homocysteine and choline
homocysteine has been researched along with choline in 151 studies
Research
Studies (151)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 35 (23.18) | 18.7374 |
1990's | 10 (6.62) | 18.2507 |
2000's | 42 (27.81) | 29.6817 |
2010's | 53 (35.10) | 24.3611 |
2020's | 11 (7.28) | 2.80 |
Authors
Authors | Studies |
---|---|
Bolondi, L; Caletti, GC; Fontana, G; Ventrucci, M | 1 |
Canfield, CJ; McCormick, GJ; Smith, CC | 1 |
Labadie, P | 1 |
Baker, DH; Harter, JM | 1 |
Hieb, WF; Lu, NC; Stokstad, EL | 1 |
Olszewski, AJ | 1 |
Baker, DH; Czarnecki, GL | 1 |
Vance, DE; Yao, ZM | 1 |
Lehmann, J; Tsai, C; Wood, PL | 1 |
Bialkowska, M; McCully, KS; Olszewski, AJ; Rudnicki, S; Szostak, WB | 1 |
Finkelstein, JD; Harris, BJ; Martin, JJ | 1 |
Barak, AJ; Beckenhauer, HC; Tuma, DJ | 1 |
Cheah, KS; Watkins, JC | 1 |
Capitolo, S; Marchioni, GF; Mariani, B | 1 |
Amata, D; Gaggi, R | 1 |
Bandini, S; Monteforte, S | 1 |
Azzena, D | 1 |
Batra, KK; Buehring, KU; Stokstad, EL | 1 |
Rocca, F | 1 |
Bonini, M | 1 |
Demain, AL; White, RF | 1 |
Del Mastro, S; Gaggi, R | 1 |
Khairallah, EA; Wolf, G | 1 |
Daniel, LJ; Lust, G | 2 |
Guttman, HN | 1 |
Ebert, MH; Mudd, SH; Scriver, CR | 1 |
Hoffman, RM | 1 |
Barak, AJ; Tuma, DJ | 1 |
da Costa, KA; Kim, YI; Mason, JB; Miller, JW; Nadeau, M; Selhub, J; Smith, D; Zeisel, SH | 1 |
Henning, SM; Jacob, RA; Swendseid, ME; Wu, MM | 1 |
Pérez de Miguelsanz, J; Ragel, C; Varela-Moreiras, G | 1 |
Baker, DH; Emmert, JL; Garrow, TA | 1 |
Connell, A; Lobley, GE; Revell, D | 1 |
Canty, DJ | 1 |
Bottiglieri, T; Charles, HC; Gray, L; Hyland, K; Jaeken, J; Kahler, SG; Lazeyras, F; Van Hove, JL; Zeisel, SH | 1 |
Glade, MJ | 1 |
Allman-Farinelli, MA; Jacob, RA; Jenden, DJ; Swendseid, ME | 1 |
Incharoensakdi, A; Waditee, R | 1 |
Hirosawa, K; Hishida, A; Ikegaya, N; Katoh, S; Kimura, M; Kumagai, H | 1 |
Kokkinakis, DM; Wick, JB; Zhou, QX | 1 |
Castro, C; Chen, Z; Garrow, T; Genest, J; Laryea, MD; Lussier-Cacan, S; Mar, MH; Rozen, R; Schwahn, BC; Wendel, U; Zeisel, SH | 1 |
Kacprzak, MM; Lewandowska, I; Matthews, RG; Paszewski, A | 1 |
ALEXANDER, GJ | 1 |
FIEDLER, E; GUELZOW, M | 1 |
CRAWFORD, JM; CURTIS, DR; VOORHOEVE, PE; WILSON, VJ | 1 |
VALENCIA, R | 1 |
EDWARDS, CH; EDWARDS, GA; GADSEN, EL | 1 |
KORITZ, SB; MUNCK, A | 1 |
NIMURA, T; SAHASHI, Y; SUZUKI, T | 1 |
Bleie, Ø; Holm, PI; Lien, EA; Nordrehaug, JE; Nygård, O; Refsum, H; Ueland, PM | 1 |
Castro, C; Garrow, TA; Leclerc, D; Lussier-Cacan, S; Mar, MH; Rozen, R; Schwahn, BC; Wendel, U; Zeisel, SH | 1 |
Blom, HJ; den Heijer, M; Holm, PI; Keijzer, MB; Midttun, Ø; Ueland, PM; Vollset, SE | 1 |
Zeisel, SH | 3 |
da Costa, KA; Fischer, LM; Gaffney, CE; Zeisel, SH | 1 |
Olthof, MR; Verhoef, P | 1 |
Clarke, R; Holm, PI; Melse-Boonstra, A; Olthof, M; Ueland, PM; Verhoef, P | 1 |
Fokkema, MR; Holm, PI; Muskiet, FA; Ueland, PM; van der Dijs, FP; Velzing-Aarts, FV | 1 |
Brink, EJ; Katan, MB; Olthof, MR; Verhoef, P | 1 |
Brody, LC; Conley, M; Cox, C; Daly, SF; Kirke, PN; Mills, JL; Molloy, AM; Scott, JM; Ueland, PM | 1 |
Beers, KW; Blair, ME; Emmert, JL; Fanatico, AC; Pillai, PB | 1 |
Cho, E; Colditz, GA; Dougherty, L; Jacques, P; Selhub, J; Willett, WC; Zeisel, SH | 1 |
Maloney, CA; Rees, WD; Wilson, FA | 1 |
Nakata, R; Shigematsuo, N; Yagisawa, M | 1 |
Blair, ME; Emmert, JL; Fanatico, AC; Pillai, PB | 1 |
Blouet, C; Daré, S; Hammiche, A; Huneau, JF; Mariotti, F; Tomé, D | 1 |
Grotmol, T; Holm, PI; Hustad, S; Schneede, J; Ueland, PM; Vollset, SE | 1 |
Davidson, AG; Innis, SM; James, SJ; Melynk, S | 1 |
Bots, ML; Dalmeijer, GW; Olthof, MR; van der Schouw, YT; Verhoef, P | 1 |
Blom, HJ; Clarke, R; de Groot, LC; Eussen, SJ; Hoefnagels, WH; Ueland, PM; van Staveren, WA | 1 |
Chiuve, SE; Dougherty, LW; Giovannucci, EL; Hankinson, SE; Rimm, EB; Willett, WC; Zeisel, SH | 1 |
Li, Z; Vance, DE | 1 |
Antonopoulou, S; Detopoulou, P; Panagiotakos, DB; Pitsavos, C; Stefanadis, C | 1 |
Atkinson, W; Chambers, ST; Elmslie, J; George, PM; Lever, M | 1 |
Brennan, L; Jin, Y | 1 |
Bleie, Ø; Konstantinova, SV; Nygård, O; Tell, GS; Ueland, PM; Vollset, SE | 1 |
Morita, T; Ohuchi, S; Setoue, M; Sugiyama, K | 2 |
Carageorgiou, H; Feskou, I; Galanopoulou, P; Liapi, C; Tsakiris, S; Zarros, A | 1 |
Abratte, CM; Caudill, MA; Hung, J; Li, R; Moriarty, DJ; Wang, W | 1 |
Abratte, CM; Caudill, MA; Li, R; Maletz, CV; Solis, C; Veenema, K; Wang, W | 1 |
Calder, AG; Holtrop, G; Lobley, GE; O'Kennedy, N; Rees, WD; van den Borne, JJ; Wilson, FA | 1 |
Caudill, MA; Hinkis, S; Ivanov, A; Nash-Barboza, S | 1 |
Atkinson, W; Chambers, ST; Elmslie, J; George, PM; Lever, M; Slow, S | 1 |
Kawakami, Y; Morita, T; Ohuchi, S; Sugiyama, K | 1 |
Batra, V; Devasagayam, TP; Sridhar, S | 1 |
Audonnet, S; Beck, B; Blaise, S; Bossenmeyer-Pourié, C; Daval, JL; Guéant, JL; Koziel, V; Ortiou, S; Pourié, G; Rio, MC; Tomasetto, C | 1 |
Caudill, MA; Chan, J; Deng, L; Mikael, LG; Pickell, L; Rozen, R; Wu, Q; Yan, J | 1 |
Cho, E; Dougherty, L; Giovannucci, E; Jacques, PF; Lee, JE; Selhub, J; Zeisel, SH | 1 |
Caudill, MA; Christensen, KE; Deng, L; Rozen, R; Wang, X; Wu, Q | 1 |
Garrow, TA; Gupta, S; Jiracek, J; Kruger, WD; Li, L; Rozen, R; Schalinske, KL; Strakova, J; Williams, KT | 1 |
Caudill, MA; West, AA | 1 |
Chen, CS; Juo, SH; Ko, CH; Kuo, YT; Lee, CC; Li, CW; Lin, HF; Liu, GC; Tsai, HY; Yeh, YC; Yen, CF | 1 |
Böhlke, M; Broersen, LM; Hageman, RJ; Kamphuis, PJ; Maher, TJ; van Wijk, N; Watkins, CJ; Wurtman, RJ | 1 |
Carducci, MA; Herman, JG; Shabbeer, S; Simons, BW; Williams, SA | 1 |
Bonham, MP; Duffy, ME; McCormack, JM; McNulty, H; Molloy, AM; Robson, PJ; Scott, JM; Strain, JJ; Ueland, PM; Wallace, JM; Walsh, PM; Ward, M | 1 |
Boyd, RN; Davies, PS; Moxon-Lester, L; Obeid, R; Schoendorfer, NC; Sharp, N; Vitetta, L | 1 |
Allen, RH; Beaudin, AE; Perry, CA; Stabler, SP; Stover, PJ | 1 |
Anderson, SE; Calder, AG; Holtrop, G; Lobley, GE; Rees, WD; Wilson, FA | 1 |
Bedell, BJ; Caudill, MA; Deng, L; Jadavji, NM; Leclerc, D; Malysheva, O; Rozen, R | 1 |
Liu, Y; Liu, YQ; Mori, M; Morita, T; Sugiyama, K | 1 |
Caudill, M; Jiang, X; Mikael, LG; Pancer, J; Rozen, R; Wu, Q | 1 |
Abarinov, EV; Allen, RH; Ash, JA; Caudill, MA; Field, MS; Malysheva, OV; Shields, KS; Stabler, SP; Stover, PJ; Strupp, BJ | 1 |
Bonham, MP; Davidson, PW; Henderson, J; Kobrosly, RW; McAfee, AJ; McSorley, EM; Mulhern, MS; Myers, GJ; Shamlaye, CF; Strain, JJ; Thurston, SW; Ueland, PM; van Wijngaarden, E; Wallace, JM; Watson, GE | 1 |
Chang, Y; Chen, L; Jin, T; Tan, Y; Wang, L; Wei, J; Zhu, H | 1 |
Cole, D; Cox, SE; da Costa, KA; Dominguez-Salas, P; Dyer, RA; Fulford, AJ; Hennig, BJ; Innis, SM; Moore, SE; Prentice, AM; Waterland, RA; Zeisel, SH | 1 |
Ballesteros, M; Berrocal-Zaragoza, MI; Cavallé-Busquets, P; Fernandez-Ballart, JD; Fernàndez-Roig, S; Murphy, MM; Salat-Batlle, J; Ueland, PM | 1 |
Cao, JM; Cao, Y; Gong, XJ; Guo, J; Guo, M; Li, D; Lun, YZ; Luo, N; Sun, WP; Tian, YJ; Zhou, SS | 1 |
Ali, NS; Michels, KB; Osterhues, A | 1 |
Obeid, R | 1 |
Benoist, JF; Blom, HJ; Imbard, A | 1 |
Bae, S; Bailey, LB; Beresford, SA; Brown, EC; Buck, K; Caudill, MA; Cheng, TY; Hou, L; Malysheva, O; Maneval, DR; Miller, JW; Neuhouser, ML; Song, X; Ulrich, CM; Xiao, L; Zheng, Y | 1 |
Bahous, RH; Bedell, BJ; Caudill, MA; Deng, L; Grand'maison, M; Jadavji, NM; Malysheva, O; Rozen, R | 1 |
Bandeira, IC; Blom, HJ; Castro, K; D'Almeida, V; de Souza, CF; Imbard, A; Leistner-Segal, S; Nalin, T; Poloni, S; Schwartz, IV; Spritzer, PM; Tonon, T | 1 |
Bertoia, ML; Cooke, JP; Joosten, MM; Mittleman, MA; Mukamal, KJ; Pai, JK; Rimm, EB | 1 |
Chambers, ST; Elmslie, JL; George, PM; Krebs, JD; Lever, M; Lunt, H; McEntyre, CJ; Parry-Strong, A; Slow, S | 1 |
Bai, SY; Briggs, DI; Vickers, MH | 1 |
Ishii, D; Kawai, K; Mashimo, Y; Matsuda, S; Matsuzawa, D; Shimizu, E; Sutoh, C; Tomizawa, H | 1 |
Allen, RH; Bae, S; Caudill, MA; Jiang, X; Malysheva, O; Perry, CA; Stabler, SP; West, AA; Yan, J | 1 |
Han, F; Huang, Z; Liu, Y; Lu, J; Sugiyama, K; Sun, L; Wang, Q | 1 |
Berge, RK; Bjørndal, B; Lysne, V; Nordrehaug, JE; Nygård, O; Skorve, J; Vik, R | 1 |
Bertolo, RF; Brunton, JA; Harding, SV; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
Herrmann, W; Hurtig-Wennlöf, A; Nilsson, TK; Obeid, R; Owen, JR; Sjöström, M; Zeisel, S | 1 |
Alshaikh, B; Bennett, MJ; Maqbool, A; Mascarenhas, M; Schall, JI; Stallings, VA | 1 |
Chen, Y; Hong, Y; Wang, W; Xiao, Z; Yu, L | 1 |
Chen, NN; Guo, M; Li, D; Sun, WP; Zhai, MZ; Zhou, SS; Zhou, Y | 1 |
Aris, IM; Chong, MF; Chong, YS; Fortier, MV; Gluckman, PD; Godfrey, KM; Kramer, MS; Lee, YS; Quah, PL; Saw, SM; Tint, MT; van Lee, L; Yap, FK | 1 |
Chauhan, A; Jaiswal, SK; Kumar, A; Lakhotia, AR; Rai, AK; Sukla, KK | 1 |
Bhadelia, RA; Johnson, EJ; Lichtenstein, AH; Roe, AJ; Rogers, GT; Rosenberg, IH; Scott, TM; Smith, CE; Zeisel, SH; Zhang, S | 1 |
Che, L; Chen, Y; Fang, Z; Feng, B; Li, J; Lin, Y; Liu, H; Mou, D; Wang, J; Xu, S | 1 |
Ray, D; Richardson, BC; Strickland, FM | 1 |
Chmurzynska, A; Malinowska, AM; Mlodzik, MA; Nowacka-Woszuk, J; Radziejewska, A; Szwengiel, A | 1 |
Dahdoul, T; Nijhout, HF; Reed, MC; Sadre-Marandi, F | 1 |
Caccamo, A; Dave, N; Ferreira, E; Huentelman, MJ; Naymik, M; Oddo, S; Piras, IS; Tran, A; Velazquez, R; Winslow, W | 1 |
Ali, MA; Bakir, MB; Kamel, MA; Khalifa, EA; Refaat, R; Salama, MA | 1 |
Frenkel, EP; Hoffman, RM; Kokkinakis, DM | 1 |
Cheng, ZY; Du, YF; Shi, HF; Wang, XL; Wei, Y; Wu, TC; Yang, J; Zuo, XF | 1 |
Barlik, M; Chmurzynska, A; Drews, K; KurzawiŃska, G; Malinowska, AM; Radziejewska, A; Różycka, A; Seremak-Mrozikiewicz, A; Wolski, H | 1 |
Goyal, A; Gupta, JK; Narayan Yadav, H; Qureshi, SS | 1 |
Bae, S; Caudill, MA; Jiang, X; King, JH; Klatt, KC; Kwan, STC; Malysheva, OV; Roberson, MS; Yan, J | 1 |
Bozack, AK; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Parvez, F; Shahriar, H; Siddique, AB; Slavkovich, V; Uddin, MN | 1 |
Elango, R | 1 |
Andraos, S; Cameron-Smith, D; Chia, PHP; D'Souza, RF; Gillies, NA; Knowles, SO; Milan, AM; Mitchell, CJ; Mitchell, SM; Ramzan, F; Roy, NC; Sharma, P; Sjödin, A; Wagner, KH; Zeng, N | 1 |
Cameron-Smith, D; Franzke, B; Gillies, NA; Hofmann, M; Milan, AM; Oesen, S; Roy, NC; Schober-Halper, B; Strasser, EM; Tosevska, A; Wagner, KH; Wessner, B | 1 |
Chmurzynska, A; Muzsik-Kazimierska, A; Nikrandt, G; Szwengiel, A | 1 |
Cariou, B; Croyal, M; Gand, E; Goronflot, T; Hadjadj, S; Jacobi, D; Le May, C; Prieur, X; Ragot, S; Saulnier, PJ; Trochu, JN; Wargny, M | 1 |
Arthurs, AL; Jankovic-Karasoulos, T; Roberts, CT; Smith, MD; Williamson, JM | 1 |
Li, C; Liu, W; Lv, B; Qin, J; Xue, J; Xue, Z; Yi, N | 1 |
Du, YF; Gong, XL; Shi, HF; Wang, XL; Wei, Y; Wu, TC; Zhao, YY | 1 |
Reviews
12 review(s) available for homocysteine and choline
Article | Year |
---|---|
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1984 |
Betaine, metabolic by-product or vital methylating agent?
Topics: Alcohol Oxidoreductases; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Diet; Ethanol; Homocysteine; Humans; Liver; Methionine; Methotrexate; Methylation; Methyltransferases; Oxidation-Reduction; Rats; Tetrahydrofolates | 1983 |
Nutritional importance of choline for brain development.
Topics: Animals; Apoptosis; Brain; Cell Division; Cell Movement; Cell Proliferation; Choline; Female; Folic Acid; Gene Expression Regulation, Developmental; Homocysteine; Humans; Male; Memory; Neurons; Pregnancy | 2004 |
Effects of betaine intake on plasma homocysteine concentrations and consequences for health.
Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Folic Acid; Homocysteine; Humans; Lipids | 2005 |
Sulfur amino acid metabolism in pregnancy: the impact of methionine in the maternal diet.
Topics: Amino Acids, Sulfur; Animals; Choline; Diet; DNA Methylation; Drug Interactions; Endocrine System; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Methylation; Nutritional Requirements; Pregnancy; Proteins; S-Adenosylmethionine | 2006 |
Phosphatidylcholine and choline homeostasis.
Topics: Animals; Cholesterol, VLDL; Choline; Homeostasis; Homocysteine; Humans; Mice; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase | 2008 |
Genetic variation: impact on folate (and choline) bioefficacy.
Topics: Biological Availability; Choline; Epistasis, Genetic; Folic Acid; Genetic Variation; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2) | 2010 |
The role of folic acid fortification in neural tube defects: a review.
Topics: Biological Availability; Choline; Edible Grain; Female; Folic Acid; Folic Acid Antagonists; Food, Fortified; Homocysteine; Humans; Neural Tube Defects; Nutritional Requirements; Pregnancy; Recommended Dietary Allowances; United States; Vitamin B 12 | 2013 |
The metabolic burden of methyl donor deficiency with focus on the betaine homocysteine methyltransferase pathway.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Dietary Supplements; Disease Models, Animal; DNA Methylation; Fasting; Fatty Liver; Folic Acid; Homocysteine; Humans; Liver; Metabolic Networks and Pathways; Methionine; Muscular Diseases; S-Adenosylmethionine | 2013 |
Neural tube defects, folic acid and methylation.
Topics: Animals; Choline; Folic Acid; Homocysteine; Humans; Methylation; Neural Tube Defects; Neurulation; Vitamin B 12; Vitamin B Complex | 2013 |
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur | 2020 |
High Folate, Perturbed One-Carbon Metabolism and Gestational Diabetes Mellitus.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Carbon; Choline; Diabetes, Gestational; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Micronutrients; Neural Tube Defects; Pregnancy; Thymidylate Synthase; Vitamin B 12 | 2022 |
Trials
23 trial(s) available for homocysteine and choline
Article | Year |
---|---|
[Therapeutic effect of a pharmacologic combination of choleretics and digestive enzymes in exocrine pancreatic insufficiency].
Topics: Adolescent; Adult; Aged; Amylases; Celiac Disease; Cholagogues and Choleretics; Choline; Clinical Trials as Topic; Crohn Disease; Drug Combinations; Drug Evaluation; Female; Gastroenteritis; Homocysteine; Humans; Male; Middle Aged; Pancreatic Neoplasms; Pancreatitis; Pronase; Silicone Elastomers; Vitamin B 12; Whipple Disease | 1975 |
[Treatment of liver damage during a course of tuberculosis and chronic pulmonary diseases. Necessity of treatment and new trends].
Topics: Bilirubin; Choline; Chronic Disease; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Female; Homocysteine; Humans; Lactones; Liver; Liver Diseases; Liver Function Tests; Lung Diseases; Male; Peritonitis; Pleurisy; Silicotuberculosis; Transaminases; Tuberculosis, Pulmonary; Vitamin B 12 | 1974 |
[Controlled clinical trial of a new combination of phosphorylcholine, homocysteine-gamma-thiolactone and vitamin B 12 in the parenteral treatment of chronic hepatopathies].
Topics: Adult; Aged; Choline; Chronic Disease; Drug Combinations; Evaluation Studies as Topic; Female; Homocysteine; Humans; Lactones; Liver Diseases; Liver Function Tests; Male; Middle Aged; Phosphoric Acids; Vitamin B 12 | 1974 |
Folate nutriture alters choline status of women and men fed low choline diets.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Choline; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipids; Male; Methionine; Methylation; Middle Aged; Nutritional Physiological Phenomena; Nutritional Status; Phosphatidylcholines; Reference Values; S-Adenosylmethionine | 1999 |
Betaine as a determinant of postmethionine load total plasma homocysteine before and after B-vitamin supplementation.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Betaine; Choline; Coronary Angiography; Dietary Supplements; Drug Administration Schedule; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Methionine; Methyltransferases; Middle Aged; Sarcosine; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2004 |
Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load.
Topics: Adult; Analysis of Variance; Animals; Choline; Choline Deficiency; Cross-Over Studies; Homocysteine; Humans; Lipotropic Agents; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Middle Aged; Nutritional Status; Pilot Projects | 2005 |
Betaine concentration as a determinant of fasting total homocysteine concentrations and the effect of folic acid supplementation on betaine concentrations.
Topics: Administration, Oral; Aged; Betaine; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged | 2005 |
Choline supplemented as phosphatidylcholine decreases fasting and postmethionine-loading plasma homocysteine concentrations in healthy men.
Topics: Administration, Oral; Choline; Cross-Sectional Studies; Double-Blind Method; Fasting; Homocysteine; Humans; Kidney; Liver; Male; Methionine; Middle Aged; Phosphatidylcholines | 2005 |
Homocysteine remethylation in young broilers fed varying levels of methionine, choline, and betaine.
Topics: Animals; Betaine; Chickens; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Homocysteine; Methionine; Methylation | 2006 |
Homocysteine remethylation in broilers fed surfeit choline or betaine and varying levels and sources of methionine from eight to twenty-two days of age.
Topics: Aging; Animal Feed; Animals; Betaine; Chickens; Choline; Dose-Response Relationship, Drug; Homocysteine; Methionine; Methylation | 2006 |
The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people.
Topics: Aged; Attention; Betaine; Choline; Cognition; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Memory; Neuropsychological Tests; Psychomotor Performance; Sarcosine; Vitamin B 12; Vitamin B Complex | 2007 |
Dietary and supplementary betaine: acute effects on plasma betaine and homocysteine concentrations under standard and postmethionine load conditions in healthy male subjects.
Topics: Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Betaine; Choline; Cross-Over Studies; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Homocysteine; Humans; Male; Methionine; Sarcosine; Statistics, Nonparametric | 2008 |
Dietary and supplementary betaine: effects on betaine and homocysteine concentrations in males.
Topics: Adult; Betaine; Biomarkers; Choline; Creatinine; Cross-Over Studies; Diet; Dietary Supplements; Folic Acid; Homocysteine; Humans; Lipids; Male; Sarcosine; Time Factors; Vitamin B 12; Young Adult | 2009 |
Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women.
Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Northern Ireland; Nutritional Status; Patient Compliance; Postmenopause | 2012 |
Body composition in patients with classical homocystinuria: body mass relates to homocysteine and choline metabolism.
Topics: Adiposity; Adolescent; Adult; Amino Acids; Bone Density; Cholesterol, HDL; Choline; Ethanolamine; Female; Homocysteine; Homocystinuria; Humans; Male | 2014 |
Extreme urinary betaine losses in type 2 diabetes combined with bezafibrate treatment are associated with losses of dimethylglycine and choline but not with increased losses of other osmolytes.
Topics: Adult; Aged; Betaine; Bezafibrate; Choline; Diabetes Mellitus, Type 2; Female; Glycerylphosphorylcholine; Homocysteine; Humans; Hypolipidemic Agents; Inositol; Male; Middle Aged; Sarcosine; Taurine; Young Adult | 2014 |
Vitamin B-12 Status Differs among Pregnant, Lactating, and Control Women with Equivalent Nutrient Intakes.
Topics: Adult; Biomarkers; Breast Feeding; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Energy Intake; Female; Healthy Volunteers; Homocysteine; Humans; Lactation; Methylmalonic Acid; Micronutrients; Postpartum Period; Pregnancy; Recommended Dietary Allowances; Vitamin B 12; Young Adult | 2015 |
Choline supplementation alters some amino acid concentrations with no change in homocysteine in children with cystic fibrosis and pancreatic insufficiency.
Topics: Adolescent; Amino Acids; Amino Acids, Branched-Chain; Child; Child, Preschool; Choline; Cystic Fibrosis; Dietary Supplements; Exocrine Pancreatic Insufficiency; Female; Homocysteine; Humans; Male; Methionine; Placebos | 2016 |
Maternal methyl donor supplementation during gestation counteracts bisphenol A-induced oxidative stress in sows and offspring.
Topics: Actins; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Benzhydryl Compounds; Betaine; Catalase; Choline; Diet; Dietary Supplements; Female; Folic Acid; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Malondialdehyde; Maternal Nutritional Physiological Phenomena; Oxidative Stress; Phenols; Placenta; Pregnancy; Superoxide Dismutase; Swine; Vitamin B 12 | 2018 |
Maternal choline supplementation alters vitamin B-12 status in human and murine pregnancy.
Topics: Adult; Animals; Betaine-Homocysteine S-Methyltransferase; Choline; Choline Dehydrogenase; Dietary Supplements; Female; Gene Expression Regulation; Homeodomain Proteins; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methylmalonic Acid; Mice, Mutant Strains; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Trimester, Third; Transcription Factors; Vitamin B 12; Young Adult | 2019 |
Betaine and choline status modify the effects of folic acid and creatine supplementation on arsenic methylation in a randomized controlled trial of Bangladeshi adults.
Topics: Adult; Arsenic; Betaine; Choline; Creatine; Dietary Supplements; Environmental Exposure; Folic Acid; Homocysteine; Humans; Methylation | 2021 |
Responsiveness of one-carbon metabolites to a high-protein diet in older men: Results from a 10-wk randomized controlled trial.
Topics: Aged; Betaine; Carbon; Choline; Diet; Diet, High-Protein; Folic Acid; Homocysteine; Humans; Male; Vitamin B Complex | 2021 |
Nutritional supplementation alters associations between one-carbon metabolites and cardiometabolic risk profiles in older adults: a secondary analysis of the Vienna Active Ageing Study.
Topics: Aged; Aging; Betaine; Carbon; Cardiovascular Diseases; Choline; Dietary Supplements; Female; Homocysteine; Humans; Male | 2022 |
Other Studies
116 other study(ies) available for homocysteine and choline
Article | Year |
---|---|
Plasmodium knowlesi: in vitro biosynthesis of methionine and thymidylic acid.
Topics: Animals; Betaine; Cells, Cultured; Choline; Erythrocytes; Folic Acid; Formaldehyde; Formyltetrahydrofolates; Haplorhini; Histidine; Homocysteine; Macaca mulatta; Methionine; Plasmodium; Sarcosine; Serine; Thymidine Monophosphate; Thymine Nucleotides | 1977 |
[Methyls of biological importance].
Topics: Betaine; Carnitine; Choline; Dealkylation; Homocysteine; Humans; Lipid Metabolism; Methane; Methionine; Methylation; Phosphatidylcholines | 1979 |
Sulfur amino acid activity of D- and L-homocystein for chicks.
Topics: Animals; Chickens; Choline; Cysteine; Diet; Female; Homocysteine; Isomerism; Male; Methionine | 1978 |
Effect of vitamin B12 and folate on biosynthesis of methionine from homocysteine in the nematode Caenorhabditis briggsae.
Topics: Animals; Choline; Folic Acid; Homocysteine; Methionine; Nematoda; Vitamin B 12 | 1976 |
Homocysteine content of plasma in ischemic heart disease, the reducing effect of pyridoxine, folate, cobalamin, choline, riboflavin and troxerutin. Correction of a calculation error.
Topics: Amino Acids; Anticoagulants; Choline; Coronary Disease; Folic Acid; Homocysteine; Humans; Hydroxyethylrutoside; Pyridoxine; Riboflavin; Vitamin B 12 | 1991 |
Transmethylation of homocysteine to methionine: efficiency in the rat and chick.
Topics: Animals; Betaine; Body Weight; Chickens; Choline; Diet; Homocysteine; Male; Methionine; Methylation; Rats; Rats, Inbred Strains; Sarcosine; Tetrahydrofolates | 1985 |
Head group specificity in the requirement of phosphatidylcholine biosynthesis for very low density lipoprotein secretion from cultured hepatocytes.
Topics: Animals; Apolipoproteins; Betaine; Cells, Cultured; Choline; Chromatography, High Pressure Liquid; Deanol; Ethanolamine; Ethanolamines; Homocysteine; Lipoproteins; Lipoproteins, VLDL; Liver; Male; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; Triglycerides | 1989 |
Homocysteic acid as a putative excitatory amino acid neurotransmitter: I. Postsynaptic characteristics at N-methyl-D-aspartate-type receptors on striatal cholinergic interneurons.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Animals; Choline; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; Homocysteine; Interneurons; Magnesium; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereoisomerism; Tachyphylaxis; Tiletamine | 1988 |
Reduction of plasma lipid and homocysteine levels by pyridoxine, folate, cobalamin, choline, riboflavin, and troxerutin in atherosclerosis.
Topics: Adult; Anticoagulants; Choline; Coronary Artery Disease; Coronary Disease; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hydroxyethylrutoside; Lipids; Male; Middle Aged; Pyridoxine; Riboflavin; Vitamin B 12 | 1989 |
Methionine metabolism in mammals. The methionine-sparing effect of cystine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine; Cystathionine beta-Synthase; Cystine; Diet; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1988 |
Ethanol, the choline requirement, methylation and liver injury.
Topics: Animals; Betaine; Choline; Ethanol; Folic Acid; Homocysteine; Liver; Methionine; Methylation; Rats; Tetrahydrofolates | 1985 |
Further syntheses in the study of structure-activity relationships of neuropharmacologically active amino acids.
Topics: Amino Alcohols; Animals; Aspartic Acid; Cats; Central Nervous System; Choline; Cysteine; Homocysteine; Muscle Spindles; Neurons; Serine; Sulfinic Acids | 1965 |
[Action of 1:1 combination of phosphorylcholine and homocysteine on liver function, biliary secretion and cholesterolemia in the rat].
Topics: Animals; Bile; Cholesterol; Choline; Drug Therapy, Combination; Female; Homocysteine; Liver; Rats | 1974 |
[Clinical trial of a new hepatoprotective preparation].
Topics: Alcoholism; Cholelithiasis; Choline; Diabetes Complications; Drug Combinations; Homocysteine; Humans; Lactones; Liver Diseases; Phosphoric Acids; Vitamin B 12 | 1972 |
The effect of methionine on folic acid and histidine metabolism in perfused rat liver.
Topics: Animals; Betaine; Carbon Dioxide; Carbon Isotopes; Choline; Deficiency Diseases; Drug Synergism; Ethionine; Folic Acid; Formates; Glutamates; Histidine; Homocysteine; Liver; Male; Methionine; Oxidation-Reduction; Peptides; Perfusion; Rats; Tetrahydrofolates; Vitamin B 12 Deficiency | 1972 |
[Clinical experience with a new hepatoprotector].
Topics: Adolescent; Adult; Bilirubin; Choline; Gastrointestinal Diseases; Hepatitis; Homocysteine; Humans; Lactones; Liver; Liver Diseases; Male; Middle Aged; Transaminases | 1969 |
[A hepato-protector in the treatment of long bed-ridden old persons affected with chronic diseases].
Topics: Aged; Choline; Chronic Disease; Homocysteine; Humans; Liver; Vitamin B 12 | 1969 |
Catabolism of betaine and its relationship to cobalamin overproduction.
Topics: Betaine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Choline; Coenzyme A; Glycine; Homocysteine; Methionine; Methylation; Nucleosides; Porphyrins; Pseudomonas; S-Adenosylmethionine; Succinates; Sucrose; Vitamin B 12 | 1971 |
[Protective effect of phosphorylcholine, homocysteine and their combination 1:1 in experimental hepatic lesions rats: comparison with the activity of choline and cysteine].
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Choline; Cysteine; Dietary Fats; Drug Synergism; Guinea Pigs; Homocysteine; Liver; Male; Mice; Rats | 1969 |
Growth-promoting and lipotropic effect of carnitine in rats fed diets limited in protein and methionine.
Topics: Amino Acids; Animals; Betaine; Carnitine; Choline; Growth; Homocysteine; Lipid Metabolism; Liver; Male; Methionine; Protein Deficiency; Quaternary Ammonium Compounds; Rats; Threonine | 1965 |
The biosynthesis of the methyl groups of choline in Ochromonas malhamensis.
Topics: Alkylation; Amino Alcohols; Choline; Eukaryota; Folic Acid; Homocysteine; In Vitro Techniques; Methionine; Microsomes; Mitochondria; Nucleosides; Phosphatidylcholines; Subcellular Fractions; Vitamin B 12 | 1966 |
First defined media for leptomonas spp. from insects.
Topics: Choline; Culture Media; Eukaryota; Glycine; Homocysteine; Insecta; Lactones; Methionine; Pantothenic Acid; Vitamin B 12 | 1966 |
Labile methyl group balances in the human: the role of sarcosine.
Topics: Adolescent; Child; Choline; Cystine; Diet; Female; Glycine; Homocysteine; Humans; Male; Methionine; Methylation; Nitrogen; Phosphatidylcholines; Sarcosine | 1980 |
Severe folate deficiency causes secondary depletion of choline and phosphocholine in rat liver.
Topics: Animals; Body Weight; Choline; Diet; Folic Acid; Folic Acid Deficiency; Homocysteine; Liver; Male; Phosphorylcholine; Rats; Rats, Sprague-Dawley | 1994 |
Homocysteine increases as folate decreases in plasma of healthy men during short-term dietary folate and methyl group restriction.
Topics: Adult; Choline; Diet; Folic Acid; Folic Acid Deficiency; Glycine max; Homocysteine; Humans; Male; Methionine; Middle Aged; Nutritional Requirements; Nutritional Status; Vitamin B 12 | 1994 |
Choline deficiency and methotrexate treatment induces marked but reversible changes in hepatic folate concentrations, serum homocysteine and DNA methylation rates in rats.
Topics: Animals; Choline; Choline Deficiency; DNA Modification Methylases; Folic Acid; Folic Acid Antagonists; Homocysteine; Liver; Male; Methotrexate; Methylation; Rats; Rats, Wistar | 1995 |
Hepatic betaine-homocysteine methyltransferase activity in the chicken is influenced by dietary intake of sulfur amino acids, choline and betaine.
Topics: Amino Acids, Sulfur; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Chickens; Choline; Cystine; Diet; Dose-Response Relationship, Drug; Female; Homocysteine; Liver; Male; Methionine; Methyltransferases; Random Allocation | 1996 |
The importance of transmethylation reactions to methionine metabolism in sheep: effects of supplementation with creatine and choline.
Topics: Animals; Choline; Creatine; Homocysteine; Methionine; Methylation; Sheep; Wool | 1996 |
Determinants of plasma homocysteine.
Topics: Choline; Homocysteine; Humans; Nutritional Status; Phosphatidylcholines | 1998 |
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
Topics: Amino Acid Metabolism, Inborn Errors; Benzoic Acid; Brain Diseases; Choline; Coma; Female; Glycine; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methionine; Methylation; Phosphatidylcholines; S-Adenosylmethionine; Seizures; Serine; Tetrahydrofolates | 1998 |
Workshop on Folate, B12, and Choline. Sponsored by the Panel on Folate and other B vitamins of the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine, Washington, D.C., March 3-4,
Topics: Biological Availability; Biomarkers; Cardiovascular Diseases; Choline; Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Male; Neoplasms; Neural Tube Defects; Nutrition Policy; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Purification and kinetic properties of betaine-homocysteine methyltransferase from Aphanothece halophytica.
Topics: Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Chromatography, Agarose; Chromatography, Gel; Cyanobacteria; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methyltransferases; Molecular Weight; Sarcosine | 2001 |
Renal tubulointerstitial injury in weanling rats with hyperhomocysteinemia.
Topics: Age Factors; Animal Feed; Animals; Choline; Folic Acid; Homocysteine; Hyperhomocysteinemia; Methionine; Nephritis, Interstitial; Rats; Rats, Inbred F344; Weaning | 2002 |
Metabolic response of normal and malignant tissue to acute and chronic methionine stress in athymic mice bearing human glial tumor xenografts.
Topics: Animals; Brain Neoplasms; Carbon-Sulfur Lyases; Choline; Choline Deficiency; Glioma; Homocysteine; Humans; Liver; Methionine; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2002 |
Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency.
Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Dose-Response Relationship, Drug; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Liver; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Mice; Mice, Knockout; Models, Biological; Oxidoreductases; Phosphorylcholine | 2003 |
Transcriptional regulation of methionine synthase by homocysteine and choline in Aspergillus nidulans.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aspergillus nidulans; Base Sequence; Betaine; Choline; Cloning, Molecular; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Homocysteine; Methionine; Models, Biological; Molecular Sequence Data; RNA, Messenger; Transcription, Genetic | 2003 |
Choline biogenesis II. The effect of homocysteine on serine metabolism.
Topics: Choline; Cysteine; Homocysteine; Humans; Serine | 1961 |
[Ethionine pancreatitis in the rat. II. Attempts to prevent ethionine injury by methionine, cysteine-homocysteine, choline and betaine].
Topics: Animals; Betaine; Choline; Cysteine; Ethionine; Homocysteine; Methionine; Pancreatitis; Rats | 1960 |
EXCITATION OF CEREBELLAR NEURONES BY ACETYLCHOLINE.
Topics: Acetylcholine; Brain; Cats; Cerebellum; Choline; Electrophysiological Phenomena; Electrophysiology; Homocysteine; Neurochemistry; Neurons; Nicotine; Research | 1963 |
[INFLUENCE OF VARIOUS METHYLATED SUBSTANCES SUPPLEMENTING SOJA FLOUR ON THE BIOSYNTHESIS OF TOTAL COBALAMINES AND VITAMINE B-12 BY STREPTOMYCES OLIVACEUS].
Topics: Alkaloids; Choline; Corrinoids; Culture Media; Cystine; Dietary Supplements; Flour; Glycine max; Homocysteine; Metabolism; Research; Streptomyces; Vitamin B 12; Vitamin B Complex | 1963 |
METHIONINE AND HOMOCYSTEINE AS PROTECTIVE AGENTS AGAINST IRRADIATION DAMAGE.
Topics: Blood Proteins; Body Weight; Brain; Choline; Homocysteine; Methionine; Neoplasms, Radiation-Induced; Neurochemistry; Nucleic Acids; Protective Agents; Proteins; Radiation Protection; Rats; Reproduction; Research | 1964 |
THE INFLUENCE OF ETHIONINE, METHIONINE, CHOLINE, AND RELATED COMPOUNDS ON LIVER GLYCOGEN DEPOSITION IN ADRENALECTOMIZED RATS: RELATION TO THE MODE OF ACTION OF GLUCOCORTICOIDS.
Topics: Adrenalectomy; Choline; Cysteine; Ethionine; Glucocorticoids; Glucose; Homocysteine; Hydrocortisone; Liver; Liver Glycogen; Methionine; Pharmacology; Research; Serine; Tyrosine | 1964 |
STUDIES ON THE FORMATION OF BIOTIN FROM DESTHIOBIOTIN AND SULFATE IN SACCHAROMYCES CEREVISIAE. II. ON SULFUR SOURCES OF BIOTIN FORMATION BY WASHED CELL SUSPENSION OF YEAST.
Topics: Biotin; Choline; Culture Media; Cysteine; Cystine; Ethionine; Glucose; Glutathione; Homocysteine; Metabolism; Methionine; Research; Saccharomyces; Saccharomyces cerevisiae; Sulfates; Sulfur; Sulfur Oxides; Yeast, Dried | 1964 |
VITAMIN B12 AND THE SYNTHESIS OF THE METHYL GROUPS OF CHOLINE IN OCHROMONAS MALHAMENSIS.
Topics: Alkylation; Carbon Isotopes; Choline; Coenzymes; Eukaryota; Formaldehyde; Formates; Homocysteine; Metabolism; Methionine; Ochromonas; Radiometry; Research; Tritium; Vitamin B 12 | 1964 |
Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency.
Topics: Animal Feed; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine beta-Synthase; Cysteine; Female; Heterozygote; Homocysteine; Hyperhomocysteinemia; Lipotropic Agents; Liver; Male; Methionine; Methyltransferases; Mice; Mice, Inbred C57BL; Regression Analysis; Serine | 2004 |
Betaine and folate status as cooperative determinants of plasma homocysteine in humans.
Topics: Adult; Aged; Betaine; Choline; Creatinine; Dose-Response Relationship, Drug; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Sarcosine; Vitamin B 12; Vitamin B 6 | 2005 |
Plasma choline and betaine and their relation to plasma homocysteine in normal pregnancy.
Topics: Adult; Africa, Western; Betaine; Black People; Choline; Dietary Supplements; Female; Folic Acid; Gestational Age; Hematinics; Homocysteine; Humans; Netherlands Antilles; Nutritional Status; Postpartum Period; Predictive Value of Tests; Pregnancy; Regression Analysis | 2005 |
Choline, homocysteine, and pregnancy.
Topics: Animals; Choline; Choline Deficiency; Female; Homocysteine; Humans; Lactation; Maternal Nutritional Physiological Phenomena; Nutritional Requirements; Pregnancy | 2005 |
Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery.
Topics: Betaine; Choline; Chromatography, Liquid; Creatinine; Cross-Sectional Studies; Female; Fetal Blood; Folic Acid; Health Status Indicators; Homocysteine; Humans; Infant, Newborn; Methylation; Oxidation-Reduction; Pregnancy; Regression Analysis; Sarcosine; Vitamin B 12 | 2005 |
Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Betaine; Choline; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Sex Factors; Surveys and Questionnaires; Vitamin B Complex | 2006 |
Effects of chronic betaine ingestion on methionine-loading induced plasma homocysteine elevation in rats.
Topics: Analysis of Variance; Animals; Area Under Curve; Betaine; Betaine-Homocysteine S-Methyltransferase; Carnitine; Choline; Gastrointestinal Agents; Homocysteine; Injections, Intravenous; Liver; Male; Methionine; Rats; Rats, Wistar; Time Factors | 2006 |
Medium-term methionine supplementation increases plasma homocysteine but not ADMA and improves blood pressure control in rats fed a diet rich in protein and adequate in folate and choline.
Topics: Adaptation, Physiological; Animals; Area Under Curve; Arginine; Blood Pressure; Choline; Dietary Proteins; Dietary Supplements; Folic Acid; Homocysteine; Male; Methionine; Methylation; Nitric Oxide; Random Allocation; Rats; Rats, Wistar; Time Factors | 2006 |
Modulation of the homocysteine-betaine relationship by methylenetetrahydrofolate reductase 677 C->t genotypes and B-vitamin status in a large-scale epidemiological study.
Topics: Betaine; Choline; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamins | 2007 |
Choline-related supplements improve abnormal plasma methionine-homocysteine metabolites and glutathione status in children with cystic fibrosis.
Topics: Adolescent; Child; Child, Preschool; Choline; Cystic Fibrosis; Dietary Supplements; Female; Glutathione; Glutathione Disulfide; Homocysteine; Humans; Male; Methionine; Phosphatidylcholines | 2007 |
Prospective study on dietary intakes of folate, betaine, and choline and cardiovascular disease risk in women.
Topics: Aged; Betaine; Cardiovascular Diseases; Choline; Cohort Studies; Diet; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Middle Aged; Netherlands; Nutrition Surveys; Odds Ratio; Postmenopause; Prospective Studies; Surveys and Questionnaires | 2008 |
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women.
Topics: Adult; Alcohol Drinking; Betaine; Biomarkers; Choline; Cross-Sectional Studies; Diet Records; Female; Folic Acid; Homocysteine; Humans; Linear Models; Lipotropic Agents; Methylation; Middle Aged; Predictive Value of Tests; Surveys and Questionnaires; Vitamin B Complex | 2007 |
Is there a new component of the Mediterranean diet that reduces inflammation?
Topics: Betaine; Biomarkers; Choline; Confounding Factors, Epidemiologic; Diet Surveys; DNA Methylation; Epigenesis, Genetic; Feeding Behavior; Female; Greece; Homocysteine; Humans; Inflammation; Life Style; Male; Mediterranean Region; Promoter Regions, Genetic; United States | 2008 |
Dietary choline and betaine intakes in relation to concentrations of inflammatory markers in healthy adults: the ATTICA study.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Betaine; Biomarkers; C-Reactive Protein; Choline; Cross-Sectional Studies; Diet Surveys; Fasting; Feeding Behavior; Female; Greece; Homocysteine; Humans; Inflammation; Interleukin-6; Life Style; Lipotropic Agents; Male; Middle Aged; Tumor Necrosis Factor-alpha | 2008 |
Effects of homocysteine on metabolic pathways in cultured astrocytes.
Topics: Animals; Astrocytes; Brain; Cell Death; Cells, Cultured; Choline; Dose-Response Relationship, Drug; Energy Metabolism; Glucose; Homocysteine; Magnetic Resonance Spectroscopy; Membrane Potential, Mitochondrial; Mitochondria; NADP; Neurodegenerative Diseases; Protein Serine-Threonine Kinases; Pyruvate Carboxylase; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Rats; Rats, Wistar; Taurine | 2008 |
Divergent associations of plasma choline and betaine with components of metabolic syndrome in middle age and elderly men and women.
Topics: Aged; Betaine; Blood Glucose; Blood Pressure; Body Composition; Body Mass Index; Body Weights and Measures; Choline; Exercise; Female; Homocysteine; Humans; Lipids; Male; Metabolic Syndrome; Middle Aged; Triglycerides | 2008 |
Hyperhomocysteinemia induced by guanidinoacetic acid is effectively suppressed by choline and betaine in rats.
Topics: Animals; Betaine; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Glycine; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Rats | 2008 |
Equilibrated diet restores the effects of early age choline-deficient feeding on rat brain antioxidant status and enzyme activities: the role of homocysteine, L-phenylalanine and L-alanine.
Topics: Acetylcholinesterase; Alanine; Animals; Antioxidants; Brain; Brain Chemistry; Ca(2+) Mg(2+)-ATPase; Choline; Diet; Female; Homocysteine; Lecithins; Male; Phenylalanine; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase | 2008 |
Ethnicity and folate influence choline status in young women consuming controlled nutrient intakes.
Topics: Adolescent; Adult; Betaine; Black or African American; Body Mass Index; Choline; Diet; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mexican Americans; Middle Aged; Phosphatidylcholines; Sphingomyelins; White People | 2008 |
Adequate Intake levels of choline are sufficient for preventing elevations in serum markers of liver dysfunction in Mexican American men but are not optimal for minimizing plasma total homocysteine increases after a methionine load.
Topics: Adolescent; Adult; Betaine; Choline; Genotype; Hispanic or Latino; Homocysteine; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Reference Values | 2008 |
Tissue methionine cycle activity and homocysteine metabolism in female rats: impact of dietary methionine and folate plus choline.
Topics: Animals; Body Composition; Choline; Diet; Dietary Proteins; Female; Folic Acid; Homocysteine; Methionine; Models, Biological; Rats; Tissue Distribution | 2009 |
Choline deprivation induces hyperhomocysteinemia in rats fed low methionine diets.
Topics: Animals; Betaine; Choline; Choline Deficiency; Cysteine; Dietary Supplements; Growth; Homocysteine; Hyperhomocysteinemia; Lipotropic Agents; Liver; Male; Methionine; Rats; Rats, Wistar | 2008 |
Genetic variants in phosphatidylethanolamine N-methyltransferase and methylenetetrahydrofolate dehydrogenase influence biomarkers of choline metabolism when folate intake is restricted.
Topics: Adolescent; Adult; Biomarkers; Choline; Dose-Response Relationship, Drug; Female; Folic Acid; Folic Acid Deficiency; Genetic Variation; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Dehydrogenase (NADP); Mexican Americans; Nutritional Status; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Premenopause; Young Adult | 2009 |
Hypohomocysteinemic effect of cysteine is associated with increased plasma cysteine concentration in rats fed diets low in protein and methionine levels.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Caseins; Choline; Cystathionine beta-Synthase; Cysteic Acid; Cysteine; Diet, Protein-Restricted; Dietary Supplements; Glycine; Homocysteine; Hyperhomocysteinemia; Male; Mercaptoethylamines; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; Soybean Proteins | 2009 |
Enhanced one-carbon flux towards DNA methylation: Effect of dietary methyl supplements against gamma-radiation-induced epigenetic modifications.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carbon; Choline; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gamma Rays; Homocysteine; Male; Mice; S-Adenosylmethionine; Time Factors | 2010 |
Methyl donor deficiency affects fetal programming of gastric ghrelin cell organization and function in the rat.
Topics: Animals; Body Weight; Cell Lineage; Choline; Deficiency Diseases; Enteroendocrine Cells; Female; Fetal Development; Folic Acid; Gastric Mucosa; Ghrelin; Growth Hormone; Homocysteine; Immunohistochemistry; Pregnancy; Rats; Rats, Wistar; Vitamin B 12; Weaning | 2010 |
Low dietary choline and low dietary riboflavin during pregnancy influence reproductive outcomes and heart development in mice.
Topics: Animals; Choline; Diet; Female; Fetal Heart; Heart; Heart Defects, Congenital; Homocysteine; Lipotropic Agents; Liver; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Polymorphism, Genetic; Pregnancy; Pregnancy Outcome; Prenatal Nutritional Physiological Phenomena; Riboflavin; Vitamin B Complex | 2010 |
Are dietary choline and betaine intakes determinants of total homocysteine concentration?
Topics: Betaine; Cardiovascular Diseases; Choline; Cognition Disorders; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Vitamin B 12; Vitamin B 6 | 2010 |
Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Carbon; Choline; Diet; Fatty Liver; Female; Ferredoxin-NADP Reductase; Folic Acid; Folic Acid Deficiency; Gene Expression; Homocysteine; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; RNA, Messenger; Sex Factors | 2010 |
Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.
Topics: Amino Acids; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine beta-Synthase; Diet; Enzyme Inhibitors; Glycine N-Methyltransferase; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Brain biochemical correlates of the plasma homocysteine level: a proton magnetic resonance spectroscopy study in the elderly subjects.
Topics: Aged; Aspartic Acid; Basal Ganglia; Brain; Choline; Cobamides; Creatine; Female; Folic Acid; Frontal Lobe; Hippocampus; Homocysteine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Sex Characteristics | 2011 |
Plasma choline concentration varies with different dietary levels of vitamins B6, B12 and folic acid in rats maintained on choline-adequate diets.
Topics: Animals; Biological Availability; Choline; Diet; Dietary Supplements; Folic Acid; Homocysteine; Male; Methylation; Rats; Rats, Sprague-Dawley; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2012 |
Progression of prostate carcinogenesis and dietary methyl donors: temporal dependence.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Choline; Decitabine; Diet; Disease Progression; DNA Methylation; Folic Acid; Homocysteine; Humans; Male; Methionine; Mice; Mice, Nude; Prostatic Neoplasms; Tumor Cells, Cultured; Vitamin B 6 | 2012 |
Methylation capacity in children with severe cerebral palsy.
Topics: Betaine; Biomarkers; Case-Control Studies; Cerebral Palsy; Child; Child, Preschool; Choline; Cystathionine; DNA Methylation; Erythrocyte Indices; Erythrocyte Membrane; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Queensland; Severity of Illness Index; Uric Acid | 2012 |
Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice.
Topics: Aminohydrolases; Animals; Choline; Choline Deficiency; Crosses, Genetic; Disease Models, Animal; Embryo Loss; Female; Fetal Growth Retardation; Folic Acid; Folic Acid Deficiency; Formate-Tetrahydrofolate Ligase; Genes, Lethal; Heterozygote; Homocysteine; Hypoxanthine; Maternal Nutritional Physiological Phenomena; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Mutant Strains; Multienzyme Complexes; Mutagenesis, Insertional; Neural Tube Defects; Pregnancy | 2012 |
Effects of methyl-deficient diets on methionine and homocysteine metabolism in the pregnant rat.
Topics: Animals; Choline; Cysteine; Diet; Female; Fetus; Folic Acid; Homocysteine; Kinetics; Litter Size; Liver; Methionine; Methylation; Pancreas; Phosphorylcholine; Placenta; Pregnancy; Rats; Triglycerides; Weight Gain | 2012 |
Severe methylenetetrahydrofolate reductase deficiency in mice results in behavioral anomalies with morphological and biochemical changes in hippocampus.
Topics: Animals; Apoptosis; Behavior, Animal; Brain; Cerebellum; Choline; Choline O-Acetyltransferase; DNA Methylation; Hippocampus; Homocysteine; Homocystinuria; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Muscle Spasticity; Organ Size; Psychotic Disorders; Receptors, Glucocorticoid | 2012 |
Factors contributing to the resistivity of a higher casein diet against choline deficiency-induced hyperhomocysteinemia in rats.
Topics: Animals; Caseins; Choline; Choline Deficiency; Diet; Glycine; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats; Rats, Wistar; Serine | 2012 |
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 2013 |
Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration.
Topics: Animals; Biomarkers; Choline; Cysteine; Disease Models, Animal; Folic Acid Deficiency; Heterozygote; Homocysteine; Isoenzymes; Liver; Male; Methionine; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutagenesis, Insertional; Mutant Proteins; Random Allocation | 2013 |
Choline status and neurodevelopmental outcomes at 5 years of age in the Seychelles Child Development Nutrition Study.
Topics: Betaine; Child Development; Child, Preschool; Choline; Cognition; Female; Homocysteine; Humans; Language; Linear Models; Longitudinal Studies; Male; Methionine; Neuropsychological Tests; Nutritional Status; Pregnancy; Sarcosine; Seychelles | 2013 |
Betaine supplement alleviates hepatic triglyceride accumulation of apolipoprotein E deficient mice via reducing methylation of peroxisomal proliferator-activated receptor alpha promoter.
Topics: Animals; Apolipoproteins E; Betaine; Carnitine O-Palmitoyltransferase; Choline; Cytochrome P-450 CYP2E1; DNA Methylation; Fatty Acid Synthase, Type I; Food, Formulated; Gene Expression Regulation; Glutathione Peroxidase; Homocysteine; Lipid Metabolism; Lipotropic Agents; Liver; Male; Mice; Mice, Inbred C57BL; PPAR alpha; Promoter Regions, Genetic; Signal Transduction; Superoxide Dismutase; Triglycerides | 2013 |
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult | 2013 |
Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine.
Topics: Adult; Betaine; Choline; Dietary Supplements; Fasting; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Nutritional Status; Pregnancy; Sarcosine; Spain; Vitamin B 12 | 2013 |
Nicotinamide supplementation induces detrimental metabolic and epigenetic changes in developing rats.
Topics: Animals; Betaine; Choline; CpG Islands; Dietary Supplements; DNA; DNA Damage; DNA Methylation; Epigenesis, Genetic; Glucose Intolerance; Homocysteine; Insulin Resistance; Liver; Male; Metabolic Diseases; Niacin; Niacinamide; Oxidative Stress; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Time Factors; Uracil; Vitamin B Complex; Weight Gain | 2013 |
Impact of folic acid fortification on global DNA methylation and one-carbon biomarkers in the Women's Health Initiative Observational Study cohort.
Topics: Aged; Biomarkers; Choline; Cohort Studies; DNA Methylation; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Leukocytes; Middle Aged; Postmenopause | 2014 |
Mouse model for deficiency of methionine synthase reductase exhibits short-term memory impairment and disturbances in brain choline metabolism.
Topics: Acetylcholinesterase; Animals; Apoptosis; Betaine; Cerebellum; Choline; Choline O-Acetyltransferase; Disease Models, Animal; DNA Methylation; Ferredoxin-NADP Reductase; Gene Expression; Hippocampus; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Male; Memory, Short-Term; Methionine; Mice; Mice, Knockout; Synaptic Transmission | 2014 |
Plasma homocysteine, dietary B vitamins, betaine, and choline and risk of peripheral artery disease.
Topics: Adult; Aged; Betaine; Case-Control Studies; Choline; Cohort Studies; Diet; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Peripheral Arterial Disease; Proportional Hazards Models; Riboflavin; Risk Factors; Surveys and Questionnaires; Vitamin B Complex | 2014 |
Increased systolic blood pressure in rat offspring following a maternal low-protein diet is normalized by maternal dietary choline supplementation.
Topics: Animals; Blood Pressure; Body Weight; Choline; Diet, Protein-Restricted; Dietary Supplements; Female; Homocysteine; Male; Maternal Nutritional Physiological Phenomena; Phosphatidylcholines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar | 2012 |
Methyl-donor deficiency in adolescence affects memory and epigenetic status in the mouse hippocampus.
Topics: Age Factors; Animals; Choline; Choline Deficiency; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Folic Acid Deficiency; Hippocampus; Homocysteine; Memory; Methionine; Mice; Mice, Inbred C57BL; Models, Animal; Nutritional Requirements; Promoter Regions, Genetic; Receptors, AMPA; Receptors, Glutamate | 2015 |
[Betaine-enriched beet suppresses hyperhomocysteinemia induced by choline deficiency in rats].
Topics: Amino Acids; Animals; Beta vulgaris; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Choline Deficiency; Cysteine; Diet; Dietary Supplements; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Rats; Rats, Wistar | 2015 |
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Chickens; Choline; Cystathionine gamma-Lyase; Cysteine; Dietary Proteins; Folic Acid; Glycine; Homocysteine; Liver; Male; Meat; Methionine; Rats; Rats, Wistar; Riboflavin; RNA, Messenger; Sarcosine; Serine; Vitamin B 12; Vitamin B 6 | 2015 |
Betaine is as effective as folate at re-synthesizing methionine for protein synthesis during moderate methionine deficiency in piglets.
Topics: Animals; Betaine; Carbon Isotopes; Choline; Cysteine; Diet; Dietary Supplements; Folic Acid; Homocysteine; Methionine; Models, Biological; Oxidation-Reduction; Phenylalanine; Protein Biosynthesis; Swine | 2016 |
Plasma 1-carbon metabolites and academic achievement in 15-yr-old adolescents.
Topics: Adolescent; Betaine; Choline; Cross-Sectional Studies; Educational Status; Female; Genotype; Homocysteine; Humans; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Phosphatidylethanolamine N-Methyltransferase; Polymorphism, Single Nucleotide; Social Class; Surveys and Questionnaires | 2016 |
Multi-Vitamin B Supplementation Reverses Hypoxia-Induced Tau Hyperphosphorylation and Improves Memory Function in Adult Mice.
Topics: Animals; Avoidance Learning; Cerebral Cortex; Choline; Dietary Supplements; Disease Models, Animal; Folic Acid; Glycogen Synthase Kinase 3 beta; Hippocampus; Homocysteine; Hypoxia; Male; Maze Learning; Memory; Memory Disorders; Mice; Phosphorylation; tau Proteins; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2016 |
Comparison of the effects of nicotinic acid and nicotinamide degradation on plasma betaine and choline levels.
Topics: Adult; Betaine; Blood Pressure; Choline; Dietary Supplements; Food, Fortified; Homocysteine; Humans; Hydrolysis; Kinetics; Male; Metanephrine; Methylation; Niacin; Niacinamide; Normetanephrine; Pyridones; Random Allocation; Young Adult | 2017 |
Prospective associations of maternal betaine status with offspring weight and body composition at birth: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort study.
Topics: Adipose Tissue; Adolescent; Adult; Betaine; Birth Weight; Body Composition; Body Mass Index; Choline; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Infant; Linear Models; Male; Methionine; Middle Aged; Nutritional Status; Prospective Studies; Sensitivity and Specificity; Singapore; Vitamin B 12; Young Adult | 2016 |
Choline metabolic pathway gene polymorphisms and risk for Down syndrome: An association study in a population with folate-homocysteine metabolic impairment.
Topics: Adult; Betaine-Homocysteine S-Methyltransferase; Case-Control Studies; Child; Choline; Choline Dehydrogenase; Down Syndrome; Female; Folic Acid; Genetic Association Studies; Genotype; Homocysteine; Humans; Metabolic Networks and Pathways; Mothers; Odds Ratio; Phosphatidylethanolamine N-Methyltransferase; Polymorphism, Single Nucleotide; Risk Factors | 2017 |
Choline and its metabolites are differently associated with cardiometabolic risk factors, history of cardiovascular disease, and MRI-documented cerebrovascular disease in older adults.
Topics: Aged; Aged, 80 and over; Betaine; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Cerebrovascular Disorders; Cholesterol; Choline; Cross-Sectional Studies; Diabetes Mellitus; Female; Homocysteine; Humans; Hypertension; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphatidylcholines; Risk Factors; Triglycerides; Waist Circumference | 2017 |
Oxidative stress and dietary micronutrient deficiencies contribute to overexpression of epigenetically regulated genes by lupus T cells.
Topics: Adult; Aged; Case-Control Studies; CD4-Positive T-Lymphocytes; Choline; Diet; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Female; Flow Cytometry; Folic Acid; Gene Expression Regulation; Homocysteine; Humans; Lupus Erythematosus, Systemic; Male; Methionine; Micronutrients; Middle Aged; Oxidative Stress; Peroxynitrous Acid; Riboflavin; T-Lymphocytes; Vitamin B 12; Vitamin B 6; Young Adult; Zinc | 2018 |
Caloric restriction can affect one-carbon metabolism during pregnancy in the rat: A transgenerational model.
Topics: Animals; Betaine; Caloric Restriction; Carbon; Choline; DNA Methylation; Female; Gene Expression; Homocysteine; Hydrolases; Liver; Male; Methylamines; Models, Biological; Pregnancy; Pregnancy, Animal; Rats, Wistar; S-Adenosylmethionine | 2018 |
Sex differences in hepatic one-carbon metabolism.
Topics: Betaine; Carbon; Choline; Female; Folic Acid; Homocysteine; Humans; Liver; Male; Models, Biological; Sex Characteristics | 2018 |
Maternal choline supplementation ameliorates Alzheimer's disease pathology by reducing brain homocysteine levels across multiple generations.
Topics: Alzheimer Disease; Animals; Brain; Choline; Dietary Supplements; Disease Models, Animal; Female; Homocysteine; Male; Mice; Mice, Transgenic | 2020 |
Evaluating the therapeutic potential of one-carbon donors in nonalcoholic fatty liver disease.
Topics: Animals; Betaine; Carbon; Choline; Diet, High-Fat; Dietary Supplements; DNA Methylation; Folic Acid; Glutathione; Homocysteine; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; S-Adenosylmethionine | 2019 |
Total Methionine Restriction Treatment of Cancer.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Choline; Homocysteine; Humans; Liver; Methionine; Mice, Nude; Neoplasms; Temozolomide; Xenograft Model Antitumor Assays | 2019 |
Maternal betaine status, but not that of choline or methionine, is inversely associated with infant birth weight.
Topics: Adult; Betaine; Birth Weight; Choline; Female; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Male; Maternal Nutritional Physiological Phenomena; Methionine; Pregnancy; Pregnancy Trimesters; Sarcosine | 2019 |
Associations between folate and choline intake, homocysteine metabolism, and genetic polymorphism of MTHFR, BHMT and PEMT in healthy pregnant Polish women.
Topics: Adolescent; Adult; Betaine-Homocysteine S-Methyltransferase; Choline; Female; Folic Acid; Genotype; Glutathione; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Phosphatidylethanolamine N-Methyltransferase; Poland; Polymorphism, Genetic; Pregnancy; Pregnancy Trimester, Third; Young Adult | 2020 |
A novel approach in the management of hyperhomocysteinemia.
Topics: Alcohol Oxidoreductases; Animals; Choline; Cytidine Diphosphate Choline; Dietary Supplements; Endothelial Cells; Folic Acid; Homocysteine; Humans; Hydrolysis; Hyperhomocysteinemia; Kidney; Life Style; Liver; Methionine; Models, Theoretical; Vitamin B 12; Vitamin B 6 | 2019 |
Lower plasma glutathione, choline, and betaine concentrations are associated with fatty liver in postmenopausal women.
Topics: Betaine; Biomarkers; Choline; Fatty Liver; Female; Folic Acid; Glutathione; Homocysteine; Humans; Postmenopause | 2022 |
Nutritional biomarkers and heart failure requiring hospitalization in patients with type 2 diabetes: the SURDIAGENE cohort.
Topics: Aged; Betaine; Biomarkers; Carnitine; Choline; Cohort Studies; Cysteine; Diabetes Mellitus, Type 2; Female; Heart Failure; Homocysteine; Hospitalization; Humans; Male; Methionine; Middle Aged; Prospective Studies; Risk Factors | 2022 |
Profiling of Homocysteine Metabolic Pathway Related Metabolites in Plasma of Diabetic Mellitus Based on LC-QTOF-MS.
Topics: Choline; Cysteine; Diabetes Mellitus; Homocysteine; Humans; Metabolic Networks and Pathways; Methionine; Racemethionine; Taurine | 2023 |
[Association between maternal plasma one-carbon biomarkers during pregnancy and fetal growth in twin pregnancies].
Topics: Adult; Betaine; Biomarkers; Birth Weight; Choline; Cohort Studies; Female; Fetal Development; Fetal Weight; Homocysteine; Humans; Infant, Newborn; Methionine; Pregnancy; Pregnancy Outcome; Pregnancy Trimesters; Pregnancy, Twin | 2023 |