hoe 694 has been researched along with amiloride in 52 studies
| Studies (hoe 694) | Trials (hoe 694) | Recent Studies (post-2010) (hoe 694) | Studies (amiloride) | Trials (amiloride) | Recent Studies (post-2010) (amiloride) |
|---|---|---|---|---|---|
| 120 | 0 | 4 | 7,584 | 339 | 788 |
| Protein | Taxonomy | hoe 694 (IC50) | amiloride (IC50) |
|---|---|---|---|
| Urokinase-type plasminogen activator | Homo sapiens (human) | 4.7 | |
| Urokinase-type plasminogen activator | Mus musculus (house mouse) | 2.3 | |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | 3.909 | |
| Sodium/hydrogen exchanger 1 | Rattus norvegicus (Norway rat) | 1 | |
| Amiloride-sensitive sodium channel subunit alpha | Homo sapiens (human) | 0.776 | |
| Sodium/hydrogen exchanger 2 | Oryctolagus cuniculus (rabbit) | 1 | |
| Acid-sensing ion channel 3 | Homo sapiens (human) | 4.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 30 (57.69) | 18.2507 |
| 2000's | 20 (38.46) | 29.6817 |
| 2010's | 2 (3.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lang, HJ; Popp, R; Schmid, A; Scholz, W | 1 |
| du Toit, EF; Opie, LH | 1 |
| Burckhardt, BC; Busch, S; Siffert, W | 1 |
| Avkiran, M; Hearse, DJ; Ibuki, C; Yasutake, M | 1 |
| Flameng, W; Hendrikx, M; Lauweryns, J; Mubagwa, K; Overloop, K; Van Hecke, P; Van Lommel, A; Vanstapel, F; Verbeken, E; Verdonck, F | 1 |
| Counillon, L; Lang, HJ; Pouysségur, J; Scholz, W | 1 |
| Albus, U; Englert, HC; Lang, HJ; Linz, W; Martorana, PA; Schölkens, BA; Scholz, W | 1 |
| Kranzhöfer, R; Kübler, W; Lang, HJ; Metz, J; Pestel, E; Schirmer, J; Schömig, A; von Hodenberg, E | 1 |
| Kandasamy, RA; Orlowski, J | 1 |
| Avkiran, M; Hearse, DJ; Shimada, Y | 1 |
| Liu, J; Shiga, N; Wangemann, P | 1 |
| Loh, SH; Sun, B; Vaughan-Jones, RD | 1 |
| Ko, Y; Sachinidis, A; Seewald, S; Seul, C; Vetter, H | 1 |
| Bril, A; Khandoudi, N; Laville, MP | 1 |
| John, GW; Le Grand, B; Marty, A; Talmant, JM | 1 |
| Counillon, L; Noël, J; Pouysségur, J; Reithmeier, RA | 1 |
| Brew, BK; Cook, DI; Field, MJ; Györy, AZ; Johnson, DW; Pollock, CA; Poronnik, P | 1 |
| Faber, S; Jansen, HW; Lang, HJ; Scholz, W; Weichert, A | 1 |
| Casavola, V; Di Sole, F; Guerra, L; Perlino, E; Reshkin, SJ; Ronco, PM; Valenti, G | 1 |
| D'Souza, SJ; Gan, BS; Grinstein, S; Orlowski, J; Shrode, LD | 1 |
| Banerjee, A; Cain, BS; Cleveland, JC; Harken, AH; Meldrum, DR; Rehring, TF; Shapiro, JI | 1 |
| Frishman, WH; Gurell, D; Levitsky, J | 1 |
| Lee, CO; Woo, SH | 1 |
| Aharonovitz, O; Demaurex, N; Grinstein, S; Woodside, M | 1 |
| de Medina, FS; Donowitz, M; Janecki, AJ; Montrose, MH; Tse, CM; Zweibaum, A | 1 |
| Karmazyn, M | 1 |
| Gu, XQ; Haddad, GG; Ma, E; Yao, H | 1 |
| Drumm, K; Freudinger, R; Gassner, B; Gekle, M; Mildenberger, S; Silbernagl, S | 1 |
| Chow, CW | 1 |
| Good, DW; Watts, BA | 1 |
| Numata, M; Orlowski, J; Shull, GE; Szabó, EZ | 1 |
| Baum, M; Choi, JY; Lee, MG; Muallem, S; Schultheis, PJ; Shah, M; Shull, GE | 1 |
| Alper, SL; Klein, M; Schuricht, B; Schwab, A; Seeger, P | 1 |
| Chattou, S; Coulombe, A; Diacono, J; Feuvray, D; John, G; Le Grand, B | 1 |
| Browning, JA; Wilkins, RJ; Yamazaki, N | 1 |
| Aschenbach, JR; Gäbel, G; Müller, F | 1 |
| Alli, HA; Angle, JM; Black, ED; Donowitz, M; Madara, JL; Tse, CM; Turner, JR; Uchwat, FA; Ward, J | 1 |
| Chew, SB; Leung, GP; Tse, CM; Wong, PY | 1 |
| Binder, HJ; Geibel, J; Rajendran, VM | 1 |
| Abedin, MZ; Abedin, ZR; Giurgiu, DI; Peck, EA; Smith, PR; Su, X | 1 |
| Duquette, RA; Wray, S | 1 |
| Drumm, K; Gassner, B; Gekle, M; Silbernagl, S | 1 |
| Aronson, PS; Giebisch, G; Hropot, M; Wang, T | 1 |
| Cook, DI; Day, ML; Gibb, CA; Harding, EA; Johnson, MH | 1 |
| Galvez, F; Goss, GG; Hawkings, GS; Reid, SD | 1 |
| Duranton, C; Huber, SM; Lang, F; Lang, KS; Myssina, S; Tanneur, V; Wieder, T | 1 |
| Germain, D; Noël, J; Vadnais, J | 1 |
| Browning, JA; Wilkins, RJ | 1 |
| Cala, PM; King, SA; Nygaard, EB; Pedersen, SF; Rigor, RR | 1 |
| Demaurex, N; Park, KS; Poburko, D; Wollheim, CB | 1 |
| Alexander, T; Grinstein, S; Hahn, KM; Hayashi, H; Kim, M; Koivusalo, M; Scott, CC; Touret, N; Welch, C | 1 |
| Martens, H; Noci, B; Rabbani, I; Siegling-Vlitakis, C | 1 |
3 review(s) available for hoe 694 and amiloride
| Article | Year |
|---|---|
Sodium ion/hydrogen ion exchange inhibition: a new pharmacologic approach to myocardial ischemia and reperfusion injury.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Diuretics; Guanidines; Humans; Myocardial Ischemia; Myocardial Reperfusion Injury; Sodium-Hydrogen Exchangers; Sulfones | 1998 |
Mechanisms of protection of the ischemic and reperfused myocardium by sodium-hydrogen exchange inhibition.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Diuretics; Guanidines; Humans; Myocardial Reperfusion Injury; Sodium-Hydrogen Exchangers; Sulfones | 1999 |
Regulation and intracellular localization of the epithelial isoforms of the Na+/H+ exchangers NHE2 and NHE3.
Topics: Adenosine Triphosphate; Amiloride; Animals; Cimetidine; Clonidine; Epithelial Cells; Guanidines; Ion Transport; Kidney; Phosphorylation; Protein Isoforms; Sodium-Hydrogen Exchangers; Sulfones | 1999 |
49 other study(ies) available for hoe 694 and amiloride
| Article | Year |
|---|---|
Na+/H+ exchange in porcine cerebral capillary endothelial cells is inhibited by a benzoylguanidine derivative.
Topics: Amiloride; Animals; Capillaries; Carrier Proteins; Cells, Cultured; Cerebrovascular Circulation; Endothelium, Vascular; Fluoresceins; Fluorescent Dyes; Guanidines; Hydrogen-Ion Concentration; Kinetics; Sodium; Sodium-Hydrogen Exchangers; Sulfones; Swine | 1992 |
Role for the Na+/H+ exchanger in reperfusion stunning in isolated perfused rat heart.
Topics: Amiloride; Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Coronary Circulation; Electrolytes; Guanidines; In Vitro Techniques; Myocardial Stunning; Rats; Reperfusion Injury; Sodium-Hydrogen Exchangers; Sulfones | 1993 |
Expression of the human sodium/proton exchanger NHE-1 in Xenopus laevis oocytes enhances sodium/proton exchange activity and establishes sodium/lithium countertransport.
Topics: Amiloride; Ammonium Chloride; Animals; Antiporters; Female; Gene Expression; Gene Transfer Techniques; Guanidines; Humans; Hydrogen-Ion Concentration; Kinetics; Lithium; Nickel; Oocytes; Phloretin; RNA, Complementary; Sodium; Sodium-Hydrogen Exchangers; Sulfones; Xenopus laevis | 1995 |
Na+/H+ exchange and reperfusion arrhythmias: protection by intracoronary infusion of a novel inhibitor.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Circulation; Electrocardiography; Guanidines; Heart Rate; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sulfones; Ventricular Fibrillation | 1994 |
New Na(+)-H+ exchange inhibitor HOE 694 improves postischemic function and high-energy phosphate resynthesis and reduces Ca2+ overload in isolated perfused rabbit heart.
Topics: Adenosine Triphosphate; Amiloride; Animals; Calcium; Female; Guanidines; Hemodynamics; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Perfusion; Rabbits; Sodium-Hydrogen Exchangers; Sulfones | 1994 |
Pharmacological characterization of stably transfected Na+/H+ antiporter isoforms using amiloride analogs and a new inhibitor exhibiting anti-ischemic properties.
Topics: Amiloride; Animals; Cell Line; Cricetinae; Cricetulus; DNA, Complementary; Guanidines; Myocardial Ischemia; Recombinant Proteins; Sodium-Hydrogen Exchangers; Sulfones; Transfection | 1993 |
Hoe 694, a new Na+/H+ exchange inhibitor and its effects in cardiac ischaemia.
Topics: Adenosine Triphosphate; Amiloride; Anesthesia; Animals; Blood Platelets; Cattle; Endothelium, Vascular; Erythrocyte Membrane; Female; Glycogen; Guanidines; In Vitro Techniques; Ion Exchange; Male; Myocardial Ischemia; Phosphocreatine; Potassium; Rabbits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium; Sulfones | 1993 |
Suppression of neointimal thickening and smooth muscle cell proliferation after arterial injury in the rat by inhibitors of Na(+)-H+ exchange.
Topics: Amiloride; Animals; Arteries; Carrier Proteins; Catheterization; Cell Division; Guanidines; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Sulfones; Wounds, Nonpenetrating | 1993 |
Delineation of transmembrane domains of the Na+/H+ exchanger that confer sensitivity to pharmacological antagonists.
Topics: Amiloride; Animals; Biological Transport; Cimetidine; DNA, Complementary; Enzyme Inhibitors; Guanidines; Kinetics; Ligands; Membrane Glycoproteins; Rats; Recombinant Fusion Proteins; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Structure-Activity Relationship; Sulfones | 1996 |
Impact of extracellular buffer composition on cardioprotective efficacy of Na+/H+ exchanger inhibitors.
Topics: Amiloride; Animals; Bicarbonates; Buffers; Dose-Response Relationship, Drug; Extracellular Space; Guanidines; Heart; HEPES; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sulfones | 1996 |
Vestibular dark cells contain the Na+/H+ exchanger NHE-1 in the basolateral membrane.
Topics: Amiloride; Animals; Basilar Membrane; Cell Size; Corpus Striatum; Diuretics; Epithelium; Fluoresceins; Fluorescent Dyes; Fluorometry; Gerbillinae; Guanidines; Hydrogen-Ion Concentration; Propionates; Sodium-Hydrogen Exchangers; Structure-Activity Relationship; Sulfones; Vestibule, Labyrinth | 1996 |
Effect of Hoe 694, a novel Na(+)-H+ exchange inhibitor, on intracellular pH regulation in the guinea-pig ventricular myocyte.
Topics: Amiloride; Animals; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; Heart; Hydrogen-Ion Concentration; Sodium-Hydrogen Exchangers; Sulfones | 1996 |
Activation of Na+/H+ exchanger is not involved in the PDGF-BB-induced DNA-synthesis in vascular smooth muscle cells.
Topics: Amiloride; Animals; Aorta, Thoracic; Becaplermin; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Guanidines; Hydrogen-Ion Concentration; Kinetics; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Inbred WKY; Recombinant Proteins; Sodium; Sodium-Hydrogen Exchangers; Sulfones | 1996 |
Protective effect of the sodium/hydrogen exchange inhibitors during global low-flow ischemia.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Cardiac Output; Energy Metabolism; Guanidines; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sulfones | 1996 |
HOE 694 affords protection versus veratrine contractures in rat atria by Na+ channel blockade.
Topics: Action Potentials; Algorithms; Amiloride; Animals; Diuretics; Dose-Response Relationship, Drug; Guanidines; Heart Atria; Lethal Dose 50; Male; Myocardial Contraction; Rats; Rats, Wistar; Sodium Channels; Sodium-Hydrogen Exchangers; Sulfones; Veratrine | 1996 |
Random mutagenesis reveals a novel site involved in inhibitor interaction within the fourth transmembrane segment of the Na+/H+ exchanger-1.
Topics: Amiloride; Binding Sites; Clone Cells; Cloning, Molecular; DNA, Complementary; Drug Resistance; Fibroblasts; Guanidines; Humans; Membrane Proteins; Mutagenesis; Mutagenesis, Site-Directed; Point Mutation; Protein Structure, Secondary; Sodium; Sodium-Hydrogen Exchangers; Sulfones | 1997 |
Insulin-like growth factor I stimulates apical sodium/hydrogen exchange in human proximal tubule cells.
Topics: Adult; Amiloride; Cell Division; Cells, Cultured; Culture Media, Serum-Free; DNA; Female; Fluoresceins; Fluorescent Dyes; Guanidines; Humans; Insulin-Like Growth Factor I; Kidney Tubules, Proximal; Kinetics; Male; Middle Aged; Sodium; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Sulfones; Thymidine | 1997 |
Synthesis of the highly selective Na+/H+ exchange inhibitors cariporide mesilate and (3-methanesulfonyl-4-piperidino-benzoyl) guanidine methanesulfonate.
Topics: Amiloride; Cell Line; Diuretics; Enzyme Inhibitors; Guanidines; Sodium-Hydrogen Exchangers; Sulfones | 1997 |
Polarized distribution of Na+/H+ exchanger isoforms in rabbit collecting duct cells.
Topics: Amiloride; Animals; Base Sequence; Cell Line; Cell Membrane; Cell Polarity; Cimetidine; Clonidine; DNA Primers; Guanidines; Hydrogen-Ion Concentration; Intracellular Fluid; Kidney Tubules, Collecting; Kinetics; Polymerase Chain Reaction; Protein Kinases; Rabbits; Sodium-Hydrogen Exchangers; Sulfones | 1998 |
Topological analysis of NHE1, the ubiquitous Na+/H+ exchanger using chymotryptic cleavage.
Topics: Amiloride; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Blood Platelets; Carbohydrates; Cell Membrane; Chymotrypsin; Cytosol; Guanidines; Humans; Kinetics; Models, Molecular; Peptide Mapping; Protein Folding; Protein Structure, Secondary; Rats; Recombinant Fusion Proteins; Sodium-Hydrogen Exchangers; Sulfones; Transfection | 1998 |
Mechanisms of pH preservation during global ischemia in preconditioned rat heart: roles for PKC and NHE.
Topics: Acidosis; Adenosine Triphosphate; Adrenergic alpha-Agonists; Amiloride; Animals; Guanidines; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Kinetics; Male; Myocardial Ischemia; Phenylephrine; Phosphates; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfones | 1998 |
Effects of endothelin-1 on Ca2+ signaling in guinea-pig ventricular myocytes: role of protein kinase C.
Topics: Amiloride; Animals; Calcium; Cardiotonic Agents; Cells, Cultured; Electrophysiology; Endothelin-1; Enzyme Inhibitors; Guanidines; Guinea Pigs; Indoles; Male; Maleimides; Myocardial Contraction; Myocardium; Perfusion; Pertussis Toxin; Protein Kinase C; Signal Transduction; Sulfones; Time Factors; Virulence Factors, Bordetella | 1999 |
ATP dependence is not an intrinsic property of Na+/H+ exchanger NHE1: requirement for an ancillary factor.
Topics: Acids; Adenosine Triphosphate; Amiloride; Animals; Dogs; Erythrocyte Membrane; Erythrocytes; Guanidines; Hydrogen-Ion Concentration; Sodium-Hydrogen Exchangers; Sulfones | 1999 |
Development of an endogenous epithelial Na(+)/H(+) exchanger (NHE3) in three clones of caco-2 cells.
Topics: Amiloride; Biotin; Blotting, Western; Caco-2 Cells; Cell Membrane; Clone Cells; Epidermal Growth Factor; Epithelial Cells; Fluorescent Antibody Technique, Indirect; Guanidines; Humans; Intracellular Membranes; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones; Tetradecanoylphorbol Acetate | 1999 |
Intracellular pH regulation of CA1 neurons in Na(+)/H(+) isoform 1 mutant mice.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonium Chloride; Animals; Ataxia; Benzopyrans; Bicarbonates; Carbon Dioxide; Coloring Agents; Guanidines; Hydrogen-Ion Concentration; Intracellular Fluid; Ion Transport; Mice; Mice, Knockout; Mice, Neurologic Mutants; Microscopy, Confocal; Naphthols; Neurons; Protein Isoforms; Protons; Rhodamines; Sodium; Sodium-Hydrogen Exchangers; Sulfones | 1999 |
Inhibition of Na+-H+ exchange impairs receptor-mediated albumin endocytosis in renal proximal tubule-derived epithelial cells from opossum.
Topics: Amiloride; Animals; Binding Sites; Cell Membrane; Cytosol; Endocytosis; Endosomes; Epithelial Cells; Guanidines; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Lysosomes; Opossums; Propionates; Receptors, Cell Surface; Serum Albumin; Sodium; Sodium-Hydrogen Exchangers; Sulfones | 1999 |
Hyposmolality stimulates apical membrane Na(+)/H(+) exchange and HCO(3)(-) absorption in renal thick ascending limb.
Topics: Amiloride; Animals; Benzoquinones; Bicarbonates; Enzyme Inhibitors; Furosemide; Genistein; Guanidines; Lactams, Macrocyclic; Loop of Henle; Male; Mannitol; Osmolar Concentration; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; Signal Transduction; Sodium Chloride; Sodium-Hydrogen Exchangers; Sulfones | 1999 |
Kinetic and pharmacological properties of human brain Na(+)/H(+) exchanger isoform 5 stably expressed in Chinese hamster ovary cells.
Topics: Adenosine Triphosphate; Amiloride; Animals; Brain; CHO Cells; Cimetidine; Cricetinae; Guanidines; Harmaline; Humans; Hydrogen-Ion Concentration; Kinetics; Lithium; Membrane Proteins; Potassium; Protein Isoforms; Sodium Radioisotopes; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones; Transfection | 2000 |
Novel amiloride-sensitive sodium-dependent proton secretion in the mouse proximal convoluted tubule.
Topics: Amiloride; Animals; Guanidines; Kidney Tubules, Proximal; Mice; Mice, Inbred C57BL; Mice, Knockout; Protons; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones | 2000 |
Polarization of Na(+)/H(+) and Cl(-)/HCO (3)(-) exchangers in migrating renal epithelial cells.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Antiporters; Biological Transport; Cell Line; Cell Movement; Cell Polarity; Cell Size; Chloride-Bicarbonate Antiporters; Dogs; Epithelial Cells; Guanidines; Hydrogen-Ion Concentration; Intercellular Signaling Peptides and Proteins; Kidney; Osmotic Pressure; Peptides; Salts; Sodium-Hydrogen Exchangers; Spider Venoms; Sulfones; Water | 2000 |
Slowly inactivating component of sodium current in ventricular myocytes is decreased by diabetes and partially inhibited by known Na(+)-H(+)Exchange blockers.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Guanidines; Heart Ventricles; Lysophosphatidylcholines; Male; Myocardium; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium Channels; Sodium-Hydrogen Exchangers; Streptozocin; Sulfones; Tetrodotoxin; Veratrine | 2000 |
Modulation of Na(+) x H(+) exchange by osmotic shock in isolated bovinearticular chondrocytes.
Topics: Amiloride; Animals; Cartilage, Articular; Cattle; Cells, Cultured; Chondrocytes; Enzyme Inhibitors; Fluoresceins; Guanidines; Hydrogen-Ion Concentration; Intracellular Fluid; Meglumine; Myosin-Light-Chain Kinase; Osmolar Concentration; Osmotic Pressure; Protein Kinase C; Quaternary Ammonium Compounds; Sodium; Sodium-Hydrogen Exchangers; Sucrose; Sulfones | 2000 |
Role of Na+/H+ exchange and HCO3- transport in pHi recovery from intracellular acid load in cultured epithelial cells of sheep rumen.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Animals; Anti-Arrhythmia Agents; Bicarbonates; Biological Transport; Butyrates; Carbon Dioxide; Cell Culture Techniques; Cells, Cultured; Epithelial Cells; Fluoresceins; Guanidines; Hydrogen-Ion Concentration; Rumen; Sheep; Sodium-Hydrogen Exchangers; Sulfones | 2000 |
Transepithelial resistance can be regulated by the intestinal brush-border Na(+)/H(+) exchanger NHE3.
Topics: Acids; Alkalies; Amiloride; Animals; Anti-Ulcer Agents; Antihypertensive Agents; Biological Transport; Caco-2 Cells; Cimetidine; Clonidine; Cytoplasm; Diuretics; Electric Impedance; Electrophysiology; Epithelial Cells; Glucose; Guanidines; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Methacrylates; Microvilli; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones; Tight Junctions | 2000 |
Expression of multiple Na+/H+ exchanger isoforms in cultured epithelial cells from rat efferent duct and cauda epididymidis.
Topics: Amiloride; Animals; Blotting, Western; Cell Membrane; Cells, Cultured; Diuretics; Epididymis; Epithelial Cells; Guanidines; Immunohistochemistry; Isoenzymes; Male; Methacrylates; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; Seminiferous Tubules; Sodium-Hydrogen Exchangers; Sulfones | 2001 |
Characterization of apical membrane Cl-dependent Na/H exchange in crypt cells of rat distal colon.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Cell Membrane; Chloride Channels; Chlorides; Colon; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Guanidines; Intestinal Mucosa; Ion Transport; Nitrobenzoates; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Sulfones | 2001 |
Characterization of NA+/H+ exchanger isoform (NHE1, NH32 and NHE3) expression in prairie dog gallbladder.
Topics: Amiloride; Animals; Biological Transport, Active; Blotting, Northern; Cholelithiasis; Disease Models, Animal; Electrophysiology; Epithelial Cells; Gallbladder; Guanidines; Immunoblotting; Male; Protein Isoforms; RNA; Sciuridae; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones | 2001 |
pH regulation and buffering power in gastric smooth muscle.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acid-Base Equilibrium; Amiloride; Animals; Anti-Arrhythmia Agents; Buffers; Butyrates; Diuretics; Gastric Emptying; Gastric Mucosa; Guanidines; Guinea Pigs; Hydrogen-Ion Concentration; Methylamines; Muscle, Smooth; Rats; Sodium; Sulfones | 2001 |
Inhibition of Na superset+/H superset+ exchange decreases albumin-induced NF-kappaB activation in renal proximal tubular cell lines (OK and LLC-PK1 cells).
Topics: Amiloride; Animals; Cell Line; Chlorpromazine; DNA; Endocytosis; Guanidines; Kidney Tubules, Proximal; LLC-PK1 Cells; NF-kappa B; Opossums; Serum Albumin, Bovine; Sodium-Hydrogen Exchangers; Sulfones; Swine; Tetradecanoylphorbol Acetate | 2001 |
Role of NHE isoforms in mediating bicarbonate reabsorption along the nephron.
Topics: Absorption; Amiloride; Animals; Bicarbonates; Biological Transport; Culture Techniques; Guanidines; Kidney Tubules, Distal; Kidney Tubules, Proximal; Loop of Henle; Male; Methacrylates; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones | 2001 |
Developmental changes in the management of acid loads during preimplantation mouse development.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acids; Amiloride; Animals; Blastocyst; Embryonic Development; Female; Guanidines; Hydrogen; Ion Transport; Lithium; Mice; Mice, Inbred Strains; Oocytes; Pregnancy; Protein Isoforms; Sodium-Hydrogen Exchangers; Sulfones; Trophoblasts; Zinc | 2002 |
Localization and characterization of phenamil-sensitive Na+ influx in isolated rainbow trout gill epithelial cells.
Topics: Amiloride; Animals; Anti-Bacterial Agents; Biological Transport; Bumetanide; Epithelial Cells; Female; Gills; Guanidines; Hydrogen-Ion Concentration; Macrolides; Male; Mitochondria; Models, Biological; Oncorhynchus mykiss; Ouabain; Peanut Agglutinin; Sodium; Sodium Radioisotopes; Sulfones | 2003 |
Inhibition of erythrocyte cation channels and apoptosis by ethylisopropylamiloride.
Topics: Amiloride; Annexins; Apoptosis; Cations; Cell Size; Dose-Response Relationship, Drug; Erythrocytes; Guanidines; Humans; In Vitro Techniques; Ion Channels; Osmotic Pressure; Patch-Clamp Techniques; Sulfones | 2003 |
Glutamate 346 of human Na+-H+ exchanger NHE1 is crucial for modulating both the affinity for Na+ and the interaction with amiloride derivatives.
Topics: Amiloride; Amino Acid Substitution; Animals; Binding Sites; Cell Line; Cricetinae; Drug Resistance; Genetic Variation; Glutamic Acid; Guanidines; Humans; Mutagenesis, Site-Directed; Potassium; Protons; RNA, Messenger; Sodium; Sodium-Hydrogen Exchangers; Sulfones | 2003 |
Mechanisms contributing to intracellular pH homeostasis in an immortalised human chondrocyte cell line.
Topics: Acidosis; Amiloride; Bicarbonates; Buffers; Cell Line; Chondrocytes; Guanidines; HEPES; Homeostasis; Humans; Hydrogen-Ion Concentration; Sodium; Sulfones | 2004 |
NHE1 inhibition by amiloride- and benzoylguanidine-type compounds. Inhibitor binding loci deduced from chimeras of NHE1 homologues with endogenous differences in inhibitor sensitivity.
Topics: Amiloride; Animals; Binding Sites; Cation Transport Proteins; Cell Line; Cricetinae; Cricetulus; Flounder; Guanidines; Humans; Mutation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sodium Channel Blockers; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Species Specificity; Sulfones; Urodela | 2007 |
Amiloride derivatives induce apoptosis by depleting ER Ca(2+) stores in vascular endothelial cells.
Topics: Amiloride; Antigens, Differentiation; Apoptosis; Calcium; Cell Cycle Proteins; Diuretics; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Endothelial Cells; Enzyme Inhibitors; Guanidines; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Protein Phosphatase 1; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium-Hydrogen Exchangers; Sulfones; Thapsigargin; Transcription Factor CHOP; Transcription, Genetic | 2009 |
Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling.
Topics: Actin Depolymerizing Factors; Amiloride; Animals; cdc42 GTP-Binding Protein; Cell Line; Cytosol; Enzyme Activation; Epidermal Growth Factor; GRB2 Adaptor Protein; Guanidines; Humans; Hydrogen-Ion Concentration; Hydrolysis; Intracellular Membranes; Phosphorylation; Pinocytosis; Proto-Oncogene Proteins c-akt; Rabbits; rac1 GTP-Binding Protein; Recombinant Fusion Proteins; Signal Transduction; Sodium; Sodium-Hydrogen Exchangers; Sulfones | 2010 |
Evidence for NHE3-mediated Na transport in sheep and bovine forestomach.
Topics: Amiloride; Animals; Cattle; Epithelium; Guanidines; Protein Isoforms; Rumen; Sheep; Sodium; Sodium Channel Blockers; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones | 2011 |