homocysteine and cystathionine

homocysteine has been researched along with cystathionine in 143 studies

Research

Studies (143)

TimeframeStudies, this research(%)All Research%
pre-199049 (34.27)18.7374
1990's15 (10.49)18.2507
2000's49 (34.27)29.6817
2010's24 (16.78)24.3611
2020's6 (4.20)2.80

Authors

AuthorsStudies
Dow, MJ; Kokkeler, SC; Miller, LT1
Halaseh, A; McConnell, WB; Nigam, SN1
Beaton, JM1
Grabski, J; Paszewski, A2
Hamilton, H; Iles, JF1
Miller, JW; Selhub, J1
Harvey, PR; Ilson, RG; Strasberg, SM1
Allard, D; Ceballos, I; Chadefaux, B; Jérôme, H1
Finkelstein, JD; Harris, BJ; Martin, JJ1
Duerre, JA; Wallwork, JC1
Brodie, AE; Reed, DJ1
Chatagner, F; de Billy, G; Ipaktchi, M; Lefauconnier, JM; Portemer, C1
Flavin, M; Savin, MA1
Beaton, JM; Bradley, RJ; Bridgers, WF; McClain, LD; Pegram, GV; Smythies, JR1
Jacoby, LB; Littlefield, JW1
Finkelstein, JD; Harris, BJ; Kyle, WE1
Cello, JP; Finkelstein, JD; Kyle, WE1
Bourel, M; Le Guilly, Y; Lenoir, P; Simon, M1
Corwin, LM; Rothman, SW1
Paszewski, A; Pieniazek, N; Stepień, PP1
Collins, JM; Monty, KJ1
Greene, RC; Kung, HF; Spears, C; Weissbach, H; Williams, RD1
Finkelstein, JD2
Hakami, N; Sagerson, RN; Scott, CR; Teng, CC1
Coignet, J; Laurent, B1
Boucher, Y; Lachance, RA; Paquin, R1
Barboza, V; Fernandez, E; Pulgar, J1
Jung, G; Ottnad, M; Rimpler, M1
Florentiev, VL; Goryachenkova, EV; Polyakova, LA; Yefremova, LL1
Gaull, G; Schaffner, F; Sturman, JA1
Gaull, GE; Pascal, TA; Sturman, JA; Tallan, HH1
Hirayama, K; Ikegami, T; Kodama, H; Mizuhara, S1
Hodgson, E; Rock, GC; Sharma, GK1
Chatagner, F; Deme, D1
McCully, KS1
Ngo, TT; Shargool, PD1
Keiser, HR; Lovenberg, W; Sjoerdsma, A; Slavik, M1
Carson, DA; Kamatani, N1
Cavanagh, JB; Kemplay, S1
Hong, JS; Simon, M1
Dwivedi, CM; Ragin, RC; Uren, JR1
Morzycka, E; Paszewski, A1
Kimoto, M; Ogawa, T; Sasaoka, K1
Beatty, PW; Reed, DJ1
Alonso-Aperte, E; Alvarez, L; Caballería, J; Deulofeu, R; Gassó, M; Mato, JM; Rodés, J; Rubio, M; Varela-Moreiras, G1
Allen, RH; Joosten, E; Lindenbaum, J; Naurath, HJ; Riezler, R; Stabler, SP1
Glueck, CJ; Lang, JE; Shaw, P; Sieve-Smith, L; Tracy, T; Wang, Y1
Douce, R; Droux, M; Ravanel, S2
Bukovska, G; Kery, V; Kraus, JP1
Kodama, H; Kurashige, T; Okada, T; Sugahara, K; Takechi, T; Wakiguchi, H1
González-Fernández, M; Rey de Viñas, JL; Sandoval, MC1
Allen, RH; Delport, R; Riezler, R; Stabler, SP; Ubbink, JB; van der Merwe, A; Vermaak, WJ1
Allen, RH; Buccellato, FR; Lindenbaum, J; Lorenzini, EC; Morabito, A; Scalabrino, G; Tredici, G1
Abrahamsson, L; Andersson, M; Bagby, J; Dyrehag, LE; Gottfries, CG; Regland, B1
Chambers, D; Dargusch, R; Davis, J; Maher, P; Sagara, Y; Schubert, D1
Allen, RH; Cohen, JA; Estacio, R; Jeffers, BW; Schrier, RW; Stabler, SP1
Graefe, U; Henning, BF; Langer, K; Raidt, H; Riezler, R; Tepel, M; Zidek, W1
Berthold, HK; Brensing, KA; Look, MP; Reichel, C; Riezler, R; Rockstroh, JK; Sauerbruch, T; Spengler, U; Stabler, SP1
Banerjee, R; Cranford, MR; Mosharov, E1
Bodis, M; Geisel, J; Herrmann, W; Knapp, JP; Müller, A; Schorr, H; Stein, G1
Goto, K; Ichioka, K; Iwama, T; Mizuno, Y; Yamagata, S1
Følling, I; Guttormsen, AB; Kim, CE; Kruger, WD; Ose, L; Refsum, H; Ueland, PM1
Fukagawa, NK; MacCoss, MJ; Matthews, DE1
Chango, A; James, SJ; Melnyk, S; Pogribna, M; Pogribny, I; Yi, P1
Chambers, JC; Doré, CJ; Kooner, JS; Refsum, H; Ueland, PM; Wright, M1
Gromeier, S; Herrmann, W; Julius, U; Pietzsch, J; Schorr, H1
Onodera, R; Or-Rashid, MM; Wadud, S1
Dunn, MF; Jhee, KH; McPhie, P; Miles, EW; Niks, D2
Bodis, M; Geisel, J; Herrmann, W; Hübner, U; Knapp, JP; Schorr, H; Zimbelmann, I1
Geisel, J; Herrmann, W; Riegel, W; Schorr, H1
Naurath, HJ; Pütter, S; Riezler, R; Ubbink, JB1
Allen, RH; Berthold, HK; Look, MP; Riezler, R; Rockstroh, JK; Sauerbruch, T; Schliefer, K; Stabler, SP1
Ruaux, CG; Steiner, JM; Williams, DA1
Banerjee, R; Taoka, S1
Allen, RH; Kraus, JP; Mudd, SH; Oliveriusova, J; Stabler, SP; Steegborn, C; Wagner, C; Wahl, MC1
Kanemoto, N; Kinda, T; Nakagawa, K; Shiraiwa, T; Yamamoto, H1
Hamer, JE; Hamer, L; Lo, SC1
Aitken, SM; Kirsch, JF2
Busch, M; Franke, S; Kientsch-Engel, R; Müller, A; Sommer, M; Stein, G1
Ishikawa, K; Mino, K1
EGER, W1
HAROLD, FM1
FLAVIN, M; SLAUGHTER, C1
ROWBURY, RJ; WOODS, DD1
Nijhout, HF; Reed, MC; Sparks, R; Ulrich, CM1
White, RH1
Guttormsen, AB; Refsum, H; Solheim, E1
Nakano, E; Powers, HJ; Williams, NH; Williamson, MP1
Busch, M; Franke, C; Franke, S; Klemm, A; Lang, D; Müller, A; Passlick-Deetjen, J; Stein, G1
Abrahamsson, L; Blennow, K; Gottfries, CG; Grenfeldt, B; Regland, B1
Bleie, Ø; Guttormsen, AB; Nexo, E; Nordrehaug, JE; Nygård, O; Refsum, H; Schneede, J; Ueland, PM; Vollset, SE1
Herrmann, W; Köhler, H; Kuhlmann, MK; Obeid, R1
Geisel, J; Herrmann, W; Hübner, U; Koch, I; Obeid, R; Retzke, U1
Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA1
Herrmann, W; Kirsch, CM; Kuhlmann, M; Obeid, R1
Allen, R; Boger, R; Doshi, S; Goodfellow, J; Lewis, M; McDowell, I; Moat, S; Newcombe, R; Stabler, S1
Fowler, B; Herrmann, W; Kuhlmann, MK; Makowski, J; Obeid, R; Schorr, H1
Bar-Or, D; Kraus, JP; Rael, LT; Thomas, GW1
Fotakis, G; Timbrell, JA1
Campbell, CD; Ficicioglu, C; Ganesh, J1
Amao, M; Kawamata, Y; Kimura, T; Kodama, R; Sakai, R; Toue, S1
Garlick, PJ1
Geier, DA; Geier, MR1
Chan, L; Durante, W; Gaubatz, J; Hui, R; Jiang, X; Li, Z; Liao, D; Pownall, HJ; Schafer, AI; Tan, H; Wang, H; Yang, F; Yang, X1
Auger, S; Barzu, O; Danchin, A; Hullo, MF; Martin-Verstraete, I; Soutourina, O; Yvon, M1
Becker, G; Fassbender, K; Herrmann, W; Kasoha, M; Knapp, JP; Kostopoulos, P; Obeid, R1
Baggott, JE; Tamura, T2
STEKOL, JA1
Atherton, JC; Barrett, DA; Doherty, NC; Halliday, NM; Hardie, KR; Shen, F; Winzer, K1
Aitken, SM; Hopwood, EM; Lodha, PH; Manders, AL1
Albanese, A; Bowlus, CL; Devaraj, S; French, SW; Gregory, JF; Halsted, CH; Medici, V; Panacek, EA; Peerson, JM; Rahim, N; Richards, JR; Rossaro, L; Stabler, SP; Virata, MC1
Ballou, DP; Banerjee, R; Singh, S1
Goossens, L1
Ericson, K; Gibson, CR; Heer, M; Mader, TH; Ploutz-Snyder, R; Smith, SM; Zwart, SR1
Boyd, RN; Davies, PS; Moxon-Lester, L; Obeid, R; Schoendorfer, NC; Sharp, N; Vitetta, L1
Cecere, N; de Paola, I; DellaGreca, M; Longobardo, L1
Dekker, JM; Drevon, CA; Elshorbagy, AK; Nijpels, G; Nurk, E; Nygård, O; Refsum, H; Stehouwer, CD; Teerlink, T; Tell, GS; Ueland, PM; Vinknes, KJ; Vollset, SE1
Bártl, J; Chrastina, P; Hodík, J; Kožich, V; Krijt, J; Pešková, K1
Aliani, M; House, JD; Mayengbam, S; Raposo, S1
Hirschberger, LL; Jurkowska, H; Roman, HB; Stipanuk, MH1
Chi, YY; Coats, B; Gregory, JF; Midttun, Ø; Ralat, M; Rios-Avila, L; Stacpoole, PW; Ueland, PM1
Björkqvist, HG; Carlsson, GU; Gustavsson, BG; Kurlberg, GK; Odin, EA; Stoffregen, CC; Tångefjord, MT1
Faas, MM; Holwerda, KM; Lely, AT; Nolte, IM; Staff, AC; van Goor, H; Weedon-Fekjær, MS1
Balan, B; Beri, D; Chaubey, S; Subramaniam, S; Surendra, B; Tatu, U1
Makino, R; Okuyama, H; Tachibana, T; Tomonaga, S1
Huse, K; Olecka, M; Platzer, M1
Abdul Rehman, SA; Ali, MF; Devi, S; Gourinath, S; Tarique, KF1
Han, C; Liu, S; Liu, Y; Shi, L; Xiang, X1
Belardo, A; Gevi, F; Zolla, L1
Bakolitsa, C; Brenner, SE; Bromberg, Y; Cao, C; Capriotti, E; Casadio, R; De Baets, G; Dimster-Denk, DF; Friedberg, I; Giollo, M; Hu, Z; Karchin, R; Kasak, L; Katsonis, P; Leonardi, E; Lichtarge, O; Martelli, PL; Masica, D; Mooney, SD; Moult, J; Olatubosun, A; Pal, LR; Pandey, G; Radivojac, P; Repo, S; Rine, J; Rousseau, F; Savojardo, C; Schymkowitz, J; Thusberg, J; Tosatto, SCE; Väliaho, J; Van Durme, J; Vihinen, M; Yu, C1
Corrales, F; Franco, L; Guerrero, L; López-Rodas, G; Martí-Andrés, P; Paradela, A; Pérez, S; Rius-Pérez, S; Sastre, J; Taléns-Visconti, R; Torres, L; Torres-Cuevas, I1
Bai, L; Du, J; Huang, Y; Jin, H; Kong, W; Tang, C; Wang, X; Wang, Y; Zhang, D; Zhang, L1
Astegno, A; Conter, C; Dominici, P; Fernández-Rodríguez, C; Fruncillo, S; Martínez-Cruz, LA1
Danshiitsoodol, N; Ezumi, Y; Izuhara-Kihara, H; Kumagai, T; Matoba, Y; Noda, M; Oda, K; Sugiyama, M; Yasutake, C; Yoshida, T1
Chen, P; He, Q; Jiang, J; Liu, L; Shi, H; Song, Y; Tang, Y; Wang, B; Zhang, N; Zhou, H; Zhou, Z1
Bastani, NE; Dagnelie, PC; Elshorbagy, AK; Eussen, SJPM; Grootswagers, P; Kožich, V; Olsen, T; Refsum, H; Retterstøl, K; Stehouwer, CD; Stolt, ETK; Tore, EC; van Greevenbroek, MMJ; Vinknes, KJ1
Aghalarov, M; Aktuglu-Zeybek, C; Cansever, MS; Kıykım, E; Uygur, E; Zubarioglu, T1

Reviews

7 review(s) available for homocysteine and cystathionine

ArticleYear
Methylation & schizophrenia.
    The Alabama journal of medical sciences, 1975, Volume: 12, Issue:2

    Topics: Amines; Amino Acids; Animals; Behavior, Animal; Catecholamines; Cats; Cystathionine; Cysteine; Dihydroxyphenylalanine; Drug Tolerance; Hallucinogens; Homocysteine; Humans; Indoles; Methionine; Methylation; Mice; Schizophrenia; Serine; Taurine

1975
The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine.
    The American journal of clinical nutrition, 1992, Volume: 55, Issue:1

    Topics: Amino Acid Metabolism, Inborn Errors; Cystathionine; Homocysteine; Humans; Methionine; Methylation; S-Adenosylmethionine

1992
Methionine metabolism in mammals: the biochemical basis for homocystinuria.
    Metabolism: clinical and experimental, 1974, Volume: 23, Issue:4

    Topics: Alcohol Oxidoreductases; Cell-Free System; Cystathionine; Fibroblasts; Homocysteine; Homocystinuria; Humans; Hydro-Lyases; Liver; Methionine; Methylation; Methyltransferases; Protein Biosynthesis; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates

1974
Pathways and regulation of homocysteine metabolism in mammals.
    Seminars in thrombosis and hemostasis, 2000, Volume: 26, Issue:3

    Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Heme; Homocysteine; Isoenzymes; Kinetics; Mammals; Methionine; Methionine Adenosyltransferase; Organ Specificity; Oxidation-Reduction; Pyridoxal Phosphate; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tetrahydrofolates

2000
The enzymology of cystathionine biosynthesis: strategies for the control of substrate and reaction specificity.
    Archives of biochemistry and biophysics, 2005, Jan-01, Volume: 433, Issue:1

    Topics: Allosteric Regulation; Amino Acid Substitution; Binding Sites; Carbon-Oxygen Lyases; Catalysis; Catalytic Domain; Cystathionine; Cystathionine beta-Synthase; Dimerization; Enzyme Activation; Gene Expression Regulation, Enzymologic; Homocysteine; Kinetics; Oxidation-Reduction; Protein Structure, Tertiary; Pyridoxal Phosphate; Stereoisomerism; Substrate Specificity

2005
Toxicity of methionine in humans.
    The Journal of nutrition, 2006, Volume: 136, Issue:6 Suppl

    Topics: Cystathionine; Diet; Endothelium, Vascular; Homocysteine; Humans; Infant; Infant Nutritional Physiological Phenomena; Methionine; Nutritional Physiological Phenomena; Nutritional Requirements

2006
Homocysteine, iron and cardiovascular disease: a hypothesis.
    Nutrients, 2015, Feb-06, Volume: 7, Issue:2

    Topics: Biomarkers; Cardiovascular Diseases; Cystathionine; Dietary Supplements; Folic Acid; Free Radicals; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Lipoproteins, LDL; Methionine; Risk Factors; S-Adenosylhomocysteine; Vitamin B Complex

2015

Trials

14 trial(s) available for homocysteine and cystathionine

ArticleYear
Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations.
    Lancet (London, England), 1995, Jul-08, Volume: 346, Issue:8967

    Topics: Aged; Aged, 80 and over; Avitaminosis; Citrates; Cystathionine; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Injections, Intramuscular; Male; Methylmalonic Acid; Placebos; Prospective Studies; Pyridoxine; Vitamin B 12; Vitamin B 12 Deficiency

1995
Total homocysteine is associated with nephropathy in non-insulin-dependent diabetes mellitus.
    Metabolism: clinical and experimental, 1999, Volume: 48, Issue:9

    Topics: Adult; Aged; Albuminuria; Cystathionine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Kidney Function Tests; Male; Methylmalonic Acid; Middle Aged; Regression Analysis; Vitamins

1999
Is the increase in serum cystathionine levels in patients with liver cirrhosis a consequence of impaired homocysteine transsulfuration at the level of gamma-cystathionase?
    Scandinavian journal of gastroenterology, 2000, Volume: 35, Issue:8

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Biomarkers; Chromatography, Gas; Cystathionine; Cystathionine gamma-Lyase; Female; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Liver Cirrhosis; Male; Middle Aged; Probability; Reference Values; Sensitivity and Specificity; Severity of Illness Index; Statistics, Nonparametric

2000
Measurement of intracellular sulfur amino acid metabolism in humans.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 280, Issue:6

    Topics: Adult; Carbon Isotopes; Cystathionine; Energy Metabolism; Female; Homocysteine; Humans; Male; Methionine; Tritium

2001
Investigation of relationship between reduced, oxidized, and protein-bound homocysteine and vascular endothelial function in healthy human subjects.
    Circulation research, 2001, Jul-20, Volume: 89, Issue:2

    Topics: Administration, Oral; Adult; Brachial Artery; Cystathionine; Cysteine; Endothelium, Vascular; Female; Homocysteine; Humans; Male; Methionine; Oxidation-Reduction; Proteins; Time Factors; Vasodilation

2001
Homocysteine levels in patients treated with lipid apheresis: effect of a vitamin therapy.
    European journal of clinical investigation, 2001, Volume: 31, Issue:8

    Topics: Adult; Cystathionine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipoproteinemia Type II; Lipids; Male; Vitamin B 12; Vitamin B 6

2001
Decrease of elevated N,N-dimethylglycine and N-methylglycine in human immunodeficiency virus infection during short-term highly active antiretroviral therapy.
    Metabolism: clinical and experimental, 2001, Volume: 50, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Antigens, CD; Antiretroviral Therapy, Highly Active; Biomarkers; Cystathionine; Cysteine; Fasting; Female; Folic Acid; HIV Infections; HIV-1; Homocysteine; Humans; Male; Methionine; Methylmalonic Acid; Middle Aged; Multivariate Analysis; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Sarcosine; Vitamin B 6

2001
Variation in plasma cystathionine and its relation to changes in plasma concentrations of homocysteine and methionine in healthy subjects during a 24-h observation period.
    The American journal of clinical nutrition, 2004, Volume: 79, Issue:1

    Topics: Adult; Circadian Rhythm; Cystathionine; Fasting; Female; Food; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Methionine

2004
Influence of hemodialysis membrane permeability on serum levels of advanced glycation end products (AGEs) and homocysteine metabolites.
    Clinical nephrology, 2004, Volume: 61, Issue:3

    Topics: Arginine; Cross-Over Studies; Cystathionine; Enzyme-Linked Immunosorbent Assay; Female; Fluorescence; Glycation End Products, Advanced; Homocysteine; Humans; Kidneys, Artificial; Lysine; Male; Membranes, Artificial; Middle Aged; Polymers; Prospective Studies; Renal Dialysis; Sarcosine; Sulfones

2004
Changes in basal and postmethionine load concentrations of total homocysteine and cystathionine after B vitamin intervention.
    The American journal of clinical nutrition, 2004, Volume: 80, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analysis of Variance; Cardiovascular Diseases; Cystathionine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Norway; Prospective Studies; Vitamin B 12; Vitamin B 6

2004
Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:3

    Topics: Acetylcysteine; Adult; Arginine; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Cystathionine; Cysteine; Dipeptides; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Male; Methionine; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vasodilation

2005
Iron-dependent formation of homocysteine from methionine and other thioethers.
    European journal of clinical nutrition, 2007, Volume: 61, Issue:12

    Topics: Adult; Area Under Curve; Cross-Over Studies; Cystathionine; Female; Homocysteine; Humans; Hydrogen-Ion Concentration; Iron; Iron Chelating Agents; Male; Methionine; S-Adenosylhomocysteine

2007
Simultaneous determination of cystathionine, total homocysteine, and methionine in dried blood spots by liquid chromatography/tandem mass spectrometry and its utility for the management of patients with homocystinuria.
    Clinica chimica acta; international journal of clinical chemistry, 2014, Nov-01, Volume: 437

    Topics: Adolescent; Child; Child, Preschool; Chromatography, Liquid; Cystathionine; Disease Management; Dried Blood Spot Testing; Female; Homocysteine; Homocystinuria; Humans; Infant; Infant, Newborn; Male; Methionine; Tandem Mass Spectrometry

2014
Reduced folate and serum vitamin metabolites in patients with rectal carcinoma: an open-label feasibility study of pemetrexed with folic acid and vitamin B12 supplementation.
    Anti-cancer drugs, 2016, Volume: 27, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cystathionine; Feasibility Studies; Female; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Intestinal Mucosa; Male; Methylmalonic Acid; Middle Aged; Neoadjuvant Therapy; Pemetrexed; Rectal Neoplasms; Rectum; Vitamin B 12

2016

Other Studies

122 other study(ies) available for homocysteine and cystathionine

ArticleYear
Methionine metabolism and vitamin B6 status in women using oral contraceptives.
    The American journal of clinical nutrition, 1978, Volume: 31, Issue:4

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Contraceptives, Oral; Contraceptives, Oral, Combined; Cystathionine; Female; Homocysteine; Humans; Methionine; Pyridoxine; Taurine

1978
Biosynthesis and metabolism of cystathionine in Astragalus pectinatus.
    Biochimica et biophysica acta, 1977, Feb-28, Volume: 496, Issue:2

    Topics: Cystathionine; Cysteine; Homocysteine; Methionine; Plants; Sulfur

1977
Enzymatic lesions in methionine mutants of Aspergillus nidulans: role and regulation of an alternative pathway for cysteine and methionine synthesis.
    Journal of bacteriology, 1975, Volume: 124, Issue:2

    Topics: Aspergillus nidulans; Cystathionine; Cysteine; Genes, Regulator; Glutathione; Homocysteine; Lyases; Methionine; Mutation; Suppression, Genetic; Taurine

1975
Effects of glutamate and sulphur containing amino acids on ammonia toxicity and methionine sulphoximine convulsions in mice.
    Brain research, 1976, Jun-18, Volume: 109, Issue:3

    Topics: Amino Acids, Sulfur; Animals; Anticonvulsants; Arginine; Cystathionine; Cysteic Acid; Glutamates; Homocysteine; Male; Methionine; Methionine Sulfoximine; Mice; Quaternary Ammonium Compounds; Seizures; Taurine

1976
The simultaneous determination of oxidized and reduced glutathiones in liver tissue by ion pairing reverse phase high performance liquid chromatography with a coulometric electrochemical detector.
    Clinica chimica acta; international journal of clinical chemistry, 1989, Apr-14, Volume: 180, Issue:3

    Topics: Animals; Bile; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Electrochemistry; Glutathione; Homocysteine; Liver; Male; Methionine; Oxidation-Reduction; Rats

1989
[Effects of gene localization and its metabolic significance in trisomy 21].
    Bulletin de l'Academie nationale de medecine, 1985, Volume: 169, Issue:9

    Topics: Chromosome Mapping; Chromosomes, Human, 21-22 and Y; Cystathionine; Cystathionine beta-Synthase; Down Syndrome; Fibroblasts; Homocysteine; Homocystinuria; Humans; Methionine

1985
Methionine metabolism in mammals. The methionine-sparing effect of cystine.
    The Journal of biological chemistry, 1988, Aug-25, Volume: 263, Issue:24

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine; Cystathionine beta-Synthase; Cystine; Diet; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylmethionine

1988
Methionine metabolism in isolated perfused livers from rats fed on zinc-deficient and restricted diets.
    The British journal of nutrition, 1986, Volume: 56, Issue:2

    Topics: Animals; Butyrates; Cystathionine; Diet; Homocysteine; In Vitro Techniques; Liver; Male; Methionine; Perfusion; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Zinc

1986
Glutathione changes occurring after S-adenosylhomocysteine hydrolase inhibition.
    Archives of biochemistry and biophysics, 1985, Aug-01, Volume: 240, Issue:2

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Antigens, Neoplasm; Cells, Cultured; Cystathionine; Glutathione; Homocysteine; Hydrolases; Leukemia L5178; Liver; Male; Methionine; Oxidation-Reduction; Rats; Rats, Inbred Strains; Time Factors

1985
Redistribution of pyridoxal phosphate in the male rat liver as a result of repeated injections of hydrocortisone.
    Biochimica et biophysica acta, 1973, Jan-24, Volume: 297, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartic Acid; Carboxy-Lyases; Cystathionine; Cysteine; Dose-Response Relationship, Drug; Homocysteine; Homoserine; Hydro-Lyases; Hydrocortisone; L-Serine Dehydratase; Liver; Lyases; Male; Pyridoxal Phosphate; Rats; Seasons; Serine; Time Factors; Tyrosine Transaminase

1973
Cystationine synthesis in yeast: an alternative pathway for homocysteine biosynthesis.
    Journal of bacteriology, 1972, Volume: 112, Issue:1

    Topics: Acetates; Catalysis; Cell-Free System; Cystathionine; Cysteine; Homocysteine; Homoserine; Hydro-Lyases; L-Serine Dehydratase; Lyases; Neurospora crassa; Saccharomyces; Saccharomyces cerevisiae; Salmonella typhimurium; Sulfides; Sulfur Isotopes; Yeasts

1972
A study of the behavioral disruption of mice induced by l-methionine and related compounds.
    Psychopharmacologia, 1974, Apr-08, Volume: 36, Issue:2

    Topics: Amphetamine; Animals; Behavior, Animal; Betaine; Chlorpromazine; Cystathionine; Folic Acid; Histidine; Homocysteine; Homoserine; Male; Mescaline; Methionine; Mice; N,N-Dimethyltryptamine; Niacinamide; Serine; Social Behavior

1974
Mutant human fibroblast clones able to grow on homocysteine instead of cyst(e)ine.
    Experimental cell research, 1971, Volume: 69, Issue:2

    Topics: Alkanesulfonates; Cell Line; Clone Cells; Colorimetry; Culture Media; Cystathionine; Cystine; Diploidy; Fibroblasts; Homocysteine; Humans; Karyotyping; Lyases; Mutagens; Mutation; Nitrosoguanidines; Skin; Stereoisomerism

1971
Methionine metabolism in mammals: regulatory effects of S-adenosylhomocysteine.
    Archives of biochemistry and biophysics, 1974, Volume: 165, Issue:2

    Topics: Adenosine; Animals; Betaine; Chromatography, Gel; Cystathionine; Enzyme Activation; Homocysteine; Kinetics; Liver; Lyases; Methionine; Methyltransferases; Rats; Regression Analysis

1974
Ethanol-induced changes in methionine metabolism in rat liver.
    Biochemical and biophysical research communications, 1974, Nov-27, Volume: 61, Issue:2

    Topics: Animals; Cystathionine; Dietary Proteins; Ethanol; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; S-Adenosylmethionine

1974
[Influence of cysteine or of its sulfur-containing precursors on the development of adult human liver diploid cell lines and of heteroploid lines derived from the transformation of the latter].
    Pathologie-biologie, 1972, Volume: 20, Issue:3

    Topics: Aneuploidy; Cell Division; Cell Line; Cells, Cultured; Culture Media; Cystathionine; Cysteine; Diploidy; Homocysteine; Humans; Liver; Methionine; Transformation, Genetic

1972
Factors affecting virulence of Shigella flexneri: defective methionine synthesis in an Escherichia coli-Shigella hybrid.
    Journal of bacteriology, 1972, Volume: 112, Issue:1

    Topics: Animals; Cell Survival; Cystathionine; Cysteine; Escherichia coli; Genes; Genetics, Microbial; Guinea Pigs; Homocysteine; Homoserine; Hybridization, Genetic; Methionine; RNA, Bacterial; Shigella; Shigella flexneri; Species Specificity; Temperature; Transduction, Genetic; Virulence

1972
An Aspergillus nidulans mutant lacking cystathionine -synthase: identity of L-serine sulfhydrylase with cystathionine -synthase and its distinctness from O-acetyl-L-serine sulfhydrylase.
    Biochimica et biophysica acta, 1973, Jan-24, Volume: 297, Issue:1

    Topics: Aspergillus; Aspergillus nidulans; Carbon Isotopes; Cell-Free System; Culture Media; Cystathionine; Cysteine; Homocysteine; Hydro-Lyases; Molecular Weight; Mutation; Selenium; Serine; Species Specificity

1973
Studies on beta-cystathionase and omicron-acetylhomoserine sulfhydrylase as the enzymes of alternative methionine biosynthetic pathways in Aspergillus nidulans.
    Acta biochimica Polonica, 1973, Volume: 20, Issue:2

    Topics: Acetylation; Aspergillus; Aspergillus nidulans; Cystathionine; Enzyme Repression; Homocysteine; Homoserine; Hydrogen Sulfide; Lyases; Methionine; Serine

1973
The cysteine desulfhydrase of Salmonella typhimurium. Kinetic and catalytic properties.
    The Journal of biological chemistry, 1973, Sep-10, Volume: 248, Issue:17

    Topics: Binding Sites; Cell-Free System; Centrifugation, Density Gradient; Chromatography, Gel; Cystathionine; Cysteine; Drug Stability; Enzyme Activation; Enzyme Induction; Homocysteine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Lyases; Mathematics; Mercaptoethanol; Methionine; Mutation; Salmonella typhimurium; Serine; Stereoisomerism; Structure-Activity Relationship; Sulfhydryl Compounds

1973
Effect of methionine and vitamin B-12 on the activities of methionine biosynthetic enzymes in metJ mutants of Escherichia coli K12.
    Archives of biochemistry and biophysics, 1973, Volume: 158, Issue:1

    Topics: Adenosine Triphosphate; Culture Media; Cystathionine; Enzyme Repression; Escherichia coli; Folic Acid; Homocysteine; Hydro-Lyases; L-Serine Dehydratase; Methionine; Methyltransferases; Mutation; Oxidoreductases; S-Adenosylmethionine; Time Factors; Transferases; Vitamin B 12

1973
Hereditary transcobalamin II deficiency: the role of transcobalamin II in vitamin B 12 -mediated reactions.
    The Journal of pediatrics, 1972, Volume: 81, Issue:6

    Topics: Amino Acid Metabolism, Inborn Errors; Cystathionine; DNA; Hematopoietic System; Homocysteine; Humans; Infant; Infant, Newborn; Isomerases; Leukocytes; Malonates; Methionine; Methyltransferases; Oxidation-Reduction; Propionates; Succinates; Vitamin B 12; Vitamin B 12 Deficiency

1972
[Cystathionuria and defective enzyme regulation].
    Clinica chimica acta; international journal of clinical chemistry, 1973, Jan-24, Volume: 43, Issue:2

    Topics: Administration, Oral; Amino Acid Metabolism, Inborn Errors; Child; Chromatography, Ion Exchange; Chromatography, Paper; Cystathionine; Cysteine; Electrophoresis, Paper; Female; Homocysteine; Homocystine; Homoserine; Humans; Hydro-Lyases; Hydrocortisone; Liver; Lyases; Methionine; Pyridoxine; Sulfur

1973
[Role of sulfated amino acids in the growth of Corynebacterium sepedonicum (Spieck, et Kott) Skapt. et Burkh].
    Canadian journal of microbiology, 1973, Volume: 19, Issue:3

    Topics: Amino Acids; Chromatography, Paper; Colorimetry; Corynebacterium; Culture Media; Cystathionine; Glutathione; Homocysteine; Homocystine; Methionine; S-Adenosylmethionine; Stereoisomerism; Sulfur

1973
Kinetic characteristics of cisteine desulphydrase in the liver and pancreas of different biological species.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1973, May-15, Volume: 45, Issue:1

    Topics: Animals; Chickens; Cystathionine; Cysteine; Dogs; Fishes; Homocysteine; In Vitro Techniques; Kinetics; Liver; Lyases; Mice; Pancreas; Pyridoxal Phosphate; Pyruvates; Rats; Species Specificity; Swine

1973
[Chiro-optical properties of sulfur containing amino acids].
    European journal of biochemistry, 1973, Jun-15, Volume: 35, Issue:3

    Topics: Alanine; Amino Acids; Circular Dichroism; Cystathionine; Cysteine; Cystine; Homocysteine; Homocystine; Hydrogen-Ion Concentration; Methionine; Molecular Conformation; Optical Rotatory Dispersion; Spectrophotometry, Ultraviolet; Sulfides; Sulfur; Temperature

1973
Interaction of pyridoxal phosphate analogues with apoenzymes of gamma-cystathionase and serine sulphhydrase.
    Biochemical and biophysical research communications, 1973, Dec-10, Volume: 55, Issue:3

    Topics: Animals; Apoproteins; Binding Sites; Borohydrides; Chickens; Circular Dichroism; Cystathionine; Homocysteine; Hydro-Lyases; Hydrogen Sulfide; Kinetics; Liver; Lyases; Methylation; Penicillamine; Protein Binding; Pyridoxal Phosphate; Rats; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1973
Homocystinuria due to cystathionine synthase deficiency: enzymatic and ultrastructural studies.
    The Journal of pediatrics, 1974, Volume: 84, Issue:3

    Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Biopsy, Needle; Child; Child, Preschool; Cystathionine; Female; Heterozygote; Homocysteine; Homocystinuria; Humans; Hydro-Lyases; Liver; Male; Methionine; Mitochondria, Liver; Pyridoxine; Transferases; Transketolase

1974
Cystathionine gamma-synthesis from homocysteine and cysteine by mammalian tissue.
    Biochemical medicine, 1974, Volume: 9, Issue:1

    Topics: Animals; Brain; Chromatography, Ion Exchange; Cystathionine; Cysteine; Cystine; Homocysteine; Humans; Kidney; Liver; Lyases; Male; Mice; Organ Specificity; Precipitin Tests; Rabbits; Rats; Species Specificity; Subcellular Fractions; Sulfur Radioisotopes

1974
Effect of pyridoxine treatment of a cystathioninuric patient on the urinary excretion of some unusual sulfur-containing amino acids.
    Clinica chimica acta; international journal of clinical chemistry, 1974, Feb-28, Volume: 51, Issue:1

    Topics: Acetamides; Amino Acid Metabolism, Inborn Errors; Amino Acids, Sulfur; Autoanalysis; Chromatography, Ion Exchange; Cystathionine; Cysteine; Electrophoresis, Paper; Female; Homocysteine; Homocystine; Humans; Pyridoxine; Time Factors

1974
Nutrition and metabolism of sulphur amino acids in Argyrotaenia velutinana larvae.
    Journal of insect physiology, 1972, Volume: 18, Issue:1

    Topics: Animals; Cystathionine; Cysteine; Female; Germ-Free Life; Homocysteine; Insecta; Larva; Male; Metamorphosis, Biological; Methionine; Pupa

1972
[Active center of rat liver homoserine dehydratase].
    Biochimica et biophysica acta, 1972, Feb-28, Volume: 258, Issue:2

    Topics: Alanine; Animals; Binding Sites; Cystathionine; Cysteine; Deamination; Homocysteine; Homoserine; Hydro-Lyases; Hydrogen Sulfide; Kinetics; Liver; Methionine; Protein Binding; Rats; Stereoisomerism; Structure-Activity Relationship; Sulfhydryl Compounds

1972
Homocysteinemia and arteriosclerosis.
    American heart journal, 1972, Volume: 83, Issue:4

    Topics: Amino Acid Metabolism, Inborn Errors; Arteriosclerosis; Cystathionine; Homocysteine

1972
The formation of sulphur-containing amino acids in germinating seeds of rape (Brassica napus L.).
    The Biochemical journal, 1972, Volume: 126, Issue:4

    Topics: Amino Acids; Carbon Isotopes; Cystathionine; Cysteine; Homocysteine; Homoserine; Methionine; Seeds; Sulfides; Sulfur Isotopes

1972
Hyperaminoacidemia in rabbits treated with 6-azauridine triacetate.
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1971, Nov-22, Volume: 10, Issue:22

    Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Antimetabolites; Cystathionine; Cysteine; Homocysteine; Male; Methionine; Nucleosides; Rabbits

1971
Differential cyst(e)ine requirements in human T and B lymphoblastoid cell lines.
    International archives of allergy and applied immunology, 1982, Volume: 68, Issue:1

    Topics: B-Lymphocytes; Cell Line; Concanavalin A; Cystathionine; Cysteine; Cystine; Herpesvirus 4, Human; Homocysteine; Humans; Lymphocyte Activation; Staphylococcal Protein A; T-Lymphocytes

1982
The effects of chronic isoniazid intoxication on motor end plate sprouting in rat sternocostalis muscle and on responses to partial denervation and local botulinum toxin.
    Acta neuropathologica, 1984, Volume: 63, Issue:2

    Topics: Animals; Botulinum Toxins; Cystathionine; Cysteine; Cystine; Drug Interactions; Female; Glutathione; Homocysteine; Isoniazid; Motor Endplate; Neuromuscular Junction; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains

1984
Direct homocysteine biosynthesis from O-succinylhomoserine in Escherichia coli: an alternate pathway that bypasses cystathionine.
    Journal of bacteriology, 1983, Volume: 153, Issue:1

    Topics: Carbon-Oxygen Lyases; Cystathionine; Cystathionine gamma-Lyase; Escherichia coli; Homocysteine; Homoserine; Lyases; Mutation

1983
Cloning, purification, and characterization of beta-cystathionase from Escherichia coli.
    Biochemistry, 1982, Jun-22, Volume: 21, Issue:13

    Topics: Amino Acids; Cloning, Molecular; Cystathionine; Escherichia coli; Homocysteine; Kinetics; Lyases; Molecular Weight; Plasmids; Pyridoxal Phosphate

1982
Cysteine and homocysteine synthesis in Saccharomycopsis lipolytica; identification and characterization of two cysteine synthases.
    Acta biochimica Polonica, 1982, Volume: 29, Issue:1-2

    Topics: Ascomycota; Carbon-Oxygen Lyases; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Cysteine Synthase; Homocysteine; Lyases; Multienzyme Complexes; Mutation; Pyridoxal Phosphate; Saccharomyces cerevisiae Proteins; Saccharomycopsis; Substrate Specificity

1982
Effect of 1-aminoproline on methionine metabolism in rats.
    Archives of biochemistry and biophysics, 1981, Volume: 206, Issue:2

    Topics: Animals; Cystathionine; Homocysteine; Male; Methionine; Proline; Rats; Stereoisomerism; Sulfoxides

1981
Involvement of the cystathionine pathway in the biosynthesis of glutathione by isolated rat hepatocytes.
    Archives of biochemistry and biophysics, 1980, Oct-01, Volume: 204, Issue:1

    Topics: Alkynes; Animals; Cystathionine; Cystathionine gamma-Lyase; Glutathione; Glycine; Homocysteine; In Vitro Techniques; Kinetics; Liver; Male; Methionine; Rats

1980
Carbon tetrachloride-induced hepatic injury is associated with global DNA hypomethylation and homocysteinemia: effect of S-adenosylmethionine treatment.
    Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:4 Pt 1

    Topics: Animals; Carbon Tetrachloride; Cystathionine; DNA; Folic Acid; Homocysteine; Liver; Liver Cirrhosis, Experimental; Male; Methionine; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine

1995
Evidence that homocysteine is an independent risk factor for atherosclerosis in hyperlipidemic patients.
    The American journal of cardiology, 1995, Jan-15, Volume: 75, Issue:2

    Topics: Aged; Analysis of Variance; Arteriosclerosis; Coronary Disease; Cystathionine; Folic Acid; Homocysteine; Humans; Hyperlipidemias; Methylmalonic Acid; Middle Aged; Pyridoxine; Risk Factors

1995
Methionine biosynthesis in higher plants. I. Purification and characterization of cystathionine gamma-synthase from spinach chloroplasts.
    Archives of biochemistry and biophysics, 1995, Jan-10, Volume: 316, Issue:1

    Topics: Alkynes; Carbon-Oxygen Lyases; Carbon-Sulfur Lyases; Cell Compartmentation; Chloroplasts; Cystathionine; Glycine; Homocysteine; Homoserine; Kinetics; Lyases; Methionine; Molecular Weight; Pargyline; Plant Leaves; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry; Spinacia oleracea

1995
Methionine biosynthesis in higher plants. II. Purification and characterization of cystathionine beta-lyase from spinach chloroplasts.
    Archives of biochemistry and biophysics, 1995, Jan-10, Volume: 316, Issue:1

    Topics: Aminobutyrates; Cell Compartmentation; Chloroplasts; Cystathionine; Homocysteine; Kinetics; Lyases; Methionine; Plant Leaves; Pyridoxal Phosphate; Pyruvates; Pyruvic Acid; Spectrophotometry; Spinacia oleracea

1995
Transsulfuration depends on heme in addition to pyridoxal 5'-phosphate. Cystathionine beta-synthase is a heme protein.
    The Journal of biological chemistry, 1994, Oct-14, Volume: 269, Issue:41

    Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Escherichia coli; Heme; Hemeproteins; Homocysteine; Humans; Kinetics; Liver; Pyridoxal Phosphate; Rats; Recombinant Proteins; Serine; Spectrophotometry; Sulfur

1994
Identification of new cystathionine mono-oxo acids, S-(3-oxo-3-carboxy-n-propyl) cysteine and S-(2-oxo-2-carboxyethyl) homocysteine, in the urine of a patient with cystathioninuria.
    Archives of biochemistry and biophysics, 1993, Volume: 305, Issue:2

    Topics: Amino Acid Metabolism, Inborn Errors; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Keto Acids

1993
Liver DNA and RNA metabolism in rats fed diets lacking methionine plus cysteine with or without restricted energy.
    Revista espanola de fisiologia, 1995, Volume: 51, Issue:3

    Topics: Animal Feed; Animals; Body Weight; Cell Nucleus; Cell Size; Cystathionine; Cysteine; Deoxyribonucleases; Diet; DNA; Eating; Energy Metabolism; Homocysteine; Liver; Male; Methionine; Methylation; Organ Size; Proteins; Rats; Rats, Wistar; Ribonucleases; RNA; Solubility

1995
The effect of a subnormal vitamin B-6 status on homocysteine metabolism.
    The Journal of clinical investigation, 1996, Jul-01, Volume: 98, Issue:1

    Topics: Administration, Oral; Adult; Asthma; Bronchodilator Agents; Cystathionine; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Pyridoxine; Theophylline; Vitamin B 6 Deficiency

1996
Enhanced levels of biochemical markers for cobalamin deficiency in totally gastrectomized rats: uncoupling of the enhancement from the severity of spongy vacuolation in spinal cord.
    Experimental neurology, 1997, Volume: 144, Issue:2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Pernicious; Animals; Bacteria, Anaerobic; Citrates; Cystathionine; Disease Models, Animal; Erythromycin; Gastrectomy; Homocysteine; Humans; Intestines; Lincomycin; Male; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Postgastrectomy Syndromes; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Diseases; Vacuoles; Vitamin B 12; Vitamin B 12 Deficiency

1997
Increased concentrations of homocysteine in the cerebrospinal fluid in patients with fibromyalgia and chronic fatigue syndrome.
    Scandinavian journal of rheumatology, 1997, Volume: 26, Issue:4

    Topics: Adult; Cystathionine; Fatigue Syndrome, Chronic; Female; Fibromyalgia; Homocysteine; Humans; Methionine; Middle Aged; Models, Biological; Vitamin B 12

1997
Cellular mechanisms of resistance to chronic oxidative stress.
    Free radical biology & medicine, 1998, Volume: 24, Issue:9

    Topics: Animals; Antioxidants; bcl-2-Associated X Protein; Biological Transport; Catalase; Cell Line; Cell Survival; Cystathionine; Cystine; Drug Resistance; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Heat-Shock Proteins; Homocysteine; Mice; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Oxidative Stress; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Time Factors; Up-Regulation

1998
Evidence of altered homocysteine metabolism in chronic renal failure.
    Nephron, 1999, Volume: 83, Issue:4

    Topics: Arteriosclerosis; Citrates; Creatinine; Cystathionine; Cysteine; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methionine; Methylmalonic Acid; Middle Aged; Renal Dialysis; Risk Factors; Vitamins

1999
The quantitatively important relationship between homocysteine metabolism and glutathione synthesis by the transsulfuration pathway and its regulation by redox changes.
    Biochemistry, 2000, Oct-24, Volume: 39, Issue:42

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cystathionine; Cystathionine beta-Synthase; Glutathione; Hepatocytes; Homocysteine; Humans; Intracellular Fluid; Oxidation-Reduction; Oxidative Stress; Sulfur; tert-Butylhydroperoxide; Tumor Cells, Cultured

2000
Role of homocysteine, cystathionine and methylmalonic acid measurement for diagnosis of vitamin deficiency in high-aged subjects.
    European journal of clinical investigation, 2000, Volume: 30, Issue:12

    Topics: Adult; Aged; Cystathionine; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Kidney; Male; Methylmalonic Acid; Middle Aged; Models, Chemical; Pyridoxine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency

2000
Occurrence of transsulfuration in synthesis of L-homocysteine in an extremely thermophilic bacterium, Thermus thermophilus HB8.
    Journal of bacteriology, 2001, Volume: 183, Issue:6

    Topics: Culture Media; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Cysteine Synthase; Gene Expression Regulation, Bacterial; Homocysteine; Lyases; Methionine; S-Adenosylmethionine; Sulfur; Temperature; Thermus thermophilus

2001
Disposition of homocysteine in subjects heterozygous for homocystinuria due to cystathionine beta-synthase deficiency: relationship between genotype and phenotype.
    American journal of medical genetics, 2001, May-01, Volume: 100, Issue:3

    Topics: Adolescent; Adult; Aged; Cystathionine; Cystathionine beta-Synthase; DNA; Female; Genotype; Heterozygote; Homocysteine; Homocystinuria; Humans; Male; Methionine; Middle Aged; Mutation; Phenotype; Reference Values

2001
Homocysteine metabolism in children with Down syndrome: in vitro modulation.
    American journal of human genetics, 2001, Volume: 69, Issue:1

    Topics: Adenosine; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cystathionine beta-Synthase; Cysteine; DNA Methylation; Down Syndrome; Glutathione; Homocysteine; Humans; Leucovorin; Lymphocytes; Methionine; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Superoxide Dismutase; Thymidine; Vitamin B 12

2001
Biosynthesis of methionine from homocysteine, cystathionine and homoserine plus cysteine by mixed rumen microorganisms in vitro.
    Applied microbiology and biotechnology, 2001, Volume: 55, Issue:6

    Topics: Amino Acids; Aminobutyrates; Anaerobiosis; Animals; Bacteria; Culture Media; Cystathionine; Cysteine; Eukaryota; Goats; Homocysteine; Homoserine; Methionine; Rumen; Temperature

2001
The reaction of yeast cystathionine beta-synthase is rate-limited by the conversion of aminoacrylate to cystathionine.
    Biochemistry, 2001, Sep-11, Volume: 40, Issue:36

    Topics: Cystathionine; Cystathionine beta-Synthase; Feedback; Homocysteine; Kinetics; Models, Chemical; Saccharomyces cerevisiae; Serine; Spectrophotometry

2001
Genetic defects as important factors for moderate hyperhomocysteinemia.
    Clinical chemistry and laboratory medicine, 2001, Volume: 39, Issue:8

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Age Factors; Aged; Aged, 80 and over; Cystathionine; DNA Mutational Analysis; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Protein Binding; Risk Factors; Sex Factors; Vitamin B 12; Vitamin B 6

2001
Homocysteine, cystathionine, methylmalonic acid and B-vitamins in patients with renal disease.
    Clinical chemistry and laboratory medicine, 2001, Volume: 39, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Cystathionine; Female; Homocysteine; Humans; Immunoassay; Kidney Diseases; Kidney Transplantation; Male; Methylmalonic Acid; Middle Aged; Renal Dialysis; Vitamin B Complex

2001
Does a single vitamin B-supplementation induce functional vitamin B-deficiency?
    Clinical chemistry and laboratory medicine, 2001, Volume: 39, Issue:8

    Topics: Adult; Cystathionine; Cysteine; Dietary Supplements; Folic Acid; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Methionine; Methylmalonic Acid; Middle Aged; Models, Biological; Pilot Projects; Time Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency

2001
Metabolism of amino acids in cats with severe cobalamin deficiency.
    American journal of veterinary research, 2001, Volume: 62, Issue:12

    Topics: Amino Acids; Animals; Cat Diseases; Cats; Cystathionine; Cysteine; Female; Gastrointestinal Diseases; Homocysteine; Immunoassay; Male; Methionine; Methylmalonic Acid; Statistics, Nonparametric; Vitamin B 12; Vitamin B 12 Deficiency

2001
Yeast cystathionine beta-synthase reacts with L-allothreonine, a non-natural substrate, and L-homocysteine to form a new amino acid, 3-methyl-L-cystathionine.
    Biochemistry, 2002, Feb-12, Volume: 41, Issue:6

    Topics: Circular Dichroism; Cystathionine; Cystathionine beta-Synthase; Homocysteine; Kinetics; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Saccharomyces cerevisiae; Serine; Spectrophotometry; Substrate Specificity; Threonine

2002
Stopped-flow kinetic analysis of the reaction catalyzed by the full-length yeast cystathionine beta-synthase.
    The Journal of biological chemistry, 2002, Jun-21, Volume: 277, Issue:25

    Topics: Catalysis; Cystathionine; Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Heme; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae; Serine; Spectrophotometry; Time Factors

2002
Elevated plasma total homocysteine in severe methionine adenosyltransferase I/III deficiency.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:8

    Topics: Adolescent; Child; Child, Preschool; Cystathionine; Cystathionine beta-Synthase; Female; Homocysteine; Humans; Infant; Isoenzymes; Lyases; Male; Methionine; Methionine Adenosyltransferase

2002
Synthesis of optically active homocysteine from methionine and its use in preparing four stereoisomers of cystathionine.
    Chemical & pharmaceutical bulletin, 2002, Volume: 50, Issue:8

    Topics: Cystathionine; Homocysteine; Methionine; Optical Rotation; Stereoisomerism

2002
Molecular characterization of a cystathionine beta-synthase gene, CBS1, in Magnaporthe grisea.
    Eukaryotic cell, 2002, Volume: 1, Issue:2

    Topics: Amino Acid Sequence; Cystathionine; Cystathionine beta-Synthase; Genes, Fungal; Homocysteine; Magnaporthe; Mitochondrial Proteins; Molecular Sequence Data; Plant Diseases; Saccharomyces cerevisiae Proteins; Sequence Alignment; Sequence Analysis, Protein; Trans-Activators; Vitamin B 12

2002
Kinetics of the yeast cystathionine beta-synthase forward and reverse reactions: continuous assays and the equilibrium constant for the reaction.
    Biochemistry, 2003, Jan-21, Volume: 42, Issue:2

    Topics: Catalysis; Cystathionine; Cystathionine beta-Synthase; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Recombinant Proteins; Saccharomyces cerevisiae Proteins; Sequence Deletion; Serine; Spectrophotometry; Substrate Specificity

2003
Serum levels of total homocysteine, homocysteine metabolites and of advanced glycation end-products (AGEs) in patients after renal transplantation.
    Clinical nephrology, 2003, Volume: 59, Issue:2

    Topics: Adult; Arginine; Coronary Disease; Cystathionine; Female; Glycation End Products, Advanced; Homocysteine; Humans; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Kidney Transplantation; Logistic Models; Lysine; Male; Methylmalonic Acid; Middle Aged; Risk Factors

2003
Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
    Journal of bacteriology, 2003, Volume: 185, Issue:7

    Topics: Amino Acid Sequence; Archaeal Proteins; Binding Sites; Cystathionine; Cysteine; Cysteine Synthase; Desulfurococcaceae; Dithiothreitol; Enzyme Activation; Enzyme Stability; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Sequence Homology, Amino Acid; Serine; Substrate Specificity; Sulfides; Temperature

2003
[Cysteine, homocysteine, cystathionine & cysteinamine as necrotropic liver protective substances, combined with glucose & fructose].
    Die Medizinische, 1957, Apr-27, Issue:17

    Topics: Catabolite Repression; Cystathionine; Cysteamine; Cysteine; Fructose; Glucose; Homocysteine; Humans; Liver; Mercaptoethylamines

1957
Accumulation of cystathionine in a homocysteine requiring mutant of Aerobacter aerognes.
    Journal of bacteriology, 1962, Volume: 84

    Topics: Amino Acids; Cystathionine; Cysteine; Enterobacter; Enterobacter aerogenes; Homocysteine

1962
CYSTATHIONINE CLEAVAGE ENZYMES OF NEUROSPORA.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Amino Acid Oxidoreductases; Amino Acids; Butyrates; Cystathionine; Cysteine; Homocysteine; Iodoacetates; L-Lactate Dehydrogenase; Maleates; Neurospora; Pyridoxal Phosphate; Pyruvates; Research; Serine; Sulfhydryl Compounds

1964
O-SUCCINYLHOMOSERINE AS AN INTERMEDIATE IN THE SYNTHESIS OF CYSTATHIONINE BY ESCHERICHIA COLI.
    Journal of general microbiology, 1964, Volume: 36

    Topics: Adenosine Triphosphate; Amino Acids; Chromatography; Coenzyme A; Cystathionine; Cysteine; Escherichia coli; Glucose; Homocysteine; Homoserine; Hot Temperature; Methionine; Research; Streptococcus; Succinates

1964
A mathematical model of the methionine cycle.
    Journal of theoretical biology, 2004, Jan-07, Volume: 226, Issue:1

    Topics: Animals; Computational Biology; Cystathionine; Homocysteine; Methionine; Models, Biological; S-Adenosylhomocysteine; S-Adenosylmethionine

2004
The biosynthesis of cysteine and homocysteine in Methanococcus jannaschii.
    Biochimica et biophysica acta, 2003, Dec-05, Volume: 1624, Issue:1-3

    Topics: Cystathionine; Cysteine; Gas Chromatography-Mass Spectrometry; Homocysteine; Methanococcus

2003
Copper-mediated LDL oxidation by homocysteine and related compounds depends largely on copper ligation.
    Biochimica et biophysica acta, 2004, Jan-20, Volume: 1688, Issue:1

    Topics: Copper; Cystathionine; Cysteine; Homocysteine; Homocystine; Humans; Lipoproteins, LDL; Malondialdehyde; Oxidation-Reduction; Serum Albumin; Time Factors

2004
CSF-methionine is elevated in psychotic patients.
    Journal of neural transmission (Vienna, Austria : 1996), 2004, Volume: 111, Issue:5

    Topics: Adult; Biomarkers; Cystathionine; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Psychotic Disorders; Sex Factors

2004
Response of homocysteine, cystathionine, and methylmalonic acid to vitamin treatment in dialysis patients.
    Clinical chemistry, 2005, Volume: 51, Issue:1

    Topics: Aged; Aged, 80 and over; Cystathionine; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylmalonic Acid; Middle Aged; Renal Dialysis; Vitamin B 12; Vitamin B 6

2005
Alteration of homocysteine catabolism in pre-eclampsia, HELLP syndrome and placental insufficiency.
    Clinical chemistry and laboratory medicine, 2004, Volume: 42, Issue:10

    Topics: Cystathionine; Cystatin C; Cystatins; Female; Folic Acid; HELLP Syndrome; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Methylmalonic Acid; Oxidative Stress; Placental Insufficiency; Pre-Eclampsia; Pregnancy; Severity of Illness Index; Uric Acid; Vitamin B 12; Vitamin B 6

2004
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
    The American journal of clinical nutrition, 2004, Volume: 80, Issue:6

    Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12

2004
Cellular uptake of vitamin B12 in patients with chronic renal failure.
    Nephron. Clinical practice, 2005, Volume: 99, Issue:2

    Topics: Adult; Aged; Cells, Cultured; Cystathionine; Female; Homocysteine; Humans; Kidney Failure, Chronic; Leukocytes, Mononuclear; Male; Methylmalonic Acid; Middle Aged; Vitamin B 12

2005
Disturbed homocysteine and methionine cycle intermediates S-adenosylhomocysteine and S-adenosylmethionine are related to degree of renal insufficiency in type 2 diabetes.
    Clinical chemistry, 2005, Volume: 51, Issue:5

    Topics: Aged; Cystathionine; Cysteine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Folic Acid; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Male; Methionine; Methylmalonic Acid; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcobalamins; Vitamin B 12; Vitamin B 6

2005
Inhibitory effect of copper on cystathionine beta-synthase activity: protective effect of an analog of the human albumin N-terminus.
    Protein and peptide letters, 2005, Volume: 12, Issue:3

    Topics: Albumins; Copper; Cystathionine; Cystathionine beta-Synthase; Homocysteine; Humans; Recombinant Proteins

2005
Modulation of cadmium chloride toxicity by sulphur amino acids in hepatoma cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2006, Volume: 20, Issue:5

    Topics: Cadmium Chloride; Carcinoma, Hepatocellular; Cystathionine; Cysteine; Cytoprotection; Glutathione; Homocysteine; Humans; Tumor Cells, Cultured

2006
Two newborns with nutritional vitamin B12 deficiency: challenges in newborn screening for vitamin B12 deficiency.
    Haematologica, 2005, Volume: 90, Issue:12 Suppl

    Topics: Acyl-CoA Dehydrogenase, Long-Chain; Anemia, Pernicious; Autoimmune Diseases; Biomarkers; Carnitine; Citrates; Cystathionine; False Negative Reactions; Female; Gastric Bypass; Heterozygote; Homocysteine; Humans; Hydroxocobalamin; Infant Food; Infant, Newborn; Malabsorption Syndromes; Male; Mass Spectrometry; Maternal-Fetal Exchange; Methylmalonic Acid; Neonatal Screening; Pregnancy; Pregnancy Complications; Vitamin B 12 Deficiency

2005
Screening of toxicity biomarkers for methionine excess in rats.
    The Journal of nutrition, 2006, Volume: 136, Issue:6 Suppl

    Topics: Amino Acids; Analysis of Variance; Animals; Bilirubin; Biomarkers; Cystathionine; Diet; Gas Chromatography-Mass Spectrometry; Glycine; Hemolysis; Homocysteine; Iron; Male; Methionine; Rats; Rats, Inbred F344; Serine; Spleen

2006
A clinical and laboratory evaluation of methionine cycle-transsulfuration and androgen pathway markers in children with autistic disorders.
    Hormone research, 2006, Volume: 66, Issue:4

    Topics: Androgens; Autistic Disorder; Biomarkers; Child; Child, Preschool; Cystathionine; Cysteine; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; Glutathione; Homocysteine; Humans; Male; Methionine; Models, Biological; Signal Transduction; Sulfurtransferases; Testosterone

2006
Hyperhomocysteinemia decreases circulating high-density lipoprotein by inhibiting apolipoprotein A-I Protein synthesis and enhancing HDL cholesterol clearance.
    Circulation research, 2006, Sep-15, Volume: 99, Issue:6

    Topics: Aged; Animals; Apolipoprotein A-I; Apolipoproteins E; Biological Transport; Cells, Cultured; Cholesterol; Cholesterol, HDL; Coronary Artery Disease; Cystathionine; Hepatocytes; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, HDL; Male; Mice; Mice, Knockout; Middle Aged

2006
Conversion of methionine to cysteine in Bacillus subtilis and its regulation.
    Journal of bacteriology, 2007, Volume: 189, Issue:1

    Topics: Bacillus subtilis; Bacterial Proteins; Carbon-Oxygen Lyases; Cystathionine; Cystathionine beta-Synthase; Cysteine; Gene Expression Regulation, Bacterial; Genes, Bacterial; Homocysteine; Lyases; Methionine; Operon; Promoter Regions, Genetic; Serine; Substrate Specificity

2007
Biomarkers of folate and vitamin B12 are related in blood and cerebrospinal fluid.
    Clinical chemistry, 2007, Volume: 53, Issue:2

    Topics: Adult; Aged; Aging; Biomarkers; Cystathionine; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Middle Aged; Transcobalamins; Vitamin B 12

2007
A new synthesis of S-(beta-amino-beta-carboxyethyl) homocysteine (cystathionine) and S-bis(gamma-amino-gamma -carboxypropyl) sulfide (homolanthionine).
    The Journal of biological chemistry, 1948, Volume: 173, Issue:1

    Topics: Cystathionine; Homocysteine; Sulfides

1948
In Helicobacter pylori, LuxS is a key enzyme in cysteine provision through a reverse transsulfuration pathway.
    Journal of bacteriology, 2010, Volume: 192, Issue:5

    Topics: Bacterial Proteins; Carbon-Sulfur Lyases; Computational Biology; Culture Media; Cystathionine; Cysteine; DNA, Bacterial; Gene Knockout Techniques; Gene Order; Gene Transfer, Horizontal; Gram-Positive Bacteria; Helicobacter pylori; Homocysteine; Metabolic Networks and Pathways; Sequence Analysis, DNA; Sulfur

2010
Residue N84 of yeast cystathionine beta-synthase is a determinant of reaction specificity.
    Biochimica et biophysica acta, 2010, Volume: 1804, Issue:7

    Topics: Alanine; Aspartic Acid; Catalysis; Cystathionine; Cystathionine beta-Synthase; Histidine; Homocysteine; Kinetics; Mutation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Substrate Specificity; Time Factors; Tryptophan

2010
Impaired homocysteine transsulfuration is an indicator of alcoholic liver disease.
    Journal of hepatology, 2010, Volume: 53, Issue:3

    Topics: Adult; Aged; Alcoholism; Aminobutyrates; Biomarkers; Case-Control Studies; Cystathionine; Disease Progression; Female; Homocysteine; Humans; Liver; Liver Cirrhosis, Alcoholic; Liver Diseases, Alcoholic; Male; Methionine; Middle Aged; Sulfur; Young Adult

2010
Pre-steady-state kinetic analysis of enzyme-monitored turnover during cystathionine β-synthase-catalyzed H(2)S generation.
    Biochemistry, 2011, Jan-25, Volume: 50, Issue:3

    Topics: Cystathionine; Cystathionine beta-Synthase; Cysteine; Homocysteine; Hydrogen Sulfide; Kinetics; Models, Chemical; Protein Conformation; Saccharomyces cerevisiae Proteins

2011
Effects of gamma-ray-induced free radicals on the metal content and amino acid composition of human metallothionein-1.
    Journal of biosciences, 2011, Volume: 36, Issue:2

    Topics: Butyrates; Cystathionine; Cysteine; Gamma Rays; Homocysteine; Humans; Metallothionein; Methionine; Serine; Zinc

2011
Vision changes after spaceflight are related to alterations in folate- and vitamin B-12-dependent one-carbon metabolism.
    The Journal of nutrition, 2012, Volume: 142, Issue:3

    Topics: Adult; Astronauts; Carbon Dioxide; Citrates; Cystathionine; Female; Folic Acid; Homocysteine; Humans; Male; Metabolic Networks and Pathways; Methylmalonic Acid; Middle Aged; Models, Biological; Refraction, Ocular; Space Flight; Vision Disorders; Vitamin B 12

2012
Methylation capacity in children with severe cerebral palsy.
    European journal of clinical investigation, 2012, Volume: 42, Issue:7

    Topics: Betaine; Biomarkers; Case-Control Studies; Cerebral Palsy; Child; Child, Preschool; Choline; Cystathionine; DNA Methylation; Erythrocyte Indices; Erythrocyte Membrane; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Queensland; Severity of Illness Index; Uric Acid

2012
Novel thiol- and thioether-containing amino acids: cystathionine and homocysteine families.
    Amino acids, 2013, Volume: 44, Issue:2

    Topics: Aspartic Acid; Cystathionine; Glutamic Acid; Homocysteine; Molecular Structure

2013
Plasma sulfur amino acids and stearoyl-CoA desaturase activity in two Caucasian populations.
    Prostaglandins, leukotrienes, and essential fatty acids, 2013, Volume: 89, Issue:5

    Topics: Adipose Tissue; Aged; Aged, 80 and over; Amino Acids, Sulfur; Cohort Studies; Cross-Sectional Studies; Cystathionine; Cysteine; Diet; Dipeptides; Exercise; Fatty Acids; Female; Glutathione; Homocysteine; Humans; Male; Methionine; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Stearoyl-CoA Desaturase; Surveys and Questionnaires; White People

2013
Oral exposure to the anti-pyridoxine compound 1-amino D-proline further perturbs homocysteine metabolism through the transsulfuration pathway in moderately vitamin B₆ deficient rats.
    The Journal of nutritional biochemistry, 2015, Volume: 26, Issue:3

    Topics: Animals; Asymptomatic Diseases; Biomarkers; Cystathionine; Cystathionine gamma-Lyase; Diet; Disease Models, Animal; Disease Progression; Flax; Homocysteine; Hyperhomocysteinemia; Liver; Male; Non-alcoholic Fatty Liver Disease; Proline; Pyridoxal Phosphate; Pyridoxine; Random Allocation; Rats, Sprague-Dawley; Seeds; Vitamin B 6; Vitamin B 6 Deficiency

2015
Propargylglycine inhibits hypotaurine/taurine synthesis and elevates cystathionine and homocysteine concentrations in primary mouse hepatocytes.
    Amino acids, 2015, Volume: 47, Issue:6

    Topics: Alkynes; Animals; Cells, Cultured; Cystathionine; Cysteine Dioxygenase; Female; Glycine; Hepatocytes; Homocysteine; Male; Mice; Mice, Knockout; Primary Cell Culture; Taurine

2015
Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users.
    The American journal of clinical nutrition, 2015, Volume: 102, Issue:3

    Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Carbon; Contraceptives, Oral; Cystathionine; Dietary Supplements; Female; Glycine; Homocysteine; Humans; Kynurenine; Leucine; Methionine; Methylamines; Multivariate Analysis; Pyridoxal Phosphate; Pyridoxine; Serine; Tryptophan; Vitamin B 6 Deficiency; Young Adult

2015
The association of single nucleotide polymorphisms of the maternal cystathionine-β-synthase gene with early-onset preeclampsia.
    Pregnancy hypertension, 2016, Volume: 6, Issue:1

    Topics: Adult; Biomarkers; Blood Pressure; Case-Control Studies; Cystathionine; Cystathionine beta-Synthase; Cysteine; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Gestational Age; Homocysteine; Humans; Phenotype; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Protective Factors; Risk Factors

2016
A disrupted transsulphuration pathway results in accumulation of redox metabolites and induction of gametocytogenesis in malaria.
    Scientific reports, 2017, 01-16, Volume: 7

    Topics: Animals; Culture Media; Cystathionine; Cysteine; Disease Models, Animal; Erythrocytes; Glutathione; Homocysteine; Humans; Malaria; Mass Spectrometry; Metabolic Networks and Pathways; Mice; Oxidation-Reduction; Plasmodium falciparum; Protozoan Proteins; Sulfur; Transcription Factors; Transcriptional Activation

2017
Effects of high ambient temperature on plasma metabolomic profiles in chicks.
    Animal science journal = Nihon chikusan Gakkaiho, 2018, Volume: 89, Issue:2

    Topics: Amino Acids, Sulfur; Animals; Chickens; Cystathionine; Cysteine; Cystine; Environmental Exposure; Gas Chromatography-Mass Spectrometry; Homocysteine; Hot Temperature; Kynurenine; Molecular Weight; Niacinamide; Oxidative Stress; Quinolinic Acid; Taurine; Tryptophan

2018
The high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) may explain naked mole-rat's distinct methionine metabolite profile compared to mouse.
    GeroScience, 2018, Volume: 40, Issue:4

    Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Enzyme Activation; Homocysteine; Homocystinuria; Methionine; Mice; Mole Rats; S-Adenosylhomocysteine; S-Adenosylmethionine

2018
Identification and characterization of Helicobacter pylori O-acetylserine-dependent cystathionine β-synthase, a distinct member of the PLP-II family.
    Molecular microbiology, 2019, Volume: 112, Issue:2

    Topics: Bacterial Proteins; Binding Sites; Catalytic Domain; Cystathionine; Cystathionine beta-Synthase; Enzyme Stability; Helicobacter pylori; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methionine; Serine; Substrate Specificity

2019
[Effects of methionine on the activity of cystathionine-β-synthase].
    Wei sheng yan jiu = Journal of hygiene research, 2019, Volume: 48, Issue:3

    Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine; Cystathionine beta-Synthase; Homocysteine; Liver; Male; Methionine; Rats; Rats, Wistar

2019
The concomitant lower concentrations of vitamins B6, B9 and B12 may cause methylation deficiency in autistic children.
    The Journal of nutritional biochemistry, 2019, Volume: 70

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Autism Spectrum Disorder; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cystathionine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Male; Mass Spectrometry; Methionine; Methylation; Mutation; Oxidation-Reduction; Phenotype; Vitamin B 12; Vitamin B 6

2019
Assessing computational predictions of the phenotypic effect of cystathionine-beta-synthase variants.
    Human mutation, 2019, Volume: 40, Issue:9

    Topics: Amino Acid Substitution; Computational Biology; Cystathionine; Cystathionine beta-Synthase; Homocysteine; Humans; Phenotype; Precision Medicine

2019
Blockade of the trans-sulfuration pathway in acute pancreatitis due to nitration of cystathionine β-synthase.
    Redox biology, 2020, Volume: 28

    Topics: Animals; Ceruletide; Cystathionine; Cystathionine beta-Synthase; Cysteine; Disease Models, Animal; Glutathione; Homocysteine; Male; Mice; Nitric Oxide Synthase Type II; Pancreatitis; S-Adenosylmethionine; Up-Regulation

2020
L-Cystathionine Protects against Homocysteine-Induced Mitochondria-Dependent Apoptosis of Vascular Endothelial Cells.
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cystathionine; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Protective Agents

2019
Cystathionine β-synthase is involved in cysteine biosynthesis and H
    Scientific reports, 2020, 09-04, Volume: 10, Issue:1

    Topics: Biocatalysis; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; DNA, Complementary; Genes, Protozoan; Heme; Homocysteine; Hydrogen Sulfide; Kinetics; Serine; Toxoplasma

2020
Catalytic specificity of the Lactobacillus plantarum cystathionine γ-lyase presumed by the crystallographic analysis.
    Scientific reports, 2020, 09-10, Volume: 10, Issue:1

    Topics: Catalysis; Crystallography, X-Ray; Cystathionine; Cystathionine gamma-Lyase; Homocysteine; Lactobacillus plantarum; Serine; Substrate Specificity

2020
A sensitive UPLC-MS/MS method for simultaneous quantification of one-carbon metabolites & co-factors in human plasma.
    Journal of pharmaceutical and biomedical analysis, 2022, Sep-20, Volume: 219

    Topics: Carbon; Chromatography, High Pressure Liquid; Chromatography, Liquid; Colorectal Neoplasms; Cystathionine; Homocysteine; Humans; Methionine; Tandem Mass Spectrometry

2022
The Associations of Habitual Intake of Sulfur Amino Acids, Proteins and Diet Quality with Plasma Sulfur Amino Acid Concentrations: The Maastricht Study.
    The Journal of nutrition, 2023, Volume: 153, Issue:7

    Topics: Amino Acids, Sulfur; Cardiovascular Diseases; Cross-Sectional Studies; Cystathionine; Cysteine; Diabetes Mellitus, Type 2; Diet; Female; Homocysteine; Humans; Methionine; Obesity; Taurine

2023
A Methionine-Portioning-Based Medical Nutrition Therapy with Relaxed Fruit and Vegetable Consumption in Patients with Pyridoxine-Nonresponsive Cystathionine-β-Synthase Deficiency.
    Nutrients, 2023, Jul-11, Volume: 15, Issue:14

    Topics: Cystathionine; Cystathionine beta-Synthase; Diet, Protein-Restricted; Fruit; Homocysteine; Homocystinuria; Humans; Methionine; Pyridoxine; Racemethionine; Vegetables

2023