homocysteine and choline

homocysteine has been researched along with choline in 151 studies

Research

Studies (151)

TimeframeStudies, this research(%)All Research%
pre-199035 (23.18)18.7374
1990's10 (6.62)18.2507
2000's42 (27.81)29.6817
2010's53 (35.10)24.3611
2020's11 (7.28)2.80

Authors

AuthorsStudies
Bolondi, L; Caletti, GC; Fontana, G; Ventrucci, M1
Canfield, CJ; McCormick, GJ; Smith, CC1
Labadie, P1
Baker, DH; Harter, JM1
Hieb, WF; Lu, NC; Stokstad, EL1
Olszewski, AJ1
Baker, DH; Czarnecki, GL1
Vance, DE; Yao, ZM1
Lehmann, J; Tsai, C; Wood, PL1
Bialkowska, M; McCully, KS; Olszewski, AJ; Rudnicki, S; Szostak, WB1
Finkelstein, JD; Harris, BJ; Martin, JJ1
Barak, AJ; Beckenhauer, HC; Tuma, DJ1
Cheah, KS; Watkins, JC1
Capitolo, S; Marchioni, GF; Mariani, B1
Amata, D; Gaggi, R1
Bandini, S; Monteforte, S1
Azzena, D1
Batra, KK; Buehring, KU; Stokstad, EL1
Rocca, F1
Bonini, M1
Demain, AL; White, RF1
Del Mastro, S; Gaggi, R1
Khairallah, EA; Wolf, G1
Daniel, LJ; Lust, G2
Guttman, HN1
Ebert, MH; Mudd, SH; Scriver, CR1
Hoffman, RM1
Barak, AJ; Tuma, DJ1
da Costa, KA; Kim, YI; Mason, JB; Miller, JW; Nadeau, M; Selhub, J; Smith, D; Zeisel, SH1
Henning, SM; Jacob, RA; Swendseid, ME; Wu, MM1
Pérez de Miguelsanz, J; Ragel, C; Varela-Moreiras, G1
Baker, DH; Emmert, JL; Garrow, TA1
Connell, A; Lobley, GE; Revell, D1
Canty, DJ1
Bottiglieri, T; Charles, HC; Gray, L; Hyland, K; Jaeken, J; Kahler, SG; Lazeyras, F; Van Hove, JL; Zeisel, SH1
Glade, MJ1
Allman-Farinelli, MA; Jacob, RA; Jenden, DJ; Swendseid, ME1
Incharoensakdi, A; Waditee, R1
Hirosawa, K; Hishida, A; Ikegaya, N; Katoh, S; Kimura, M; Kumagai, H1
Kokkinakis, DM; Wick, JB; Zhou, QX1
Castro, C; Chen, Z; Garrow, T; Genest, J; Laryea, MD; Lussier-Cacan, S; Mar, MH; Rozen, R; Schwahn, BC; Wendel, U; Zeisel, SH1
Kacprzak, MM; Lewandowska, I; Matthews, RG; Paszewski, A1
ALEXANDER, GJ1
FIEDLER, E; GUELZOW, M1
CRAWFORD, JM; CURTIS, DR; VOORHOEVE, PE; WILSON, VJ1
VALENCIA, R1
EDWARDS, CH; EDWARDS, GA; GADSEN, EL1
KORITZ, SB; MUNCK, A1
NIMURA, T; SAHASHI, Y; SUZUKI, T1
Bleie, Ø; Holm, PI; Lien, EA; Nordrehaug, JE; Nygård, O; Refsum, H; Ueland, PM1
Castro, C; Garrow, TA; Leclerc, D; Lussier-Cacan, S; Mar, MH; Rozen, R; Schwahn, BC; Wendel, U; Zeisel, SH1
Blom, HJ; den Heijer, M; Holm, PI; Keijzer, MB; Midttun, Ø; Ueland, PM; Vollset, SE1
Zeisel, SH3
da Costa, KA; Fischer, LM; Gaffney, CE; Zeisel, SH1
Olthof, MR; Verhoef, P1
Clarke, R; Holm, PI; Melse-Boonstra, A; Olthof, M; Ueland, PM; Verhoef, P1
Fokkema, MR; Holm, PI; Muskiet, FA; Ueland, PM; van der Dijs, FP; Velzing-Aarts, FV1
Brink, EJ; Katan, MB; Olthof, MR; Verhoef, P1
Brody, LC; Conley, M; Cox, C; Daly, SF; Kirke, PN; Mills, JL; Molloy, AM; Scott, JM; Ueland, PM1
Beers, KW; Blair, ME; Emmert, JL; Fanatico, AC; Pillai, PB1
Cho, E; Colditz, GA; Dougherty, L; Jacques, P; Selhub, J; Willett, WC; Zeisel, SH1
Maloney, CA; Rees, WD; Wilson, FA1
Nakata, R; Shigematsuo, N; Yagisawa, M1
Blair, ME; Emmert, JL; Fanatico, AC; Pillai, PB1
Blouet, C; Daré, S; Hammiche, A; Huneau, JF; Mariotti, F; Tomé, D1
Grotmol, T; Holm, PI; Hustad, S; Schneede, J; Ueland, PM; Vollset, SE1
Davidson, AG; Innis, SM; James, SJ; Melynk, S1
Bots, ML; Dalmeijer, GW; Olthof, MR; van der Schouw, YT; Verhoef, P1
Blom, HJ; Clarke, R; de Groot, LC; Eussen, SJ; Hoefnagels, WH; Ueland, PM; van Staveren, WA1
Chiuve, SE; Dougherty, LW; Giovannucci, EL; Hankinson, SE; Rimm, EB; Willett, WC; Zeisel, SH1
Li, Z; Vance, DE1
Antonopoulou, S; Detopoulou, P; Panagiotakos, DB; Pitsavos, C; Stefanadis, C1
Atkinson, W; Chambers, ST; Elmslie, J; George, PM; Lever, M1
Brennan, L; Jin, Y1
Bleie, Ø; Konstantinova, SV; Nygård, O; Tell, GS; Ueland, PM; Vollset, SE1
Morita, T; Ohuchi, S; Setoue, M; Sugiyama, K2
Carageorgiou, H; Feskou, I; Galanopoulou, P; Liapi, C; Tsakiris, S; Zarros, A1
Abratte, CM; Caudill, MA; Hung, J; Li, R; Moriarty, DJ; Wang, W1
Abratte, CM; Caudill, MA; Li, R; Maletz, CV; Solis, C; Veenema, K; Wang, W1
Calder, AG; Holtrop, G; Lobley, GE; O'Kennedy, N; Rees, WD; van den Borne, JJ; Wilson, FA1
Caudill, MA; Hinkis, S; Ivanov, A; Nash-Barboza, S1
Atkinson, W; Chambers, ST; Elmslie, J; George, PM; Lever, M; Slow, S1
Kawakami, Y; Morita, T; Ohuchi, S; Sugiyama, K1
Batra, V; Devasagayam, TP; Sridhar, S1
Audonnet, S; Beck, B; Blaise, S; Bossenmeyer-Pourié, C; Daval, JL; Guéant, JL; Koziel, V; Ortiou, S; Pourié, G; Rio, MC; Tomasetto, C1
Caudill, MA; Chan, J; Deng, L; Mikael, LG; Pickell, L; Rozen, R; Wu, Q; Yan, J1
Cho, E; Dougherty, L; Giovannucci, E; Jacques, PF; Lee, JE; Selhub, J; Zeisel, SH1
Caudill, MA; Christensen, KE; Deng, L; Rozen, R; Wang, X; Wu, Q1
Garrow, TA; Gupta, S; Jiracek, J; Kruger, WD; Li, L; Rozen, R; Schalinske, KL; Strakova, J; Williams, KT1
Caudill, MA; West, AA1
Chen, CS; Juo, SH; Ko, CH; Kuo, YT; Lee, CC; Li, CW; Lin, HF; Liu, GC; Tsai, HY; Yeh, YC; Yen, CF1
Böhlke, M; Broersen, LM; Hageman, RJ; Kamphuis, PJ; Maher, TJ; van Wijk, N; Watkins, CJ; Wurtman, RJ1
Carducci, MA; Herman, JG; Shabbeer, S; Simons, BW; Williams, SA1
Bonham, MP; Duffy, ME; McCormack, JM; McNulty, H; Molloy, AM; Robson, PJ; Scott, JM; Strain, JJ; Ueland, PM; Wallace, JM; Walsh, PM; Ward, M1
Boyd, RN; Davies, PS; Moxon-Lester, L; Obeid, R; Schoendorfer, NC; Sharp, N; Vitetta, L1
Allen, RH; Beaudin, AE; Perry, CA; Stabler, SP; Stover, PJ1
Anderson, SE; Calder, AG; Holtrop, G; Lobley, GE; Rees, WD; Wilson, FA1
Bedell, BJ; Caudill, MA; Deng, L; Jadavji, NM; Leclerc, D; Malysheva, O; Rozen, R1
Liu, Y; Liu, YQ; Mori, M; Morita, T; Sugiyama, K1
Caudill, M; Jiang, X; Mikael, LG; Pancer, J; Rozen, R; Wu, Q1
Abarinov, EV; Allen, RH; Ash, JA; Caudill, MA; Field, MS; Malysheva, OV; Shields, KS; Stabler, SP; Stover, PJ; Strupp, BJ1
Bonham, MP; Davidson, PW; Henderson, J; Kobrosly, RW; McAfee, AJ; McSorley, EM; Mulhern, MS; Myers, GJ; Shamlaye, CF; Strain, JJ; Thurston, SW; Ueland, PM; van Wijngaarden, E; Wallace, JM; Watson, GE1
Chang, Y; Chen, L; Jin, T; Tan, Y; Wang, L; Wei, J; Zhu, H1
Cole, D; Cox, SE; da Costa, KA; Dominguez-Salas, P; Dyer, RA; Fulford, AJ; Hennig, BJ; Innis, SM; Moore, SE; Prentice, AM; Waterland, RA; Zeisel, SH1
Ballesteros, M; Berrocal-Zaragoza, MI; Cavallé-Busquets, P; Fernandez-Ballart, JD; Fernàndez-Roig, S; Murphy, MM; Salat-Batlle, J; Ueland, PM1
Cao, JM; Cao, Y; Gong, XJ; Guo, J; Guo, M; Li, D; Lun, YZ; Luo, N; Sun, WP; Tian, YJ; Zhou, SS1
Ali, NS; Michels, KB; Osterhues, A1
Obeid, R1
Benoist, JF; Blom, HJ; Imbard, A1
Bae, S; Bailey, LB; Beresford, SA; Brown, EC; Buck, K; Caudill, MA; Cheng, TY; Hou, L; Malysheva, O; Maneval, DR; Miller, JW; Neuhouser, ML; Song, X; Ulrich, CM; Xiao, L; Zheng, Y1
Bahous, RH; Bedell, BJ; Caudill, MA; Deng, L; Grand'maison, M; Jadavji, NM; Malysheva, O; Rozen, R1
Bandeira, IC; Blom, HJ; Castro, K; D'Almeida, V; de Souza, CF; Imbard, A; Leistner-Segal, S; Nalin, T; Poloni, S; Schwartz, IV; Spritzer, PM; Tonon, T1
Bertoia, ML; Cooke, JP; Joosten, MM; Mittleman, MA; Mukamal, KJ; Pai, JK; Rimm, EB1
Chambers, ST; Elmslie, JL; George, PM; Krebs, JD; Lever, M; Lunt, H; McEntyre, CJ; Parry-Strong, A; Slow, S1
Bai, SY; Briggs, DI; Vickers, MH1
Ishii, D; Kawai, K; Mashimo, Y; Matsuda, S; Matsuzawa, D; Shimizu, E; Sutoh, C; Tomizawa, H1
Allen, RH; Bae, S; Caudill, MA; Jiang, X; Malysheva, O; Perry, CA; Stabler, SP; West, AA; Yan, J1
Han, F; Huang, Z; Liu, Y; Lu, J; Sugiyama, K; Sun, L; Wang, Q1
Berge, RK; Bjørndal, B; Lysne, V; Nordrehaug, JE; Nygård, O; Skorve, J; Vik, R1
Bertolo, RF; Brunton, JA; Harding, SV; McBreairty, LE; Randell, EW; Robinson, JL1
Herrmann, W; Hurtig-Wennlöf, A; Nilsson, TK; Obeid, R; Owen, JR; Sjöström, M; Zeisel, S1
Alshaikh, B; Bennett, MJ; Maqbool, A; Mascarenhas, M; Schall, JI; Stallings, VA1
Chen, Y; Hong, Y; Wang, W; Xiao, Z; Yu, L1
Chen, NN; Guo, M; Li, D; Sun, WP; Zhai, MZ; Zhou, SS; Zhou, Y1
Aris, IM; Chong, MF; Chong, YS; Fortier, MV; Gluckman, PD; Godfrey, KM; Kramer, MS; Lee, YS; Quah, PL; Saw, SM; Tint, MT; van Lee, L; Yap, FK1
Chauhan, A; Jaiswal, SK; Kumar, A; Lakhotia, AR; Rai, AK; Sukla, KK1
Bhadelia, RA; Johnson, EJ; Lichtenstein, AH; Roe, AJ; Rogers, GT; Rosenberg, IH; Scott, TM; Smith, CE; Zeisel, SH; Zhang, S1
Che, L; Chen, Y; Fang, Z; Feng, B; Li, J; Lin, Y; Liu, H; Mou, D; Wang, J; Xu, S1
Ray, D; Richardson, BC; Strickland, FM1
Chmurzynska, A; Malinowska, AM; Mlodzik, MA; Nowacka-Woszuk, J; Radziejewska, A; Szwengiel, A1
Dahdoul, T; Nijhout, HF; Reed, MC; Sadre-Marandi, F1
Caccamo, A; Dave, N; Ferreira, E; Huentelman, MJ; Naymik, M; Oddo, S; Piras, IS; Tran, A; Velazquez, R; Winslow, W1
Ali, MA; Bakir, MB; Kamel, MA; Khalifa, EA; Refaat, R; Salama, MA1
Frenkel, EP; Hoffman, RM; Kokkinakis, DM1
Cheng, ZY; Du, YF; Shi, HF; Wang, XL; Wei, Y; Wu, TC; Yang, J; Zuo, XF1
Barlik, M; Chmurzynska, A; Drews, K; KurzawiŃska, G; Malinowska, AM; Radziejewska, A; Różycka, A; Seremak-Mrozikiewicz, A; Wolski, H1
Goyal, A; Gupta, JK; Narayan Yadav, H; Qureshi, SS1
Bae, S; Caudill, MA; Jiang, X; King, JH; Klatt, KC; Kwan, STC; Malysheva, OV; Roberson, MS; Yan, J1
Bozack, AK; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Parvez, F; Shahriar, H; Siddique, AB; Slavkovich, V; Uddin, MN1
Elango, R1
Andraos, S; Cameron-Smith, D; Chia, PHP; D'Souza, RF; Gillies, NA; Knowles, SO; Milan, AM; Mitchell, CJ; Mitchell, SM; Ramzan, F; Roy, NC; Sharma, P; Sjödin, A; Wagner, KH; Zeng, N1
Cameron-Smith, D; Franzke, B; Gillies, NA; Hofmann, M; Milan, AM; Oesen, S; Roy, NC; Schober-Halper, B; Strasser, EM; Tosevska, A; Wagner, KH; Wessner, B1
Chmurzynska, A; Muzsik-Kazimierska, A; Nikrandt, G; Szwengiel, A1
Cariou, B; Croyal, M; Gand, E; Goronflot, T; Hadjadj, S; Jacobi, D; Le May, C; Prieur, X; Ragot, S; Saulnier, PJ; Trochu, JN; Wargny, M1
Arthurs, AL; Jankovic-Karasoulos, T; Roberts, CT; Smith, MD; Williamson, JM1
Li, C; Liu, W; Lv, B; Qin, J; Xue, J; Xue, Z; Yi, N1
Du, YF; Gong, XL; Shi, HF; Wang, XL; Wei, Y; Wu, TC; Zhao, YY1

Reviews

12 review(s) available for homocysteine and choline

ArticleYear
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
    Biochimica et biophysica acta, 1984, Volume: 738, Issue:1-2

    Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40

1984
Betaine, metabolic by-product or vital methylating agent?
    Life sciences, 1983, Feb-14, Volume: 32, Issue:7

    Topics: Alcohol Oxidoreductases; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Diet; Ethanol; Homocysteine; Humans; Liver; Methionine; Methotrexate; Methylation; Methyltransferases; Oxidation-Reduction; Rats; Tetrahydrofolates

1983
Nutritional importance of choline for brain development.
    Journal of the American College of Nutrition, 2004, Volume: 23, Issue:6 Suppl

    Topics: Animals; Apoptosis; Brain; Cell Division; Cell Movement; Cell Proliferation; Choline; Female; Folic Acid; Gene Expression Regulation, Developmental; Homocysteine; Humans; Male; Memory; Neurons; Pregnancy

2004
Effects of betaine intake on plasma homocysteine concentrations and consequences for health.
    Current drug metabolism, 2005, Volume: 6, Issue:1

    Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Folic Acid; Homocysteine; Humans; Lipids

2005
Sulfur amino acid metabolism in pregnancy: the impact of methionine in the maternal diet.
    The Journal of nutrition, 2006, Volume: 136, Issue:6 Suppl

    Topics: Amino Acids, Sulfur; Animals; Choline; Diet; DNA Methylation; Drug Interactions; Endocrine System; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Methylation; Nutritional Requirements; Pregnancy; Proteins; S-Adenosylmethionine

2006
Phosphatidylcholine and choline homeostasis.
    Journal of lipid research, 2008, Volume: 49, Issue:6

    Topics: Animals; Cholesterol, VLDL; Choline; Homeostasis; Homocysteine; Humans; Mice; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase

2008
Genetic variation: impact on folate (and choline) bioefficacy.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2010, Volume: 80, Issue:4-5

    Topics: Biological Availability; Choline; Epistasis, Genetic; Folic Acid; Genetic Variation; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2)

2010
The role of folic acid fortification in neural tube defects: a review.
    Critical reviews in food science and nutrition, 2013, Volume: 53, Issue:11

    Topics: Biological Availability; Choline; Edible Grain; Female; Folic Acid; Folic Acid Antagonists; Food, Fortified; Homocysteine; Humans; Neural Tube Defects; Nutritional Requirements; Pregnancy; Recommended Dietary Allowances; United States; Vitamin B 12

2013
The metabolic burden of methyl donor deficiency with focus on the betaine homocysteine methyltransferase pathway.
    Nutrients, 2013, Sep-09, Volume: 5, Issue:9

    Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Dietary Supplements; Disease Models, Animal; DNA Methylation; Fasting; Fatty Liver; Folic Acid; Homocysteine; Humans; Liver; Metabolic Networks and Pathways; Methionine; Muscular Diseases; S-Adenosylmethionine

2013
Neural tube defects, folic acid and methylation.
    International journal of environmental research and public health, 2013, Sep-17, Volume: 10, Issue:9

    Topics: Animals; Choline; Folic Acid; Homocysteine; Humans; Methylation; Neural Tube Defects; Neurulation; Vitamin B 12; Vitamin B Complex

2013
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
    The Journal of nutrition, 2020, 10-01, Volume: 150, Issue:Suppl 1

    Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur

2020
High Folate, Perturbed One-Carbon Metabolism and Gestational Diabetes Mellitus.
    Nutrients, 2022, Sep-22, Volume: 14, Issue:19

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Carbon; Choline; Diabetes, Gestational; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Micronutrients; Neural Tube Defects; Pregnancy; Thymidylate Synthase; Vitamin B 12

2022

Trials

23 trial(s) available for homocysteine and choline

ArticleYear
[Therapeutic effect of a pharmacologic combination of choleretics and digestive enzymes in exocrine pancreatic insufficiency].
    Minerva medica, 1975, Mar-07, Volume: 66, Issue:17

    Topics: Adolescent; Adult; Aged; Amylases; Celiac Disease; Cholagogues and Choleretics; Choline; Clinical Trials as Topic; Crohn Disease; Drug Combinations; Drug Evaluation; Female; Gastroenteritis; Homocysteine; Humans; Male; Middle Aged; Pancreatic Neoplasms; Pancreatitis; Pronase; Silicone Elastomers; Vitamin B 12; Whipple Disease

1975
[Treatment of liver damage during a course of tuberculosis and chronic pulmonary diseases. Necessity of treatment and new trends].
    Minerva medica, 1974, Aug-04, Volume: 65, Issue:57

    Topics: Bilirubin; Choline; Chronic Disease; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Female; Homocysteine; Humans; Lactones; Liver; Liver Diseases; Liver Function Tests; Lung Diseases; Male; Peritonitis; Pleurisy; Silicotuberculosis; Transaminases; Tuberculosis, Pulmonary; Vitamin B 12

1974
[Controlled clinical trial of a new combination of phosphorylcholine, homocysteine-gamma-thiolactone and vitamin B 12 in the parenteral treatment of chronic hepatopathies].
    La Clinica terapeutica, 1974, Jun-30, Volume: 69, Issue:6

    Topics: Adult; Aged; Choline; Chronic Disease; Drug Combinations; Evaluation Studies as Topic; Female; Homocysteine; Humans; Lactones; Liver Diseases; Liver Function Tests; Male; Middle Aged; Phosphoric Acids; Vitamin B 12

1974
Folate nutriture alters choline status of women and men fed low choline diets.
    The Journal of nutrition, 1999, Volume: 129, Issue:3

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Choline; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipids; Male; Methionine; Methylation; Middle Aged; Nutritional Physiological Phenomena; Nutritional Status; Phosphatidylcholines; Reference Values; S-Adenosylmethionine

1999
Betaine as a determinant of postmethionine load total plasma homocysteine before and after B-vitamin supplementation.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:2

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Betaine; Choline; Coronary Angiography; Dietary Supplements; Drug Administration Schedule; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Methionine; Methyltransferases; Middle Aged; Sarcosine; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2004
Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load.
    The American journal of clinical nutrition, 2005, Volume: 81, Issue:2

    Topics: Adult; Analysis of Variance; Animals; Choline; Choline Deficiency; Cross-Over Studies; Homocysteine; Humans; Lipotropic Agents; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Middle Aged; Nutritional Status; Pilot Projects

2005
Betaine concentration as a determinant of fasting total homocysteine concentrations and the effect of folic acid supplementation on betaine concentrations.
    The American journal of clinical nutrition, 2005, Volume: 81, Issue:6

    Topics: Administration, Oral; Aged; Betaine; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged

2005
Choline supplemented as phosphatidylcholine decreases fasting and postmethionine-loading plasma homocysteine concentrations in healthy men.
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:1

    Topics: Administration, Oral; Choline; Cross-Sectional Studies; Double-Blind Method; Fasting; Homocysteine; Humans; Kidney; Liver; Male; Methionine; Middle Aged; Phosphatidylcholines

2005
Homocysteine remethylation in young broilers fed varying levels of methionine, choline, and betaine.
    Poultry science, 2006, Volume: 85, Issue:1

    Topics: Animals; Betaine; Chickens; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Homocysteine; Methionine; Methylation

2006
Homocysteine remethylation in broilers fed surfeit choline or betaine and varying levels and sources of methionine from eight to twenty-two days of age.
    Poultry science, 2006, Volume: 85, Issue:10

    Topics: Aging; Animal Feed; Animals; Betaine; Chickens; Choline; Dose-Response Relationship, Drug; Homocysteine; Methionine; Methylation

2006
The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people.
    The British journal of nutrition, 2007, Volume: 98, Issue:5

    Topics: Aged; Attention; Betaine; Choline; Cognition; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Memory; Neuropsychological Tests; Psychomotor Performance; Sarcosine; Vitamin B 12; Vitamin B Complex

2007
Dietary and supplementary betaine: acute effects on plasma betaine and homocysteine concentrations under standard and postmethionine load conditions in healthy male subjects.
    The American journal of clinical nutrition, 2008, Volume: 87, Issue:3

    Topics: Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Betaine; Choline; Cross-Over Studies; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Homocysteine; Humans; Male; Methionine; Sarcosine; Statistics, Nonparametric

2008
Dietary and supplementary betaine: effects on betaine and homocysteine concentrations in males.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2009, Volume: 19, Issue:11

    Topics: Adult; Betaine; Biomarkers; Choline; Creatinine; Cross-Over Studies; Diet; Dietary Supplements; Folic Acid; Homocysteine; Humans; Lipids; Male; Sarcosine; Time Factors; Vitamin B 12; Young Adult

2009
Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women.
    The British journal of nutrition, 2012, Volume: 108, Issue:7

    Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Northern Ireland; Nutritional Status; Patient Compliance; Postmenopause

2012
Body composition in patients with classical homocystinuria: body mass relates to homocysteine and choline metabolism.
    Gene, 2014, Aug-10, Volume: 546, Issue:2

    Topics: Adiposity; Adolescent; Adult; Amino Acids; Bone Density; Cholesterol, HDL; Choline; Ethanolamine; Female; Homocysteine; Homocystinuria; Humans; Male

2014
Extreme urinary betaine losses in type 2 diabetes combined with bezafibrate treatment are associated with losses of dimethylglycine and choline but not with increased losses of other osmolytes.
    Cardiovascular drugs and therapy, 2014, Volume: 28, Issue:5

    Topics: Adult; Aged; Betaine; Bezafibrate; Choline; Diabetes Mellitus, Type 2; Female; Glycerylphosphorylcholine; Homocysteine; Humans; Hypolipidemic Agents; Inositol; Male; Middle Aged; Sarcosine; Taurine; Young Adult

2014
Vitamin B-12 Status Differs among Pregnant, Lactating, and Control Women with Equivalent Nutrient Intakes.
    The Journal of nutrition, 2015, Volume: 145, Issue:7

    Topics: Adult; Biomarkers; Breast Feeding; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Energy Intake; Female; Healthy Volunteers; Homocysteine; Humans; Lactation; Methylmalonic Acid; Micronutrients; Postpartum Period; Pregnancy; Recommended Dietary Allowances; Vitamin B 12; Young Adult

2015
Choline supplementation alters some amino acid concentrations with no change in homocysteine in children with cystic fibrosis and pancreatic insufficiency.
    Nutrition research (New York, N.Y.), 2016, Volume: 36, Issue:5

    Topics: Adolescent; Amino Acids; Amino Acids, Branched-Chain; Child; Child, Preschool; Choline; Cystic Fibrosis; Dietary Supplements; Exocrine Pancreatic Insufficiency; Female; Homocysteine; Humans; Male; Methionine; Placebos

2016
Maternal methyl donor supplementation during gestation counteracts bisphenol A-induced oxidative stress in sows and offspring.
    Nutrition (Burbank, Los Angeles County, Calif.), 2018, Volume: 45

    Topics: Actins; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Benzhydryl Compounds; Betaine; Catalase; Choline; Diet; Dietary Supplements; Female; Folic Acid; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Homocysteine; Malondialdehyde; Maternal Nutritional Physiological Phenomena; Oxidative Stress; Phenols; Placenta; Pregnancy; Superoxide Dismutase; Swine; Vitamin B 12

2018
Maternal choline supplementation alters vitamin B-12 status in human and murine pregnancy.
    The Journal of nutritional biochemistry, 2019, Volume: 72

    Topics: Adult; Animals; Betaine-Homocysteine S-Methyltransferase; Choline; Choline Dehydrogenase; Dietary Supplements; Female; Gene Expression Regulation; Homeodomain Proteins; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methylmalonic Acid; Mice, Mutant Strains; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Trimester, Third; Transcription Factors; Vitamin B 12; Young Adult

2019
Betaine and choline status modify the effects of folic acid and creatine supplementation on arsenic methylation in a randomized controlled trial of Bangladeshi adults.
    European journal of nutrition, 2021, Volume: 60, Issue:4

    Topics: Adult; Arsenic; Betaine; Choline; Creatine; Dietary Supplements; Environmental Exposure; Folic Acid; Homocysteine; Humans; Methylation

2021
Responsiveness of one-carbon metabolites to a high-protein diet in older men: Results from a 10-wk randomized controlled trial.
    Nutrition (Burbank, Los Angeles County, Calif.), 2021, Volume: 89

    Topics: Aged; Betaine; Carbon; Choline; Diet; Diet, High-Protein; Folic Acid; Homocysteine; Humans; Male; Vitamin B Complex

2021
Nutritional supplementation alters associations between one-carbon metabolites and cardiometabolic risk profiles in older adults: a secondary analysis of the Vienna Active Ageing Study.
    European journal of nutrition, 2022, Volume: 61, Issue:1

    Topics: Aged; Aging; Betaine; Carbon; Cardiovascular Diseases; Choline; Dietary Supplements; Female; Homocysteine; Humans; Male

2022

Other Studies

116 other study(ies) available for homocysteine and choline

ArticleYear
Plasmodium knowlesi: in vitro biosynthesis of methionine and thymidylic acid.
    Experimental parasitology, 1977, Volume: 43, Issue:1

    Topics: Animals; Betaine; Cells, Cultured; Choline; Erythrocytes; Folic Acid; Formaldehyde; Formyltetrahydrofolates; Haplorhini; Histidine; Homocysteine; Macaca mulatta; Methionine; Plasmodium; Sarcosine; Serine; Thymidine Monophosphate; Thymine Nucleotides

1977
[Methyls of biological importance].
    La Revue du praticien, 1979, Jun-11, Volume: 29, Issue:33

    Topics: Betaine; Carnitine; Choline; Dealkylation; Homocysteine; Humans; Lipid Metabolism; Methane; Methionine; Methylation; Phosphatidylcholines

1979
Sulfur amino acid activity of D- and L-homocystein for chicks.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 157, Issue:1

    Topics: Animals; Chickens; Choline; Cysteine; Diet; Female; Homocysteine; Isomerism; Male; Methionine

1978
Effect of vitamin B12 and folate on biosynthesis of methionine from homocysteine in the nematode Caenorhabditis briggsae.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1976, Volume: 151, Issue:4

    Topics: Animals; Choline; Folic Acid; Homocysteine; Methionine; Nematoda; Vitamin B 12

1976
Homocysteine content of plasma in ischemic heart disease, the reducing effect of pyridoxine, folate, cobalamin, choline, riboflavin and troxerutin. Correction of a calculation error.
    Atherosclerosis, 1991, Volume: 88, Issue:1

    Topics: Amino Acids; Anticoagulants; Choline; Coronary Disease; Folic Acid; Homocysteine; Humans; Hydroxyethylrutoside; Pyridoxine; Riboflavin; Vitamin B 12

1991
Transmethylation of homocysteine to methionine: efficiency in the rat and chick.
    The Journal of nutrition, 1985, Volume: 115, Issue:10

    Topics: Animals; Betaine; Body Weight; Chickens; Choline; Diet; Homocysteine; Male; Methionine; Methylation; Rats; Rats, Inbred Strains; Sarcosine; Tetrahydrofolates

1985
Head group specificity in the requirement of phosphatidylcholine biosynthesis for very low density lipoprotein secretion from cultured hepatocytes.
    The Journal of biological chemistry, 1989, Jul-05, Volume: 264, Issue:19

    Topics: Animals; Apolipoproteins; Betaine; Cells, Cultured; Choline; Chromatography, High Pressure Liquid; Deanol; Ethanolamine; Ethanolamines; Homocysteine; Lipoproteins; Lipoproteins, VLDL; Liver; Male; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; Triglycerides

1989
Homocysteic acid as a putative excitatory amino acid neurotransmitter: I. Postsynaptic characteristics at N-methyl-D-aspartate-type receptors on striatal cholinergic interneurons.
    Journal of neurochemistry, 1988, Volume: 51, Issue:6

    Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Animals; Choline; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; Homocysteine; Interneurons; Magnesium; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereoisomerism; Tachyphylaxis; Tiletamine

1988
Reduction of plasma lipid and homocysteine levels by pyridoxine, folate, cobalamin, choline, riboflavin, and troxerutin in atherosclerosis.
    Atherosclerosis, 1989, Volume: 75, Issue:1

    Topics: Adult; Anticoagulants; Choline; Coronary Artery Disease; Coronary Disease; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hydroxyethylrutoside; Lipids; Male; Middle Aged; Pyridoxine; Riboflavin; Vitamin B 12

1989
Methionine metabolism in mammals. The methionine-sparing effect of cystine.
    The Journal of biological chemistry, 1988, Aug-25, Volume: 263, Issue:24

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine; Cystathionine beta-Synthase; Cystine; Diet; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylmethionine

1988
Ethanol, the choline requirement, methylation and liver injury.
    Life sciences, 1985, Sep-02, Volume: 37, Issue:9

    Topics: Animals; Betaine; Choline; Ethanol; Folic Acid; Homocysteine; Liver; Methionine; Methylation; Rats; Tetrahydrofolates

1985
Further syntheses in the study of structure-activity relationships of neuropharmacologically active amino acids.
    Journal of medicinal chemistry, 1965, Volume: 8, Issue:6

    Topics: Amino Alcohols; Animals; Aspartic Acid; Cats; Central Nervous System; Choline; Cysteine; Homocysteine; Muscle Spindles; Neurons; Serine; Sulfinic Acids

1965
[Action of 1:1 combination of phosphorylcholine and homocysteine on liver function, biliary secretion and cholesterolemia in the rat].
    Il Farmaco; edizione pratica, 1974, Volume: 29, Issue:3

    Topics: Animals; Bile; Cholesterol; Choline; Drug Therapy, Combination; Female; Homocysteine; Liver; Rats

1974
[Clinical trial of a new hepatoprotective preparation].
    La Clinica terapeutica, 1972, Jan-31, Volume: 60, Issue:2

    Topics: Alcoholism; Cholelithiasis; Choline; Diabetes Complications; Drug Combinations; Homocysteine; Humans; Lactones; Liver Diseases; Phosphoric Acids; Vitamin B 12

1972
The effect of methionine on folic acid and histidine metabolism in perfused rat liver.
    Biochimica et biophysica acta, 1972, Oct-25, Volume: 279, Issue:3

    Topics: Animals; Betaine; Carbon Dioxide; Carbon Isotopes; Choline; Deficiency Diseases; Drug Synergism; Ethionine; Folic Acid; Formates; Glutamates; Histidine; Homocysteine; Liver; Male; Methionine; Oxidation-Reduction; Peptides; Perfusion; Rats; Tetrahydrofolates; Vitamin B 12 Deficiency

1972
[Clinical experience with a new hepatoprotector].
    La Clinica terapeutica, 1969, Jun-15, Volume: 49, Issue:5

    Topics: Adolescent; Adult; Bilirubin; Choline; Gastrointestinal Diseases; Hepatitis; Homocysteine; Humans; Lactones; Liver; Liver Diseases; Male; Middle Aged; Transaminases

1969
[A hepato-protector in the treatment of long bed-ridden old persons affected with chronic diseases].
    Giornale di gerontologia, 1969, Volume: 17, Issue:3

    Topics: Aged; Choline; Chronic Disease; Homocysteine; Humans; Liver; Vitamin B 12

1969
Catabolism of betaine and its relationship to cobalamin overproduction.
    Biochimica et biophysica acta, 1971, Apr-20, Volume: 237, Issue:1

    Topics: Betaine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Choline; Coenzyme A; Glycine; Homocysteine; Methionine; Methylation; Nucleosides; Porphyrins; Pseudomonas; S-Adenosylmethionine; Succinates; Sucrose; Vitamin B 12

1971
[Protective effect of phosphorylcholine, homocysteine and their combination 1:1 in experimental hepatic lesions rats: comparison with the activity of choline and cysteine].
    Bollettino chimico farmaceutico, 1969, Volume: 108, Issue:4

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Choline; Cysteine; Dietary Fats; Drug Synergism; Guinea Pigs; Homocysteine; Liver; Male; Mice; Rats

1969
Growth-promoting and lipotropic effect of carnitine in rats fed diets limited in protein and methionine.
    The Journal of nutrition, 1965, Volume: 87, Issue:4

    Topics: Amino Acids; Animals; Betaine; Carnitine; Choline; Growth; Homocysteine; Lipid Metabolism; Liver; Male; Methionine; Protein Deficiency; Quaternary Ammonium Compounds; Rats; Threonine

1965
The biosynthesis of the methyl groups of choline in Ochromonas malhamensis.
    Archives of biochemistry and biophysics, 1966, Volume: 113, Issue:3

    Topics: Alkylation; Amino Alcohols; Choline; Eukaryota; Folic Acid; Homocysteine; In Vitro Techniques; Methionine; Microsomes; Mitochondria; Nucleosides; Phosphatidylcholines; Subcellular Fractions; Vitamin B 12

1966
First defined media for leptomonas spp. from insects.
    The Journal of protozoology, 1966, Volume: 13, Issue:3

    Topics: Choline; Culture Media; Eukaryota; Glycine; Homocysteine; Insecta; Lactones; Methionine; Pantothenic Acid; Vitamin B 12

1966
Labile methyl group balances in the human: the role of sarcosine.
    Metabolism: clinical and experimental, 1980, Volume: 29, Issue:8

    Topics: Adolescent; Child; Choline; Cystine; Diet; Female; Glycine; Homocysteine; Humans; Male; Methionine; Methylation; Nitrogen; Phosphatidylcholines; Sarcosine

1980
Severe folate deficiency causes secondary depletion of choline and phosphocholine in rat liver.
    The Journal of nutrition, 1994, Volume: 124, Issue:11

    Topics: Animals; Body Weight; Choline; Diet; Folic Acid; Folic Acid Deficiency; Homocysteine; Liver; Male; Phosphorylcholine; Rats; Rats, Sprague-Dawley

1994
Homocysteine increases as folate decreases in plasma of healthy men during short-term dietary folate and methyl group restriction.
    The Journal of nutrition, 1994, Volume: 124, Issue:7

    Topics: Adult; Choline; Diet; Folic Acid; Folic Acid Deficiency; Glycine max; Homocysteine; Humans; Male; Methionine; Middle Aged; Nutritional Requirements; Nutritional Status; Vitamin B 12

1994
Choline deficiency and methotrexate treatment induces marked but reversible changes in hepatic folate concentrations, serum homocysteine and DNA methylation rates in rats.
    Journal of the American College of Nutrition, 1995, Volume: 14, Issue:5

    Topics: Animals; Choline; Choline Deficiency; DNA Modification Methylases; Folic Acid; Folic Acid Antagonists; Homocysteine; Liver; Male; Methotrexate; Methylation; Rats; Rats, Wistar

1995
Hepatic betaine-homocysteine methyltransferase activity in the chicken is influenced by dietary intake of sulfur amino acids, choline and betaine.
    The Journal of nutrition, 1996, Volume: 126, Issue:8

    Topics: Amino Acids, Sulfur; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Chickens; Choline; Cystine; Diet; Dose-Response Relationship, Drug; Female; Homocysteine; Liver; Male; Methionine; Methyltransferases; Random Allocation

1996
The importance of transmethylation reactions to methionine metabolism in sheep: effects of supplementation with creatine and choline.
    The British journal of nutrition, 1996, Volume: 75, Issue:1

    Topics: Animals; Choline; Creatine; Homocysteine; Methionine; Methylation; Sheep; Wool

1996
Determinants of plasma homocysteine.
    The American journal of clinical nutrition, 1998, Volume: 68, Issue:4

    Topics: Choline; Homocysteine; Humans; Nutritional Status; Phosphatidylcholines

1998
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
    Journal of inherited metabolic disease, 1998, Volume: 21, Issue:8

    Topics: Amino Acid Metabolism, Inborn Errors; Benzoic Acid; Brain Diseases; Choline; Coma; Female; Glycine; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methionine; Methylation; Phosphatidylcholines; S-Adenosylmethionine; Seizures; Serine; Tetrahydrofolates

1998
Workshop on Folate, B12, and Choline. Sponsored by the Panel on Folate and other B vitamins of the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine, Washington, D.C., March 3-4,
    Nutrition (Burbank, Los Angeles County, Calif.), 1999, Volume: 15, Issue:1

    Topics: Biological Availability; Biomarkers; Cardiovascular Diseases; Choline; Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Male; Neoplasms; Neural Tube Defects; Nutrition Policy; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency

1999
Purification and kinetic properties of betaine-homocysteine methyltransferase from Aphanothece halophytica.
    Current microbiology, 2001, Volume: 43, Issue:2

    Topics: Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Chromatography, Agarose; Chromatography, Gel; Cyanobacteria; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methyltransferases; Molecular Weight; Sarcosine

2001
Renal tubulointerstitial injury in weanling rats with hyperhomocysteinemia.
    Kidney international, 2002, Volume: 62, Issue:4

    Topics: Age Factors; Animal Feed; Animals; Choline; Folic Acid; Homocysteine; Hyperhomocysteinemia; Methionine; Nephritis, Interstitial; Rats; Rats, Inbred F344; Weaning

2002
Metabolic response of normal and malignant tissue to acute and chronic methionine stress in athymic mice bearing human glial tumor xenografts.
    Chemical research in toxicology, 2002, Volume: 15, Issue:11

    Topics: Animals; Brain Neoplasms; Carbon-Sulfur Lyases; Choline; Choline Deficiency; Glioma; Homocysteine; Humans; Liver; Methionine; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous; Xenograft Model Antitumor Assays

2002
Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:3

    Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Dose-Response Relationship, Drug; Female; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Liver; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Mice; Mice, Knockout; Models, Biological; Oxidoreductases; Phosphorylcholine

2003
Transcriptional regulation of methionine synthase by homocysteine and choline in Aspergillus nidulans.
    The Biochemical journal, 2003, Dec-01, Volume: 376, Issue:Pt 2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aspergillus nidulans; Base Sequence; Betaine; Choline; Cloning, Molecular; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Homocysteine; Methionine; Models, Biological; Molecular Sequence Data; RNA, Messenger; Transcription, Genetic

2003
Choline biogenesis II. The effect of homocysteine on serine metabolism.
    Journal of neurochemistry, 1961, Volume: 6

    Topics: Choline; Cysteine; Homocysteine; Humans; Serine

1961
[Ethionine pancreatitis in the rat. II. Attempts to prevent ethionine injury by methionine, cysteine-homocysteine, choline and betaine].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1960, Volume: 20

    Topics: Animals; Betaine; Choline; Cysteine; Ethionine; Homocysteine; Methionine; Pancreatitis; Rats

1960
EXCITATION OF CEREBELLAR NEURONES BY ACETYLCHOLINE.
    Nature, 1963, Nov-09, Volume: 200

    Topics: Acetylcholine; Brain; Cats; Cerebellum; Choline; Electrophysiological Phenomena; Electrophysiology; Homocysteine; Neurochemistry; Neurons; Nicotine; Research

1963
[INFLUENCE OF VARIOUS METHYLATED SUBSTANCES SUPPLEMENTING SOJA FLOUR ON THE BIOSYNTHESIS OF TOTAL COBALAMINES AND VITAMINE B-12 BY STREPTOMYCES OLIVACEUS].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1963, Nov-18, Volume: 257

    Topics: Alkaloids; Choline; Corrinoids; Culture Media; Cystine; Dietary Supplements; Flour; Glycine max; Homocysteine; Metabolism; Research; Streptomyces; Vitamin B 12; Vitamin B Complex

1963
METHIONINE AND HOMOCYSTEINE AS PROTECTIVE AGENTS AGAINST IRRADIATION DAMAGE.
    Metabolism: clinical and experimental, 1964, Volume: 13

    Topics: Blood Proteins; Body Weight; Brain; Choline; Homocysteine; Methionine; Neoplasms, Radiation-Induced; Neurochemistry; Nucleic Acids; Protective Agents; Proteins; Radiation Protection; Rats; Reproduction; Research

1964
THE INFLUENCE OF ETHIONINE, METHIONINE, CHOLINE, AND RELATED COMPOUNDS ON LIVER GLYCOGEN DEPOSITION IN ADRENALECTOMIZED RATS: RELATION TO THE MODE OF ACTION OF GLUCOCORTICOIDS.
    Archives of biochemistry and biophysics, 1964, Volume: 107

    Topics: Adrenalectomy; Choline; Cysteine; Ethionine; Glucocorticoids; Glucose; Homocysteine; Hydrocortisone; Liver; Liver Glycogen; Methionine; Pharmacology; Research; Serine; Tyrosine

1964
STUDIES ON THE FORMATION OF BIOTIN FROM DESTHIOBIOTIN AND SULFATE IN SACCHAROMYCES CEREVISIAE. II. ON SULFUR SOURCES OF BIOTIN FORMATION BY WASHED CELL SUSPENSION OF YEAST.
    The Journal of vitaminology, 1964, Sep-10, Volume: 10

    Topics: Biotin; Choline; Culture Media; Cysteine; Cystine; Ethionine; Glucose; Glutathione; Homocysteine; Metabolism; Methionine; Research; Saccharomyces; Saccharomyces cerevisiae; Sulfates; Sulfur; Sulfur Oxides; Yeast, Dried

1964
VITAMIN B12 AND THE SYNTHESIS OF THE METHYL GROUPS OF CHOLINE IN OCHROMONAS MALHAMENSIS.
    Archives of biochemistry and biophysics, 1964, Volume: 108

    Topics: Alkylation; Carbon Isotopes; Choline; Coenzymes; Eukaryota; Formaldehyde; Formates; Homocysteine; Metabolism; Methionine; Ochromonas; Radiometry; Research; Tritium; Vitamin B 12

1964
Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency.
    Metabolism: clinical and experimental, 2004, Volume: 53, Issue:5

    Topics: Animal Feed; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine beta-Synthase; Cysteine; Female; Heterozygote; Homocysteine; Hyperhomocysteinemia; Lipotropic Agents; Liver; Male; Methionine; Methyltransferases; Mice; Mice, Inbred C57BL; Regression Analysis; Serine

2004
Betaine and folate status as cooperative determinants of plasma homocysteine in humans.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:2

    Topics: Adult; Aged; Betaine; Choline; Creatinine; Dose-Response Relationship, Drug; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Sarcosine; Vitamin B 12; Vitamin B 6

2005
Plasma choline and betaine and their relation to plasma homocysteine in normal pregnancy.
    The American journal of clinical nutrition, 2005, Volume: 81, Issue:6

    Topics: Adult; Africa, Western; Betaine; Black People; Choline; Dietary Supplements; Female; Folic Acid; Gestational Age; Hematinics; Homocysteine; Humans; Netherlands Antilles; Nutritional Status; Postpartum Period; Predictive Value of Tests; Pregnancy; Regression Analysis

2005
Choline, homocysteine, and pregnancy.
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:4

    Topics: Animals; Choline; Choline Deficiency; Female; Homocysteine; Humans; Lactation; Maternal Nutritional Physiological Phenomena; Nutritional Requirements; Pregnancy

2005
Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery.
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:4

    Topics: Betaine; Choline; Chromatography, Liquid; Creatinine; Cross-Sectional Studies; Female; Fetal Blood; Folic Acid; Health Status Indicators; Homocysteine; Humans; Infant, Newborn; Methylation; Oxidation-Reduction; Pregnancy; Regression Analysis; Sarcosine; Vitamin B 12

2005
Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study.
    The American journal of clinical nutrition, 2006, Volume: 83, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Betaine; Choline; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Sex Factors; Surveys and Questionnaires; Vitamin B Complex

2006
Effects of chronic betaine ingestion on methionine-loading induced plasma homocysteine elevation in rats.
    Journal of nutritional science and vitaminology, 2006, Volume: 52, Issue:3

    Topics: Analysis of Variance; Animals; Area Under Curve; Betaine; Betaine-Homocysteine S-Methyltransferase; Carnitine; Choline; Gastrointestinal Agents; Homocysteine; Injections, Intravenous; Liver; Male; Methionine; Rats; Rats, Wistar; Time Factors

2006
Medium-term methionine supplementation increases plasma homocysteine but not ADMA and improves blood pressure control in rats fed a diet rich in protein and adequate in folate and choline.
    European journal of nutrition, 2006, Volume: 45, Issue:7

    Topics: Adaptation, Physiological; Animals; Area Under Curve; Arginine; Blood Pressure; Choline; Dietary Proteins; Dietary Supplements; Folic Acid; Homocysteine; Male; Methionine; Methylation; Nitric Oxide; Random Allocation; Rats; Rats, Wistar; Time Factors

2006
Modulation of the homocysteine-betaine relationship by methylenetetrahydrofolate reductase 677 C->t genotypes and B-vitamin status in a large-scale epidemiological study.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:4

    Topics: Betaine; Choline; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamins

2007
Choline-related supplements improve abnormal plasma methionine-homocysteine metabolites and glutathione status in children with cystic fibrosis.
    The American journal of clinical nutrition, 2007, Volume: 85, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Choline; Cystic Fibrosis; Dietary Supplements; Female; Glutathione; Glutathione Disulfide; Homocysteine; Humans; Male; Methionine; Phosphatidylcholines

2007
Prospective study on dietary intakes of folate, betaine, and choline and cardiovascular disease risk in women.
    European journal of clinical nutrition, 2008, Volume: 62, Issue:3

    Topics: Aged; Betaine; Cardiovascular Diseases; Choline; Cohort Studies; Diet; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Middle Aged; Netherlands; Nutrition Surveys; Odds Ratio; Postmenopause; Prospective Studies; Surveys and Questionnaires

2008
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women.
    The American journal of clinical nutrition, 2007, Volume: 86, Issue:4

    Topics: Adult; Alcohol Drinking; Betaine; Biomarkers; Choline; Cross-Sectional Studies; Diet Records; Female; Folic Acid; Homocysteine; Humans; Linear Models; Lipotropic Agents; Methylation; Middle Aged; Predictive Value of Tests; Surveys and Questionnaires; Vitamin B Complex

2007
Is there a new component of the Mediterranean diet that reduces inflammation?
    The American journal of clinical nutrition, 2008, Volume: 87, Issue:2

    Topics: Betaine; Biomarkers; Choline; Confounding Factors, Epidemiologic; Diet Surveys; DNA Methylation; Epigenesis, Genetic; Feeding Behavior; Female; Greece; Homocysteine; Humans; Inflammation; Life Style; Male; Mediterranean Region; Promoter Regions, Genetic; United States

2008
Dietary choline and betaine intakes in relation to concentrations of inflammatory markers in healthy adults: the ATTICA study.
    The American journal of clinical nutrition, 2008, Volume: 87, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Betaine; Biomarkers; C-Reactive Protein; Choline; Cross-Sectional Studies; Diet Surveys; Fasting; Feeding Behavior; Female; Greece; Homocysteine; Humans; Inflammation; Interleukin-6; Life Style; Lipotropic Agents; Male; Middle Aged; Tumor Necrosis Factor-alpha

2008
Effects of homocysteine on metabolic pathways in cultured astrocytes.
    Neurochemistry international, 2008, Volume: 52, Issue:8

    Topics: Animals; Astrocytes; Brain; Cell Death; Cells, Cultured; Choline; Dose-Response Relationship, Drug; Energy Metabolism; Glucose; Homocysteine; Magnetic Resonance Spectroscopy; Membrane Potential, Mitochondrial; Mitochondria; NADP; Neurodegenerative Diseases; Protein Serine-Threonine Kinases; Pyruvate Carboxylase; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Rats; Rats, Wistar; Taurine

2008
Divergent associations of plasma choline and betaine with components of metabolic syndrome in middle age and elderly men and women.
    The Journal of nutrition, 2008, Volume: 138, Issue:5

    Topics: Aged; Betaine; Blood Glucose; Blood Pressure; Body Composition; Body Mass Index; Body Weights and Measures; Choline; Exercise; Female; Homocysteine; Humans; Lipids; Male; Metabolic Syndrome; Middle Aged; Triglycerides

2008
Hyperhomocysteinemia induced by guanidinoacetic acid is effectively suppressed by choline and betaine in rats.
    Bioscience, biotechnology, and biochemistry, 2008, Volume: 72, Issue:7

    Topics: Animals; Betaine; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Glycine; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Rats

2008
Equilibrated diet restores the effects of early age choline-deficient feeding on rat brain antioxidant status and enzyme activities: the role of homocysteine, L-phenylalanine and L-alanine.
    Metabolic brain disease, 2008, Volume: 23, Issue:3

    Topics: Acetylcholinesterase; Alanine; Animals; Antioxidants; Brain; Brain Chemistry; Ca(2+) Mg(2+)-ATPase; Choline; Diet; Female; Homocysteine; Lecithins; Male; Phenylalanine; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase

2008
Ethnicity and folate influence choline status in young women consuming controlled nutrient intakes.
    Journal of the American College of Nutrition, 2008, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Betaine; Black or African American; Body Mass Index; Choline; Diet; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mexican Americans; Middle Aged; Phosphatidylcholines; Sphingomyelins; White People

2008
Adequate Intake levels of choline are sufficient for preventing elevations in serum markers of liver dysfunction in Mexican American men but are not optimal for minimizing plasma total homocysteine increases after a methionine load.
    The American journal of clinical nutrition, 2008, Volume: 88, Issue:3

    Topics: Adolescent; Adult; Betaine; Choline; Genotype; Hispanic or Latino; Homocysteine; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Reference Values

2008
Tissue methionine cycle activity and homocysteine metabolism in female rats: impact of dietary methionine and folate plus choline.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 296, Issue:4

    Topics: Animals; Body Composition; Choline; Diet; Dietary Proteins; Female; Folic Acid; Homocysteine; Methionine; Models, Biological; Rats; Tissue Distribution

2009
Choline deprivation induces hyperhomocysteinemia in rats fed low methionine diets.
    Journal of nutritional science and vitaminology, 2008, Volume: 54, Issue:6

    Topics: Animals; Betaine; Choline; Choline Deficiency; Cysteine; Dietary Supplements; Growth; Homocysteine; Hyperhomocysteinemia; Lipotropic Agents; Liver; Male; Methionine; Rats; Rats, Wistar

2008
Genetic variants in phosphatidylethanolamine N-methyltransferase and methylenetetrahydrofolate dehydrogenase influence biomarkers of choline metabolism when folate intake is restricted.
    Journal of the American Dietetic Association, 2009, Volume: 109, Issue:2

    Topics: Adolescent; Adult; Biomarkers; Choline; Dose-Response Relationship, Drug; Female; Folic Acid; Folic Acid Deficiency; Genetic Variation; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Dehydrogenase (NADP); Mexican Americans; Nutritional Status; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Premenopause; Young Adult

2009
Hypohomocysteinemic effect of cysteine is associated with increased plasma cysteine concentration in rats fed diets low in protein and methionine levels.
    Journal of nutritional science and vitaminology, 2009, Volume: 55, Issue:1

    Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Caseins; Choline; Cystathionine beta-Synthase; Cysteic Acid; Cysteine; Diet, Protein-Restricted; Dietary Supplements; Glycine; Homocysteine; Hyperhomocysteinemia; Male; Mercaptoethylamines; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; Soybean Proteins

2009
Enhanced one-carbon flux towards DNA methylation: Effect of dietary methyl supplements against gamma-radiation-induced epigenetic modifications.
    Chemico-biological interactions, 2010, Feb-12, Volume: 183, Issue:3

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carbon; Choline; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gamma Rays; Homocysteine; Male; Mice; S-Adenosylmethionine; Time Factors

2010
Methyl donor deficiency affects fetal programming of gastric ghrelin cell organization and function in the rat.
    The American journal of pathology, 2010, Volume: 176, Issue:1

    Topics: Animals; Body Weight; Cell Lineage; Choline; Deficiency Diseases; Enteroendocrine Cells; Female; Fetal Development; Folic Acid; Gastric Mucosa; Ghrelin; Growth Hormone; Homocysteine; Immunohistochemistry; Pregnancy; Rats; Rats, Wistar; Vitamin B 12; Weaning

2010
Low dietary choline and low dietary riboflavin during pregnancy influence reproductive outcomes and heart development in mice.
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:4

    Topics: Animals; Choline; Diet; Female; Fetal Heart; Heart; Heart Defects, Congenital; Homocysteine; Lipotropic Agents; Liver; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Polymorphism, Genetic; Pregnancy; Pregnancy Outcome; Prenatal Nutritional Physiological Phenomena; Riboflavin; Vitamin B Complex

2010
Are dietary choline and betaine intakes determinants of total homocysteine concentration?
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:5

    Topics: Betaine; Cardiovascular Diseases; Choline; Cognition Disorders; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Vitamin B 12; Vitamin B 6

2010
Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism.
    The Journal of nutrition, 2010, Volume: 140, Issue:10

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Carbon; Choline; Diet; Fatty Liver; Female; Ferredoxin-NADP Reductase; Folic Acid; Folic Acid Deficiency; Gene Expression; Homocysteine; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; RNA, Messenger; Sex Factors

2010
Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.
    Nutrition research (New York, N.Y.), 2010, Volume: 30, Issue:7

    Topics: Amino Acids; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine beta-Synthase; Diet; Enzyme Inhibitors; Glycine N-Methyltransferase; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine

2010
Brain biochemical correlates of the plasma homocysteine level: a proton magnetic resonance spectroscopy study in the elderly subjects.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2011, Volume: 19, Issue:7

    Topics: Aged; Aspartic Acid; Basal Ganglia; Brain; Choline; Cobamides; Creatine; Female; Folic Acid; Frontal Lobe; Hippocampus; Homocysteine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Sex Characteristics

2011
Plasma choline concentration varies with different dietary levels of vitamins B6, B12 and folic acid in rats maintained on choline-adequate diets.
    The British journal of nutrition, 2012, Volume: 107, Issue:10

    Topics: Animals; Biological Availability; Choline; Diet; Dietary Supplements; Folic Acid; Homocysteine; Male; Methylation; Rats; Rats, Sprague-Dawley; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency

2012
Progression of prostate carcinogenesis and dietary methyl donors: temporal dependence.
    Cancer prevention research (Philadelphia, Pa.), 2012, Volume: 5, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Choline; Decitabine; Diet; Disease Progression; DNA Methylation; Folic Acid; Homocysteine; Humans; Male; Methionine; Mice; Mice, Nude; Prostatic Neoplasms; Tumor Cells, Cultured; Vitamin B 6

2012
Methylation capacity in children with severe cerebral palsy.
    European journal of clinical investigation, 2012, Volume: 42, Issue:7

    Topics: Betaine; Biomarkers; Case-Control Studies; Cerebral Palsy; Child; Child, Preschool; Choline; Cystathionine; DNA Methylation; Erythrocyte Indices; Erythrocyte Membrane; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Queensland; Severity of Illness Index; Uric Acid

2012
Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice.
    The American journal of clinical nutrition, 2012, Volume: 95, Issue:4

    Topics: Aminohydrolases; Animals; Choline; Choline Deficiency; Crosses, Genetic; Disease Models, Animal; Embryo Loss; Female; Fetal Growth Retardation; Folic Acid; Folic Acid Deficiency; Formate-Tetrahydrofolate Ligase; Genes, Lethal; Heterozygote; Homocysteine; Hypoxanthine; Maternal Nutritional Physiological Phenomena; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Mutant Strains; Multienzyme Complexes; Mutagenesis, Insertional; Neural Tube Defects; Pregnancy

2012
Effects of methyl-deficient diets on methionine and homocysteine metabolism in the pregnant rat.
    American journal of physiology. Endocrinology and metabolism, 2012, Jun-15, Volume: 302, Issue:12

    Topics: Animals; Choline; Cysteine; Diet; Female; Fetus; Folic Acid; Homocysteine; Kinetics; Litter Size; Liver; Methionine; Methylation; Pancreas; Phosphorylcholine; Placenta; Pregnancy; Rats; Triglycerides; Weight Gain

2012
Severe methylenetetrahydrofolate reductase deficiency in mice results in behavioral anomalies with morphological and biochemical changes in hippocampus.
    Molecular genetics and metabolism, 2012, Volume: 106, Issue:2

    Topics: Animals; Apoptosis; Behavior, Animal; Brain; Cerebellum; Choline; Choline O-Acetyltransferase; DNA Methylation; Hippocampus; Homocysteine; Homocystinuria; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Muscle Spasticity; Organ Size; Psychotic Disorders; Receptors, Glucocorticoid

2012
Factors contributing to the resistivity of a higher casein diet against choline deficiency-induced hyperhomocysteinemia in rats.
    Journal of nutritional science and vitaminology, 2012, Volume: 58, Issue:2

    Topics: Animals; Caseins; Choline; Choline Deficiency; Diet; Glycine; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats; Rats, Wistar; Serine

2012
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:4

    Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen

2013
Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration.
    The Journal of nutrition, 2013, Volume: 143, Issue:1

    Topics: Animals; Biomarkers; Choline; Cysteine; Disease Models, Animal; Folic Acid Deficiency; Heterozygote; Homocysteine; Isoenzymes; Liver; Male; Methionine; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutagenesis, Insertional; Mutant Proteins; Random Allocation

2013
Choline status and neurodevelopmental outcomes at 5 years of age in the Seychelles Child Development Nutrition Study.
    The British journal of nutrition, 2013, Jul-28, Volume: 110, Issue:2

    Topics: Betaine; Child Development; Child, Preschool; Choline; Cognition; Female; Homocysteine; Humans; Language; Linear Models; Longitudinal Studies; Male; Methionine; Neuropsychological Tests; Nutritional Status; Pregnancy; Sarcosine; Seychelles

2013
Betaine supplement alleviates hepatic triglyceride accumulation of apolipoprotein E deficient mice via reducing methylation of peroxisomal proliferator-activated receptor alpha promoter.
    Lipids in health and disease, 2013, Mar-13, Volume: 12

    Topics: Animals; Apolipoproteins E; Betaine; Carnitine O-Palmitoyltransferase; Choline; Cytochrome P-450 CYP2E1; DNA Methylation; Fatty Acid Synthase, Type I; Food, Formulated; Gene Expression Regulation; Glutathione Peroxidase; Homocysteine; Lipid Metabolism; Lipotropic Agents; Liver; Male; Mice; Mice, Inbred C57BL; PPAR alpha; Promoter Regions, Genetic; Signal Transduction; Superoxide Dismutase; Triglycerides

2013
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
    The American journal of clinical nutrition, 2013, Volume: 97, Issue:6

    Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult

2013
Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine.
    The American journal of clinical nutrition, 2013, Volume: 97, Issue:6

    Topics: Adult; Betaine; Choline; Dietary Supplements; Fasting; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Nutritional Status; Pregnancy; Sarcosine; Spain; Vitamin B 12

2013
Nicotinamide supplementation induces detrimental metabolic and epigenetic changes in developing rats.
    The British journal of nutrition, 2013, Volume: 110, Issue:12

    Topics: Animals; Betaine; Choline; CpG Islands; Dietary Supplements; DNA; DNA Damage; DNA Methylation; Epigenesis, Genetic; Glucose Intolerance; Homocysteine; Insulin Resistance; Liver; Male; Metabolic Diseases; Niacin; Niacinamide; Oxidative Stress; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Time Factors; Uracil; Vitamin B Complex; Weight Gain

2013
Impact of folic acid fortification on global DNA methylation and one-carbon biomarkers in the Women's Health Initiative Observational Study cohort.
    Epigenetics, 2014, Volume: 9, Issue:3

    Topics: Aged; Biomarkers; Choline; Cohort Studies; DNA Methylation; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Leukocytes; Middle Aged; Postmenopause

2014
Mouse model for deficiency of methionine synthase reductase exhibits short-term memory impairment and disturbances in brain choline metabolism.
    The Biochemical journal, 2014, Jul-15, Volume: 461, Issue:2

    Topics: Acetylcholinesterase; Animals; Apoptosis; Betaine; Cerebellum; Choline; Choline O-Acetyltransferase; Disease Models, Animal; DNA Methylation; Ferredoxin-NADP Reductase; Gene Expression; Hippocampus; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Male; Memory, Short-Term; Methionine; Mice; Mice, Knockout; Synaptic Transmission

2014
Plasma homocysteine, dietary B vitamins, betaine, and choline and risk of peripheral artery disease.
    Atherosclerosis, 2014, Volume: 235, Issue:1

    Topics: Adult; Aged; Betaine; Case-Control Studies; Choline; Cohort Studies; Diet; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Peripheral Arterial Disease; Proportional Hazards Models; Riboflavin; Risk Factors; Surveys and Questionnaires; Vitamin B Complex

2014
Increased systolic blood pressure in rat offspring following a maternal low-protein diet is normalized by maternal dietary choline supplementation.
    Journal of developmental origins of health and disease, 2012, Volume: 3, Issue:5

    Topics: Animals; Blood Pressure; Body Weight; Choline; Diet, Protein-Restricted; Dietary Supplements; Female; Homocysteine; Male; Maternal Nutritional Physiological Phenomena; Phosphatidylcholines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar

2012
Methyl-donor deficiency in adolescence affects memory and epigenetic status in the mouse hippocampus.
    Genes, brain, and behavior, 2015, Volume: 14, Issue:3

    Topics: Age Factors; Animals; Choline; Choline Deficiency; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Folic Acid Deficiency; Hippocampus; Homocysteine; Memory; Methionine; Mice; Mice, Inbred C57BL; Models, Animal; Nutritional Requirements; Promoter Regions, Genetic; Receptors, AMPA; Receptors, Glutamate

2015
[Betaine-enriched beet suppresses hyperhomocysteinemia induced by choline deficiency in rats].
    Wei sheng yan jiu = Journal of hygiene research, 2015, Volume: 44, Issue:2

    Topics: Amino Acids; Animals; Beta vulgaris; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Choline Deficiency; Cysteine; Diet; Dietary Supplements; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Rats; Rats, Wistar

2015
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats.
    Nutrients, 2015, Jun-04, Volume: 7, Issue:6

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Chickens; Choline; Cystathionine gamma-Lyase; Cysteine; Dietary Proteins; Folic Acid; Glycine; Homocysteine; Liver; Male; Meat; Methionine; Rats; Rats, Wistar; Riboflavin; RNA, Messenger; Sarcosine; Serine; Vitamin B 12; Vitamin B 6

2015
Betaine is as effective as folate at re-synthesizing methionine for protein synthesis during moderate methionine deficiency in piglets.
    European journal of nutrition, 2016, Volume: 55, Issue:8

    Topics: Animals; Betaine; Carbon Isotopes; Choline; Cysteine; Diet; Dietary Supplements; Folic Acid; Homocysteine; Methionine; Models, Biological; Oxidation-Reduction; Phenylalanine; Protein Biosynthesis; Swine

2016
Plasma 1-carbon metabolites and academic achievement in 15-yr-old adolescents.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016, Volume: 30, Issue:4

    Topics: Adolescent; Betaine; Choline; Cross-Sectional Studies; Educational Status; Female; Genotype; Homocysteine; Humans; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Phosphatidylethanolamine N-Methyltransferase; Polymorphism, Single Nucleotide; Social Class; Surveys and Questionnaires

2016
Multi-Vitamin B Supplementation Reverses Hypoxia-Induced Tau Hyperphosphorylation and Improves Memory Function in Adult Mice.
    Journal of Alzheimer's disease : JAD, 2016, 08-04, Volume: 54, Issue:1

    Topics: Animals; Avoidance Learning; Cerebral Cortex; Choline; Dietary Supplements; Disease Models, Animal; Folic Acid; Glycogen Synthase Kinase 3 beta; Hippocampus; Homocysteine; Hypoxia; Male; Maze Learning; Memory; Memory Disorders; Mice; Phosphorylation; tau Proteins; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2016
Comparison of the effects of nicotinic acid and nicotinamide degradation on plasma betaine and choline levels.
    Clinical nutrition (Edinburgh, Scotland), 2017, Volume: 36, Issue:4

    Topics: Adult; Betaine; Blood Pressure; Choline; Dietary Supplements; Food, Fortified; Homocysteine; Humans; Hydrolysis; Kinetics; Male; Metanephrine; Methylation; Niacin; Niacinamide; Normetanephrine; Pyridones; Random Allocation; Young Adult

2017
Prospective associations of maternal betaine status with offspring weight and body composition at birth: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort study.
    The American journal of clinical nutrition, 2016, Volume: 104, Issue:5

    Topics: Adipose Tissue; Adolescent; Adult; Betaine; Birth Weight; Body Composition; Body Mass Index; Choline; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Infant; Linear Models; Male; Methionine; Middle Aged; Nutritional Status; Prospective Studies; Sensitivity and Specificity; Singapore; Vitamin B 12; Young Adult

2016
Choline metabolic pathway gene polymorphisms and risk for Down syndrome: An association study in a population with folate-homocysteine metabolic impairment.
    European journal of clinical nutrition, 2017, Volume: 71, Issue:1

    Topics: Adult; Betaine-Homocysteine S-Methyltransferase; Case-Control Studies; Child; Choline; Choline Dehydrogenase; Down Syndrome; Female; Folic Acid; Genetic Association Studies; Genotype; Homocysteine; Humans; Metabolic Networks and Pathways; Mothers; Odds Ratio; Phosphatidylethanolamine N-Methyltransferase; Polymorphism, Single Nucleotide; Risk Factors

2017
Choline and its metabolites are differently associated with cardiometabolic risk factors, history of cardiovascular disease, and MRI-documented cerebrovascular disease in older adults.
    The American journal of clinical nutrition, 2017, Volume: 105, Issue:6

    Topics: Aged; Aged, 80 and over; Betaine; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Cerebrovascular Disorders; Cholesterol; Choline; Cross-Sectional Studies; Diabetes Mellitus; Female; Homocysteine; Humans; Hypertension; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphatidylcholines; Risk Factors; Triglycerides; Waist Circumference

2017
Oxidative stress and dietary micronutrient deficiencies contribute to overexpression of epigenetically regulated genes by lupus T cells.
    Clinical immunology (Orlando, Fla.), 2018, Volume: 196

    Topics: Adult; Aged; Case-Control Studies; CD4-Positive T-Lymphocytes; Choline; Diet; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Female; Flow Cytometry; Folic Acid; Gene Expression Regulation; Homocysteine; Humans; Lupus Erythematosus, Systemic; Male; Methionine; Micronutrients; Middle Aged; Oxidative Stress; Peroxynitrous Acid; Riboflavin; T-Lymphocytes; Vitamin B 12; Vitamin B 6; Young Adult; Zinc

2018
Caloric restriction can affect one-carbon metabolism during pregnancy in the rat: A transgenerational model.
    Biochimie, 2018, Volume: 152

    Topics: Animals; Betaine; Caloric Restriction; Carbon; Choline; DNA Methylation; Female; Gene Expression; Homocysteine; Hydrolases; Liver; Male; Methylamines; Models, Biological; Pregnancy; Pregnancy, Animal; Rats, Wistar; S-Adenosylmethionine

2018
Sex differences in hepatic one-carbon metabolism.
    BMC systems biology, 2018, 10-24, Volume: 12, Issue:1

    Topics: Betaine; Carbon; Choline; Female; Folic Acid; Homocysteine; Humans; Liver; Male; Models, Biological; Sex Characteristics

2018
Maternal choline supplementation ameliorates Alzheimer's disease pathology by reducing brain homocysteine levels across multiple generations.
    Molecular psychiatry, 2020, Volume: 25, Issue:10

    Topics: Alzheimer Disease; Animals; Brain; Choline; Dietary Supplements; Disease Models, Animal; Female; Homocysteine; Male; Mice; Mice, Transgenic

2020
Evaluating the therapeutic potential of one-carbon donors in nonalcoholic fatty liver disease.
    European journal of pharmacology, 2019, Mar-15, Volume: 847

    Topics: Animals; Betaine; Carbon; Choline; Diet, High-Fat; Dietary Supplements; DNA Methylation; Folic Acid; Glutathione; Homocysteine; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; S-Adenosylmethionine

2019
Total Methionine Restriction Treatment of Cancer.
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1866

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Choline; Homocysteine; Humans; Liver; Methionine; Mice, Nude; Neoplasms; Temozolomide; Xenograft Model Antitumor Assays

2019
Maternal betaine status, but not that of choline or methionine, is inversely associated with infant birth weight.
    The British journal of nutrition, 2019, Volume: 121, Issue:11

    Topics: Adult; Betaine; Birth Weight; Choline; Female; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Male; Maternal Nutritional Physiological Phenomena; Methionine; Pregnancy; Pregnancy Trimesters; Sarcosine

2019
Associations between folate and choline intake, homocysteine metabolism, and genetic polymorphism of MTHFR, BHMT and PEMT in healthy pregnant Polish women.
    Nutrition & dietetics: the journal of the Dietitians Association of Australia, 2020, Volume: 77, Issue:3

    Topics: Adolescent; Adult; Betaine-Homocysteine S-Methyltransferase; Choline; Female; Folic Acid; Genotype; Glutathione; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Phosphatidylethanolamine N-Methyltransferase; Poland; Polymorphism, Genetic; Pregnancy; Pregnancy Trimester, Third; Young Adult

2020
A novel approach in the management of hyperhomocysteinemia.
    Medical hypotheses, 2019, Volume: 129

    Topics: Alcohol Oxidoreductases; Animals; Choline; Cytidine Diphosphate Choline; Dietary Supplements; Endothelial Cells; Folic Acid; Homocysteine; Humans; Hydrolysis; Hyperhomocysteinemia; Kidney; Life Style; Liver; Methionine; Models, Theoretical; Vitamin B 12; Vitamin B 6

2019
Lower plasma glutathione, choline, and betaine concentrations are associated with fatty liver in postmenopausal women.
    Nutrition research (New York, N.Y.), 2022, Volume: 101

    Topics: Betaine; Biomarkers; Choline; Fatty Liver; Female; Folic Acid; Glutathione; Homocysteine; Humans; Postmenopause

2022
Nutritional biomarkers and heart failure requiring hospitalization in patients with type 2 diabetes: the SURDIAGENE cohort.
    Cardiovascular diabetology, 2022, 06-09, Volume: 21, Issue:1

    Topics: Aged; Betaine; Biomarkers; Carnitine; Choline; Cohort Studies; Cysteine; Diabetes Mellitus, Type 2; Female; Heart Failure; Homocysteine; Hospitalization; Humans; Male; Methionine; Middle Aged; Prospective Studies; Risk Factors

2022
Profiling of Homocysteine Metabolic Pathway Related Metabolites in Plasma of Diabetic Mellitus Based on LC-QTOF-MS.
    Molecules (Basel, Switzerland), 2023, Jan-09, Volume: 28, Issue:2

    Topics: Choline; Cysteine; Diabetes Mellitus; Homocysteine; Humans; Metabolic Networks and Pathways; Methionine; Racemethionine; Taurine

2023
[Association between maternal plasma one-carbon biomarkers during pregnancy and fetal growth in twin pregnancies].
    Zhonghua fu chan ke za zhi, 2023, Oct-25, Volume: 58, Issue:10

    Topics: Adult; Betaine; Biomarkers; Birth Weight; Choline; Cohort Studies; Female; Fetal Development; Fetal Weight; Homocysteine; Humans; Infant, Newborn; Methionine; Pregnancy; Pregnancy Outcome; Pregnancy Trimesters; Pregnancy, Twin

2023
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