homocysteine and lysine

homocysteine has been researched along with lysine in 68 studies

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-199015 (22.06)18.7374
1990's3 (4.41)18.2507
2000's24 (35.29)29.6817
2010's23 (33.82)24.3611
2020's3 (4.41)2.80

Authors

AuthorsStudies
Fast, W; Hong, L1
Ardouin, P; Cartigny, B; Dhondt, JL; Farriaux, JP1
Colanduoni, J; Nissan, R; Villafranca, JJ1
Busiello, V; Cini, C; Coccia, R; Di Girolamo, A; Di Girolamo, M1
Baxter, CS; Byvoet, P1
Amos, HE; Digenis, GA; Little, CO; Mitchell, GE; Schelling, GT; Tucker, RE1
Century, B; Natelson, S; Vorkink, WP1
Hogenkamp, HP1
Crawhall, JC; Watts, RW1
Charpentier, C; Lemonnier, A; Levillain, P; Moatti, N1
Copeland, W; Kelly, S; Leikhim, E1
Shapshak, P1
Barnard, EA; Glick, DM; Goren, HJ1
Barnard, EA; Shall, S1
Hope, DB; Horncastle, KC1
Ferguson, E; Joseph, J; Kalyanaraman, B; Parthasarathy, S1
Hoover-Plow, J; Skocir, P1
Carroll, KK; Freeman, DJ; Giroux, I; Kurowska, EM1
Bakhtiar, R; Hop, CE1
Busch, M; Franke, S; Kientsch-Engel, R; Müller, A; Sommer, M; Stein, G1
Blazícek, P; Dzúrik, R; Gazdíková, K; Heidland, A; Schinzel, R; Sebeková, K; Spustová, V; Syrová, D1
Braun, A; Busch, M; Fleck, C; Franke, S; Müller, A; Müller, UA; Schiel, R; Stein, G1
BOYCE, WH; KING, JS1
Hishida, A; Kato, A; Odamaki, M1
Glowacki, R; Jakubowski, H1
Busch, M; Franke, C; Franke, S; Klemm, A; Lang, D; Müller, A; Passlick-Deetjen, J; Stein, G1
Jakubowski, H; Kaźmierski, R; Lacinski, M; Perła, J; Trzeciak, W; Undas, A1
Benner, J; Chin, HG; Estève, PO; Jacobsen, SE; Patnaik, D; Pradhan, S1
Cacciapuoti, G; Concilio, L; Forte, S; Graziano, G; Merlino, A; Moretti, MA; Porcelli, M1
Hoffman, M; Lenkowski, A; Lockhart, E; Sauls, DL; Warren, ME; Wilhelm, SE1
Fujii, K; Saito, M; Soshi, S; Tanaka, T1
Jakubowski, H1
Baragetti, I; Buccianti, G; Catapano, AL; Furiani, S; Galli, F; Maggi, FM; Raselli, S; Vettoretti, S1
Bárány, P; Heimbürger, O; Jogestrand, T; Lindholm, B; Maruyama, Y; Qureshi, AR; Stenvinkel, P; Suliman, ME1
Jakubowski, H; Kaján, L; Marczak, Ł; Perła-Kaján, J; Skowronek, P; Twardowski, T1
Kim, Y; Lee, HS; Lee, JY; Park, SD; Sim, SY1
Takeuchi, Y1
do Nascimento, MM; Hayashi, SY; Lindholm, B; Manfro, RC; Pachaly, MA; Riella, MC; Stenvinkel, P; Suliman, ME1
Gerasimova, YV; Godovikova, TS; Knorre, DD; Shakirov, MM1
Saito, M3
Escobedo, JO; Lim, S; Samoei, GK; Sibrian-Vazquez, M; Strongin, RM1
Higuchi, T; Kuroda, T; Saito, M; Shiraki, M; Shiraki, Y; Tanaka, S1
Marumo, K; Saito, M1
Jakubowski, H; Marczak, L; Sikora, M; Stobiecki, M; Twardowski, T1
Malinowska, J; Nowak, P; Olas, B1
Jakubowski, H; Marczak, L; Sikora, M; Stobiecki, M1
Suzuki, A1
Goto, M; Iwaki-Egawa, S; Watanabe, Y1
Kuroda, T; Saito, M; Shiraki, M; Shiraki, Y; Tanaka, S1
Castañon, M; Genoud, V; Lauricella, AM; Quintana, I1
Asriyantz, RA; Gaillard, C; Haertlé, T; Muronetz, VI; Semenyuk, PI; Stroylova, YY1
Nowak, P; Tadeusiewicz, J1
Hou, FF; Lei, W; Li, S; Liu, Z; Long, Y; Nie, J; Zhu, F1
Arru, D; Carru, C; Cossu, A; Giordo, R; Mangoni, AA; Pintus, G; Posadino, AM; Scanu, B; Sotgia, S; Zinellu, A1
Yamauchi, M1
Hatakeyama, Y; Kasukawa, Y; Miyakoshi, N; Miyamoto, S; Narita, Y; Sasaki, K; Senma, S; Shimada, Y; Tsuchie, H1
Jakubowski, H; Malinowska, A; Perła-Kajan, J; Rusek, M; Sitkiewicz, E; Utyro, O1
He, XD; Huang, L; Li, Y; Mei, XY; Nie, J; Qi, DS; Si, W; Zhao, SM1
Singh, SA; Srinivasan, K; Venkatesh, R1
Abe, K; Aoki, Y; Eguchi, Y; Fujimoto, K; Furuya, T; Inage, K; Kanamoto, H; Koda, M; Norimoto, M; Ohtori, S; Orita, S; Suzuki, M; Takahashi, K; Toyoguchi, T; Umimura, T; Yamauchi, K1
Chamorro, ME; Maltaneri, RE; Nesse, AB; Schiappacasse, A; Vittori, DC; Wetzler, DE1
Chen, C; Chen, YM; Li, Y; Lin, Y; Mei, XY; Qu, YY; Wang, D; Xu, W; Yang, SB; Zhang, X; Zhao, JY; Zhao, R; Zhao, SM; Zhou, Q; Zuo, ZG1
Jakubowski, H; Marczak, Ł; Perła-Kajan, J; Sikora, M1
Cysewski, D; Jakubowski, H; Malinowska, A; Perl A-Kaján, J; Suszyńska-Zajczyk, J; Zimny, JA1
Saito, M; Shiraki, M; Taguchi, A1
Chen, F; Ko, CN; Lee, SM; Leung, CH; Li, D; Li, G; Li, P; Li, S; Lin, L; Ma, DL; Wang, W; Wu, C1

Reviews

11 review(s) available for homocysteine and lysine

ArticleYear
[Diagnosis and management of the aminoacidopathies (author's transl)].
    Diabete & metabolisme, 1978, Volume: 4, Issue:3

    Topics: Amino Acid Metabolism, Inborn Errors; Citric Acid Cycle; Female; Genotype; Homocysteine; Humans; Lysine; Phenylalanine; Pregnancy; Prenatal Diagnosis

1978
Enzymatic reactions involving corrinoids.
    Annual review of biochemistry, 1968, Volume: 37

    Topics: Acetates; Caproates; Enzymes; Homocysteine; Isomerases; Lysine; Methane; Oxidoreductases; Vitamin B 12

1968
Cystinuria.
    The American journal of medicine, 1968, Volume: 45, Issue:5

    Topics: Adolescent; Adult; Arginine; Biological Transport; Chemical Phenomena; Chemistry; Cystine; Cystinuria; Female; Heterozygote; Homocysteine; Homozygote; Humans; Jejunum; Kidney Tubules; Lysine; Male; Middle Aged; Ornithine; Penicillamine; Piperidines; Pyrrolidines

1968
[Assessment of bone quality with metabolic bone markers].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Nov-28, Volume: 65 Suppl 9

    Topics: Alkaline Phosphatase; Amino Acids; Arginine; Biomarkers; Bone and Bones; Bone Resorption; Collagen Type I; Forecasting; Fractures, Bone; Homocysteine; Humans; Lysine; Osteocalcin; Osteogenesis; Peptides; Tensile Strength

2007
[Biochemical markers of bone turnover. New aspect. Bone collagen metabolism: new biological markers for estimation of bone quality].
    Clinical calcium, 2009, Volume: 19, Issue:8

    Topics: Arginine; Biomarkers; Bone and Bones; Bone Density; Bone Remodeling; Bone Resorption; Collagen; Glycation End Products, Advanced; Homocysteine; Humans; Lysine; Osteoporosis; Oxidative Stress

2009
[Poor bone quality in diabetes and arterioscelerosis].
    Clinical calcium, 2009, Volume: 19, Issue:9

    Topics: Animals; Arginine; Arteriosclerosis; Biomarkers; Bone Density; Collagen; Diabetes Complications; Diabetes Mellitus; Fractures, Bone; Glycation End Products, Advanced; Homocysteine; Humans; Lysine; Osteoporosis; Risk

2009
[Bone quality markers: pentosidine, homocysteine, and MTHFR polymorphism].
    Rinsho byori. The Japanese journal of clinical pathology, 2009, Volume: 57, Issue:9

    Topics: Arginine; Biomarkers; Female; Homocysteine; Humans; Lysine; Methylenetetrahydrofolate Reductase (NADPH2); Osteoporosis; Polymorphism, Genetic

2009
[CKD-MBD (Chronic Kidney Disease-Mineral and Bone Disorder). Bone quality in chronic kidney disease : enzymatic and non-enzymatic glycation or oxidation induced cross-links in bone].
    Clinical calcium, 2010, Volume: 20, Issue:7

    Topics: Animals; Arginine; Bone and Bones; Bone Diseases, Metabolic; Chronic Disease; Collagen; Fractures, Bone; Glycation End Products, Advanced; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Lysine; Osteoporosis; Oxidative Stress; Risk

2010
[Is bone biopsy necessary for the diagnosis of metabolic bone diseases? Non- invasive assessment of bone turn over markers could define the cause of metabolic bone diseases].
    Clinical calcium, 2011, Volume: 21, Issue:9

    Topics: Acid Phosphatase; Alkaline Phosphatase; Arginine; Biomarkers; Biopsy; Bone and Bones; Bone Diseases, Metabolic; Collagen Type I; Diagnosis, Differential; Homocysteine; Humans; Isoenzymes; Lysine; Osteoporosis; Peptide Fragments; Peptides; Procollagen; Tartrate-Resistant Acid Phosphatase

2011
[The role of post-translational modification of fibrinogen in the pathogenesis of thrombosis].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2015, Volume: 38, Issue:224

    Topics: Extracellular Space; Fibrin; Fibrinogen; Fibrinolysis; Glycation End Products, Advanced; Halogenation; Homocysteine; Humans; Lysine; Protein Processing, Post-Translational; Thrombosis

2015
[The assessment of bone quality in lifestyle-related diseases].
    Clinical calcium, 2016, Volume: 26, Issue:1

    Topics: Arginine; Biomarkers; Bone and Bones; Bone Remodeling; Collagen; Diabetes Mellitus, Type 2; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Lysine; Osteoporosis; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic; Risk; Tomography, X-Ray Computed

2016

Trials

1 trial(s) available for homocysteine and lysine

ArticleYear
Influence of hemodialysis membrane permeability on serum levels of advanced glycation end products (AGEs) and homocysteine metabolites.
    Clinical nephrology, 2004, Volume: 61, Issue:3

    Topics: Arginine; Cross-Over Studies; Cystathionine; Enzyme-Linked Immunosorbent Assay; Female; Fluorescence; Glycation End Products, Advanced; Homocysteine; Humans; Kidneys, Artificial; Lysine; Male; Membranes, Artificial; Middle Aged; Polymers; Prospective Studies; Renal Dialysis; Sarcosine; Sulfones

2004

Other Studies

56 other study(ies) available for homocysteine and lysine

ArticleYear
Inhibition of human dimethylarginine dimethylaminohydrolase-1 by S-nitroso-L-homocysteine and hydrogen peroxide. Analysis, quantification, and implications for hyperhomocysteinemia.
    The Journal of biological chemistry, 2007, Nov-30, Volume: 282, Issue:48

    Topics: Amidohydrolases; Amino Acid Sequence; Animals; Binding Sites; Cloning, Molecular; Cysteine; Dose-Response Relationship, Drug; Drug Design; Homocysteine; Humans; Hydrogen Peroxide; Hyperhomocysteinemia; Kinetics; Molecular Sequence Data; Oxidation-Reduction; Sequence Homology, Amino Acid; Substrate Specificity

2007
Studies of the mechanism of glutamine synthetase utilizing pH-dependent behavior in catalysis and binding.
    The Journal of biological chemistry, 1987, Mar-05, Volume: 262, Issue:7

    Topics: Adenosine Triphosphate; Amino Acids; Ammonia; Catalysis; Chemical Phenomena; Chemistry; Escherichia coli; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Homocysteine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; Lysine; Methionine Sulfoximine; Protons; Spectrometry, Fluorescence; Substrate Specificity; Sulfonamides

1987
Recognition of aminoethylhomocysteine and aminopropylcysteine by aminoacid transport systems and aminoacyl tRNA synthetases.
    Biochemistry international, 1987, Volume: 15, Issue:1

    Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Arginine; Binding Sites; Biological Transport; Cricetinae; Cricetulus; Cysteine; Escherichia coli; Homocysteine; Lysine; Structure-Activity Relationship

1987
Effects of carcinogens and other agents on histone methylation in rat liver nuclei by endogenous histone lysine methyltransferase.
    Cancer research, 1974, Volume: 34, Issue:6

    Topics: Adenosine; Animals; Azo Compounds; Benz(a)Anthracenes; Carbon Radioisotopes; Carcinogens; Cell Nucleus; Dimethylformamide; Ethionine; Fluorenes; Histones; Homocysteine; Liver; Lysine; Mesylates; Methylation; Methyltransferases; Nitrosamines; Nitrosoguanidines; Nitrosourea Compounds; Pyrimidines; Pyrroles; Rats; Ribonucleosides; S-Adenosylmethionine

1974
Methionine, DL-homocysteine thiolactone and n-acetyl-DL-methionine for ruminants.
    Journal of animal science, 1974, Volume: 39, Issue:3

    Topics: Abomasum; Amino Acids; Amino Acids, Sulfur; Animals; Homocysteine; Intestinal Absorption; Lactones; Lysine; Male; Methionine; Rumen; Sheep; Threonine

1974
Thin-layer chromatographic screening of amino acids in plasma and urine of newborns.
    Clinical chemistry, 1974, Volume: 20, Issue:11

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Arginine; Blood Proteins; Chromatography, Thin Layer; Female; Glycine; Homocysteine; Humans; Indicators and Reagents; Infant, Newborn; Infant, Premature; Lysine; Methionine; Phenylalanine; Pregnancy; Proteinuria; Tyrosine; Ultrafiltration

1974
[Modification of aminoaciduria in the rat after administration of cycloleucine: comparison with human cystinuria].
    Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 33, Issue:2

    Topics: Amino Acids; Animals; Antineoplastic Agents; Arginine; Chromatography, Ion Exchange; Chromatography, Paper; Cyclopentanes; Cysteine; Cystine; Cystinuria; Diet; Disulfides; Diuresis; Electrophoresis; Homocysteine; Injections, Intraperitoneal; Lysine; Male; Metabolism; Ornithine; Paper; Rats; Time Factors

1971
Amino acid excretion patterns in the offspring of a 'doubly-heterozygous' cystine stone former.
    Experientia, 1970, Dec-15, Volume: 26, Issue:12

    Topics: Alleles; Amino Acid Metabolism, Inborn Errors; Amino Acids; Arginine; Child; Child, Preschool; Chromatography, Paper; Cysteine; Cystinosis; Cystinuria; Female; Ferrocyanides; Heterozygote; Homocysteine; Humans; Lysine; Molecular Biology; Ornithine

1970
Detection of several non-protein amino acids in the presence of protein amino acids.
    Journal of chromatography, 1971, Feb-03, Volume: 54, Issue:3

    Topics: Alanine; Amino Acids; Aminobutyrates; Autoanalysis; Betaine; Chromatography; Homocysteine; Hydroxyproline; Isoleucine; Lysine; Methionine; Phenylalanine; Pimelic Acids; Proteins; Sarcosine; Taurine; Urea

1971
Analysis of carboxymethylated residues in proteins by an isotopic method, and its application to the bromoacetate-ribonuclease reaction.
    Archives of biochemistry and biophysics, 1968, Volume: 126, Issue:2

    Topics: Acetates; Amino Acids; Aspartic Acid; Autoanalysis; Carbon Isotopes; Glycolates; Histidine; Homocysteine; Hydrogen-Ion Concentration; Indicators and Reagents; Iodoacetates; Lysine; Methionine; Methods; Proteins; Ribonucleases; Sulfonic Acids; Time Factors

1968
Heavy atom-labelled derivatives of bovine pancreatic ribonuclease. I. Specific reactions of ribonuclease with N-acetylhomocysteine thiolactone and silver ion.
    Journal of molecular biology, 1969, Volume: 41, Issue:2

    Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography; Homocysteine; Lactones; Lysine; Pancreas; Ribonucleases; Silver

1969
Synthesis of some dibasic sulphur-containing amino-acids related to L-lysine.
    Journal of the Chemical Society. Perkin transactions 1, 1966, Volume: 12

    Topics: Chemical Phenomena; Chemistry; Cysteine; Homocysteine; Lysine

1966
Generation and initial characterization of a novel polyclonal antibody directed against homocysteine thiolactone-modified low density lipoprotein.
    Journal of lipid research, 1998, Volume: 39, Issue:4

    Topics: Antibody Specificity; Apolipoprotein B-100; Apolipoproteins B; Binding, Competitive; Cystamine; Enzyme-Linked Immunosorbent Assay; Homocysteine; Lipoproteins, LDL; Lysine; Vascular Diseases

1998
Enzymatic and chemical modifications of lipoprotein(a) selectively alter its lysine-binding functions.
    Biochimica et biophysica acta, 1998, May-20, Volume: 1392, Issue:1

    Topics: Acetylcysteine; Amidines; Binding Sites; Chromatography, Affinity; Copper Sulfate; Homocysteine; Immunoassay; Lipoprotein(a); Lysine; Oxidation-Reduction; Phospholipases A; Phospholipases A2

1998
Addition of arginine but not glycine to lysine plus methionine-enriched diets modulates serum cholesterol and liver phospholipids in rabbits.
    The Journal of nutrition, 1999, Volume: 129, Issue:10

    Topics: Amino Acids; Analysis of Variance; Animals; Arginine; Body Weight; Cholesterol; Diet; Drug Interactions; Glycine; Homocysteine; Hypercholesterolemia; Lipoproteins; Liver; Lysine; Male; Methionine; Phospholipids; Rabbits

1999
Homocysteine thiolactone and protein homocysteinylation: mechanistic studies with model peptides and proteins.
    Rapid communications in mass spectrometry : RCM, 2002, Volume: 16, Issue:11

    Topics: Homocysteine; Lysine; Mass Spectrometry; Peptides; Protein Binding

2002
Serum levels of total homocysteine, homocysteine metabolites and of advanced glycation end-products (AGEs) in patients after renal transplantation.
    Clinical nephrology, 2003, Volume: 59, Issue:2

    Topics: Adult; Arginine; Coronary Disease; Cystathionine; Female; Glycation End Products, Advanced; Homocysteine; Humans; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Kidney Transplantation; Logistic Models; Lysine; Male; Methylmalonic Acid; Middle Aged; Risk Factors

2003
Effects of ramipril in nondiabetic nephropathy: improved parameters of oxidatives stress and potential modulation of advanced glycation end products.
    Journal of human hypertension, 2003, Volume: 17, Issue:4

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Blood Glucose; Blood Pressure; Creatinine; Cystatin C; Cystatins; Diabetic Nephropathies; Female; Glomerulonephritis; Glycation End Products, Advanced; Homocysteine; Humans; Lipofuscin; Lysine; Male; Malondialdehyde; Middle Aged; Nephritis, Interstitial; Oxidative Stress; Polycystic Kidney Diseases; Ramipril; Severity of Illness Index; Statistics as Topic; Treatment Outcome

2003
Effect of smoking on risk factors for cardiovascular disease in patients with diabetes mellitus and renal insufficiency.
    European journal of medical research, 2003, Jul-31, Volume: 8, Issue:7

    Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Homocysteine; Humans; Kidney Transplantation; Lysine; Middle Aged; Renal Dialysis; Renal Insufficiency; Risk Factors; Smoking

2003
EFFECT OF PENICILLAMINE ON CYSTINURIA.
    Investigative urology, 1965, Volume: 2

    Topics: Arginine; Body Fluids; Cysteine; Cystinuria; Drug Therapy; Homocysteine; Humans; Lysine; Ornithine; Penicillamine; Urine

1965
Association between blood indoxyl sulfate and carbonyl stress marker in hemodialysis patients.
    Clinical nephrology, 2003, Volume: 60, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Arginine; Biomarkers; Blood Proteins; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Homocysteine; Humans; Indican; Lysine; Male; Middle Aged; Regression Analysis; Renal Dialysis; Time Factors

2003
Cross-talk between Cys34 and lysine residues in human serum albumin revealed by N-homocysteinylation.
    The Journal of biological chemistry, 2004, Mar-19, Volume: 279, Issue:12

    Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cysteine; Homocysteine; Humans; Hydrolysis; Lysine; Oxidation-Reduction; Serum Albumin

2004
Autoantibodies against N-homocysteinylated proteins in humans: implications for atherosclerosis.
    Stroke, 2004, Volume: 35, Issue:6

    Topics: Aged; Arteriosclerosis; Autoantibodies; Blood Proteins; Epitopes; Female; Homocysteine; Humans; Immunoglobulin G; Lysine; Male; Middle Aged; Stroke

2004
Substrate specificity and kinetic mechanism of mammalian G9a histone H3 methyltransferase.
    The Journal of biological chemistry, 2004, Dec-17, Volume: 279, Issue:51

    Topics: Alanine; Animals; Baculoviridae; Binding, Competitive; Catalysis; Cell Line; Dimerization; Dose-Response Relationship, Drug; Genetic Vectors; Genome; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Homocysteine; Hydrogen-Ion Concentration; Insecta; Kinetics; Lysine; Mass Spectrometry; Methylation; Mice; Models, Chemical; Models, Genetic; Peptides; Phosphorylation; Protein Isoforms; Protein Methyltransferases; Recombinant Proteins; Substrate Specificity; Temperature; Time Factors

2004
S-adenosylhomocysteine hydrolase from the archaeon Pyrococcus furiosus: biochemical characterization and analysis of protein structure by comparative molecular modeling.
    Proteins, 2005, Mar-01, Volume: 58, Issue:4

    Topics: Adenosine; Adenosylhomocysteinase; Amino Acid Sequence; Catalysis; Cloning, Molecular; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Homocysteine; Hot Temperature; Kinetics; Lysine; Methylation; Models, Molecular; Molecular Sequence Data; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyrococcus; Pyrococcus furiosus; Recombinant Proteins; Sequence Homology, Amino Acid; Sulfolobus solfataricus; Temperature; Threonine

2005
Modification of fibrinogen by homocysteine thiolactone increases resistance to fibrinolysis: a potential mechanism of the thrombotic tendency in hyperhomocysteinemia.
    Biochemistry, 2006, Feb-28, Volume: 45, Issue:8

    Topics: Amino Acid Sequence; Blood Coagulation; Dose-Response Relationship, Drug; Fibrin; Fibrinogen; Fibrinolysis; Homocysteine; Humans; Hyperhomocysteinemia; Lysine; Models, Biological; Molecular Sequence Data; Plasminogen; Protein Binding; Radiation-Protective Agents; Structure-Activity Relationship; Thrombosis; Tissue Plasminogen Activator

2006
Reductions in degree of mineralization and enzymatic collagen cross-links and increases in glycation-induced pentosidine in the femoral neck cortex in cases of femoral neck fracture.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2006, Volume: 17, Issue:7

    Topics: Aged; Aged, 80 and over; Arginine; Bone Density; Calcification, Physiologic; Collagen; Female; Femoral Neck Fractures; Femur Neck; Glycosylation; Homocysteine; Humans; Hydroxylation; Lysine; Protein Processing, Post-Translational

2006
Pathophysiological consequences of homocysteine excess.
    The Journal of nutrition, 2006, Volume: 136, Issue:6 Suppl

    Topics: Autoantibodies; Blood Proteins; Cell Death; Diet; Endoplasmic Reticulum; Homocysteine; Humans; Hyperhomocysteinemia; Lysine; Methionine; Protein Binding

2006
Role of vitamin E-coated membrane in reducing advanced glycation end products in hemodialysis patients: a pilot study.
    Blood purification, 2006, Volume: 24, Issue:4

    Topics: Aged; Analysis of Variance; Antioxidants; Arginine; Brachial Artery; Endothelium, Vascular; Female; Glycation End Products, Advanced; Homocysteine; Humans; Linear Models; Lipoproteins, LDL; Lysine; Male; Membranes, Artificial; Middle Aged; Oxidative Stress; Pilot Projects; Renal Dialysis; Vasodilation; Vitamin E

2006
Plasma pentosidine and total homocysteine levels in relation to change in common carotid intima-media area in the first year of dialysis therapy.
    Clinical nephrology, 2006, Volume: 66, Issue:6

    Topics: Adult; Arginine; Atherosclerosis; Biomarkers; Carotid Artery, Common; Chromatography, High Pressure Liquid; Female; Follow-Up Studies; Glycation End Products, Advanced; Homocysteine; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Organophosphates; Prognosis; Prospective Studies; Renal Dialysis; Severity of Illness Index; Time Factors; Tunica Intima; Ultrasonography

2006
Modification by homocysteine thiolactone affects redox status of cytochrome C.
    Biochemistry, 2007, May-29, Volume: 46, Issue:21

    Topics: Animals; Binding Sites; Circular Dichroism; Cytochromes c; Homocysteine; Horses; Hyperhomocysteinemia; Lysine; Oxidation-Reduction; Protein Processing, Post-Translational; Protein Structure, Secondary

2007
Characteristics of methionine production by an engineered Corynebacterium glutamicum strain.
    Metabolic engineering, 2007, Volume: 9, Issue:4

    Topics: Bacterial Proteins; Corynebacterium glutamicum; Ethionine; Gene Expression Regulation, Bacterial; Homocysteine; Lysine; Methionine; Mutation; Threonine

2007
Interleukin-6 is a better predictor of mortality as compared to C-reactive protein, homocysteine, pentosidine and advanced oxidation protein products in hemodialysis patients.
    Blood purification, 2008, Volume: 26, Issue:2

    Topics: Adult; Arginine; C-Reactive Protein; Female; Glycation End Products, Advanced; Homocysteine; Humans; Interleukin-6; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Oxidation-Reduction; Prognosis; Proteins; Renal Dialysis; Survival Rate

2008
Human serum albumin as a catalyst of RNA cleavage: N-homocysteinylation and N-phosphorylation by oligonucleotide affinity reagent alter the reactivity of the protein.
    Bioorganic & medicinal chemistry letters, 2008, Oct-15, Volume: 18, Issue:20

    Topics: Catalysis; Electrophoresis, Polyacrylamide Gel; Homocysteine; Humans; Hydrolysis; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Statistical; Oligonucleotides; Phosphorylation; RNA; Serum Albumin; Tyrosine

2008
Homocystamides promote free-radical and oxidative damage to proteins.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Jan-12, Volume: 107, Issue:2

    Topics: Alzheimer Disease; Cardiovascular Diseases; Congenital Abnormalities; Free Radicals; Homocysteine; Humans; Hydrogen Bonding; Kinetics; Lysine; Osteoporosis; Oxidative Stress; Protein Processing, Post-Translational; Renal Insufficiency; Serum Albumin

2010
Urinary pentosidine and plasma homocysteine levels at baseline predict future fractures in osteoporosis patients under bisphosphonate treatment.
    Journal of bone and mineral metabolism, 2011, Volume: 29, Issue:1

    Topics: Aged; Arginine; Bone Density; Bone Density Conservation Agents; Diphosphonates; Female; Fractures, Bone; Homocysteine; Humans; Lysine; Middle Aged; Osteoporosis; Proportional Hazards Models

2011
Direct monitoring of albumin lysine-525 N-homocysteinylation in human serum by liquid chromatography/mass spectrometry.
    Analytical biochemistry, 2010, Oct-01, Volume: 405, Issue:1

    Topics: Amino Acid Sequence; Chromatography, Liquid; Cystathionine beta-Synthase; Homocysteine; Humans; Lysine; Mass Spectrometry; Protein Processing, Post-Translational; Serum Albumin

2010
Comparison of the effect of homocysteine in the reduced form, its thiolactone and protein homocysteinylation on hemostatic properties of plasma.
    Thrombosis research, 2011, Volume: 127, Issue:3

    Topics: Adult; Blood Coagulation; Blood Proteins; Fibrinogen; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia; Lysine; Oxidation-Reduction; Sulfhydryl Compounds

2011
Analysis of site-specific N-homocysteinylation of human serum albumin in vitro and in vivo using MALDI-ToF and LC-MS/MS mass spectrometry.
    Journal of proteomics, 2011, Jun-10, Volume: 74, Issue:7

    Topics: Amino Acid Sequence; Chromatography, Liquid; Homocysteine; Humans; Lysine; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry

2011
Ageing in Werner syndrome.
    Bioscience trends, 2012, Volume: 6, Issue:1

    Topics: Adult; Aged, 80 and over; Aging; Arginine; Female; Health; Homocysteine; Humans; Lysine; Male; Middle Aged; Werner Syndrome

2012
Plasma level of homocysteine associated with severe vertebral fracture in postmenopausal women.
    Calcified tissue international, 2013, Volume: 93, Issue:3

    Topics: Aged; Arginine; Body Mass Index; Bone Density; Cohort Studies; Cross-Sectional Studies; Female; Homocysteine; Humans; Japan; Logistic Models; Lysine; Middle Aged; Odds Ratio; Osteoporosis, Postmenopausal; Prevalence; Regression Analysis; Reproducibility of Results; Risk Factors; Spinal Fractures

2013
Characterization of N-homocysteinylated albumin adducts.
    The protein journal, 2014, Volume: 33, Issue:1

    Topics: Homocysteine; Humans; Lysine; Methionine; Serum Albumin

2014
Creation of catalytically active particles from enzymes crosslinked with a natural bifunctional agent--homocysteine thiolactone.
    Biopolymers, 2014, Volume: 101, Issue:9

    Topics: Animals; Calorimetry, Differential Scanning; Catalysis; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Homocysteine; Hydrodynamics; L-Lactate Dehydrogenase; Lysine; Microscopy, Electron, Transmission; Models, Molecular; NAD; Rabbits

2014
Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Animals; Base Sequence; Cell Line; Collagen Type I; Collagen Type I, alpha 1 Chain; Down-Regulation; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Homocysteine; Humans; Liver; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Promoter Regions, Genetic; Repressor Proteins

2015
N- and S-homocysteinylation reduce the binding of human serum albumin to catechins.
    European journal of nutrition, 2017, Volume: 56, Issue:2

    Topics: Aminoacylation; Catechin; Cysteine; Electrophoresis, Capillary; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Ligands; Lysine; Protein Processing, Post-Translational; Serum Albumin; Serum Albumin, Human

2017
Factors related to curved femur in elderly Japanese women.
    Upsala journal of medical sciences, 2016, Volume: 121, Issue:3

    Topics: Aged; Aged, 80 and over; Arginine; Bone Density; Calcium; Female; Femoral Fractures; Femur; Homocysteine; Humans; Japan; Lumbar Vertebrae; Lysine; Middle Aged; Multivariate Analysis; Odds Ratio; Parathyroid Hormone; Regression Analysis; Vitamin D; Vitamin D Deficiency

2016
N-Homocysteinylation impairs collagen cross-linking in cystathionine β-synthase-deficient mice: a novel mechanism of connective tissue abnormalities.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016, Volume: 30, Issue:11

    Topics: Animals; Collagen Type I; Collagen Type I, alpha 1 Chain; Connective Tissue; Cystathionine beta-Synthase; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Lysine; Mice, Knockout; Peptides

2016
Dehomocysteinylation is catalysed by the sirtuin-2-like bacterial lysine deacetylase CobB.
    The FEBS journal, 2016, Volume: 283, Issue:22

    Topics: Animals; Bacterial Proteins; Carboxylic Ester Hydrolases; Cattle; HEK293 Cells; Histone Deacetylases; Homocysteine; Humans; Immunoblotting; Kinetics; Lysine; Mice; Models, Chemical; Molecular Structure; Mutation; NIH 3T3 Cells; Protein Processing, Post-Translational; Serum Albumin, Bovine; Sirtuin 2

2016
Effect of arginine:lysine and glycine:methionine intake ratios on dyslipidemia and selected biomarkers implicated in cardiovascular disease: A study with hypercholesterolemic rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 91

    Topics: Administration, Oral; Amino Acids; Animals; Arginine; Biomarkers; Body Weight; Cardiovascular Diseases; Dyslipidemias; Glycine; Homocysteine; Hypercholesterolemia; Lipids; Liver; Lysine; Male; Methionine; Nitric Oxide; Organ Size; Rats, Wistar

2017
Pentosidine concentration is associated with degenerative lumbar scoliosis in older women: preliminary results.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2018, Volume: 27, Issue:3

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Arginine; Biomarkers; Calcifediol; Calcitriol; Case-Control Studies; Female; Femur; Homocysteine; Humans; Kyphosis; Lordosis; Lumbar Vertebrae; Lysine; Middle Aged; Sarcopenia; Scoliosis; Spine

2018
Modification of erythropoietin structure by N-homocysteinylation affects its antiapoptotic and proliferative functions.
    The FEBS journal, 2018, Volume: 285, Issue:20

    Topics: Apoptosis; Cell Proliferation; Cells, Cultured; Erythropoietin; Homocysteine; Humans; Lysine; Megakaryocytes; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Secondary

2018
Colonic Lysine Homocysteinylation Induced by High-Fat Diet Suppresses DNA Damage Repair.
    Cell reports, 2018, 10-09, Volume: 25, Issue:2

    Topics: Animals; Apoptosis; Case-Control Studies; Cell Proliferation; Colonic Neoplasms; Diet, High-Fat; DNA Damage; DNA Repair; Homocysteine; Humans; Lysine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Protein Processing, Post-Translational; Rats; Rats, Wistar; Rectal Neoplasms; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2018
Sex affects N-homocysteinylation at lysine residue 212 of albumin in mice.
    Scientific reports, 2019, 02-25, Volume: 9, Issue:1

    Topics: Animals; Binding Sites; Chromatography, Liquid; Cystathionine beta-Synthase; Female; Genotype; Homocysteine; Humans; Lysine; Male; Mass Spectrometry; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Serum Albumin; Sex Factors

2019
Proteome-Wide Analysis of Protein Lysine
    Journal of proteome research, 2021, 05-07, Volume: 20, Issue:5

    Topics: Animals; Homocysteine; Humans; Lysine; Protein Processing, Post-Translational; Proteome; Saccharomyces cerevisiae

2021
Association of pentosidine and homocysteine levels with number of teeth present in Japanese postmenopausal women.
    Journal of bone and mineral metabolism, 2022, Volume: 40, Issue:5

    Topics: Aged; Arginine; Bone Density; Female; Homocysteine; Humans; Japan; Lysine; Postmenopause; Tooth Loss

2022
Homocysteine-targeting compounds as a new treatment strategy for diabetic wounds via inhibition of the histone methyltransferase SET7/9.
    Experimental & molecular medicine, 2022, Volume: 54, Issue:7

    Topics: Animals; Diabetes Mellitus; Histone Methyltransferases; Homocysteine; Hyperglycemia; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lysine; Mice; Neovascularization, Pathologic

2022