homocysteine has been researched along with metformin in 59 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (6.78) | 18.2507 |
| 2000's | 21 (35.59) | 29.6817 |
| 2010's | 26 (44.07) | 24.3611 |
| 2020's | 8 (13.56) | 2.80 |
| Authors | Studies |
|---|---|
| Hoogeveen, EK; Stehouwer, CD | 1 |
| Bjerve, KS; Carlsen, SM; Følling, I; Grill, V; Refsum, H; Schneede, J | 1 |
| Bouter, LM; Heine, RJ; Hoogeveen, EK; Jakobs, C; Kostense, PJ; Stehouwer, CD | 1 |
| Aarsand, AK; Carlsen, SM | 1 |
| Buysschaert, M; Dramais, AS; Hermans, MP; Wallemacq, PE | 1 |
| Lavie, L; Levy, Y; Yeromenko, Y | 1 |
| Bicíková, M; Hill, M; Stárka, L; Tallová, J; Vrbíková, J | 1 |
| Andrès, E; Goichot, B; Noel, E | 1 |
| Brain, AM; Child, DF; Davies, GK; De, P; Harvey, JN; Hudson, PR; Jones, H; Mukherjee, S; Williams, CP | 1 |
| Ciccarelli, L; Derosa, G; Fogari, R; Franzetti, I; Gadaleta, G | 1 |
| Chattananon, A; Pongchaidecha, M; Srikusalanukul, V; Tanjariyaporn, S | 1 |
| Aslan, E; Bagis, T; Erkanli, S; Haydardedeoglu, B; Kilicdag, EB; Tarim, E; Zeyneloglu, HB | 1 |
| Aslan, E; Bagis, T; Erkanli, S; Haydardedeoglu, B; Kilicdag, EB; Kuscu, E; Simsek, E; Tarim, E | 1 |
| Diakoumopoulou, E; Doulgerakis, D; Katsilambros, N; Kirlaki, E; Kitsou, E; Perrea, D; Psallas, M; Tentolouris, N | 1 |
| Lefebvre, DL; Rosen, CF | 1 |
| Bets, D; Donker, AJ; Kooy, A; Lehert, P; Stehouwer, CD; Wulffelé, MG | 1 |
| Arslan, M; Ayvaz, G; Bukan, N; Cakir, N; Karakoç, A; Törüner, F; Yilmaz, M | 1 |
| Ciccarelli, L; Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Gravina, A; Montagna, L; Paniga, S; Piccinni, MN; Pricolo, F; Ragonesi, PD; Salvadeo, SA | 1 |
| Bouzid, C; Essais, O; Ibrahim, H; Machghoul, S; Ouertani, H; Ouni, Z; Zidi, B | 1 |
| Friedler, S; Raziel, A; Ron-El, R; Rotem, C; Schachter, M; Strassburger, D | 1 |
| Carlsen, SM; Kjøtrød, S; Romundstad, P; Vanky, E | 1 |
| Boaz, M; Fux, A; Gavish, D; Hanah, R; Mashavi, M; Matas, Z; Shargorodsky, M | 1 |
| Kalathil, D; Musarrat, K; Varughese, GI | 1 |
| del Rey Sánchez, JM; Escobar-Morreale, HF; Luque-Ramírez, M; Matíes, M; Mendieta-Azcona, C | 1 |
| Bagis, T; Haydardedeoglu, B; Kilicdag, EB; Simsek, E | 1 |
| Toth, C; Wile, DJ | 1 |
| Colao, A; Falbo, A; Giallauria, F; Orio, F; Palomba, S; Russo, T; Tolino, A; Zullo, F | 1 |
| Bets, D; de Jager, J; Donker, AJ; Kooy, A; Lehert, P; Stehouwer, CD; van der Kolk, J; Verburg, J; Wulffelé, MG | 1 |
| Chatzopoulos, S; Hatzitolios, A; Mikhailidis, D; Ntaios, G; Savopoulos, C | 1 |
| Aydin, M; Batioglu, S; Erdogan, G; Kilic, S; Yilmaz, N; Zulfikaroglu, E | 1 |
| Aghamohammadi, V; Aliasgharzadeh, A; Gargari, BP | 1 |
| Bitla, A; P V L N Rao, S; Rajagopal, G; Reddy, AP; Sachan, A; Suresh, V; Venkata Harinarayan, C | 1 |
| Cacciapuoti, F | 1 |
| Baghurst, PA; Coat, S; Gatford, KL; Hague, WM; Houda, CM; Lu, ZX; Owens, JA; Rowan, JA; Sikaris, K | 1 |
| Atamer, A; Atamer, Y; Can, AS; Hekimoğlu, A; Ilhan, N; Koçyiğit, Y; Yenice, N | 1 |
| Aizawa, T; Funase, Y; Ouchi, K; Sato, Y; Yamauchi, K | 1 |
| Brouwer-Brolsma, EM; de Groot, LC; de Jonge, R; Dhonukshe-Rutten, RA; Enneman, AW; Ham, AC; Lips, P; Oliai Araghi, S; Sohl, E; Stricker, BH; Swart, KM; Uitterlinden, AG; van der Cammen, TJ; van der Velde, N; van der Zwaluw, NL; van Dijk, SC; van Meurs, JB; van Schoor, NM; van Wijngaarden, JP; Witkamp, RF; Zillikens, MC | 1 |
| Gilowski, W; Krysiak, R; Okopien, B; Szkrobka, W | 1 |
| Alibrandi, A; Cucinotta, D; Forte, F; Gambadoro, N; Giandalia, A; Perdichizzi, G; Romeo, EL; Russo, GT; Scarcella, C; Zingale, R | 1 |
| Abd-Allah, GM; Hassan, MH | 1 |
| Gilowski, W; Krysiak, R; Okopien, B | 1 |
| Aroda, VR; Bray, GA; Crandall, JP; Edelstein, SL; Goldberg, RB; Knowler, WC; Marcovina, SM; Orchard, TJ; Schade, DS; Temprosa, MG; White, NH | 1 |
| Bucci, F; De Negri, F; Fruzzetti, F; Gadducci, A; Ghiadoni, L; Giannarelli, C; Perini, D; Taddei, S; Virdis, A | 1 |
| Behera, J; Jeremic, N; Majumder, A; Tyagi, SC | 1 |
| Bernstein, V; Brien, W; Chalchal, HI; Chen, BE; Gelmon, KA; Goodwin, PJ; Hershman, DL; Hobday, TJ; Lemieux, J; Liebman, MF; Ligibel, JA; Lohmann, AE; Mayer, IA; Mukherjee, SD; Parulekar, WR; Pritchard, KI; Rastogi, P; Shepherd, LE; Stambolic, V; Thompson, AM; Whelan, TJ | 1 |
| Cheung, KWK; Giacomini, KM; Hsueh, CH; Huang, SM; Meyer, TW; Zhang, L; Zhao, P | 1 |
| Breitenstein, MK; Cairns, J; Caraballo, PJ; Moore, JH; Olson, RS; Orlenko, A; Orzechowski, P; Wang, L; Weinshilboum, RM | 1 |
| Borowska, M; Dworacka, M; Krzyżagórska, E; Winiarska, H | 1 |
| Bodur, S; Dundar, O; Kanat-Pektas, M; Kinci, MF; Tutuncu, L | 1 |
| Miller, JW | 1 |
| Ahn, CW; Fang, S; Kim, J; Lee, HS; Park, JS | 1 |
| Hirota, Y; Ogawa, W; Okada, Y; Sakaguchi, K; Sugawara, K | 1 |
| Bayrak, BB; Karabulut Bulan, O; Koroglu, P; Yanardag, R | 1 |
| El-Sherif, M; Esmael, A; Hashem, MM; Nassar, AK | 1 |
| Bai, Y; Fang, Z; Li, X; Pan, H; Wang, F; Yang, X; Zhang, C | 1 |
| Al-Dhabi, NA; Arasu, MV; Arockiaraj, J; C, M; Chatterjee, S; Choi, KC; Karuppiah, K; Natarajan, S; Raj, V; Ramanujam, GM; Ramasamy, M | 1 |
| Berberoglu, M; Dogan, O; Eminoglu, FT; Kontbay, T; Kose, E; Siklar, Z; Taş, Ö; Tumer, L | 1 |
| Lauren, BC; Pratama, S; Wisnu, W | 1 |
| Chen, M; Huang, W; Kang, Z; Li, Q; Liu, T; Shu, Y; Zhang, W; Zhou, H | 1 |
6 review(s) available for homocysteine and metformin
| Article | Year |
|---|---|
Homocysteine and cardiovascular risk in patients with diabetes mellitus.
Topics: Coronary Disease; Diabetes Complications; Diabetes Mellitus; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Metformin; Risk Factors; Vitamin B Complex | 2001 |
Iatrogenic hyperhomocysteinemia in patients with metabolic syndrome: a systematic review and metaanalysis.
Topics: Administration, Oral; Aged; Antihypertensive Agents; Clinical Trials as Topic; Fibric Acids; Homocysteine; Humans; Hydrochlorothiazide; Hyperhomocysteinemia; Hyperlipidemias; Hypoglycemia; Iatrogenic Disease; Metabolic Syndrome; Metformin; Middle Aged | 2011 |
Hypermethylation: Causes and Consequences in Skeletal Muscle Myopathy.
Topics: Animals; DNA Methylation; Epigenesis, Genetic; Folic Acid; Histones; Homocysteine; Humans; Hyperhomocysteinemia; Metformin; Muscle, Skeletal; Muscular Diseases; Oxidative Stress; RNA Interference; Thiazolidinediones; Vitamin B 12; Vitamin B 6 | 2017 |
Proton Pump Inhibitors, H2-Receptor Antagonists, Metformin, and Vitamin B-12 Deficiency: Clinical Implications.
Topics: Histamine H2 Antagonists; Homocysteine; Humans; Metformin; Methylmalonic Acid; Nutritional Status; Proton Pump Inhibitors; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
The effect of metformin on homocysteine levels in patients with polycystic ovary syndrome: A systematic review and meta-analysis.
Topics: Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome | 2021 |
The efficacy of vitamin B
Topics: Diabetes Mellitus, Type 2; Dietary Supplements; Homocysteine; Humans; Hypoglycemic Agents; Metformin; Peripheral Nervous System Diseases; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
25 trial(s) available for homocysteine and metformin
| Article | Year |
|---|---|
Metformin increases total serum homocysteine levels in non-diabetic male patients with coronary heart disease.
Topics: Adult; Coronary Disease; Cysteine; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Methylmalonic Acid; Middle Aged; Vitamin B 12 | 1997 |
Folate administration reduces circulating homocysteine levels in NIDDM patients on long-term metformin treatment.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dipeptides; Double-Blind Method; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Prospective Studies; Risk Factors; Time Factors; Treatment Outcome; Vitamin B 12 | 1998 |
The effect of oral folic acid on glutathione, glycaemia and lipids in Type 2 diabetes.
Topics: Adult; Aged; Albuminuria; Blood Glucose; Blood Pressure; Cholesterol, HDL; Diabetes Mellitus, Type 2; Dietary Supplements; Erythrocytes; Female; Folic Acid; Glutathione; Glycated Hemoglobin; Homocysteine; Humans; Hypoglycemic Agents; Lipids; Male; Metformin; Middle Aged; Triglycerides; Vitamin B 6 | 2004 |
Metabolic variations with oral antidiabetic drugs in patients with Type 2 diabetes: comparison between glimepiride and metformin.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Food; Glycated Hemoglobin; Homocysteine; Humans; Hypoglycemic Agents; Lipoprotein(a); Male; Metformin; Middle Aged; Plasminogen Activator Inhibitor 1; Sulfonylurea Compounds | 2004 |
Homocysteine levels in women with polycystic ovary syndrome treated with metformin versus rosiglitazone: a randomized study.
Topics: Adult; Anovulation; Blood Glucose; Body Weight; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Insulin Resistance; Lipids; Luteinizing Hormone; Metformin; Polycystic Ovary Syndrome; Rosiglitazone; Testosterone; Thiazolidinediones; Vitamin B 12 | 2005 |
Administration of B-group vitamins reduces circulating homocysteine in polycystic ovarian syndrome patients treated with metformin: a randomized trial.
Topics: Adolescent; Adult; Blood Glucose; Body Weight; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Lipids; Menstrual Cycle; Metformin; Ovulation; Polycystic Ovary Syndrome; Vitamin B Complex | 2005 |
Does metformin decrease blood pressure in patients with Type 2 diabetes intensively treated with insulin?
Topics: Age Factors; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Body Mass Index; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Female; Glycated Hemoglobin; Heart Rate; Homocysteine; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Time Factors | 2005 |
The effects of rosiglitazone and metformin on oxidative stress and homocysteine levels in lean patients with polycystic ovary syndrome.
Topics: Adult; Androgens; Antioxidants; Blood Glucose; Body Mass Index; Body Weight; Female; Homeostasis; Homocysteine; Humans; Hypoglycemic Agents; Insulin Resistance; Lipids; Malondialdehyde; Metformin; Models, Statistical; Oxidative Stress; Polycystic Ovary Syndrome; Risk Factors; Rosiglitazone; Smoking; Thiazolidinediones; Time Factors | 2005 |
Metformin-pioglitazone and metformin-rosiglitazone effects on non-conventional cardiovascular risk factors plasma level in type 2 diabetic patients with metabolic syndrome.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glycated Hemoglobin; Homocysteine; Humans; Hypoglycemic Agents; Insulin; Male; Metabolic Syndrome; Metformin; Middle Aged; Pioglitazone; Rosiglitazone; Thiazolidinediones | 2006 |
Prospective, randomized trial of metformin and vitamins for the reduction of plasma homocysteine in insulin-resistant polycystic ovary syndrome.
Topics: Adult; Female; Homocysteine; Humans; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Prospective Studies; Vitamins | 2007 |
Homocysteine levels are unaffected by metformin treatment in both nonpregnant and pregnant women with polycystic ovary syndrome.
Topics: Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Metformin; Methylenetetrahydrofolate Reductase (NADPH2); Polycystic Ovary Syndrome; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Prospective Studies; Testosterone; Vitamin B 12 | 2007 |
Effect of homocysteine-lowering therapy on arterial elasticity and metabolic parameters in metformin-treated diabetic patients.
Topics: Aged; Arteries; Diabetes Mellitus; Double-Blind Method; Elasticity; Female; Hemodynamics; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Placebos; Risk Factors | 2008 |
Effects of an antiandrogenic oral contraceptive pill compared with metformin on blood coagulation tests and endothelial function in women with the polycystic ovary syndrome: influence of obesity and smoking.
Topics: Adult; Androgen Antagonists; Blood Coagulation; Blood Platelets; Case-Control Studies; Contraceptives, Oral, Hormonal; Cyproterone Acetate; Drug Combinations; Endothelium, Vascular; Ethinyl Estradiol; Female; Fibrinogen; Homocysteine; Humans; Hypoglycemic Agents; Metformin; Obesity; Partial Thromboplastin Time; Polycystic Ovary Syndrome; Prothrombin; Smoking; Young Adult | 2009 |
Metabolic and endocrine effects of metformin and metformin plus cyclic medroxyprogesterone acetate in women with polycystic ovary syndrome.
Topics: Adolescent; Adult; Body Mass Index; Cholesterol; Contraceptive Agents, Female; Drug Therapy, Combination; Female; Follow-Up Studies; Homeostasis; Homocysteine; Humans; Hypoglycemic Agents; Insulin Resistance; Medroxyprogesterone Acetate; Metformin; Polycystic Ovary Syndrome; Prospective Studies; Young Adult | 2009 |
Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: randomised placebo controlled trial.
Topics: Aged; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Long-Term Care; Male; Metformin; Middle Aged; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2010 |
Inflammatory-metabolic parameters in obese and nonobese normoandrogenemic polycystic ovary syndrome during metformin and oral contraceptive treatment.
Topics: Adult; Arginine; Body Mass Index; Cardiovascular Diseases; Contraceptives, Oral; Female; Homocysteine; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Obesity; Polycystic Ovary Syndrome; Prospective Studies; Risk Factors; Young Adult | 2011 |
Effect of folic acid supplementation on homocysteine, serum total antioxidant capacity, and malondialdehyde in patients with type 2 diabetes mellitus.
Topics: Administration, Oral; Aged; Antioxidants; Diabetes Mellitus, Type 2; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Folic Acid; Homocysteine; Humans; Male; Malondialdehyde; Metformin; Middle Aged; Oxidative Stress; Vitamin B 12 | 2011 |
Vitamin B12 and homocysteine status during pregnancy in the metformin in gestational diabetes trial: responses to maternal metformin compared with insulin treatment.
Topics: Adult; Biomarkers; Cohort Studies; Diabetes, Gestational; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Metformin; Nutritional Status; Postpartum Period; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Pregnancy Trimester, Third; South Australia; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Effects of rosiglitazone on serum paraoxonase activity and metabolic parameters in patients with type 2 diabetes mellitus.
Topics: Aged; Aryldialkylphosphatase; Biomarkers; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Homocysteine; Humans; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Metabolome; Metformin; Middle Aged; Rosiglitazone; Sulfonylurea Compounds; Thiazolidinediones; Triglycerides | 2013 |
The Effect of Atorvastatin on Cardiometabolic Risk Factors in Bromocriptine-Treated Premenopausal Women with Isolated Hypercholesterolemia.
Topics: Adult; Atorvastatin; Bromocriptine; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diet; Dopamine Agonists; Exercise; Female; Fibrinogen; Homocysteine; Humans; Hypercholesterolemia; Hyperprolactinemia; Hypoglycemic Agents; Hypolipidemic Agents; Metformin; Middle Aged; Premenopause; Risk Factors; Uric Acid | 2015 |
Effects of metformin plus gliclazide versus metformin plus glimepiride on cardiovascular risk factors in patients with type 2 diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Folic Acid; Gliclazide; Glycated Hemoglobin; Homocysteine; Humans; Hypoglycemic Agents; Lipids; Male; Metformin; Middle Aged; Risk Factors; Sulfonylurea Compounds | 2015 |
Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study.
Topics: Adult; Aged; Anemia; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Effects of metformin versus placebo on vitamin B12 metabolism in non-diabetic breast cancer patients in CCTG MA.32.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Female; Homocysteine; Humans; Metformin; Methylmalonic Acid; Middle Aged; Treatment Outcome; Vitamin B 12 | 2017 |
Homocysteine as a non-classical risk factor for atherosclerosis in relation to pharmacotherapy of type 2 diabetes mellitus.
Topics: Aged; Aged, 80 and over; Atherosclerosis; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Risk Factors; Waist Circumference | 2017 |
The effects of different therapeutic modalities on cardiovascular risk factors in women with polycystıc ovary syndrome: A randomızed controlled study.
Topics: Adult; Androstenes; Apolipoproteins B; Blood Glucose; C-Reactive Protein; Cardiovascular Diseases; Drug Therapy, Combination; Ethinyl Estradiol; Female; Homocysteine; Humans; Hypoglycemic Agents; Insulin Resistance; Metabolic Syndrome; Metformin; Mineralocorticoid Receptor Antagonists; Peptide Fragments; Plasminogen Activator Inhibitor 1; Polycystic Ovary Syndrome; Reproductive Control Agents; Risk Factors; Young Adult | 2018 |
28 other study(ies) available for homocysteine and metformin
| Article | Year |
|---|---|
Should metformin be used to improve blood lipid pattern in nondiabetic patients with coronary heart disease?
Topics: Coronary Disease; Homocysteine; Humans; Hypoglycemic Agents; Lipids; Metformin; Risk Factors | 1996 |
Does metformin increase the serum total homocysteine level in non-insulin-dependent diabetes mellitus?
Topics: Adult; Aged; Arteriosclerosis; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Risk Factors | 1997 |
Hyperhomocysteinemia in type 2 diabetes: relationship to macroangiopathy, nephropathy, and insulin resistance.
Topics: Aged; Cohort Studies; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Female; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Logistic Models; Male; Metabolic Clearance Rate; Metformin; Middle Aged; Vitamin B 12 | 2000 |
Homocysteine and steroids levels in metformin treated women with polycystic ovary syndrome.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Blood Glucose; Body Constitution; Body Mass Index; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Homocysteine; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Metformin; Polycystic Ovary Syndrome; Pregnanolone; Steroids | 2002 |
Metformin-associated vitamin B12 deficiency.
Topics: Aged; Aged, 80 and over; Female; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Vitamin B 12 Deficiency | 2002 |
Effect of metformin on plasma homocysteine, vitamin B12 and folic acid: a cross-sectional study in patients with type 2 diabetes mellitus.
Topics: Adult; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Vitamin B 12 | 2004 |
Plasma homocysteine levels in patients with type 2 diabetes in a Mediterranean population: relation with nutritional and other factors.
Topics: Adult; Aged; Alcohol Drinking; Animals; Blood Glucose; Blood Pressure; Coffee; Diabetes Mellitus, Type 2; Diet; Exercise; Female; Fishes; Folic Acid; Fruit; Glomerular Filtration Rate; Glycated Hemoglobin; Homocysteine; Humans; Linear Models; Male; Meat; Mediterranean Region; Metformin; Middle Aged; Nutritional Status; Surveys and Questionnaires; Triglycerides; Vegetables | 2005 |
Regulation of SNARK activity in response to cellular stresses.
Topics: Adenosine Monophosphate; Animals; Cells, Cultured; Cricetinae; Dithiothreitol; Endoplasmic Reticulum; Gene Expression; Gene Expression Regulation; Glucose; Glutamine; Homocysteine; Humans; Hypertonic Solutions; Metformin; Osmotic Pressure; Oxidative Stress; Protein Serine-Threonine Kinases; Rats; Tissue Distribution; Ultraviolet Rays | 2005 |
[Factors influencing homocysteineamia in type 2 diabetic patients].
Topics: Diabetes Mellitus, Type 2; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Male; Metformin; Middle Aged; Obesity; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Metformin, B12 and homocysteine levels: the plausible cause or effect?
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Metformin; Venous Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Association of metformin, elevated homocysteine, and methylmalonic acid levels and clinically worsened diabetic peripheral neuropathy.
Topics: Aged; Case-Control Studies; Chromatography, High Pressure Liquid; Diabetic Neuropathies; Electrophysiology; Female; Homocysteine; Humans; Hypoglycemic Agents; Immunoassay; Male; Mass Spectrometry; Metformin; Methylmalonic Acid; Middle Aged; Peripheral Nervous System Diseases; Prospective Studies; Vitamin B 12 | 2010 |
Effects of metformin with or without supplementation with folate on homocysteine levels and vascular endothelium of women with polycystic ovary syndrome.
Topics: Adult; Body Mass Index; Brachial Artery; Double-Blind Method; Endothelin-1; Endothelium, Vascular; Exercise; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Leisure Activities; Metformin; Placebos; Polycystic Ovary Syndrome; Tunica Intima; Tunica Media; Vasodilation; Vitamin B 12; Waist-Hip Ratio | 2010 |
Effect of lifestyle modification and metformin therapy on emerging cardiovascular risk factors in overweight Indian women with polycystic ovary syndrome.
Topics: Adolescent; Adult; C-Reactive Protein; Cardiovascular Diseases; Female; Homeostasis; Homocysteine; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Life Style; Lipids; Maximum Tolerated Dose; Metformin; Overweight; Polycystic Ovary Syndrome; Radioimmunoassay; Risk Factors | 2012 |
Lowering homocysteine levels may prevent cardiovascular impairments? Possible therapeutic behaviors.
Topics: Acetylcysteine; Aspirin; Blood Vessels; Cardiovascular Diseases; Clopidogrel; Diuretics; Fatty Acids, Omega-3; Folic Acid; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Platelet Aggregation Inhibitors; S-Adenosylmethionine; Ticlopidine; Vitamin B 12; Vitamin B 6 | 2012 |
Relationship between metformin use, vitamin B12 deficiency, hyperhomocysteinemia and vascular complications in patients with type 2 diabetes.
Topics: Aged; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Retinopathy; Dietary Supplements; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Japan; Male; Metformin; Middle Aged; Prevalence; Risk Factors; Severity of Illness Index; Stroke; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Associations between medication use and homocysteine levels in an older population, and potential mediation by vitamin B12 and folate: data from the B-PROOF Study.
Topics: Aged; Diuretics; Female; Folic Acid; Health Services for the Aged; Homocysteine; Humans; Male; Metformin; Netherlands; Osteoporosis; Population Surveillance; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Diabetic neuropathy is not associated with homocysteine, folate, vitamin B12 levels, and MTHFR C677T mutation in type 2 diabetic outpatients taking metformin.
Topics: Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Folic Acid; Follow-Up Studies; Genotype; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Outpatients; Prognosis; Vitamin B 12 | 2016 |
The Effect of Metformin and Metformin-Testosterone Combination on Cardiometabolic Risk Factors in Men with Late-onset Hypogonadism and Impaired Glucose Tolerance.
Topics: Aged; C-Reactive Protein; Cholesterol, LDL; Eunuchism; Fibrinogen; Glucose Tolerance Test; Homocysteine; Humans; Male; Metformin; Middle Aged; Risk Factors; Testosterone; Uric Acid | 2015 |
Adolescents with Classical Polycystic Ovary Syndrome Have Alterations in the Surrogate Markers of Cardiovascular Disease but Not in the Endothelial Function. The Possible Benefits of Metformin.
Topics: Adolescent; Adult; Biomarkers; Blood Glucose; C-Reactive Protein; Cardiovascular Diseases; Carotid Intima-Media Thickness; Case-Control Studies; Endothelium; Female; Homocysteine; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Metformin; Plasminogen Activator Inhibitor 1; Polycystic Ovary Syndrome; Pulse Wave Analysis; Risk Factors; Tissue Plasminogen Activator | 2016 |
The Effect of Uremic Solutes on the Organic Cation Transporter 2.
Topics: Biological Transport; Dimethylamines; Glomerular Filtration Rate; Glucuronates; Glutathione Disulfide; HEK293 Cells; Homocysteine; Humans; Indoles; Kidney; Malondialdehyde; Metformin; Methylamines; Organic Cation Transporter 2; Renal Insufficiency, Chronic; Toxins, Biological; Uremia | 2017 |
Considerations for automated machine learning in clinical metabolic profiling: Altered homocysteine plasma concentration associated with metformin exposure.
Topics: Bias; Body Mass Index; Case-Control Studies; Computational Biology; Diabetes Mellitus, Type 2; Homocysteine; Humans; Hypoglycemic Agents; Metabolome; Metabolomics; Metformin; Risk Factors; Supervised Machine Learning; Translational Research, Biomedical | 2018 |
Association between metformin dose and vitamin B12 deficiency in patients with type 2 diabetes.
Topics: Age Factors; Aged; Alcohol Drinking; Anemia; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Odds Ratio; Republic of Korea; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2019 |
Relationship between metformin use and vitamin B
Topics: Aged; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Erythrocyte Indices; Female; Hemoglobins; Homocysteine; Humans; Hypoglycemic Agents; Japan; Male; Metformin; Middle Aged; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Metformin protects against diabetes-induced heart injury and dunning prostate cancer model.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Diabetes Mellitus, Experimental; Glutathione; Heart Injuries; Homocysteine; Lipid Peroxidation; Male; Metformin; Myocardium; Nitric Oxide; Oxidoreductases; Prostatic Neoplasms; Rats; Reactive Oxygen Species | 2021 |
The relationship between exacerbated diabetic peripheral neuropathy and metformin treatment in type 2 diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Homocysteine; Humans; Male; Metformin; Methylmalonic Acid; Middle Aged; Peripheral Nervous System Diseases; Risk Factors; Vitamin B 12 | 2021 |
Cholecalciferol and metformin protect against lipopolysaccharide-induced endothelial dysfunction and senescence by modulating sirtuin-1 and protein arginine methyltransferase-1.
Topics: Antioxidants; Arginine; Cell Cycle Checkpoints; Cell Line; Cellular Senescence; Cholecalciferol; Endothelium; Homocysteine; Humans; Lipopolysaccharides; Metformin; Methylation; NAD; Nitric Oxide; Protective Agents; Protein-Arginine N-Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Sirtuin 1; Telomerase; Vitamin D Response Element | 2021 |
Does Metformin Treatment in Pediatric Population Cause Vitamin B12 Deficiency?
Topics: Adolescent; Child; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Male; Metabolic Syndrome; Metformin; Methylmalonic Acid; Prospective Studies; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Bacteroides ovatus accelerates metformin-induced vitamin B12 deficiency in type 2 diabetes patients by accumulating cobalamin.
Topics: Animals; Diabetes Mellitus, Type 2; Homocysteine; Humans; Metformin; Mice; Vitamin B 12; Vitamin B 12 Deficiency | 2023 |