histidine has been researched along with methotrexate in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (57.58) | 18.7374 |
| 1990's | 4 (12.12) | 18.2507 |
| 2000's | 2 (6.06) | 29.6817 |
| 2010's | 6 (18.18) | 24.3611 |
| 2020's | 2 (6.06) | 2.80 |
| Authors | Studies |
|---|---|
| Ishchenko, AV; Shakhnovich, EI | 1 |
| Greenfield, NJ; Hoogsteen, K; Poe, M; Williams, MN | 1 |
| Hoogsteen, K; Matthews, DA; Poe, M | 1 |
| Brown, KA; Farnum, MF; Howell, EE; Kraut, J; Warren, MS | 1 |
| Birdsall, B; Bowden, K; Feeney, J; Hall, AD; Roberts, GC | 1 |
| Greenfield, NJ | 1 |
| Wilmanns, W | 1 |
| Fukui, K; Halprin, K; Marks, R | 1 |
| Bagshawe, KD; Hughes, M | 1 |
| van Roon-Djordjević, B | 1 |
| Gerron, GG; Howard, CH; Rudman, D; Vogler, WR | 1 |
| Ishihara, S | 1 |
| Lin, MS; Winchell, HS | 1 |
| Evans, EA | 1 |
| Antonjuk, DJ; Birdsall, B; Cheung, HT; Clore, GM; Feeney, J; Gronenborn, A; Roberts, GC; Tran, TQ | 1 |
| Birdsall, B; Burgen, AS; Feeney, J; Gronenborn, A; Kaptein, R; Roberts, GC | 1 |
| Birdsall, B; Burgen, AS; Feeney, J; Gronenborn, A; Roberts, GC; Wyeth, P | 1 |
| Newman, EM; Nierenberg, DW; Santi, DV | 1 |
| Fan, CC; Huennekens, FM; Vitols, KS | 1 |
| Schalinske, KL; Steele, RD | 1 |
| Kalman, TI; Mao, Z; Pan, J | 1 |
| Azem, A; Horst, M; Oppliger, W; Rospert, S; Schatz, G; Schönfeld, HJ | 1 |
| HAYES, DM; MEREDITH, JH; WILKINS, FB | 1 |
| BIGNOTTI, G; TOGNELLA, S | 1 |
| Drummond, DC; Kirpotin, DB; Marks, JD; Nielsen, UB; Pickering, EM | 1 |
| Guo, L; He, D; Jiang, B; Li, Y; Ma, L; Ouyang, L | 1 |
| Li, Q; Wagner, CR; White, BR | 1 |
| Abolmaali, S; Ashraf, M; Dinarvand, R; Kamali-Sarvestani, E; Tamaddon, A | 1 |
| Abolmaali, SS; Amoozgar, Z; Dinarvand, R; Mohammadi, S; Tamaddon, AM | 1 |
| Abu-Remaileh, M; Cantor, JR; Chan, SH; Freinkman, E; Kanarek, N; Keys, HR; Kunchok, T; Lewis, CA; Sabatini, DM; Schweitzer, LD | 1 |
| Frezza, C | 1 |
| Kanarek, N; Petrova, B | 1 |
| Huang, W; Jia, F; Jiang, Y; Su, W; Wang, H; Wang, X; Yin, Y; Zhang, J | 1 |
1 review(s) available for histidine and methotrexate
| Article | Year |
|---|---|
Potential Benefits and Pitfalls of Histidine Supplementation for Cancer Therapy Enhancement.
Topics: Animals; Dietary Supplements; Folic Acid; Formiminoglutamic Acid; Histidine; Humans; Leukemia; Methotrexate; Neoplasms | 2020 |
32 other study(ies) available for histidine and methotrexate
| Article | Year |
|---|---|
SMall Molecule Growth 2001 (SMoG2001): an improved knowledge-based scoring function for protein-ligand interactions.
Topics: Carbonic Anhydrases; Computing Methodologies; Databases, Factual; Ligands; Metalloendopeptidases; Metals; Molecular Conformation; Protein Binding; Proteins; Quantitative Structure-Activity Relationship; Statistics as Topic; Thermodynamics | 2002 |
Dihydrofolate reductase from a methotrexate-resistant Escherichia coli: proton magnetic resonance studies of complexes with folate and methotrexate.
Topics: Binding Sites; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Methotrexate; Protein Binding; Protein Conformation; Tetrahydrofolate Dehydrogenase | 1975 |
Proton magnetic resonance studies on Escherichia coli dihydrofolate reductase. Assignment of histidine C-2 protons in binary complexes with folates on the basis of the crystal structure with methotrexate and on chemical modifications.
Topics: Binding Sites; Crystallization; Escherichia coli; Folic Acid; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Methotrexate; Models, Molecular; Protein Binding; Protein Conformation; Tetrahydrofolate Dehydrogenase | 1979 |
Investigation of the functional role of tryptophan-22 in Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
Topics: Coenzymes; Deuterium; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Methotrexate; Mutagenesis, Site-Directed; NADP; Protein Binding; Structure-Activity Relationship; Substrate Specificity; Tetrahydrofolate Dehydrogenase; Tryptophan | 1991 |
Interactions between inhibitors of dihydrofolate reductase.
Topics: Benzenesulfonates; Binding Sites; Escherichia coli; Folic Acid Antagonists; Histidine; Hydrogen-Ion Concentration; Kinetics; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Methotrexate; Pyrimidines; Sulfonamides; Trimethoprim | 1989 |
The effect of histidine modification on the activity of dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli B.
Topics: Allosteric Regulation; Allosteric Site; Amino Acids; Anhydrides; Binding Sites; Circular Dichroism; Escherichia coli; Ethyl Ethers; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; Ligands; Methotrexate; Mutation; NADP; Oxidation-Reduction; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tetrahydrofolate Dehydrogenase; Time Factors | 1974 |
[Folate enzymes and thymidilate synthesis in erythrocytes and bone marrow cells under normal and pathologic conditions].
Topics: Bone Marrow; Bone Marrow Cells; DNA; Erythrocytes; Female; FIGLU Test; Folic Acid; Folic Acid Deficiency; Hemoglobinuria, Paroxysmal; Histidine; Humans; Liver Cirrhosis; Methotrexate; Nucleotides; RNA; Tetrahydrofolate Dehydrogenase; Thymidine Kinase; Vitamin B 12 Deficiency | 1968 |
The application of an in vitro technique to the study of epidermal replication and metabolism.
Topics: Culture Techniques; DNA; Folic Acid Antagonists; Growth Inhibitors; Histidine; Humans; Methods; Methotrexate; Nucleosides; Proline; Protein Biosynthesis; Psoriasis; RNA; Skin; Thymidine; Tritium | 1971 |
Serum folate and FIGLU excretion in patients with trophoblastic tumours.
Topics: Adolescent; Adult; Chorionic Gonadotropin; Female; FIGLU Test; Folic Acid; Glutamates; Histidine; Humans; Leucovorin; Methotrexate; Pregnancy; Trophoblastic Neoplasms | 1968 |
Urinary excretion of histidine metabolites as an indication for folic acid and vitamin B 12 deficiency.
Topics: Adolescent; Adult; Aged; Chromatography, Ion Exchange; Chromatography, Thin Layer; Contraceptives, Oral; Electrophoresis; Female; FIGLU Test; Folic Acid Deficiency; Histidine; Humans; Hydantoins; Imidazoles; Male; Methods; Methotrexate; Middle Aged; Propionates; Vitamin B 12 Deficiency | 1972 |
Observations on the plasma amino acids of patients with acute leukemia.
Topics: Acute Disease; Alanine; Amino Acids; Asparaginase; Cytarabine; Glucocorticoids; Glutamine; Histidine; Humans; Indicators and Reagents; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Methionine; Methotrexate; Nitrogen; Proline; Threonine; Vincristine | 1971 |
Clinical and experimental evaluation of urinary histidine derivatives as an index of folic acid metabolism. II. The observation in neoplastic diseases with or without methotrexate administration.
Topics: Adult; Aged; Animals; Blood Cell Count; Blood Platelets; Dogs; Female; FIGLU Test; Folic Acid; Histidine; Humans; Leukocyte Count; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasms | 1969 |
Kinetics of amino acid transport across bone marrow cell membranes.
Topics: Amino Acids; Animals; Biological Transport, Active; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cell Membrane; DNA; Dogs; Extracellular Space; Glucagon; Glutamates; Histidine; Imidazoles; Insulin; Kinetics; Methionine; Methotrexate; Models, Biological; Serine; Time Factors; Tryptophan | 1970 |
Control of self-irradiation decomposition of tritium-labelled compounds at high specific activity.
Topics: Alcohols; Drug Stability; Ethanol; Folic Acid; Formates; Histidine; Leucine; Methotrexate; Nucleosides; Penicillin G; Radiation-Protective Agents; Thymidine; Tritium; Tyrosine; Uridine | 1966 |
A 1H n.m.r. study of the role of the glutamate moiety in the binding of methotrexate to Lactobacillus casei dihydrofolate reductase.
Topics: Folic Acid Antagonists; Glutamates; Histidine; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Methotrexate; Protein Binding; Tetrahydrofolate Dehydrogenase | 1984 |
Photo-CIDNP studies of the influence of ligand binding on the surface accessibility of aromatic residues in dihydrofolate reductase.
Topics: Folic Acid; Histidine; Lacticaseibacillus casei; Lasers; Ligands; Magnetic Resonance Spectroscopy; Methotrexate; NADP; Photochemistry; Protein Binding; Protein Conformation; Tetrahydrofolate Dehydrogenase; Trimethoprim | 1980 |
Histidine residues of Lactobacillus casei dihydrofolate reductase: paramagnetic relaxation and deuterium-exchange studies and partial assignments.
Topics: Histidine; Hydrogen-Ion Concentration; Kinetics; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Methotrexate; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Tetrahydrofolate Dehydrogenase; Trimethoprim | 1980 |
Selective killing of transformed cells by methotrexate with histidine deprivation or with alpha-amino alcohols.
Topics: Animals; Cell Division; Cell Survival; Histidine; Histidinol; Imidazoles; Methotrexate; Mice; Mice, Inbred BALB C; Phenylalanine; Tyrosine | 1983 |
Inhibition of dihydrofolate reductase by methotrexate: a new look at an old problem.
Topics: Animals; Catalysis; Cells, Cultured; Cysteine; Folic Acid Antagonists; Histidine; Kinetics; Leukemia L1210; Methotrexate; Mice; NADP; Structure-Activity Relationship | 1980 |
Methotrexate alters carbon flow through the hepatic folate-dependent one-carbon pool in rats.
Topics: Animals; Body Weight; Carbon; Carbon Radioisotopes; Folic Acid; Histidine; Liver; Male; Methotrexate; Rats; Rats, Sprague-Dawley | 1996 |
Design and synthesis of histidine analogues of folic acid and methotrexate as potential folylpolyglutamate synthetase inhibitors.
Topics: Animals; Cell Division; Folic Acid; Folic Acid Antagonists; Histidine; Humans; Hydrogen-Ion Concentration; Leukemia L1210; Methotrexate; Mice; Peptide Synthases | 1996 |
Sequential action of two hsp70 complexes during protein import into mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Carrier Proteins; Folic Acid Antagonists; Fungal Proteins; Heat-Shock Proteins; Histidine; HSP40 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Intracellular Membranes; L-Lactate Dehydrogenase; L-Lactate Dehydrogenase (Cytochrome); Membrane Proteins; Membrane Transport Proteins; Methotrexate; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Precursor Protein Import Complex Proteins; Molecular Chaperones; Peptides; Protein Binding; Protein Folding; Protein Precursors; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tetrahydrofolate Dehydrogenase | 1997 |
REGIONAL ARTERIAL INFUSION FOR LOCALIZED MALIGNANCIES.
Topics: Blood Platelet Disorders; FIGLU Test; Histidine; Humans; Infusions, Intra-Arterial; Injections; Injections, Intra-Arterial; Leucovorin; Methotrexate; Neoplasms; Pathology; Perfusion; Thrombocytosis; Toxicology | 1964 |
[LABORATORY TESTS FOR VERIFYING STATES OF FOLIC ACID DEFICIENCY IN THE ORGANISM].
Topics: Aminopterin; Anemia; Anemia, Macrocytic; Anticonvulsants; Biological Assay; Blood; Clinical Laboratory Techniques; Folic Acid; Folic Acid Deficiency; Histidine; Humans; Lactobacillus; Leuconostoc; Liver Diseases; Methotrexate; Neoplasms; Nutrition Disorders; Pregnancy; Staphylococcus; Urine; Vitamin B Deficiency | 1964 |
A novel assay for monitoring internalization of nanocarrier coupled antibodies.
Topics: Antibodies, Neoplasm; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Doxorubicin; Histidine; Humans; Immunoglobulin Variable Region; Immunologic Techniques; Ligands; Lipid Bilayers; Lipid Metabolism; Liposomes; Methotrexate; Nickel; Oligopeptides; Receptor, ErbB-2; Sensitivity and Specificity | 2006 |
Synthesis of novel dendrimers having aspartate grafts and their ability to enhance the aqueous solubility of model drugs.
Topics: Aspartic Acid; Dendrimers; Drug Carriers; Histidine; Hydrogen-Ion Concentration; Methotrexate; Naproxen; Peptides; Pharmaceutical Preparations; Solubility; Surface Properties; Temperature; Water | 2010 |
Chemically induced self-assembly of enzyme nanorings.
Topics: Binding Sites; Chromatography, Gel; Cloning, Molecular; Escherichia coli; Gene Expression; Histidine; Humans; Kinetics; Methotrexate; Models, Molecular; Nanoconjugates; Nerve Tissue Proteins; Protein Multimerization; Protein Structure, Tertiary; Recombinant Fusion Proteins; Tetrahydrofolate Dehydrogenase | 2011 |
Stealth Nanogels of Histinylated Poly Ethyleneimine for Sustained Delivery of Methotrexate in Collagen-Induced Arthritis Model.
Topics: Animals; Arthritis, Experimental; Aziridines; Collagen; Drug Carriers; Drug Delivery Systems; Female; Histidine; Methotrexate; Mice; Mice, Inbred C57BL; Nanogels; Polyethylene Glycols; Polyethyleneimine; Polymers | 2015 |
Chemically crosslinked nanogels of PEGylated poly ethyleneimine (l-histidine substituted) synthesized via metal ion coordinated self-assembly for delivery of methotrexate: Cytocompatibility, cellular delivery and antitumor activity in resistant cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle Checkpoints; Drug Carriers; Drug Liberation; Drug Resistance, Neoplasm; Dynamic Light Scattering; Hep G2 Cells; Histidine; Humans; Ions; Magnetic Resonance Spectroscopy; Metals; Methotrexate; Microscopy, Atomic Force; Nanogels; Particle Size; Polyethylene Glycols; Polyethyleneimine; Spectroscopy, Fourier Transform Infrared | 2016 |
Histidine catabolism is a major determinant of methotrexate sensitivity.
Topics: Ammonia-Lyases; Animals; Cell Line, Tumor; CRISPR-Cas Systems; Female; Folic Acid Antagonists; Glutamate Formimidoyltransferase; Histidine; Humans; Male; Methotrexate; Mice; Mice, Inbred NOD; Mice, SCID; Multifunctional Enzymes; Neoplasms; Nucleotides; Reduced Folate Carrier Protein; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Xenograft Model Antitumor Assays | 2018 |
Histidine metabolism boosts cancer therapy.
Topics: Histidine; Humans; Methotrexate; Mutation; Neoplasms; Research | 2018 |
Regulation of Nucleotide Metabolism with Nutrient-Sensing Nanodrugs for Cancer Therapy.
Topics: Animals; Carbon; DNA; Histidine; Humans; Methotrexate; Mice; Nanoparticles; Neoplasms; Nucleotides; Nutrients; RNA | 2022 |