Compounds > holmium
Page last updated: 2024-08-22

holmium and lactic acid

holmium has been researched along with lactic acid in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (15.79)18.2507
2000's12 (63.16)29.6817
2010's4 (21.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jay, M; Mumper, RJ1
Jay, M; Mumper, RJ; Ryo, UY1
Nijsen, JF; Rook, DW; Swildens-van Woudenberg, IA; van het Schip, AD; van Rijk, PP; Woittiez, JR; Zonnenberg, BA1
Brandt, C; de Klerk, J; Dullens, H; Hennink, W; Meijer, R; Nijsen, F; Rook, D; van het Schip, F; van Rijk, P; Zonnenberg, B1
De Witte, A; Hennink, WE; Kooijman, H; Kroon-Batenburg, LM; Nijsen, JF; Talsma, H; van De Weert, M; van Rijk, PP; Van Schip, AD; van Steenbergen, MJ1
Dullens, HF; Hennink, W; Kicken, M; Koole, R; Nijsen, JF; Slootweg, PJ; van der Bilt, A; van Es, RJ1
Dullens, HF; Koole, R; Nijsen, JF; Slootweg, PJ; van Es, RJ; van het Schip, AD1
Hennink, WE; Kroon-Batenburg, LM; Nijsen, JF; van de Weert, M; van Het Schip, AD; van Rijk, PP; van Steenbergen, MJ; Zielhuis, SW1
Feddes, B; Figueiredo, R; Hennink, WE; Nijsen, JF; van het Schip, AD; Vredenberg, AM; Zielhuis, SW1
de Roos, R; Hennink, WE; Krijger, GC; Nijsen, JF; van het Schip, AD; van Rijk, PP; Zielhuis, SW1
Dorland, L; Hennink, WE; Krijger, GC; Nijsen, JF; van Het Schip, AD; Zielhuis, SW1
Hennink, WE; Krijger, GC; Nijsen, JF; van het Schip, AD; Zielhuis, SW1
Bakker, CJ; Dullens, HF; Hennink, WE; Krijger, GC; Nijsen, JF; Seppenwoolde, JH; van het Schip, AD; van Rijk, PP; Zielhuis, SW; Zonnenberg, BA1
de Wit, TC; Huisman, A; Krijger, GC; Nijsen, JF; Seevinck, PR; Seppenwoolde, JH; van den Ingh, TS; van het Schip, AD; Vente, MA; Zonnenberg, BA1
de Leege, PF; de Roos, R; Hennink, WE; Kaaijk, CN; Koster-Ammerlaan, MJ; Krijger, GC; Nijsen, JF; van Het Schip, AD; van Steenbergen, MJ; Vente, MA1
Bakker, CJ; Bult, W; de Jong, HW; de Wit, TC; Krijger, GC; Nijsen, JF; Seevinck, PR; van den Bosch, MA; van het Schip, AD; Vente, MA; Zonnenberg, BA1
Bakker, CJ; de Wit, TC; Nijsen, JF; Seevinck, PR; van de Maat, GH; Vente, MA1
Bakker, CJ; de Jong, HW; Elschot, M; Lam, MG; Nijsen, JF; Seevinck, PR; Smits, ML; van de Maat, GH; van den Bosch, MA; van het Schip, AD; Verkooijen, HM; Zonnenberg, BA1
Abolghasemi, H; Yavari, K; Yeganeh, E1

Trials

1 trial(s) available for holmium and lactic acid

ArticleYear
In vivo dosimetry based on SPECT and MR imaging of 166Ho-microspheres for treatment of liver malignancies.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2013, Volume: 54, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Embolization, Therapeutic; Female; Holmium; Humans; Lactic Acid; Liver; Liver Neoplasms; Magnetic Resonance Imaging; Male; Microspheres; Middle Aged; Multimodal Imaging; Polyesters; Polymers; Radiometry; Safety; Tomography, Emission-Computed, Single-Photon

2013

Other Studies

18 other study(ies) available for holmium and lactic acid

ArticleYear
Poly(L-lactic acid) microspheres containing neutron-activatable holmium-165: a study of the physical characteristics of microspheres before and after irradiation in a nuclear reactor.
    Pharmaceutical research, 1992, Volume: 9, Issue:1

    Topics: Bacillus; Calorimetry, Differential Scanning; Holmium; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Microspheres; Molecular Weight; Neutrons; Nuclear Reactors; Polyesters; Polymers; Radioisotopes; Spectrophotometry, Infrared; Time Factors

1992
Neutron-activated holmium-166-poly (L-lactic acid) microspheres: a potential agent for the internal radiation therapy of hepatic tumors.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1991, Volume: 32, Issue:11

    Topics: Animals; Biodegradation, Environmental; Brachytherapy; Holmium; Lactates; Lactic Acid; Liver Neoplasms, Experimental; Microspheres; Neutrons; Polyesters; Polymers; Rabbits; Radioisotopes

1991
Holmium-166 poly lactic acid microspheres applicable for intra-arterial radionuclide therapy of hepatic malignancies: effects of preparation and neutron activation techniques.
    European journal of nuclear medicine, 1999, Volume: 26, Issue:7

    Topics: Brachytherapy; Drug Delivery Systems; Holmium; Humans; Lactic Acid; Liver Neoplasms; Microspheres; Neutron Activation Analysis; Polyesters; Polymers; Radioisotopes

1999
Targeting of liver tumour in rats by selective delivery of holmium-166 loaded microspheres: a biodistribution study.
    European journal of nuclear medicine, 2001, Volume: 28, Issue:6

    Topics: Animals; Autoradiography; Excipients; Holmium; Lactic Acid; Liver; Liver Neoplasms; Male; Microspheres; Polyesters; Polymers; Radioisotopes; Radionuclide Imaging; Rats; Rats, Inbred Strains; Tissue Distribution; Whole-Body Counting

2001
Characterization of poly(L-lactic acid) microspheres loaded with holmium acetylacetonate.
    Biomaterials, 2001, Volume: 22, Issue:22

    Topics: Biocompatible Materials; Calorimetry, Differential Scanning; Embolization, Therapeutic; Holmium; Humans; Hydroxybutyrates; In Vitro Techniques; Lactic Acid; Liver Neoplasms; Materials Testing; Microscopy, Electron, Scanning; Microspheres; Pentanones; Polyesters; Polymers; Spectrophotometry, Infrared; X-Ray Diffraction

2001
Tumour embolization of the Vx2 rabbit head and neck cancer model with Dextran hydrogel and Holmium-poly(L-lactic acid) microspheres: a radionuclide and histological pilot study.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2001, Volume: 29, Issue:5

    Topics: Analysis of Variance; Animals; Brachytherapy; Dextrans; Embolization, Therapeutic; Extravasation of Diagnostic and Therapeutic Materials; Female; Head and Neck Neoplasms; Holmium; Lactic Acid; Microspheres; Neoplasms, Experimental; Particle Size; Pilot Projects; Polyesters; Polymers; Rabbits; Radioisotopes; Radionuclide Imaging; Technetium

2001
Intra-arterial embolization of head-and-neck cancer with radioactive holmium-166 poly(L-lactic acid) microspheres: an experimental study in rabbits.
    International journal of oral and maxillofacial surgery, 2001, Volume: 30, Issue:5

    Topics: Animals; Arteries; Brachytherapy; Carcinoma, Squamous Cell; Ear, External; Embolization, Therapeutic; Female; Head and Neck Neoplasms; Holmium; Lactic Acid; Microspheres; Polyesters; Polymers; Rabbits; Radiation Injuries; Radioisotopes; Radiopharmaceuticals; Remission Induction

2001
Influence of neutron irradiation on holmium acetylacetonate loaded poly(L-lactic acid) microspheres.
    Biomaterials, 2002, Volume: 23, Issue:8

    Topics: Calorimetry, Differential Scanning; Embolization, Therapeutic; Gamma Rays; Holmium; Humans; Hydroxybutyrates; Lactic Acid; Liver Neoplasms; Microscopy, Electron, Scanning; Microspheres; Molecular Weight; Neutrons; Pentanones; Polyesters; Polymers; Radioisotopes; Spectrophotometry; Temperature; X-Ray Diffraction

2002
Surface characteristics of holmium-loaded poly(L-lactic acid) microspheres.
    Biomaterials, 2005, Volume: 26, Issue:8

    Topics: Holmium; Lactic Acid; Liver Neoplasms; Microscopy, Electron, Scanning; Microspheres; Polyesters; Polymers; Polyvinyl Alcohol; Spectrum Analysis

2005
Production of GMP-grade radioactive holmium loaded poly(L-lactic acid) microspheres for clinical application.
    International journal of pharmaceutics, 2006, Mar-27, Volume: 311, Issue:1-2

    Topics: Brachytherapy; Guidelines as Topic; Holmium; Lactic Acid; Microspheres; Neutrons; Nuclear Reactors; Particle Size; Polyesters; Polymers; Quality Control; Radioisotopes; Surface Properties; Technology, Pharmaceutical; Temperature

2006
Removal of chloroform from biodegradable therapeutic microspheres by radiolysis.
    International journal of pharmaceutics, 2006, Jun-06, Volume: 315, Issue:1-2

    Topics: Biodegradation, Environmental; Chloroform; Drug Contamination; Gamma Rays; Holmium; Lactic Acid; Microspheres; Molecular Weight; Neutrons; Polyesters; Polymers; Radioisotopes

2006
Holmium-loaded poly(L-lactic acid) microspheres: in vitro degradation study.
    Biomacromolecules, 2006, Volume: 7, Issue:7

    Topics: Calorimetry, Differential Scanning; Holmium; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Particle Size; Polyesters; Polymers; Solubility; Spectrophotometry, Infrared

2006
Long-term toxicity of holmium-loaded poly(L-lactic acid) microspheres in rats.
    Biomaterials, 2007, Volume: 28, Issue:31

    Topics: Animals; Body Weight; Drug Carriers; Holmium; Lactic Acid; Liver; Male; Materials Testing; Microspheres; Polyesters; Polymers; Rats; Rats, Wistar

2007
Clinical effects of transcatheter hepatic arterial embolization with holmium-166 poly(L-lactic acid) microspheres in healthy pigs.
    European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:7

    Topics: Animals; Catheterization; Embolization, Therapeutic; Female; Hepatic Artery; Holmium; Humans; Lactic Acid; Liver; Liver Neoplasms; Magnetic Resonance Angiography; Microspheres; Polyesters; Polymers; Radioisotopes; Radiopharmaceuticals; Radiotherapy Dosage; Swine; Tissue Distribution

2008
Neutron activation of holmium poly(L-lactic acid) microspheres for hepatic arterial radio-embolization: a validation study.
    Biomedical microdevices, 2009, Volume: 11, Issue:4

    Topics: Animals; Calorimetry, Differential Scanning; Embolization, Therapeutic; Hepatic Artery; Holmium; Humans; Lactic Acid; Liver Neoplasms; Microscopy, Electron, Scanning; Microspheres; Neutrons; Particle Size; Polyesters; Polymers; Time Factors

2009
Holmium-166 poly(L-lactic acid) microsphere radioembolisation of the liver: technical aspects studied in a large animal model.
    European radiology, 2010, Volume: 20, Issue:4

    Topics: Animals; Brachytherapy; Disease Models, Animal; Drug Carriers; Holmium; Humans; Lactic Acid; Liver; Microspheres; Polyesters; Polymers; Radioisotopes; Radiopharmaceuticals; Swine; Tissue Distribution

2010
Magnetic resonance imaging-based radiation-absorbed dose estimation of 166Ho microspheres in liver radioembolization.
    International journal of radiation oncology, biology, physics, 2012, Jul-01, Volume: 83, Issue:3

    Topics: Algorithms; Autoradiography; Embolization, Therapeutic; Holmium; Humans; Lactic Acid; Liver; Liver Neoplasms; Magnetic Resonance Imaging; Microspheres; Monte Carlo Method; Phantoms, Imaging; Polyesters; Polymers; Radioisotopes; Radiotherapy Dosage; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed

2012
Production and characterization of 166Ho polylactic acid microspheres.
    Journal of labelled compounds & radiopharmaceuticals, 2016, Volume: 59, Issue:1

    Topics: Animals; Holmium; Hydroxybutyrates; Lactic Acid; Microspheres; Pentanones; Polyesters; Polymers; Radioisotopes; Radiopharmaceuticals; Rats; Tissue Distribution

2016