Page last updated: 2024-08-26

homocarnosine and gamma-aminobutyric acid

homocarnosine has been researched along with gamma-aminobutyric acid in 55 studies

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199025 (45.45)18.7374
1990's15 (27.27)18.2507
2000's12 (21.82)29.6817
2010's0 (0.00)24.3611
2020's3 (5.45)2.80

Authors

AuthorsStudies
Hansen, S; Kish, SJ; Perry, TL1
Gjessing, LR; Kish, SJ; Løken, AC; Nesbakken, R; Perry, TL; Schrader, H; Sjaastad, O1
Bondarenko, TI; Makletsova, MG; Uskova, NI1
Drescher, DG; Drescher, MJ1
Ben-Menachem, E; Haegele, KD; Huebert, N; Mumford, J; Persson, LI1
Mendzheritskiĭ, AM; Povilaĭtite, PE; Uskova, NI1
Gjessing, LR; Lenney, JF; Lunde, HA; Mørkrid, L; Sjaastad, O1
Ben Menachem, E; Haegele, KD; Hardenberg, J; Huebert, N; Persson, L; Schechter, PJ1
Ben-Menachem, E; Dahlgren, L; Haegele, KD; Hardenberg, J; Huebert, N; Mumford, JP; Persson, LI; Schechter, PJ1
Halonen, T; Pitkanen, A; Riekkinen, PJ; Sivenius, J; Ylinen, A1
Ferraro, TN; Hare, TA; Manyam, BV1
Agid, Y; Bonnet, AM; De Smet, Y; Grove, J; Saint-Hilaire, MH; Schechter, PJ; Tell, G1
Nagai, K; Suda, T2
Hansen, S; Perry, TL; Wall, RA1
Matilainen, R; Pitkänen, A; Riekkinen, P; Ruutiainen, T1
Gaio, JM; Hommel, M; Perret, J; Pollak, P1
Haegele, KD; Schechter, PJ; Schmitt, AH; Schoun, J; Schwartz, JJ1
Bondarenko, TI; Khodakova, AA; Mendzheritskaia, LG1
Brucher, JM; Casaer, P; Corbeel, L; de Cock, P; Eeckels, R; Eggermont, E; Jaeken, J; Schechter, PJ1
Dow, R; Fink, G; Grieve, G; Mitchell, R1
Grove, J; Palfreyman, MG; Schechter, PJ1
Gauthier, SG; Hansen, S; Perry, TL; Wall, RA1
Børresen, AL; Gjessing, LR; Haugan, I; Hole, K; Sjaastad, O; Ziesler, O1
Bondarenko, TI; Makletsova, MG; Sukhomovskiĭ, BI1
Grove, J; Koch-Weser, J; Marescaux, C; Rumbach, L; Schechter, PJ; Sjoerdsma, A; Tell, G; Warter, JM1
Grove, J; Huot, S; Palfreyman, MG1
Bauer, K; Hallermayer, K; Hamprecht, B; Kleinkauf, H; Salnikow, J1
Grove, J; Koch-Weser, J; Marescaux, C; Rumbach, L; Schechter, PJ; Tell, G; Warter, JM1
Agid, Y; de Smet, Y; Grove, J; Hanke, NF; Koch-Weser, J; Schechter, PJ; Tell, G1
Dufy, B; Lorsignol, A; Taupignon, A1
Halonen, T; Kälviäinen, R; Pitkänen, A; Riekkinen, PJ1
Jackson, MC; Lenney, JF; Mack, RJ; Scollard, DM1
Gibson, KM; Jaeken, J; Jakobs, C1
Lysenko, AV; Mendzheritskii, AM; Uskova, NI1
Behar, KL; Petroff, OA; Prichard, JW; Rothman, DL1
Behar, KL; Hyder, F; Mattson, RH; Petroff, OA; Rothman, DL1
Hyder, F; Mattson, RH; Petroff, OA; Rothman, DL5
Behar, KL; Charney, DS; Delaney, R; Hooten, M; Krystal, JH; Navarro, V; Petersen, KF; Petrakis, IL; Petroff, OA; Rothman, DL; Shulman, GI1
Collins, T; Hyder, F; Mattson, RH; Petroff, OA; Rothman, DL1
Boesiger, P; Duc, CO; Meier, D; Mueller, SG; Russ, W; Weber, B; Weber, OM; Wieser, HG1
Almai, A; Behar, KL; Charney, DS; Goddard, AW; Krystal, JH; Mason, GF; Petroff, OA; Rothman, DL1
Barker, GJ; Duncan, JS; McLean, MA; Simister, RJ3
Gibson, KM; Pearl, PL1
Gibson, KM; Jakobs, C; Jansen, EE; Shigematsu, Y; Verhoeven, NM1
Arning, E; Bottiglieri, T; Gibson, KM; Hager, EJ; Homanics, GE; Jakobs, C; Jansen, EE; Paul, HS; Skvorak, KJ; Strom, SC; Sun, Q; Zinnanti, WJ1
Deelchand, DK; Henry, PG; Marjańska, M; Terpstra, M1
Juchem, C; Landheer, K; Petroff, OA; Prinsen, H; Rothman, DL1
Arima, T; Egusa, A; Komaru, T; Kumrungsee, T; Oishi, Y; Sato, K; Sato, M; Yanaka, N1

Reviews

2 review(s) available for homocarnosine and gamma-aminobutyric acid

ArticleYear
Inherited disorders of GABA metabolism.
    Journal of inherited metabolic disease, 1993, Volume: 16, Issue:4

    Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Carnosine; Dipeptidases; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Succinate-Semialdehyde Dehydrogenase

1993
Clinical aspects of the disorders of GABA metabolism in children.
    Current opinion in neurology, 2004, Volume: 17, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Brain; Carnosine; Child; Developmental Disabilities; Diagnosis, Differential; Epilepsy; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Magnetic Resonance Imaging; Phenotype; Pyridoxal Phosphate; Pyridoxine; Succinate-Semialdehyde Dehydrogenase

2004

Trials

4 trial(s) available for homocarnosine and gamma-aminobutyric acid

ArticleYear
Vigabatrin increases human brain homocarnosine and improves seizure control.
    Annals of neurology, 1998, Volume: 44, Issue:6

    Topics: Adult; Anticonvulsants; Carnosine; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Osmolar Concentration; Treatment Outcome; Vigabatrin

1998
Effects of vigabatrin on brain GABA+/CR signals in patients with epilepsy monitored by 1H-NMR-spectroscopy: responder characteristics.
    Epilepsia, 2001, Volume: 42, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Brain; Brain Chemistry; Carnosine; Creatine; Epilepsy; Epilepsy, Temporal Lobe; Female; Functional Laterality; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Phosphocreatine; Treatment Outcome; Vigabatrin

2001
Proton MRS reveals frontal lobe metabolite abnormalities in idiopathic generalized epilepsy.
    Neurology, 2003, Oct-14, Volume: 61, Issue:7

    Topics: Adolescent; Adult; Anticonvulsants; Aspartic Acid; Carnosine; Epilepsy, Generalized; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Reference Values; Valproic Acid

2003
Proton MR spectroscopy of metabolite concentrations in temporal lobe epilepsy and effect of temporal lobe resection.
    Epilepsy research, 2009, Volume: 83, Issue:2-3

    Topics: Adolescent; Adult; Aspartic Acid; Brain Chemistry; Brain Mapping; Carnosine; Creatine; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Young Adult

2009

Other Studies

49 other study(ies) available for homocarnosine and gamma-aminobutyric acid

ArticleYear
Regional distribution of homocarnosine, homocarnosine-carnosine synthetase and homocarnosinase in human brain.
    Journal of neurochemistry, 1979, Volume: 32, Issue:6

    Topics: Adult; Alanine; Brain; Brain Chemistry; Carnosine; Dipeptidases; Dipeptides; gamma-Aminobutyric Acid; Humans; Kinetics; Peptide Synthases; Substrate Specificity; Tissue Distribution

1979
Homocarnosinosis: increased content of homocarnosine and deficiency of homocarnosinase in brain.
    Journal of neurochemistry, 1979, Volume: 32, Issue:6

    Topics: Adult; Brain; Carnosine; Dipeptidases; Dipeptides; Epilepsy; Female; gamma-Aminobutyric Acid; Histidine; Humans; Lysine; Middle Aged

1979
[Use of gamma-aminobutyric acid from various sources in the synthesis of homocarnosine in the brain of animals of various ages].
    Biokhimiia (Moscow, Russia), 1992, Volume: 57, Issue:9

    Topics: Aging; Animals; Brain; Carbon Radioisotopes; Carnosine; gamma-Aminobutyric Acid; Putrescine; Rats

1992
N-acetylhistidine, glutamate, and beta-alanine are concentrated in a receptor cell layer of the trout inner ear.
    Journal of neurochemistry, 1991, Volume: 56, Issue:2

    Topics: Animals; beta-Alanine; Carnosine; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hair Cells, Auditory; Histidine; Saccule and Utricle; Trout

1991
Effect of long-term vigabatrin therapy on selected neurotransmitter concentrations in cerebrospinal fluid.
    Journal of child neurology, 1991, Volume: Suppl 2

    Topics: Adult; Aminocaproates; Anticonvulsants; Carnosine; Electroencephalography; Epilepsy, Complex Partial; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Long-Term Care; Male; Methoxyhydroxyphenylglycol; Middle Aged; Vigabatrin

1991
[Brain gamma-aminobutyric acid and homocarnosine in stress].
    Nervnaia sistema, 1991, Volume: 30

    Topics: Animals; Brain; Brain Chemistry; Carnosine; Delta Sleep-Inducing Peptide; gamma-Aminobutyric Acid; Hyperbaric Oxygenation; Piracetam; Rats; Restraint, Physical; Stress, Physiological

1991
Inborn errors of carnosine and homocarnosine metabolism.
    Journal of neural transmission. Supplementum, 1990, Volume: 29

    Topics: Adult; Aged; Carnosine; Dipeptides; Female; gamma-Aminobutyric Acid; Humans; Male; Metabolism, Inborn Errors; Middle Aged

1990
Cerebrospinal fluid parameters in healthy volunteers during serial lumbar punctures.
    Journal of neurochemistry, 1989, Volume: 52, Issue:2

    Topics: Adult; Albumins; Carnosine; Cerebrospinal Fluid Proteins; Dipeptides; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Immunoglobulin G; Male; Reference Values; Spinal Puncture

1989
The effect of different vigabatrin treatment regimens on CSF biochemistry and seizure control in epileptic patients.
    British journal of clinical pharmacology, 1989, Volume: 27 Suppl 1

    Topics: Adult; Aminocaproates; Anticonvulsants; Carnosine; Cerebrospinal Fluid Proteins; Epilepsy; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Vigabatrin

1989
Cerebrospinal fluid GABA and seizure control with vigabatrin.
    British journal of clinical pharmacology, 1989, Volume: 27 Suppl 1

    Topics: Adolescent; Adult; Aminocaproates; Anticonvulsants; Carnosine; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Seizures; Vigabatrin

1989
Evaluation of amino acid neurotransmitters, related compounds, and precursors in dystonia.
    Advances in neurology, 1988, Volume: 50

    Topics: Adult; Amino Acids; Analysis of Variance; Carnosine; Dystonia; Ethanolamine; Ethanolamines; gamma-Aminobutyric Acid; Glutamine; Humans; Neurotransmitter Agents

1988
Cerebrospinal fluid GABA and homocarnosine concentrations in patients with Friedreich's ataxia, Parkinson's disease, and Huntington's chorea.
    Movement disorders : official journal of the Movement Disorder Society, 1987, Volume: 2, Issue:2

    Topics: Adult; Aged; Carnosine; Dipeptides; Female; Friedreich Ataxia; gamma-Aminobutyric Acid; Humans; Huntington Disease; Levodopa; Male; Middle Aged; Parkinson Disease

1987
[Immunoregulative effects of homocarnosine and gamma-aminobuthyric acid].
    Nihon seirigaku zasshi. Journal of the Physiological Society of Japan, 1986, Volume: 48, Issue:6

    Topics: Aging; Animals; Antibody Formation; Carnosine; Dipeptides; gamma-Aminobutyric Acid; Homeostasis; Immunity; Immunity, Cellular; Mice; Mitomycin; Mitomycins; Wound Healing

1986
Brain amino compounds in a Huntington's disease patient on isoniazid therapy.
    Neurology, 1985, Volume: 35, Issue:5

    Topics: Adult; Brain Chemistry; Carnosine; Caudate Nucleus; Cerebellar Nuclei; gamma-Aminobutyric Acid; Humans; Huntington Disease; Isoniazid; Male; Putamen; Substantia Nigra

1985
Levels of total gamma-aminobutyric acid (GABA), free GABA and homocarnosine in cerebrospinal fluid of epileptic patients before and during gamma-vinyl-GABA (vigabatrin) treatment.
    Journal of the neurological sciences, 1988, Volume: 88, Issue:1-3

    Topics: Adolescent; Adult; Aminocaproates; Carnosine; Dipeptides; Dose-Response Relationship, Drug; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Male; Vigabatrin

1988
Clinical and biochemical effects of gamma-vinyl Gaba in tardive dyskinesia.
    Journal of neurology, neurosurgery, and psychiatry, 1987, Volume: 50, Issue:12

    Topics: Aged; Aminocaproates; Carnosine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Mental Disorders; Vigabatrin

1987
2-Pyrrolidinone in human cerebrospinal fluid: a major constituent of total gamma-aminobutyric acid.
    Journal of neurochemistry, 1987, Volume: 49, Issue:5

    Topics: Adult; Carnosine; Female; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Mass Spectrometry; Middle Aged; Pyrrolidinones

1987
[Immuno-enhancing actions of carnosine and homocarnosine].
    Nihon seirigaku zasshi. Journal of the Physiological Society of Japan, 1986, Volume: 48, Issue:11

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carnosine; Dipeptides; gamma-Aminobutyric Acid; Immunity; Male; Mice

1986
[Age and the role of certain mediators in the sensitivity of animals to hyperbaric oxygenation].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1980, Volume: 66, Issue:8

    Topics: Age Factors; Animals; Brain Chemistry; Carnosine; Dipeptides; gamma-Aminobutyric Acid; Histamine; Histidine; Hyperbaric Oxygenation; Neurotransmitter Agents; Rabbits; Rats

1980
Gamma-aminobutyric acid-transaminase deficiency: a newly recognized inborn error of neurotransmitter metabolism.
    Neuropediatrics, 1984, Volume: 15, Issue:3

    Topics: 4-Aminobutyrate Transaminase; beta-Alanine; Brain; Carnosine; Diffuse Cerebral Sclerosis of Schilder; Female; gamma-Aminobutyric Acid; Gigantism; Humans; Infant; Infant, Newborn; Male; Metabolism, Inborn Errors; Neurotransmitter Agents

1984
Endogenous GABA receptor ligands in hypophysial portal blood.
    Neuroendocrinology, 1983, Volume: 37, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Animals; Brain; Carnosine; Electric Stimulation; gamma-Aminobutyric Acid; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A

1983
Cerebrospinal fluid GABA as an index of brain GABA activity.
    Clinical neuropharmacology, 1983, Volume: 6, Issue:3

    Topics: Adult; Aged; Brain; Carnosine; gamma-Aminobutyric Acid; Humans; Middle Aged; Synaptic Transmission

1983
Human CSF GABA concentrations: revised downward for controls, but not decreased in Huntington's chorea.
    Journal of neurochemistry, 1982, Volume: 38, Issue:3

    Topics: Carbon Radioisotopes; Carnosine; gamma-Aminobutyric Acid; Humans; Huntington Disease; Reference Values

1982
Transport and distribution of homocarnosine after intracerebroventricular and intravenous injection in the rat.
    Neurochemical research, 1984, Volume: 9, Issue:5

    Topics: Animals; Biological Transport; Brain; Carnosine; Chromatography, High Pressure Liquid; Dipeptides; gamma-Aminobutyric Acid; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Synaptosomes; Tissue Distribution

1984
[Concentration of free amino acids and homocarnosine dipeptide in the cerebrospinal fluid of children with hydrocephalus].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1983, Volume: 83, Issue:10

    Topics: Amino Acids; Carnosine; Cerebral Ventricles; Child, Preschool; Dipeptides; gamma-Aminobutyric Acid; Humans; Hydrocephalus; Infant; Intellectual Disability; Meningitis; Subarachnoid Space

1983
Increased gamma-aminobutyric acid (GABA), homocarnosine and beta-alanine in cerebrospinal fluid of patients treated with gamma-vinyl GABA (4-amino-hex-5-enoic acid).
    Life sciences, 1981, May-21, Volume: 28, Issue:21

    Topics: 4-Aminobutyrate Transaminase; Adult; Aged; Alanine; Aminocaproates; beta-Alanine; Carnosine; Chromatography, Ion Exchange; Dipeptides; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Spectrometry, Fluorescence; Vigabatrin

1981
Total GABA and homocarnosine in CSF as indices of brain GABA concentrations.
    Neuroscience letters, 1983, Feb-21, Volume: 35, Issue:2

    Topics: Aminocaproates; Animals; Brain; Carnosine; Dipeptides; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains; Vigabatrin

1983
Biosynthesis of carnosine and related peptides by glial cells in primary culture.
    The Journal of biological chemistry, 1982, Apr-10, Volume: 257, Issue:7

    Topics: Alanine; Animals; Animals, Newborn; Brain; Carnosine; Cells, Cultured; Dipeptides; gamma-Aminobutyric Acid; Kinetics; Mice; Neuroglia

1982
Artifactual increases in the concentration of free GABA in samples of human cerebrospinal fluid are due to degradation of homocarnosine.
    Journal of neurochemistry, 1982, Volume: 39, Issue:4

    Topics: Carnosine; Dipeptides; False Positive Reactions; gamma-Aminobutyric Acid; Humans; Time Factors

1982
Concentration gradients of free and total gamma-aminobutyric acid and homocarnosine in human CSF: comparison of suboccipital and lumbar sampling.
    Journal of neurochemistry, 1982, Volume: 39, Issue:6

    Topics: Adult; Aged; Carnosine; Dipeptides; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Spinal Puncture

1982
Short applications of gamma-aminobutyric acid increase intracellular calcium concentrations in single identified rat lactotrophs.
    Neuroendocrinology, 1994, Volume: 60, Issue:4

    Topics: Animals; Calcium; Calcium Channel Blockers; Carnosine; Clonazepam; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Ion Channel Gating; Membrane Potentials; Muscimol; Patch-Clamp Techniques; Pituitary Gland, Anterior; Radioimmunoassay; Rats; Rats, Wistar; Receptors, GABA-A

1994
Amino acid levels in the cerebrospinal fluid of newly diagnosed epileptic patients: effect of vigabatrin and carbamazepine monotherapies.
    Journal of neurochemistry, 1993, Volume: 60, Issue:4

    Topics: Adolescent; Adult; Amino Acids; Aminocaproates; Carbamazepine; Carnosine; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Vigabatrin

1993
Localization of a novel pathway for the liberation of GABA in the human CNS.
    Brain research bulletin, 1994, Volume: 33, Issue:4

    Topics: Animals; Antibody Specificity; Carnosine; Central Nervous System; Dipeptidases; gamma-Aminobutyric Acid; Humans; Immunoenzyme Techniques; Immunohistochemistry; Mice; Mice, Inbred BALB C

1994
[Comparative investigation of anticonvulsive effects of putrescine and structural analogues of delta-sleep-inducing peptide].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 1996, Issue:9

    Topics: Animals; Brain; Carnosine; Delta Sleep-Inducing Peptide; gamma-Aminobutyric Acid; Hyperbaric Oxygenation; Lipid Peroxidation; Male; Putrescine; Rats; Seizures

1996
Homocarnosine and the measurement of neuronal pH in patients with epilepsy.
    Magnetic resonance in medicine, 1997, Volume: 38, Issue:6

    Topics: Adult; Anticonvulsants; Brain Chemistry; Carnosine; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Vigabatrin

1997
Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy.
    Neurology, 1999, Volume: 52, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Brain; Carnosine; Epilepsy; Female; Fructose; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pyrrolidinones; Topiramate

1999
Preliminary evidence of low cortical GABA levels in localized 1H-MR spectra of alcohol-dependent and hepatic encephalopathy patients.
    The American journal of psychiatry, 1999, Volume: 156, Issue:6

    Topics: Adult; Age of Onset; Alcoholism; Carnosine; Cerebral Cortex; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Protons; Radionuclide Imaging

1999
Acute effects of vigabatrin on brain GABA and homocarnosine in patients with complex partial seizures.
    Epilepsia, 1999, Volume: 40, Issue:7

    Topics: Administration, Oral; Adult; Anticonvulsants; Brain; Brain Chemistry; Carnosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy, Complex Partial; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Vigabatrin

1999
Effects of gabapentin on brain GABA, homocarnosine, and pyrrolidinone in epilepsy patients.
    Epilepsia, 2000, Volume: 41, Issue:6

    Topics: Acetates; Adult; Amines; Anticonvulsants; Brain Chemistry; Carnosine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Occipital Lobe; Pyrrolidinones

2000
Homocarnosine and seizure control in juvenile myoclonic epilepsy and complex partial seizures.
    Neurology, 2001, Mar-27, Volume: 56, Issue:6

    Topics: Adult; Aged; Carnosine; Epilepsy, Complex Partial; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Myoclonic Epilepsy, Juvenile; Time Factors

2001
Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy.
    Archives of general psychiatry, 2001, Volume: 58, Issue:6

    Topics: Adult; Agoraphobia; Ambulatory Care; Carnosine; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Panic Disorder

2001
Topiramate rapidly raises brain GABA in epilepsy patients.
    Epilepsia, 2001, Volume: 42, Issue:4

    Topics: Administration, Oral; Anticonvulsants; Brain Chemistry; Carnosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy, Complex Partial; Fructose; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Occipital Lobe; Pyrrolidinones; Stimulation, Chemical; Topiramate

2001
A proton magnetic resonance spectroscopy study of metabolites in the occipital lobes in epilepsy.
    Epilepsia, 2003, Volume: 44, Issue:4

    Topics: Adolescent; Adult; Aspartic Acid; Carnosine; Epilepsies, Partial; Epilepsy, Generalized; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Image Enhancement; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neural Inhibition; Occipital Lobe; Synaptic Transmission

2003
A novel, quantitative assay for homocarnosine in cerebrospinal fluid using stable-isotope dilution liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Jan-18, Volume: 830, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carnosine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Deuterium; Female; gamma-Aminobutyric Acid; Humans; Infant; Male; Mass Spectrometry; Middle Aged; Radioisotope Dilution Technique; Reference Standards; Reference Values; Reproducibility of Results

2006
Brain homocarnosine and seizure control of patients taking gabapentin or topiramate.
    Epilepsia, 2006, Volume: 47, Issue:3

    Topics: Adult; Amines; Anticonvulsants; Brain Chemistry; Carnosine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy, Complex Partial; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neocortex; Topiramate; Treatment Outcome; Visual Cortex

2006
Hepatocyte transplantation (HTx) corrects selected neurometabolic abnormalities in murine intermediate maple syrup urine disease (iMSUD).
    Biochimica et biophysica acta, 2009, Volume: 1792, Issue:10

    Topics: Animals; Brain; Carnosine; gamma-Aminobutyric Acid; Hepatocytes; Humans; Liver; Maple Syrup Urine Disease; Mice; Models, Biological; Neurotransmitter Agents

2009
MEGA-PRESS of GABA+: Influences of acquisition parameters.
    NMR in biomedicine, 2021, Volume: 34, Issue:5

    Topics: Carnosine; Computer Simulation; gamma-Aminobutyric Acid; Humans; Macromolecular Substances; Magnetic Resonance Spectroscopy

2021
Elevated homocarnosine and GABA in subject on isoniazid as assessed through 1H MRS at 7T.
    Analytical biochemistry, 2020, 06-15, Volume: 599

    Topics: Adult; Brain Chemistry; Carnosine; Female; gamma-Aminobutyric Acid; Healthy Volunteers; Humans; Isoniazid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Young Adult

2020
Dietary GABA induces endogenous synthesis of a novel imidazole peptide homocarnosine in mouse skeletal muscles.
    Amino acids, 2020, Volume: 52, Issue:5

    Topics: Animals; beta-Alanine; Carnosine; Diet; Feeding Behavior; GABA Agents; gamma-Aminobutyric Acid; Imidazoles; Male; Mice; Mice, Inbred ICR; Muscle, Skeletal

2020