homocysteine has been researched along with levoleucovorin in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.09) | 18.7374 |
| 1990's | 4 (12.12) | 18.2507 |
| 2000's | 14 (42.42) | 29.6817 |
| 2010's | 10 (30.30) | 24.3611 |
| 2020's | 2 (6.06) | 2.80 |
| Authors | Studies |
|---|---|
| Benesh, FC; Carl, GF | 1 |
| Schulman, LH | 1 |
| Blom, HJ; Eskes, TK; Monnens, IA; te Poele Pothoff, MT; van den Heuvel, LP; van der Molen, EF | 1 |
| Girgis, S; Jolivet, J; Stover, PJ; Suh, JR | 1 |
| Geisler, J; Geisler, SB; Lønning, PE; Refsum, H; Smaaland, R; Tveit, KM; Ueland, PM | 1 |
| Massy, ZA | 1 |
| Applegarth, DA; Hadorn, HB; Randak, C; Rolinski, B; Roscher, AA; Roschinger, W | 1 |
| Bagley, PJ; Rosenberg, IH; Selhub, J; Stern, LL | 1 |
| Bostom, AG; Dworkin, L; Hsu, N; Jacques, PF; Selhub, J; Shemin, D; Yango, A | 1 |
| Apsner, R; Bieglmayer, C; Buchmayer, H; Födinger, M; Hagen, W; Hauser, AC; Hörl, WH; Ignatescu, M; Köller, E; Papagiannopoulos, M; Rehak, PH; Sunder-Plassmann, G | 1 |
| Chango, A; James, SJ; Melnyk, S; Pogribna, M; Pogribny, I; Yi, P | 1 |
| Blasco, C; Fabre, E; Gallo, M; González De Agüero, R; Juste, G; Lou, AC; Reyes-Engel, A; Romero, MS; Sobreviela, M | 1 |
| Blom, HJ; Boers, GH; De Boo, TM; Haagsma, CJ; Laan, RF; Thomas, CM; van de Putte, LB; van Ede, AE | 1 |
| Apeland, T; Brønstad, I; Gøransson, L; Mansoor, MA; Seljeflot, I; Strandjord, RE | 1 |
| MARCHETTI, M; MORUZZI, G; VIVIANI, R | 1 |
| Armada, E; Camba, M; Esteban, J; Gayoso, P; Otero, A; Pérez, C; Suárez, D | 1 |
| Alarcón, GS; Baggott, JE; Lee, JY; Morgan, SL; Oster, RA | 1 |
| Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA | 1 |
| Demlova, R; Dusek, L; Sterba, J; Valik, D | 1 |
| Heyrovský, M; Kohlíková, E; Navrátil, T; Pelclová, D; Petr, M; Pristoupil, TI; Pristoupilová, K; Senholdová, Z | 1 |
| Hyspler, R; Kalábová, H; Kasparová, M; Krcmová, L; Malírová, E; Melichar, B; Melicharová, K; Pecka, M; Solichová, D | 1 |
| Kitamura, Y; Kusuhara, H; Sugiyama, Y | 1 |
| Blom, HJ; den Heijer, M; Gunnewiek, JK; Hogeveen, M; Ijland, M; Schonbeck, Y; van Oppenraaij, D | 1 |
| Foroozanfard, F; Mianehsaz, E; Moraveji, SA; Nasiri, O; Nikoueinejad, H; Rajali, M; Soleimani, A; Usefzadeh, M | 1 |
| Adleff, V; Budai, B; Hitre, E; Komlósi, V; Kralovánszky, J; Láng, I; Nagy, T; Pap, É; Réti, A | 1 |
| Benoist, JF; Cornec-Le Gall, E; De Parscau, L; Delmas, Y; Doucet, L; Fremeaux-Bacchi, V; Le Meur, Y; Ogier, H | 1 |
| Guan, Z; Niu, B; Wang, J; Wang, X; Wang, Z; Xie, Q; Zhang, T; Zhao, X; Zhu, Z | 1 |
| Cortés Rodríuez, M; Lendinez, AM; Palomares, AR; Perez-Nevot, B; Reyes-Engel, A; Ruiz-Galdon, M | 1 |
| Ansseau, M; Boemer, F; Bours, V; Philippe, P; Quadros, EV; Ramaekers, VT; Sequeira, JM; Thöny, B | 1 |
| Blom, HJ; Castro, R; Esse, R; Koolwijk, P; Tavares de Almeida, I; Teerlink, T | 1 |
| de Jonge, R; Fiocco, M; Heil, SG; Oosterom, N; Pieters, R; Smith, DEC; Tissing, WJE; van den Heuvel-Eibrink, MM; van Zelst, BD | 1 |
| Braconnier, A; Desmons, A; Garnotel, R; Gillery, P; Jaisson, S; Rieu, P; Wynckel, A | 1 |
| Mazokopakis, EE; Papadakis, JA; Papadomanolaki, MG | 1 |
1 review(s) available for homocysteine and levoleucovorin
| Article | Year |
|---|---|
Methyl biogenesis.
Topics: Folic Acid; Homocysteine; Humans; Leucovorin; Mental Disorders; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Tetrahydrofolates | 1978 |
7 trial(s) available for homocysteine and levoleucovorin
| Article | Year |
|---|---|
Changes in folate status as determined by reduction in total plasma homocysteine levels during leucovorin modulation of 5-fluorouracil therapy in cancer patients.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colorectal Neoplasms; Creatinine; Erythrocytes; Female; Fluorouracil; Folic Acid; Homocysteine; Humans; Leucovorin; Male; Middle Aged; Vitamin B 12 | 1998 |
Rapid communication: L-folinic acid versus folic acid for the treatment of hyperhomocysteinemia in hemodialysis patients.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Leucovorin; Male; Middle Aged; Renal Dialysis; Treatment Outcome | 2001 |
Efficacy of folinic versus folic acid for the correction of hyperhomocysteinemia in hemodialysis patients.
Topics: Double-Blind Method; Drug Administration Schedule; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infusions, Intravenous; Leucovorin; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Renal Dialysis; Treatment Outcome; Vitamin B 12 | 2001 |
Homocysteine and folate status in methotrexate-treated patients with rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Daunorubicin; Female; Folic Acid; Genotype; Homocysteine; Humans; Leucovorin; Linear Models; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation | 2002 |
The effect of folic acid and folinic acid supplements on purine metabolism in methotrexate-treated rheumatoid arthritis.
Topics: Adenosine; Aminoimidazole Carboxamide; Arthritis, Rheumatoid; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Purines; Pyridoxine; Ribonucleotides; Treatment Outcome; Vitamin B 12 | 2004 |
The effect of folinic acid supplementation on homocysteine concentrations in newborns.
Topics: Cerebrovascular Disorders; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Leucovorin; Male; Prospective Studies; Risk Factors | 2010 |
Comparison of oral folic acid and folinic acid on blood homocysteine level of patients on hemodialysis.
Topics: Administration, Oral; Biomarkers; Female; Folic Acid; Homocysteine; Humans; Leucovorin; Male; Middle Aged; Renal Dialysis; Statistics, Nonparametric | 2011 |
25 other study(ies) available for homocysteine and levoleucovorin
| Article | Year |
|---|---|
Structure and function of E. coli formylmethionyl tRNA. I. Effect of modification of pyrimidine residues on aminoacyl synthetase recognition.
Topics: Amino Acids; Carbon Isotopes; Chromatography, DEAE-Cellulose; Escherichia coli; Formates; Homocysteine; Leucovorin; Ligases; Methionine; Nucleotides; Radiation Effects; Ribonucleases; RNA, Transfer; Spectrum Analysis; Transferases; Ultraviolet Rays | 1970 |
The effect of folic acid on the homocysteine metabolism in human umbilical vein endothelial cells (HUVECs).
Topics: Cells, Cultured; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Kinetics; Leucovorin; Tetrahydrofolates; Time Factors; Umbilical Veins | 1996 |
5-Formyltetrahydrofolate regulates homocysteine remethylation in human neuroblastoma.
Topics: Antidotes; Gene Expression; Homocysteine; Humans; Leucovorin; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Neuroblastoma; Tumor Cells, Cultured | 1997 |
Reversal of hyperhomocyst(e)inaemia in chronic renal failure-is folic or folinic acid the answer?
Topics: Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Leucovorin | 1999 |
Three siblings with nonketotic hyperglycinaemia, mildly elevated plasma homocysteine concentrations and moderate methylmalonic aciduria.
Topics: Child; Consanguinity; Female; Homocysteine; Humans; Hyperglycinemia, Nonketotic; Infant; Infant, Newborn; Leucovorin; Male; Methylmalonic Acid; Nuclear Family | 2000 |
Conversion of 5-formyltetrahydrofolic acid to 5-methyltetrahydrofolic acid is unimpaired in folate-adequate persons homozygous for the C677T mutation in the methylenetetrahydrofolate reductase gene.
Topics: Administration, Oral; Adult; Area Under Curve; Female; Folic Acid; Genotype; Homocysteine; Humans; Leucovorin; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Tetrahydrofolates | 2000 |
Homocysteine metabolism in children with Down syndrome: in vitro modulation.
Topics: Adenosine; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cystathionine beta-Synthase; Cysteine; DNA Methylation; Down Syndrome; Glutathione; Homocysteine; Humans; Leucovorin; Lymphocytes; Methionine; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Superoxide Dismutase; Thymidine; Vitamin B 12 | 2001 |
[Effects of levofolinic acid on plasma homocysteine concentrations in healthy and young women in preconceptional care].
Topics: Adult; Female; Homocysteine; Humans; Leucovorin; Neural Tube Defects; Preconception Care | 2001 |
Homocysteine, malondialdehyde and endothelial markers in dialysis patients during low-dose folinic acid therapy.
Topics: Creatinine; Endothelium, Vascular; Female; Hemoglobins; Homocysteine; Humans; Infusions, Intravenous; Kidney Failure, Chronic; Leucovorin; Longitudinal Studies; Male; Malondialdehyde; Middle Aged; Mutation; Renal Dialysis; Serum Albumin | 2002 |
OROTIC ACID AND METABOLISM OF ONE CARBON UNIT: CONVERSION OF FOLIC ACID TO CITROVORUM FACTOR AND METHIONINE SYNTHESIS IN CHICK LIVER.
Topics: Animals; Carbon; Chickens; Folic Acid; Homocysteine; Leuconostoc; Leucovorin; Liver; Metabolism; Methionine; Orotic Acid; Poultry; Proteins; Research; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 1963 |
Neither folic nor folinic acid normalize homocysteine levels in hemodialysis patients.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Leucovorin; Linear Models; Male; Middle Aged; Prospective Studies; Renal Dialysis; Statistics, Nonparametric; Vitamin B 6 | 2003 |
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2004 |
Pretreatment plasma folate modulates the pharmacodynamic effect of high-dose methotrexate in children with acute lymphoblastic leukemia and non-Hodgkin lymphoma: "folate overrescue" concept revisited.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Infant; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vitamin B 12; Vitamin B Complex | 2006 |
Diagnostic significance of urinary thiodiglycolic acid as a possible tool for studying the role of vitamins B12 and folates in the metabolism of thiolic substances.
Topics: Adult; Betaine; Biomarkers; Folic Acid; Homocysteine; Humans; Injections, Intramuscular; Leucovorin; Male; Sulfhydryl Compounds; Thioglycolates; Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
Serum homocysteine, cholesterol, retinol, alpha-tocopherol, glycosylated hemoglobin and inflammatory response during therapy with bevacizumab, oxaliplatin, 5-fluorouracil and leucovorin.
Topics: Adult; Aged; alpha-Tocopherol; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Atherosclerosis; Bevacizumab; Cholesterol; Colorectal Neoplasms; Female; Fluorouracil; Glycated Hemoglobin; Homocysteine; Humans; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Vitamin A | 2009 |
Basolateral efflux mediated by multidrug resistance-associated protein 3 (Mrp3/Abcc3) facilitates intestinal absorption of folates in mouse.
Topics: Animals; Folic Acid; Gene Deletion; Homocysteine; Intestinal Absorption; Leucovorin; Male; Mice; Multidrug Resistance-Associated Proteins; Tetrahydrofolates; Vitamin B 12 | 2010 |
Impact of SHMT1 polymorphism on the clinical outcome of patients with metastatic colorectal cancer treated with first-line FOLFIRI+bevacizumab.
Topics: 3' Untranslated Regions; 5' Untranslated Regions; Alleles; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Creatinine; Dihydrouracil Dehydrogenase (NADP); Disease-Free Survival; Fluorouracil; Genetic Association Studies; Glycine Hydroxymethyltransferase; Homocysteine; Humans; Hypertension; INDEL Mutation; Leucovorin; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Prognosis; Thymidylate Synthase; Treatment Outcome | 2012 |
Adult-onset eculizumab-resistant hemolytic uremic syndrome associated with cobalamin C deficiency.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Antibodies, Monoclonal, Humanized; Betaine; Biopsy; Carrier Proteins; Diagnosis, Differential; Drug Resistance; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Hypertension, Malignant; Immunologic Factors; Kidney; Kidney Function Tests; Leucovorin; Lipotropic Agents; Male; Methionine; Methylmalonic Acid; Mutation; Oxidoreductases; Recurrence; Renal Dialysis; Treatment Outcome; Vitamin B 12 Deficiency; Vitamin B Complex | 2014 |
Quantification of folate metabolites in serum using ultraperformance liquid chromatography tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Leucovorin; Limit of Detection; Neural Tube Defects; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry; Tetrahydrofolates | 2014 |
Differential behavior of serum and red blood cell folate during a treatment with levofolinic acid. Gender differences.
Topics: Administration, Oral; Adolescent; Adult; Dietary Supplements; Drug Administration Schedule; Erythrocytes; Female; Homocysteine; Humans; Leucovorin; Male; Sex Factors; Time Factors; Vitamin B Complex; Young Adult | 2014 |
Folinic acid treatment for schizophrenia associated with folate receptor autoantibodies.
Topics: Adolescent; Adult; Autoantibodies; Biopterins; Child; Female; Folate Receptor 1; Folic Acid; Homocysteine; Humans; Leucovorin; Male; Middle Aged; Schizophrenia; Young Adult | 2014 |
Folinic Acid Increases Protein Arginine Methylation in Human Endothelial Cells.
Topics: Arginine; Cells, Cultured; Dose-Response Relationship, Drug; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Leucovorin; Methionine; Methylation; Protein Processing, Post-Translational; S-Adenosylhomocysteine | 2018 |
Changes in intracellular folate metabolism during high-dose methotrexate and Leucovorin rescue therapy in children with acute lymphoblastic leukemia.
Topics: Adolescent; Antidotes; Child; Child, Preschool; Erythrocytes; Female; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Infant; Leucovorin; Male; Metabolic Networks and Pathways; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Vitamin B 12 | 2019 |
An unusually high plasma concentration of homocysteine resulting from a combination of so-called "secondary" etiologies.
Topics: Aged; Betaine; Female; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Leucovorin; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Psychotic Disorders; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2020 |
The effects of folinic acid and l-methylfolate supplementation on serum total homocysteine levels in healthy adults.
Topics: Adult; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Leucovorin; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged | 2023 |