homocysteine has been researched along with dizocilpine maleate in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.13) | 18.7374 |
| 1990's | 9 (28.13) | 18.2507 |
| 2000's | 6 (18.75) | 29.6817 |
| 2010's | 14 (43.75) | 24.3611 |
| 2020's | 2 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Beal, MF; Ferrante, RJ; Kowall, NW; Swartz, KJ | 1 |
| Katki, AG; Rodbard, D; Schwarz, S; Zhou, GZ | 1 |
| Lehmann, J; Tsai, C; Wood, PL | 1 |
| Block, F; Osborne, NN; Pergande, G; Schwarz, M | 1 |
| Folbergrová, J | 2 |
| Pierce, RC; Rebec, GV | 1 |
| Arnelle, DR; Choi, YB; D'Emilia, DM; Kim, WK; Kumar, S; Lipton, SA; Rayudu, PV; Stamler, JS | 1 |
| Dalton, ML; Gadson, PF; Rosenquist, TH; Wrenn, RW | 1 |
| Brown, JC; Monaghan, DT; Rosenquist, TH | 1 |
| Folbergrová, J; Haugvicová, R; Mares, P | 1 |
| Jara-Prado, A; Martinez-Ruano, L; Ortega-Vazquez, A; Rios, C; Santamaria, A | 1 |
| Dhivant, S; Mitton, K; Ortiz, DO; Rogers, E; Shea, TB; Tjiattas, L | 1 |
| Breckenridge, J; Brown, AT; Chen, H; Eidt, J; Fitzgerald, R; Kazi, R; Moursi, MM; Mukunyadzi, P; Qureshi, I; Wang, Y; Wu, Y; Zhang, X | 1 |
| Caboche, J; Delabar, J; Janel, N; Ledru, A; Pagès, C; Robert, K | 1 |
| da Silva, LF; Menescal-de-Oliveira, L; Ramos Coutinho, M | 1 |
| Coutinho, MR; Menescal-de-Oliveira, L | 1 |
| Djurić, D; Hrnčić, D; Lončar-Stevanović, H; Macut, D; Rašić-Marković, A; Stanojlović, O | 1 |
| Boldyrev, AA; Bryushkova, EA; Stepanova, MS; Vladychenskaya, EA | 1 |
| Boldyrev, A; Tyulina, O; Urano, S; Vladychenskaya, E | 1 |
| Liu, J; Lu, R; Shen, J; Suo, WZ; Xiao, S; Yang, L; Zhang, B; Zhao, Z | 1 |
| Akkuratov, E; Boldyrev, A; Brodskaya, O; Dizhevskaya, A; Kulebyakin, K; Rybakova, Y | 1 |
| An, SC; Liu, H; Qiao, H; Wen, LM | 1 |
| Coutinho, MR; Ferreira, MD; Menescal-de-Oliveira, L; Zugaib, J | 1 |
| Feng, L; Han, C; Li, M; Liu, J; Mao, J; Pang, X; Wang, S; Wu, D; Zhang, X; Zhao, J | 1 |
| Barudzic, N; Djuric, DM; Jakovljevic, V; Radovanovic, A; Srejovic, I; Stanojlovic, O; Zivkovic, V | 1 |
| Kalani, A; Kamat, PK; Kyles, P; Tyagi, N | 1 |
| Flatt, PR; Guo-Parke, H; Irwin, N; McClenaghan, NH; Moffett, RC; Patterson, S; Scullion, SM | 1 |
| Takemoto, Y | 1 |
| Folbergrová, J; Haugvicová, R; Kubová, H; Mareš, P | 1 |
| Bobermin, LD; Dos Santos, TM; Quincozes-Santos, A; Siebert, C; Wyse, ATS | 1 |
| Liang, X; Liu, H; Luo, S; Sai, N; Wang, M; Wang, X; Zhang, Q; Zhang, X | 1 |
32 other study(ies) available for homocysteine and dizocilpine maleate
| Article | Year |
|---|---|
Homocysteic acid lesions in rat striatum spare somatostatin-neuropeptide Y (NADPH-diaphorase) neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Homocysteine; Immunohistochemistry; Male; Neuropeptide Y; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Somatostatin; Substance P | 1990 |
L-homocysteate stimulates [3H]MK-801 binding to the phencyclidine recognition site and is thus an agonist for the N-methyl-D-aspartate-operated cation channel.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Homocysteine; In Vitro Techniques; Ion Channels; Kinetics; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Stereoisomerism; Stimulation, Chemical | 1990 |
Homocysteic acid as a putative excitatory amino acid neurotransmitter: I. Postsynaptic characteristics at N-methyl-D-aspartate-type receptors on striatal cholinergic interneurons.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Animals; Choline; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; Homocysteine; Interneurons; Magnesium; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereoisomerism; Tachyphylaxis; Tiletamine | 1988 |
Immunohistochemical evidence for flupirtine acting as an antagonist on the N-methyl-D-aspartate and homocysteic acid-induced release of GABA in the rabbit retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminopyridines; Animals; Dizocilpine Maleate; gamma-Aminobutyric Acid; Homocysteine; Immunohistochemistry; Kainic Acid; Rabbits; Receptors, N-Methyl-D-Aspartate; Retina | 1994 |
NMDA and not non-NMDA receptor antagonists are protective against seizures induced by homocysteine in neonatal rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Animals, Newborn; Anticonvulsants; Dizocilpine Maleate; Glutamates; Homocysteine; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures | 1994 |
Intraneostriatal administration of glutamate antagonists increases behavioral activation and decreases neostriatal ascorbate via nondopaminergic mechanisms.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid; Dizocilpine Maleate; Glutamates; Glutamic Acid; Homocysteine; Infusions, Parenteral; Male; Motor Activity; Neostriatum; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1993 |
Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; Animals; Cells, Cultured; Cerebral Cortex; Child; Dizocilpine Maleate; Embryo, Mammalian; Evoked Potentials; Glycine; Homocysteine; Humans; Kinetics; Kynurenic Acid; N-Methylaspartate; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
Anticonvulsant action of both NMDA and non-NMDA receptor antagonists against seizures induced by homocysteine in immature rats.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Anticonvulsants; Behavior, Animal; Brain Chemistry; Dizocilpine Maleate; Dose-Response Relationship, Drug; Energy Metabolism; Excitatory Amino Acid Antagonists; Glutamates; Homocysteine; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 1997 |
Homocysteine signal cascade: production of phospholipids, activation of protein kinase C, and the induction of c-fos and c-myb in smooth muscle cells.
Topics: Aorta, Abdominal; Aorta, Thoracic; Cardiovascular Diseases; Cell Division; Diglycerides; Dizocilpine Maleate; DNA; Enzyme Activation; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genes, fos; Glutamic Acid; Homocysteine; Humans; Immunoblotting; Muscle, Smooth, Vascular; N-Methylaspartate; Oncogenes; Pipecolic Acids; Polymerase Chain Reaction; Precipitin Tests; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; RNA | 1997 |
ERK2 activation by homocysteine in vascular smooth muscle cells.
Topics: Abdomen; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; Homocysteine; Mitogen-Activated Protein Kinase 1; Muscle, Smooth, Vascular; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Thorax | 1998 |
Behavioral and metabolic changes in immature rats during seizures induced by homocysteic acid: the protective effect of NMDA and non-NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Energy Metabolism; Epilepsy; Excitatory Amino Acid Antagonists; Glucose; Homocysteine; Injections, Intraventricular; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 2000 |
Homocysteine-induced brain lipid peroxidation: effects of NMDA receptor blockade, antioxidant treatment, and nitric oxide synthase inhibition.
Topics: Acetylcysteine; Animals; Antioxidants; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Homocysteine; Indazoles; Lipid Peroxidation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Thiobarbituric Acid Reactive Substances | 2003 |
Folate deficiency and homocysteine induce toxicity in cultured dorsal root ganglion neurons via cytosolic calcium accumulation.
Topics: Adenine; Aniline Compounds; Animals; Calcium; Cells, Cultured; Chick Embryo; Cytosol; Dizocilpine Maleate; Folic Acid; Folic Acid Deficiency; Ganglia, Spinal; Homocysteine; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; Neurons; Nimodipine; Oxidative Stress; Reactive Oxygen Species; Thapsigargin; Xanthenes | 2004 |
Identification of a homocysteine receptor in the peripheral endothelium and its role in proliferation.
Topics: Animals; Blotting, Western; Carotid Arteries; Cell Count; Cell Division; Cells, Cultured; Dizocilpine Maleate; DNA, Complementary; Endothelium, Vascular; Excitatory Amino Acid Antagonists; Gene Expression; Homocysteine; Immunohistochemistry; In Vitro Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2005 |
Regulation of extracellular signal-regulated kinase by homocysteine in hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Blotting, Western; Chelating Agents; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Glycine; Hippocampus; Homocysteine; Immunohistochemistry; In Vitro Techniques; Male; Mice; Mice, Knockout; Signal Transduction; Tetrodotoxin; Time Factors | 2005 |
Modulation of tonic immobility in guinea pig PAG by homocysteic acid, a glutamate agonist.
Topics: Analysis of Variance; Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Guinea Pigs; Homocysteine; Immobility Response, Tonic; Male; Microinjections; Periaqueductal Gray | 2008 |
Role of homocysteic acid in the guinea pig (Cavia porcellus) anterior cingulate cortex in tonic immobility and the influence of NMDA receptors on the dorsal PAG.
Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Guinea Pigs; Gyrus Cinguli; Homocysteine; Immobility Response, Tonic; Male; Microinjections; Periaqueductal Gray; Receptors, N-Methyl-D-Aspartate | 2010 |
The effect of N-methyl-D-aspartate receptor antagonists on D,L-homocysteine thiolactone induced seizures in adult rats.
Topics: Animals; Dizocilpine Maleate; Homocysteine; Male; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 2011 |
Effect of homocysteine on properties of neutrophils activated in vivo.
Topics: Animals; Dizocilpine Maleate; Homocysteine; N-Methylaspartate; Neutrophil Activation; Neutrophils; Rats; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate | 2011 |
Rat lymphocytes express NMDA receptors that take part in regulation of cytokine production.
Topics: Animals; Benzophenanthridines; Calcium; Cell Membrane; Cytokines; Cytoplasm; Dizocilpine Maleate; Flow Cytometry; Fluorescence; Free Radicals; Homocysteine; Interferon-gamma; Lymphocytes; N-Methylaspartate; NADPH Oxidases; Nitric Oxide; Protein Kinase C; Rats; Receptors, N-Methyl-D-Aspartate; Tumor Necrosis Factor-alpha | 2011 |
Differentiation of HT22 neurons induces expression of NMDA receptor that mediates homocysteine cytotoxicity.
Topics: Animals; Cell Death; Cell Differentiation; Cell Survival; Cells, Cultured; Cytotoxins; Dizocilpine Maleate; Hippocampus; Homocysteine; Memantine; Mice; Neurons; Receptors, N-Methyl-D-Aspartate | 2012 |
Receptor-mediated oxidative stress in murine cerebellar neurons is accompanied by phosphorylation of MAP (ERK 1/2) kinase.
Topics: Animals; Antioxidants; Carnosine; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Homocysteine; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; N-Methylaspartate; Neurons; Ouabain; Oxidative Stress; Phosphorylation; Primary Cell Culture; Rats; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium-Potassium-Exchanging ATPase | 2012 |
[Modulation of hippocampal glutamate and NMDA/AMPA receptor by homocysteine in chronic unpredictable mild stress-induced rat depression].
Topics: Animals; Behavior, Animal; Depression; Dizocilpine Maleate; Glutamic Acid; Hippocampus; Homocysteine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Stress, Psychological | 2013 |
Glutamate/GABA balance in ACC modulates the nociceptive responses of vocalization: an expression of affective-motivational component of pain in guinea pigs.
Topics: Animals; Bicuculline; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; GABA Agents; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Gyrus Cinguli; Homocysteine; Male; Microinjections; Muscimol; Pain; Time Factors; Vocalization, Animal | 2014 |
Homocysteine induces the expression of C-reactive protein via NMDAr-ROS-MAPK-NF-κB signal pathway in rat vascular smooth muscle cells.
Topics: Animals; Atherosclerosis; C-Reactive Protein; Cells, Cultured; Dizocilpine Maleate; Gene Expression Regulation; Homocysteine; Hyperhomocysteinemia; Interleukins; Male; MAP Kinase Signaling System; Methionine; Mitogen-Activated Protein Kinases; Myocytes, Smooth Muscle; NF-kappa B; Onium Compounds; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Signal Transduction; Superoxides; Thenoyltrifluoroacetone | 2014 |
The effects of the modulation of NMDA receptors by homocysteine thiolactone and dizocilpine on cardiodynamics and oxidative stress in isolated rat heart.
Topics: Animals; Biomarkers; Coronary Circulation; Dizocilpine Maleate; Heart; Heart Function Tests; Homocysteine; In Vitro Techniques; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2015 |
Hydrogen Sulfide Ameliorates Homocysteine-Induced Alzheimer's Disease-Like Pathology, Blood-Brain Barrier Disruption, and Synaptic Disorder.
Topics: Alzheimer Disease; Animals; Antigens, CD; Avoidance Learning; Blood-Brain Barrier; Cadherins; Cerebrovascular Circulation; Claudin-5; Cystathionine beta-Synthase; Dizocilpine Maleate; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Homocysteine; Hydrogen Sulfide; Intercellular Adhesion Molecule-1; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Memory; Mice, Inbred C57BL; Microtubule-Associated Proteins; Microvessels; Nerve Tissue Proteins; Permeability; RNA, Messenger; Synapses | 2016 |
Evaluation of the role of N-methyl-D-aspartate (NMDA) receptors in insulin secreting beta-cells.
Topics: Animals; Calcium; Cell Line; Dizocilpine Maleate; DNA Damage; Excitatory Amino Acid Antagonists; Gene Expression; Homocysteine; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Membrane Potentials; Rats; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2016 |
Central cardiovascular actions of L-homocysteine microinjected into ventrolateral medullary autonomic areas of the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blood Pressure; Dizocilpine Maleate; Heart Rate; Homocysteine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Ventral Thalamic Nuclei | 2016 |
Do stereoisomers of homocysteic acid exhibit different convulsant action in immature rats?
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzodiazepines; Dizocilpine Maleate; Homocysteine; Male; Quinoxalines; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Stereoisomerism | 2019 |
Mild Hyperhomocysteinemia Causes Anxiety-like Behavior and Brain Hyperactivity in Rodents: Are ATPase and Excitotoxicity by NMDA Receptor Overstimulation Involved in this Effect?
Topics: Animals; Anxiety; Brain; Dizocilpine Maleate; Glutamate-Ammonia Ligase; Glutamic Acid; Homocysteine; Hyperhomocysteinemia; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Rodentia; Sodium-Potassium-Exchanging ATPase; Sucrose | 2022 |
Homocysteine can aggravate depressive like behaviors in a middle cerebral artery occlusion/reperfusion rat model: a possible role for NMDARs-mediated synaptic alterations.
Topics: Animals; Dizocilpine Maleate; Homocysteine; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reperfusion; Stroke | 2023 |