homocysteine and hydrogen sulfide

homocysteine has been researched along with hydrogen sulfide in 111 studies

Research

Studies (111)

TimeframeStudies, this research(%)All Research%
pre-19906 (5.41)18.7374
1990's1 (0.90)18.2507
2000's19 (17.12)29.6817
2010's69 (62.16)24.3611
2020's16 (14.41)2.80

Authors

AuthorsStudies
Naiki, N; Yamagata, S1
Grabski, J; Paszewski, A1
Florentiev, VL; Goryachenkova, EV; Polyakova, LA; Yefremova, LL1
Yamagata, S1
Chatagner, F; Deme, D1
Miller, SL; Van Trump, JE1
Getoff, N; Lubec, G; Solar, S1
Cattaneo, M; Chantarangkul, V; Hoffman, RM; Tan, Y; Tripodi, A1
Arima, K; Asada, T; Eto, K; Kimura, H; Makifuchi, T1
Carson, RJ1
Chen, X; Jhee, KH; Kruger, WD1
Chang, T; Meng, QH; Wang, H; Wang, R; Wu, L; Yan, SK1
Chen, L; Ding, YG; DU, JB; Ingrid, S; Liu, Y; Qi, JG; Tang, CS1
Chan, EC; Fein, H; Liu, TZ; Zhang, X; Zhao, D1
Angayarkanni, N; Barathi, S; Ramakrishnan, S; Vadhana, P1
Chang, L; Du, J; Geng, B; Jiang, H; Tang, C; Yu, F; Zhao, J1
Distrutti, E; Donini, A; Fiorucci, S; Mencarelli, A; Orlandi, S; Renga, B; Santucci, L; Shah, V1
Ma, Z; Sun, NL; Tang, CS; Xi, Y; Yang, SN1
Hoffman, RM; Tan, Y1
Hughes, WM; Kumar, M; Kundu, S; Moshal, KS; Sen, U; Tyagi, N; Tyagi, SC; Vacek, TP1
Cao, K; Jiang, B; Meng, Q; Mu, W; Mustafa, AK; Qi, J; Snyder, SH; Wang, R; Wu, L; Yang, G; Yang, W; Zhang, S1
Huang, H; Jiang, P; Liu, XQ; Yan, Y1
Hwang, SY; O, K; Prathapasinghe, G; Siow, YL; Wu, N; Xu, Z1
Abe, OA; Basu, P; Givvimani, S; Metreveli, N; Passmore, JC; Sen, U; Shah, KS; Tyagi, N; Tyagi, SC1
Nakahara, A; Ozaki, S; Sakaguchi, C; Yoshiya, M1
Chang, T; Liu, J; Untereiner, A; Wu, L1
Nagashima, S; Nakayama, K; Ohara, N; Takehara, T; Yoshida, A; Yoshimura, M; Yoshimura, S1
Kimura, H1
Mishra, PK; Tyagi, N; Tyagi, SC1
Mishra, PK; Sen, U; Tyagi, N; Tyagi, SC1
Abe, O; Gargoum, R; Munjal, C; Qipshidze, N; Sen, U; Tyagi, SC1
Ito, S; Kamo, M; Kato, H; Kezuka, Y; Kunimatsu, K; Tamura, H; Yoshida, Y1
Chen, RQ; He, JQ; Hu, B; Huang, YE; Jiang, ZS; Ren, YK; Shen, XT; Tang, XQ; Xu, JH; Yin, WL1
Beard, RS; Bearden, SE; Pfau, JC1
Abe, OA; Givvimani, S; Lederer, ED; Sen, U; Tyagi, SC1
Cheng, K; Geoghagen, NS; Holt, TG; Jensen, KK; Jin, L; Luo, MJ; Luo, Q; Malkowitz, L; Ni, W; Quan, S; Waters, MG; Zhang, A; Zhou, HH1
Beard, RS; Bearden, SE1
Bada, JL; Callahan, MP; Cleaves, HJ; Dworkin, JP; Glavin, DP; Lazcano, A; Parker, ET1
Chen, RQ; Fang, HR; Huang, YE; Ren, YK; Shen, XT; Tang, XQ; Wang, CY; Zhuang, YY1
Ballou, DP; Banerjee, R; Singh, S1
Badjatia, N; Claassen, J; Connolly, ES; DeRosa, PA; Ducruet, AF; Fernandez, L; Grobelny, BT; Hickman, ZL; Kotchetkov, IS; Lee, K; Mayer, SA; Narula, R; Zacharia, BE1
Ingrosso, D; Lanza, D; Perna, AF; Sepe, I1
Bian, JS; Liu, YH; Lu, M1
Coley, DM; Givvimani, S; Kundu, S; Metreveli, N; Mishra, PK; Qipshidze, N; Sathnur, PB; Sen, U; Tyagi, N; Tyagi, SC1
Choi, SH; Jung, KJ; Kim, HY; Kim, JI; Lee, E; Park, KM1
Faccenda, A; Mutus, B; Wang, J1
Banerjee, R; Yadav, PK1
Han, SJ; Jang, HS; Jung, KJ; Kim, JI; Park, JW; Park, KM1
Givvimani, S; Kalani, A; Kamat, PK; Sathnur, PB; Tyagi, N; Tyagi, SC1
Peng, H; Wang, B; Wang, K1
Li, MH; Li, X; Tang, JP; Tang, XQ; Wang, CY; Wei, HJ; Yang, XF; Zhang, P; Zou, W1
Li, Y; Pan, W; Sun, L; Sun, S; Wang, S; Xie, Y; Zhang, Z1
Olas, B1
Li, MH; Tang, JP; Tang, XQ; Wang, CY; Wang, L; Wei, HJ; Xu, JH; Zhang, P; Zou, W1
Hammers, MD; Pluth, MD1
Amin, MA; Pushpakumar, SB; Sen, U; Tyagi, SC1
Kundu, S; Pushpakumar, S; Sen, U1
Kalani, A; Kamat, PK; Tyagi, N; Tyagi, SC1
Banerjee, R; Chi, YY; DeRatt, BN; Gregory, JF; Kabil, O; Ralat, MA1
Kontek, B; Olas, B1
Kesherwani, V; Mishra, PK; Nandi, SS; Shahshahan, HR; Sharawat, SK1
Givimani, S; Neamtu, D; Rehman, S; Tyagi, SC; Vacek, TP; Yu, S1
Allen, KD; Miller, DV; Perona, JJ; Rauch, BJ; White, RH1
Cirino, G; Di Minno, A; Di Minno, G; Franchini, M; Lupoli, R; Sorrentino, R; Spadarella, G1
Kalani, A; Kamat, PK; Kyles, P; Tyagi, N1
Cao, YJ; Cheng, J; Du, HP; Hu, LF; Li, JJ; Li, Q; Liu, CF; Wang, F; Wang, YL; Xu, XS; You, SJ1
Fujino, H; Horie, S; Matsumoto, K; Murayama, T; Nakamura, H; Nomura, R; Yamane, S; Yanagihara, M1
Bruzzese, L; Condo, J; Deharo, P; Durand-Gorde, JM; Fenouillet, E; Fromonot, J; Guieu, R; Kipson, N; Mottola, G; Ruf, J1
Bouillaut, L; Dancer-Thibonnier, M; Dubois, T; Dupuy, B; Hamiot, A; Martin-Verstraete, I; Monot, M; Soutourina, O1
Banerjee, R; Kabil, O; Yadav, V1
Dong, S; Jin, M; Li, H; Liang, X; Sun, D; Wang, X; Wang, Y; Wu, J; Zhang, W; Zhong, X1
Pushpakumar, S; Sen, U; Tyagi, SC; Weber, GJ1
Andriamihaja, M; Artaud, I; Blachier, F; Castillo, FT; Galardon, E; Hessani, A; Lan, A; Liot, G; Padovani, D; Pilati, C; Sen, S1
Gu, HF; Li, M; Li, MH; Li, X; Tang, XQ; Wei, HJ; Zhang, P; Zou, W1
Ingrosso, D; Perna, AF; Trepiccione, F; Zacchia, M1
Caprnda, M; Hart, JL; Kobyliak, N; Kruzliak, P; Opatrilova, R; Qaradakhi, T; Zulli, A1
Kumar, M; Modi, M; Sandhir, R1
Siow, YL1
Jiang, ZS; Li, X; Liang, XY; Tang, XQ; Tang, YY; Wang, CY; Wei, HJ; Zhang, P; Zou, W1
Gregory, JF; Kent, J; Kožich, V; Kraus, JP; Krijt, J; Křížková, M; Majtan, T; Ralat, MA; Sokolová, J1
Ci, H; Ge, X; Song, W; Tian, G; Zhang, Y1
Koloshko, O; Korda, М; Melnyk, A; Nechiporuk, V; Zaichko, N1
Li, MH; Li, X; Tang, XQ; Tang, YY; Wang, AP; Wang, CY; Wei, HJ; Zhang, P; Zou, W1
Dong, L; Feng, Y; Li, Q; Shi, Y; Wang, C; Xing, P1
Chang, GD; Gu, TJ; Huang, WC; Lee, DY1
Chen, J; Cui, X; Ding, X; Fang, Y; Kuang, Q; Shen, Z; Xue, N1
Cai, H; Hu, Y; Huang, S; Liu, F; Wang, L; Wu, F; Xu, J; Yu, J; Zhou, Y1
Arslanova, AN; Dmitrieva, SA; Giniatullin, RA; Khaertdinov, NN; Minibayeva, FV; Sitdikova, GF; Yakovlev, AV; Yakovleva, OV; Ziganshina, AR; Ziyatdinova, GK1
Chen, W; Huang, C; Huang, J; Sheng, J; Song, X; Xu, L; Zhang, H1
Barroso, M; Castro, R; Esse, R; Tavares de Almeida, I1
Arora, R; Bansal, AK; Bhattacharya, R; Hasan, T; Sharma, GS; Singh, LR1
Bronowicka-Adamska, P; Gawda, A; Jurkowska, H; Marcinkiewicz, J; Nazimek, K; Skalska, P; Wróbel, M1
Behera, J; Tyagi, N; Tyagi, SC; Zhai, Y1
Kumar, M; Sandhir, R2
Chen, J; Hong, X; Jiang, Y; Niu, X; Wang, J; Zhang, D; Zhang, Y1
Kachula, S; Korda, M; Mel'nyk, A; Nechiporuk, V; Pentiuk, N1
Feng, C; Ge, Y; Han, L; Jiang, Y; Le, G; Li, B; Shi, Y; Wu, G; Yang, Y1
Kang, X; Li, C; Tang, XQ; Tang, YY; Xie, X; Yang, SQ; Zhan, KB; Zhang, P; Zou, W1
Huang, P; Huang, S; Lin, Z; Sun, J; Yu, H; Zhong, Y1
Bogatova, K; Gerasimova, E; Hermann, A; Mukhtarova, R; Shakhmatova, V; Sitdikova, G; Yakovlev, A; Yakovleva, O; Ziyatdinova, G1
Astegno, A; Conter, C; Dominici, P; Fernández-Rodríguez, C; Fruncillo, S; Martínez-Cruz, LA1
Stipanuk, MH1
Kožich, V; Stabler, S1
Deharo, P; Fromonot, J; Guieu, R; Marlinge, M; Mottola, G; Paganelli, F; Ruf, J1
Cai, J; Chen, Z; Cui, C; Fan, X; Geng, B; Gong, Y; Jiang, S; Xu, W1
Chauhan, P; Kumaraswamy, A; Ravi, R; Subramaniam Rajesh, B1
Chen, SM; Tang, XQ1
Beltrán, LJ; Bulleid, NJ; Johnstone, IL; Page, AP; Tjahjono, E; Winter, AD1
Podsiadły, R; Romański, J; Świerczyńska, M; Słowiński, D1
Chen, K; Chen, Z; Lai, W; Li, L; Liu, H; Mao, Y; Wang, J; Xi, M; Ye, T; Yu, Q1

Reviews

21 review(s) available for homocysteine and hydrogen sulfide

ArticleYear
[Sulfate reduction and biosynthesis of sulfur containing amino acids (author's transl)].
    Seikagaku. The Journal of Japanese Biochemical Society, 1974, Volume: 46, Issue:3

    Topics: Amino Acids, Sulfur; Bacteria; Cysteine; Feedback; Homocysteine; Hydrogen Sulfide; Methionine; Oxidation-Reduction; Sulfates; Sulfur; Sulfur Acids; Sulfuric Acids; Thiosulfates; Vitamin B 12

1974
Hydrogen sulfide: its production, release and functions.
    Amino acids, 2011, Volume: 41, Issue:1

    Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Homocysteine; Humans; Hydrogen Sulfide; Sulfurtransferases

2011
Homocysteine, hydrogen sulfide (H2S) and NMDA-receptor in heart failure.
    Indian journal of biochemistry & biophysics, 2009, Volume: 46, Issue:6

    Topics: Animals; Gene Deletion; Heart Failure; Homocysteine; Humans; Hydrogen Sulfide; Myocardial Contraction; Receptors, N-Methyl-D-Aspartate

2009
Homocysteine to hydrogen sulfide or hypertension.
    Cell biochemistry and biophysics, 2010, Volume: 57, Issue:2-3

    Topics: Calcium; Collagen; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Hypertension; Muscle, Smooth, Vascular; Nitric Oxide

2010
Vascular complications of cystathionine β-synthase deficiency: future directions for homocysteine-to-hydrogen sulfide research.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:1

    Topics: Animals; Disease Models, Animal; Homocysteine; Homocystinuria; Humans; Hydrogen Sulfide; Mice; Vascular Diseases

2011
Hydrogen sulfide and renal ischemia.
    Expert review of clinical pharmacology, 2011, Volume: 4, Issue:1

    Topics: Animals; Homocysteine; Humans; Hydrogen Sulfide; Ischemia; Kidney; Kidney Diseases; Signal Transduction

2011
Recent advances in thiol and sulfide reactive probes.
    Journal of cellular biochemistry, 2014, Volume: 115, Issue:6

    Topics: Cysteine; Fluorescent Dyes; Glutathione; Homocysteine; Hydrogen Sulfide; Models, Chemical; Molecular Structure; Sulfhydryl Compounds; Sulfides

2014
Hydrogen sulfide in hemostasis: friend or foe?
    Chemico-biological interactions, 2014, Jun-25, Volume: 217

    Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Hemostasis; Homocysteine; Humans; Hydrogen Sulfide; Muscle, Smooth, Vascular; Signal Transduction

2014
Homocysteine in renovascular complications: hydrogen sulfide is a modulator and plausible anaerobic ATP generator.
    Nitric oxide : biology and chemistry, 2014, Sep-15, Volume: 41

    Topics: Adenosine Triphosphate; Anaerobiosis; Animals; Homocysteine; Humans; Hydrogen Sulfide; Kidney; Kidney Diseases; Mice; Rats; Vascular Diseases

2014
Endothelial dysfunction: the link between homocysteine and hydrogen sulfide.
    Current medicinal chemistry, 2014, Volume: 21, Issue:32

    Topics: Homocysteine; Humans; Hydrogen Sulfide; Oxidative Stress

2014
Matrix metalloproteinases in atherosclerosis: role of nitric oxide, hydrogen sulfide, homocysteine, and polymorphisms.
    Vascular health and risk management, 2015, Volume: 11

    Topics: Animals; Atherosclerosis; Blood Vessels; Enzyme Activation; Genetic Predisposition to Disease; Homocysteine; Humans; Hydrogen Sulfide; Matrix Metalloproteinases; Nitric Oxide; Oxidative Stress; Phenotype; Polymorphism, Genetic; Reactive Oxygen Species; Signal Transduction; Vascular Remodeling; Vasodilation

2015
Methylation reactions, the redox balance and atherothrombosis: the search for a link with hydrogen sulfide.
    Seminars in thrombosis and hemostasis, 2015, Volume: 41, Issue:4

    Topics: Animals; Aspirin; Atherosclerosis; Folic Acid; Gasotransmitters; Homocysteine; Humans; Hydrogen Sulfide; Methionine; Methylation; Oxidation-Reduction; Thrombosis

2015
Homocysteine and hydrogen sulfide in epigenetic, metabolic and microbiota related renovascular hypertension.
    Pharmacological research, 2016, Volume: 113, Issue:Pt A

    Topics: Animals; Epigenesis, Genetic; Homocysteine; Humans; Hydrogen Sulfide; Hypertension, Renovascular; Metabolome; Microbiota

2016
The Sulfur Metabolite Lanthionine: Evidence for a Role as a Novel Uremic Toxin.
    Toxins, 2017, 01-10, Volume: 9, Issue:1

    Topics: Alanine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Renal Dialysis; Sulfides; Uremia

2017
Metabolic Imbalance of Homocysteine and Hydrogen Sulfide in Kidney Disease.
    Current medicinal chemistry, 2018, 01-30, Volume: 25, Issue:3

    Topics: Animals; Homocysteine; Humans; Hydrogen Sulfide; Kidney Diseases

2018
The Contribution of Homocysteine Metabolism Disruption to Endothelial Dysfunction: State-of-the-Art.
    International journal of molecular sciences, 2019, Feb-17, Volume: 20, Issue:4

    Topics: Atherosclerosis; Cardiovascular Diseases; Endothelial Cells; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Methionine; Nitric Oxide; Reactive Oxygen Species; S-Adenosylhomocysteine

2019
Disturbed homocysteine metabolism is associated with cancer.
    Experimental & molecular medicine, 2019, 02-21, Volume: 51, Issue:2

    Topics: Alleles; Animals; Cystathionine beta-Synthase; Disease Susceptibility; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Metabolic Networks and Pathways; Neoplasms; Polymorphism, Genetic; Risk Factors; Sulfur; Thromboembolism

2019
Metabolism of Sulfur-Containing Amino Acids: How the Body Copes with Excess Methionine, Cysteine, and Sulfide.
    The Journal of nutrition, 2020, 10-01, Volume: 150, Issue:Suppl 1

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Cystathionine beta-Synthase; Cysteine; Glycine N-Methyltransferase; Homocysteine; Humans; Hydrogen Sulfide; Liver; Methionine; S-Adenosylmethionine; Serine; Sulfides; Sulfur; Thiosulfates

2020
Lessons Learned from Inherited Metabolic Disorders of Sulfur-Containing Amino Acids Metabolism.
    The Journal of nutrition, 2020, 10-01, Volume: 150, Issue:Suppl 1

    Topics: Amino Acids, Sulfur; Animals; Brain Diseases; Cysteine; Glutathione; Homocysteine; Homocystinuria; Humans; Hydrogen Sulfide; Liver; Metabolic Diseases; Metabolism, Inborn Errors; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Sulfites; Sulfur; Sulfur Compounds

2020
Hyperhomocysteinemia and Cardiovascular Disease: Is the Adenosinergic System the Missing Link?
    International journal of molecular sciences, 2021, Feb-08, Volume: 22, Issue:4

    Topics: Animals; Cardiovascular Diseases; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Receptor, Adenosine A2A

2021
Homocysteinylation and Sulfhydration in Diseases.
    Current neuropharmacology, 2022, Aug-03, Volume: 20, Issue:9

    Topics: Homocysteine; Humans; Hydrogen Sulfide

2022

Other Studies

90 other study(ies) available for homocysteine and hydrogen sulfide

ArticleYear
Studies on beta-cystathionase and omicron-acetylhomoserine sulfhydrylase as the enzymes of alternative methionine biosynthetic pathways in Aspergillus nidulans.
    Acta biochimica Polonica, 1973, Volume: 20, Issue:2

    Topics: Acetylation; Aspergillus; Aspergillus nidulans; Cystathionine; Enzyme Repression; Homocysteine; Homoserine; Hydrogen Sulfide; Lyases; Methionine; Serine

1973
Interaction of pyridoxal phosphate analogues with apoenzymes of gamma-cystathionase and serine sulphhydrase.
    Biochemical and biophysical research communications, 1973, Dec-10, Volume: 55, Issue:3

    Topics: Animals; Apoproteins; Binding Sites; Borohydrides; Chickens; Circular Dichroism; Cystathionine; Homocysteine; Hydro-Lyases; Hydrogen Sulfide; Kinetics; Liver; Lyases; Methylation; Penicillamine; Protein Binding; Pyridoxal Phosphate; Rats; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1973
Homocysteine synthesis in yeast. Partial purification and properties of O-acetylhomoserine sulfhydrylase.
    Journal of biochemistry, 1971, Volume: 70, Issue:6

    Topics: Amino Acids; Chromatography, DEAE-Cellulose; Chromatography, Paper; Electrophoresis, Disc; Homocysteine; Homoserine; Hydrogen Sulfide; Hydrogen-Ion Concentration; Kinetics; Lyases; Molecular Weight; Saccharomyces; Saccharomyces cerevisiae

1971
[Active center of rat liver homoserine dehydratase].
    Biochimica et biophysica acta, 1972, Feb-28, Volume: 258, Issue:2

    Topics: Alanine; Animals; Binding Sites; Cystathionine; Cysteine; Deamination; Homocysteine; Homoserine; Hydro-Lyases; Hydrogen Sulfide; Kinetics; Liver; Methionine; Protein Binding; Rats; Stereoisomerism; Structure-Activity Relationship; Sulfhydryl Compounds

1972
Prebiotic synthesis of methionine.
    Science (New York, N.Y.), 1972, Nov-24, Volume: 178, Issue:4063

    Topics: Aldehydes; Aminobutyrates; Ammonia; Glutamates; Homocysteine; Homoserine; Hydrogen Sulfide; Hydrolysis; Methane; Methionine; Nitrogen; Sulfhydryl Compounds; Ultraviolet Rays; Water

1972
Reactivity of homocysteine-thiolactone and alpha-methylhomocysteine-thiolactone with e-(aq) and OH-radical: a pulse radiolysis study.
    Life sciences, 1998, Volume: 63, Issue:16

    Topics: Ammonia; Chromatography, Thin Layer; Electrons; Free Radical Scavengers; Homocysteine; Hydrogen Sulfide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxyl Radical; Kinetics; Protons; Pulse Radiolysis; Radiation-Protective Agents; Radiation, Ionizing

1998
Evaluation of an enzymatic method to measure total homocysteine in plasma.
    Thrombosis and haemostasis, 2002, Volume: 87, Issue:1

    Topics: Blood Preservation; Chromatography, High Pressure Liquid; Cryopreservation; Fasting; Homocysteine; Humans; Hydrogen Sulfide; Hydrolases; Hyperhomocysteinemia; Plasma; Recombinant Proteins; Reproducibility of Results; Sensitivity and Specificity

2002
Brain hydrogen sulfide is severely decreased in Alzheimer's disease.
    Biochemical and biophysical research communications, 2002, May-24, Volume: 293, Issue:5

    Topics: Alzheimer Disease; Amino Acids; Blotting, Western; Brain; Cysteine; Dose-Response Relationship, Drug; Homocysteine; Humans; Hydrogen Sulfide; S-Adenosylmethionine

2002
Don't forget about hydrogen sulphide.
    British journal of biomedical science, 2004, Volume: 61, Issue:3

    Topics: Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Thrombosis

2004
Production of the neuromodulator H2S by cystathionine beta-synthase via the condensation of cysteine and homocysteine.
    The Journal of biological chemistry, 2004, Dec-10, Volume: 279, Issue:50

    Topics: Calcium; Calmodulin; Cystathionine beta-Synthase; Cysteine; Escherichia coli; Homocysteine; Humans; Hydrogen Sulfide; In Vitro Techniques; Kinetics; Neurotransmitter Agents; Recombinant Proteins; Saccharomyces cerevisiae

2004
Effects of hydrogen sulfide on homocysteine-induced oxidative stress in vascular smooth muscle cells.
    Biochemical and biophysical research communications, 2006, Dec-15, Volume: 351, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cell Line; Glutathione; Homocysteine; Hydrogen Sulfide; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Onium Compounds; Oxidative Stress; Rats; Reactive Nitrogen Species; Reactive Oxygen Species; Sulfides; Superoxide Dismutase; Superoxides

2006
Imbalance of endogenous homocysteine and hydrogen sulfide metabolic pathway in essential hypertensive children.
    Chinese medical journal, 2007, Mar-05, Volume: 120, Issue:5

    Topics: Adolescent; Child; Female; Homocysteine; Humans; Hydrogen Sulfide; Hypertension; Male; Systole

2007
A novel enzymatic method for determination of homocysteine using electrochemical hydrogen sulfide sensor.
    Frontiers in bioscience : a journal and virtual library, 2007, May-01, Volume: 12

    Topics: Electrochemistry; Homocysteine; Hydrogen Sulfide; Hydrogen-Ion Concentration; Lyases; Reproducibility of Results; Sensitivity and Specificity

2007
Estimation of hydrogen sulphide in the human lymphocytes.
    Indian journal of biochemistry & biophysics, 2007, Volume: 44, Issue:3

    Topics: Adult; Cysteine; Female; Homocysteine; Humans; Hydrogen Sulfide; Leukocytes, Mononuclear; Lymphocytes; Male; Models, Biological; Models, Chemical; Signal Transduction; Substrate Specificity; Tissue Distribution; Zinc Acetate

2007
Hydrogen sulfide inhibits myocardial injury induced by homocysteine in rats.
    Amino acids, 2008, Volume: 34, Issue:4

    Topics: Animals; Cystathionine gamma-Lyase; Disease Models, Animal; Electron Transport Complex IV; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Activation; Heart Diseases; Heat-Shock Proteins; Homocysteine; Hydrogen Peroxide; Hydrogen Sulfide; Lipid Peroxidation; Male; Mitochondria, Heart; Molecular Chaperones; Myocardium; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Succinate Dehydrogenase; Superoxide Dismutase; Superoxides; Time Factors

2008
The methionine connection: homocysteine and hydrogen sulfide exert opposite effects on hepatic microcirculation in rats.
    Hepatology (Baltimore, Md.), 2008, Volume: 47, Issue:2

    Topics: Acetylcholine; Animals; Disease Models, Animal; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Liver; Liver Circulation; Liver Cirrhosis; Male; Methionine; Microcirculation; Rats; Rats, Wistar

2008
[Plasma hydrogen sulfide and homocysteine levels in hypertensive patients with different blood pressure levels and complications].
    Zhonghua xin xue guan bing za zhi, 2007, Volume: 35, Issue:12

    Topics: Adult; Aged; Blood Pressure; Case-Control Studies; Female; Gases; Homocysteine; Humans; Hydrogen Sulfide; Hypertension; Male; Middle Aged; Plasma

2007
A highly sensitive single-enzyme homocysteine assay.
    Nature protocols, 2008, Volume: 3, Issue:9

    Topics: Blood Chemical Analysis; Fluorescence; Homocysteine; Hydrogen Sulfide; Lyases; Molecular Structure

2008
H2S protects against methionine-induced oxidative stress in brain endothelial cells.
    Antioxidants & redox signaling, 2009, Volume: 11, Issue:1

    Topics: Acetophenones; Acetylcysteine; Animals; Brain; Catalase; Cell Line, Transformed; Cell Survival; Dose-Response Relationship, Drug; Endothelial Cells; Formazans; Glutathione; Homocysteine; Hydrogen Sulfide; Methionine; Mice; Models, Biological; NG-Nitroarginine Methyl Ester; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Time Factors

2009
H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase.
    Science (New York, N.Y.), 2008, Oct-24, Volume: 322, Issue:5901

    Topics: Animals; Aorta; Blood Pressure; Calcium; Calmodulin; Cystathionine gamma-Lyase; Cysteine; Endothelium, Vascular; Homocysteine; Hydrogen Sulfide; Hypertension; Mesenteric Arteries; Methacholine Chloride; Mice; Mice, Knockout; Myocardium; Oxidation-Reduction; Sulfides; Vasodilation

2008
[Plasma levels of endogenous hydrogen sulfide and homocysteine in patients with Alzheimer's disease and vascular dementia and the significance thereof].
    Zhonghua yi xue za zhi, 2008, Aug-19, Volume: 88, Issue:32

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia, Vascular; Female; Homocysteine; Humans; Hydrogen Sulfide; Male; Middle Aged; Psychiatric Status Rating Scales

2008
Ischemia-reperfusion reduces cystathionine-beta-synthase-mediated hydrogen sulfide generation in the kidney.
    American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:1

    Topics: Animals; Apoptosis; Cyclic N-Oxides; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Disease Models, Animal; Free Radical Scavengers; Homeostasis; Homocysteine; Hydrogen Sulfide; Imidazoles; Kidney; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2009
Hydrogen sulfide ameliorates hyperhomocysteinemia-associated chronic renal failure.
    American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:2

    Topics: Animals; Antioxidants; Apoptosis; Cystathionine beta-Synthase; Desmin; Disease Models, Animal; Glutathione; Glutathione Disulfide; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Kidney; Kidney Failure, Chronic; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; Oxidative Stress; Proteinuria; Sulfides; Superoxides

2009
Mutagenesis studies of human cystathionine beta-synthase: residues important for heme binding and substrate interactions.
    Protein and peptide letters, 2010, Volume: 17, Issue:3

    Topics: Catalytic Domain; Cystathionine beta-Synthase; Heme; Homocysteine; Humans; Hydrogen Sulfide; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Serine; Spectrophotometry; Structure-Activity Relationship

2010
Interaction of methylglyoxal and hydrogen sulfide in rat vascular smooth muscle cells.
    Antioxidants & redox signaling, 2010, May-01, Volume: 12, Issue:9

    Topics: Animals; Cell Line; Cysteine; Dose-Response Relationship, Drug; Glutathione; Homocysteine; Hydrogen Sulfide; Lyases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pyruvaldehyde; Rats; Reactive Oxygen Species; Time Factors

2010
Hydrogen sulfide production from cysteine and homocysteine by periodontal and oral bacteria.
    Journal of periodontology, 2009, Volume: 80, Issue:11

    Topics: Adult; Aged; Bacteria; Bacteroides; Bismuth; Carbon-Sulfur Lyases; Chlorides; Cysteine; Dental Plaque; Enterococcus; Female; Fusobacterium nucleatum; Homocysteine; Humans; Hydrogen Sulfide; Indicators and Reagents; Male; Middle Aged; Mouth; Periodontal Diseases; Periodontal Pocket; Porphyromonas gingivalis; Prevotella intermedia; Prevotella nigrescens; Streptococcus; Streptococcus anginosus

2009
Hydrogen sulfide regulates homocysteine-mediated glomerulosclerosis.
    American journal of nephrology, 2010, Volume: 31, Issue:5

    Topics: Animals; Collagen; Cystathionine beta-Synthase; Down-Regulation; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Inflammation; Kidney; Kidney Diseases; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL

2010
Production of hydrogen sulfide by two enzymes associated with biosynthesis of homocysteine and lanthionine in Fusobacterium nucleatum subsp. nucleatum ATCC 25586.
    Microbiology (Reading, England), 2010, Volume: 156, Issue:Pt 7

    Topics: Alanine; Ammonia; Aspartate Aminotransferases; Bacterial Proteins; Cysteine Synthase; Fusobacterium nucleatum; Homocysteine; Hydrogen Sulfide; Kinetics; Pyruvic Acid; Substrate Specificity; Sulfides

2010
Hydrogen sulfide antagonizes homocysteine-induced neurotoxicity in PC12 cells.
    Neuroscience research, 2010, Volume: 68, Issue:3

    Topics: Analysis of Variance; Animals; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Cytoprotection; Flow Cytometry; Homocysteine; Hydrogen Sulfide; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species

2010
Extracellular transsulfuration generates hydrogen sulfide from homocysteine and protects endothelium from redox stress.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 299, Issue:5

    Topics: Adolescent; Adult; Aged; Animals; Cells, Cultured; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Endothelium, Vascular; Hepatocytes; Homocysteine; Humans; Hydrogen Sulfide; Mice; Mice, Inbred C57BL; Middle Aged; Models, Animal; Oxidation-Reduction; Oxidative Stress; Young Adult

2010
Cystathionine β-synthase and cystathionine γ-lyase double gene transfer ameliorate homocysteine-mediated mesangial inflammation through hydrogen sulfide generation.
    American journal of physiology. Cell physiology, 2011, Volume: 300, Issue:1

    Topics: Animals; Cells, Cultured; Chemokine CCL2; Chemokine CXCL2; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Homocysteine; Hydrogen Sulfide; Inflammation; JNK Mitogen-Activated Protein Kinases; Mesangial Cells; Mice; Signal Transduction

2011
Pharmacological activation and genetic manipulation of cystathionine beta-synthase alter circulating levels of homocysteine and hydrogen sulfide in mice.
    European journal of pharmacology, 2011, Jan-10, Volume: 650, Issue:1

    Topics: Adenoviridae; Animals; Cystathionine beta-Synthase; Enzyme Activation; Genetic Engineering; Homocysteine; Humans; Hydrogen Sulfide; Male; Mice; Mice, Inbred C57BL; Mutation; Recombinant Proteins; S-Adenosylmethionine

2011
Prebiotic synthesis of methionine and other sulfur-containing organic compounds on the primitive Earth: a contemporary reassessment based on an unpublished 1958 Stanley Miller experiment.
    Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 2011, Volume: 41, Issue:3

    Topics: Ammonia; Carbon Dioxide; Chromatography, High Pressure Liquid; Cysteamine; Cysteine; Electricity; History, 20th Century; Homocysteine; Hydrogen Sulfide; Methane; Methionine; Sulfur Compounds; Ultraviolet Rays

2011
Inhibition of endogenous hydrogen sulfide generation is associated with homocysteine-induced neurotoxicity: role of ERK1/2 activation.
    Journal of molecular neuroscience : MN, 2011, Volume: 45, Issue:1

    Topics: Animals; Antioxidants; Cystathionine beta-Synthase; Enzyme Activation; Homocysteine; Hydrogen Sulfide; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurotoxicity Syndromes; PC12 Cells; Rats; Reactive Oxygen Species

2011
Pre-steady-state kinetic analysis of enzyme-monitored turnover during cystathionine β-synthase-catalyzed H(2)S generation.
    Biochemistry, 2011, Jan-25, Volume: 50, Issue:3

    Topics: Cystathionine; Cystathionine beta-Synthase; Cysteine; Homocysteine; Hydrogen Sulfide; Kinetics; Models, Chemical; Protein Conformation; Saccharomyces cerevisiae Proteins

2011
Gain-of-function polymorphisms of cystathionine β-synthase and delayed cerebral ischemia following aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2011, Volume: 115, Issue:1

    Topics: Aged; Brain Ischemia; Cystathionine beta-Synthase; Female; Genetic Predisposition to Disease; Homocysteine; Humans; Hydrogen Sulfide; Male; Middle Aged; Polymorphism, Single Nucleotide; Prospective Studies; Risk Factors; Subarachnoid Hemorrhage; Time Factors; Vasospasm, Intracranial

2011
Hydrogen sulfide increases after a single hemodialysis session.
    Kidney international, 2011, Volume: 80, Issue:10

    Topics: Biomarkers; Cystathionine gamma-Lyase; Homeostasis; Homocysteine; Humans; Hydrogen Sulfide; Renal Dialysis; Up-Regulation

2011
Increased endogenous H2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia.
    American journal of physiology. Cell physiology, 2012, Jul-01, Volume: 303, Issue:1

    Topics: Animals; Cells, Cultured; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Endostatins; Forkhead Box Protein O3; Forkhead Transcription Factors; Genetic Therapy; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Hypertension, Renovascular; Matrix Metalloproteinase 13; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Platelet Endothelial Cell Adhesion Molecule-1; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Renal Artery; Sulfurtransferases; Tissue Inhibitor of Metalloproteinase-1; Vascular Endothelial Growth Factor A; Vascular System Injuries

2012
Protective role of methionine sulfoxide reductase A against ischemia/reperfusion injury in mouse kidney and its involvement in the regulation of trans-sulfuration pathway.
    Antioxidants & redox signaling, 2013, Jun-10, Volume: 18, Issue:17

    Topics: Animals; Antigens, Ly; Disease Models, Animal; Enzyme Activation; Gene Deletion; Gene Expression Regulation; Homocysteine; Hydrogen Sulfide; Inflammation; Kidney; Male; Methionine Sulfoxide Reductases; Mice; Mice, Knockout; Oxidative Stress; Reperfusion Injury

2013
Polydimethylsiloxane permeability-based method for the continuous and specific detection of hydrogen sulfide.
    Analytical chemistry, 2012, Jun-19, Volume: 84, Issue:12

    Topics: Cystathionine gamma-Lyase; Cysteine; Dimethylpolysiloxanes; Homocysteine; Humans; Hydrogen Sulfide; Hydrogen-Ion Concentration; Limit of Detection; Membranes, Artificial; Nitric Oxide; Oxygen; Permeability; Reproducibility of Results; Time Factors

2012
Detection of reaction intermediates during human cystathionine β-synthase-monitored turnover and H2S production.
    The Journal of biological chemistry, 2012, Dec-21, Volume: 287, Issue:52

    Topics: Cystathionine beta-Synthase; Cysteine; Heme; Homocysteine; Humans; Hydrogen Sulfide; Kinetics; Serine

2012
Involvement of hydrogen sulfide and homocysteine transsulfuration pathway in the progression of kidney fibrosis after ureteral obstruction.
    Biochimica et biophysica acta, 2013, Volume: 1832, Issue:12

    Topics: Animals; Blood Pressure; Blotting, Western; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Disease Progression; Fibrosis; Glutathione; Homocysteine; Hydrogen Peroxide; Hydrogen Sulfide; Immunoenzyme Techniques; Kidney Diseases; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Signal Transduction; Sulfides; Superoxide Dismutase; Superoxides; Transforming Growth Factor beta1; Ureteral Obstruction

2013
Hydrogen sulfide attenuates neurodegeneration and neurovascular dysfunction induced by intracerebral-administered homocysteine in mice.
    Neuroscience, 2013, Nov-12, Volume: 252

    Topics: Animals; Blood-Brain Barrier; Blotting, Western; Brain; Gasotransmitters; Homocysteine; Hydrogen Sulfide; Inflammation; Injections, Intraventricular; Male; Mice; Nerve Degeneration; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction

2013
Disturbance of endogenous hydrogen sulfide generation and endoplasmic reticulum stress in hippocampus are involved in homocysteine-induced defect in learning and memory of rats.
    Behavioural brain research, 2014, Apr-01, Volume: 262

    Topics: Animals; Cystathionine beta-Synthase; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Hippocampus; Homocysteine; Hydrogen Sulfide; Infusions, Intraventricular; Male; Maze Learning; Memory; Rats; Rats, Sprague-Dawley; Recognition, Psychology

2014
Potential biomarkers predicting risk of pulmonary hypertension in congenital heart disease: the role of homocysteine and hydrogen sulfide.
    Chinese medical journal, 2014, Volume: 127, Issue:5

    Topics: Biomarkers; Child; Child, Preschool; Female; Heart Defects, Congenital; Homocysteine; Humans; Hydrogen Sulfide; Hypertension, Pulmonary; Infant; Infant, Newborn; Male; Prospective Studies

2014
Hydrogen sulfide inhibits homocysteine-induced endoplasmic reticulum stress and neuronal apoptosis in rat hippocampus via upregulation of the BDNF-TrkB pathway.
    Acta pharmacologica Sinica, 2014, Volume: 35, Issue:6

    Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Line; Endoplasmic Reticulum Stress; Hippocampus; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Male; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptor, trkB; Signal Transduction; Up-Regulation

2014
Ratiometric measurement of hydrogen sulfide and cysteine/homocysteine ratios using a dual-fluorophore fragmentation strategy.
    Analytical chemistry, 2014, Jul-15, Volume: 86, Issue:14

    Topics: 4-Chloro-7-nitrobenzofurazan; Chemistry Techniques, Analytical; Coumarins; Cysteine; Fluorescent Dyes; Homocysteine; Hydrogen Sulfide; Hymecromone; Oxadiazoles; Oxidation-Reduction; Spectrometry, Fluorescence

2014
Hydrogen Sulfide Epigenetically Attenuates Homocysteine-Induced Mitochondrial Toxicity Mediated Through NMDA Receptor in Mouse Brain Endothelial (bEnd3) Cells.
    Journal of cellular physiology, 2015, Volume: 230, Issue:2

    Topics: Animals; Brain; Endothelial Cells; Epigenesis, Genetic; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondria, Heart; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Signal Transduction

2015
Vitamin B-6 restriction reduces the production of hydrogen sulfide and its biomarkers by the transsulfuration pathway in cultured human hepatoma cells.
    The Journal of nutrition, 2014, Volume: 144, Issue:10

    Topics: Alanine; Biomarkers; Carcinoma, Hepatocellular; Cysteine; Hep G2 Cells; Homocysteine; Humans; Hydrogen Sulfide; Linear Models; Liver Neoplasms; Pyridoxal Phosphate; Sulfides; Vitamin B 6; Vitamin B 6 Deficiency

2014
Hydrogen sulfide decreases the plasma lipid peroxidation induced by homocysteine and its thiolactone.
    Molecular and cellular biochemistry, 2015, Volume: 404, Issue:1-2

    Topics: Blood Coagulation; Blood Platelets; Fibrinolysis; Homocysteine; Humans; Hydrogen Sulfide; Lipid Peroxidation; Lipids; Superoxides

2015
Hydrogen sulfide mitigates homocysteine-mediated pathological remodeling by inducing miR-133a in cardiomyocytes.
    Molecular and cellular biochemistry, 2015, Volume: 404, Issue:1-2

    Topics: Animals; Gene Expression Regulation; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; MEF2 Transcription Factors; Mice; MicroRNAs; Myocytes, Cardiac; Ventricular Remodeling

2015
Homocysteine is biosynthesized from aspartate semialdehyde and hydrogen sulfide in methanogenic archaea.
    Biochemistry, 2015, May-26, Volume: 54, Issue:20

    Topics: Aspartic Acid; Biosynthetic Pathways; Genes, Archaeal; Homocysteine; Hydrogen Sulfide; Methanococcus

2015
Hydrogen Sulfide Ameliorates Homocysteine-Induced Alzheimer's Disease-Like Pathology, Blood-Brain Barrier Disruption, and Synaptic Disorder.
    Molecular neurobiology, 2016, Volume: 53, Issue:4

    Topics: Alzheimer Disease; Animals; Antigens, CD; Avoidance Learning; Blood-Brain Barrier; Cadherins; Cerebrovascular Circulation; Claudin-5; Cystathionine beta-Synthase; Dizocilpine Maleate; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Homocysteine; Hydrogen Sulfide; Intercellular Adhesion Molecule-1; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Memory; Mice, Inbred C57BL; Microtubule-Associated Proteins; Microvessels; Nerve Tissue Proteins; Permeability; RNA, Messenger; Synapses

2016
Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter.
    International journal of molecular sciences, 2015, Jun-03, Volume: 16, Issue:6

    Topics: Animals; Cells, Cultured; Cystathionine gamma-Lyase; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Expression Regulation; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Inflammation Mediators; Macrophages; Male; Methionine; Mice; Morpholines; Organothiophosphorus Compounds; Promoter Regions, Genetic; Signal Transduction

2015
L-Cysteine/D,L-homocysteine-regulated ileum motility via system L and B°(,+) transporter: Modification by inhibitors of hydrogen sulfide synthesis and dietary treatments.
    European journal of pharmacology, 2015, Oct-05, Volume: 764

    Topics: Amino Acid Transport System y+L; Amino Acid Transport Systems, Neutral; Amino Acids, Cyclic; Animals; Cysteine; Diet; Eating; Electric Stimulation; Fasting; Gastrointestinal Motility; Homocysteine; Hydrogen Sulfide; Ileum; In Vitro Techniques; Male; Mice; PC12 Cells; Postprandial Period; Rats; Time Factors

2015
High homocysteine levels prevent via H2 S the CoCl2 -induced alteration of lymphocyte viability.
    Journal of cellular and molecular medicine, 2016, Volume: 20, Issue:8

    Topics: Adenosine; Adult; Alkynes; Cell Hypoxia; Cell Survival; Cobalt; Glycine; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Lymphocytes; Middle Aged; Models, Biological; Signal Transduction

2016
Control of Clostridium difficile Physiopathology in Response to Cysteine Availability.
    Infection and immunity, 2016, Volume: 84, Issue:8

    Topics: Amino Acids; Animals; Bacterial Toxins; Cell Line; Chlorocebus aethiops; Clostridioides difficile; Cysteine; Energy Metabolism; Enterocolitis, Pseudomembranous; Gene Expression Regulation, Bacterial; Homocysteine; Hydrogen Sulfide; Intracellular Space; Metabolic Networks and Pathways; Pyruvic Acid; Vero Cells

2016
Heme-dependent Metabolite Switching Regulates H2S Synthesis in Response to Endoplasmic Reticulum (ER) Stress.
    The Journal of biological chemistry, 2016, 08-05, Volume: 291, Issue:32

    Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Endoplasmic Reticulum Stress; Gene Expression Regulation, Enzymologic; HEK293 Cells; Heme; Heme Oxygenase-1; Homocysteine; Humans; Hydrogen Sulfide; Membrane Proteins; Mice; Mice, Knockout; Signal Transduction; Up-Regulation

2016
Inhibition of hydrogen sulfide on the proliferation of vascular smooth muscle cells involved in the modulation of calcium sensing receptor in high homocysteine.
    Experimental cell research, 2016, 09-10, Volume: 347, Issue:1

    Topics: Adolescent; Animals; Bromodeoxyuridine; Calcium; Calmodulin; Cell Movement; Cell Proliferation; Cell Survival; Cystathionine gamma-Lyase; Homocysteine; Humans; Hydrogen Sulfide; Indoles; Inositol 1,4,5-Trisphosphate; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Naphthalenes; Phenotype; Rats; Receptors, Calcium-Sensing; Signal Transduction; Type C Phospholipases

2016
Sulfheme formation during homocysteine S-oxygenation by catalase in cancers and neurodegenerative diseases.
    Nature communications, 2016, 11-16, Volume: 7

    Topics: Animals; Catalase; Cell Line, Tumor; Chromatography, High Pressure Liquid; Enzyme Activation; Heme; Homocysteine; Hydrogen Sulfide; Iron; Male; Mass Spectrometry; Mice, Inbred C57BL; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Oxygen; Sulfhydryl Compounds

2016
Hydrogen Sulfide Ameliorates Homocysteine-Induced Cognitive Dysfunction by Inhibition of Reactive Aldehydes Involving Upregulation of ALDH2.
    The international journal of neuropsychopharmacology, 2017, 04-01, Volume: 20, Issue:4

    Topics: Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Animals; Cognition Disorders; Disease Models, Animal; Gasotransmitters; Glutathione; Hippocampus; Homocysteine; Hydrogen Sulfide; Injections, Intraventricular; Male; Maze Learning; Quinolines; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Spatial Navigation; Thiazolidinediones; Up-Regulation

2017
H
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 89

    Topics: Acetylcholine; Animals; Arteries; Atherosclerosis; Homocysteine; Hydrogen Sulfide; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Donors; Rabbits; Sulfides; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2017
Hydrogen sulfide attenuates homocysteine-induced cognitive deficits and neurochemical alterations by improving endogenous hydrogen sulfide levels.
    BioFactors (Oxford, England), 2017, May-06, Volume: 43, Issue:3

    Topics: Animals; Cerebral Cortex; Cognition; Cognitive Dysfunction; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Dopamine; Epinephrine; Gene Expression; Hippocampus; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Injections, Subcutaneous; Locomotion; Male; Maze Learning; Monoamine Oxidase; Norepinephrine; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Serotonin; Sulfides

2017
Hydrogen sulfide prevents homocysteine‑induced endoplasmic reticulum stress in PC12 cells by upregulating SIRT‑1.
    Molecular medicine reports, 2017, Volume: 16, Issue:3

    Topics: Animals; Benzamides; Caspase 12; Cytoprotection; Endoplasmic Reticulum Stress; Homocysteine; HSP70 Heat-Shock Proteins; Hydrogen Sulfide; Membrane Proteins; Naphthols; PC12 Cells; Rats; Sirtuin 1; Up-Regulation

2017
Biogenesis of Hydrogen Sulfide and Thioethers by Cystathionine Beta-Synthase.
    Antioxidants & redox signaling, 2018, 02-01, Volume: 28, Issue:4

    Topics: Alanine; Animals; Biomarkers; Catalysis; Cystathionine beta-Synthase; Cysteine; Haplorhini; Homocysteine; Hydrogen Sulfide; Kinetics; Mice; Mice, Knockout; Serine; Sulfides; Sulfur

2018
Edoxaban improves venous thrombosis via increasing hydrogen sulfide and homocysteine in rat model.
    Molecular medicine reports, 2017, Volume: 16, Issue:5

    Topics: Animals; Anticoagulants; Chlorides; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelial Cells; Ferric Compounds; Gene Expression Regulation; Homocysteine; Hydrogen Sulfide; Male; Matrix Metalloproteinase 9; Phosphatidylinositol 3-Kinases; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiazoles; Venous Thrombosis

2017
SULPHUR-CONTAINING AMINO ACIDS METABOLISM IN EXPERIMENTAL HYPER- AND HYPOTHYROIDISM IN RATS.
    Georgian medical news, 2017, Issue:271

    Topics: Adenosylhomocysteinase; Amino Acids, Sulfur; Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Homocysteine; Hydrogen Sulfide; Hyperthyroidism; Hypothyroidism; Kidney; Liver; Male; Methionine Adenosyltransferase; Methylation; Rats; Transaminases

2017
Role of silent information regulator 1 in the protective effect of hydrogen sulfide on homocysteine-induced cognitive dysfunction: Involving reduction of hippocampal ER stress.
    Behavioural brain research, 2018, 04-16, Volume: 342

    Topics: Animals; Cognitive Dysfunction; Endoplasmic Reticulum Stress; Hippocampus; Homocysteine; Hydrogen Sulfide; Male; Memory; Rats; Rats, Sprague-Dawley; Sirtuin 1; Temporal Lobe; Up-Regulation

2018
An ortho-aldehyde modified probe to image thiols in living cells with enhanced selectivity.
    Talanta, 2018, Mar-01, Volume: 179

    Topics: Aldehydes; Buffers; Cysteine; Fluorescent Dyes; Glutathione; HeLa Cells; Homocysteine; Humans; Hydrogen Sulfide; Hydroxyquinolines; Optical Imaging

2018
Quantitative and comparative liquid chromatography-electrospray ionization-mass spectrometry analyses of hydrogen sulfide and thiol metabolites derivaitized with 2-iodoacetanilide isotopologues.
    Journal of chromatography. A, 2018, Jun-01, Volume: 1552

    Topics: Acetanilides; Carbon Isotopes; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Hep G2 Cells; Homocysteine; Humans; Hydrogen Sulfide; Isotope Labeling; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds

2018
Low Plasma Hydrogen Sulfide Is Associated with Impaired Renal Function and Cardiac Dysfunction.
    American journal of nephrology, 2018, Volume: 47, Issue:5

    Topics: Adult; Aged; Biomarkers; Disease Progression; Echocardiography; Female; Glomerular Filtration Rate; Heart Diseases; Homocysteine; Humans; Hydrogen Sulfide; Kidney; Male; Middle Aged; Renal Insufficiency, Chronic

2018
A pharmacological probe identifies cystathionine β-synthase as a new negative regulator for ferroptosis.
    Cell death & disease, 2018, 09-26, Volume: 9, Issue:10

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Proliferation; Cystathionine beta-Synthase; Female; HCT116 Cells; HEK293 Cells; Hep G2 Cells; Homocysteine; Humans; Hydrogen Sulfide; Liver Neoplasms; Mice; Mice, Inbred ICR; Rats

2018
Hydrogen Sulfide Ameliorates Developmental Impairments of Rat Offspring with Prenatal Hyperhomocysteinemia.
    Oxidative medicine and cellular longevity, 2018, Volume: 2018

    Topics: Animals; Antioxidants; Brain; Female; Glutathione Peroxidase; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Lipid Peroxidation; Locomotion; Malondialdehyde; Pregnancy; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Sulfides; Superoxide Dismutase

2018
Simultaneous Discrimination of Cysteine, Homocysteine, Glutathione, and H
    Analytical chemistry, 2019, 02-05, Volume: 91, Issue:3

    Topics: Cysteine; Fluorescent Dyes; Glutathione; HeLa Cells; Homocysteine; Humans; Hydrogen Sulfide; Molecular Structure; Optical Imaging; Signal Transduction

2019
Expression and activity of hydrogen sulfide generating enzymes in murine macrophages stimulated with lipopolysaccharide and interferon-γ.
    Molecular biology reports, 2019, Volume: 46, Issue:3

    Topics: Animals; Cell Line; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Homocysteine; Hydrogen Sulfide; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Sulfurtransferases

2019
Hydrogen sulfide attenuates homocysteine-induced osteoblast dysfunction by inhibiting mitochondrial toxicity.
    Journal of cellular physiology, 2019, Volume: 234, Issue:10

    Topics: Animals; Apoptosis; Calcification, Physiologic; Cell Line; Cell Survival; Homocysteine; Hydrogen Sulfide; Mice, Inbred C57BL; Mitochondria; Osteoblasts; Osteogenesis; Oxidative Stress; Reactive Oxygen Species

2019
Hydrogen sulfide suppresses homocysteine-induced glial activation and inflammatory response.
    Nitric oxide : biology and chemistry, 2019, 09-01, Volume: 90

    Topics: Animals; Homocysteine; Hydrogen Sulfide; Inflammation; Male; Neuroglia; Rats; Rats, Sprague-Dawley

2019
Estradiol-17β inhibits homocysteine mediated damage by promoting H
    Journal of cellular biochemistry, 2021, Volume: 122, Issue:9

    Topics: Case-Control Studies; Cystathionine beta-Synthase; Estradiol; Estrogens; Female; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Sulfide; Sulfides

2021
INFLUENCE OF CHRONIC HYPERHOMOCYSTEINEMIA ON METABOLISM OF SULFUR CONTAINING AMINO ACIDS IN THE RATS' HEART AND BRAIN ON THE BACKGROUND OF HYPERTHYREOSIS AND HYPOTHYREOSIS.
    Georgian medical news, 2019, Issue:295

    Topics: Amino Acids; Animals; Brain; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Male; Myocardium; Sulfur

2019
Dietary methionine restriction improves the impairment of cardiac function in middle-aged obese mice.
    Food & function, 2020, Feb-26, Volume: 11, Issue:2

    Topics: Animals; Body Weight; Cardiomegaly; Diet; Energy Metabolism; Homocysteine; Hydrogen Sulfide; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Obese; Myocardium; Obesity; Oxidative Stress

2020
Hydrogen Sulfide Inhibits Homocysteine-Induced Neuronal Senescence by Up-Regulation of SIRT1.
    International journal of medical sciences, 2020, Volume: 17, Issue:3

    Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Cellular Senescence; Flow Cytometry; Homocysteine; Humans; Hydrogen Sulfide; Neurons; Sirtuin 1

2020
Analysis of Plasma Hydrogen Sulfide, Homocysteine, and L-Cysteine in Open-Angle Glaucoma Patients.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2020, Volume: 36, Issue:8

    Topics: Adult; Aged; Area Under Curve; Case-Control Studies; China; Cysteine; Fasting; Female; Glaucoma; Glaucoma, Open-Angle; Homocysteine; Humans; Hydrogen Sulfide; Low Tension Glaucoma; Male; Middle Aged; Ocular Hypertension

2020
Hydrogen Sulfide Alleviates Anxiety, Motor, and Cognitive Dysfunctions in Rats with Maternal Hyperhomocysteinemia via Mitigation of Oxidative Stress.
    Biomolecules, 2020, 07-02, Volume: 10, Issue:7

    Topics: Animals; Anxiety; Cognitive Dysfunction; Cystathionine beta-Synthase; Female; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Male; Oxidative Stress; Pregnancy; Pregnancy Complications; Rats; Reactive Oxygen Species; Treatment Outcome

2020
Cystathionine β-synthase is involved in cysteine biosynthesis and H
    Scientific reports, 2020, 09-04, Volume: 10, Issue:1

    Topics: Biocatalysis; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; DNA, Complementary; Genes, Protozoan; Heme; Homocysteine; Hydrogen Sulfide; Kinetics; Serine; Toxoplasma

2020
Hydrogen sulfide attenuates hyperhomocysteinemia-induced blood-brain barrier permeability by inhibiting MMP-9.
    The International journal of neuroscience, 2022, Volume: 132, Issue:11

    Topics: Animals; Blood-Brain Barrier; Coloring Agents; Evans Blue; Fluorescein; Gelatin; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Matrix Metalloproteinase 9; Permeability; RNA, Messenger; Sodium; Water

2022
Hydrogen sulphide reduces hyperhomocysteinaemia-induced endothelial ER stress by sulfhydrating protein disulphide isomerase to attenuate atherosclerosis.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:7

    Topics: Animals; Atherosclerosis; Cell Line; Disease Models, Animal; Endoplasmic Reticulum Stress; Endothelial Cells; HEK293 Cells; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Male; Mice; Mice, Knockout, ApoE; Protein Disulfide-Isomerases; Up-Regulation

2021
Exogenous administration of hydrogen sulfide alleviates homocysteine induced inflammation in ARPE-19 cells.
    Experimental eye research, 2021, Volume: 212

    Topics: Animals; Cells, Cultured; Cystathionine beta-Synthase; Gene Expression Regulation; Homocysteine; Hydrogen Sulfide; Inflammation; Retinitis; Signal Transduction

2021
Dietary-derived vitamin B12 protects Caenorhabditis elegans from thiol-reducing agents.
    BMC biology, 2022, 10-08, Volume: 20, Issue:1

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Caenorhabditis elegans; Carbon; Dithiothreitol; Folic Acid; Homocysteine; Hydrogen Sulfide; Ligases; Lipids; Mercaptoethanol; Methionine; Methyltransferases; Nucleic Acids; Oxygen; Reducing Agents; S-Adenosylmethionine; Sulfhydryl Compounds; Vitamin B 12; Vitamins

2022
HPLC Study of Product Formed in the Reaction of NBD-Derived Fluorescent Probe with Hydrogen Sulfide, Cysteine,
    Molecules (Basel, Switzerland), 2022, Nov-28, Volume: 27, Issue:23

    Topics: Acetylcysteine; Cysteine; Fluorescent Dyes; Glutathione; HeLa Cells; Homocysteine; Humans; Hydrogen Sulfide; Optical Imaging; Sulfhydryl Compounds

2022
New Rhodamine-based sensor for high-sensitivity fluorescence tracking of Cys and simultaneously colorimetric detection of H
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2024, Feb-05, Volume: 306

    Topics: Colorimetry; Cysteine; Fluorescent Dyes; Glutathione; HeLa Cells; Homocysteine; Humans; Hydrogen Sulfide; Rhodamines; Spectrometry, Fluorescence; Sulfhydryl Compounds

2024