homocysteine and hydroxocobalamin

homocysteine has been researched along with hydroxocobalamin in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19907 (21.21)18.7374
1990's3 (9.09)18.2507
2000's14 (42.42)29.6817
2010's7 (21.21)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Bertilsson, L; Neujahr, HY1
Taylor, RT1
Brodie, JD; Burke, GT; Mangum, JH1
Mahoney, MJ; Mudd, SH; Rosenberg, LE; Uhlendorf, BW1
Hinds, KR; Mudd, SH; Uhlendorf, BW1
Goodman, SI; Hammond, KB; Moe, PG; Mudd, SH; Uhlendorf, BW1
Bedros, AA; Carmel, R; Goodman, SI; Mace, JW1
Matthews, JH1
Blom, HJ; Bos, GM; Brouwer, IA; den Heijer, M; Gerrits, WB; Haak, HL; Rosendaal, FR; Spaans, AP; Thomas, CM; van der Put, NM; Wijermans, PW1
Gérard, M; Ogier de Baulny, H; Saudubray, JM; Zittoun, J1
Fäldt, R; Gustafson, L; Hultberg, B; Nilsson, K; Warkentin, S1
Bagnoli, F; Bellieni, CV; Buonocore, G; Cioni, M; De Felice, C; Farnetani, M; Ferrari, F; Gatti, MG1
Baumgartner, ER; Bosk, A; Fowler, B; Heinemann, MK; Sieverding, L; Tomaske, M; Trefz, FK1
Zittoun, J1
Birke, RL; Yan, L; Zheng, D1
Elian, KM; Hoffer, LJ1
Blom, HJ; Bos, GM; den Heijer, M; Klerk, M; Schouten, EG; Verbruggen, B; Verhoef, P1
Arnout, J; Baumgartner, ER; Fowler, B; Fryns, JP; Grünewald, S; Peters, H; Van Damme, B; Van Damme-Lombaerts, R; Van Hove, JL; Wevers, R1
Blom, HJ; den Heijer, M; Peeters, AC; van der Molen, EF1
Fowler, B; Gutsche, S; Hennermann, JB; Horneff, G; Kozich, V; Mueller, P; Novotna, Z; Suormala, T; Vilarinho, L; Vilaseca, MA; Wilichowski, E; Zavadáková, P; Zeman, J1
Fulton, AB; Hansen, RM; Marsden, DL; Tsina, EK1
Bourgouin, PE; Djahangirian, O; Eid, J; Hoffer, LJ; Saboohi, F1
Jakobs, C; Kok, RM; Smith, DE; Smulders, YM; Stehouwer, CD; Swinkels, DW; Teerlink, T1
Campbell, CD; Ficicioglu, C; Ganesh, J1
DiBello, PM; Hannibal, L; Jacobsen, DW; Miller, A; Rosenblatt, DS; Wang, S; Willard, B; Yu, M1
Liu, YP; Yang, YL1
Bjørke-Monsen, AL; Markestad, T; Torsvik, I; Ueland, PM1
Benoist, JF; Cornec-Le Gall, E; De Parscau, L; Delmas, Y; Doucet, L; Fremeaux-Bacchi, V; Le Meur, Y; Ogier, H1
Harrington, D; Hunt, A; Robinson, S1
Baumgartner, M; Beck, BB; Bockmeyer, C; Koenig, JC; Konrad, M; Kranz, B; Rutsch, F1
Joshi, K; Kumbar, V; Mishra, S; Otiv, S; Shah, T1
Mazokopakis, EE1
Florindo, C; Gaspar, A; Janeiro, P; Lipari Pinto, P; Mexia, S; Rocha, H; Santos, RL; Tavares de Almeida, I; Vilarinho, L1

Reviews

4 review(s) available for homocysteine and hydroxocobalamin

ArticleYear
Remethylation defects: guidelines for clinical diagnosis and treatment.
    European journal of pediatrics, 1998, Volume: 157 Suppl 2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Betaine; Child, Preschool; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Practice Guidelines as Topic; Vitamin B 12

1998
[Biermer's disease].
    La Revue du praticien, 2001, Sep-15, Volume: 51, Issue:14

    Topics: Anemia, Pernicious; Autoantibodies; Diagnosis, Differential; Hematinics; Homocysteine; Humans; Hydroxocobalamin; Injections, Intramuscular; Prognosis; Risk Factors; Stomach Neoplasms; Vitamin B 12 Deficiency

2001
[Advances in the clinical and laboratory studies on methylmalonic aciduria combined with homocysteinemia type cblC].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2013, Volume: 51, Issue:4

    Topics: Adult; Age of Onset; Amino Acid Metabolism, Inborn Errors; Betaine; Carrier Proteins; Child; China; DNA Mutational Analysis; Gas Chromatography-Mass Spectrometry; Genotype; Homocysteine; Humans; Hydroxocobalamin; Hyperhomocysteinemia; Infant; Methylmalonic Acid; Mutation; Oxidoreductases; Vitamin B 12

2013
Vitamin B12 deficiency.
    BMJ (Clinical research ed.), 2014, Sep-04, Volume: 349

    Topics: Homocysteine; Humans; Hydroxocobalamin; Methylmalonic Acid; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex

2014

Trials

6 trial(s) available for homocysteine and hydroxocobalamin

ArticleYear
Vitamin supplementation reduces blood homocysteine levels: a controlled trial in patients with venous thrombosis and healthy volunteers.
    Arteriosclerosis, thrombosis, and vascular biology, 1998, Volume: 18, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Reference Values; Thrombophlebitis

1998
Hydroxocobalamin reduces hyperhomocysteinemia in end-stage renal disease.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:7

    Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Hyperhomocysteinemia; Injections, Subcutaneous; Kidney Failure, Chronic; Male; Methylmalonic Acid; Middle Aged; Prospective Studies; Renal Dialysis; Treatment Outcome; Vitamin B 12

2002
Effect of homocysteine reduction by B-vitamin supplementation on markers of clotting activation.
    Thrombosis and haemostasis, 2002, Volume: 88, Issue:2

    Topics: Adult; Aged; Antithrombin III; Biomarkers; Blood Coagulation; Dietary Supplements; Female; Fibrin Fibrinogen Degradation Products; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Male; Middle Aged; Peptide Fragments; Peptide Hydrolases; Prothrombin; Pyridoxine; Vitamin B Complex

2002
The effect of homocysteine reduction by B-vitamin supplementation on markers of endothelial dysfunction.
    Thrombosis and haemostasis, 2004, Volume: 92, Issue:5

    Topics: Adult; Aged; Biomarkers; Case-Control Studies; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Humans; Hydroxocobalamin; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Pyridoxine; Tissue Plasminogen Activator; von Willebrand Factor

2004
Comparative effects of hydroxocobalamin and cyanocobalamin on plasma homocysteine concentrations in end-stage renal disease.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:10

    Topics: Cross-Over Studies; Female; Homocysteine; Humans; Hydroxocobalamin; Kidney Failure, Chronic; Male; Vitamin B 12

2005
Cobalamin supplementation improves motor development and regurgitations in infants: results from a randomized intervention study.
    The American journal of clinical nutrition, 2013, Volume: 98, Issue:5

    Topics: Biomarkers; Child Development; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hydroxocobalamin; Infant; Injections, Intramuscular; Linear Models; Male; Methylmalonic Acid; Surveys and Questionnaires; Vitamin B 12 Deficiency; Vomiting

2013

Other Studies

23 other study(ies) available for homocysteine and hydroxocobalamin

ArticleYear
Methylation of mercury compounds by methylcobalamin.
    Biochemistry, 1971, Jul-06, Volume: 10, Issue:14

    Topics: Chemical Phenomena; Chemistry; Chlorides; Chromatography, Gas; Escherichia coli; Homocysteine; Hydroxides; Hydroxocobalamin; Kinetics; Mercaptoethanol; Mercury; Mercury Poisoning; Methylation; Organometallic Compounds; Spectrophotometry; Ultraviolet Rays; Vitamin B 12

1971
Escherichia coli B N 5 -methyltetrahydrofolate-homocysteine cobalamin methyltransferase: gel-filtration behavior of apoenzyme and holoenzymes.
    Biochimica et biophysica acta, 1971, Aug-20, Volume: 242, Issue:2

    Topics: Alkylation; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Dithiothreitol; Drug Stability; Escherichia coli; Folic Acid; Homocysteine; Hydroxocobalamin; Macromolecular Substances; Mathematics; Methylation; Methyltransferases; Molecular Weight; Tritium; Urea; Vitamin B 12

1971
Mechanism of mammalian cobalamin-dependent methionine biosynthesis.
    Biochemistry, 1971, Aug-03, Volume: 10, Issue:16

    Topics: Alkylation; Animals; Carbon Isotopes; Darkness; Dithiothreitol; Electrophoresis, Disc; Enzyme Activation; Flavin Mononucleotide; Folic Acid; Homocysteine; Hydroxocobalamin; Iodides; Kidney; Kinetics; Light; Mathematics; Mercaptoethanol; Methionine; Methylation; Methyltransferases; Models, Biological; Models, Chemical; Oxidation-Reduction; Radiation Effects; S-Adenosylmethionine; Swine; Tritium

1971
Defective metabolism of vitamin B 12 in fibroblasts from children with methylmalonicaciduria.
    Biochemical and biophysical research communications, 1971, Jul-16, Volume: 44, Issue:2

    Topics: Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Cobalt Isotopes; Deoxyadenosines; Enzyme Activation; Fibroblasts; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Male; Malonates; Metabolism, Inborn Errors; Methylation; Methyltransferases; Vitamin B 12

1971
Deranged B 12 metabolism: studies of fibroblasts grown in tissue culture.
    Biochemical medicine, 1970, Volume: 4, Issue:3

    Topics: Amino Acid Metabolism, Inborn Errors; Carbon Dioxide; Carbon Isotopes; Coenzyme A; Fibroblasts; Folic Acid; Glutamates; Homocysteine; Humans; Hydroxocobalamin; Isomerases; L-Serine Dehydratase; Male; Malonates; Methionine; Methyltransferases; Propionates; Skin; Vitamin B 12

1970
Homocystinuria with methylmalonic aciduria: two cases in a sibship.
    Biochemical medicine, 1970, Volume: 4, Issue:5

    Topics: Adolescent; Carbon Isotopes; Child, Preschool; Coenzyme A; Female; Fibroblasts; Folic Acid; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Isomerases; L-Serine Dehydratase; Male; Malonates; Methionine; Methyltransferases; Pedigree; Propionates; Skin; Vitamin B 12

1970
Congenital methylmalonic aciduria--homocystinuria with megaloblastic anemia: observations on response to hydroxocobalamin and on the effect of homocysteine and methionine on the deoxyuridine suppression test.
    Blood, 1980, Volume: 55, Issue:4

    Topics: Anemia, Megaloblastic; Deoxyuridine; DNA; Female; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Malonates; Methionine; Methylmalonic Acid; Myoclonus; Thymidine

1980
Cyanocobalamin [c-lactam] inhibits vitamin B12 and causes cytotoxicity in HL60 cells: methionine protects cells completely.
    Blood, 1997, Jun-15, Volume: 89, Issue:12

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Death; Enzyme Inhibitors; Folic Acid; HL-60 Cells; Homocysteine; Humans; Hydroxocobalamin; Methionine; Methylmalonyl-CoA Mutase; Propionates; Tetrahydrofolates; Vitamin B 12

1997
Treatment of cobalamin deficiency in dementia, evaluated clinically and with cerebral blood flow measurements.
    Aging (Milan, Italy), 2000, Volume: 12, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebrovascular Circulation; Dementia, Vascular; Female; Homocysteine; Humans; Hydroxocobalamin; Injections, Intramuscular; Male; Methylmalonic Acid; Regional Blood Flow; Vitamin B 12 Deficiency

2000
EEG in assessing hydroxycobalamin therapy in neonatal methylmalonic aciduria with homocystinuria.
    Biology of the neonate, 2000, Volume: 78, Issue:4

    Topics: Electroencephalography; Female; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Infant, Newborn; Metabolism, Inborn Errors; Methylmalonic Acid

2000
CblC/D defect combined with haemodynamically highly relevant VSD.
    Journal of inherited metabolic disease, 2001, Volume: 24, Issue:4

    Topics: Female; Folic Acid; Heart Septal Defects, Ventricular; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Infant, Newborn; Lactic Acid; Metabolism, Inborn Errors; Methionine; Methylmalonic Acid

2001
Electrochemical and spectral studies of the reactions of aquocobalamin with nitric oxide and nitrite ion.
    Inorganic chemistry, 2002, May-06, Volume: 41, Issue:9

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anions; Catalysis; Electrochemistry; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Homocysteine; Hydroxocobalamin; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methionine; Molecular Structure; Nitric Oxide; Nitrites; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Vitamin B 12

2002
Cobalamin disorder Cbl-C presenting with late-onset thrombotic microangiopathy.
    American journal of medical genetics, 2002, Aug-01, Volume: 111, Issue:2

    Topics: Age of Onset; Child; Child, Preschool; Female; Hematinics; Hematuria; Hemolysis; Hemolytic-Uremic Syndrome; Homocysteine; Humans; Hydroxocobalamin; Kidney; Male; Methylmalonic Acid; Microcirculation; Proteinuria; Thrombosis; Vitamin B 12 Deficiency

2002
cblE type of homocystinuria due to methionine synthase reductase deficiency: functional correction by minigene expression.
    Human mutation, 2005, Volume: 25, Issue:3

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Substitution; Betaine; Brain; Cell Line, Transformed; Codon, Nonsense; DNA Mutational Analysis; Ferredoxin-NADP Reductase; Fibroblasts; Folic Acid; Genes, Synthetic; Genetic Complementation Test; Genetic Therapy; Haplotypes; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Mutation, Missense; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Recombinant Fusion Proteins; Sequence Deletion; Transfection; White People

2005
Maculopathy and retinal degeneration in cobalamin C methylmalonic aciduria and homocystinuria.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2005, Volume: 123, Issue:8

    Topics: Amino Acid Metabolism, Inborn Errors; Betaine; Cobamides; Female; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Infant; Macula Lutea; Methionine; Methylmalonic Acid; Retina; Retinal Degeneration; Vision, Ocular; Visual Acuity; Vitamin B 12 Deficiency

2005
Cellular folate vitamer distribution during and after correction of vitamin B12 deficiency: a case for the methylfolate trap.
    British journal of haematology, 2006, Volume: 132, Issue:5

    Topics: Chromatography, Liquid; DNA Methylation; Erythrocytes; Folic Acid; Homocysteine; Homozygote; Humans; Hydroxocobalamin; Male; Mass Spectrometry; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency

2006
Two newborns with nutritional vitamin B12 deficiency: challenges in newborn screening for vitamin B12 deficiency.
    Haematologica, 2005, Volume: 90, Issue:12 Suppl

    Topics: Acyl-CoA Dehydrogenase, Long-Chain; Anemia, Pernicious; Autoimmune Diseases; Biomarkers; Carnitine; Citrates; Cystathionine; False Negative Reactions; Female; Gastric Bypass; Heterozygote; Homocysteine; Humans; Hydroxocobalamin; Infant Food; Infant, Newborn; Malabsorption Syndromes; Male; Mass Spectrometry; Maternal-Fetal Exchange; Methylmalonic Acid; Neonatal Screening; Pregnancy; Pregnancy Complications; Vitamin B 12 Deficiency

2005
The MMACHC proteome: hallmarks of functional cobalamin deficiency in humans.
    Molecular genetics and metabolism, 2011, Volume: 103, Issue:3

    Topics: Amino Acid Metabolism, Inborn Errors; Carrier Proteins; Cell Line; Cells, Cultured; Fibroblasts; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Intracellular Space; Metabolic Networks and Pathways; Methylmalonic Acid; Mutation; Oxidoreductases; Phenotype; Proteome; Vimentin; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex

2011
Adult-onset eculizumab-resistant hemolytic uremic syndrome associated with cobalamin C deficiency.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:1

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Antibodies, Monoclonal, Humanized; Betaine; Biopsy; Carrier Proteins; Diagnosis, Differential; Drug Resistance; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Hypertension, Malignant; Immunologic Factors; Kidney; Kidney Function Tests; Leucovorin; Lipotropic Agents; Male; Methionine; Methylmalonic Acid; Mutation; Oxidoreductases; Recurrence; Renal Dialysis; Treatment Outcome; Vitamin B 12 Deficiency; Vitamin B Complex

2014
Nephrotic syndrome and thrombotic microangiopathy caused by cobalamin C deficiency.
    Pediatric nephrology (Berlin, Germany), 2015, Volume: 30, Issue:7

    Topics: Anemia; Angiotensin-Converting Enzyme Inhibitors; Biopsy; Carrier Proteins; Child, Preschool; Homocysteine; Humans; Hydroxocobalamin; Hypertension, Renal; Kidney; Male; Nephrotic Syndrome; Oxidoreductases; Thrombotic Microangiopathies; Vitamin B 12; Vitamin B 12 Deficiency

2015
Molecular and cellular effects of vitamin B12 forms on human trophoblast cells in presence of excessive folate.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Chorionic Gonadotropin, beta Subunit, Human; Cobamides; Cytoprotection; Dietary Supplements; Dose-Response Relationship, Drug; ErbB Receptors; Female; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Malondialdehyde; Pregnancy; Protective Agents; Trophoblasts; Tumor Necrosis Factor-alpha; Vitamin B 12

2016
Normal serum cobalamin levels do not exclude the diagnosis of pernicious anaemia: a case report.
    Family practice, 2020, 02-19, Volume: 37, Issue:1

    Topics: Anemia, Pernicious; Female; Folic Acid Deficiency; Gastritis, Atrophic; Homocysteine; Humans; Hydroxocobalamin; Methylmalonic Acid; Middle Aged; Tetrahydrofolates; Vitamin B 12; Vitamin B Complex

2020
Acquired Vitamin B12 Deficiency in Newborns: Positive Impact on Newborn Health through Early Detection.
    Nutrients, 2022, Oct-20, Volume: 14, Issue:20

    Topics: Biomarkers; Early Diagnosis; Female; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant Health; Infant, Newborn; Male; Methylmalonic Acid; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency

2022