histrionicotoxin has been researched along with triphenylmethylphosphonium* in 2 studies
1 review(s) available for histrionicotoxin and triphenylmethylphosphonium
| Article | Year |
|---|---|
The nicotinic acetylcholine receptor and its ion channel.
Topics: Amino Acid Sequence; Amphibian Venoms; Antibodies, Monoclonal; Glycoproteins; Humans; Ion Channels; Macromolecular Substances; Microscopy, Electron; Molecular Weight; Onium Compounds; Phosphoproteins; Protein Biosynthesis; Protein Conformation; Protein Kinases; Receptors, Nicotinic; RNA, Messenger; Tritium; Trityl Compounds | 1986 |
1 other study(ies) available for histrionicotoxin and triphenylmethylphosphonium
| Article | Year |
|---|---|
The reaction site of a non-competitive antagonist in the delta-subunit of the nicotinic acetylcholine receptor.
A site in the primary structure of the nicotinic acetylcholine receptor from Torpedo marmorata covalently labeled with the non-competitive antagonist [3H]triphenylmethylphosphonium (TPMP+) was localized. The label was found in position 262 of the delta-polypeptide chain. This site is specifically labeled in the presence of the agonist carbamoylcholine. Labeling is prevented by the non-competitive antagonist histrionicotoxin. Position 262, probably a serine, is located in the highly conserved membrane-spanning helix M2 (according to the predicted folding scheme of Finer-Moore and Stroud (1984). The relationship of this site to the receptor's ion channel and its regulation is discussed. Topics: Amino Acid Sequence; Amphibian Venoms; Animals; Binding Sites; Carbachol; Electric Organ; Kinetics; Macromolecular Substances; Onium Compounds; Receptors, Nicotinic; Torpedo; Trityl Compounds | 1986 |