homochlorocyclizine and cyclizine

homochlorocyclizine has been researched along with cyclizine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19904 (22.22)18.7374
1990's6 (33.33)18.2507
2000's4 (22.22)29.6817
2010's4 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Dulcey, AE; Ferrer, M; He, S; Hu, X; Hu, Z; Liang, TJ; Lin, B; Marugan, JJ; Rolt, A; Southall, N; Wang, AQ; Xiao, J; Xu, X; Zheng, W1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Arita, T; Fushida, H; Iseki, K; Kitagawa, S; Kunitomo, M; Miyake, K; Miyazaki, K; Nakai, A; Nishikata, M1
Arita, T; Fushida, H; Iseki, K; Miyake, K; Miyazaki, K; Nakai, A; Nishikata, M; Nomura, A2
Desowitz, RS; Palumbo, NE; Perri, SF; Sylvester, MS1
Arita, T; Fushida, H; Iseki, K; Miyake, K; Miyazaki, K; Nakai, A; Nishikata, M2
Horio, T; Miyauchi, H1
Furukori, H; Inoue, Y; Kaneko, S; Kondo, T; Mihara, K; Otani, K; Suzuki, A; Yasui-Furukori, N1
GIRARD, JP1
LECOMTE, J; TROQUET, J1
DONSON, N; KUGELMASS, IN; SAMUELS, L1
Bielejewska, A; Duszczyk, K; Zukowski, J1
Chikumi, H; Hitsuda, Y; Kodani, M; Kurai, J; Makino, H; Miyata, M; Sako, T; Shimizu, E; Touge, H; Watanabe, M1
Chang, TS; Chen, CT1

Trials

1 trial(s) available for homochlorocyclizine and cyclizine

ArticleYear
Histamine H1-receptor antagonists, promethazine and homochlorcyclizine, increase the steady-state plasma concentrations of haloperidol and reduced haloperidol.
    Therapeutic drug monitoring, 2003, Volume: 25, Issue:2

    Topics: Adult; Aged; Antipsychotic Agents; Cyclizine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Haloperidol; Histamine H1 Antagonists; Humans; Male; Middle Aged; Promethazine; Schizophrenia

2003

Other Studies

17 other study(ies) available for homochlorocyclizine and cyclizine

ArticleYear
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Discovery, Optimization, and Characterization of Novel Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection.
    Journal of medicinal chemistry, 2016, Feb-11, Volume: 59, Issue:3

    Topics: Dose-Response Relationship, Drug; Drug Discovery; Hepacivirus; Hepatitis C; Microbial Sensitivity Tests; Molecular Structure; Piperazines; Structure-Activity Relationship

2016
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Method for optical resolution of racemic homochlorcyclizine and comparison of optical isomers in antihistamine activity and pharmacokinetics.
    Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:5

    Topics: Animals; Cyclizine; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Male; Optical Rotation; Rats; Rats, Sprague-Dawley; Stereoisomerism

1992
Enantioselective pharmacokinetics of homochlorcyclizine. II: Disposition and metabolism of (+)-, (-)- and racemic homochlorcyclizine after oral administration to man.
    European journal of clinical pharmacology, 1992, Volume: 43, Issue:5

    Topics: Administration, Oral; Adult; Blood Proteins; Chromatography, High Pressure Liquid; Cyclizine; Erythrocytes; Glucuronates; Histamine H1 Antagonists; Humans; Male; Mass Spectrometry; Protein Binding; Reference Values; Stereoisomerism

1992
Inhibition of the adverse reaction to diethylcarbamazine in Dirofilaria immitis-infected dogs by lodoxamide ethyl.
    The American journal of tropical medicine and hygiene, 1982, Volume: 31, Issue:2

    Topics: Amino Acids; Animals; Cyclizine; Diethylcarbamazine; Dirofilaria immitis; Dirofilariasis; Dogs; Drug Evaluation, Preclinical; Indomethacin; Microfilariae; Oxamic Acid

1982
Effect of first-pass metabolism on enantioselective pharmacokinetics after oral administration of (+)-, (-)- and racemic homochlorcyclizine to rats.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:9

    Topics: Administration, Oral; Animals; Binding, Competitive; Chromatography, High Pressure Liquid; Cyclizine; Histamine H1 Antagonists; In Vitro Techniques; Injections, Intravenous; Liver; Male; Rats; Rats, Sprague-Dawley; Stereoisomerism

1994
Enantioselective pharmacokinetics of homochlorcyclizine: disposition of (+)- and (-)-homochlorcyclizine after intravenous and oral administration of racemic homochlorcyclizine to rats.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:7

    Topics: Administration, Oral; Animals; Bile; Blood Proteins; Brain; Chromatography, High Pressure Liquid; Cyclizine; Erythrocytes; Gastric Mucosa; Histamine H1 Antagonists; In Vitro Techniques; Injections, Intravenous; Intestinal Absorption; Intestinal Mucosa; Kidney; Liver; Lung; Male; Myocardium; Protein Binding; Rats; Rats, Sprague-Dawley; Spleen; Stereoisomerism; Tissue Distribution

1994
Enantioselective pharmacokinetics of homochlorcyclizine. III. Simultaneous determination of (+)- and (-)- homochlorcyclizine in human urine by high-performance liquid chromatography.
    Journal of chromatography, 1993, Feb-26, Volume: 612, Issue:2

    Topics: Adult; Chromatography, High Pressure Liquid; Cyclizine; Glucuronates; Histamine H1 Antagonists; Humans; Hydrogen-Ion Concentration; Solvents; Spectrophotometry, Ultraviolet; Stereoisomerism

1993
Detection of action, inhibition and augmentation spectra in solar urticaria.
    Dermatology (Basel, Switzerland), 1995, Volume: 191, Issue:4

    Topics: Anaphylaxis; Anti-Allergic Agents; Betamethasone; Cyclizine; Erythema; Female; Glucocorticoids; Histamine; Histamine H1 Antagonists; Humans; Light; Middle Aged; Molecular Weight; Photosensitizing Agents; Phthalazines; Radiation Dosage; Skin; Spectrophotometry; Spectrophotometry, Ultraviolet; Sunlight; Terfenadine; Ultrafiltration; Ultraviolet Rays; Urticaria

1995
[Clinical trials with a new anti-allergic agent, homochlorcyclizine. Effects on urinary elimination of the metabolite of serotonin].
    Therapeutische Umschau. Revue therapeutique, 1962, Volume: 19

    Topics: Anti-Allergic Agents; Cyclizine; Histamine H1 Antagonists; Humans; Serotonin

1962
[Anti-allergic properties of homochlorcyclizine in the rabbit].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1961, Volume: 155

    Topics: Animals; Anti-Allergic Agents; Cyclizine; Histamine H1 Antagonists; Hypersensitivity; Rabbits

1961
Homochlorcyclizine in bronchial allergic disease of infants and children.
    Annals of allergy, 1962, Volume: 20

    Topics: Asthma; Bronchial Diseases; Child; Cyclizine; Humans; Hypersensitivity; Immune System Diseases; Infant

1962
Effect of (+) or (-) camphorsulfonic acid additives to the mobile phase on enantioseparations of some basic drugs on a Chiralcel OD column.
    Journal of chromatography. A, 2005, Aug-12, Volume: 1083, Issue:1-2

    Topics: Benzoin; Camphor; Cellulose; Chromatography, High Pressure Liquid; Cyclizine; Ephedrine; Hydroxyzine; Imidazoles; Pharmaceutical Preparations; Phenylcarbamates; Stereoisomerism

2005
Acute eosinophilic pneumonia caused by calcium stearate, an additive agent for an oral antihistaminic medication.
    Internal medicine (Tokyo, Japan), 2006, Volume: 45, Issue:17

    Topics: Acute Disease; Administration, Oral; Aged; Cyclizine; Eosinophilia; Histamine H1 Antagonists; Humans; Male; Pruritus; Pulmonary Eosinophilia; Stearic Acids; Tablets

2006
Inhibitory effect of homochlorcyclizine on melanogenesis in α-melanocyte stimulating hormone-stimulated mouse B16 melanoma cells.
    Archives of pharmacal research, 2012, Volume: 35, Issue:1

    Topics: alpha-MSH; Animals; Cell Line, Tumor; Cell Survival; Cyclizine; Dose-Response Relationship, Drug; Melanins; Mice; Skin Pigmentation

2012