Page last updated: 2024-08-20

homoarginine and n,n-dimethylarginine

homoarginine has been researched along with n,n-dimethylarginine in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (2.70)29.6817
2010's31 (83.78)24.3611
2020's5 (13.51)2.80

Authors

AuthorsStudies
Carru, C; Carta, F; Deiana, L; Gaspa, L; Pinna, A; Sotgia, S; Zinellu, A; Zinellu, E1
Gunduz, O; Karadag, CH; Ulugol, A1
Altun, GD; Aydogdu, N; Gunduz, O; Karadag, H; Kaya, O; Torun, N; Vardar, SA1
Akolekar, R; Jordan, J; Khalil, AA; Nicolaides, KH; Tsikas, D1
Davids, M; Teerlink, T1
Balestrieri, ML; Casale, R; Castaldo, D; Cautela, D; D'Onofrio, N; Giovane, A; Servillo, L1
Beckmann, B; Gutzki, FM; Jordan, J; Kayacelebi, AA; Tsikas, D1
Atzler, D; Böger, RH; Friedrich, N; Ittermann, T; Nauck, M; Schwedhelm, E1
Doerfer, J; Grulich-Henn, J; Grünert, SC; Holder, M; Krebs, A; Lichte, K; Schmidt-Trucksäss, A; Schwab, KO; Stier, B; Winkler, K; Wöhrl, J1
Hahn, A; Jordan, J; Kayacelebi, AA; Pham, VV; Stichtenoth, DO; Tsikas, D; Willers, J1
Frölich, JC; Hahn, A; Kayacelebi, AA; Pham, VV; Rothmann, S; Schneider, JY; Tsikas, D; Willers, J1
Kienreich, K; März, W; Meinitzer, A; Pieber, TR; Pilz, S; Putz-Bankuti, C; Stauber, RE; Stojakovic, T1
Atzler, D; Chobanyan-Jürgens, K; Choe, CU; Frölich, JC; Huneau, JF; Kayacelebi, AA; Langen, J; Lücke, T; Mariotti, F; Rothmann, S; Schneider, JY; Schwedhelm, E; Tsikas, D; Weigt-Usinger, K1
Beckmann, B; Gold, R; Haghikia, A; Hanff, E; Kayacelebi, AA; Tsikas, D1
Beckmann, B; Carmann, C; Chobanyan-Jürgens, K; Hörster, I; Kayacelebi, AA; Köhler, C; Lücke, T; Schara, U; Tsikas, D; Weigt-Usinger, K1
Androulakis, E; Antoniades, C; Papageorgiou, N; Papaioannou, S; Tousoulis, D1
Beckmann, B; Carmann, C; Hörster, I; Kayacelebi, AA; Langen, J; Lilienthal, E; Lücke, T; Richter-Unruh, A; Tsikas, D; Weigt-Usinger, K1
Bazer, FW; Che, D; Hou, Y; Hu, S; Jia, S; Nawaratna, G; Wang, F; Wu, G1
Bauersachs, J; Bavendiek, U; Bledau, N; Haghikia, A; Hanff, E; Kayacelebi, AA; Sonnenschein, K; Tsikas, D; Weissenborn, K; Widera, C; Yanchev, GR1
Chafai, A; Fromm, MF; König, J; Maas, R1
Günes, DN; Hanff, E; Kayacelebi, AA; Lundgren, J; Redfors, B; Tsikas, D1
Burt, MG; Drake, SM; Mangelsdorf, BL; Mangoni, AA; Radhakutty, A; Rowland, A; Smith, MD; Thompson, CH1
Da Boit, M; Elliot, DJ; Gray, SR; Lewis, BC; Mangoni, AA; Tommasi, S1
Bjørke-Monsen, AL; Fløtre, CH; Helm, T; Lund, A; Svingen, GFT; Ueland, PM; Varsi, K1
Brodmann, M; Gary, T; Hackl, G; Hafner, F; Jud, P; Meinitzer, A; Seinost, G; Verheyen, N1
Bollenbach, A; Hanff, E; Tsikas, D1
Atzler, D; Böger, RH; Choe, CU; Cordts, K; Gerloff, C; Grant, PJ; Grzybowski, R; Hornig, S; Lezius, S; Lüneburg, N; Magnus, T; Neu, A; Schwedhelm, E; Thomalla, G1
Fromm, MF; König, J; Maas, R; Taghikhani, E1
Bollenbach, A; Brunner, G; Hanff, E; Tsikas, D1
Chyrchel, B; Hanff, E; Kuźniewski, M; Surdacki, A; Tsikas, D; Wieczorek-Surdacka, E1
Carru, C; Mangoni, AA; McEvoy, M; Rodionov, RN; Sotgia, S; Zinellu, A1
Auge, D; Chafai, A; Fromm, MF; Gessner, A; Maas, R; Mieth, M; Müller, F1
Bahls, M; Böger, RH; Büttner, P; Hindricks, G; Kornej, J; Schwedhelm, E; Thiele, H1
Böger, RH; Botha-Le Roux, S; Fourie, CMT; Mels, CMC; Mokhaneli, MC; Schwedhelm, E1
Bassu, S; Carru, C; Castagna, F; Erre, GL; Mangoni, AA; Passiu, G; Piga, M; Sotgia, S; Zinellu, A1
Fromm, MF; Gessner, A; König, J; Maas, R; Taghikhani, E; Taudte, RV1
Beckmann, B; Brinkmann, F; Dillenhöfer, S; Frank, M; Hamelmann, E; Hanusch, B; Holtmann, M; Jöckel, KH; Koerner-Rettberg, C; Langrock, C; Legenbauer, T; Lücke, T; Maasjosthusmann, P; Reinehr, T; Sinningen, K; Tsikas, D1

Reviews

2 review(s) available for homoarginine and n,n-dimethylarginine

ArticleYear
Homoarginine in the shadow of asymmetric dimethylarginine: from nitric oxide to cardiovascular disease.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Amidinotransferases; Animals; Arginine; Atherosclerosis; Endothelium, Vascular; Homoarginine; Humans; Nitric Oxide; Nitric Oxide Synthase Type III

2015
New horizons in arginine metabolism, ageing and chronic disease states.
    Age and ageing, 2019, 11-01, Volume: 48, Issue:6

    Topics: Aged; Aging; Arginine; Chronic Disease; Homoarginine; Humans

2019

Trials

6 trial(s) available for homoarginine and n,n-dimethylarginine

ArticleYear
Decreased levels of homoarginine and asymmetric dimethylarginine in children with type 1 diabetes: associations with cardiovascular risk factors but no effect by atorvastin.
    Journal of pediatric endocrinology & metabolism : JPEM, 2015, Volume: 28, Issue:1-2

    Topics: Adolescent; Anticholesteremic Agents; Arginine; Atorvastatin; Cardiovascular Diseases; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glycated Hemoglobin; Heptanoic Acids; Homoarginine; Humans; Lipids; Male; Pilot Projects; Pyrroles; Risk Factors; Treatment Outcome

2015
Plasma homoarginine, arginine, asymmetric dimethylarginine and total homocysteine interrelationships in rheumatoid arthritis, coronary artery disease and peripheral artery occlusion disease.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Aged; Arginine; Arthritis, Rheumatoid; Coronary Artery Disease; Female; Homoarginine; Homocysteine; Humans; Male; Middle Aged; Peripheral Arterial Disease

2015
Biosynthesis of homoarginine (hArg) and asymmetric dimethylarginine (ADMA) from acutely and chronically administered free L-arginine in humans.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Adolescent; Adult; Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Arginine; Child; Coronary Artery Disease; Developmental Disabilities; Female; Guanidinoacetate N-Methyltransferase; Homoarginine; Humans; Intellectual Disability; Language Development Disorders; Male; Mice; Mice, Knockout; Middle Aged; Movement Disorders; Peripheral Arterial Disease; Speech Disorders

2015
Serum and cerebrospinal fluid concentrations of homoarginine, arginine, asymmetric and symmetric dimethylarginine, nitrite and nitrate in patients with multiple sclerosis and neuromyelitis optica.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Adult; Arginine; Female; Homoarginine; Humans; Male; Middle Aged; Multiple Sclerosis; Neuromyelitis Optica; Nitrates; Nitrites

2015
The L-arginine/NO pathway and homoarginine are altered in Duchenne muscular dystrophy and improved by glucocorticoids.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Adolescent; Adult; Arginine; Child; Child, Preschool; Cross-Sectional Studies; Glucocorticoids; Homoarginine; Humans; Infant; Male; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Nitric Oxide; Pilot Projects

2015
Homoarginine (hArg) and asymmetric dimethylarginine (ADMA) in short stature children without and with growth hormone deficiency: hArg and ADMA are involved differently in growth in the childhood.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Adolescent; Adult; Arginine; Child; Female; Growth Disorders; Homoarginine; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Male

2015

Other Studies

29 other study(ies) available for homoarginine and n,n-dimethylarginine

ArticleYear
High-throughput CZE-UV determination of arginine and dimethylated arginines in human plasma.
    Electrophoresis, 2007, Volume: 28, Issue:12

    Topics: Arginine; Electrophoresis, Capillary; Homoarginine; Humans; Plasma; Spectrophotometry, Ultraviolet

2007
Modulatory role of the endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine (ADMA), in morphine tolerance and dependence in mice.
    Journal of neural transmission (Vienna, Austria : 1996), 2010, Volume: 117, Issue:9

    Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Drug Tolerance; Homoarginine; Male; Mice; Mice, Inbred BALB C; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Pain Measurement

2010
The alteration of asymmetric dimetilarginine (ADMA) levels in cardiac and gastrocnemius muscles following radioactive iodine application in guinea pigs and the effect of L-carnitine on this alteration.
    International journal of radiation biology, 2011, Volume: 87, Issue:1

    Topics: Animals; Arginine; Carnitine; Guinea Pigs; Heart; Homoarginine; Iodine Radioisotopes; Male; Muscle, Skeletal; Myocardium; Radiation-Protective Agents; Thyroid Hormones

2011
Asymmetric dimethylarginine, arginine and homoarginine at 11-13 weeks' gestation and preeclampsia: a case-control study.
    Journal of human hypertension, 2013, Volume: 27, Issue:1

    Topics: Adult; Arginine; Case-Control Studies; Female; Gas Chromatography-Mass Spectrometry; Homoarginine; Humans; Nitric Oxide; Pre-Eclampsia; Pregnancy; Regression Analysis

2013
Plasma concentrations of arginine and asymmetric dimethylarginine do not reflect their intracellular concentrations in peripheral blood mononuclear cells.
    Metabolism: clinical and experimental, 2013, Volume: 62, Issue:10

    Topics: Arginine; Biomarkers; Homoarginine; Humans; Leukocytes, Mononuclear; Nitric Oxide

2013
Determination of homoarginine, arginine, NMMA, ADMA, and SDMA in biological samples by HPLC-ESI-mass spectrometry.
    International journal of molecular sciences, 2013, Oct-09, Volume: 14, Issue:10

    Topics: Arginine; Chromatography, High Pressure Liquid; Homoarginine; Humans; Tandem Mass Spectrometry

2013
GC-MS and GC-MS/MS measurement of the cardiovascular risk factor homoarginine in biological samples.
    Amino acids, 2014, Volume: 46, Issue:9

    Topics: Arginine; Cardiovascular Diseases; Female; Gas Chromatography-Mass Spectrometry; Homoarginine; Humans; Male; Risk Factors; Sputum

2014
Serum reference intervals of homoarginine, ADMA, and SDMA in the study of health in Pomerania.
    Clinical chemistry and laboratory medicine, 2014, Volume: 52, Issue:12

    Topics: Adult; Aged; Arginine; Biomarkers; Body Mass Index; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Female; Homoarginine; Humans; Male; Middle Aged; Reference Values; Renal Insufficiency, Chronic; Risk Factors; Tandem Mass Spectrometry

2014
Plasma homoarginine (hArg) and asymmetric dimethylarginine (ADMA) in patients with rheumatoid arthritis: is homoarginine a cardiovascular corrective in rheumatoid arthritis, an anti-ADMA?
    International journal of cardiology, 2014, Oct-20, Volume: 176, Issue:3

    Topics: Arginine; Arthritis, Rheumatoid; Biomarkers; Female; Homoarginine; Humans; Male

2014
Association of homoarginine and methylarginines with liver dysfunction and mortality in chronic liver disease.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Adult; Aged; Arginine; Chronic Disease; Disease-Free Survival; Female; Follow-Up Studies; Homoarginine; Humans; Liver Cirrhosis; Male; Middle Aged; Retrospective Studies; Survival Rate

2015
Whole-body synthesis of L-homoarginine in pigs and rats supplemented with L-arginine.
    Amino acids, 2016, Volume: 48, Issue:4

    Topics: Animal Feed; Animals; Arginine; Body Weight; Creatinine; Dietary Supplements; Female; Glycine max; Homoarginine; Male; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Swine; Zea mays

2016
The role of L-arginine/L-homoarginine/nitric oxide pathway for aortic distensibility and intima-media thickness in stroke patients.
    Amino acids, 2017, Volume: 49, Issue:6

    Topics: Aorta; Arginine; Atherosclerosis; Endothelium, Vascular; Female; Homoarginine; Humans; Male; Middle Aged; Nitric Oxide; Stroke; Ultrasonography; Vascular Remodeling

2017
The prognostic biomarker L-homoarginine is a substrate of the cationic amino acid transporters CAT1, CAT2A and CAT2B.
    Scientific reports, 2017, 07-06, Volume: 7, Issue:1

    Topics: Amino Acid Transport Systems, Basic; Arginine; Biological Transport, Active; Cationic Amino Acid Transporter 1; Gene Expression; HEK293 Cells; Homoarginine; Humans; Kinetics; Protein Isoforms; Substrate Specificity; Transgenes

2017
Metabolism and distribution of pharmacological homoarginine in plasma and main organs of the anesthetized rat.
    Amino acids, 2017, Volume: 49, Issue:12

    Topics: Amidinotransferases; Animals; Arginine; Glycine; Guanidinoacetate N-Methyltransferase; Half-Life; Homoarginine; Humans; Kidney; Lipid Peroxidation; Malondialdehyde; Models, Animal; Nitric Oxide Synthase; Pilot Projects; Rats; Rats, Sprague-Dawley; Takotsubo Cardiomyopathy; Tissue Distribution

2017
Opposing effects of rheumatoid arthritis and low dose prednisolone on arginine metabolomics.
    Atherosclerosis, 2017, Volume: 266

    Topics: Administration, Oral; Aged; Arginine; Arthritis, Rheumatoid; Biomarkers; Case-Control Studies; Chromatography, Liquid; Drug Administration Schedule; Endothelium, Vascular; Female; Glucocorticoids; Homoarginine; Humans; Male; Mass Spectrometry; Metabolomics; Middle Aged; Prednisolone; Time Factors; Treatment Outcome

2017
Homoarginine and inhibition of human arginase activity: kinetic characterization and biological relevance.
    Scientific reports, 2018, 02-27, Volume: 8, Issue:1

    Topics: Aged; Aged, 80 and over; Agmatine; Arginase; Arginine; Cell Line; Chromatography, Liquid; Enzyme Activation; Female; Homoarginine; Humans; Kinetics; Male; Proline; Protein Isoforms; Tandem Mass Spectrometry

2018
Plasma Homoarginine Concentrations According to Use of Hormonal Contraception.
    Scientific reports, 2018, 08-15, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Arginine; Chromatography, Liquid; Contraception; Contraceptives, Oral, Hormonal; Estrogens; Female; Homoarginine; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Progestins; Tandem Mass Spectrometry; Young Adult

2018
Homoarginine/ADMA ratio and homoarginine/SDMA ratio as independent predictors of cardiovascular mortality and cardiovascular events in lower extremity arterial disease.
    Scientific reports, 2018, 09-21, Volume: 8, Issue:1

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Cardiovascular System; Female; Homoarginine; Humans; Incidence; Lower Extremity; Male; Middle Aged; Prospective Studies; Risk Factors; Vascular Diseases

2018
Utility of homoarginine in the GC-MS quantification of asymmetric dimethylarginine (ADMA) in human serum proteins.
    Analytical biochemistry, 2018, 12-15, Volume: 563

    Topics: Aged; Amino Acids; Arginine; Blood Proteins; Female; Gas Chromatography-Mass Spectrometry; Homoarginine; Humans; Male

2018
Guanidino compound ratios are associated with stroke etiology, internal carotid artery stenosis and CHA
    Journal of the neurological sciences, 2019, 02-15, Volume: 397

    Topics: Aged; Arginine; Biomarkers; Brain Ischemia; Carotid Arteries; Carotid Stenosis; Cross-Sectional Studies; Female; Homoarginine; Humans; Intracranial Hemorrhages; Male; Middle Aged; Recurrence; Stroke

2019
The renal transport protein OATP4C1 mediates uptake of the uremic toxin asymmetric dimethylarginine (ADMA) and efflux of cardioprotective L-homoarginine.
    PloS one, 2019, Volume: 14, Issue:3

    Topics: Arginine; Cardiovascular Diseases; HEK293 Cells; Homoarginine; Humans; Inhibitory Concentration 50; Kidney; Kinetics; Organic Anion Transporters; Toxins, Biological

2019
Asymmetric dimethylation and citrullination of proteinic arginine and homoarginine synthesis in human Helicobacter pylori infection.
    Amino acids, 2019, Volume: 51, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Citrullination; Citrulline; Female; Gas Chromatography-Mass Spectrometry; Helicobacter Infections; Helicobacter pylori; Homoarginine; Humans; Lysine; Male; Methylation; Middle Aged; Nitric Oxide; Ornithine

2019
Distinct associations between plasma osteoprotegerin, homoarginine and asymmetric dimethylarginine in chronic kidney disease male patients with coronary artery disease.
    Amino acids, 2019, Volume: 51, Issue:6

    Topics: Aged; Arginine; Biomarkers; Coronary Artery Disease; Homoarginine; Humans; Male; Middle Aged; Osteoprotegerin; Renal Insufficiency, Chronic

2019
Establishment of reference values for the lysine acetylation marker N
    Amino acids, 2019, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Arginine; Biomarkers; Cardiovascular Diseases; Carnitine; Chromatography, Liquid; Citrulline; Creatinine; Female; Homoarginine; Humans; Lysine; Male; Middle Aged; Ornithine; Reference Values; Renal Insufficiency, Chronic; Tandem Mass Spectrometry; Young Adult

2019
Arginine derivatives in atrial fibrillation progression phenotypes.
    Journal of molecular medicine (Berlin, Germany), 2020, Volume: 98, Issue:7

    Topics: Aged; Arginine; Atrial Fibrillation; Biomarkers; Cohort Studies; Disease Progression; Female; Homoarginine; Humans; Male; Middle Aged; Phenotype

2020
Asymmetric dimethylarginine and L-homoarginine prospectively relate to carotid wall thickness in a South African cohort.
    Amino acids, 2020, Volume: 52, Issue:6-7

    Topics: Aged; Arginine; Black People; Blood Pressure; Carotid Intima-Media Thickness; Cohort Studies; Female; Homoarginine; Humans; Male; Middle Aged; Nitric Oxide; Prospective Studies; Ultrasonography

2020
Comprehensive arginine metabolomics and peripheral vasodilatory capacity in rheumatoid arthritis: A monocentric cross-sectional study.
    Microvascular research, 2020, Volume: 131

    Topics: Aged; Aged, 80 and over; Arginine; Arthritis, Rheumatoid; Biomarkers; Case-Control Studies; Citrulline; Cross-Sectional Studies; Female; Fingers; Homoarginine; Humans; Italy; Male; Metabolomics; Middle Aged; Vasodilation

2020
Vectorial transport of the arginine derivatives asymmetric dimethylarginine (ADMA) and L-homoarginine by OATP4C1 and P-glycoprotein studied in double-transfected MDCK cells.
    Amino acids, 2020, Volume: 52, Issue:6-7

    Topics: Animals; Arginine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dogs; Homoarginine; Humans; Madin Darby Canine Kidney Cells; Organic Anion Transporters; Transcytosis; Transfection

2020
Characterization of the L-Arginine/Nitric Oxide Pathway and Oxidative Stress in Pediatric Patients with Atopic Diseases.
    International journal of molecular sciences, 2022, Feb-15, Volume: 23, Issue:4

    Topics: Arginine; Asthma; Child; Dermatitis, Atopic; Female; Homoarginine; Humans; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress; Signal Transduction

2022