hoe 694 has been researched along with ethylisopropylamiloride in 22 studies
| Studies (hoe 694) | Trials (hoe 694) | Recent Studies (post-2010) (hoe 694) | Studies (ethylisopropylamiloride) | Trials (ethylisopropylamiloride) | Recent Studies (post-2010) (ethylisopropylamiloride) |
|---|---|---|---|---|---|
| 120 | 0 | 4 | 599 | 0 | 75 |
| Protein | Taxonomy | hoe 694 (IC50) | ethylisopropylamiloride (IC50) |
|---|---|---|---|
| Sodium/hydrogen exchanger 1 | Homo sapiens (human) | 0.8 | |
| Sodium/hydrogen exchanger 1 | Oryctolagus cuniculus (rabbit) | 0.02 | |
| Sodium/hydrogen exchanger 1 | Rattus norvegicus (Norway rat) | 0.01 | |
| Sodium/hydrogen exchanger 3 | Rattus norvegicus (Norway rat) | 2.4 | |
| Sodium/hydrogen exchanger 2 | Oryctolagus cuniculus (rabbit) | 0.5 | |
| Sodium/hydrogen exchanger 5 | Homo sapiens (human) | 0.42 | |
| Sodium/hydrogen exchanger | Amphiuma tridactylum (three-toed salamander) | 8.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (50.00) | 18.2507 |
| 2000's | 11 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Avkiran, M; Hearse, DJ; Ibuki, C; Yasutake, M | 1 |
| Albus, U; Englert, HC; Lang, HJ; Linz, W; Martorana, PA; Schölkens, BA; Scholz, W | 1 |
| Kranzhöfer, R; Kübler, W; Lang, HJ; Metz, J; Pestel, E; Schirmer, J; Schömig, A; von Hodenberg, E | 1 |
| Kandasamy, RA; Orlowski, J | 1 |
| Liu, J; Shiga, N; Wangemann, P | 1 |
| Ko, Y; Sachinidis, A; Seewald, S; Seul, C; Vetter, H | 1 |
| Bril, A; Khandoudi, N; Laville, MP | 1 |
| Brew, BK; Cook, DI; Field, MJ; Györy, AZ; Johnson, DW; Pollock, CA; Poronnik, P | 1 |
| Banerjee, A; Cain, BS; Cleveland, JC; Harken, AH; Meldrum, DR; Rehring, TF; Shapiro, JI | 1 |
| Gu, XQ; Haddad, GG; Ma, E; Yao, H | 1 |
| Drumm, K; Freudinger, R; Gassner, B; Gekle, M; Mildenberger, S; Silbernagl, S | 1 |
| Numata, M; Orlowski, J; Shull, GE; Szabó, EZ | 1 |
| Baum, M; Choi, JY; Lee, MG; Muallem, S; Schultheis, PJ; Shah, M; Shull, GE | 1 |
| Alper, SL; Klein, M; Schuricht, B; Schwab, A; Seeger, P | 1 |
| Chattou, S; Coulombe, A; Diacono, J; Feuvray, D; John, G; Le Grand, B | 1 |
| Aschenbach, JR; Gäbel, G; Müller, F | 1 |
| Binder, HJ; Geibel, J; Rajendran, VM | 1 |
| Duquette, RA; Wray, S | 1 |
| Drumm, K; Gassner, B; Gekle, M; Silbernagl, S | 1 |
| Aronson, PS; Giebisch, G; Hropot, M; Wang, T | 1 |
| Duranton, C; Huber, SM; Lang, F; Lang, KS; Myssina, S; Tanneur, V; Wieder, T | 1 |
| Demaurex, N; Park, KS; Poburko, D; Wollheim, CB | 1 |
22 other study(ies) available for hoe 694 and ethylisopropylamiloride
| Article | Year |
|---|---|
Na+/H+ exchange and reperfusion arrhythmias: protection by intracoronary infusion of a novel inhibitor.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Circulation; Electrocardiography; Guanidines; Heart Rate; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sulfones; Ventricular Fibrillation | 1994 |
Hoe 694, a new Na+/H+ exchange inhibitor and its effects in cardiac ischaemia.
Topics: Adenosine Triphosphate; Amiloride; Anesthesia; Animals; Blood Platelets; Cattle; Endothelium, Vascular; Erythrocyte Membrane; Female; Glycogen; Guanidines; In Vitro Techniques; Ion Exchange; Male; Myocardial Ischemia; Phosphocreatine; Potassium; Rabbits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium; Sulfones | 1993 |
Suppression of neointimal thickening and smooth muscle cell proliferation after arterial injury in the rat by inhibitors of Na(+)-H+ exchange.
Topics: Amiloride; Animals; Arteries; Carrier Proteins; Catheterization; Cell Division; Guanidines; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Sulfones; Wounds, Nonpenetrating | 1993 |
Delineation of transmembrane domains of the Na+/H+ exchanger that confer sensitivity to pharmacological antagonists.
Topics: Amiloride; Animals; Biological Transport; Cimetidine; DNA, Complementary; Enzyme Inhibitors; Guanidines; Kinetics; Ligands; Membrane Glycoproteins; Rats; Recombinant Fusion Proteins; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Structure-Activity Relationship; Sulfones | 1996 |
Vestibular dark cells contain the Na+/H+ exchanger NHE-1 in the basolateral membrane.
Topics: Amiloride; Animals; Basilar Membrane; Cell Size; Corpus Striatum; Diuretics; Epithelium; Fluoresceins; Fluorescent Dyes; Fluorometry; Gerbillinae; Guanidines; Hydrogen-Ion Concentration; Propionates; Sodium-Hydrogen Exchangers; Structure-Activity Relationship; Sulfones; Vestibule, Labyrinth | 1996 |
Activation of Na+/H+ exchanger is not involved in the PDGF-BB-induced DNA-synthesis in vascular smooth muscle cells.
Topics: Amiloride; Animals; Aorta, Thoracic; Becaplermin; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Guanidines; Hydrogen-Ion Concentration; Kinetics; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Inbred WKY; Recombinant Proteins; Sodium; Sodium-Hydrogen Exchangers; Sulfones | 1996 |
Protective effect of the sodium/hydrogen exchange inhibitors during global low-flow ischemia.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Cardiac Output; Energy Metabolism; Guanidines; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sulfones | 1996 |
Insulin-like growth factor I stimulates apical sodium/hydrogen exchange in human proximal tubule cells.
Topics: Adult; Amiloride; Cell Division; Cells, Cultured; Culture Media, Serum-Free; DNA; Female; Fluoresceins; Fluorescent Dyes; Guanidines; Humans; Insulin-Like Growth Factor I; Kidney Tubules, Proximal; Kinetics; Male; Middle Aged; Sodium; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Sulfones; Thymidine | 1997 |
Mechanisms of pH preservation during global ischemia in preconditioned rat heart: roles for PKC and NHE.
Topics: Acidosis; Adenosine Triphosphate; Adrenergic alpha-Agonists; Amiloride; Animals; Guanidines; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Kinetics; Male; Myocardial Ischemia; Phenylephrine; Phosphates; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfones | 1998 |
Intracellular pH regulation of CA1 neurons in Na(+)/H(+) isoform 1 mutant mice.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonium Chloride; Animals; Ataxia; Benzopyrans; Bicarbonates; Carbon Dioxide; Coloring Agents; Guanidines; Hydrogen-Ion Concentration; Intracellular Fluid; Ion Transport; Mice; Mice, Knockout; Mice, Neurologic Mutants; Microscopy, Confocal; Naphthols; Neurons; Protein Isoforms; Protons; Rhodamines; Sodium; Sodium-Hydrogen Exchangers; Sulfones | 1999 |
Inhibition of Na+-H+ exchange impairs receptor-mediated albumin endocytosis in renal proximal tubule-derived epithelial cells from opossum.
Topics: Amiloride; Animals; Binding Sites; Cell Membrane; Cytosol; Endocytosis; Endosomes; Epithelial Cells; Guanidines; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Lysosomes; Opossums; Propionates; Receptors, Cell Surface; Serum Albumin; Sodium; Sodium-Hydrogen Exchangers; Sulfones | 1999 |
Kinetic and pharmacological properties of human brain Na(+)/H(+) exchanger isoform 5 stably expressed in Chinese hamster ovary cells.
Topics: Adenosine Triphosphate; Amiloride; Animals; Brain; CHO Cells; Cimetidine; Cricetinae; Guanidines; Harmaline; Humans; Hydrogen-Ion Concentration; Kinetics; Lithium; Membrane Proteins; Potassium; Protein Isoforms; Sodium Radioisotopes; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones; Transfection | 2000 |
Novel amiloride-sensitive sodium-dependent proton secretion in the mouse proximal convoluted tubule.
Topics: Amiloride; Animals; Guanidines; Kidney Tubules, Proximal; Mice; Mice, Inbred C57BL; Mice, Knockout; Protons; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones | 2000 |
Polarization of Na(+)/H(+) and Cl(-)/HCO (3)(-) exchangers in migrating renal epithelial cells.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Antiporters; Biological Transport; Cell Line; Cell Movement; Cell Polarity; Cell Size; Chloride-Bicarbonate Antiporters; Dogs; Epithelial Cells; Guanidines; Hydrogen-Ion Concentration; Intercellular Signaling Peptides and Proteins; Kidney; Osmotic Pressure; Peptides; Salts; Sodium-Hydrogen Exchangers; Spider Venoms; Sulfones; Water | 2000 |
Slowly inactivating component of sodium current in ventricular myocytes is decreased by diabetes and partially inhibited by known Na(+)-H(+)Exchange blockers.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Guanidines; Heart Ventricles; Lysophosphatidylcholines; Male; Myocardium; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium Channels; Sodium-Hydrogen Exchangers; Streptozocin; Sulfones; Tetrodotoxin; Veratrine | 2000 |
Role of Na+/H+ exchange and HCO3- transport in pHi recovery from intracellular acid load in cultured epithelial cells of sheep rumen.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Animals; Anti-Arrhythmia Agents; Bicarbonates; Biological Transport; Butyrates; Carbon Dioxide; Cell Culture Techniques; Cells, Cultured; Epithelial Cells; Fluoresceins; Guanidines; Hydrogen-Ion Concentration; Rumen; Sheep; Sodium-Hydrogen Exchangers; Sulfones | 2000 |
Characterization of apical membrane Cl-dependent Na/H exchange in crypt cells of rat distal colon.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Cell Membrane; Chloride Channels; Chlorides; Colon; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Guanidines; Intestinal Mucosa; Ion Transport; Nitrobenzoates; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Sulfones | 2001 |
pH regulation and buffering power in gastric smooth muscle.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acid-Base Equilibrium; Amiloride; Animals; Anti-Arrhythmia Agents; Buffers; Butyrates; Diuretics; Gastric Emptying; Gastric Mucosa; Guanidines; Guinea Pigs; Hydrogen-Ion Concentration; Methylamines; Muscle, Smooth; Rats; Sodium; Sulfones | 2001 |
Inhibition of Na superset+/H superset+ exchange decreases albumin-induced NF-kappaB activation in renal proximal tubular cell lines (OK and LLC-PK1 cells).
Topics: Amiloride; Animals; Cell Line; Chlorpromazine; DNA; Endocytosis; Guanidines; Kidney Tubules, Proximal; LLC-PK1 Cells; NF-kappa B; Opossums; Serum Albumin, Bovine; Sodium-Hydrogen Exchangers; Sulfones; Swine; Tetradecanoylphorbol Acetate | 2001 |
Role of NHE isoforms in mediating bicarbonate reabsorption along the nephron.
Topics: Absorption; Amiloride; Animals; Bicarbonates; Biological Transport; Culture Techniques; Guanidines; Kidney Tubules, Distal; Kidney Tubules, Proximal; Loop of Henle; Male; Methacrylates; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones | 2001 |
Inhibition of erythrocyte cation channels and apoptosis by ethylisopropylamiloride.
Topics: Amiloride; Annexins; Apoptosis; Cations; Cell Size; Dose-Response Relationship, Drug; Erythrocytes; Guanidines; Humans; In Vitro Techniques; Ion Channels; Osmotic Pressure; Patch-Clamp Techniques; Sulfones | 2003 |
Amiloride derivatives induce apoptosis by depleting ER Ca(2+) stores in vascular endothelial cells.
Topics: Amiloride; Antigens, Differentiation; Apoptosis; Calcium; Cell Cycle Proteins; Diuretics; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Endothelial Cells; Enzyme Inhibitors; Guanidines; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Protein Phosphatase 1; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium-Hydrogen Exchangers; Sulfones; Thapsigargin; Transcription Factor CHOP; Transcription, Genetic | 2009 |