, PF; Morris, MS; Selhub, J | 2 |
Herrmann, W; Jäger, M; Munz, W; Obeid, R; Schmidt, W | 1 |
Shojania, AM | 1 |
Schneede, J; Ueland, PM | 2 |
Fulton, AB; Hansen, RM; Marsden, DL; Tsina, EK | 1 |
Caudill, SP; Gunter, EW; Osterloh, J; Pfeiffer, CM; Sampson, EJ | 1 |
Arseth, O; Kvalheim, G; Ueland, PM; Windelberg, A | 1 |
Henriksen, TB; Møller, J; Møller, UK; Nexø, E; Ramlau-Hansen, CH | 1 |
Arning, E; Barbé, F; Bottiglieri, T; Franck, P; Montagne, P; Nicolas, JP; Serot, JM | 1 |
Herrmann, M; Herrmann, W; Kindermann, W; Obeid, R; Scharhag, J | 1 |
de Rooij, SE; Fischer, C; Hoekstra, JB; Huijmans, JG; Wiersinga, WJ | 1 |
Bor, MV; Lydeking-Olsen, E; Møller, J; Nexø, E | 1 |
Butler, C; Ellis, R; Goringe, A; Jenkins, C; McDowell, I; Vidal-Alaball, J; Worwood, M | 1 |
Campbell, CD; Ficicioglu, C; Ganesh, J | 1 |
Bergholt, T; Byg, KE; Eriksen, L; Hvas, AM; Milman, N | 2 |
Blom, HJ; Bloo, RJ; Clarke, R; de Groot, LC; Eussen, SJ; Hoefnagels, WH; Joosten, LW; Schneede, J; Ueland, PM; van Staveren, WA | 1 |
Herrmann, W; Hoever, J; Klockgether, T; Linnebank, M; Sturm, KU; Wellmer, J | 1 |
Hasegawa, Y; Jiang, Y; Qin, J; Song, J; Sun, F; Wu, X; Yamaguchi, S; Yang, Y; Zhang, Y | 1 |
Becker, G; Fassbender, K; Herrmann, W; Kasoha, M; Knapp, JP; Kostopoulos, P; Obeid, R | 1 |
Cravens, DD; Nashelsky, J; Oh, RC | 1 |
Lewerin, C; Ljungman, S; Nilsson-Ehle, H | 1 |
Irjala, K; Isoaho, R; Kivelä, SL; Koskinen, P; Loikas, S; Löppönen, M; Pelliniemi, TT | 1 |
Aarsetøy, H; Grundt, H; Mansoor, MA; Nilsen, DW; Reine, A; Valente, E | 1 |
Baer, DJ; Clevidence, BA; Ettinger, S; Hartman, TJ; Johnson, L; Mahabir, S; Taylor, PR | 1 |
Azzoli, CG; Dunne, M; Farmer, A; Ginsberg, MS; Gomez, J; Henry, R; Jones, J; Kris, MG; Krug, LM; Miller, VA; Pizzo, B; Sirotnak, FM; Steffen, R; Tyson, L; Venkatraman, E | 1 |
Allen, RH; Barbosa, PR; Braga, RC; Guerra-Shinohara, EM; Hirata, MH; Hirata, RD; Machado, AL; Sampaio-Neto, LF; Stabler, SP | 1 |
Aloe, L; Gammella, E; Mutti, E; Scalabrino, G; Stampachiacchere, B; Stampachiacchiere, B; Tacchini, L; Triaca, V; Veber, D | 1 |
Guo, F; Jia, Z; Wang, R; Zhang, W; Zhu, X | 1 |
Bahl, R; Bhan, MK; Bhandari, N; Gjessing, HK; Refsum, H; Schneede, J; Sommerfelt, H; Strand, TA; Taneja, S; Ueland, PM | 1 |
Blom, HJ; Heil, SG; Hogeveen, M; Kluijtmans, LA; Morava, E; van de Berg, GB; van Dijken, PJ | 1 |
Bhat, DS; Coyaji, KJ; Deshpande, SS; Deshpande, VU; Fall, CH; Fisher, DJ; Jackson, AA; Joglekar, CV; Joshi, N; Lubree, HG; Naik, SS; Rao, S; Refsum, H; Rege, SS; Yajnik, CS | 1 |
Alehan, F; Erol, I; Gümüs, A | 1 |
Clarke, SJ; Li, KM; Rivory, LP | 1 |
Dong, JH; Jiang, YW; Liu, P; Qin, J; Song, JQ; Wang, LF; Wu, XR; Yan, R; Yang, YL; Zhang, Y; Zhang, YH | 1 |
Bahl, R; Bhan, MK; Bhandari, N; Refsum, H; Schneede, J; Sommerfelt, H; Strand, TA; Taneja, S; Ueland, PM | 1 |
Birks, J; Clarke, R; Evans, JG; Molloy, A; Nexo, E; Schneede, J; Scott, J; Ueland, PM | 1 |
Agudo, A; Allen, N; Barricarte, A; Berglund, G; Bingham, S; Boeing, H; Boutron-Ruault, MC; Büchner, FL; Bueno-de-Mesquita, HB; Capella, G; Carneiro, F; Clavel-Chapelon, F; Del Giudice, G; Dorronsoro, M; Eussen, S; Ferrari, P; Fredriksen, A; Gjessing, HK; González, CA; Hallmans, G; Igland, J; Jenab, M; Kaaks, R; Key, TJ; Linseisen, J; Lund, E; Manjer, J; Martínez, C; Meyer, K; Navarro, C; Numans, ME; Overvad, K; Pala, V; Palli, D; Panico, S; Peeters, PH; Pera, G; Quirós, JR; Riboli, E; Sala, N; Slimani, N; Stenling, R; Tjønneland, A; Trichopoulou, A; Tumino, R; Ueland, PM; Vineis, P; Vollset, SE; Weikert, C | 1 |
Allen, RH; Barbosa, PR; Carvalho, FR; Guerra-Shinohara, EM; Hirata, MH; Hirata, RD; Luchessi, AD; Stabler, SP; Trentin, R | 1 |
Allen, RH; De Chicchis, AR; Johnson, MA; Park, S; Shea-Miller, K; Stabler, SP | 1 |
Blom, H; den Heijer, M; Hogeveen, M; Kluijtmans, L; van Beynum, I; van Rooij, A | 1 |
Quinlivan, EP | 1 |
Dong, JH; Hasegawa, Y; Liu, P; Qin, J; Sayami, S; Shi, CY; Song, JQ; Yamaguchi, S; Yan, R; Yang, YL; Zhang, Y | 1 |
Hempen, C; van der Sluijs Veer, G; Wanschers, H | 1 |
Husek, P; Simek, P; Zahradnícková, H | 1 |
Bjørke-Monsen, AL; Markestad, T; Saetran, H; Torsvik, I; Ueland, PM | 1 |
Hay, G; Johnston, C; Refsum, H; Trygg, K; Whitelaw, A | 2 |
Brouwer, IA; Clarke, R; Katan, MB; Verhoef, P; Winkels, RM | 1 |
Choumenkovitch, S; Dallal, G; Jacques, PF; Rogers, G; Selhub, J | 1 |
Brown, MS; Furtado, S; Suchowersky, O; Toth, C; Zochodne, D | 1 |
Driever, PH; Hennermann, JB; Massenkeil, G; Sturm, I; von Arnim-Baas, A | 1 |
Allen, RH; Carvalho, FR; Guerra-Shinohara, EM; Hirata, MH; Hirata, RD; Lopreato, FR; Robi, DL; Sampaio-Neto, LF; Stabler, SP | 1 |
Kanakkaparambil, R; Li, D; Sinclair, KD; Singh, R; Webb, R | 1 |
Hahn, A; Stettin, D; Ströhle, A; Waldmann, A | 1 |
Coskun, O; Inan, L; Kara, N; Saydam, G; Senes, M; Yucel, D | 1 |
Biselli, PM; Carvalho, VM; de Godoy, MF; Eberlin, MN; Goloni-Bertollo, EM; Guerzoni, AR; Haddad, R; Pavarino-Bertelli, EC; Vannucchi, H | 1 |
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43 review(s) available for homocysteine and methylmalonic acid
Article | Year |
---|---|
[Determination of homocysteine and methylmalonic acid in cobalamin deficiency. Diagnostic problem with a solution?].
Topics: Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12 Deficiency | 1991 |
Diagnosis of megaloblastic anemia.
Topics: Anemia, Megaloblastic; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12 Deficiency | 1991 |
How to diagnose cobalamin deficiency.
Topics: Gastrins; History, 19th Century; History, 20th Century; Homocysteine; Humans; Methylmalonic Acid; Pepsinogens; Schilling Test; Vitamin B 12; Vitamin B 12 Deficiency | 1994 |
[P-methylmalonate and P-homocysteine: metabolic markers of vitamin deficiencies. Background, validity and applications].
Topics: Amino Acids; Biomarkers; Blood Chemical Analysis; Evaluation Studies as Topic; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency; Vitamin B Deficiency | 1996 |
High prevalence of cobalamin deficiency in the elderly.
Topics: Aged; Hematologic Diseases; Homocysteine; Humans; Mental Disorders; Methylmalonic Acid; Nervous System Diseases; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Vitamin B12 replacement. To B12 or not to B12?
Topics: Family Practice; Homocysteine; Humans; Methylmalonic Acid; Prevalence; Research Design; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Vitamin B-12 deficiency in the elderly: current dilemmas.
Topics: Acyl Coenzyme A; Aged; Aged, 80 and over; Female; Homocysteine; Humans; Male; Methionine; Methylmalonic Acid; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Remethylation defects: guidelines for clinical diagnosis and treatment.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Betaine; Child, Preschool; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Practice Guidelines as Topic; Vitamin B 12 | 1998 |
Relevance of vitamins, homocysteine and other metabolites in neuropsychiatric disorders.
Topics: Central Nervous System Diseases; Citrates; Demyelinating Diseases; Folic Acid; Homocysteine; Humans; Mental Disorders; Methionine; Methylmalonic Acid; Vitamin B 12 | 1998 |
[Inherited disorders of cobalamin metabolism].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Biomarkers; Child, Preschool; Diagnosis, Differential; Homocysteine; Humans; Infant; Infant, Newborn; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Mutation; Prognosis; Vitamin B 12; Vitamin B 12 Deficiency | 1998 |
Laboratory diagnosis of vitamin B12 and folate deficiency: a guide for the primary care physician.
Topics: Antibodies; Clinical Laboratory Techniques; Clinical Trials as Topic; Decision Trees; Diagnosis, Differential; Erythrocytes; Folic Acid Deficiency; Hematologic Diseases; Homocysteine; Humans; Intrinsic Factor; Methylmalonic Acid; Nervous System Diseases; Parietal Cells, Gastric; Primary Health Care; Schilling Test; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
[Diagnosis of vitamin B12 deficiency: only apparently child's play].
Topics: Aging; Anemia, Pernicious; Blood Cell Count; Diagnosis, Differential; Folic Acid Deficiency; Gastritis, Atrophic; Gastroscopy; Homocysteine; Humans; Methylmalonic Acid; Schilling Test; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Cobalamin and folate evaluation: measurement of methylmalonic acid and homocysteine vs vitamin B(12) and folate.
Topics: Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
[Homocysteine and methylmalonic acid as markers of cobalamin/folate status. The association to neuropsychiatric symptoms in the elderly is explored].
Topics: Aged; Biomarkers; Cognition Disorders; Diagnosis, Differential; Folic Acid Deficiency; Geriatric Psychiatry; Homocysteine; Humans; Mental Disorders; Methylmalonic Acid; Reference Values; Vitamin B 12 Deficiency | 2000 |
Vegetarian lifestyle and monitoring of vitamin B-12 status.
Topics: Analysis of Variance; Diet, Vegetarian; Hemoglobins; Homocysteine; Humans; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Pemetrexed safety and dosing strategy.
Topics: Antimetabolites, Antineoplastic; Clinical Trials as Topic; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Homocysteine; Humans; Methylmalonic Acid; Neoplasms; Pemetrexed; Thymidylate Synthase; Vitamin B 12 | 2002 |
[Diagnosis of vitamin B12 deficiency--time for reflection].
Topics: Biomarkers; Homocysteine; Humans; Methylmalonic Acid; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
[Vitamin B12 in the Nordic countries. Deficiency, diagnosis, treatment in Sweden].
Topics: Biomarkers; Homocysteine; Humans; Methylmalonic Acid; Practice Patterns, Physicians'; Scandinavian and Nordic Countries; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Homocysteine and methylmalonic acid in diagnosis and risk assessment from infancy to adolescence.
Topics: Adolescent; Child; Child, Preschool; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Infant; Infant, Newborn; Methylmalonic Acid; Vitamin B 12 Deficiency | 2003 |
Vitamin B12 and folate depletion in cognition: a review.
Topics: Cognition; Cognition Disorders; Dementia; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
[Cobalamin--a critical nutritive element in old age].
Topics: Aged; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Novel and established markers of cobalamin deficiency: complementary or exclusive diagnostic strategies.
Topics: Biomarkers; Diagnosis, Differential; Homocysteine; Humans; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
[Diagnosis of vitamin B12 deficiency revised].
Topics: Homocysteine; Humans; Methylmalonic Acid; Predictive Value of Tests; Schilling Test; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Clinical inquiries. How do we evaluate a marginally low B12 level?
Topics: Evaluation Studies as Topic; Evidence-Based Medicine; Family Practice; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Prognosis; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
[Measurement of methylmalonic acid, homocysteine and methionine in cobalamin and folate deficiencies and homocysteinuria].
Topics: Amino Acid Metabolism, Inborn Errors; Biomarkers; Diagnosis, Differential; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Infant; Infant, Newborn; Methionine; Methylmalonic Acid; Vitamin B 12 Deficiency | 2008 |
The use of blood concentrations of vitamins and their respective functional indicators to define folate and vitamin B12 status.
Topics: Biomarkers; Erythrocytes; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Methylmalonic Acid; Nutrition Assessment; Nutritional Status; Reference Standards; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Studies of biomarker responses to intervention with vitamin B-12: a systematic review of randomized controlled trials.
Topics: Biomarkers; Dietary Supplements; Homocysteine; Humans; Methylmalonic Acid; Nutrition Assessment; Nutritional Status; Randomized Controlled Trials as Topic; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2009 |
Cobalamin C defect: natural history, pathophysiology, and treatment.
Topics: Age of Onset; Homocysteine; Humans; Methionine; Methylmalonic Acid; Models, Biological; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Biomarkers of cobalamin (vitamin B12) deficiency and its application.
Topics: Aging; Biomarkers; Cognition Disorders; Erythrocyte Indices; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Holotranscobalamin, a marker of vitamin B-12 status: analytical aspects and clinical utility.
Topics: Biomarkers; Circadian Rhythm; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Overview of a roundtable on NHANES monitoring of biomarkers of folate and vitamin B-12 status: measurement procedure issues.
Topics: Biomarkers; Chromatography, Liquid; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Nutrition Surveys; Tandem Mass Spectrometry; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Folate and vitamin B-12 biomarkers in NHANES: history of their measurement and use.
Topics: Bias; Biomarkers; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Nutrition Surveys; Public Policy; Vitamin B 12 | 2011 |
Biomarkers of cobalamin (vitamin B-12) status in the epidemiologic setting: a critical overview of context, applications, and performance characteristics of cobalamin, methylmalonic acid, and holotranscobalamin II.
Topics: Biomarkers; Homocysteine; Humans; Methylmalonic Acid; Public Health; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Biomarkers of vitamin B-12 status in NHANES: a roundtable summary.
Topics: Biomarkers; Cognition Disorders; Homocysteine; Humans; Methylmalonic Acid; Nutrition Surveys; Public Health; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Clinical practice. Vitamin B12 deficiency.
Topics: Administration, Oral; Anemia, Pernicious; Child; Child Nutrition Disorders; Diagnostic Errors; Female; Homocysteine; Humans; Infant; Infant Nutrition Disorders; Injections; Intestinal Absorption; Methylmalonic Acid; Middle Aged; Paresthesia; Practice Guidelines as Topic; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
[Advances in the clinical and laboratory studies on methylmalonic aciduria combined with homocysteinemia type cblC].
Topics: Adult; Age of Onset; Amino Acid Metabolism, Inborn Errors; Betaine; Carrier Proteins; Child; China; DNA Mutational Analysis; Gas Chromatography-Mass Spectrometry; Genotype; Homocysteine; Humans; Hydroxocobalamin; Hyperhomocysteinemia; Infant; Methylmalonic Acid; Mutation; Oxidoreductases; Vitamin B 12 | 2013 |
The role of the one-carbon cycle in the developmental origins of Type 2 diabetes and obesity.
Topics: Adiposity; Carbon Cycle; Diabetes Mellitus, Type 2; Environmental Exposure; Female; Fetal Development; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant, Newborn; Insulin Resistance; Male; Maternal Nutritional Physiological Phenomena; Methylmalonic Acid; Obesity; Pregnancy; Prenatal Exposure Delayed Effects; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Vitamin B12 deficiency.
Topics: Homocysteine; Humans; Hydroxocobalamin; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2014 |
Vitamin B
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Child; Child, Preschool; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Prevalence; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2017 |
Association of
Topics: Adult; Aged; Alleles; Alzheimer Disease; Carbon; Child; Congenital Abnormalities; Female; Genotype; Homocysteine; Humans; Male; Methylmalonic Acid; Neoplasms; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; White People | 2017 |
Atypical hemolytic uremic syndrome induced by CblC subtype of methylmalonic academia: A case report and literature review.
Topics: Amino Acid Metabolism, Inborn Errors; Atypical Hemolytic Uremic Syndrome; Carrier Proteins; Child, Preschool; Female; Homocysteine; Humans; Kidney; Methylmalonic Acid; Mutation; Oxidoreductases; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2017 |
Proton Pump Inhibitors, H2-Receptor Antagonists, Metformin, and Vitamin B-12 Deficiency: Clinical Implications.
Topics: Histamine H2 Antagonists; Homocysteine; Humans; Metformin; Methylmalonic Acid; Nutritional Status; Proton Pump Inhibitors; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Review article: Clinical manifestations and outcomes of chronic nitrous oxide misuse: A systematic review.
Topics: Homocysteine; Humans; Methylmalonic Acid; Nitrous Oxide; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
64 trial(s) available for homocysteine and methylmalonic acid
Article | Year |
---|---|
Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations.
Topics: Aged; Aged, 80 and over; Avitaminosis; Citrates; Cystathionine; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Injections, Intramuscular; Male; Methylmalonic Acid; Placebos; Prospective Studies; Pyridoxine; Vitamin B 12; Vitamin B 12 Deficiency | 1995 |
Methylmalonic acid and homocysteine in plasma as indicators of functional cobalamin deficiency in infants on macrobiotic diets.
Topics: Diet, Macrobiotic; Female; Homocysteine; Humans; Infant; Male; Methylmalonic Acid; Reference Values; Vitamin B 12 Deficiency | 1994 |
Metformin increases total serum homocysteine levels in non-diabetic male patients with coronary heart disease.
Topics: Adult; Coronary Disease; Cysteine; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Methylmalonic Acid; Middle Aged; Vitamin B 12 | 1997 |
Effective treatment of cobalamin deficiency with oral cobalamin.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Female; Folic Acid; Hematocrit; Homocysteine; Humans; Injections, Intramuscular; Male; Methylmalonic Acid; Middle Aged; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 1998 |
Pathological changes in cobalt-supplemented and non-supplemented twin lambs in relation to blood concentrations of methylmalonic acid and homocysteine.
Topics: Animals; Brain; Brain Diseases; Cobalt; Copper; Diet; Female; Hepatitis, Chronic; Homocysteine; Litter Size; Liver; Male; Methylmalonic Acid; Sheep; Sheep Diseases; Twins; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Elevated serum levels of methylmalonic acid and homocysteine in elderly people. A population-based intervention study.
Topics: Administration, Oral; Aged; Female; Folic Acid; Hematinics; Homocysteine; Humans; Injections, Intramuscular; Male; Methylmalonic Acid; Treatment Outcome; Vitamin B 12 | 1999 |
Total homocysteine is associated with nephropathy in non-insulin-dependent diabetes mellitus.
Topics: Adult; Aged; Albuminuria; Cystathionine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Kidney Function Tests; Male; Methylmalonic Acid; Middle Aged; Regression Analysis; Vitamins | 1999 |
Elevated serum levels of methylmalonic acid and homocysteine in elderly people. A population-based intervention study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Drug Therapy, Combination; Female; Folic Acid; Hematinics; Homocysteine; Humans; Injections, Intramuscular; Male; Methylmalonic Acid; Population Surveillance; Treatment Outcome; Vitamin B 12 | 1999 |
The plasma homocysteine concentration is better than that of serum methylmalonic acid as a marker for sociopsychological performance in a psychogeriatric population.
Topics: Aged; Aged, 80 and over; Dementia; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Methylmalonic Acid; Psychiatric Status Rating Scales; Regression Analysis; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Nutrient-dense foods and exercise in frail elderly: effects on B vitamins, homocysteine, methylmalonic acid, and neuropsychological functioning.
Topics: Aged; Aged, 80 and over; Cohort Studies; Cross-Sectional Studies; Dietary Supplements; Exercise; Female; Food, Fortified; Frail Elderly; Homocysteine; Humans; Male; Methylmalonic Acid; Nervous System Diseases; Nervous System Physiological Phenomena; Netherlands; Neuropsychological Tests; Nutrition Policy; Nutritional Status; Nutritive Value; Socialization; Surveys and Questionnaires; Vitamin B Complex | 2001 |
Parenteral vitamin B12 reduces hyperhomocysteinemia in end-stage renal disease.
Topics: Cysteine; Homocysteine; Humans; Hyperhomocysteinemia; Injections, Subcutaneous; Kidney Failure, Chronic; Methylmalonic Acid; Renal Dialysis; Vitamin B 12 | 2001 |
Vitamin B12 treatment normalizes metabolic markers but has limited clinical effect: a randomized placebo-controlled study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Neurologic Examination; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Determinants of cobalamin status in newborns.
Topics: Adult; Biomarkers; Female; Homocysteine; Humans; Infant, Newborn; Logistic Models; Maternal-Fetal Exchange; Methylmalonic Acid; Parity; Pregnancy; Reference Values; Vitamin B 12 | 2001 |
Decrease of elevated N,N-dimethylglycine and N-methylglycine in human immunodeficiency virus infection during short-term highly active antiretroviral therapy.
Topics: Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Antigens, CD; Antiretroviral Therapy, Highly Active; Biomarkers; Cystathionine; Cysteine; Fasting; Female; Folic Acid; HIV Infections; HIV-1; Homocysteine; Humans; Male; Methionine; Methylmalonic Acid; Middle Aged; Multivariate Analysis; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Sarcosine; Vitamin B 6 | 2001 |
The effect of folic acid supplementation on plasma homocysteine in an elderly population.
Topics: Aged; Cardiovascular Diseases; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Hematinics; Homocysteine; Humans; Linear Models; Male; Methylmalonic Acid | 2002 |
Hydroxocobalamin reduces hyperhomocysteinemia in end-stage renal disease.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Hyperhomocysteinemia; Injections, Subcutaneous; Kidney Failure, Chronic; Male; Methylmalonic Acid; Middle Aged; Prospective Studies; Renal Dialysis; Treatment Outcome; Vitamin B 12 | 2002 |
Response of elevated methylmalonic acid to three dose levels of oral cobalamin in older adults.
Topics: Administration, Oral; Age Factors; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Pilot Projects; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Vitamin B12 decreases, but does not normalize, homocysteine and methylmalonic acid in end-stage renal disease: a link with glycine metabolism and possible explanation of hyperhomocysteinemia in end-stage renal disease.
Topics: Cysteine; Genotype; Glycine; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Threonine; Vitamin B 12 | 2003 |
The effect of vitamin B12 on total plasma homocysteine concentration in folate-replete hemodialysis patients.
Topics: Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Middle Aged; Renal Dialysis; Statistics, Nonparametric; Treatment Outcome; Vitamin B 12 | 2003 |
Neuropsychiatric disturbances in presumed late-onset cobalamin C disease.
Topics: Adolescent; Adult; Brain; Cobamides; Female; Fibroblasts; Homocysteine; Humans; Mental Disorders; Metabolism, Inborn Errors; Methylmalonic Acid; Nervous System Diseases; Sural Nerve; Vitamin B 12 | 2003 |
Reduction of plasma homocysteine and serum methylmalonate concentrations in apparently healthy elderly subjects after treatment with folic acid, vitamin B12 and vitamin B6: a randomised trial.
Topics: Aged; Aged, 80 and over; Double-Blind Method; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Methylmalonic Acid; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2003 |
Effects of folic acid fortification and multivitamin therapy on homocysteine and vitamin B(12) status in cardiac transplant recipients.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Canada; Cohort Studies; Dietary Supplements; Female; Ferredoxin-NADP Reductase; Folic Acid; Food, Fortified; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamins | 2004 |
Effects of moderate alcohol consumption on folate and vitamin B(12) status in postmenopausal women.
Topics: Aged; Alcohol Drinking; Cross-Over Studies; DNA Methylation; Dose-Response Relationship, Drug; Ethanol; Female; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Nutritional Status; Postmenopause; Vitamin B 12 | 2004 |
Effect of multivitamin supplementation on the homocysteine and methylmalonic acid blood concentrations in women over the age of 60 years.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Geriatric Assessment; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Minerals; Risk Assessment; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamins | 2005 |
Holotranscobalamin--a first choice assay for diagnosing early vitamin B deficiency?
Topics: Adult; Aged; Aged, 80 and over; Anemia; Biomarkers; Creatinine; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Prognosis; Thyrotropin; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Significant correlations of plasma homocysteine and serum methylmalonic acid with movement and cognitive performance in elderly subjects but no improvement from short-term vitamin therapy: a placebo-controlled randomized study.
Topics: Aged; Cognition; Double-Blind Method; Female; Folic Acid; Folic Acid Deficiency; Geriatrics; Homocysteine; Humans; Locomotion; Male; Methylmalonic Acid; Psychomotor Performance; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency; Vitamin B Complex | 2005 |
Oral cyanocobalamin supplementation in older people with vitamin B12 deficiency: a dose-finding trial.
Topics: Administration, Oral; Aged; Aged, 80 and over; Biomarkers; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Homocysteine; Humans; Male; Methylmalonic Acid; Radioimmunoassay; Retrospective Studies; Transcobalamins; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Biochemical indexes of the B vitamins in cord serum are predicted by maternal B vitamin status.
Topics: Adult; Female; Fetal Blood; Gestational Age; Homocysteine; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Methylmalonic Acid; Nutritional Status; Predictive Value of Tests; Pregnancy; Vitamin B Complex | 2005 |
The limited value of methylmalonic acid, homocysteine and holotranscobalamin in the diagnosis of early B12 deficiency.
Topics: Diagnosis; Homocysteine; Humans; Methylmalonic Acid; Sensitivity and Specificity; Transcobalamins; Vitamin B 12 Deficiency | 2006 |
Effect of oral vitamin B-12 with or without folic acid on cognitive function in older people with mild vitamin B-12 deficiency: a randomized, placebo-controlled trial.
Topics: Administration, Oral; Aged; Aged, 80 and over; Cognition; Cognition Disorders; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Male; Memory; Methylmalonic Acid; Psychomotor Performance; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Measures of adiposity and body fat distribution in relation to serum folate levels in postmenopausal women in a feeding study.
Topics: Absorptiometry, Photon; Adipose Tissue; Adiposity; Aged; Alcohol Drinking; Body Composition; Body Mass Index; Cross-Over Studies; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Multivariate Analysis; Obesity; Overweight; Postmenopause; Vitamin B 12 | 2008 |
A phase 1 study of pralatrexate in combination with paclitaxel or docetaxel in patients with advanced solid tumors.
Topics: Adult; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Dietary Supplements; Docetaxel; Female; Folic Acid Antagonists; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Neoplasms; Paclitaxel; Taxoids; Vitamins | 2007 |
Pemetrexed pharmacokinetics and pharmacodynamics in a phase I/II study of doublet chemotherapy with vinorelbine: implications for further optimisation of pemetrexed schedules.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma, Non-Small-Cell Lung; Deoxyuridine; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Glutamates; Guanine; Homocysteine; Humans; Lung Neoplasms; Male; Methylmalonic Acid; Middle Aged; Pemetrexed; Thymidine; Thymidylate Synthase; Vinblastine; Vinorelbine; Vitamin B 12 | 2007 |
[Clinical studies on fifty-seven Chinese patients with combined methylmalonic aciduria and homocysteinemia].
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Anemia; Carnitine; Child; Child, Preschool; China; Female; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Metabolic Diseases; Methylmalonic Acid; Urologic Diseases; Vitamin B 12; Vitamin B Complex; Young Adult | 2007 |
Cobalamin and folate status in infants and young children in a low-to-middle income community in India.
Topics: Child, Preschool; Double-Blind Method; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; India; Infant; Male; Methylmalonic Acid; Nutritional Status; Socioeconomic Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Age-related hearing loss, methylmalonic acid, and vitamin B12 status in older adults.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Cohort Studies; Creatinine; Dietary Supplements; Dose-Response Relationship, Drug; Female; Geriatric Assessment; Hearing Loss; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Nutritional Status; Socioeconomic Factors; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2006 |
Common metabolic profile in infants indicating impaired cobalamin status responds to cobalamin supplementation.
Topics: Breast Feeding; Dietary Supplements; Folic Acid; Homocysteine; Humans; Infant; Linear Models; Methylmalonic Acid; Vitamin B 12 | 2008 |
Bread cofortified with folic acid and vitamin B-12 improves the folate and vitamin B-12 status of healthy older people: a randomized controlled trial.
Topics: Aged; Aging; Bread; Double-Blind Method; Erythrocytes; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Neural Tube Defects; Nutritional Requirements; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Oral vitamin B12 for patients suspected of subtle cobalamin deficiency: a multicentre pragmatic randomised controlled trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Blood Specimen Collection; Dietary Supplements; Female; Follow-Up Studies; Homocysteine; Humans; Least-Squares Analysis; Male; Methylmalonic Acid; Middle Aged; Patient Compliance; Switzerland; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Young Adult | 2011 |
Cobalamin status modifies the effect of zinc supplementation on the incidence of prolonged diarrhea in 6- to 30-month-old north Indian children.
Topics: Child, Preschool; Diarrhea; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Incidence; India; Infant; Male; Methylmalonic Acid; Vitamin B 12; Zinc | 2011 |
The vitamin B12 absorption test, CobaSorb, identifies patients not requiring vitamin B12 injection therapy.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Biomarkers; Blood Chemical Analysis; Female; Hemoglobins; Homocysteine; Humans; Injections; Intestinal Absorption; Male; Methylmalonic Acid; Middle Aged; Prospective Studies; Reference Values; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Vitamin B-12 supplementation of rural Mexican women changes biochemical vitamin B-12 status indicators but does not affect hematology or a bone turnover marker.
Topics: Adult; Alkaline Phosphatase; Bone Remodeling; C-Reactive Protein; Dietary Supplements; Female; Ferritins; Folic Acid; Homocysteine; Humans; Logistic Models; Methylmalonic Acid; Mexico; Middle Aged; Nutritional Status; Rural Population; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Young Adult | 2012 |
Cobalamin and folate status predicts mental development scores in North Indian children 12-18 mo of age.
Topics: Biomarkers; Child Development; Cognition Disorders; Cohort Studies; Developmental Disabilities; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; India; Infant; Male; Methylmalonic Acid; Neurogenesis; Nutritional Status; Prevalence; Psychomotor Performance; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Cobalamin supplementation improves motor development and regurgitations in infants: results from a randomized intervention study.
Topics: Biomarkers; Child Development; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hydroxocobalamin; Infant; Injections, Intramuscular; Linear Models; Male; Methylmalonic Acid; Surveys and Questionnaires; Vitamin B 12 Deficiency; Vomiting | 2013 |
Three-month B vitamin supplementation in pre-school children affects folate status and homocysteine, but not cognitive performance.
Topics: Biomarkers; Calcium, Dietary; Child; Child, Preschool; Cognition; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Germany; Homocysteine; Humans; Male; Memory, Short-Term; Methylmalonic Acid; Vitamin B 12; Vitamin B Complex | 2014 |
B-vitamin levels and genetics of hyperhomocysteinemia are not associated with arterial stiffness.
Topics: Aged; Aged, 80 and over; Blood Pressure; Body Mass Index; Creatinine; Cross-Sectional Studies; Double-Blind Method; Female; Folic Acid; Genotyping Techniques; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Methylmalonic Acid; Multivariate Analysis; Pulse Wave Analysis; Risk Factors; Vascular Stiffness; Vitamin B 12; Vitamin B Complex | 2014 |
Vitamin B12 supplementation during pregnancy and postpartum improves B12 status of both mothers and infants but vaccine response in mothers only: a randomized clinical trial in Bangladesh.
Topics: Adolescent; Adult; Bangladesh; Biomarkers; C-Reactive Protein; Dietary Supplements; Dose-Response Relationship, Drug; Female; Ferritins; Folic Acid; Hemoglobins; Homocysteine; Humans; Immunoglobulin A; Infant; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Lactation; Maternal Nutritional Physiological Phenomena; Methylmalonic Acid; Milk, Human; Orosomucoid; Postpartum Period; Pregnancy; Receptors, Transferrin; Vitamin B 12; Young Adult | 2016 |
Vitamin B-12 Status Differs among Pregnant, Lactating, and Control Women with Equivalent Nutrient Intakes.
Topics: Adult; Biomarkers; Breast Feeding; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Energy Intake; Female; Healthy Volunteers; Homocysteine; Humans; Lactation; Methylmalonic Acid; Micronutrients; Postpartum Period; Pregnancy; Recommended Dietary Allowances; Vitamin B 12; Young Adult | 2015 |
Vitamin B-12 treatment of asymptomatic, deficient, elderly Chileans improves conductivity in myelinated peripheral nerves, but high serum folate impairs vitamin B-12 status response assessed by the combined indicator of vitamin B-12 status.
Topics: Aged; Chile; Dietary Supplements; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methylmalonic Acid; Nerve Fibers, Myelinated; Neural Conduction; Nutritional Status; Peripheral Nerves; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2016 |
Motor development related to duration of exclusive breastfeeding, B vitamin status and B12 supplementation in infants with a birth weight between 2000-3000 g, results from a randomized intervention trial.
Topics: Breast Feeding; Child Development; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Infant; Infant, Low Birth Weight; Male; Methylmalonic Acid; Motor Skills; Pyridoxal Phosphate; Riboflavin; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2015 |
Reduced folate and serum vitamin metabolites in patients with rectal carcinoma: an open-label feasibility study of pemetrexed with folic acid and vitamin B12 supplementation.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cystathionine; Feasibility Studies; Female; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Intestinal Mucosa; Male; Methylmalonic Acid; Middle Aged; Neoadjuvant Therapy; Pemetrexed; Rectal Neoplasms; Rectum; Vitamin B 12 | 2016 |
Methylmalonic acid and neutrophil morphometric index in laboratory diagnosis of cobalamin deficiency without macrocytosis.
Topics: Aged; Cell Nucleus; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Neutrophils; Vitamin B 12 Deficiency | 2016 |
A randomized placebo controlled trial of vitamin B
Topics: Aged; Cholesterol; Cognitive Dysfunction; Creatinine; Diabetes Mellitus; Dietary Supplements; Female; Follow-Up Studies; Homocysteine; Humans; Male; Methylmalonic Acid; Neuropsychological Tests; Socioeconomic Factors; Triglycerides; Vitamin B 12 | 2017 |
Whey protein isolate improves vitamin B
Topics: Aged; Australia; Cross-Over Studies; Diet; Dietary Supplements; DNA Damage; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Nutrition Assessment; Vitamin B 12; Vitamin B 12 Deficiency; Whey Proteins | 2017 |
Folate and Vitamin B
Topics: Aged; Biomarkers; Body Mass Index; Brain; Cross-Sectional Studies; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Linear Models; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Nutritional Status; Organ Size; Tandem Mass Spectrometry; Transcobalamins; Vitamin B 12 | 2016 |
Effects of metformin versus placebo on vitamin B12 metabolism in non-diabetic breast cancer patients in CCTG MA.32.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Female; Homocysteine; Humans; Metformin; Methylmalonic Acid; Middle Aged; Treatment Outcome; Vitamin B 12 | 2017 |
Cobalamin and Folate Status among Breastfed Infants in Bhaktapur, Nepal.
Topics: Biomarkers; Breast Feeding; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant; Infant Nutritional Physiological Phenomena; Male; Methylmalonic Acid; Nepal; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
The Effect of Whey and Soy Protein Isolates on Cognitive Function in Older Australians with Low Vitamin B
Topics: Aged; Australia; Cognition; Cross-Over Studies; Female; Folic Acid; Homocysteine; Humans; Male; Memory; Methylmalonic Acid; Middle Aged; Nutritional Status; Reaction Time; Sex Factors; Soybean Proteins; Vitamin B 12; Vitamin B 12 Deficiency; Whey Proteins | 2018 |
Effects of oral versus parenteral cobalamin supplementation on methylmalonic acid and homocysteine concentrations in dogs with chronic enteropathies and low cobalamin concentrations.
Topics: Administration, Oral; Animals; Dietary Supplements; Dog Diseases; Dogs; Female; Homocysteine; Infusions, Parenteral; Intestinal Diseases; Male; Methylmalonic Acid; Prospective Studies; Random Allocation; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Maternal choline supplementation alters vitamin B-12 status in human and murine pregnancy.
Topics: Adult; Animals; Betaine-Homocysteine S-Methyltransferase; Choline; Choline Dehydrogenase; Dietary Supplements; Female; Gene Expression Regulation; Homeodomain Proteins; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methylmalonic Acid; Mice, Mutant Strains; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Trimester, Third; Transcription Factors; Vitamin B 12; Young Adult | 2019 |
Vitamin B12 Status Upon Short-Term Intervention with a Vegan Diet-A Randomized Controlled Trial in Healthy Participants.
Topics: Adult; Biomarkers; Cardiovascular Diseases; Cholesterol; Diet, Vegan; Fatty Acids; Female; Healthy Volunteers; Homocysteine; Humans; Inflammation; Male; Methylmalonic Acid; Micronutrients; Nutritional Status; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Infantile Tremor Syndrome or a Neurocutaneous Infantile B12 Deficiency (NIB) Syndrome?
Topics: Adolescent; Adult; Biomarkers; Child; Child, Preschool; Erythrocyte Indices; Female; Folic Acid; Homocysteine; Humans; India; Male; Malnutrition; Methylmalonic Acid; Mothers; Prospective Studies; Tremor; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2020 |
Cobalamin and folate status in women during early pregnancy in Bhaktapur, Nepal.
Topics: Female; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Nepal; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
Plasma Methylmalonic Acid Concentration in Folic Acid-Supplemented Depressed Patients with Low or Marginal Vitamin B-12: A Randomized Trial.
Topics: Aged; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Vitamin B 12; Vitamins | 2021 |
332 other study(ies) available for homocysteine and methylmalonic acid
Article | Year |
---|---|
Prevalence of vitamin B12 deficiency among geriatric outpatients.
Topics: Aged; Aged, 80 and over; Female; Gastritis, Atrophic; Homocysteine; Humans; Male; Methylmalonic Acid; New York; Outpatients; Peripheral Nervous System Diseases; Prevalence; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 1992 |
High prevalence of cobalamin deficiency in elderly outpatients.
Topics: Aged; Aged, 80 and over; Ambulatory Care; Colorado; Female; Homocysteine; Humans; Male; Mass Screening; Methylmalonic Acid; Neurologic Examination; Neuropsychological Tests; Prevalence; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 1992 |
Homocystinuria, arteriosclerosis, methylmalonic aciduria, and methyltransferase deficiency: a key case revisited.
Topics: Arteriosclerosis; Homocysteine; Homocystinuria; Humans; Infant; Male; Methylmalonic Acid; Methyltransferases | 1992 |
Inhibition of cobalamin-dependent enzymes by cobalamin analogues in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Folic Acid; Homocysteine; Male; Methionine; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Nitrous Oxide; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Succinates; Succinic Acid; Vitamin B 12 | 1991 |
Maternal vegan diet causing a serious infantile neurological disorder due to vitamin B12 deficiency.
Topics: Adult; Breast Feeding; Diet, Vegetarian; Female; Homocysteine; Humans; Infant; Methionine; Methylmalonic Acid; Milk, Human; Nervous System Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 1991 |
Diagnosis of cobalamin deficiency I: usefulness of serum methylmalonic acid and total homocysteine concentrations.
Topics: Adolescent; Adult; Aged; Female; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Reference Values; Vitamin B 12 Deficiency | 1990 |
Diagnosis of cobalamin deficiency: II. Relative sensitivities of serum cobalamin, methylmalonic acid, and total homocysteine concentrations.
Topics: Adult; Aged; Celiac Disease; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Intestines; Male; Methylmalonic Acid; Middle Aged; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 1990 |
Clinical spectrum and diagnosis of cobalamin deficiency.
Topics: Bilirubin; Female; Folic Acid; Gastrins; Hematocrit; Homocysteine; Humans; L-Lactate Dehydrogenase; Male; Methylmalonic Acid; Prospective Studies; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 1990 |
Biochemical evidence of asymptomatic vitamin B12 deficiency in children after ileal resection for necrotizing enterocolitis.
Topics: Child; Child, Preschool; Enterocolitis, Pseudomembranous; Homocysteine; Humans; Ileum; Methylmalonic Acid; Vitamin B 12 Deficiency | 1989 |
Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis.
Topics: Adolescent; Adult; Aged; Anemia; Anemia, Megaloblastic; Ataxia; Erythrocyte Indices; Erythrocytes; Female; Hematocrit; Homocysteine; Humans; Hypesthesia; Iron; Male; Methylmalonic Acid; Middle Aged; Nervous System Diseases; Neurocognitive Disorders; Paresthesia; Vitamin B 12; Vitamin B 12 Deficiency | 1988 |
Cisplatin neurotoxicity: failure to demonstrate vitamin B12 inactivation.
Topics: Analysis of Variance; Circadian Rhythm; Cisplatin; Cobamides; Female; Homocysteine; Humans; Infusions, Parenteral; Methylmalonic Acid; Ovarian Neoplasms; Urinary Bladder Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 1985 |
Congenital methylmalonic aciduria--homocystinuria with megaloblastic anemia: observations on response to hydroxocobalamin and on the effect of homocysteine and methionine on the deoxyuridine suppression test.
Topics: Anemia, Megaloblastic; Deoxyuridine; DNA; Female; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Malonates; Methionine; Methylmalonic Acid; Myoclonus; Thymidine | 1980 |
Biochemical indices of vitamin B12 nutrition in pregnant patients with subnormal serum vitamin B12 levels.
Topics: Female; Homocysteine; Humans; Methylmalonic Acid; Nutritional Status; Pregnancy; Pregnancy Complications; Vitamin B 12 Deficiency | 1995 |
Homocysteine metabolism in pregnancies complicated by neural-tube defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Analysis of Variance; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methylation; Methylmalonic Acid; Neural Tube Defects; Pregnancy; Vitamin B 12 | 1995 |
Neuropathic bladder in setting of severe vitamin B12 deficiency: a case report.
Topics: Aged; Female; Homocysteine; Humans; Methylmalonic Acid; Movement Disorders; Sensation Disorders; Urinary Bladder, Neurogenic; Vitamin B 12 Deficiency | 1995 |
Evidence that homocysteine is an independent risk factor for atherosclerosis in hyperlipidemic patients.
Topics: Aged; Analysis of Variance; Arteriosclerosis; Coronary Disease; Cystathionine; Folic Acid; Homocysteine; Humans; Hyperlipidemias; Methylmalonic Acid; Middle Aged; Pyridoxine; Risk Factors | 1995 |
Vitamin B12 deficiency is the primary cause of megaloblastic anaemia in Zimbabwe.
Topics: Anemia, Megaloblastic; Anemia, Pernicious; Erythrocyte Indices; Female; Folic Acid; Folic Acid Deficiency; Gastrins; Hemoglobins; Homocysteine; Humans; Methylmalonic Acid; Nervous System Diseases; Neutrophils; Vitamin B 12 Deficiency; Zimbabwe | 1994 |
Guidelines on the investigation and diagnosis of cobalamin and folate deficiencies. A publication of the British Committee for Standards in Haematology. BCSH General Haematology Test Force.
Topics: Blood Cell Count; Bone Marrow Examination; Deoxyuridine; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12 Deficiency | 1994 |
Serum cobalamin deficiency is uncommon in multiple sclerosis.
Topics: Adult; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Multiple Sclerosis; Muscular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 1994 |
Screening for vitamin B12 deficiency in psychiatric patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Homocysteine; Humans; Male; Mental Disorders; Methylmalonic Acid; Middle Aged; Vitamin B 12 Deficiency | 1994 |
Prevalence of cobalamin deficiency in the Framingham elderly population.
Topics: Adult; Aged; Aged, 80 and over; Aging; Cohort Studies; Female; Folic Acid Deficiency; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Intrinsic Factor; Male; Massachusetts; Methylmalonic Acid; Middle Aged; Prevalence; Radioimmunoassay; Reference Values; Surveys and Questionnaires; Vitamin B 12 Deficiency | 1994 |
Identification and perturbation of mutant human fibroblasts based on measurements of methylmalonic acid and total homocysteine in the culture media.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line; Culture Media; Fibroblasts; Homocysteine; Humans; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Mutation; Propionates; Vitamin B 12 | 1993 |
Sensitivity of serum methylmalonic acid and total homocysteine determinations for diagnosing cobalamin and folate deficiencies.
Topics: Female; Folic Acid Deficiency; Homocysteine; Humans; Male; Methylmalonic Acid; Predictive Value of Tests; Sensitivity and Specificity; Vitamin B 12 Deficiency | 1994 |
Cobalamin absorption and serum homocysteine and methylmalonic acid in elderly subjects with low serum cobalamin.
Topics: Aged; Aged, 80 and over; Diagnosis, Differential; Female; Homocysteine; Humans; Intestinal Absorption; Malabsorption Syndromes; Male; Methylmalonic Acid; Prospective Studies; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 1993 |
Kinetics of total plasma homocysteine in subjects with hyperhomocysteinemia due to folate or cobalamin deficiency.
Topics: Adolescent; Adult; Aged; Female; Folic Acid; Folic Acid Deficiency; Half-Life; Hematinics; Homocysteine; Humans; Kinetics; Male; Methionine; Methylmalonic Acid; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Elevated methylmalonic acid and total homocysteine levels show high prevalence of vitamin B12 deficiency after gastric surgery.
Topics: Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Postoperative Complications; Stomach; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Age- and gender-specific reference intervals for total homocysteine and methylmalonic acid in plasma before and after vitamin supplementation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Reference Values; Sex Characteristics; Vitamin B 12; Vitamins | 1996 |
In vitro and in vivo inactivation of transcobalamin II receptor by its antiserum.
Topics: Animals; Antibodies; Cell Line; Cell Membrane; Cobalt Radioisotopes; Female; Homocysteine; Humans; Intestinal Mucosa; Kidney; Kinetics; Liver; Macromolecular Substances; Methylmalonic Acid; Placenta; Pregnancy; Rabbits; Radioligand Assay; Receptors, Cell Surface; Reference Values; Staphylococcal Protein A; Transcobalamins; Tumor Cells, Cultured | 1996 |
The use of homocysteine and other metabolites in the specific diagnosis of vitamin B-12 deficiency.
Topics: Adolescent; Adult; Aged; Female; Folic Acid Deficiency; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Vitamin B 12 Deficiency | 1996 |
Crohn's disease and vitamin B12 metabolism.
Topics: Adult; Crohn Disease; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Transcobalamins; Vitamin B 12 | 1996 |
Vitamin supplementation and other variables affecting serum homocysteine and methylmalonic acid concentrations in elderly men and women.
Topics: Aged; Aged, 80 and over; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Linear Models; Male; Methylmalonic Acid; Patient Selection; Prospective Studies; Vitamin B 12 Deficiency | 1996 |
Vitamin B12 deficiency after gastric surgery: its early detection.
Topics: Homocysteine; Humans; Methylmalonic Acid; Peptic Ulcer; Postoperative Complications; Stomach; Vitamin B 12 Deficiency | 1996 |
Cobalamin and folate deficiencies.
Topics: Biomarkers; Chemistry, Clinical; Folic Acid; Folic Acid Deficiency; Hematology; Homocysteine; Humans; Methylmalonic Acid; Practice Guidelines as Topic; Predictive Value of Tests; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Are different reference intervals for methylmalonic acid and total homocysteine necessary in elderly people?
Topics: Adult; Aged; Aged, 80 and over; Aging; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Nutritional Status; Reference Values; Vitamin B 12 | 1996 |
[Homocysteine and methylmalonic acid. New tests--for what benefit?].
Topics: Amino Acids; Evaluation Studies as Topic; Homocysteine; Humans; Mass Screening; Methylmalonic Acid; Vitamin B 12 Deficiency | 1996 |
Hormone replacement therapy and cobalamin status in elderly women.
Topics: Aged; Aging; Cohort Studies; Estrogen Replacement Therapy; Female; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12 | 1996 |
Alcoholic cirrhosis and cobalamin metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Biomarkers; Biopsy, Needle; Chronic Disease; Female; Follow-Up Studies; Homocysteine; Humans; Liver Cirrhosis, Alcoholic; Male; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Plasma methylmalonic acid in relation to serum cobalamin and plasma homocysteine in a psychogeriatric population and the effect of cobalamin treatment.
Topics: Aged; Biomarkers; Case-Control Studies; Drug Monitoring; Female; Geriatric Psychiatry; Homocysteine; Humans; Male; Mental Disorders; Methylmalonic Acid; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Is metabolic evidence for vitamin B-12 and folate deficiency more frequent in elderly patients with Alzheimer's disease?
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Female; Folic Acid Deficiency; Homocysteine; Hospitalization; Humans; Male; Methylmalonic Acid; Reference Values; Vitamin B 12 Deficiency | 1997 |
Enhanced levels of biochemical markers for cobalamin deficiency in totally gastrectomized rats: uncoupling of the enhancement from the severity of spongy vacuolation in spinal cord.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Pernicious; Animals; Bacteria, Anaerobic; Citrates; Cystathionine; Disease Models, Animal; Erythromycin; Gastrectomy; Homocysteine; Humans; Intestines; Lincomycin; Male; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Postgastrectomy Syndromes; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Diseases; Vacuoles; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Home parenteral nutrition and vitamin B12 status.
Topics: Adult; Aged; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Nutritional Status; Parenteral Nutrition, Home; Reference Values; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Diagnosis of cobalamin deficiency: the old and the new.
Topics: Erythrocyte Volume; Hematologic Tests; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
[Megaloblastic anemia: rapid and economical study].
Topics: Adolescent; Adult; Algorithms; Anemia, Megaloblastic; Cost Control; Diagnosis, Differential; Diagnostic Tests, Routine; Female; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Histidine; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Hematologic; Reticulocyte Count; Retrospective Studies; Sensitivity and Specificity; Time Factors; Urinalysis; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Serum methylmalonic acid and total homocysteine in patients with suspected cobalamin deficiency: a clinical study based on gastrointestinal histopathological findings.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Gastric Mucosa; Homocysteine; Humans; Intestinal Mucosa; Male; Methylmalonic Acid; Middle Aged; Neutrophils; Prospective Studies; Schilling Test; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
An external quality assessment study on the analysis of methylmalonic acid and total homocysteine in plasma.
Topics: Anticoagulants; Chelating Agents; Chemistry, Clinical; Edetic Acid; Evaluation Studies as Topic; Heparin; Homocysteine; Humans; Methylmalonic Acid; Quality Control; Reproducibility of Results; Sodium Fluoride | 1997 |
Serum homocysteine and methylmalonic acid in patients with rheumatoid arthritis and cobalaminopenia.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Pilot Projects; Retrospective Studies; Vitamin B 12 | 1998 |
Dietary intake of cobalamin in elderly people who have abnormal serum cobalamin, methylmalonic acid and homocysteine levels.
Topics: Aged; Aged, 80 and over; Diet; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Nutritional Status; Prospective Studies; Vitamin B 12 | 1998 |
The effect of vitamin B12 deficiency on older veterans and its relationship to health.
Topics: Aged; Aged, 80 and over; Alcohol Drinking; Analysis of Variance; Cognition Disorders; Cross-Sectional Studies; Educational Status; Female; Geriatric Assessment; Homocysteine; Humans; Income; Male; Methylmalonic Acid; Oklahoma; Reproducibility of Results; Veterans; Vitamin B 12; Vitamin B 12 Deficiency | 1998 |
Reliability of biochemical parameters used in prenatal diagnosis of combined methylmalonic aciduria and homocystinuria.
Topics: Amino Acid Metabolism, Inborn Errors; Amniocentesis; Amniotic Fluid; Cells, Cultured; Chorion; Chorionic Villi Sampling; Cobamides; Female; Gestational Age; Homocysteine; Homocystinuria; Humans; Male; Methylmalonic Acid; Pregnancy; Propionates; Tetrahydrofolates; Vitamin B 12 | 1998 |
Advantages of serum pepsinogen A combined with gastrin or pepsinogen C as first-line analytes in the evaluation of suspected cobalamin deficiency: a study in patients previously not subjected to gastrointestinal surgery.
Topics: Adult; Aged; Algorithms; Diagnosis, Differential; Female; Gastrins; Gastritis, Atrophic; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Pepsinogen A; Pepsinogen C; Predictive Value of Tests; Vitamin B 12 Deficiency | 1998 |
[Functional deficiency of vitamin B12 and folate. No "parameter" is "meter"].
Topics: Biomarkers; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Specimen Handling; Vitamin B 12 Deficiency | 1998 |
Cobalamin deficiency in general practice. Assessment of the diagnostic utility and cost-benefit analysis of methylmalonic acid determination in relation to current diagnostic strategies.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cohort Studies; Cost-Benefit Analysis; Family Practice; Female; Folic Acid; Homocysteine; Humans; Infant; Male; Methylmalonic Acid; Middle Aged; Practice Patterns, Physicians'; Reference Standards; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Holotranscobalamin - a sensitive marker of cobalamin malabsorption.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Atrophy; Female; Gastric Mucosa; Homocysteine; Humans; Intestinal Absorption; Male; Methylmalonic Acid; Middle Aged; Stomach; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Supplementation with vitamin B12 decreases homocysteine and methylmalonic acid but also serum folate in patients with end-stage renal disease.
Topics: Adult; Aged; Dietary Supplements; Female; Folic Acid; Folic Acid Antagonists; Genotype; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Vitamin B 12 | 1999 |
External quality assessment of methylmalonic acid and total homocysteine.
Topics: Chromatography, High Pressure Liquid; Clinical Laboratory Techniques; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Immunoassay; Laboratories, Hospital; Methylmalonic Acid; Quality Control | 1999 |
Turn of tide for oral vitamin B12 treatment.
Topics: Administration, Oral; Aged; Biological Availability; Biomarkers; England; Female; Homocysteine; Humans; Infusions, Intravenous; Methylmalonic Acid; Neural Tube Defects; Pregnancy; Pregnancy Complications; Sweden; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Schilling and protein-bound cobalamin absorption tests are poor instruments for diagnosing cobalamin malabsorption.
Topics: Adult; Atrophy; Duodenum; Female; Homocysteine; Humans; Intestinal Absorption; Male; Methylmalonic Acid; Reference Values; Reproducibility of Results; Schilling Test; Stomach; Sweden; Vitamin B 12; Vitamin B 12 Deficiency; Volunteers | 1997 |
Serum cobalamin, homocysteine, and methylmalonic acid concentrations in a multiethnic elderly population: ethnic and sex differences in cobalamin and metabolite abnormalities.
Topics: Aged; Analysis of Variance; Ethnicity; Female; Folic Acid; Homocysteine; Humans; Los Angeles; Male; Methylmalonic Acid; Middle Aged; Racial Groups; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Racial differences in prevalence of cobalamin and folate deficiencies in disabled elderly women.
Topics: Aged; Aged, 80 and over; Black People; Cross-Sectional Studies; Disabled Persons; Educational Status; Female; Folic Acid Deficiency; Homocysteine; Humans; Income; Methylmalonic Acid; Prevalence; Vitamin B 12 Deficiency; Vitamins; White People | 1999 |
Evidence of altered homocysteine metabolism in chronic renal failure.
Topics: Arteriosclerosis; Citrates; Creatinine; Cystathionine; Cysteine; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methionine; Methylmalonic Acid; Middle Aged; Renal Dialysis; Risk Factors; Vitamins | 1999 |
Evaluation of low serum vitamin B(12) in the non-anaemic pregnant patient.
Topics: Adult; Erythrocyte Indices; Female; Gestational Age; Homocysteine; Humans; Methylmalonic Acid; Parity; Pregnancy; Pregnancy Complications; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Concentrations of plasma methylmalonic acid in 80-year-olds show only weak relation to psychological performance.
Topics: Aged; Aged, 80 and over; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Methylmalonic Acid; Psychological Tests; Vitamin B 12 | 1999 |
Using homocysteine and related metabolites to diagnose vitamin deficiency states.
Topics: Aging; Animals; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12 Deficiency | 2000 |
Etiology and diagnostic evaluation of macrocytosis.
Topics: Adult; Aged; Alcohol Drinking; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow Diseases; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; L-Lactate Dehydrogenase; Leukocyte Count; Liver Diseases; Liver Diseases, Alcoholic; Male; Methylmalonic Acid; Middle Aged; Platelet Count; Predictive Value of Tests; Prospective Studies; Reticulocyte Count; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Inhibition of vitamin B12 metabolism by OH-cobalamin c-lactam in rat oligodendrocytes in culture: a model for studying neuropathy due to vitamin B12 deficiency.
Topics: Animals; Animals, Newborn; Cells, Cultured; Culture Media, Conditioned; Homocysteine; Humans; Methylmalonic Acid; Oligodendroglia; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Three siblings with nonketotic hyperglycinaemia, mildly elevated plasma homocysteine concentrations and moderate methylmalonic aciduria.
Topics: Child; Consanguinity; Female; Homocysteine; Humans; Hyperglycinemia, Nonketotic; Infant; Infant, Newborn; Leucovorin; Male; Methylmalonic Acid; Nuclear Family | 2000 |
Treatment of cobalamin deficiency in dementia, evaluated clinically and with cerebral blood flow measurements.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebrovascular Circulation; Dementia, Vascular; Female; Homocysteine; Humans; Hydroxocobalamin; Injections, Intramuscular; Male; Methylmalonic Acid; Regional Blood Flow; Vitamin B 12 Deficiency | 2000 |
[Evaluation of analytic test methods. Stomach-intestines status is the best diagnostic method in suspected vitamin B12 deficiency].
Topics: Biomarkers; Gastric Mucosa; Gastritis, Atrophic; Gastrointestinal Diseases; Gastroscopy; Homocysteine; Humans; Intestinal Mucosa; Methylmalonic Acid; Pepsinogen C; Practice Guidelines as Topic; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Evaluation of indicators of cobalamin deficiency defined as cobalamin-induced reduction in increased serum methylmalonic acid.
Topics: Adolescent; Aged; Aged, 80 and over; Female; Folic Acid; Gastroscopy; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Oxidation-Reduction; Regression Analysis; ROC Curve; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
EEG in assessing hydroxycobalamin therapy in neonatal methylmalonic aciduria with homocystinuria.
Topics: Electroencephalography; Female; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Infant, Newborn; Metabolism, Inborn Errors; Methylmalonic Acid | 2000 |
Vitamin B12 deficiency and incontinence in older people.
Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Prevalence; Prospective Studies; Urinary Incontinence; Vitamin B 12 Deficiency | 2000 |
Oral contraceptives can cause falsely low vitamin B(12) levels.
Topics: Adult; Contraceptives, Oral; Diagnostic Errors; False Positive Reactions; Female; Homocysteine; Humans; Methylmalonic Acid; Transcobalamins; Vitamin B 12 Deficiency | 2000 |
Role of homocysteine, cystathionine and methylmalonic acid measurement for diagnosis of vitamin deficiency in high-aged subjects.
Topics: Adult; Aged; Cystathionine; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Kidney; Male; Methylmalonic Acid; Middle Aged; Models, Chemical; Pyridoxine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2000 |
Evaluation of the cobalt requirement of beef cattle based on vitamin B12, folate, homocysteine and methylmalonic acid.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Cobalt; Homocysteine; Liver; Male; Methylmalonic Acid; Nutritional Requirements; Radioimmunoassay; Vitamin B 12 | 2000 |
Association of folate intake and serum homocysteine in elderly persons according to vitamin supplementation and alcohol use.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Coffee; Cross-Sectional Studies; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Life Style; Linear Models; Male; Methylmalonic Acid; Risk Factors; Smoking; Tea; Vascular Diseases; Vitamin B 12 | 2001 |
[Regarding the diagnosis of vitamin B 12 deficiency].
Topics: Age Factors; Biomarkers; Homocysteine; Humans; Methylmalonic Acid; Reference Values; Vitamin B 12 Deficiency | 2001 |
[Study of cobalamin deficiency in gastrectomized and aged subjects].
Topics: Age Factors; Aged; Creatinine; Data Interpretation, Statistical; Gastrectomy; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Serum cobalamin, folate, methylmalonic acid and total homocysteine as vitamin B12 and folate tissue deficiency markers amongst elderly Swedes--a population-based study.
Topics: Age Factors; Aged; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Population Surveillance; Sex Factors; Sweden; Vitamin B 12; Vitamins | 2001 |
Hyperhomocysteinemia and elevated methylmalonic acid indicate a high prevalence of cobalamin deficiency in Asian Indians.
Topics: Adult; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylmalonic Acid; Middle Aged; Prevalence; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Shifts in B12 opinions in primary health care of Sweden.
Topics: Attitude of Health Personnel; Biomarkers; Clinical Competence; Decision Making; Homocysteine; Humans; Methylmalonic Acid; Physicians, Family; Primary Health Care; Surveys and Questionnaires; Sweden; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Homocysteine and methylmalonic acid as indicators of folate and vitamin B12 deficiency in pregnancy.
Topics: Adult; Biomarkers; Female; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Pregnancy; Pregnancy Complications; Vitamin B 12 Deficiency | 2001 |
Genetic defects as important factors for moderate hyperhomocysteinemia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Age Factors; Aged; Aged, 80 and over; Cystathionine; DNA Mutational Analysis; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Protein Binding; Risk Factors; Sex Factors; Vitamin B 12; Vitamin B 6 | 2001 |
Homocysteine, cystathionine, methylmalonic acid and B-vitamins in patients with renal disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Cystathionine; Female; Homocysteine; Humans; Immunoassay; Kidney Diseases; Kidney Transplantation; Male; Methylmalonic Acid; Middle Aged; Renal Dialysis; Vitamin B Complex | 2001 |
Does a single vitamin B-supplementation induce functional vitamin B-deficiency?
Topics: Adult; Cystathionine; Cysteine; Dietary Supplements; Folic Acid; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Methionine; Methylmalonic Acid; Middle Aged; Models, Biological; Pilot Projects; Time Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2001 |
Homocysteine and methylmalonic acid levels in pregnant Nepali women. Should cobalamin supplementation be considered?
Topics: Adolescent; Adult; Biomarkers; Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Nepal; Nutritional Status; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
CblC/D defect combined with haemodynamically highly relevant VSD.
Topics: Female; Folic Acid; Heart Septal Defects, Ventricular; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Infant, Newborn; Lactic Acid; Metabolism, Inborn Errors; Methionine; Methylmalonic Acid | 2001 |
High prevalence of low serum vitamin B12 in a multi-ethnic Israeli population.
Topics: Adult; Arabs; Blood Donors; Case-Control Studies; Chi-Square Distribution; Female; Gaucher Disease; Homocysteine; Humans; Iraq; Israel; Jews; Male; Methylmalonic Acid; Morocco; Prevalence; Tunisia; Vitamin B 12; Vitamin B 12 Deficiency; Yemen | 2001 |
Total homocysteine is making its way into pediatric laboratory diagnostics.
Topics: Adult; Avitaminosis; Child; Diagnosis, Differential; Female; Folic Acid; Folic Acid Deficiency; HIV Infections; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Male; Methylmalonic Acid; Pediatrics; Pregnancy; Vitamin B 12 | 2001 |
Metabolism of amino acids in cats with severe cobalamin deficiency.
Topics: Amino Acids; Animals; Cat Diseases; Cats; Cystathionine; Cysteine; Female; Gastrointestinal Diseases; Homocysteine; Immunoassay; Male; Methionine; Methylmalonic Acid; Statistics, Nonparametric; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Vitamin B12 metabolism after urinary diversion with a Kock ileal reservoir.
Topics: Adult; Aged; Female; Follow-Up Studies; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Schilling Test; Urinary Diversion; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
[Methylmalonic acid in diagnosis of vitamin B12 deficiency].
Topics: Biomarkers; Homocysteine; Humans; Methylmalonic Acid; Reference Values; Vitamin B 12 Deficiency | 2002 |
[Diagnosis and vitamin B12 deficiency].
Topics: Biomarkers; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12 Deficiency | 2001 |
Vitamin B(12) deficiency associated with histamine(2)-receptor antagonists and a proton-pump inhibitor.
Topics: Aged; Cimetidine; Creatinine; Enzyme Inhibitors; Female; Folic Acid; Gastroesophageal Reflux; Histamine H2 Antagonists; Homocysteine; Humans; Methylmalonic Acid; Omeprazole; Proton Pump Inhibitors; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Methylenetetrahydrofolate reductase genotype, vitamin B12, and folate influence plasma homocysteine in hemodialysis patients.
Topics: Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Renal Dialysis; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Genetic and molecular control of folate-homocysteine metabolism in mutant mice.
Topics: Animals; Blotting, Northern; Disease Models, Animal; Female; Folic Acid; Gene Expression Regulation; Homocysteine; Hyperhomocysteinemia; Liver; Methylmalonic Acid; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Oligonucleotide Array Sequence Analysis; Signal Transduction | 2002 |
Early-onset cobalamin C/D deficiency: epilepsy and electroencephalographic features.
Topics: Age of Onset; Brain; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Homocysteine; Homocystine; Homocystinuria; Humans; Infant; Infant, Newborn; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Sleep; Vitamin B 12; Vitamin B 12 Deficiency; Wakefulness | 2002 |
Vitamin B12 and folate after 5-12 years of continent ileal urostomy (Kock reservoir) in children and adolescents.
Topics: Adolescent; Child; Child Welfare; Colonic Pouches; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Glomerular Filtration Rate; Hemoglobins; Homocysteine; Humans; Ileum; Iron; Kidney; Male; Methylmalonic Acid; Postoperative Complications; Prospective Studies; Time Factors; Ureterostomy; Urinary Reservoirs, Continent; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Transcobalamin II 775G>C polymorphism and indices of vitamin B12 status in healthy older adults.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Is low-dose oral cobalamin enough to normalize cobalamin function in older people?
Topics: Administration, Oral; Aged; Aged, 80 and over; Cross-Sectional Studies; Dietary Supplements; Female; Homocysteine; Humans; Male; Methylglycosides; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Cobalamin disorder Cbl-C presenting with late-onset thrombotic microangiopathy.
Topics: Age of Onset; Child; Child, Preschool; Female; Hematinics; Hematuria; Hemolysis; Hemolytic-Uremic Syndrome; Homocysteine; Humans; Hydroxocobalamin; Kidney; Male; Methylmalonic Acid; Microcirculation; Proteinuria; Thrombosis; Vitamin B 12 Deficiency | 2002 |
Elevated serum methylmalonic acid concentrations are common among elderly Americans.
Topics: Adult; Aged; Aging; Black or African American; Creatinine; Female; Folic Acid; Hispanic or Latino; Homocysteine; Humans; Male; Methylmalonic Acid; Nutrition Surveys; Vitamin B 12; Vitamin B 12 Deficiency; White People | 2002 |
Optimal use of markers for cobalamin and folate status in a psychogeriatric population.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Vitamin B 12 | 2002 |
Evaluation of the DPC IMMULITE 2000 assay for total homocysteine in plasma.
Topics: Chemistry, Clinical; Evaluation Studies as Topic; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Methylmalonic Acid; Quality Control | 2002 |
Cobalamin status (holo-transcobalamin, methylmalonic acid) and folate as determinants of homocysteine concentration.
Topics: Adult; Aged; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12 | 2002 |
Homocysteine and methylmalonic acid: markers to predict and avoid toxicity from pemetrexed therapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Folic Acid; Glutamates; Guanine; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Models, Biological; Multivariate Analysis; Odds Ratio; Pemetrexed; Time Factors; Vitamin B 12 | 2002 |
Hyperhomocysteinemia and vitamin B-12 deficiency are more striking in Syrians than in Germans--causes and implications.
Topics: Adult; Arabs; Cholesterol, LDL; Coronary Disease; Female; Germany; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Middle Aged; Prevalence; Syria; Vitamin D Deficiency | 2003 |
Predictors of cobalamin deficiency in Guatemalan school children: diet, Helicobacter pylori, or bacterial overgrowth?
Topics: Analysis of Variance; Breath Tests; Child; Diet; Female; Gastrins; Guatemala; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Male; Methylmalonic Acid; Pepsinogen A; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
High prevalence of cobalamin deficiency in Guatemalan schoolchildren: associations with low plasma holotranscobalamin II and elevated serum methylmalonic acid and plasma homocysteine concentrations.
Topics: Analysis of Variance; Anemia; Biomarkers; Child; Creatinine; Female; Folic Acid; Guatemala; Hematocrit; Hemoglobins; Homocysteine; Humans; Male; Mass Screening; Methylmalonic Acid; Prevalence; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Relationship between methylmalonic acid, homocysteine, vitamin B12 intake and status and socio-economic indices, in a subset of participants in the British National Diet and Nutrition Survey of people aged 65 y and over.
Topics: Aged; Analysis of Variance; Cross-Sectional Studies; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Nutrition Surveys; Nutritional Status; Socioeconomic Factors; United Kingdom; Vitamin B 12 | 2003 |
Serum levels of total homocysteine, homocysteine metabolites and of advanced glycation end-products (AGEs) in patients after renal transplantation.
Topics: Adult; Arginine; Coronary Disease; Cystathionine; Female; Glycation End Products, Advanced; Homocysteine; Humans; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Kidney Transplantation; Logistic Models; Lysine; Male; Methylmalonic Acid; Middle Aged; Risk Factors | 2003 |
Vitamin B-12 status is associated with bone mineral content and bone mineral density in frail elderly women but not in men.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Body Composition; Body Height; Body Weight; Bone Density; Calcium, Dietary; Female; Frail Elderly; Homocysteine; Humans; Male; Methylmalonic Acid; Netherlands; Nutritional Status; Odds Ratio; Osteoporosis; Parathyroid Hormone; Regression Analysis; Sex Characteristics; Smoking; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D | 2003 |
Folate deficiency is a common finding in psychogeriatric patients.
Topics: Aged; Aged, 80 and over; Aging; Cognition Disorders; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Regression Analysis; Vitamin B 12 | 2002 |
Screening for vitamin B-12 and folate deficiency in older persons.
Topics: Age Factors; Aged; Aged, 80 and over; Creatinine; Female; Folic Acid; Folic Acid Deficiency; Hemoglobins; Homocysteine; Humans; Male; Mass Screening; Methylmalonic Acid; Prevalence; Reference Values; Risk Factors; Sex Factors; United Kingdom; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Anemia, serum vitamin B12, and folic acid in patients with rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Arthritis, Psoriatic; Arthritis, Rheumatoid; Cohort Studies; Female; Folic Acid Deficiency; Homocysteine; Humans; Incidence; Israel; Lupus Erythematosus, Systemic; Male; Methylmalonic Acid; Middle Aged; Retrospective Studies; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism and the B-vitamins: a facet of nature-nurture interplay.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6 | 2003 |
Urine methylmalonic acid measurements for the assessment of cobalamin deficiency related to neuropsychiatric disorders.
Topics: Adult; Aged; Folic Acid; Homocysteine; Humans; Mental Disorders; Methylmalonic Acid; Middle Aged; Photometry; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Increased plasma homocysteine levels without signs of vitamin B12 deficiency in patients with multiple sclerosis assessed by blood and cerebrospinal fluid homocysteine and methylmalonic acid.
Topics: Adult; Aged; Aged, 80 and over; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Multiple Sclerosis; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Vitamin B-12 status, particularly holotranscobalamin II and methylmalonic acid concentrations, and hyperhomocysteinemia in vegetarians.
Topics: Adult; Aged; Biomarkers; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Middle Aged; Osmolar Concentration; Transcobalamins; Vitamin B 12 | 2003 |
Myeloneuropathy from nitrous oxide abuse: unusually high methylmalonic acid and homocysteine levels.
Topics: Adult; Anesthetics, Inhalation; Demyelinating Diseases; Diagnosis, Differential; Homocysteine; Humans; Male; Methylmalonic Acid; Nitrous Oxide; Vitamin B 12 Deficiency | 2003 |
Reported symptoms and clinical findings in relation to serum cobalamin, folate, methylmalonic acid and total homocysteine among elderly Swedes: a population-based study.
Topics: Aged; Atrophy; Cohort Studies; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Male; Methylmalonic Acid; Mouth Diseases; Mouth Mucosa; Stomatitis; Tongue; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Challenges in the identification of cobalamin-deficiency polyneuropathy.
Topics: Adult; Aged; Aged, 80 and over; Anemia, Pernicious; Female; Follow-Up Studies; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Polyneuropathies; Vitamin B 12 Deficiency | 2003 |
Cobalamin, folate, methylmalonic acid, homocysteine, and gastritis markers in dementia.
Topics: Biomarkers; Case-Control Studies; Dementia; Folic Acid; Gastritis; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Risk Factors; Vitamin B 12 | 2003 |
B vitamin status and concentrations of homocysteine and methylmalonic acid in elderly German women.
Topics: Aged; Anthropometry; Diet; Female; Geriatric Assessment; Germany; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Nutritional Status; Vitamin B Complex | 2003 |
Routine determination of serum methylmalonic acid and plasma total homocysteine in Norway.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Clinical Laboratory Techniques; Creatinine; Female; Folic Acid; Homocysteine; Humans; Infant; Male; Methylmalonic Acid; Middle Aged; Norway; Sex Factors; Vitamin B 12 | 2003 |
Cobalamin status and its biochemical markers methylmalonic acid and homocysteine in different age groups from 4 days to 19 years.
Topics: Adolescent; Adult; Biomarkers; Child; Child, Preschool; Cross-Sectional Studies; Female; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methylmalonic Acid; Reference Values; Vitamin B 12 | 2003 |
Functional vitamin B12 deficiency and determination of holotranscobalamin in populations at risk.
Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Diet, Vegetarian; Female; Folic Acid; Germany; Homocysteine; Humans; Kidney Diseases; Male; Methylmalonic Acid; Middle Aged; Risk; Syria; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Holotranscobalamin as a predictor of vitamin B12 status.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Forecasting; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Radioligand Assay; Transcobalamins; Vitamin B 12 Deficiency | 2003 |
Comparison of the influence of volume-oriented training and high-intensity interval training on serum homocysteine and its cofactors in young, healthy swimmers.
Topics: Adolescent; Anthropometry; Exercise; Folic Acid; Heart Rate; Homocysteine; Humans; Methylmalonic Acid; Reference Values; Swimming; Time Factors; Vitamin B 12; Vitamin B 6 | 2003 |
Metabolic markers of cobalamin deficiency and cognitive function in normal older adults.
Topics: Aged; Citric Acid; Cognition; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Methylmalonic Acid; Statistics, Nonparametric; Vitamin B 12 | 2004 |
Vitamin B12 status in the elderly as judged by available biochemical markers.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12; Vitamin B 6 | 2004 |
Hematological parameters and cobalamin status in infants born to smoking mothers.
Topics: Adult; Birth Weight; Erythrocyte Count; Female; Folic Acid; Gestational Age; Hemoglobins; Homocysteine; Humans; Infant; Infant, Newborn; Logistic Models; Maternal-Fetal Exchange; Methylmalonic Acid; Pregnancy; Smoking; Vitamin B 12 | 2004 |
Urinary methylmalonic acid test may have greater value than the total homocysteine assay for screening elderly individuals for cobalamin deficiency.
Topics: Aged; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12 Deficiency | 2004 |
Homocysteine and the risk of ischemic stroke in a triethnic cohort: the NOrthern MAnhattan Study.
Topics: Aged; Black People; Cohort Studies; Female; Hispanic or Latino; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Vascular Diseases; White People | 2004 |
Cobalamin-responsive disorders in the ambulatory care setting: unreliability of cobalamin, methylmalonic acid, and homocysteine testing.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Health Maintenance Organizations; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Reproducibility of Results; Retrospective Studies; Treatment Outcome; Treatment Refusal; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
A population-based intervention study on elevated serum levels of methylmalonic acid and total homocysteine in elderly people: results after 36 months of follow-up.
Topics: Aged; Cohort Studies; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Longitudinal Studies; Male; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
Response of homocysteine, cystathionine, and methylmalonic acid to vitamin treatment in dialysis patients.
Topics: Aged; Aged, 80 and over; Cystathionine; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylmalonic Acid; Middle Aged; Renal Dialysis; Vitamin B 12; Vitamin B 6 | 2005 |
Alteration of homocysteine catabolism in pre-eclampsia, HELLP syndrome and placental insufficiency.
Topics: Cystathionine; Cystatin C; Cystatins; Female; Folic Acid; HELLP Syndrome; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Methylmalonic Acid; Oxidative Stress; Placental Insufficiency; Pre-Eclampsia; Pregnancy; Severity of Illness Index; Uric Acid; Vitamin B 12; Vitamin B 6 | 2004 |
Cellular uptake of vitamin B12 in patients with chronic renal failure.
Topics: Adult; Aged; Cells, Cultured; Cystathionine; Female; Homocysteine; Humans; Kidney Failure, Chronic; Leukocytes, Mononuclear; Male; Methylmalonic Acid; Middle Aged; Vitamin B 12 | 2005 |
Effects of intramuscular injections of vitamin B12 on lactation performance of dairy cows fed dietary supplements of folic acid and rumen-protected methionine.
Topics: Animals; Cattle; Cysteine; Diet; Dietary Supplements; Eating; Female; Folic Acid; Homocysteine; Injections, Intramuscular; Lactation; Methionine; Methylmalonic Acid; Milk; Parity; Rumen; Vitamin B 12 | 2005 |
Effects of oral contraceptives and hormone replacement therapy on markers of cobalamin status.
Topics: Adolescent; Adult; Aged; Contraceptives, Oral, Combined; Cross-Sectional Studies; Estrogen Replacement Therapy; Female; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12 | 2005 |
Cobalamin deficiency in elderly patients.
Topics: Aged; Algorithms; Canada; Folic Acid; Food, Fortified; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Disturbed homocysteine and methionine cycle intermediates S-adenosylhomocysteine and S-adenosylmethionine are related to degree of renal insufficiency in type 2 diabetes.
Topics: Aged; Cystathionine; Cysteine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Folic Acid; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Male; Methionine; Methylmalonic Acid; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcobalamins; Vitamin B 12; Vitamin B 6 | 2005 |
Creatine metabolism in combined methylmalonic aciduria and homocystinuria.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Creatine; Female; Glycine; Homocysteine; Homocystinuria; Humans; Male; Methionine; Methylmalonic Acid; Vitamin B 12 | 2005 |
Executive dysfunction in hyperhomocystinemia responds to homocysteine-lowering treatment.
Topics: Adult; Anticoagulants; Betaine; Cognition Disorders; Confusion; Disease Progression; Drug Therapy, Combination; Folic Acid; Frontal Lobe; Homocysteine; Humans; Hyperhomocysteinemia; Leukoaraiosis; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Remission Induction; Seizures; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2005 |
Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans.
Topics: Aged; Bone Density; Female; Folic Acid; Hip; Homocysteine; Humans; Male; Methylmalonic Acid; Osteoporosis; Radiography; United States; Vitamin B 12 | 2005 |
Cobalamin-responsive disorders and unreliability of cobalamin, methylmalonic acid, and homocysteine testing.
Topics: Diagnostic Errors; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Maculopathy and retinal degeneration in cobalamin C methylmalonic aciduria and homocystinuria.
Topics: Amino Acid Metabolism, Inborn Errors; Betaine; Cobamides; Female; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Infant; Macula Lutea; Methionine; Methylmalonic Acid; Retina; Retinal Degeneration; Vision, Ocular; Visual Acuity; Vitamin B 12 Deficiency | 2005 |
Biochemical indicators of B vitamin status in the US population after folic acid fortification: results from the National Health and Nutrition Examination Survey 1999-2000.
Topics: Adult; Aged; Dietary Supplements; Erythrocytes; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Nutrition Surveys; Reference Values; Time Factors; United States; Vitamin B 12 | 2005 |
Automated assay for the determination of methylmalonic acid, total homocysteine, and related amino acids in human serum or plasma by means of methylchloroformate derivatization and gas chromatography-mass spectrometry.
Topics: Amino Acids; Autoanalysis; Formates; Gas Chromatography-Mass Spectrometry; Glycine; Homocysteine; Humans; Indicators and Reagents; Methionine; Methylmalonic Acid; Plasma; Reference Values; Sensitivity and Specificity; Serine; Serum | 2005 |
Folate and vitamin B12 in relation to lactation: a 9-month postpartum follow-up study.
Topics: Adult; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lactation; Life Style; Methylmalonic Acid; Nutritional Requirements; Nutritional Status; Postpartum Period; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Homocysteine and methylmalonic acid concentrations in cerebrospinal fluid: relation with age and Alzheimer's disease.
Topics: Adult; Aged; Alzheimer Disease; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged | 2005 |
Altered vitamin B12 status in recreational endurance athletes.
Topics: Adult; Biomarkers; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Nutritional Status; Physical Endurance; Vitamin B 12; Vitamin B Complex | 2005 |
A daily intake of approximately 6 microg vitamin B-12 appears to saturate all the vitamin B-12-related variables in Danish postmenopausal women.
Topics: Administration, Oral; Adult; Aged; Denmark; Diet; Diet Records; Dietary Supplements; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Nutritional Status; Postmenopause; Statistics, Nonparametric; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2006 |
Two newborns with nutritional vitamin B12 deficiency: challenges in newborn screening for vitamin B12 deficiency.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Anemia, Pernicious; Autoimmune Diseases; Biomarkers; Carnitine; Citrates; Cystathionine; False Negative Reactions; Female; Gastric Bypass; Heterozygote; Homocysteine; Humans; Hydroxocobalamin; Infant Food; Infant, Newborn; Malabsorption Syndromes; Male; Mass Spectrometry; Maternal-Fetal Exchange; Methylmalonic Acid; Neonatal Screening; Pregnancy; Pregnancy Complications; Vitamin B 12 Deficiency | 2005 |
Cobalamin status during normal pregnancy and postpartum: a longitudinal study comprising 406 Danish women.
Topics: Adult; Cohort Studies; Denmark; Female; Follow-Up Studies; Hemoglobins; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Postpartum Period; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimester, Third; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
[Oral treatment of vitamin B12 deficiency in subacute combined degeneration].
Topics: Administration, Oral; Adult; Anemia, Pernicious; Autoantibodies; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Intrinsic Factor; Magnetic Resonance Imaging; Methylmalonic Acid; Neurologic Examination; Spinal Cord; Spinal Cord Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Clinical and biochemical studies on Chinese patients with methylmalonic aciduria.
Topics: Adolescent; Adult; Age of Onset; Amino Acid Metabolism, Inborn Errors; Biomarkers; Child; Child, Preschool; China; Chronic Disease; Comorbidity; Disease Progression; Female; Homocysteine; Homocystinuria; Humans; Infant; Infant, Newborn; Male; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Predictive Value of Tests; Prognosis; Survival Rate | 2006 |
Biomarkers of folate and vitamin B12 are related in blood and cerebrospinal fluid.
Topics: Adult; Aged; Aging; Biomarkers; Cystathionine; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12 | 2007 |
Glomerular filtration rate as measured by serum cystatin C is an important determinant of plasma homocysteine and serum methylmalonic acid in the elderly.
Topics: Aged; Avitaminosis; Biomarkers; Creatinine; Cystatin C; Cystatins; Female; Folic Acid; Folic Acid Deficiency; Glomerular Filtration Rate; Homocysteine; Humans; Kidney; Male; Methylmalonic Acid; Nutritional Status; Regression Analysis; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2007 |
Renal impairment compromises the use of total homocysteine and methylmalonic acid but not total vitamin B12 and holotranscobalamin in screening for vitamin B12 deficiency in the aged.
Topics: Aged; Aged, 80 and over; Homocysteine; Humans; Kidney Diseases; Methods; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Holotranscobalamin and methylmalonic acid as prognostic markers following an acute myocardial infarction.
Topics: Acute Disease; Aged; Aged, 80 and over; Biomarkers; Female; Follow-Up Studies; Homocysteine; Humans; Male; Methylmalonic Acid; Myocardial Infarction; Odds Ratio; Prognosis; Recurrence; Time Factors; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Association between decreased vitamin levels and MTHFR, MTR and MTRR gene polymorphisms as determinants for elevated total homocysteine concentrations in pregnant women.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Alleles; Analysis of Variance; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Young Adult | 2008 |
Cobalamin deficiency-induced down-regulation of p75-immunoreactive cell levels in rat central nervous system.
Topics: Animals; Central Nervous System; Down-Regulation; Gastrectomy; Homocysteine; Immunohistochemistry; Male; Methylmalonic Acid; Nerve Fibers, Myelinated; Nerve Growth Factor; Rats; Rats, Sprague-Dawley; Receptor, Nerve Growth Factor; Recovery of Function; Septal Nuclei; Spinal Cord; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Reference intervals for haematological variables during normal pregnancy and postpartum in 434 healthy Danish women.
Topics: Creatinine; Denmark; Female; Ferritins; Folic Acid; Hematologic Tests; Homocysteine; Humans; Methylmalonic Acid; Postpartum Period; Pregnancy; Receptors, Transferrin; Reference Values; Vitamin B 12 | 2007 |
Influence of different dietary levels of zinc on performance, vitamin B12, and blood parameters in lambs.
Topics: Animal Feed; Animals; Blood Glucose; Body Weight; Cobalt; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Methylmalonic Acid; Rumen; Sheep; Vitamin B 12; Zinc | 2006 |
Folate, but not vitamin B-12 status, predicts respiratory morbidity in north Indian children.
Topics: Acute Disease; Child, Preschool; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Incidence; India; Infant; Male; Methylmalonic Acid; Multivariate Analysis; Prospective Studies; Regression Analysis; Respiratory Tract Infections; Risk Factors; Vitamin B 12 | 2007 |
Marfanoid features in a child with combined methylmalonic aciduria and homocystinuria (CblC type).
Topics: Adolescent; Carnitine; Carrier Proteins; Child; Cysteine; Diagnosis, Differential; DNA Mutational Analysis; Exons; Female; Folic Acid; Genetic Testing; Heterozygote; Homocysteine; Homocystinuria; Humans; Male; Marfan Syndrome; Metabolism, Inborn Errors; Methylmalonic Acid; Mutation; Oxidoreductases; Pedigree; Phenotype; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamins | 2007 |
Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study.
Topics: Adipose Tissue; Anthropometry; Body Composition; Body Mass Index; Child; Female; Folic Acid; Homocysteine; Humans; Insulin Resistance; Male; Methylmalonic Acid; Pregnancy; Pregnancy Complications; Vitamin B 12 | 2008 |
West syndrome in an infant with vitamin B12 deficiency in the absence of macrocytic anaemia.
Topics: Anemia, Macrocytic; Brain; Diagnosis, Differential; Electroencephalography; Female; Homocysteine; Humans; Infant; Methylmalonic Acid; Spasms, Infantile; Vitamin B 12 Deficiency | 2007 |
Low vitamin B-12 status and risk of cognitive decline in older adults.
Topics: Aged; Aged, 80 and over; Cognition Disorders; Cohort Studies; Female; Homocysteine; Humans; Longitudinal Studies; Male; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
The association of gastric cancer risk with plasma folate, cobalamin, and methylenetetrahydrofolate reductase polymorphisms in the European Prospective Investigation into Cancer and Nutrition.
Topics: Adult; Aged; Case-Control Studies; Cohort Studies; Europe; Female; Folic Acid; Gastritis, Atrophic; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Polymorphism, Single Nucleotide; Prospective Studies; Risk Factors; Stomach Neoplasms; Vitamin B 12 | 2007 |
Evaluation of nutritional and genetic determinants of total homocysteine, methylmalonic acid and S-adenosylmethionine/S-adenosylhomocysteine values in Brazilian childbearing-age women.
Topics: Adult; Aging; Alleles; Anemia, Iron-Deficiency; Avitaminosis; Brazil; Female; Genotype; Homocysteine; Humans; Methylmalonic Acid; Nutritional Physiological Phenomena; Polymorphism, Genetic; Reproduction; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamins | 2008 |
In vitamin B12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Time Factors; Vitamin B 12 Deficiency | 2007 |
Methylmalonic acid values in healthy Dutch children.
Topics: Adolescent; Adult; Aging; Biomarkers; Child; Child, Preschool; Creatinine; Cross-Sectional Studies; Female; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methylmalonic Acid; Netherlands; Reference Values; Regression Analysis; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
In vitamin B12 deficiency, higher serum folate is associated with increased homocysteine and methylmalonic acid concentrations.
Topics: Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12 Deficiency | 2008 |
Prenatal diagnosis of methylmalonic aciduria by analysis of organic acids and total homocysteine in amniotic fluid.
Topics: Amniotic Fluid; Carnitine; Citrates; Female; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Methylmalonic Acid; Pregnancy; Prenatal Diagnosis; Spectrometry, Mass, Electrospray Ionization | 2008 |
A fast liquid chromatographic tandem mass spectrometric method for the simultaneous determination of total homocysteine and methylmalonic acid.
Topics: Chromatography, Liquid; Homocysteine; Humans; Methylmalonic Acid; Succinic Acid; Tandem Mass Spectrometry; Time Factors | 2008 |
Gas chromatographic-mass spectrometric analysis of biomarkers related to folate and cobalamin status in human serum after dimercaptopropanesulfonate reduction and heptafluorobutyl chloroformate derivatization.
Topics: Alkanesulfonic Acids; Biomarkers; Fluorocarbons; Folic Acid; Formates; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Methylmalonic Acid; Oxidation-Reduction; Sulfhydryl Compounds; Vitamin B 12 | 2008 |
Folate and cobalamin status in relation to breastfeeding and weaning in healthy infants.
Topics: Age Distribution; Analysis of Variance; Breast Feeding; Child, Preschool; Diet Records; Female; Folic Acid; Homocysteine; Humans; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Longitudinal Studies; Male; Methylmalonic Acid; Norway; Nutritional Status; Reference Values; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex; Weaning | 2008 |
Neuropathy as a potential complication of levodopa use in Parkinson's disease.
Topics: Analysis of Variance; Antiparkinson Agents; Female; Homocysteine; Humans; Levodopa; Male; Methylmalonic Acid; Parkinson Disease; Peripheral Nervous System Diseases; Retrospective Studies; Vitamin B 12 | 2008 |
[Thromboembolic events, abortions and a sick infant--unusual presentation of a vitamin deficiency].
Topics: Abortion, Habitual; Adult; Anemia, Pernicious; Autoimmune Diseases; Breast Feeding; Diagnosis, Differential; Failure to Thrive; Female; Folic Acid; Gastritis, Atrophic; Homocysteine; Humans; Infant; Intrinsic Factor; Methylmalonic Acid; Parietal Cells, Gastric; Pregnancy; Thromboembolism; Vitamin B 12 Deficiency | 2008 |
Relationships between gene polymorphisms of folate-related proteins and vitamins and metabolites in pregnant women and neonates.
Topics: Adult; Brazil; DNA; Embryonic Development; Ethnicity; Female; Folic Acid; Glutamate Carboxypeptidase II; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Pregnancy; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylhomocysteine; S-Adenosylmethionine; Socioeconomic Factors; Vitamin B 12; Vitamin B Complex; Young Adult | 2008 |
B-vitamin and homocysteine status determines ovarian response to gonadotropin treatment in sheep.
Topics: Animals; Cells, Cultured; Diet; Female; Gene Expression Regulation; Gonadotropins; Granulosa Cells; Homocysteine; Methylmalonic Acid; Ovarian Follicle; Ovary; Ovulation; Ovulation Induction; Sheep; Vitamin B Complex; Vitamin B Deficiency | 2009 |
Folate-vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aging; Anemia, Pernicious; Cognition Disorders; Drug Interactions; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Middle Aged; Nutrition Surveys; Nutritional Status; Odds Ratio; Prevalence; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
Association between Helicobacter pylori-infection, C-reactive protein and status of B vitamins.
Topics: C-Reactive Protein; Cross-Sectional Studies; Female; Folic Acid; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Risk Factors; Vitamin B 12; Vitamin B 6 | 2008 |
Urinary methylmalonic acid levels in patients with acute ischemic stroke.
Topics: Aged; Aged, 80 and over; Brain Ischemia; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Stroke; Vitamin B 12 | 2009 |
Genetic polymorphisms involved in folate metabolism and concentrations of methylmalonic acid and folate on plasma homocysteine and risk of coronary artery disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Case-Control Studies; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Polymorphism, Genetic; Risk Factors | 2010 |
Vitamin B(12) deficiency stimulates osteoclastogenesis via increased homocysteine and methylmalonic acid.
Topics: Animals; Bone and Bones; Bone Density; Bone Remodeling; Cell Differentiation; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Homocysteine; Humans; Male; Methylmalonic Acid; Mice; Mice, Inbred C57BL; Osteoclasts; Osteoporosis; Up-Regulation; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
Metabolic evidence of vitamin B-12 deficiency, including high homocysteine and methylmalonic acid and low holotranscobalamin, is more pronounced in older adults with elevated plasma folate.
Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12 Deficiency | 2009 |
Subclinical vitamin B12 deficiency in pregnant women attending an antenatal clinic in Nigeria.
Topics: Adult; Ambulatory Care Facilities; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Methylmalonic Acid; Nigeria; Pregnancy; Pregnancy Complications; Prenatal Care; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2009 |
Association of metformin, elevated homocysteine, and methylmalonic acid levels and clinically worsened diabetic peripheral neuropathy.
Topics: Aged; Case-Control Studies; Chromatography, High Pressure Liquid; Diabetic Neuropathies; Electrophysiology; Female; Homocysteine; Humans; Hypoglycemic Agents; Immunoassay; Male; Mass Spectrometry; Metformin; Methylmalonic Acid; Middle Aged; Peripheral Nervous System Diseases; Prospective Studies; Vitamin B 12 | 2010 |
Double aneuploidy (48,XXY,+21) of maternal origin in a child born to a 13-year-old mother: evaluation of the maternal folate metabolism.
Topics: Adolescent; Alleles; Aneuploidy; Brazil; Chromosomes, Human, X; Chromosomes, Human, Y; DNA Mutational Analysis; Down Syndrome; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Carrier Screening; Genotype; Heart Defects, Congenital; Homocysteine; Homozygote; Humans; Infant; Klinefelter Syndrome; Male; Meiosis; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Nondisjunction, Genetic; Polymorphism, Genetic; Pregnancy; Pregnancy in Adolescence; Sex Chromosome Aberrations; Trisomy | 2009 |
Does high folic acid intake affect unrecognized cobalamin deficiency, and how will we know it if we see it?
Topics: Cognition; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Vitamin B 12 Deficiency | 2009 |
Metabolic signs of vitamin B(12) deficiency in humans: computational model and its implications for diagnostics.
Topics: Computer Simulation; Homocysteine; Humans; Methylmalonic Acid; Probability; ROC Curve; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2010 |
Daily intake of 4 to 7 microg dietary vitamin B-12 is associated with steady concentrations of vitamin B-12-related biomarkers in a healthy young population.
Topics: Adolescent; Adult; Antibodies, Bacterial; Autoantibodies; Biomarkers; Diet; Dose-Response Relationship, Drug; Female; Helicobacter pylori; Homocysteine; Humans; Intrinsic Factor; Male; Methylmalonic Acid; Middle Aged; Nutrition Policy; Nutritional Requirements; Nutritional Status; Reference Values; Vitamin B 12; Vitamin B Complex; Young Adult | 2010 |
A novel mutation in LMBRD1 causes the cblF defect of vitamin B(12) metabolism in a Turkish patient.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alleles; Female; Fibroblasts; Homocysteine; Humans; Lysosomes; Male; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Mutation; Nucleocytoplasmic Transport Proteins; Turkey; Vitamin B 12 | 2010 |
Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older Hispanics.
Topics: Aged; Aging; Analysis of Variance; California; Female; Genotype; Health Surveys; Hispanic or Latino; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylmalonic Acid; Middle Aged; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12; Vitamin B Complex; White People | 2010 |
Should transcobalamin deficiency be treated aggressively?
Topics: Anemia, Megaloblastic; Biological Transport; DNA Mutational Analysis; DNA Primers; Female; Homocysteine; Humans; Infant; Infant, Newborn; Methionine; Methylmalonic Acid; Mutation; Polymerase Chain Reaction; Protein Structure, Tertiary; Transcobalamins | 2010 |
Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors.
Topics: Aged; Aging; Anemia; Anemia, Macrocytic; Blood Cell Count; Cognition; Cognition Disorders; Cystatin C; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Linear Models; Male; Methylmalonic Acid; Multivariate Analysis; Nutrition Surveys; Tetrahydrofolates; United States; Vitamin B 12 Deficiency | 2010 |
Positive newborn screen for methylmalonic aciduria identifies the first mutation in TCblR/CD320, the gene for cellular uptake of transcobalamin-bound vitamin B(12).
Topics: Amino Acid Sequence; Antigens, CD; Base Sequence; Cells, Cultured; DNA Mutational Analysis; Female; Fibroblasts; Homocysteine; Humans; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methylmalonic Acid; Molecular Sequence Data; Mutation; Neonatal Screening; Pregnancy; Receptors, Cell Surface; Transcobalamins; Vitamin B 12 | 2010 |
Unmetabolized serum folic acid and its relation to folic acid intake from diet and supplements in a nationally representative sample of adults aged > or =60 y in the United States.
Topics: Aged; Diet; Dietary Supplements; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Nutrition Surveys; Tetrahydrofolates; United States; Vitamin B 12 | 2010 |
Vitamin B12-responsive severe leukoencephalopathy and autonomic dysfunction in a patient with "normal" serum B12 levels.
Topics: Autoantibodies; Autonomic Nervous System Diseases; Brain; Cognition Disorders; Depressive Disorder; Drug Therapy, Combination; Female; Homocysteine; Humans; Intrinsic Factor; Leukoencephalopathies; Magnetic Resonance Imaging; Mental Status Schedule; Methylmalonic Acid; Middle Aged; Neurologic Examination; Psychometrics; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D | 2010 |
Elevated levels of methylmalonate and homocysteine in Parkinson's disease, progressive supranuclear palsy and amyotrophic lateral sclerosis.
Topics: Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Matched-Pair Analysis; Methylmalonic Acid; Middle Aged; Parkinson Disease; Reference Values; Supranuclear Palsy, Progressive; Vitamin B 12 | 2010 |
Methylmalonic aciduria and homocystinuria-associated maculopathy.
Topics: Amino Acid Metabolism, Inborn Errors; Child, Preschool; Homocysteine; Homocystinuria; Humans; Macula Lutea; Male; Methylmalonic Acid; Retinal Degeneration | 2010 |
Determination of total homocysteine, methylmalonic acid, and 2-methylcitric acid in dried blood spots by tandem mass spectrometry.
Topics: Blood Specimen Collection; Chromatography, Liquid; Citrates; False Positive Reactions; Homocysteine; Humans; Infant, Newborn; Limit of Detection; Methylmalonic Acid; Neonatal Screening; Predictive Value of Tests; Reference Values; Tandem Mass Spectrometry | 2010 |
Anemia in older persons.
Topics: Aged; Algorithms; Anemia; Deficiency Diseases; Erythrocyte Indices; Female; Ferritins; Folic Acid; Hematinics; Homocysteine; Humans; Inflammation; Iron Compounds; Male; Medical History Taking; Methylmalonic Acid; Physical Examination; Renal Insufficiency; Reticulocyte Count; Vitamin B 12 | 2010 |
Clinical, biochemical, and molecular analysis of combined methylmalonic acidemia and hyperhomocysteinemia (cblC type) in China.
Topics: Amino Acid Metabolism, Inborn Errors; Biomarkers; Carnitine; Carrier Proteins; Child, Preschool; China; Codon, Nonsense; DNA Mutational Analysis; Exons; Gas Chromatography-Mass Spectrometry; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Heterozygote; Homocysteine; Homocystinuria; Homozygote; Humans; Infant; Infant, Newborn; Methylmalonic Acid; Oxidoreductases; Phenotype; Vitamin B 12 Deficiency | 2010 |
Serum vitamin B12 concentrations within reference values do not exclude functional vitamin B12 deficiency in PKU patients of various ages.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Female; Homocysteine; Humans; Infant; Male; Methylmalonic Acid; Phenylketonurias; Reference Values; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2011 |
Contributions of enriched cereal-grain products, ready-to-eat cereals, and supplements to folic acid and vitamin B-12 usual intake and folate and vitamin B-12 status in US children: National Health and Nutrition Examination Survey (NHANES), 2003-2006.
Topics: Adolescent; Child; Child, Preschool; Dietary Supplements; Edible Grain; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Infant; Male; Methylmalonic Acid; Nutrition Surveys; Time Factors; Vitamin B 12 | 2011 |
19-base pair deletion polymorphism of the dihydrofolate reductase (DHFR) gene: maternal risk of Down syndrome and folate metabolism.
Topics: Adolescent; Chi-Square Distribution; Child; Cross-Sectional Studies; Down Syndrome; Female; Folic Acid; Gene Frequency; Homocysteine; Humans; Methylmalonic Acid; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Factors; Tetrahydrofolate Dehydrogenase | 2010 |
Homocysteine is a determinant of ApoA-I and both are associated with ankle brachial index, in an ambulatory elderly population.
Topics: Age Factors; Aged; Aged, 80 and over; Ankle Brachial Index; Apolipoprotein A-I; Biomarkers; Cholesterol, HDL; Female; Folic Acid; Homocysteine; Humans; Independent Living; Male; Methylmalonic Acid; Middle Aged; Particle Size; Peripheral Arterial Disease; Regression Analysis; Risk Assessment; Risk Factors; Sicily; Vitamin B 12; Walking | 2011 |
Folate and cobalamin status in relation to diet in healthy 2-y-old children.
Topics: Child, Preschool; Dairy Products; Diet; Diet Records; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Methylmalonic Acid; Multivariate Analysis; Norway; Nutrition Policy; Nutritional Status; Transcobalamins; Vitamin B 12; Vitamin B Complex | 2011 |
Total blood mercury, plasma homocysteine, methylmalonic acid and folate in US children aged 3-5 years, NHANES 1999-2004.
Topics: Child, Preschool; Cross-Sectional Studies; Environmental Exposure; Environmental Pollutants; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Mercury; Methylmalonic Acid; Nutrition Surveys; United States | 2011 |
Inborn errors of cobalamin absorption and metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Anemia, Megaloblastic; Cobamides; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Malabsorption Syndromes; Metabolism, Inborn Errors; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Neonatal Screening; Proteinuria; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Vitamin B12 deficiency, hyperhomocysteinemia and thrombosis: a case and control study.
Topics: Adult; Aged; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Middle Aged; Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Diagnostic accuracy of holotranscobalamin, methylmalonic acid, serum cobalamin, and other indicators of tissue vitamin B₁₂ status in the elderly.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Discriminant Analysis; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Kidney Diseases; Kidney Function Tests; Linear Models; Male; Methylmalonic Acid; Middle Aged; Predictive Value of Tests; Reference Values; ROC Curve; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2011 |
The MMACHC proteome: hallmarks of functional cobalamin deficiency in humans.
Topics: Amino Acid Metabolism, Inborn Errors; Carrier Proteins; Cell Line; Cells, Cultured; Fibroblasts; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Intracellular Space; Metabolic Networks and Pathways; Methylmalonic Acid; Mutation; Oxidoreductases; Phenotype; Proteome; Vimentin; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2011 |
B-vitamin deficiency is protective against DSS-induced colitis in mice.
Topics: Analysis of Variance; Animals; Body Weight; Colitis; Dextran Sulfate; Gene Expression; Glutathione; Homocysteine; Inflammation; Interleukin-10; Kaplan-Meier Estimate; Male; Metabolomics; Methionine; Methylmalonic Acid; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Peroxidase; Pyridoxal Phosphate; S-Adenosylhomocysteine; Severity of Illness Index; Tumor Necrosis Factor-alpha; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2011 |
Do high blood folate concentrations exacerbate metabolic abnormalities in people with low vitamin B-12 status?
Topics: Adult; Cross-Sectional Studies; Female; Ferritins; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2011 |
Polymorphism C1420T of Serine hydroxymethyltransferase gene on maternal risk for Down syndrome.
Topics: DNA Primers; Down Syndrome; Female; Folic Acid; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Glycine Hydroxymethyltransferase; Homocysteine; Humans; Inheritance Patterns; Logistic Models; Methylmalonic Acid; Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors | 2012 |
Association of cognitive impairment with combinations of vitamin B₁₂-related parameters.
Topics: Aged; Biomarkers; Case-Control Studies; Cognition Disorders; Cross-Sectional Studies; Homocysteine; Humans; Methylmalonic Acid; Risk Assessment; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Uptake of cobalamin and markers of cobalamin status: a longitudinal study of healthy pregnant women.
Topics: Adult; Biomarkers; Denmark; Female; Homocysteine; Humans; Longitudinal Studies; Methylmalonic Acid; Pregnancy; Pregnancy Trimesters; Transcobalamins; Vitamin B 12 | 2011 |
Formate can differentiate between hyperhomocysteinemia due to impaired remethylation and impaired transsulfuration.
Topics: Animals; Biomarkers; Brain; Folic Acid Deficiency; Formates; Homocysteine; Hyperhomocysteinemia; Liver; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methionine; Methylation; Methylmalonic Acid; Models, Biological; Random Allocation; Rats; Rats, Sprague-Dawley; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2012 |
Total blood mercury and serum measles antibodies in US children, NHANES 2003-2004.
Topics: Antibodies, Viral; Child; Cross-Sectional Studies; Environmental Exposure; Environmental Pollutants; Female; Folic Acid; Homocysteine; Humans; Linear Models; Male; Measles; Measles virus; Mercury; Methylmalonic Acid; Nutrition Surveys; United States | 2011 |
Vitamin B₁₂ deficiency & cognitive impairment in elderly population.
Topics: Diet, Vegetarian; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Vitamin B₁₂ deficiency & levels of metabolites in an apparently normal urban south Indian elderly population.
Topics: Aged; Diet, Vegetarian; Erythrocytes; Female; Folic Acid; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; India; Male; Methylmalonic Acid; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Do we need to reconsider the desirable blood level of vitamin B12?
Topics: Age Factors; Homocysteine; Humans; Methylmalonic Acid; Prognosis; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Holotranscobalamin: not ready for prime time.
Topics: Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
[Approaches to vitamin B12 deficiency].
Topics: Adult; Aged; Anemia, Iron-Deficiency; Diagnostic Services; Diet, Vegetarian; Female; Homocysteine; Humans; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Methylmalonic acid and homocysteine assessment in the detection of vitamin B12 deficiency in patients with bilateral visual loss.
Topics: Adult; Aged, 80 and over; Blindness; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2012 |
Vision changes after spaceflight are related to alterations in folate- and vitamin B-12-dependent one-carbon metabolism.
Topics: Adult; Astronauts; Carbon Dioxide; Citrates; Cystathionine; Female; Folic Acid; Homocysteine; Humans; Male; Metabolic Networks and Pathways; Methylmalonic Acid; Middle Aged; Models, Biological; Refraction, Ocular; Space Flight; Vision Disorders; Vitamin B 12 | 2012 |
Methylation capacity in children with severe cerebral palsy.
Topics: Betaine; Biomarkers; Case-Control Studies; Cerebral Palsy; Child; Child, Preschool; Choline; Cystathionine; DNA Methylation; Erythrocyte Indices; Erythrocyte Membrane; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Queensland; Severity of Illness Index; Uric Acid | 2012 |
[Skin lesions induced by malnutrition in an infant with methylmalonic aciduria and homocysteic acidemia].
Topics: Homocysteine; Humans; Infant; Infant Nutrition Disorders; Male; Methylmalonic Acid; Skin Diseases; Vitamin B 12 | 2012 |
Cobalamin status in sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Black or African American; Cross-Sectional Studies; District of Columbia; Homocysteine; Hospitals, Teaching; Humans; Male; Methylmalonic Acid; Middle Aged; Nutritional Status; Prevalence; Prospective Studies; Renal Insufficiency, Chronic; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2013 |
Serum cobalamin, urine methylmalonic acid, and plasma total homocysteine concentrations in Border Collies and dogs of other breeds.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Biomarkers; Chromatography, Gas; Chromatography, High Pressure Liquid; Dog Diseases; Dogs; Female; Homocysteine; Luminescence; Male; Methylmalonic Acid; Reference Values; Species Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Genetic polymorphisms modulate the folate metabolism of Brazilian individuals with Down syndrome.
Topics: Adolescent; Adult; Brazil; Child; Child, Preschool; Chromosomes, Human, Pair 21; Down Syndrome; Female; Folic Acid; Gene Frequency; Genetic Association Studies; Genotype; Homocysteine; Humans; Infant; Linear Models; Male; Methylmalonic Acid; Polymorphism, Genetic; Sequence Analysis, DNA; Vitamin B 12 Deficiency; Young Adult | 2012 |
[Abnormal findings during newborn period of 160 patients with early-onset methylmalonic aciduria].
Topics: Amino Acid Metabolism, Inborn Errors; Carnitine; Child; Child, Preschool; China; Female; Folic Acid; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Male; Methylmalonic Acid; Neonatal Screening; Retrospective Studies; Vitamin B 12 | 2012 |
Maternal B vitamin status in pregnancy week 18 according to reported use of folic acid supplements.
Topics: Adult; Biomarkers; Dietary Supplements; Fatty Acids, Omega-3; Female; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methylmalonic Acid; Micronutrients; Norway; Pregnancy; Prospective Studies; Riboflavin; Socioeconomic Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2013 |
Total blood mercury and rubella antibody concentrations in US children aged 6-11 years, NHANES 2003-2004.
Topics: Antibodies, Viral; Child; Cross-Sectional Studies; Environmental Pollutants; Female; Folic Acid; Homocysteine; Humans; Immunoglobulin G; Linear Models; Male; Measles; Mercury; Methylmalonic Acid; Nutrition Surveys; United States; Vitamin B 12 | 2013 |
[Biological markers for the status of vitamins B12 and D: the importance of some analytical aspects in relation to clinical interpretation of results].
Topics: Biomarkers; Homocysteine; Humans; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D; Vitamin D Deficiency | 2012 |
Cognitive function in an elderly population: interaction between vitamin B12 status, depression, and apolipoprotein E ε4: the Hordaland Homocysteine Study.
Topics: Aged; Apolipoprotein E4; Cognition; Cognition Disorders; Cross-Sectional Studies; Depression; Female; Homocysteine; Humans; Linear Models; Male; Methylmalonic Acid; Neuropsychological Tests; Norway; Regression Analysis; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Vitamin B(12) intake and status in early pregnancy among urban South Indian women.
Topics: Adolescent; Adult; Anthropometry; Cross-Sectional Studies; Diet; Dietary Supplements; Erythrocytes; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; India; Methylmalonic Acid; Nutritional Status; Parity; Pregnancy; Prevalence; Socioeconomic Factors; Surveys and Questionnaires; Urban Population; Vitamin B 12; Vitamin B 12 Deficiency; White People; Young Adult | 2013 |
Detection of vitamin B12 deficiency in alcohol abuse.
Topics: Alcohol Abstinence; Alcoholism; Homocysteine; Humans; Methylmalonic Acid; Optic Atrophy, Hereditary, Leber; Smoking; Vision Disorders; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
DHFR 19-bp deletion and SHMT C1420T polymorphisms and metabolite concentrations of the folate pathway in individuals with Down syndrome.
Topics: Adolescent; Adult; Child; Child, Preschool; Down Syndrome; Female; Folic Acid; Gene Deletion; Gene Frequency; Genotype; Glycine Hydroxymethyltransferase; Homocysteine; Humans; Infant; Male; Methylmalonic Acid; Polymorphism, Genetic; Tetrahydrofolate Dehydrogenase; Young Adult | 2013 |
Serum homocysteine and methylmalonic acid concentrations in Chinese Shar-Pei dogs with cobalamin deficiency.
Topics: Animals; Dog Diseases; Dogs; Genetic Predisposition to Disease; Homocysteine; Methylmalonic Acid; Retrospective Studies; Vitamin B 12 Deficiency | 2013 |
Advanced age as a risk factor for folate-associated functional cobalamin deficiency.
Topics: Aged; Aged, 80 and over; Causality; Cognition Disorders; Comorbidity; Female; Folic Acid; Geriatric Assessment; Homocysteine; Humans; Male; Methylmalonic Acid; Risk Factors; Severity of Illness Index; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Problems related to the diagnosis of vitamin B12 deficiency optic neuropathy.
Topics: False Positive Reactions; Homocysteine; Humans; Methylmalonic Acid; Optic Nerve Diseases; Predictive Value of Tests; Reproducibility of Results; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Early biochemical and hematological response to intramuscular cyanocobalamin therapy in vitamin B(12)-deficient patients.
Topics: Aged; Chromatography, High Pressure Liquid; Cysteine; Erythrocyte Indices; Female; Folic Acid; Homocysteine; Humans; Injections, Intramuscular; Male; Methionine; Methylmalonic Acid; Middle Aged; Statistics, Nonparametric; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
A relationship between tube length and intraocular pressure after glaucoma drainage implant surgery cannot be explained by Poiseuille's law.
Topics: Female; Homocysteine; Humans; Male; Methylmalonic Acid; Vitamin B 12 Deficiency | 2014 |
Methylmalonic acid and homocysteine assessment in the detection of vitamin B12 deficiency in patients with bilateral visual loss - authors' reply.
Topics: Female; Homocysteine; Humans; Male; Methylmalonic Acid; Vitamin B 12 Deficiency | 2014 |
Role of serum holotranscobalamin (holoTC) in the diagnosis of patients with low serum cobalamin. Comparison with methylmalonic acid and homocysteine.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2014 |
A relationship between tube length and intra-ocular pressure after glaucoma drainage implant surgery cannot be explained by Poiseuille's law - author's reply.
Topics: Female; Homocysteine; Humans; Male; Methylmalonic Acid; Vitamin B 12 Deficiency | 2014 |
Adult-onset eculizumab-resistant hemolytic uremic syndrome associated with cobalamin C deficiency.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Antibodies, Monoclonal, Humanized; Betaine; Biopsy; Carrier Proteins; Diagnosis, Differential; Drug Resistance; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Hypertension, Malignant; Immunologic Factors; Kidney; Kidney Function Tests; Leucovorin; Lipotropic Agents; Male; Methionine; Methylmalonic Acid; Mutation; Oxidoreductases; Recurrence; Renal Dialysis; Treatment Outcome; Vitamin B 12 Deficiency; Vitamin B Complex | 2014 |
Vitamin B12 deficiency in relation to functional disabilities.
Topics: Activities of Daily Living; Aged; Biomarkers; Cognition; Disability Evaluation; Disabled Persons; Female; Geriatric Assessment; Homocysteine; Humans; Male; Methylmalonic Acid; Odds Ratio; Peripheral Nervous System Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Interactions between plasma concentrations of folate and markers of vitamin B(12) status with cognitive performance in elderly people not exposed to folic acid fortification: the Hordaland Health Study.
Topics: Aged; Biomarkers; Cognition Disorders; Cross-Sectional Studies; Diet; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methylmalonic Acid; Norway; Nutritional Status; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Plasma vitamin B12, methylmalonic acid and heart rate variability in healthy young Indian adults.
Topics: Adult; Heart Rate; Homocysteine; Humans; India; Male; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2013 |
Maternal vitamin B12 deficiency detected in expanded newborn screening.
Topics: Carnitine; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Neonatal Screening; Pregnancy; Pregnancy Complications; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Relationship between cobalamin-dependent metabolites and both serum albumin and alpha1 -proteinase inhibitor concentrations in hypocobalaminemic dogs of 7 different breeds.
Topics: alpha-Macroglobulins; Animals; Biomarkers; Breeding; Dog Diseases; Dogs; Female; Homocysteine; Male; Methylmalonic Acid; Serum Albumin; Species Specificity; Vitamin B 12 Deficiency | 2014 |
Reliable and powerful laboratory markers of cobalamin deficiency in the newborn: plasma and urinary methylmalonic acid.
Topics: Adult; Biomarkers; Cohort Studies; Female; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Pregnancy; Pregnancy Complications; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2016 |
A coumarin-based fluorescent probe as a central nervous system disease biomarker.
Topics: Biomarkers; Biosensing Techniques; Coumarins; Fluorescent Dyes; Homocysteine; Humans; Methylmalonic Acid; Parkinson Disease; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2014 |
Micronutrient status in female university students: iron, zinc, copper, selenium, vitamin B12 and folate.
Topics: Adolescent; Adult; Anemia, Iron-Deficiency; Australia; Biomarkers; Body Mass Index; Copper; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Iron, Dietary; Methylmalonic Acid; Micronutrients; Prevalence; Selenium; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult; Zinc | 2014 |
Suitability of methylmalonic acid and total homocysteine analysis in dried bloodspots.
Topics: Blood Specimen Collection; Chromatography, High Pressure Liquid; Dried Blood Spot Testing; Feasibility Studies; Homocysteine; Humans; Limit of Detection; Methylmalonic Acid; Plasma; Reproducibility of Results; Solvents; Tandem Mass Spectrometry | 2015 |
Functional cobalamin (vitamin B12) deficiency: role of advanced age and disorders associated with increased oxidative stress.
Topics: Aged; Aged, 80 and over; Aging; Alcohol Drinking; Connecticut; Diabetes Mellitus; Dietary Supplements; Female; Homocysteine; Humans; Injections, Intramuscular; Male; Methylmalonic Acid; Neurocognitive Disorders; Oxidative Stress; Primary Health Care; Renal Insufficiency; Retrospective Studies; Risk Factors; Smoking; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Serum folate, cobalamin, homocysteine and methylmalonic acid concentrations in pigs with acute, chronic or subclinical Lawsonia intracellularis infection.
Topics: Animals; Asymptomatic Infections; Desulfovibrionaceae Infections; Folic Acid; Homocysteine; Lawsonia Bacteria; Methylmalonic Acid; Swine; Swine Diseases; Vitamin B 12 | 2015 |
The influence of a whole food vegan diet with Nori algae and wild mushrooms on selected blood parameters.
Topics: Agaricales; Biomarkers; Blood Chemical Analysis; Cholecalciferol; Creatinine; Diet, Vegetarian; Dietary Supplements; Ergocalciferols; Ferritins; Folic Acid; Hemoglobins; Homocysteine; Humans; Meat; Methylmalonic Acid; Nutrition Assessment; Nutritional Status; Porphyra; Prospective Studies; Recommended Dietary Allowances; Thyrotropin; Time Factors; Transcobalamins; Vitamin B 12; Zinc | 2014 |
Vitamin B12-responsive neuropathies: A case series.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antioxidants; Biotransformation; Female; Homocysteine; Humans; Injections, Intramuscular; Male; Medical Records; Methylmalonic Acid; Middle Aged; Nervous System Diseases; Nutritional Status; Oxidative Stress; Retrospective Studies; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Combined indicator of vitamin B12 status: modification for missing biomarkers and folate status and recommendations for revised cut-points.
Topics: Biomarkers; Folic Acid; Healthy Volunteers; Homocysteine; Humans; Methylmalonic Acid; Transcobalamins; Vitamin B 12 | 2015 |
Comparison of four automated serum vitamin B12 assays.
Topics: Automation; Homocysteine; Humans; Immunoassay; Methylmalonic Acid; Regression Analysis; Vitamin B 12 | 2015 |
Pitfalls in the diagnostic evaluation of subacute combined degeneration.
Topics: Adult; Dietary Supplements; Homocysteine; Humans; Male; Methylmalonic Acid; Subacute Combined Degeneration; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2015 |
Vitamin B12 and folate levels in healthy Swiss senior citizens: a prospective study evaluating reference intervals and decision limits.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Biomarkers; Erythrocyte Count; Female; Folic Acid; Homocysteine; Humans; Kidney Function Tests; Male; Methylmalonic Acid; Middle Aged; Prospective Studies; Reference Values; ROC Curve; Sex Factors; Switzerland; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
[CME - laboratory 41. Evaluating vitamin B12 status].
Topics: Clinical Laboratory Techniques; Homocysteine; Humans; Methylmalonic Acid; Reference Values; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
B-vitamin status and bone mineral density and risk of lumbar osteoporosis in older females in the United States.
Topics: Absorptiometry, Photon; Aged; Biomarkers; Bone Density; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Nutrition Surveys; Nutritional Status; Osteoporosis; Risk Factors; United States; Vitamin B Complex | 2015 |
Low Cobalamin Levels as Predictors of Cobalamin Deficiency: Importance of Comorbidities Associated with Increased Oxidative Stress.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Comorbidity; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Oxidative Stress; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2016 |
False-normal vitamin B12 results in a patient with pernicious anaemia.
Topics: Anemia, Pernicious; Diagnostic Errors; False Positive Reactions; Female; Homocysteine; Humans; Immunoassay; Methylmalonic Acid; Middle Aged; Vitamin B 12 | 2015 |
Biochemical Identification of Vitamin B12 Deficiency in a Medical Office.
Topics: Ambulatory Care; Area Under Curve; Biomarkers; Cross-Sectional Studies; Early Diagnosis; Homocysteine; Humans; Immunoassay; Luminescent Measurements; Male; Methylmalonic Acid; Middle Aged; Office Visits; Predictive Value of Tests; ROC Curve; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Nutritional Supplementation with Chlorella pyrenoidosa Lowers Serum Methylmalonic Acid in Vegans and Vegetarians with a Suspected Vitamin B₁₂ Deficiency.
Topics: Adult; Biological Availability; Chlorella; Diet, Vegan; Diet, Vegetarian; Dietary Supplements; Hematocrit; Hemoglobins; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Vegans; Vegetarians; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2015 |
Laughing Gas in a Pediatric Emergency Department-Fun for All Participants: Vitamin B12 Status Among Medical Staff Working With Nitrous Oxide.
Topics: Adult; Anesthetics, Inhalation; Case-Control Studies; Cross-Sectional Studies; Emergency Service, Hospital; Female; Homocysteine; Humans; Male; Medical Staff; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Nitrous Oxide; Occupational Diseases; Occupational Exposure; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Evaluation of oxidant and antioxidant status in patients with vitamin B12 deficiency.
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Case-Control Studies; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Oxidants; Oxidative Stress; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Young Adult | 2015 |
Methylmalonic Acid and Homocysteine as Indicators of Vitamin B-12 Deficiency in Cancer.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cross-Sectional Studies; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Neoplasms; Prevalence; Vitamin B 12 Deficiency; Young Adult | 2016 |
Low Serum Vitamin B-12 Concentrations Are Prevalent in a Cohort of Pregnant Canadian Women.
Topics: Adult; Canada; Diet; Dietary Supplements; DNA Methylation; Female; Fetal Blood; Fetus; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Prevalence; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2016 |
Nutritional Intake and Status of Cobalamin and Folate among Non-Pregnant Women of Reproductive Age in Bhaktapur, Nepal.
Topics: Adolescent; Adult; Body Mass Index; Body Weight; Cross-Sectional Studies; Energy Intake; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Linear Models; Methylmalonic Acid; Nepal; Nutritional Status; Prevalence; Socioeconomic Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2016 |
Associations of Milk Consumption and Vitamin B₂ and Β
Topics: Adolescent; Animals; Anthropometry; Calcium, Dietary; Child; Child Development; Child Nutritional Physiological Phenomena; Cross-Sectional Studies; Diet; Female; Greece; Homocysteine; Humans; Male; Methylmalonic Acid; Milk; Physical Endurance; Physical Fitness; Regression Analysis; Riboflavin; Vitamin B 12; Zinc | 2016 |
A Prospective Study on Serum Methylmalonic Acid and Homocysteine in Pregnant Women.
Topics: Adult; Female; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Middle Aged; Pregnancy; Pregnancy Outcome; Prospective Studies; Republic of Korea; Young Adult | 2016 |
Rapid healing of a patient with dramatic subacute combined degeneration of spinal cord: a case report.
Topics: Antibodies; Gastrins; Gastroscopy; Homocysteine; Humans; Inflammation; Male; Methylmalonic Acid; Middle Aged; Parietal Cells, Gastric; Spinal Cord; Subacute Combined Degeneration; Transcobalamins; Vitamin B 12 Deficiency | 2017 |
Efficacy of early treatment in patients with cobalamin C disease identified by newborn screening: a 16-year experience.
Topics: Cohort Studies; Dietary Proteins; Female; Homocysteine; Humans; Infant; Infant, Newborn; Longitudinal Studies; Male; Methionine; Methylmalonic Acid; Neonatal Screening; Neurocognitive Disorders; Retrospective Studies; Secondary Prevention; Vitamin B 12 Deficiency | 2017 |
Vitamin B-12 status in infancy is positively associated with development and cognitive functioning 5 y later in Nepalese children.
Topics: Adult; Asia; Child Development; Cognition; Cognitive Dysfunction; Female; Homocysteine; Humans; Infant; Male; Methylmalonic Acid; Nepal; Neurodevelopmental Disorders; Neuropsychological Tests; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2017 |
An Adolescent with Increased Plasma Methylmalonic Acid and Total Homocysteine.
Topics: Adolescent; Homocysteine; Humans; Male; Methylmalonic Acid | 2017 |
Commentary.
Topics: Adolescent; Homocysteine; Humans; Methylmalonic Acid | 2017 |
Commentary.
Topics: Adolescent; Homocysteine; Humans; Methylmalonic Acid | 2017 |
A Black Cohosh Extract Causes Hematologic and Biochemical Changes Consistent with a Functional Cobalamin Deficiency in Female B6C3F1/N Mice.
Topics: Anemia, Megaloblastic; Animals; Body Weight; Cimicifuga; Female; Folic Acid; Homocysteine; Kidney; Liver; Methylmalonic Acid; Mice; Plant Extracts; Tetrahydrofolate Dehydrogenase; Vitamin B 12; Vitamin B 12 Deficiency | 2017 |
Serum methylmalonic acid correlates with neuropathic pain in idiopathic Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Biomarkers; Cross-Sectional Studies; Female; Homocysteine; Humans; Levodopa; Male; Methylmalonic Acid; Middle Aged; Neural Conduction; Neuralgia; Pain Measurement; Parkinson Disease; Prevalence; Severity of Illness Index; Vitamin B 12 | 2017 |
Folate and vitamin B12 status is associated with insulin resistance and metabolic syndrome in morbid obesity.
Topics: Adult; Body Mass Index; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Insulin Resistance; Male; Metabolic Syndrome; Methylmalonic Acid; Middle Aged; Obesity, Morbid; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Early changes in vitamin B12 uptake and biomarker status following Roux-en-Y gastric bypass and sleeve gastrectomy.
Topics: Adult; Aged; Avitaminosis; Biomarkers; Female; Gastrectomy; Gastric Bypass; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Obesity, Morbid; Postoperative Complications; Prospective Studies; Transcobalamins; Vitamin B 12 | 2019 |
Early pregnancy folate-cobalamin interactions and their effects on cobalamin status and hematologic variables throughout pregnancy.
Topics: Adult; Anemia, Iron-Deficiency; Body Mass Index; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Iron, Dietary; Longitudinal Studies; Methylmalonic Acid; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Prevalence; Socioeconomic Factors; Vitamin B 12 | 2018 |
Maternal and infant vitamin B12 status during infancy predict linear growth at 5 years.
Topics: Adolescent; Adult; Breast Feeding; Child, Preschool; Diet; Female; Folic Acid; Growth; Homocysteine; Humans; Infant; Lactation; Limit of Detection; Male; Methylmalonic Acid; Middle Aged; Nepal; Random Allocation; Vitamin B 12; Young Adult | 2018 |
Newborn screening for homocystinurias: Recent recommendations versus current practice.
Topics: Acetylcarnitine; Amino Acid Metabolism, Inborn Errors; Carnitine; Female; Glycine N-Methyltransferase; Homocysteine; Homocystinuria; Humans; Infant, Newborn; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Muscle Spasticity; Neonatal Screening; Phenylalanine; Psychotic Disorders | 2019 |
Methylmalonic Acid and Homocysteine as Indicators of Vitamin B12 Deficiency in Patients with Gastric Cancer after Gastrectomy.
Topics: Adult; Aged; Biomarkers; Female; Gastrectomy; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Postoperative Complications; Retrospective Studies; Stomach Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Homocysteine Metabolism in Children and Adolescents: Influence of Age on Plasma Biomarkers and Correspondent Genotype Interactions.
Topics: Adolescent; Age Factors; Biomarkers; Child; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Vitamin B 12; Vitamin B Complex | 2019 |
Week-to-week biological variation of methylmalonic acid and homocysteine in healthy women.
Topics: Adult; Biological Variation, Individual; Female; Health; Homocysteine; Humans; Methylmalonic Acid; Middle Aged | 2019 |
Investigating vitamin B12 deficiency.
Topics: Adult; Aged; Biomarkers; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Infant; Malabsorption Syndromes; Male; Malnutrition; Methylmalonic Acid; Physical Examination; Practice Guidelines as Topic; Pregnancy; Referral and Consultation; Risk Factors; United Kingdom; Vitamin B 12; Vitamin B 12 Deficiency; Vulnerable Populations | 2019 |
A genetic epidemiological study in British adults and older adults shows a high heritability of the combined indicator of vitamin B
Topics: Adult; Aged; Aged, 80 and over; Alkyl and Aryl Transferases; Biomarkers; Energy Metabolism; Female; Ferredoxin-NADP Reductase; Genome-Wide Association Study; Homocysteine; Humans; Male; Metabolism, Inborn Errors; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Middle Aged; Mitochondria; Molecular Epidemiology; Polymorphism, Single Nucleotide; Thiolester Hydrolases; Transcobalamins; Valine; Vitamin B 12 | 2019 |
Serum Vitamin B12 and Methylmalonic Acid Status in Migraineurs: A Case-Control Study.
Topics: Adolescent; Adult; Anthropometry; Case-Control Studies; Cost of Illness; Disease Progression; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Migraine Disorders; Nutritional Status; Pain Measurement; Social Class; Vitamin B 12; Young Adult | 2019 |
Isolated subacute combined degeneration in late-onset cobalamin C deficiency in children: Two case reports and literature review.
Topics: Adolescent; Ataxia; Brain; Carrier Proteins; Child; Female; Homocysteine; Homocystinuria; Humans; Injections, Intravenous; Late Onset Disorders; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Mutation; Oxidoreductases; Subacute Combined Degeneration; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2019 |
Assessment of cellular cobalamin metabolism in Gaucher disease.
Topics: beta-Glucosidase; Cell Culture Techniques; Female; Fibroblasts; Gaucher Disease; Glucosylceramidase; Homocysteine; Humans; Lysosomes; Male; Methylmalonic Acid; Mutation; Phenotype; Saposins; Transcobalamins; Vitamin B 12 | 2020 |
Normal serum cobalamin levels do not exclude the diagnosis of pernicious anaemia: a case report.
Topics: Anemia, Pernicious; Female; Folic Acid Deficiency; Gastritis, Atrophic; Homocysteine; Humans; Hydroxocobalamin; Methylmalonic Acid; Middle Aged; Tetrahydrofolates; Vitamin B 12; Vitamin B Complex | 2020 |
Diagnostic Accuracy of Holotranscobalamin, Vitamin B12, Methylmalonic Acid, and Homocysteine in Detecting B12 Deficiency in a Large, Mixed Patient Population.
Topics: Adult; Aged; Biomarkers; Cohort Studies; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Retrospective Studies; ROC Curve; Sensitivity and Specificity; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Assessment of folate and cobalamin concentrations in relation to their dependent intracellular metabolites in serum of pigs between 6 and 26 weeks of age.
Topics: Animals; Cytoplasm; Folic Acid; Homocysteine; Methylmalonic Acid; Serum; Sus scrofa; Vitamin B 12 | 2020 |
Functional vitamin B12 deficiency in phenylketonuria patients and healthy controls: An evaluation with combined indicator of vitamin B12 status as a biochemical index.
Topics: Adolescent; Biomarkers; Case-Control Studies; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Phenylketonurias; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Determination of methylmalonic acid, 2-methylcitric acid, and total homocysteine in dried blood spots by liquid chromatography-tandem mass spectrometry: A reliable follow-up method for propionylcarnitine-related disorders in newborn screening.
Topics: Carnitine; Chromatography, Liquid; Citrates; Follow-Up Studies; Homocysteine; Humans; Infant; Infant, Newborn; Methylmalonic Acid; Neonatal Screening; Prospective Studies; Retrospective Studies; Tandem Mass Spectrometry | 2021 |
Proteinuria as a presenting sign of combined methylmalonic acidemia and homocysteinemia: case report.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Base Sequence; Carnitine; Child, Preschool; DNA; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Proteinuria | 2020 |
Diagnostic Characteristics of 3-Parameter and 2-Parameter Equations for the Calculation of a Combined Indicator of Vitamin B12 Status to Predict Cobalamin Deficiency in a Large Mixed Patient Population.
Topics: Biomarkers; Homocysteine; Humans; Methylmalonic Acid; ROC Curve; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Test utilization for the diagnosis of vitamin B12 and folate deficiency in local clinics in Korea.
Topics: Adult; Anemia, Macrocytic; Blood Chemical Analysis; Erythrocyte Indices; Folic Acid; Folic Acid Deficiency; Hematologic Tests; Homocysteine; Humans; Methylmalonic Acid; Republic of Korea; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
The relationship between exacerbated diabetic peripheral neuropathy and metformin treatment in type 2 diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Homocysteine; Humans; Male; Metformin; Methylmalonic Acid; Middle Aged; Peripheral Nervous System Diseases; Risk Factors; Vitamin B 12 | 2021 |
A high frequency and geographical distribution of MMACHC R132* mutation in children with cobalamin C defect.
Topics: Adolescent; Child; Child, Preschool; Exons; Female; Homocysteine; Humans; India; Infant; Infant, Newborn; Male; Methylmalonic Acid; Oxidoreductases; Point Mutation; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
Cross-sectional association between vitamin B12 status and probable postpartum depression in Indian women.
Topics: Adolescent; Adult; Cesarean Section; Cross-Sectional Studies; Depression, Postpartum; Diet; Female; Homocysteine; Humans; India; Methylmalonic Acid; Pregnancy; Pregnancy, Unplanned; Risk Factors; S-Adenosylmethionine; Serotonin; Social Class; Tetrahydrofolates; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2021 |
Value of amniotic fluid homocysteine assay in prenatal diagnosis of combined methylmalonic acidemia and homocystinuria, cobalamin C type.
Topics: Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Female; Homocysteine; Homocystinuria; Humans; Methylmalonic Acid; Oxidoreductases; Pregnancy; Prenatal Diagnosis; Reproducibility of Results; Retrospective Studies; Vitamin B 12 | 2021 |
Cardiovascular manifestations of intermediate and major hyperhomocysteinemia due to vitamin B12 and folate deficiency and/or inherited disorders of one-carbon metabolism: a 3.5-year retrospective cross-sectional study of consecutive patients.
Topics: Adult; Cardiovascular Diseases; Child, Preschool; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Metabolism, Inborn Errors; Methylmalonic Acid; Middle Aged; Retrospective Studies; Vitamin B 12 | 2021 |
Implementation of second-tier tests in newborn screening for the detection of vitamin B
Topics: Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Neonatal Screening; Propionic Acidemia; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2021 |
The marker of cobalamin deficiency, plasma methylmalonic acid, may help identifying lysosomal iron trapping in patients. Its possible utility for heart failure.
Topics: Heart Failure; Homocysteine; Humans; Iron; Lysosomes; Methylmalonic Acid; Vitamin B 12 | 2021 |
Absence of MMACHC in peripheral retinal cells does not lead to an ocular phenotype in mice.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Metabolism, Inborn Errors; Animals; Female; Homocysteine; Homocystinuria; Humans; Male; Methylmalonic Acid; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Mutation; Oxidoreductases; Phenotype; Retina; Retinal Degeneration; Vitamin B 12; Young Adult | 2021 |
Clinical relevance of testing for metabolic vitamin B12 deficiency in patients with polyneuropathy.
Topics: Homocysteine; Humans; Methylmalonic Acid; Polyneuropathies; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
The roles of homocysteinemia and methylmalonic acidemia in kidney injury in atypical hemolytic uremic syndrome caused by cobalamin C deficiency.
Topics: Acute Kidney Injury; Amino Acid Metabolism, Inborn Errors; Atypical Hemolytic Uremic Syndrome; Female; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Kidney; Methylmalonic Acid; Oxidoreductases; Thrombotic Microangiopathies; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Vitamin B
Topics: Creatinine; Homocysteine; Humans; Methylmalonic Acid; Nitrous Oxide; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
Reference intervals for plasma vitamin B12 and plasma/serum methylmalonic acid in Danish children, adults and elderly.
Topics: Adult; Aged; Child; Denmark; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Reference Values; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Does Metformin Treatment in Pediatric Population Cause Vitamin B12 Deficiency?
Topics: Adolescent; Child; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Male; Metabolic Syndrome; Metformin; Methylmalonic Acid; Prospective Studies; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Vitamin B-12 malabsorption and renal function are critical considerations in studies of folate and vitamin B-12 interactions in cognitive performance: NHANES 2011-2014.
Topics: Aged; Cognition; Dietary Supplements; Folic Acid; Homocysteine; Humans; Kidney; Methylmalonic Acid; Nutrition Surveys; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
Pregnancy homocysteine and cobalamin status predict childhood metabolic health in the offspring.
Topics: Birth Weight; Child; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Pregnancy; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2023 |
Nitrous oxide in labour predicted newborn screening total homocysteine and is a potential risk factor for infant vitamin B12 deficiency.
Topics: Case-Control Studies; Homocysteine; Humans; Infant; Infant, Newborn; Methylmalonic Acid; Neonatal Screening; Nitrous Oxide; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Clinical characteristics and genotype analysis of five infants with cblX type of methylmalonic acidemia.
Topics: Acetylcarnitine; Amino Acid Metabolism, Inborn Errors; China; Drug Resistant Epilepsy; Female; Genotype; Homocysteine; Host Cell Factor C1; Humans; Infant; Infant, Newborn; Male; Methylmalonic Acid; Vitamin B 12 | 2022 |
Simultaneous estimation of total homocysteine and methylmalonic-acid using LC-MS/MS: Clinical application in adult and pediatric.
Topics: Adult; Biomarkers; Child; Chromatography, Liquid; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Pediatrics; Tandem Mass Spectrometry; Vitamin B 12 | 2022 |
Acquired Vitamin B12 Deficiency in Newborns: Positive Impact on Newborn Health through Early Detection.
Topics: Biomarkers; Early Diagnosis; Female; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant Health; Infant, Newborn; Male; Methylmalonic Acid; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
The association between methylmalonic acid, a biomarker of mitochondria dysfunction, and phenotypic age acceleration: A population-based study.
Topics: Aged; Biomarkers; Cross-Sectional Studies; Female; Homocysteine; Humans; Male; Methylmalonic Acid; Nutrition Surveys; Vitamin B 12; Vitamin B 12 Deficiency | 2024 |