homocysteine has been researched along with cystathionine in 143 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 49 (34.27) | 18.7374 |
| 1990's | 15 (10.49) | 18.2507 |
| 2000's | 49 (34.27) | 29.6817 |
| 2010's | 24 (16.78) | 24.3611 |
| 2020's | 6 (4.20) | 2.80 |
| Authors | Studies |
|---|---|
| Dow, MJ; Kokkeler, SC; Miller, LT | 1 |
| Halaseh, A; McConnell, WB; Nigam, SN | 1 |
| Beaton, JM | 1 |
| Grabski, J; Paszewski, A | 2 |
| Hamilton, H; Iles, JF | 1 |
| Miller, JW; Selhub, J | 1 |
| Harvey, PR; Ilson, RG; Strasberg, SM | 1 |
| Allard, D; Ceballos, I; Chadefaux, B; Jérôme, H | 1 |
| Finkelstein, JD; Harris, BJ; Martin, JJ | 1 |
| Duerre, JA; Wallwork, JC | 1 |
| Brodie, AE; Reed, DJ | 1 |
| Chatagner, F; de Billy, G; Ipaktchi, M; Lefauconnier, JM; Portemer, C | 1 |
| Flavin, M; Savin, MA | 1 |
| Beaton, JM; Bradley, RJ; Bridgers, WF; McClain, LD; Pegram, GV; Smythies, JR | 1 |
| Jacoby, LB; Littlefield, JW | 1 |
| Finkelstein, JD; Harris, BJ; Kyle, WE | 1 |
| Cello, JP; Finkelstein, JD; Kyle, WE | 1 |
| Bourel, M; Le Guilly, Y; Lenoir, P; Simon, M | 1 |
| Corwin, LM; Rothman, SW | 1 |
| Paszewski, A; Pieniazek, N; Stepień, PP | 1 |
| Collins, JM; Monty, KJ | 1 |
| Greene, RC; Kung, HF; Spears, C; Weissbach, H; Williams, RD | 1 |
| Finkelstein, JD | 2 |
| Hakami, N; Sagerson, RN; Scott, CR; Teng, CC | 1 |
| Coignet, J; Laurent, B | 1 |
| Boucher, Y; Lachance, RA; Paquin, R | 1 |
| Barboza, V; Fernandez, E; Pulgar, J | 1 |
| Jung, G; Ottnad, M; Rimpler, M | 1 |
| Florentiev, VL; Goryachenkova, EV; Polyakova, LA; Yefremova, LL | 1 |
| Gaull, G; Schaffner, F; Sturman, JA | 1 |
| Gaull, GE; Pascal, TA; Sturman, JA; Tallan, HH | 1 |
| Hirayama, K; Ikegami, T; Kodama, H; Mizuhara, S | 1 |
| Hodgson, E; Rock, GC; Sharma, GK | 1 |
| Chatagner, F; Deme, D | 1 |
| McCully, KS | 1 |
| Ngo, TT; Shargool, PD | 1 |
| Keiser, HR; Lovenberg, W; Sjoerdsma, A; Slavik, M | 1 |
| Carson, DA; Kamatani, N | 1 |
| Cavanagh, JB; Kemplay, S | 1 |
| Hong, JS; Simon, M | 1 |
| Dwivedi, CM; Ragin, RC; Uren, JR | 1 |
| Morzycka, E; Paszewski, A | 1 |
| Kimoto, M; Ogawa, T; Sasaoka, K | 1 |
| Beatty, PW; Reed, DJ | 1 |
| Alonso-Aperte, E; Alvarez, L; Caballería, J; Deulofeu, R; Gassó, M; Mato, JM; Rodés, J; Rubio, M; Varela-Moreiras, G | 1 |
| Allen, RH; Joosten, E; Lindenbaum, J; Naurath, HJ; Riezler, R; Stabler, SP | 1 |
| Glueck, CJ; Lang, JE; Shaw, P; Sieve-Smith, L; Tracy, T; Wang, Y | 1 |
| Douce, R; Droux, M; Ravanel, S | 2 |
| Bukovska, G; Kery, V; Kraus, JP | 1 |
| Kodama, H; Kurashige, T; Okada, T; Sugahara, K; Takechi, T; Wakiguchi, H | 1 |
| González-Fernández, M; Rey de Viñas, JL; Sandoval, MC | 1 |
| Allen, RH; Delport, R; Riezler, R; Stabler, SP; Ubbink, JB; van der Merwe, A; Vermaak, WJ | 1 |
| Allen, RH; Buccellato, FR; Lindenbaum, J; Lorenzini, EC; Morabito, A; Scalabrino, G; Tredici, G | 1 |
| Abrahamsson, L; Andersson, M; Bagby, J; Dyrehag, LE; Gottfries, CG; Regland, B | 1 |
| Chambers, D; Dargusch, R; Davis, J; Maher, P; Sagara, Y; Schubert, D | 1 |
| Allen, RH; Cohen, JA; Estacio, R; Jeffers, BW; Schrier, RW; Stabler, SP | 1 |
| Graefe, U; Henning, BF; Langer, K; Raidt, H; Riezler, R; Tepel, M; Zidek, W | 1 |
| Berthold, HK; Brensing, KA; Look, MP; Reichel, C; Riezler, R; Rockstroh, JK; Sauerbruch, T; Spengler, U; Stabler, SP | 1 |
| Banerjee, R; Cranford, MR; Mosharov, E | 1 |
| Bodis, M; Geisel, J; Herrmann, W; Knapp, JP; Müller, A; Schorr, H; Stein, G | 1 |
| Goto, K; Ichioka, K; Iwama, T; Mizuno, Y; Yamagata, S | 1 |
| Følling, I; Guttormsen, AB; Kim, CE; Kruger, WD; Ose, L; Refsum, H; Ueland, PM | 1 |
| Fukagawa, NK; MacCoss, MJ; Matthews, DE | 1 |
| Chango, A; James, SJ; Melnyk, S; Pogribna, M; Pogribny, I; Yi, P | 1 |
| Chambers, JC; Doré, CJ; Kooner, JS; Refsum, H; Ueland, PM; Wright, M | 1 |
| Gromeier, S; Herrmann, W; Julius, U; Pietzsch, J; Schorr, H | 1 |
| Onodera, R; Or-Rashid, MM; Wadud, S | 1 |
| Dunn, MF; Jhee, KH; McPhie, P; Miles, EW; Niks, D | 2 |
| Bodis, M; Geisel, J; Herrmann, W; Hübner, U; Knapp, JP; Schorr, H; Zimbelmann, I | 1 |
| Geisel, J; Herrmann, W; Riegel, W; Schorr, H | 1 |
| Naurath, HJ; Pütter, S; Riezler, R; Ubbink, JB | 1 |
| Allen, RH; Berthold, HK; Look, MP; Riezler, R; Rockstroh, JK; Sauerbruch, T; Schliefer, K; Stabler, SP | 1 |
| Ruaux, CG; Steiner, JM; Williams, DA | 1 |
| Banerjee, R; Taoka, S | 1 |
| Allen, RH; Kraus, JP; Mudd, SH; Oliveriusova, J; Stabler, SP; Steegborn, C; Wagner, C; Wahl, MC | 1 |
| Kanemoto, N; Kinda, T; Nakagawa, K; Shiraiwa, T; Yamamoto, H | 1 |
| Hamer, JE; Hamer, L; Lo, SC | 1 |
| Aitken, SM; Kirsch, JF | 2 |
| Busch, M; Franke, S; Kientsch-Engel, R; Müller, A; Sommer, M; Stein, G | 1 |
| Ishikawa, K; Mino, K | 1 |
| EGER, W | 1 |
| HAROLD, FM | 1 |
| FLAVIN, M; SLAUGHTER, C | 1 |
| ROWBURY, RJ; WOODS, DD | 1 |
| Nijhout, HF; Reed, MC; Sparks, R; Ulrich, CM | 1 |
| White, RH | 1 |
| Guttormsen, AB; Refsum, H; Solheim, E | 1 |
| Nakano, E; Powers, HJ; Williams, NH; Williamson, MP | 1 |
| Busch, M; Franke, C; Franke, S; Klemm, A; Lang, D; Müller, A; Passlick-Deetjen, J; Stein, G | 1 |
| Abrahamsson, L; Blennow, K; Gottfries, CG; Grenfeldt, B; Regland, B | 1 |
| Bleie, Ø; Guttormsen, AB; Nexo, E; Nordrehaug, JE; Nygård, O; Refsum, H; Schneede, J; Ueland, PM; Vollset, SE | 1 |
| Herrmann, W; Köhler, H; Kuhlmann, MK; Obeid, R | 1 |
| Geisel, J; Herrmann, W; Hübner, U; Koch, I; Obeid, R; Retzke, U | 1 |
| Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA | 1 |
| Herrmann, W; Kirsch, CM; Kuhlmann, M; Obeid, R | 1 |
| Allen, R; Boger, R; Doshi, S; Goodfellow, J; Lewis, M; McDowell, I; Moat, S; Newcombe, R; Stabler, S | 1 |
| Fowler, B; Herrmann, W; Kuhlmann, MK; Makowski, J; Obeid, R; Schorr, H | 1 |
| Bar-Or, D; Kraus, JP; Rael, LT; Thomas, GW | 1 |
| Fotakis, G; Timbrell, JA | 1 |
| Campbell, CD; Ficicioglu, C; Ganesh, J | 1 |
| Amao, M; Kawamata, Y; Kimura, T; Kodama, R; Sakai, R; Toue, S | 1 |
| Garlick, PJ | 1 |
| Geier, DA; Geier, MR | 1 |
| Chan, L; Durante, W; Gaubatz, J; Hui, R; Jiang, X; Li, Z; Liao, D; Pownall, HJ; Schafer, AI; Tan, H; Wang, H; Yang, F; Yang, X | 1 |
| Auger, S; Barzu, O; Danchin, A; Hullo, MF; Martin-Verstraete, I; Soutourina, O; Yvon, M | 1 |
| Becker, G; Fassbender, K; Herrmann, W; Kasoha, M; Knapp, JP; Kostopoulos, P; Obeid, R | 1 |
| Baggott, JE; Tamura, T | 2 |
| STEKOL, JA | 1 |
| Atherton, JC; Barrett, DA; Doherty, NC; Halliday, NM; Hardie, KR; Shen, F; Winzer, K | 1 |
| Aitken, SM; Hopwood, EM; Lodha, PH; Manders, AL | 1 |
| Albanese, A; Bowlus, CL; Devaraj, S; French, SW; Gregory, JF; Halsted, CH; Medici, V; Panacek, EA; Peerson, JM; Rahim, N; Richards, JR; Rossaro, L; Stabler, SP; Virata, MC | 1 |
| Ballou, DP; Banerjee, R; Singh, S | 1 |
| Goossens, L | 1 |
| Ericson, K; Gibson, CR; Heer, M; Mader, TH; Ploutz-Snyder, R; Smith, SM; Zwart, SR | 1 |
| Boyd, RN; Davies, PS; Moxon-Lester, L; Obeid, R; Schoendorfer, NC; Sharp, N; Vitetta, L | 1 |
| Cecere, N; de Paola, I; DellaGreca, M; Longobardo, L | 1 |
| Dekker, JM; Drevon, CA; Elshorbagy, AK; Nijpels, G; Nurk, E; Nygård, O; Refsum, H; Stehouwer, CD; Teerlink, T; Tell, GS; Ueland, PM; Vinknes, KJ; Vollset, SE | 1 |
| Bártl, J; Chrastina, P; Hodík, J; Kožich, V; Krijt, J; Pešková, K | 1 |
| Aliani, M; House, JD; Mayengbam, S; Raposo, S | 1 |
| Hirschberger, LL; Jurkowska, H; Roman, HB; Stipanuk, MH | 1 |
| Chi, YY; Coats, B; Gregory, JF; Midttun, Ø; Ralat, M; Rios-Avila, L; Stacpoole, PW; Ueland, PM | 1 |
| Björkqvist, HG; Carlsson, GU; Gustavsson, BG; Kurlberg, GK; Odin, EA; Stoffregen, CC; Tångefjord, MT | 1 |
| Faas, MM; Holwerda, KM; Lely, AT; Nolte, IM; Staff, AC; van Goor, H; Weedon-Fekjær, MS | 1 |
| Balan, B; Beri, D; Chaubey, S; Subramaniam, S; Surendra, B; Tatu, U | 1 |
| Makino, R; Okuyama, H; Tachibana, T; Tomonaga, S | 1 |
| Huse, K; Olecka, M; Platzer, M | 1 |
| Abdul Rehman, SA; Ali, MF; Devi, S; Gourinath, S; Tarique, KF | 1 |
| Han, C; Liu, S; Liu, Y; Shi, L; Xiang, X | 1 |
| Belardo, A; Gevi, F; Zolla, L | 1 |
| Bakolitsa, C; Brenner, SE; Bromberg, Y; Cao, C; Capriotti, E; Casadio, R; De Baets, G; Dimster-Denk, DF; Friedberg, I; Giollo, M; Hu, Z; Karchin, R; Kasak, L; Katsonis, P; Leonardi, E; Lichtarge, O; Martelli, PL; Masica, D; Mooney, SD; Moult, J; Olatubosun, A; Pal, LR; Pandey, G; Radivojac, P; Repo, S; Rine, J; Rousseau, F; Savojardo, C; Schymkowitz, J; Thusberg, J; Tosatto, SCE; Väliaho, J; Van Durme, J; Vihinen, M; Yu, C | 1 |
| Corrales, F; Franco, L; Guerrero, L; López-Rodas, G; Martí-Andrés, P; Paradela, A; Pérez, S; Rius-Pérez, S; Sastre, J; Taléns-Visconti, R; Torres, L; Torres-Cuevas, I | 1 |
| Bai, L; Du, J; Huang, Y; Jin, H; Kong, W; Tang, C; Wang, X; Wang, Y; Zhang, D; Zhang, L | 1 |
| Astegno, A; Conter, C; Dominici, P; Fernández-Rodríguez, C; Fruncillo, S; Martínez-Cruz, LA | 1 |
| Danshiitsoodol, N; Ezumi, Y; Izuhara-Kihara, H; Kumagai, T; Matoba, Y; Noda, M; Oda, K; Sugiyama, M; Yasutake, C; Yoshida, T | 1 |
| Chen, P; He, Q; Jiang, J; Liu, L; Shi, H; Song, Y; Tang, Y; Wang, B; Zhang, N; Zhou, H; Zhou, Z | 1 |
| Bastani, NE; Dagnelie, PC; Elshorbagy, AK; Eussen, SJPM; Grootswagers, P; Kožich, V; Olsen, T; Refsum, H; Retterstøl, K; Stehouwer, CD; Stolt, ETK; Tore, EC; van Greevenbroek, MMJ; Vinknes, KJ | 1 |
| Aghalarov, M; Aktuglu-Zeybek, C; Cansever, MS; Kıykım, E; Uygur, E; Zubarioglu, T | 1 |
7 review(s) available for homocysteine and cystathionine
| Article | Year |
|---|---|
Methylation & schizophrenia.
Topics: Amines; Amino Acids; Animals; Behavior, Animal; Catecholamines; Cats; Cystathionine; Cysteine; Dihydroxyphenylalanine; Drug Tolerance; Hallucinogens; Homocysteine; Humans; Indoles; Methionine; Methylation; Mice; Schizophrenia; Serine; Taurine | 1975 |
The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine.
Topics: Amino Acid Metabolism, Inborn Errors; Cystathionine; Homocysteine; Humans; Methionine; Methylation; S-Adenosylmethionine | 1992 |
Methionine metabolism in mammals: the biochemical basis for homocystinuria.
Topics: Alcohol Oxidoreductases; Cell-Free System; Cystathionine; Fibroblasts; Homocysteine; Homocystinuria; Humans; Hydro-Lyases; Liver; Methionine; Methylation; Methyltransferases; Protein Biosynthesis; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates | 1974 |
Pathways and regulation of homocysteine metabolism in mammals.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Heme; Homocysteine; Isoenzymes; Kinetics; Mammals; Methionine; Methionine Adenosyltransferase; Organ Specificity; Oxidation-Reduction; Pyridoxal Phosphate; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tetrahydrofolates | 2000 |
The enzymology of cystathionine biosynthesis: strategies for the control of substrate and reaction specificity.
Topics: Allosteric Regulation; Amino Acid Substitution; Binding Sites; Carbon-Oxygen Lyases; Catalysis; Catalytic Domain; Cystathionine; Cystathionine beta-Synthase; Dimerization; Enzyme Activation; Gene Expression Regulation, Enzymologic; Homocysteine; Kinetics; Oxidation-Reduction; Protein Structure, Tertiary; Pyridoxal Phosphate; Stereoisomerism; Substrate Specificity | 2005 |
Toxicity of methionine in humans.
Topics: Cystathionine; Diet; Endothelium, Vascular; Homocysteine; Humans; Infant; Infant Nutritional Physiological Phenomena; Methionine; Nutritional Physiological Phenomena; Nutritional Requirements | 2006 |
Homocysteine, iron and cardiovascular disease: a hypothesis.
Topics: Biomarkers; Cardiovascular Diseases; Cystathionine; Dietary Supplements; Folic Acid; Free Radicals; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Lipoproteins, LDL; Methionine; Risk Factors; S-Adenosylhomocysteine; Vitamin B Complex | 2015 |
14 trial(s) available for homocysteine and cystathionine
| Article | Year |
|---|---|
Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations.
Topics: Aged; Aged, 80 and over; Avitaminosis; Citrates; Cystathionine; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Injections, Intramuscular; Male; Methylmalonic Acid; Placebos; Prospective Studies; Pyridoxine; Vitamin B 12; Vitamin B 12 Deficiency | 1995 |
Total homocysteine is associated with nephropathy in non-insulin-dependent diabetes mellitus.
Topics: Adult; Aged; Albuminuria; Cystathionine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Kidney Function Tests; Male; Methylmalonic Acid; Middle Aged; Regression Analysis; Vitamins | 1999 |
Is the increase in serum cystathionine levels in patients with liver cirrhosis a consequence of impaired homocysteine transsulfuration at the level of gamma-cystathionase?
Topics: Adolescent; Adult; Aged; Analysis of Variance; Biomarkers; Chromatography, Gas; Cystathionine; Cystathionine gamma-Lyase; Female; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Liver Cirrhosis; Male; Middle Aged; Probability; Reference Values; Sensitivity and Specificity; Severity of Illness Index; Statistics, Nonparametric | 2000 |
Measurement of intracellular sulfur amino acid metabolism in humans.
Topics: Adult; Carbon Isotopes; Cystathionine; Energy Metabolism; Female; Homocysteine; Humans; Male; Methionine; Tritium | 2001 |
Investigation of relationship between reduced, oxidized, and protein-bound homocysteine and vascular endothelial function in healthy human subjects.
Topics: Administration, Oral; Adult; Brachial Artery; Cystathionine; Cysteine; Endothelium, Vascular; Female; Homocysteine; Humans; Male; Methionine; Oxidation-Reduction; Proteins; Time Factors; Vasodilation | 2001 |
Homocysteine levels in patients treated with lipid apheresis: effect of a vitamin therapy.
Topics: Adult; Cystathionine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipoproteinemia Type II; Lipids; Male; Vitamin B 12; Vitamin B 6 | 2001 |
Decrease of elevated N,N-dimethylglycine and N-methylglycine in human immunodeficiency virus infection during short-term highly active antiretroviral therapy.
Topics: Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Antigens, CD; Antiretroviral Therapy, Highly Active; Biomarkers; Cystathionine; Cysteine; Fasting; Female; Folic Acid; HIV Infections; HIV-1; Homocysteine; Humans; Male; Methionine; Methylmalonic Acid; Middle Aged; Multivariate Analysis; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Sarcosine; Vitamin B 6 | 2001 |
Variation in plasma cystathionine and its relation to changes in plasma concentrations of homocysteine and methionine in healthy subjects during a 24-h observation period.
Topics: Adult; Circadian Rhythm; Cystathionine; Fasting; Female; Food; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Methionine | 2004 |
Influence of hemodialysis membrane permeability on serum levels of advanced glycation end products (AGEs) and homocysteine metabolites.
Topics: Arginine; Cross-Over Studies; Cystathionine; Enzyme-Linked Immunosorbent Assay; Female; Fluorescence; Glycation End Products, Advanced; Homocysteine; Humans; Kidneys, Artificial; Lysine; Male; Membranes, Artificial; Middle Aged; Polymers; Prospective Studies; Renal Dialysis; Sarcosine; Sulfones | 2004 |
Changes in basal and postmethionine load concentrations of total homocysteine and cystathionine after B vitamin intervention.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analysis of Variance; Cardiovascular Diseases; Cystathionine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Norway; Prospective Studies; Vitamin B 12; Vitamin B 6 | 2004 |
Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia.
Topics: Acetylcysteine; Adult; Arginine; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Cystathionine; Cysteine; Dipeptides; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Male; Methionine; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vasodilation | 2005 |
Iron-dependent formation of homocysteine from methionine and other thioethers.
Topics: Adult; Area Under Curve; Cross-Over Studies; Cystathionine; Female; Homocysteine; Humans; Hydrogen-Ion Concentration; Iron; Iron Chelating Agents; Male; Methionine; S-Adenosylhomocysteine | 2007 |
Simultaneous determination of cystathionine, total homocysteine, and methionine in dried blood spots by liquid chromatography/tandem mass spectrometry and its utility for the management of patients with homocystinuria.
Topics: Adolescent; Child; Child, Preschool; Chromatography, Liquid; Cystathionine; Disease Management; Dried Blood Spot Testing; Female; Homocysteine; Homocystinuria; Humans; Infant; Infant, Newborn; Male; Methionine; Tandem Mass Spectrometry | 2014 |
Reduced folate and serum vitamin metabolites in patients with rectal carcinoma: an open-label feasibility study of pemetrexed with folic acid and vitamin B12 supplementation.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cystathionine; Feasibility Studies; Female; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Intestinal Mucosa; Male; Methylmalonic Acid; Middle Aged; Neoadjuvant Therapy; Pemetrexed; Rectal Neoplasms; Rectum; Vitamin B 12 | 2016 |
122 other study(ies) available for homocysteine and cystathionine
| Article | Year |
|---|---|
Methionine metabolism and vitamin B6 status in women using oral contraceptives.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Contraceptives, Oral; Contraceptives, Oral, Combined; Cystathionine; Female; Homocysteine; Humans; Methionine; Pyridoxine; Taurine | 1978 |
Biosynthesis and metabolism of cystathionine in Astragalus pectinatus.
Topics: Cystathionine; Cysteine; Homocysteine; Methionine; Plants; Sulfur | 1977 |
Enzymatic lesions in methionine mutants of Aspergillus nidulans: role and regulation of an alternative pathway for cysteine and methionine synthesis.
Topics: Aspergillus nidulans; Cystathionine; Cysteine; Genes, Regulator; Glutathione; Homocysteine; Lyases; Methionine; Mutation; Suppression, Genetic; Taurine | 1975 |
Effects of glutamate and sulphur containing amino acids on ammonia toxicity and methionine sulphoximine convulsions in mice.
Topics: Amino Acids, Sulfur; Animals; Anticonvulsants; Arginine; Cystathionine; Cysteic Acid; Glutamates; Homocysteine; Male; Methionine; Methionine Sulfoximine; Mice; Quaternary Ammonium Compounds; Seizures; Taurine | 1976 |
The simultaneous determination of oxidized and reduced glutathiones in liver tissue by ion pairing reverse phase high performance liquid chromatography with a coulometric electrochemical detector.
Topics: Animals; Bile; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Electrochemistry; Glutathione; Homocysteine; Liver; Male; Methionine; Oxidation-Reduction; Rats | 1989 |
[Effects of gene localization and its metabolic significance in trisomy 21].
Topics: Chromosome Mapping; Chromosomes, Human, 21-22 and Y; Cystathionine; Cystathionine beta-Synthase; Down Syndrome; Fibroblasts; Homocysteine; Homocystinuria; Humans; Methionine | 1985 |
Methionine metabolism in mammals. The methionine-sparing effect of cystine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine; Cystathionine beta-Synthase; Cystine; Diet; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1988 |
Methionine metabolism in isolated perfused livers from rats fed on zinc-deficient and restricted diets.
Topics: Animals; Butyrates; Cystathionine; Diet; Homocysteine; In Vitro Techniques; Liver; Male; Methionine; Perfusion; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Zinc | 1986 |
Glutathione changes occurring after S-adenosylhomocysteine hydrolase inhibition.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Antigens, Neoplasm; Cells, Cultured; Cystathionine; Glutathione; Homocysteine; Hydrolases; Leukemia L5178; Liver; Male; Methionine; Oxidation-Reduction; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Redistribution of pyridoxal phosphate in the male rat liver as a result of repeated injections of hydrocortisone.
Topics: Alanine Transaminase; Animals; Aspartic Acid; Carboxy-Lyases; Cystathionine; Cysteine; Dose-Response Relationship, Drug; Homocysteine; Homoserine; Hydro-Lyases; Hydrocortisone; L-Serine Dehydratase; Liver; Lyases; Male; Pyridoxal Phosphate; Rats; Seasons; Serine; Time Factors; Tyrosine Transaminase | 1973 |
Cystationine synthesis in yeast: an alternative pathway for homocysteine biosynthesis.
Topics: Acetates; Catalysis; Cell-Free System; Cystathionine; Cysteine; Homocysteine; Homoserine; Hydro-Lyases; L-Serine Dehydratase; Lyases; Neurospora crassa; Saccharomyces; Saccharomyces cerevisiae; Salmonella typhimurium; Sulfides; Sulfur Isotopes; Yeasts | 1972 |
A study of the behavioral disruption of mice induced by l-methionine and related compounds.
Topics: Amphetamine; Animals; Behavior, Animal; Betaine; Chlorpromazine; Cystathionine; Folic Acid; Histidine; Homocysteine; Homoserine; Male; Mescaline; Methionine; Mice; N,N-Dimethyltryptamine; Niacinamide; Serine; Social Behavior | 1974 |
Mutant human fibroblast clones able to grow on homocysteine instead of cyst(e)ine.
Topics: Alkanesulfonates; Cell Line; Clone Cells; Colorimetry; Culture Media; Cystathionine; Cystine; Diploidy; Fibroblasts; Homocysteine; Humans; Karyotyping; Lyases; Mutagens; Mutation; Nitrosoguanidines; Skin; Stereoisomerism | 1971 |
Methionine metabolism in mammals: regulatory effects of S-adenosylhomocysteine.
Topics: Adenosine; Animals; Betaine; Chromatography, Gel; Cystathionine; Enzyme Activation; Homocysteine; Kinetics; Liver; Lyases; Methionine; Methyltransferases; Rats; Regression Analysis | 1974 |
Ethanol-induced changes in methionine metabolism in rat liver.
Topics: Animals; Cystathionine; Dietary Proteins; Ethanol; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; S-Adenosylmethionine | 1974 |
[Influence of cysteine or of its sulfur-containing precursors on the development of adult human liver diploid cell lines and of heteroploid lines derived from the transformation of the latter].
Topics: Aneuploidy; Cell Division; Cell Line; Cells, Cultured; Culture Media; Cystathionine; Cysteine; Diploidy; Homocysteine; Humans; Liver; Methionine; Transformation, Genetic | 1972 |
Factors affecting virulence of Shigella flexneri: defective methionine synthesis in an Escherichia coli-Shigella hybrid.
Topics: Animals; Cell Survival; Cystathionine; Cysteine; Escherichia coli; Genes; Genetics, Microbial; Guinea Pigs; Homocysteine; Homoserine; Hybridization, Genetic; Methionine; RNA, Bacterial; Shigella; Shigella flexneri; Species Specificity; Temperature; Transduction, Genetic; Virulence | 1972 |
An Aspergillus nidulans mutant lacking cystathionine -synthase: identity of L-serine sulfhydrylase with cystathionine -synthase and its distinctness from O-acetyl-L-serine sulfhydrylase.
Topics: Aspergillus; Aspergillus nidulans; Carbon Isotopes; Cell-Free System; Culture Media; Cystathionine; Cysteine; Homocysteine; Hydro-Lyases; Molecular Weight; Mutation; Selenium; Serine; Species Specificity | 1973 |
Studies on beta-cystathionase and omicron-acetylhomoserine sulfhydrylase as the enzymes of alternative methionine biosynthetic pathways in Aspergillus nidulans.
Topics: Acetylation; Aspergillus; Aspergillus nidulans; Cystathionine; Enzyme Repression; Homocysteine; Homoserine; Hydrogen Sulfide; Lyases; Methionine; Serine | 1973 |
The cysteine desulfhydrase of Salmonella typhimurium. Kinetic and catalytic properties.
Topics: Binding Sites; Cell-Free System; Centrifugation, Density Gradient; Chromatography, Gel; Cystathionine; Cysteine; Drug Stability; Enzyme Activation; Enzyme Induction; Homocysteine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Lyases; Mathematics; Mercaptoethanol; Methionine; Mutation; Salmonella typhimurium; Serine; Stereoisomerism; Structure-Activity Relationship; Sulfhydryl Compounds | 1973 |
Effect of methionine and vitamin B-12 on the activities of methionine biosynthetic enzymes in metJ mutants of Escherichia coli K12.
Topics: Adenosine Triphosphate; Culture Media; Cystathionine; Enzyme Repression; Escherichia coli; Folic Acid; Homocysteine; Hydro-Lyases; L-Serine Dehydratase; Methionine; Methyltransferases; Mutation; Oxidoreductases; S-Adenosylmethionine; Time Factors; Transferases; Vitamin B 12 | 1973 |
Hereditary transcobalamin II deficiency: the role of transcobalamin II in vitamin B 12 -mediated reactions.
Topics: Amino Acid Metabolism, Inborn Errors; Cystathionine; DNA; Hematopoietic System; Homocysteine; Humans; Infant; Infant, Newborn; Isomerases; Leukocytes; Malonates; Methionine; Methyltransferases; Oxidation-Reduction; Propionates; Succinates; Vitamin B 12; Vitamin B 12 Deficiency | 1972 |
[Cystathionuria and defective enzyme regulation].
Topics: Administration, Oral; Amino Acid Metabolism, Inborn Errors; Child; Chromatography, Ion Exchange; Chromatography, Paper; Cystathionine; Cysteine; Electrophoresis, Paper; Female; Homocysteine; Homocystine; Homoserine; Humans; Hydro-Lyases; Hydrocortisone; Liver; Lyases; Methionine; Pyridoxine; Sulfur | 1973 |
[Role of sulfated amino acids in the growth of Corynebacterium sepedonicum (Spieck, et Kott) Skapt. et Burkh].
Topics: Amino Acids; Chromatography, Paper; Colorimetry; Corynebacterium; Culture Media; Cystathionine; Glutathione; Homocysteine; Homocystine; Methionine; S-Adenosylmethionine; Stereoisomerism; Sulfur | 1973 |
Kinetic characteristics of cisteine desulphydrase in the liver and pancreas of different biological species.
Topics: Animals; Chickens; Cystathionine; Cysteine; Dogs; Fishes; Homocysteine; In Vitro Techniques; Kinetics; Liver; Lyases; Mice; Pancreas; Pyridoxal Phosphate; Pyruvates; Rats; Species Specificity; Swine | 1973 |
[Chiro-optical properties of sulfur containing amino acids].
Topics: Alanine; Amino Acids; Circular Dichroism; Cystathionine; Cysteine; Cystine; Homocysteine; Homocystine; Hydrogen-Ion Concentration; Methionine; Molecular Conformation; Optical Rotatory Dispersion; Spectrophotometry, Ultraviolet; Sulfides; Sulfur; Temperature | 1973 |
Interaction of pyridoxal phosphate analogues with apoenzymes of gamma-cystathionase and serine sulphhydrase.
Topics: Animals; Apoproteins; Binding Sites; Borohydrides; Chickens; Circular Dichroism; Cystathionine; Homocysteine; Hydro-Lyases; Hydrogen Sulfide; Kinetics; Liver; Lyases; Methylation; Penicillamine; Protein Binding; Pyridoxal Phosphate; Rats; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1973 |
Homocystinuria due to cystathionine synthase deficiency: enzymatic and ultrastructural studies.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Biopsy, Needle; Child; Child, Preschool; Cystathionine; Female; Heterozygote; Homocysteine; Homocystinuria; Humans; Hydro-Lyases; Liver; Male; Methionine; Mitochondria, Liver; Pyridoxine; Transferases; Transketolase | 1974 |
Cystathionine gamma-synthesis from homocysteine and cysteine by mammalian tissue.
Topics: Animals; Brain; Chromatography, Ion Exchange; Cystathionine; Cysteine; Cystine; Homocysteine; Humans; Kidney; Liver; Lyases; Male; Mice; Organ Specificity; Precipitin Tests; Rabbits; Rats; Species Specificity; Subcellular Fractions; Sulfur Radioisotopes | 1974 |
Effect of pyridoxine treatment of a cystathioninuric patient on the urinary excretion of some unusual sulfur-containing amino acids.
Topics: Acetamides; Amino Acid Metabolism, Inborn Errors; Amino Acids, Sulfur; Autoanalysis; Chromatography, Ion Exchange; Cystathionine; Cysteine; Electrophoresis, Paper; Female; Homocysteine; Homocystine; Humans; Pyridoxine; Time Factors | 1974 |
Nutrition and metabolism of sulphur amino acids in Argyrotaenia velutinana larvae.
Topics: Animals; Cystathionine; Cysteine; Female; Germ-Free Life; Homocysteine; Insecta; Larva; Male; Metamorphosis, Biological; Methionine; Pupa | 1972 |
[Active center of rat liver homoserine dehydratase].
Topics: Alanine; Animals; Binding Sites; Cystathionine; Cysteine; Deamination; Homocysteine; Homoserine; Hydro-Lyases; Hydrogen Sulfide; Kinetics; Liver; Methionine; Protein Binding; Rats; Stereoisomerism; Structure-Activity Relationship; Sulfhydryl Compounds | 1972 |
Homocysteinemia and arteriosclerosis.
Topics: Amino Acid Metabolism, Inborn Errors; Arteriosclerosis; Cystathionine; Homocysteine | 1972 |
The formation of sulphur-containing amino acids in germinating seeds of rape (Brassica napus L.).
Topics: Amino Acids; Carbon Isotopes; Cystathionine; Cysteine; Homocysteine; Homoserine; Methionine; Seeds; Sulfides; Sulfur Isotopes | 1972 |
Hyperaminoacidemia in rabbits treated with 6-azauridine triacetate.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Antimetabolites; Cystathionine; Cysteine; Homocysteine; Male; Methionine; Nucleosides; Rabbits | 1971 |
Differential cyst(e)ine requirements in human T and B lymphoblastoid cell lines.
Topics: B-Lymphocytes; Cell Line; Concanavalin A; Cystathionine; Cysteine; Cystine; Herpesvirus 4, Human; Homocysteine; Humans; Lymphocyte Activation; Staphylococcal Protein A; T-Lymphocytes | 1982 |
The effects of chronic isoniazid intoxication on motor end plate sprouting in rat sternocostalis muscle and on responses to partial denervation and local botulinum toxin.
Topics: Animals; Botulinum Toxins; Cystathionine; Cysteine; Cystine; Drug Interactions; Female; Glutathione; Homocysteine; Isoniazid; Motor Endplate; Neuromuscular Junction; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains | 1984 |
Direct homocysteine biosynthesis from O-succinylhomoserine in Escherichia coli: an alternate pathway that bypasses cystathionine.
Topics: Carbon-Oxygen Lyases; Cystathionine; Cystathionine gamma-Lyase; Escherichia coli; Homocysteine; Homoserine; Lyases; Mutation | 1983 |
Cloning, purification, and characterization of beta-cystathionase from Escherichia coli.
Topics: Amino Acids; Cloning, Molecular; Cystathionine; Escherichia coli; Homocysteine; Kinetics; Lyases; Molecular Weight; Plasmids; Pyridoxal Phosphate | 1982 |
Cysteine and homocysteine synthesis in Saccharomycopsis lipolytica; identification and characterization of two cysteine synthases.
Topics: Ascomycota; Carbon-Oxygen Lyases; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Cysteine Synthase; Homocysteine; Lyases; Multienzyme Complexes; Mutation; Pyridoxal Phosphate; Saccharomyces cerevisiae Proteins; Saccharomycopsis; Substrate Specificity | 1982 |
Effect of 1-aminoproline on methionine metabolism in rats.
Topics: Animals; Cystathionine; Homocysteine; Male; Methionine; Proline; Rats; Stereoisomerism; Sulfoxides | 1981 |
Involvement of the cystathionine pathway in the biosynthesis of glutathione by isolated rat hepatocytes.
Topics: Alkynes; Animals; Cystathionine; Cystathionine gamma-Lyase; Glutathione; Glycine; Homocysteine; In Vitro Techniques; Kinetics; Liver; Male; Methionine; Rats | 1980 |
Carbon tetrachloride-induced hepatic injury is associated with global DNA hypomethylation and homocysteinemia: effect of S-adenosylmethionine treatment.
Topics: Animals; Carbon Tetrachloride; Cystathionine; DNA; Folic Acid; Homocysteine; Liver; Liver Cirrhosis, Experimental; Male; Methionine; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1995 |
Evidence that homocysteine is an independent risk factor for atherosclerosis in hyperlipidemic patients.
Topics: Aged; Analysis of Variance; Arteriosclerosis; Coronary Disease; Cystathionine; Folic Acid; Homocysteine; Humans; Hyperlipidemias; Methylmalonic Acid; Middle Aged; Pyridoxine; Risk Factors | 1995 |
Methionine biosynthesis in higher plants. I. Purification and characterization of cystathionine gamma-synthase from spinach chloroplasts.
Topics: Alkynes; Carbon-Oxygen Lyases; Carbon-Sulfur Lyases; Cell Compartmentation; Chloroplasts; Cystathionine; Glycine; Homocysteine; Homoserine; Kinetics; Lyases; Methionine; Molecular Weight; Pargyline; Plant Leaves; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry; Spinacia oleracea | 1995 |
Methionine biosynthesis in higher plants. II. Purification and characterization of cystathionine beta-lyase from spinach chloroplasts.
Topics: Aminobutyrates; Cell Compartmentation; Chloroplasts; Cystathionine; Homocysteine; Kinetics; Lyases; Methionine; Plant Leaves; Pyridoxal Phosphate; Pyruvates; Pyruvic Acid; Spectrophotometry; Spinacia oleracea | 1995 |
Transsulfuration depends on heme in addition to pyridoxal 5'-phosphate. Cystathionine beta-synthase is a heme protein.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Escherichia coli; Heme; Hemeproteins; Homocysteine; Humans; Kinetics; Liver; Pyridoxal Phosphate; Rats; Recombinant Proteins; Serine; Spectrophotometry; Sulfur | 1994 |
Identification of new cystathionine mono-oxo acids, S-(3-oxo-3-carboxy-n-propyl) cysteine and S-(2-oxo-2-carboxyethyl) homocysteine, in the urine of a patient with cystathioninuria.
Topics: Amino Acid Metabolism, Inborn Errors; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Keto Acids | 1993 |
Liver DNA and RNA metabolism in rats fed diets lacking methionine plus cysteine with or without restricted energy.
Topics: Animal Feed; Animals; Body Weight; Cell Nucleus; Cell Size; Cystathionine; Cysteine; Deoxyribonucleases; Diet; DNA; Eating; Energy Metabolism; Homocysteine; Liver; Male; Methionine; Methylation; Organ Size; Proteins; Rats; Rats, Wistar; Ribonucleases; RNA; Solubility | 1995 |
The effect of a subnormal vitamin B-6 status on homocysteine metabolism.
Topics: Administration, Oral; Adult; Asthma; Bronchodilator Agents; Cystathionine; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Pyridoxine; Theophylline; Vitamin B 6 Deficiency | 1996 |
Enhanced levels of biochemical markers for cobalamin deficiency in totally gastrectomized rats: uncoupling of the enhancement from the severity of spongy vacuolation in spinal cord.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Pernicious; Animals; Bacteria, Anaerobic; Citrates; Cystathionine; Disease Models, Animal; Erythromycin; Gastrectomy; Homocysteine; Humans; Intestines; Lincomycin; Male; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Postgastrectomy Syndromes; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Diseases; Vacuoles; Vitamin B 12; Vitamin B 12 Deficiency | 1997 |
Increased concentrations of homocysteine in the cerebrospinal fluid in patients with fibromyalgia and chronic fatigue syndrome.
Topics: Adult; Cystathionine; Fatigue Syndrome, Chronic; Female; Fibromyalgia; Homocysteine; Humans; Methionine; Middle Aged; Models, Biological; Vitamin B 12 | 1997 |
Cellular mechanisms of resistance to chronic oxidative stress.
Topics: Animals; Antioxidants; bcl-2-Associated X Protein; Biological Transport; Catalase; Cell Line; Cell Survival; Cystathionine; Cystine; Drug Resistance; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Heat-Shock Proteins; Homocysteine; Mice; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Oxidative Stress; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Time Factors; Up-Regulation | 1998 |
Evidence of altered homocysteine metabolism in chronic renal failure.
Topics: Arteriosclerosis; Citrates; Creatinine; Cystathionine; Cysteine; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methionine; Methylmalonic Acid; Middle Aged; Renal Dialysis; Risk Factors; Vitamins | 1999 |
The quantitatively important relationship between homocysteine metabolism and glutathione synthesis by the transsulfuration pathway and its regulation by redox changes.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cystathionine; Cystathionine beta-Synthase; Glutathione; Hepatocytes; Homocysteine; Humans; Intracellular Fluid; Oxidation-Reduction; Oxidative Stress; Sulfur; tert-Butylhydroperoxide; Tumor Cells, Cultured | 2000 |
Role of homocysteine, cystathionine and methylmalonic acid measurement for diagnosis of vitamin deficiency in high-aged subjects.
Topics: Adult; Aged; Cystathionine; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Kidney; Male; Methylmalonic Acid; Middle Aged; Models, Chemical; Pyridoxine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2000 |
Occurrence of transsulfuration in synthesis of L-homocysteine in an extremely thermophilic bacterium, Thermus thermophilus HB8.
Topics: Culture Media; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Cysteine Synthase; Gene Expression Regulation, Bacterial; Homocysteine; Lyases; Methionine; S-Adenosylmethionine; Sulfur; Temperature; Thermus thermophilus | 2001 |
Disposition of homocysteine in subjects heterozygous for homocystinuria due to cystathionine beta-synthase deficiency: relationship between genotype and phenotype.
Topics: Adolescent; Adult; Aged; Cystathionine; Cystathionine beta-Synthase; DNA; Female; Genotype; Heterozygote; Homocysteine; Homocystinuria; Humans; Male; Methionine; Middle Aged; Mutation; Phenotype; Reference Values | 2001 |
Homocysteine metabolism in children with Down syndrome: in vitro modulation.
Topics: Adenosine; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cystathionine beta-Synthase; Cysteine; DNA Methylation; Down Syndrome; Glutathione; Homocysteine; Humans; Leucovorin; Lymphocytes; Methionine; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Superoxide Dismutase; Thymidine; Vitamin B 12 | 2001 |
Biosynthesis of methionine from homocysteine, cystathionine and homoserine plus cysteine by mixed rumen microorganisms in vitro.
Topics: Amino Acids; Aminobutyrates; Anaerobiosis; Animals; Bacteria; Culture Media; Cystathionine; Cysteine; Eukaryota; Goats; Homocysteine; Homoserine; Methionine; Rumen; Temperature | 2001 |
The reaction of yeast cystathionine beta-synthase is rate-limited by the conversion of aminoacrylate to cystathionine.
Topics: Cystathionine; Cystathionine beta-Synthase; Feedback; Homocysteine; Kinetics; Models, Chemical; Saccharomyces cerevisiae; Serine; Spectrophotometry | 2001 |
Genetic defects as important factors for moderate hyperhomocysteinemia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Age Factors; Aged; Aged, 80 and over; Cystathionine; DNA Mutational Analysis; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Protein Binding; Risk Factors; Sex Factors; Vitamin B 12; Vitamin B 6 | 2001 |
Homocysteine, cystathionine, methylmalonic acid and B-vitamins in patients with renal disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Cystathionine; Female; Homocysteine; Humans; Immunoassay; Kidney Diseases; Kidney Transplantation; Male; Methylmalonic Acid; Middle Aged; Renal Dialysis; Vitamin B Complex | 2001 |
Does a single vitamin B-supplementation induce functional vitamin B-deficiency?
Topics: Adult; Cystathionine; Cysteine; Dietary Supplements; Folic Acid; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Methionine; Methylmalonic Acid; Middle Aged; Models, Biological; Pilot Projects; Time Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2001 |
Metabolism of amino acids in cats with severe cobalamin deficiency.
Topics: Amino Acids; Animals; Cat Diseases; Cats; Cystathionine; Cysteine; Female; Gastrointestinal Diseases; Homocysteine; Immunoassay; Male; Methionine; Methylmalonic Acid; Statistics, Nonparametric; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Yeast cystathionine beta-synthase reacts with L-allothreonine, a non-natural substrate, and L-homocysteine to form a new amino acid, 3-methyl-L-cystathionine.
Topics: Circular Dichroism; Cystathionine; Cystathionine beta-Synthase; Homocysteine; Kinetics; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Saccharomyces cerevisiae; Serine; Spectrophotometry; Substrate Specificity; Threonine | 2002 |
Stopped-flow kinetic analysis of the reaction catalyzed by the full-length yeast cystathionine beta-synthase.
Topics: Catalysis; Cystathionine; Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Heme; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae; Serine; Spectrophotometry; Time Factors | 2002 |
Elevated plasma total homocysteine in severe methionine adenosyltransferase I/III deficiency.
Topics: Adolescent; Child; Child, Preschool; Cystathionine; Cystathionine beta-Synthase; Female; Homocysteine; Humans; Infant; Isoenzymes; Lyases; Male; Methionine; Methionine Adenosyltransferase | 2002 |
Synthesis of optically active homocysteine from methionine and its use in preparing four stereoisomers of cystathionine.
Topics: Cystathionine; Homocysteine; Methionine; Optical Rotation; Stereoisomerism | 2002 |
Molecular characterization of a cystathionine beta-synthase gene, CBS1, in Magnaporthe grisea.
Topics: Amino Acid Sequence; Cystathionine; Cystathionine beta-Synthase; Genes, Fungal; Homocysteine; Magnaporthe; Mitochondrial Proteins; Molecular Sequence Data; Plant Diseases; Saccharomyces cerevisiae Proteins; Sequence Alignment; Sequence Analysis, Protein; Trans-Activators; Vitamin B 12 | 2002 |
Kinetics of the yeast cystathionine beta-synthase forward and reverse reactions: continuous assays and the equilibrium constant for the reaction.
Topics: Catalysis; Cystathionine; Cystathionine beta-Synthase; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Recombinant Proteins; Saccharomyces cerevisiae Proteins; Sequence Deletion; Serine; Spectrophotometry; Substrate Specificity | 2003 |
Serum levels of total homocysteine, homocysteine metabolites and of advanced glycation end-products (AGEs) in patients after renal transplantation.
Topics: Adult; Arginine; Coronary Disease; Cystathionine; Female; Glycation End Products, Advanced; Homocysteine; Humans; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Kidney Transplantation; Logistic Models; Lysine; Male; Methylmalonic Acid; Middle Aged; Risk Factors | 2003 |
Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
Topics: Amino Acid Sequence; Archaeal Proteins; Binding Sites; Cystathionine; Cysteine; Cysteine Synthase; Desulfurococcaceae; Dithiothreitol; Enzyme Activation; Enzyme Stability; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Sequence Homology, Amino Acid; Serine; Substrate Specificity; Sulfides; Temperature | 2003 |
[Cysteine, homocysteine, cystathionine & cysteinamine as necrotropic liver protective substances, combined with glucose & fructose].
Topics: Catabolite Repression; Cystathionine; Cysteamine; Cysteine; Fructose; Glucose; Homocysteine; Humans; Liver; Mercaptoethylamines | 1957 |
Accumulation of cystathionine in a homocysteine requiring mutant of Aerobacter aerognes.
Topics: Amino Acids; Cystathionine; Cysteine; Enterobacter; Enterobacter aerogenes; Homocysteine | 1962 |
CYSTATHIONINE CLEAVAGE ENZYMES OF NEUROSPORA.
Topics: Amino Acid Oxidoreductases; Amino Acids; Butyrates; Cystathionine; Cysteine; Homocysteine; Iodoacetates; L-Lactate Dehydrogenase; Maleates; Neurospora; Pyridoxal Phosphate; Pyruvates; Research; Serine; Sulfhydryl Compounds | 1964 |
O-SUCCINYLHOMOSERINE AS AN INTERMEDIATE IN THE SYNTHESIS OF CYSTATHIONINE BY ESCHERICHIA COLI.
Topics: Adenosine Triphosphate; Amino Acids; Chromatography; Coenzyme A; Cystathionine; Cysteine; Escherichia coli; Glucose; Homocysteine; Homoserine; Hot Temperature; Methionine; Research; Streptococcus; Succinates | 1964 |
A mathematical model of the methionine cycle.
Topics: Animals; Computational Biology; Cystathionine; Homocysteine; Methionine; Models, Biological; S-Adenosylhomocysteine; S-Adenosylmethionine | 2004 |
The biosynthesis of cysteine and homocysteine in Methanococcus jannaschii.
Topics: Cystathionine; Cysteine; Gas Chromatography-Mass Spectrometry; Homocysteine; Methanococcus | 2003 |
Copper-mediated LDL oxidation by homocysteine and related compounds depends largely on copper ligation.
Topics: Copper; Cystathionine; Cysteine; Homocysteine; Homocystine; Humans; Lipoproteins, LDL; Malondialdehyde; Oxidation-Reduction; Serum Albumin; Time Factors | 2004 |
CSF-methionine is elevated in psychotic patients.
Topics: Adult; Biomarkers; Cystathionine; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Psychotic Disorders; Sex Factors | 2004 |
Response of homocysteine, cystathionine, and methylmalonic acid to vitamin treatment in dialysis patients.
Topics: Aged; Aged, 80 and over; Cystathionine; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylmalonic Acid; Middle Aged; Renal Dialysis; Vitamin B 12; Vitamin B 6 | 2005 |
Alteration of homocysteine catabolism in pre-eclampsia, HELLP syndrome and placental insufficiency.
Topics: Cystathionine; Cystatin C; Cystatins; Female; Folic Acid; HELLP Syndrome; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Methylmalonic Acid; Oxidative Stress; Placental Insufficiency; Pre-Eclampsia; Pregnancy; Severity of Illness Index; Uric Acid; Vitamin B 12; Vitamin B 6 | 2004 |
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2004 |
Cellular uptake of vitamin B12 in patients with chronic renal failure.
Topics: Adult; Aged; Cells, Cultured; Cystathionine; Female; Homocysteine; Humans; Kidney Failure, Chronic; Leukocytes, Mononuclear; Male; Methylmalonic Acid; Middle Aged; Vitamin B 12 | 2005 |
Disturbed homocysteine and methionine cycle intermediates S-adenosylhomocysteine and S-adenosylmethionine are related to degree of renal insufficiency in type 2 diabetes.
Topics: Aged; Cystathionine; Cysteine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Folic Acid; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Male; Methionine; Methylmalonic Acid; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcobalamins; Vitamin B 12; Vitamin B 6 | 2005 |
Inhibitory effect of copper on cystathionine beta-synthase activity: protective effect of an analog of the human albumin N-terminus.
Topics: Albumins; Copper; Cystathionine; Cystathionine beta-Synthase; Homocysteine; Humans; Recombinant Proteins | 2005 |
Modulation of cadmium chloride toxicity by sulphur amino acids in hepatoma cells.
Topics: Cadmium Chloride; Carcinoma, Hepatocellular; Cystathionine; Cysteine; Cytoprotection; Glutathione; Homocysteine; Humans; Tumor Cells, Cultured | 2006 |
Two newborns with nutritional vitamin B12 deficiency: challenges in newborn screening for vitamin B12 deficiency.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Anemia, Pernicious; Autoimmune Diseases; Biomarkers; Carnitine; Citrates; Cystathionine; False Negative Reactions; Female; Gastric Bypass; Heterozygote; Homocysteine; Humans; Hydroxocobalamin; Infant Food; Infant, Newborn; Malabsorption Syndromes; Male; Mass Spectrometry; Maternal-Fetal Exchange; Methylmalonic Acid; Neonatal Screening; Pregnancy; Pregnancy Complications; Vitamin B 12 Deficiency | 2005 |
Screening of toxicity biomarkers for methionine excess in rats.
Topics: Amino Acids; Analysis of Variance; Animals; Bilirubin; Biomarkers; Cystathionine; Diet; Gas Chromatography-Mass Spectrometry; Glycine; Hemolysis; Homocysteine; Iron; Male; Methionine; Rats; Rats, Inbred F344; Serine; Spleen | 2006 |
A clinical and laboratory evaluation of methionine cycle-transsulfuration and androgen pathway markers in children with autistic disorders.
Topics: Androgens; Autistic Disorder; Biomarkers; Child; Child, Preschool; Cystathionine; Cysteine; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; Glutathione; Homocysteine; Humans; Male; Methionine; Models, Biological; Signal Transduction; Sulfurtransferases; Testosterone | 2006 |
Hyperhomocysteinemia decreases circulating high-density lipoprotein by inhibiting apolipoprotein A-I Protein synthesis and enhancing HDL cholesterol clearance.
Topics: Aged; Animals; Apolipoprotein A-I; Apolipoproteins E; Biological Transport; Cells, Cultured; Cholesterol; Cholesterol, HDL; Coronary Artery Disease; Cystathionine; Hepatocytes; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, HDL; Male; Mice; Mice, Knockout; Middle Aged | 2006 |
Conversion of methionine to cysteine in Bacillus subtilis and its regulation.
Topics: Bacillus subtilis; Bacterial Proteins; Carbon-Oxygen Lyases; Cystathionine; Cystathionine beta-Synthase; Cysteine; Gene Expression Regulation, Bacterial; Genes, Bacterial; Homocysteine; Lyases; Methionine; Operon; Promoter Regions, Genetic; Serine; Substrate Specificity | 2007 |
Biomarkers of folate and vitamin B12 are related in blood and cerebrospinal fluid.
Topics: Adult; Aged; Aging; Biomarkers; Cystathionine; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12 | 2007 |
A new synthesis of S-(beta-amino-beta-carboxyethyl) homocysteine (cystathionine) and S-bis(gamma-amino-gamma -carboxypropyl) sulfide (homolanthionine).
Topics: Cystathionine; Homocysteine; Sulfides | 1948 |
In Helicobacter pylori, LuxS is a key enzyme in cysteine provision through a reverse transsulfuration pathway.
Topics: Bacterial Proteins; Carbon-Sulfur Lyases; Computational Biology; Culture Media; Cystathionine; Cysteine; DNA, Bacterial; Gene Knockout Techniques; Gene Order; Gene Transfer, Horizontal; Gram-Positive Bacteria; Helicobacter pylori; Homocysteine; Metabolic Networks and Pathways; Sequence Analysis, DNA; Sulfur | 2010 |
Residue N84 of yeast cystathionine beta-synthase is a determinant of reaction specificity.
Topics: Alanine; Aspartic Acid; Catalysis; Cystathionine; Cystathionine beta-Synthase; Histidine; Homocysteine; Kinetics; Mutation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Substrate Specificity; Time Factors; Tryptophan | 2010 |
Impaired homocysteine transsulfuration is an indicator of alcoholic liver disease.
Topics: Adult; Aged; Alcoholism; Aminobutyrates; Biomarkers; Case-Control Studies; Cystathionine; Disease Progression; Female; Homocysteine; Humans; Liver; Liver Cirrhosis, Alcoholic; Liver Diseases, Alcoholic; Male; Methionine; Middle Aged; Sulfur; Young Adult | 2010 |
Pre-steady-state kinetic analysis of enzyme-monitored turnover during cystathionine β-synthase-catalyzed H(2)S generation.
Topics: Cystathionine; Cystathionine beta-Synthase; Cysteine; Homocysteine; Hydrogen Sulfide; Kinetics; Models, Chemical; Protein Conformation; Saccharomyces cerevisiae Proteins | 2011 |
Effects of gamma-ray-induced free radicals on the metal content and amino acid composition of human metallothionein-1.
Topics: Butyrates; Cystathionine; Cysteine; Gamma Rays; Homocysteine; Humans; Metallothionein; Methionine; Serine; Zinc | 2011 |
Vision changes after spaceflight are related to alterations in folate- and vitamin B-12-dependent one-carbon metabolism.
Topics: Adult; Astronauts; Carbon Dioxide; Citrates; Cystathionine; Female; Folic Acid; Homocysteine; Humans; Male; Metabolic Networks and Pathways; Methylmalonic Acid; Middle Aged; Models, Biological; Refraction, Ocular; Space Flight; Vision Disorders; Vitamin B 12 | 2012 |
Methylation capacity in children with severe cerebral palsy.
Topics: Betaine; Biomarkers; Case-Control Studies; Cerebral Palsy; Child; Child, Preschool; Choline; Cystathionine; DNA Methylation; Erythrocyte Indices; Erythrocyte Membrane; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Queensland; Severity of Illness Index; Uric Acid | 2012 |
Novel thiol- and thioether-containing amino acids: cystathionine and homocysteine families.
Topics: Aspartic Acid; Cystathionine; Glutamic Acid; Homocysteine; Molecular Structure | 2013 |
Plasma sulfur amino acids and stearoyl-CoA desaturase activity in two Caucasian populations.
Topics: Adipose Tissue; Aged; Aged, 80 and over; Amino Acids, Sulfur; Cohort Studies; Cross-Sectional Studies; Cystathionine; Cysteine; Diet; Dipeptides; Exercise; Fatty Acids; Female; Glutathione; Homocysteine; Humans; Male; Methionine; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Stearoyl-CoA Desaturase; Surveys and Questionnaires; White People | 2013 |
Oral exposure to the anti-pyridoxine compound 1-amino D-proline further perturbs homocysteine metabolism through the transsulfuration pathway in moderately vitamin B₆ deficient rats.
Topics: Animals; Asymptomatic Diseases; Biomarkers; Cystathionine; Cystathionine gamma-Lyase; Diet; Disease Models, Animal; Disease Progression; Flax; Homocysteine; Hyperhomocysteinemia; Liver; Male; Non-alcoholic Fatty Liver Disease; Proline; Pyridoxal Phosphate; Pyridoxine; Random Allocation; Rats, Sprague-Dawley; Seeds; Vitamin B 6; Vitamin B 6 Deficiency | 2015 |
Propargylglycine inhibits hypotaurine/taurine synthesis and elevates cystathionine and homocysteine concentrations in primary mouse hepatocytes.
Topics: Alkynes; Animals; Cells, Cultured; Cystathionine; Cysteine Dioxygenase; Female; Glycine; Hepatocytes; Homocysteine; Male; Mice; Mice, Knockout; Primary Cell Culture; Taurine | 2015 |
Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users.
Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Carbon; Contraceptives, Oral; Cystathionine; Dietary Supplements; Female; Glycine; Homocysteine; Humans; Kynurenine; Leucine; Methionine; Methylamines; Multivariate Analysis; Pyridoxal Phosphate; Pyridoxine; Serine; Tryptophan; Vitamin B 6 Deficiency; Young Adult | 2015 |
The association of single nucleotide polymorphisms of the maternal cystathionine-β-synthase gene with early-onset preeclampsia.
Topics: Adult; Biomarkers; Blood Pressure; Case-Control Studies; Cystathionine; Cystathionine beta-Synthase; Cysteine; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Gestational Age; Homocysteine; Humans; Phenotype; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Protective Factors; Risk Factors | 2016 |
A disrupted transsulphuration pathway results in accumulation of redox metabolites and induction of gametocytogenesis in malaria.
Topics: Animals; Culture Media; Cystathionine; Cysteine; Disease Models, Animal; Erythrocytes; Glutathione; Homocysteine; Humans; Malaria; Mass Spectrometry; Metabolic Networks and Pathways; Mice; Oxidation-Reduction; Plasmodium falciparum; Protozoan Proteins; Sulfur; Transcription Factors; Transcriptional Activation | 2017 |
Effects of high ambient temperature on plasma metabolomic profiles in chicks.
Topics: Amino Acids, Sulfur; Animals; Chickens; Cystathionine; Cysteine; Cystine; Environmental Exposure; Gas Chromatography-Mass Spectrometry; Homocysteine; Hot Temperature; Kynurenine; Molecular Weight; Niacinamide; Oxidative Stress; Quinolinic Acid; Taurine; Tryptophan | 2018 |
The high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) may explain naked mole-rat's distinct methionine metabolite profile compared to mouse.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Enzyme Activation; Homocysteine; Homocystinuria; Methionine; Mice; Mole Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 2018 |
Identification and characterization of Helicobacter pylori O-acetylserine-dependent cystathionine β-synthase, a distinct member of the PLP-II family.
Topics: Bacterial Proteins; Binding Sites; Catalytic Domain; Cystathionine; Cystathionine beta-Synthase; Enzyme Stability; Helicobacter pylori; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methionine; Serine; Substrate Specificity | 2019 |
[Effects of methionine on the activity of cystathionine-β-synthase].
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine; Cystathionine beta-Synthase; Homocysteine; Liver; Male; Methionine; Rats; Rats, Wistar | 2019 |
The concomitant lower concentrations of vitamins B6, B9 and B12 may cause methylation deficiency in autistic children.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Autism Spectrum Disorder; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cystathionine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Male; Mass Spectrometry; Methionine; Methylation; Mutation; Oxidation-Reduction; Phenotype; Vitamin B 12; Vitamin B 6 | 2019 |
Assessing computational predictions of the phenotypic effect of cystathionine-beta-synthase variants.
Topics: Amino Acid Substitution; Computational Biology; Cystathionine; Cystathionine beta-Synthase; Homocysteine; Humans; Phenotype; Precision Medicine | 2019 |
Blockade of the trans-sulfuration pathway in acute pancreatitis due to nitration of cystathionine β-synthase.
Topics: Animals; Ceruletide; Cystathionine; Cystathionine beta-Synthase; Cysteine; Disease Models, Animal; Glutathione; Homocysteine; Male; Mice; Nitric Oxide Synthase Type II; Pancreatitis; S-Adenosylmethionine; Up-Regulation | 2020 |
L-Cystathionine Protects against Homocysteine-Induced Mitochondria-Dependent Apoptosis of Vascular Endothelial Cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cystathionine; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Protective Agents | 2019 |
Cystathionine β-synthase is involved in cysteine biosynthesis and H
Topics: Biocatalysis; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; DNA, Complementary; Genes, Protozoan; Heme; Homocysteine; Hydrogen Sulfide; Kinetics; Serine; Toxoplasma | 2020 |
Catalytic specificity of the Lactobacillus plantarum cystathionine γ-lyase presumed by the crystallographic analysis.
Topics: Catalysis; Crystallography, X-Ray; Cystathionine; Cystathionine gamma-Lyase; Homocysteine; Lactobacillus plantarum; Serine; Substrate Specificity | 2020 |
A sensitive UPLC-MS/MS method for simultaneous quantification of one-carbon metabolites & co-factors in human plasma.
Topics: Carbon; Chromatography, High Pressure Liquid; Chromatography, Liquid; Colorectal Neoplasms; Cystathionine; Homocysteine; Humans; Methionine; Tandem Mass Spectrometry | 2022 |
The Associations of Habitual Intake of Sulfur Amino Acids, Proteins and Diet Quality with Plasma Sulfur Amino Acid Concentrations: The Maastricht Study.
Topics: Amino Acids, Sulfur; Cardiovascular Diseases; Cross-Sectional Studies; Cystathionine; Cysteine; Diabetes Mellitus, Type 2; Diet; Female; Homocysteine; Humans; Methionine; Obesity; Taurine | 2023 |
A Methionine-Portioning-Based Medical Nutrition Therapy with Relaxed Fruit and Vegetable Consumption in Patients with Pyridoxine-Nonresponsive Cystathionine-β-Synthase Deficiency.
Topics: Cystathionine; Cystathionine beta-Synthase; Diet, Protein-Restricted; Fruit; Homocysteine; Homocystinuria; Humans; Methionine; Pyridoxine; Racemethionine; Vegetables | 2023 |